exact cause unknown defect of the skin that impairs its function as a barrier, combined with an...

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INFLAMMATORY SKIN DISORDERS

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Page 1: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

INFLAMMATORY SKIN DISORDERS

Page 2: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

eczema

Page 3: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

pathophysioilogy

exact cause unknown defect of the skin that impairs its function

as a barrier, combined with an abnormal function of the immune system, are believed to be important factors.

Some forms of eczema can be triggered by substances that come in contact with the skin, such as soaps, cosmetics, clothing, detergents, jewelry(contact dermatitis)

Page 4: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

common in infants often have a family history of the

condition or allergic conditions as asthmaor hay fever.(atopy

Page 5: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

Clinical features

Itching Dry reddened skin Blisters/oozing

Page 6: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

sites

Adults/children- insides of the elbows, knees, and ankles.

In infants - face

Page 7: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

management

Steroids –local Antihistamines for itching

Page 8: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

Contact dermatitis

Page 9: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

psoriasis

Psoriasis A chronic inflammatory skin disease

characterized by dry pink scaling round patches.

Cause unknownGenatic and env

Page 10: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

Disorganized

Neutrophilaccumulation

Immaturity

Proliferation

Page 11: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

features

Erythematous, raised patches with silvery scales

Symmetric Pruritic/ Painful Pitting Nails Arthritis in 10-20% of patients Sites-extensor surfaces of knee/elbow

Page 12: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed
Page 13: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed
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Types of psoriasis

Chronic plaque psoriasis Erythrodermic Guttae psoriasis Nail pitting pustular

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Chronic Plaque Psoriasis

Page 16: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

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Erythrodermic Psoriasis

Page 17: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

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Nail changes

Page 18: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

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Guttate Psoriasis

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Page 20: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

management

Difficult to cure Moisturizers Corticosteroids Tar/ vitamin D 3 Drugs for itchinh

Page 21: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

acne

Page 22: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

Causes? Adolecence

Emotional stress Androgens Family history

Page 23: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

Pathogenesis

Plugging of the hair follicle

w/ abnormally keratinized cells

Androgen-induced sebaceous gland hyperactivity

Proliferation of bacteria

Inflammation

Page 24: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

management

Local applications Antibiotics Oral drugs

Page 25: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

urticaria

Page 26: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

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Page 28: exact cause unknown  defect of the skin that impairs its function as a barrier, combined with an abnormal function of the immune system, are believed

Mostly by an allergic reaction Acute urticaria can be treated with

antihistamones

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Thank you!