© eurodia industrie 84120 pertuis - france strictly ......• analytical equipment : hplc waters...

Strictly confidential© EURODIA Industrie – 84120 Pertuis - France Strictly confidential

Strictly confidential© EURODIA Industrie – 84120 Pertuis - France

Eurodia designs and realizes complete process solutions,

in the field of purification and fractionation.

Strictly confidential

KEY FIGURES

Set up: 1988

Capital: Founder & Executive team

Shareholder : Mitsubishi Chemicals

Total Staff: 75

R&D: 15% of expenditures dedicated to R&D


Russia

China

MCAS

EURODIA HEADQUARTERSin Pertuis – S/E of France

INTERNATIONAL ORGANIZATION


Valorization of whey Proteins fractionation Milk standardization

Tartaric stabilization of wines and juices pH adjustment of wines and juices Alcohol removal of wines

DAIRY INDUSTRY

WINE AND JUICE INDUSTRIES

Liquid sugar production Demineralization, clarification & decoloration of syrups Purification of specialty sugars and polyols Production of glucose & fructose and oligosaccharides

STARCH AND SUGAR INDUSTRIES

OUR APPLICATIONS


OUR APPLICATIONS

Demineralization & separation of amino acids Purification & deacidification of organic streams Production of organic acids

BIOTECH

Petrochemistry Lithium production Purification of solvent Production of acid and base from salts Electroless nickel plating industry

CHEMICAL INDUSTRIES


Relying on 25 years of experience in process solutions for purification,

EURODIA is launching its new trade name...

Membrane filtrations

IEX – IEX

Chromatography

COMPLETE

PROCESS

SOLUTIONS

IN BIOTECH INDUSTRY...



FERMENTATION

First Generation(Glucose / Saccharose)

Second Generation(Cellulose)

Sugarspurification

DSP

CONCENTRATION

Food applications

Polymers (Plastics)

Bio-Chemistry(solvents, detergents,

Etc…)

Ligninvalorization

Cellulose hydrolysis

IN GREEN CHEMISTRY



Strictly confidential© EURODIA Industrie – 84120 Pertuis - France8 8

Centrifugation,Earth filters , MF/UF

Chemicals : solvants, Acids, BasesIEX / CHROMATOGRAPHY

ED/ BIPOLAR ED / NF

EVAPORATION / CRISTALLIZATION

FERMENTATIONSTEEPING - MILLING

CLARIFICATION : Solids/Liquid

PURIFICATION /EXTRACTION Demin. Deco., pH adjustment,

fractionation

CONCENTRATION



9

INTRODUCTION

R&D

• Laboratory trials

• Pilot trials

• EurodiaPlateform

• Pilots on site

PROCESS

• Processcalculation

• Scale up

• CAPEX/OPEX garanties

ENGINEERING

• PID

• Manufacturing

• Commissionning

• Technicalsupport


Filtration

Ceramic membranes / UF: to optimize DSP

Organic membranes / NF: as part of polishing steps

Ion Exclusion Chromatography

Removal of salts, color, sugars, AA…

Organic acids Fractionation

Ion Exchange Resin systemsConventional systems

Continuous IEX systems

Bipolar Electrodialysis

Conversion of Organic Acids Salts

Industrial references, development of high temperature (65°C) EDBM technology (lower

energy footprint -25%), better control of bacteriological development, processing of viscous

products)

OUR TECHNOLOGIES...



• Multipurpose micro-pilot :– MF, UF, NF with ceramic tubes

: 50 cm2

• MF : 0,2 – 0,5 – 0,8 – 1,4 µm as cut off

• UF : 20 – 50 – 100 nm

• NF : 1000 – 5000 daltons

• UF/NF/R0 pilot with spiral membranes : 2540 - 4040

MEMBRANE FILTRATIONS


• ED pilots :

– feasibility trials with small scale EUR2 pilots 10 cells – 0,2 m2

– Conventional ED :

» EUR2B : 2 cpts

» EUR2C : 3 cpts

» EUR2D : 4 cpts

– Bipolar ED : 2 or 3 cpts

ELECTRODIALYSIS


• Scale up validation with EUR6 pilot :

– 50 cells maxi : 2,8 m2

– Pilot on site : development program with customer. • Small production

• Membrane life time evaluation.

• Batch and Feed & bleed Pilots

• 50 up to 1000 L processing

ELECTRODIALYSIS


• Ion exchange resins :

– Resins evaluation

– Complete ion exchange resins process evaluation

ION EXCHANGE RESINS


• Chromatography :

– Development of new applications

• HPLC chromatogram

• Pulse test with 300 ml resins

• Simulation program – provide mass

• Pulse test with 8 L chromato pilot

• Pilot test with 8 L chromato. Pilot : ISMB – NMCI process

– Validation of application : sampling production

– Resins evaluation

ION EXCLUSION CHROMATOGRAPHY


• Analytical equipment : HPLC Waters Breeze System– Isocratic HPLC Pump : 0.01

mL /min to 10 mL/min– Injector with heater/cooler– Detector refractometer 2414– Column heater compartment– Breeze system as integrator– Column : Shodex SP0810



• Chromatography column :– To handle a pulse test

with a small volume of product :• Column : 1 m length – 26

mm as diameter

• Resin volume : 480 ml

• Product volume : 24 ml

• Flow rate : 240 ml/h

• Sampling : 12 ml

• Temperature : 65°C minimum



• 8 Liters resins ISMB chromatography pilot :

– Pulse test with 450 ml raw product

Table.1 Pulse Test Results

(5)

0

5

10

15

20

25

0,3 0,4 0,5 0,6 0,7 0,8 0,9 1,0

Bed volume ratio

Concentration

BX

Fructose

Glucose

Other



• chromatography pilot :

– 8 columns to simulate 4 /6 ISMB & NMCI (8 liters resins)

– 3 pumps : feed pump –water pump –recirculation pump

– Water bath at right temperature

– Multi-fractions collection



• Validation of separation

– Feed columns with resins + Pulse test : One week

– Optimization of separation : 3 weeks• Take fraction and make

analysis

• Tuning with simulation

• Make a profile

– Raw product volume :• 80 L – 100 L / week



DAIRY INDUSTRY: PRODUCTION OF DWP90

OUR REFERENCES


OUR REFERENCES

STARCH & SUGAR INDUSTRIES: STARCH HYDROLYSATES PURIFICATION


STARCH & SUGAR INDUSTRIES: PURIFICATION OF SUGARS / POLYOLS

OUR REFERENCES


BIOTECH : PRODUCTION OF ORGANIC ACIDS

OUR REFERENCES


Thank you for your

attention!!

www.eurodia.com

© eurodia industrie 84120 pertuis - france strictly ......• analytical equipment : hplc waters...

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