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Supplementary Materials for

Population transcriptomics of human malaria parasites reveals the

mechanism of artemisinin resistance

Sachel Mok, Elizabeth A. Ashley, Pedro E. Ferreira, Lei Zhu, Zhaoting Lin, Tomas Yeo, Kesinee Chotivanich, Mallika Imwong, Sasithon Pukrittayakamee, Mehul Dhorda, Chea Nguon,

Pharath Lim, Chanaki Amaratunga, Seila Suon, Tran Tinh Hien, Ye Htut, M. Abul Faiz, Marie A. Onyamboko, Mayfong Mayxay, Paul N. Newton, Rupam Tripura, Charles J. Woodrow,

Olivo Miotto, Dominic P. Kwiatkowski, François Nosten, Nicholas P. J. Day, Peter R. Preiser, Nicholas J. White, Arjen M. Dondorp, Rick M. Fairhurst, Zbynek Bozdech*

*Corresponding author. E-mail: [email protected]

Published 11 December 2014 on Science Express DOI: 10.1126/science.1260403

This PDF file includes: Materials and Methods

Figs. S1 to S5

Tables S1 to S3

References

Materials and Methods

In-vivo sample collection

Approximately 10 mL of whole blood were collected from 1,123 patients with falciparum

malaria in a collaborative multi-site study – Tracking Resistance to Artemisinin Collaboration

(TRAC), involving 13 field sites across Southeast Asia (Pailin, Pursat, Preah Vihear and

Ratanakiri in Cambodia; Mae Sot, Srisakhet, Khun Han and Ranong in Thailand; Shwe Kyin in

Myanmar; Binh Phuoc in Vietnam; and Attapeu in Lao PDR), Ramu in Bangladesh and

Kinshasa in DR Congo from 2010 to 2012 (4). After sampling, the patients were treated orally

with artemisinin-based combination therapy (ACT), consisting in part of artesunate at 2 or 4

mg/kg or artemether with lumefantrine as a daily dose for the first 3 days. To determine the

efficacy of artemisinin treatment for each patient, the parasite density was monitored every 2 to 6

hours by microscopy and the parasite clearance measures of half-life, PC50, PC90 and lag-phase

duration were estimated from statistical models using the Parasite Clearance Estimator (PCE)

developed by the WorldWide Antimalarial Resistance Network (WWARN) (31). Patient clinical

data were provided by E. A. Ashley and the TRAC team. Following plasma removal and WBC

depletion using CF11 columns, 0.3 to 0.5 mL of packed red cells from each sample were stored

at 4oC till frozen at -80

oC and then shipped to Nanyang Technological University, Singapore.

Total RNA was isolated from samples using TRIzol® reagent as described (17).

Ex-vivo sample collection

Nineteen of the 91 P. falciparum isolates from patients in Pailin, Western Cambodia, were

cultivated ex vivo for 40 hours as described (17). The parasite densities of these samples ranged

from 13,188 to 161,663 per µL. Briefly, after removing the plasma and buffy coat, whole blood

samples were WBC-depleted using CF11 columns. The resultant infected packed RBCs were

transferred to flasks and cultured in complete medium at 2% hematocrit and 37oC. For each

isolate, 300 µL of packed RBCs were then harvested at 0, 8, 16, 24, 32 and 40 hours. The

parasite clearance half-lives of these 19 isolates ranged from 3.4 to 7.8 hours. “Resistant”

isolates were defined as those with a half-life greater than the median half-life of all 19 isolates.

RNA isolation, cDNA synthesis and microarray hybridizations

For each sample, cDNA was synthesized from 500 ng of total RNA by reverse transcription

followed by 19 cycles of PCR amplification to generate sufficient aminoallyl-coupled cDNA

material for the hybridizations, which were performed as described (17). 4 µg of each CY5-

labelled cDNA patient sample was mixed with an equal amount of CY3-labelled reference pool

consisting of a mixture of P. falciparum 3D7 asexual stages and then hybridized together on our

custom microarray chip using the Agilent hybridization system. Hybridizations were performed

for 20 hours at 65°C in a rotating hybridization oven at 10 rpm. Microarray scanning was done

using PowerScanner (Tecan, Austria) at 10 µM resolution and with automated PMT adjustments

to balance the overall signal intensities in both channels. Data were acquired using GenePix Pro

v6.0 software (Axon Instruments, USA) as described (17).

Microarray data processing and analysis

Microarray data processing with the following quality controls were applied to remove

spurious noise or non-biological variations in intensities. Features with flag >0 and median

foreground intensity >1.5-fold median background intensity for either channel passed quality

control. Local feature background correction using normexp algorithm followed by within-array

Lowess normalization across all features was carried out using R version 2.14 Bioconductor

limma package to generate the normalized log2 expression ratios of the RNA sample/3D7 RNA

reference pool for all probes (32, 33). The gene expression ratio was calculated by averaging the

ratios for all probes that map to the ORF of a gene. The microarray data reported in this

publication have been deposited in NCBI’s Gene Expression Omnibus (GEO) (34) and are

accessible through GEO Series accession number GSE59099

(http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE59099).

Estimation of asexual and gametocyte stage parasites

To estimate the projected asexual parasite age (hpi), Spearman rank correlations to the

previously published in vitro reference transcriptome (35) were used and the best fit correlation

score was taken as the best estimate of parasite age. To estimate relative gametocyte levels for

each isolate, we first defined genes associated with stages III to V of gametocyte development

(36). 121 gametocyte-specific genes were obtained after filtering for genes that were

significantly upregulated in gametocytes compared to asexual stages (corrected P<1e-5) and

with average expression level in gametocyte stages >4-fold higher than the average expression

across the asexual stages (early ring, late ring, early trophozoite, late trophozoite, early schizont

and late schizont taken from Young et al. dataset (36)) and greater than the average expression

across the ring stages (0-18 hpi) of our reference transcriptome (35). With this, we took the mean

log2 expression ratios of the 121 genes as a measure of relative gametocyte proportion for each

isolate.

http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE59099

Statistical analysis and clustering

k-means clustering based on Euclidean distance of all genes was used to cluster the 1,043

isolates into three groups. To calculate associations between clinical variables and parasite

groups, Kruskall-Wallis one-way ANOVA test was applied to test for significance in association.

Mann-Whitney U test was used to test for significance in associations between each paired group

(GrpA vs GrpB, GrpA vs GrpC, GrpB vs GrpC). Linear regression model was applied to obtain a

correlation score and significance value for each gene to parasite clearance half-life. Multiple

testing correction was performed using Benjamini and Hochberg FDR. All statistical tests and

calculations were carried out in R version 2.14. Gene set enrichment analysis (GSEA) (37) was

used to identify differentially expressed functional pathways in two approaches: (i) using the

correlation coefficient scores of gene expression to parasite clearance half-life and (ii) using the

SNR between AR and AS parasites based on a two-group classification of isolates (isolates with

half-life >5 hours were defined as resistant). The nominal P and false discovery rate (FDR)

values were calculated from the normalized enrichment score (NES) using gene set-based

permutations. Gene sets with P <0.05 and FDR<25% were considered to be statistically

significant. Functional enrichment of a subset of genes was analyzed by hypergeometric testing

(P<0.01). P. falciparum gene sets and functional pathways were extracted from Kyoto

Encyclopedia of Genes and Genomes (KEGG) version 2012.05 (38, 39), Gene Ontology

Resource (GO) version 1.3352 (40) and Malaria Parasite Metabolic Pathway (MPM) version 09-

2013 (41). Asexual stage-specific gene sets were defined as the genes which best fitted a sine-

wave curve gene expression profile which is typical for the majority of blood-stage transcripts in

P. falciparum. Hence, 9 model sine curves with peaks at 9 various time points through the IDC

were generated. Microarray data from the published asexual-stage transcriptome (35) were

extracted and filtered for genes showing at least a 3-fold change over the 48-hour IDC. We

classified these stage-specific genes by first calculating the correlation coefficients of the gene’s

expression profile to each of the 9 model curves and then selecting the sine model curve which

gave the maximum correlation coefficient, thereby best reflecting the gene’s expression profile.

The stage assigned to the gene is the intra-erythrocytic developmental stage with peak expression

corresponding to the selected sine model curve. In total, 85 KEGG pathways, 1594 GO gene

sets, 212 MPM pathways and 9 stage-specific gene sets were used in the gene set expression

analysis.

Population structure analysis

Dendrograms were constructed by the neighbor joining method using Pearson correlation

metric of the 5,061 genes across all isolates in each group (GrpA, B and C) using the R version

2.14 phyclust package. Gene markers of field sites were determined based on their significant

differential expression between any 2 field sites in at least 3 pair-wise comparisons (P<1e-5, 1-

way ANOVA). The Euclidean distance metric of these 659 gene expression markers were used

to cluster the Greater Mekong Subregion (excluding Myanmar) isolates of each group. To

identify transcriptionally coherent genes within the Pailin-specific clade, t-test was carried out to

obtain genes significantly differentially expressed between clade and non-clade isolates

(P<0.05). For each clade, the significance of the enrichment of isolates by their field site origin

was determined by hypergeometric testing (P<0.001) and the node with highest percentage of

isolates from the field site was denoted by colored stars.

Construction of ER network

To unveil components of the UPR associated with artemisinin resistance, we analyzed the

relevance of ER gene expression in our dataset within the context of the ER interaction network.

For this purpose, we refined an ER chaperone network based on yeast two-hybrid (19) and

interolog interactions (20) showing the sub-network of highest correlated ER genes and their first

and second neighbors using Cytoscape software (42). Correlation values between gene

expression data and parasite clearance half-life were overlaid on the P. falciparum ER network

and labeled using a green/black/red color gradient from negative positive correlation respectively

with black denoting no correlation (corr(x,y)=0). The node size and font are inversely related to

P<0.05. Dashed grey edges indicates interolog interactions and solid grey lines indicates yeast

two-hybrid derived interactions. For better visualization, nodes of interest were manually

lateralized from the network core.

*** ***

GrpA GrpB GrpC

Proj

ecte

d ho

urs

post

inva

sion

(hpi

)

*** **

Para

site

cle

aran

ce

half-

life

(h)

GrpA GrpB GrpC

****** ***

**

*** ***

PC50

and

PC

90 (h

)

GrpA GrpB GrpC

*** ***

Lag-

phas

e du

ratio

n (h

)

GrpA GrpB GrpC GrpA GrpB GrpC

*** ***

Tem

pera

ture

(oC

)

****** **

Log

as

exua

l pa

rasi

te d

ensi

ty (/

µL)

GrpA GrpB GrpC

10

****

GrpA GrpB GrpCRat

io o

f gam

etoc

yte

to

asex

ual p

aras

ite d

ensi

ties **

GrpA GrpB GrpC

*** ***

Adm

issi

on ti

me

(24-

h cl

ock)

Fig. S1 – Boxplots show clinical and parasitological data from the TRAC study (4), stratified by

group: GrpA, GrpB and GrpC (median - bold horizontal line, box - 25th and 75

th percentiles, the

whiskers - 5th and 95

th percentiles). PC50 and PC90 represent the duration of time for the

reduction of parasitemia by 50% and 90% from initial admission parasite densities respectively.

*P<0.05, **P<0.01, ***P<0.001.

-0.5 0 0.5PCC

048

12Field site

Half-life (h)

GrpA (n=543)

5061

gen

es

Key

Cambodia Thailand Viet-nam

Lao PDR

Myanmar

Bang-ladesh

DR Congo

Pursat Preah Vihear

Rata-nakiri

Pailin MaeSot

Sri-sakhet

KhunHan

Ranong BinhPhuoc

Attapeu ShweKyin

Ramu Kinshasa

P <

0.01

P <

0.01

NESNOM p-val

FDR q-val

LATE RING 2.73 0.00 0.00MID RING 1.53 0.00 0.23RIBOSOME (KEGG-PFA03010) 2.29 0.00 0.00PROTEINS WITH ER RETENTION SEQUENCES (MPM) 2.05 0.00 0.01UNFOLDED PROTEIN BINDING (GO-0051082) 1.84 0.00 0.06PROTEIN FOLDING (GO-0006457) 1.83 0.00 0.06PROTEIN EXPORT (KEGG-PFA03060) 1.77 0.01 0.08

POSTTRANSLATIONAL TRANSLOCATION IN EUKARYOTES (MPM) 1.75 0.00 0.07

SIGNAL RECOGNITION PARTICLE-MEDIATED TARGETING OF MEMBRANE AND SECRETORY PROTEINS (MPM) 1.65 0.02 0.14PROTEASOME (KEGG-PFA03050) 2.05 0.00 0.01PHAGOSOME (KEGG-PFA04145) 1.82 0.00 0.06

PROTEASOME-MEDIATED DEGRADATION OF NON-NATIVE ER PROTEINS (MPM) 1.76 0.00 0.07TRANSLATION (GO-0006412) 1.62 0.00 0.18METHYLTRANSFERASE ACTIVITY (GO-0008168) 1.61 0.01 0.18NUCLEOCYTOPLASMIC TRANSPORT (GO-0006913) 1.85 0.00 0.06CHROMATIN MODIFYING PROTEINS (MPM) 1.52 0.04 0.23REGULATION OF CELL CYCLE (GO-0051726) 1.58 0.03 0.21RNA SPLICING (GO-0008380) 1.56 0.02 0.21

NESNOM p-val

FDR q-val

EARLY SCHIZONT -2.14 0.00 0.01MID SCHIZONT -2.13 0.00 0.00LATE SCHIZONT -1.97 0.00 0.02EARLY RING -1.68 0.00 0.15MID/LATE TROPH -1.66 0.00 0.13MEROZOITES -1.61 0.00 0.15BASE EXCISION REPAIR OF AP SITES (MPM) -1.75 0.00 0.17DNA REPAIR (GO-0006281) -1.73 0.00 0.14DNA MISMATCH REPAIR SYSTEM (MPM) -1.63 0.02 0.14DNA REPLICATION (MPM) -1.68 0.00 0.16FUNCTIONAL ANNOTATION OF MEROZOITE INVASION-RELATED PROTEINS (MPM) -1.69 0.00 0.17REGULATION OF PROTEIN METABOLIC PROCESS (GO-0051246) -1.63 0.03 0.14METHIONINE AND POLYAMINE METABOLISM (MPM) -1.53 0.05 0.20PROTEINS CONTAINING HISTONE POST TRANSLATIONAL MODIFICATION-BINDING MODULES (MPM) -1.63 0.02 0.13LIPID METABOLIC PROCESS (GO-0006629) -1.59 0.02 0.15

*

**

*

*

*

*

B

C

1-1

0

Log 2

ratio

GrpC (n=219)

-0.5 0 0.5PCC

05

1015

Up-regulated gene sets

Down-regulated gene sets

5061

gen

es

Half-life (h)

5061

gen

es

4

6

8

10

Pro

ject

ed h

pi

Kelch WT Kelch MUT

***2.2e-16

Hal

f-life

(h)

468

2

Kelch MUT

1012

Kelch WT

Kelch MUT vs Kelch WT

Field site

Field site

048

12Half-life

(h)



NESNOM p-val

FDR q-val

GAM IV & V 1.78 0.00 0.06LATE RING 2.75 0.00 0.00PROTEINS WITH ER RETENTION SEQUENCES 2.21 0.00 0.00PROTEIN FOLDING (GO-0006457) 1.81 0.00 0.05UNFOLDED PROTEIN BINDING (GO-0051082) 1.77 0.00 0.06PEPTIDYL-PROLYL CIS-TRANS ISOMERASE ACTIVITY (GO-0003755) 1.52 0.05 0.23CHAPERONE-ASSISTED PROTEIN FOLDING (MPM) 1.71 0.00 0.09GENES CODING FOR CHAPERONES AND THEIR REGULATORS (MPM) 1.60 0.00 0.17ENDOPLASMIC RETICULUM (GO-0005783) 1.56 0.01 0.20PROTEIN EXPORT (KEGG-PFA03060) 1.87 0.01 0.03SIGNAL RECOGNITION PARTICLE-MEDIATED TARGETING OF MEMBRANE AND SECRETORY PROTEINS (MPM) 1.55 0.04 0.20RIBOSOME (KEGG-PFA03010) 2.41 0.00 0.00TRANSLATION (GO-0006412) 1.63 0.00 0.15POSTTRANSLATIONAL TRANSLOCATION IN EUKARYOTES (MPM) 1.93 0.00 0.02NUCLEOCYTOPLASMIC TRANSPORT (GO-0006913) 1.62 0.03 0.15RNA SPLICING (GO-0008380) 1.62 0.00 0.15PROTEASOME (KEGG-PFA03050) 2.09 0.00 0.01PROTEASOME-MEDIATED DEGRADATION OF NON-NATIVE ER PROTEINS (MPM) 1.76 0.01 0.06PHAGOSOME (KEGG-PFA04145) 1.88 0.00 0.03METHYLTRANSFERASE ACTIVITY (GO-0008168) 1.81 0.01 0.05REGULATION OF CELL CYCLE (GO-0051726) 1.59 0.03 0.17RAB CYCLE (MPM) 1.52 0.03 0.23

NESNOM p-val

FDR q-val

LATE SCHIZONT -1.94 0.00 0.05MID SCHIZONT -1.93 0.00 0.04EARLY SCHIZONT -1.84 0.00 0.05EARLY RING -2.02 0.00 0.04BASE EXCISION REPAIR OF AP SITES (MPM) -1.90 0.00 0.04DNA REPLICATION (MPM) -1.80 0.01 0.07DNA REPAIR (GO-0006281) -1.53 0.03 0.23NUCLEOTIDYLTRANSFERASE ACTIVITY (GO-0016779) -1.67 0.00 0.12METHIONINE AND POLYAMINE METABOLISM (MPM) -1.67 0.02 0.12FUNCTIONAL ANNOTATION OF MEROZOITE INVASION-RELATED PROTEINS (MPM) -1.88 0.00 0.04FATTY ACID METABOLIC PROCESS (GO-0006631) -1.63 0.03 0.15PROTEINS CONTAINING HISTONE POST TRANSLATIONAL MODIFICATION-BINDING MODULES (MPM) -1.61 0.02 0.17

K13 WT (n=324) K13 MUT (n=145)

NESNOM p-val

FDR q-val

LATE RING 1.77 0.00 0.10PROTEINS WITH ER RETENTION SEQUENCES (MPM) 2.07 0.00 0.06ENDOPLASMIC RETICULUM (GO-0005783) 1.76 0.00 0.09POSTTRANSLATIONAL TRANSLOCATION IN EUKARYOTES (MPM) 1.90 0.00 0.05PROTEIN TRANSPORTER ACTIVITY (GO-0008565) 1.99 0.00 0.05PHAGOSOME (KEGG-PFA04145) 1.94 0.00 0.05PROTEASOME (KEGG-PFA03050) 1.50 0.04 0.28ENDOPEPTIDASE ACTIVITY (GO-0004175) 1.62 0.02 0.16NUCLEOCYTOPLASMIC TRANSPORT (GO-0006913) 1.61 0.03 0.17IMPORT AND EXPORT THROUGH THE NUCLEAR PORE (MPM) 1.83 0.01 0.07KARYOPHERIN OR EXPORTIN-MEDIATED NUCLEAR EXPORT PATHWAYS (MPM) 1.64 0.02 0.16METHYLTRANSFERASE ACTIVITY (GO-0008168) 1.63 0.03 0.16

NESNOM p-val

FDR q-val

EARLY RING -1.94 0.00 0.08PROTEINS CONTAINING HISTONE POST TRANSLATIONAL MODIFICATION-BINDING MODULES (MPM) -1.94 0.00 0.04

A



Fig. S2 – Heat maps of the mean-centered log2 gene expression ratios of 5,061 genes and

functional biological pathways found to be significantly (P<0.05 and FDR<25%) associated with

(A) parasite clearance half-life for GrpA isolates (n=543), (B) the mutant K13 allele genotype

linked with artemisinin resistance in GrpA isolates and (C) parasite clearance half-life for GrpC

isolates (n=222). Isolates are ordered by increasing parasite clearance half-life (top grey bars in

(A) and (C)). The upper colored bars indicate the geographical origin of each isolate. The genes

in the heat map are ordered according to the Pearson correlation coefficient (PCC) obtained from

the regression analyses as shown in grey bar graph at the right of heat maps of (A) and (C). Red

asterisks mark gene sets which are significantly up-regulated in GrpA, GrpC and isolates

harboring K13-propeller mutations. The GSEA parameters include: normalized enrichment score

(NES), nominal P value (NOM p-val) and false discovery rate (FDR q-val).

Plasmodium Reactive Oxidative Stress Complex (PROSC)

TCP-1 Ring Complex (TRiC)

0.35

-0.30

High exp. in AR

0.00

Correlation to half-life

Low exp. in AR

P < 0.01

0.01 ≤ P ≤ 0.05

P > 0.05 (NS)

Scale:

Key:

Fig. S3 - Interaction network of genes involved in protein chaperone-like activities tin the P.

falciparum genome. The nodes (genes) are colored based on correlation between expression and

clearance half-life: red- positive; green- negative. Node size is reflects significance (P value) of

the correlation (see scale); dashed lines- interolog interactions and solid lines- yeast two-hybrid

derived interactions.

KH004-077

KH004-073

KH004-090

KH004-096

KH004-076

KH004-072

KH004-094

KH004-086

KH004-075

KH004-100

KH004-071

KH004-093

KH004-068

KH004-080

KH004-089

KH004-082

KH004-074

KH004-098

KH004-070

4909

gen

es

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 40

8h interval

0 32

* *time point sample not harvested*

Patient code:

Sampling time:

Log2 ratio-1.5 -1.0 -0.5 0 0.5 1.0 1.5

Fig. S4 – Heat map of the mean-centered log2 gene expression ratios of 4,909 genes in 19 P.

falciparum isolates from Pailin, Western Cambodia, which were sampled directly from malaria-

infected patients at 0 hours, and after ex-vivo cultivation for 8, 16, 24, 32 and 40 hours. Genes

are ordered according to the phase calculated by the Fast Fourier Transformation of the reference

in vitro IDC transcriptome.

BD001−004

BD001−014

BD001−015

BD001−017

BD001−021

BD001−022

BD001−023

BD001−028 BD

001−032

BD001−037

BD001−038

BD001−040

BD001−043

BD001−045

BD001−047

BD001−049

BD001−050

BD001

−051

BD001−

052

BD001−053

BD001−

055

CD001−001

CD001−002

CD001−005

CD001−008

CD001−011CD001−012

CD001−014

CD001−015

CD001−019

CD001−023C

D001−028

CD001−029

CD001−033

CD001−044

CD001−049

CD001−054

CD001−056CD001−057

CD001−058

CD001−063

CD001−065

CD001−068

CD001−069

CD001−070

CD001−073CD001−074

CD001−075

CD001−077

CD001−079

CD001−080

CD001−081

CD001−085

CD001−086

CD001−089

CD001−090

CD001−093

CD001−094

CD001−095

CD001−097

CD001−100

CD001−101

CD001−104

CD001−105

CD001−106

CD001−107

CD001−117

CD001−118

CD001−119

CD001−120

KH001−001

KH001

−004KH00

1−005

KH001−006

KH001−007

KH001−012

KH001−01

5

KH001

−016

KH001−017

KH001−020

KH001−021

KH001−023

KH001−02

4

KH001−025

KH001−02

8

KH001−029

KH001−030KH001−031

KH001−

034KH

001−03

8

KH001−039

KH001−040

640−

100

HK

740−

100

HK

KH001−051

KH001−055

KH001−059

KH001−060

KH001−062

KH001−063

KH001−064

KH001−0

66

KH001−069

KH001−070

KH001−073

KH001−0

76

KH001−078

KH001−081

KH001−082

KH001

−083

KH001−0

86

KH001−088

KH001

−091

KH001−092

KH001−093

KH001

−098

KH001−099

KH001−100

KH001−106

KH001−1

07

KH001−

112

KH002

−003

KH002−0

05

KH002−010 KH

002−011

KH002−012KH002−013

KH002−

014KH002−016

KH002−017

KH002−018

KH002−019

KH002−020

KH002−021

KH002−022

KH002−023

KH002

−025

KH002−027

KH002−029

KH002

−030

KH002−032

KH002−033

KH002−038

KH002−

041

KH002−042

KH002−044

KH002−045

KH002−046

KH002−047

KH002−048

KH002−049

KH002−050

KH002−051

KH002

−052

KH002−053

KH002−054

KH002−055

KH002−057

KH002−059

KH002−060

KH002−061

KH002

−062

KH002−064

KH002−067

KH002−068

KH002−070

KH002−0

71

KH002−075

970−

200

HK

KH002−081

KH002−082

KH002−083

KH002−085

KH002−086

KH002−087

KH002−088

KH002−089

KH002−090KH002−091

KH002−092

KH002−093

KH002−094

KH002−097

KH002−098

KH002−100 KH

002−101

KH002−102

KH002−105

KH002−107

KH002−108KH002−110

KH002−111

KH002−112

KH002−114

KH002−115

KH002−116

KH002−117

KH002−120

KH003−009

010−300H

K

KH003−012

KH003−0

13

KH003−019

KH003−020

KH003−021

KH003−022

KH003−024

KH003−025

KH003−027

KH003−029

KH003−030

KH003−031

KH003−032

KH003−034

KH003−035

KH003−036

KH003−037

KH003−

038KH003−040

KH003−041

KH003−042

KH003−044

KH003−046

KH003−047

KH003−048

KH003−049

KH003−05

1

KH003−052

KH003−054

KH003−058

KH003−060

KH003−

061

KH003

−063

KH003−064

KH003−067

KH003−0

68

KH003−0

72

KH003−

073

KH003−074

KH003−077

KH003−078

KH003−081

KH003−082

KH003−084

KH003−089

KH003−091

KH003−099

KH003−101

KH003−102

KH003−103

KH003−104

KH003−109

KH003−110

KH003−111

KH003−114

KH003−115

KH004−001

KH004−002

KH004−007

KH004−008

KH004

−012

KH004−013

KH004−014

KH004

−015

KH004−

018

KH004−019

KH004−021

KH004−024

KH004−025

KH004−027

KH004−028

KH004−030

KH004−031

KH004−032KH004−03

3KH004−034

KH004−036KH004−037

KH004−038KH004−039KH00

4−040

KH004−042

KH004−045

KH004−047KH004

−048 KH004−049

KH004−

051

KH004−053

KH004−055

KH004−

056

KH004−058

KH004−060

KH004−064

KH004−066

KH004−

067

KH004−068

KH004

−070

KH004−074

KH004−079

KH004−080

KH004−082

KH004−083

480−

400

HK

KH004−084

KH004−086

KH004−089

KH004−091

KH004−093

KH004−095

KH004−096

KH004−097

KH004−098

KH004−099

KH004−100

LA001−001

LA001−003

LA001−

004

LA001−00

8LA00

1−010

LA001−011

LA001−016

LA001−018

LA001−022

LA001−023

LA001−024

LA001−038

LA001−042

LA001−044

LA001−045

LA001−046

LA001−047

LA001−049

LA001−050

LA001−051

LA001−064

LA001−070

LA001−072

LA001−076

LA001−077

LA001−078

LA001−082

LA001

−085

LA001−094

LA001−095

LA001−096

LA001−098

LA001

−099

LA001−101

LA001−107

LA001−108

LA001−112

LA001−116

LA001−119

LA001−120

MM001−001

MM001

−002

MM001−003MM001−004

MM001−005

MM001−005

MM001−006

MM001−006

MM001

−007

800−100M

M

MM001−010

MM001−011

MM001−013

MM001−014

MM001−015

MM001−016

MM001−017

MM001−019

MM001−020 M

M001−021

MM001−022

MM001−024

MM001−026

820−100M

M

MM001−029

MM001−030 430−100

MM

MM001−037 M

M001−038

MM001−041

MM001−042

MM001−045

MM001−047

MM001−049

MM001−050

MM001−052

350−

100

MM 450−100

MMM

M001−062

MM001−063

MM001−064

MM001−065 MM001−066

MM001−067

MM001−070

MM001−071

MM001−074

MM001−077

MM001−078

TH004−

002

TH004−003

TH004−010

TH004−012

TH004

−014

TH004−015

TH004−020

TH004−022TH

004−024

TH004−

025

TH004−026

TH004−029

TH004−029

TH004

−031

TH004−038

TH004−047

TH004−050

TH004−052

TH004−053

TH004−058

TH004−061

TH004−062

TH004−064

TH004−065

TH004−068

TH004−069

TH004−072

TH004−074

TH004−077

TH004−079

TH004−086

TH004−088

TH004−088

TH004−090

TH004−092

TH004−093

TH004−094

TH004−095

TH004−09

6

TH004−097

TH004−099

TH004−107

TH004−108

TH004−110

TH004−111

TH004−112

TH004−115

TH004−116

711−400HT

TH004−118

TH004−120

TH005−003

TH005−006

TH005−007

TH005−008

TH005−009

TH005−011

TH005−012

TH005−013

TH005−015

TH005−026

TH006−002

TH006−007

900−

600

HT

TH006−010

TH007−001

TH007−002

TH007−005

TH007−006

TH007

−007

TH007

−008

TH007−009

TH007−011

TH007−012

TH007−013

TH007−015

TH007−018

TH007−019TH

007−020

TH007−023

VN001−001 VN001−006

VN001−007

VN001−008

VN001−009

VN001−011 VN001−013

VN001−014

VN001−016

VN001−018

VN001−021

VN001−025

VN001−027

VN001−028VN001−029

VN001−030

VN001−033

VN001−036

VN001−037

VN001−038

VN001−039

VN001−040

VN001−041

VN001−042

VN001−045

VN001−047

VN001−048

VN001−049

VN001−051

VN001−053

VN001−056

VN001−059

VN001−06

0

VN001−062

VN001−063

VN001−064

VN001−066

VN001−068

VN001−072

VN001−076

VN001−077

VN001−078

VN001−079

VN001−085

VN001−087

VN001−088VN001

−092

VN001

−093

VN001−094

VN001−096

VN001−097

VN001−098

VN001−101VN001−102

VN001−103

VN001−105

VN001−107

VN001−108

VN001−109

VN001−110

VN001−111

VN001−112

VN001−113VN001−114

VN001−115

VN001−120

BD001−018

BD001−024

BD001−029

BD001−034

CD001−003

CD001−017

CD001−018

CD001−021

CD001−027

CD001−036

CD001−037

CD001−038

CD001−039

CD001−040

CD001−041 C

D001−046

CD001−050

CD001−051

CD001−053

CD001−076

CD001−091

CD001−099

CD001−116

KH001−011

KH001−013KH001−018

KH001−026

KH001−032

KH001−036

KH001−041

KH001−043

KH001−048

KH001−049

KH001−057

KH001−058

KH001−061

KH001−068

KH001−072

KH001−074

KH001−075

KH001−084

KH001−089

090−100 HK

KH001−094

KH001−095

KH001−096

KH001−101

KH001−102

KH001−104

KH001−105

KH001−108

KH001−109

KH001−110

KH001−113

KH001−116KH001−117

KH001−118

KH001−120

KH002−002

KH002−006

KH002−008

KH002−009

510−200HK

KH002−031

KH002−035

KH002−037

KH002−072

KH002−073

KH002−076

KH002−077

KH002−095

KH002−096

KH002−103KH

002−119

KH003−004

KH003−011

KH003−016

KH003−033

KH003−043

KH003−053

KH003−055

KH003−066

KH003−069

KH003−080

KH003−085

KH003−088KH003−090

KH003−096

KH003−097

KH003−100

KH003−105

KH003−112

KH003−113

KH003−118KH003−119

KH003−120

KH004−005

KH004−022

KH004−035

KH004−044

KH004−052

KH004−054

KH004−059

160−400 HK

KH004−062

KH004−073

KH004−073

KH004−075 KH004−076

KH004−077

KH004−078

KH004−081

KH004−085

KH004−092

KH004−094

LA001−020

LA001−034

LA001−052

LA001−063

LA001−066

LA001−068

LA001−071

LA001−074

LA001−079LA001−080

LA001−081

LA001−083

LA001−084

LA001−091

LA001−092

LA001−100

LA001−102LA001−103

LA001−105

LA001−106

LA001−110

LA001−113

LA001−115

LA001−117

LA001−118

MM001−012

MM001−018

MM001−025

MM001−032MM001−035

MM001−036

MM001−043

MM001−046

MM001−048

MM001−051

MM001−057

MM001−059

MM001−069

MM001−072

MM001−075

TH004−004

TH004−006

TH004−013

TH004−019

TH004−021

TH004−023

TH004−032

TH004−040

TH004−041

TH004−054

TH004−057TH004−059

TH004−060

760−400HT TH004−076

TH004−084

TH004−086

TH004−089

TH004−089

TH004−101

TH004−106

TH004−113

TH005−004

TH005−010

TH005−017

TH005−018

TH005−021

TH005−022

TH005−023

TH005−024

TH005−025

TH005−027TH005−028

TH005−029

TH006−004

TH006−006

TH006−011

TH006−012

TH007−003

TH007−021

VN001−003

VN001−012

VN001−015

VN001−017

VN001−019

VN001−022

VN001−024

VN001−026

VN001−031

VN001−034

VN001−035

VN001−050

VN001−052

VN001−058

VN001−061

VN001−067

VN001−073

VN001−074

VN001−075VN001−081

VN001−086

VN001−089VN001−095

VN001−104

VN001−117

VN001−118

VN001−119

BD001−001

BD001−002

BD001−003

BD001−005

BD001−006

BD001−007

BD001−008

BD001−009

BD001−010

BD001−012

BD001−016

BD001−019

BD001−020

BD001−025

BD001−026

BD001−027

BD001−030

BD001−033 BD

001−035

BD001−036

BD001−039

BD001−041

BD001−042

BD001−044

BD001−046

BD001−048

BD001−054

BD001−056

CD001−004

CD001−006

CD001

−007

CD001−009

CD001−01

0

CD001−01

3

CD001−016

CD001−024

CD001−025

CD001−026

CD001−030

CD001−031

CD001−032

CD001−034

CD001−0

35

CD001−042

CD001−0

45

CD001−

047

CD001−052

CD001−055

CD001

−059

CD001−

061

CD001−062

CD001−064

CD001−066

CD001−071

CD001−072

CD001−078

CD001−

082

CD001−083

CD001−084

CD001−087

CD001−088

CD001−092

690−100 DC

CD001

−098

CD001−102

CD001−103

CD001−108

CD001−109

CD001−110

CD001−111

CD001−112

CD001−113

CD001

−114

CD001−115

KH001−022

KH001−044

KH001−052

KH001−054

KH001−056

KH001−065

KH001

−067KH001−

071

KH001−077

KH001−0

79

KH001

−080

KH001−087

KH001−097

KH001−103

KH001−111

KH001−114

KH001−119

KH002

−001

KH002−007

KH002−024

KH002−02

8

KH002−034

KH002−036

KH002−039

KH002−040

KH002−043

KH002−056

KH002−058

KH002−063

KH002−065

KH002−066

KH002−069

KH002−074

KH002−078

KH002−084

KH002

−099

KH002

−104

KH002−106

KH002−109

KH002−118

KH003−015

KH003−017

KH003−018

KH003−028

KH003−039

KH003−045

KH003−050

KH003−056

KH003−057

KH003−059

KH003−065

KH003−070

KH003−071

KH003−075

KH003−076

KH003−079

KH003−083

KH003−086

KH003−087

KH003−092

KH003−094

KH003−095

KH003−098

KH003−107

KH003−116

KH003−117

KH004−

016KH004−

020

KH004−023

KH004

−041

KH004−043

KH004−

046

KH004−057

KH004−063

KH004−065

KH004−069

KH004−071

KH004−087

KH004−088

KH004−090

LA001

−002

LA001

−005 LA

001−006

LA001−007

LA001−

009

LA001−012

LA001−013 LA

001−015LA0

01−019

LA001−041

LA001−04

3

LA001−062

LA001−

065

LA001−069 LA

001−073

LA001−075

LA001−086

LA001−

093

LA001−097

LA001−109

LA001−111

LA001−114

MM001−0

09

MM001−0

23

MM001−027

MM001−031

MM001−033

MM001−039

MM001−040

MM001−044

MM001−055

MM001−056MM001−058

MM001−060

MM001−061

MM001−068

MM001−073

670−100MMMM001−079

MM001−080

TH004−001

TH004−005

TH004−007

TH004−008

TH004−009

TH004−011

TH004−016

TH004−017

TH004

−018

TH004−027

TH004−028

TH004−028

TH004−030

TH004−033 TH004−034

TH004−

035

TH004

−036

TH004−037

TH004−

039

TH004−

042

TH004−044

TH004−046

TH004−

048

TH004−049

TH004−051

TH004

−055

TH004−056

TH004−063

TH004

−066

TH004−070

TH004−071

TH004−073

TH004−075

TH004

−078

TH004−080

TH004−081

TH004−082

TH004−083

TH004−085

TH004−087

TH004−087

TH004−091

TH004−098

TH004−102

TH004−103

TH004−104

TH004−105

TH004−114

TH005−001

TH005−002

TH005−0

05

TH005−014

TH005−020

TH006−003

TH007−00

4

TH007−0

10

TH007−014

TH007−016

VN001

−002

VN001−004

VN001

−005

VN001

−010

320−100 NV

VN001−032

VN001−

046

VN001

−054

VN001−

055

VN001−

057 VN001−

069

VN001−070

VN001−08

0

VN001−082

480−100NV

VN001−091

VN001−0

99

VN001−100

VN001−106

VN001−116

GrpB (n=272) GrpC (n=222)

BangladeshDR Congo

MyanmarGreater Mekong Subregion (excluding Myanmar)

GrpA (n=549)

Fig. S5 – Cladogram of the 549 GrpA, 272 GrpB and 222 GrpC field isolates clustered by

Pearson correlations of the transcriptomes and colored by their geographic origin (see color key).

Header DescriptionPatient Code Patient code number of sampleBarcode Barcode number of sampleCountry Country where sample was collectedField site Name of field site where sample was collectedField site Code Code assigned to field site codeField site color Color assigned to field sitepRBC sampling vol. (uL) Volume of packed RBC collected (uL)Gender M: Male; F: FemalePatient age (yr) Age of patient in yearsHb (g/dL) Hemoglobin level (g/dL) of the full blood count on admissionHct (%) Patient hematocrit (%) on admissionasexual parasite count Total asexual parasite densities per uL on admissiongam. count Total gametocyte parasite densities per uL on admissiontotal parasite count Total parasite densities (asexual and gametocyte) per uL on admissionratio of gam:total parasite Ratio of gametocyte to total parasite densitieslog2 ratio of gam:total parasite Log2 transformed ratio of the gametocyte to total parasite densitiesTotal parasite in sample (X 1000) Total number of parasites in whole sample of infected RBC collected (pRBC collection vol. * total parasite count per uL) divided by 1000Sampling Time (24-hr) Time of sample collection in 24 hour formatPatient temp. (oC) Patient temperature at sample collection time (degrees celsius)ART drug Type and dosage of artemisinin drug given once a day on days 0, 1 and 2; AS: Artesunate; AL: Artemether+Lumefantrine; AS2: 2mg/kg; AS4: 4mg/kg daily dose

ACT partner drug Partner drug (Artemisinin based combination treatment) administered from day 3 onwards; "+": 2 drugs taken together at each dose; "/": either drug taken at alternate intervals)

parasite clearance halflife (h) Estimated time in hours it takes for parasitaemia to decrease by half measured from the slope of the log-linear clearance curve which is independent of the starting parasitemia level

Tlag (h) Duration of lag phase in hoursClearance rate constant Estimated clearance rate constant (K) (1/hours); Calculated by the minus slope of the final loge model after exclusion of outliers, lag phase and tail.SE of clearance Standard error of clearance rate constantIntercept of tlag Intercept at time = Tlag

R2 R2 statistic from the linear (or tobit) regression on datapoints used to estimate clearance (i.e. lag phase and tail are excluded) and excluding measurements below the level of detection.

PC50 (h) Estimated time in hours it takes for parasitaemia to reduce by 50% of its initial admission valuePC90 (h) Estimated time in hours it takes for parasitaemia to reduce by 90% of its initial admission valuePC95 (h) Estimated time in hours it takes for parasitaemia to reduce by 95% of its initial admission valuePC99 (h) Estimated time in hours it takes for parasitaemia to reduce by 99% of its initial admission valueRNA yield (ug) Amount of Total RNA isolated for each sample (µg)Asexual stage (hpi) Projected hours post invasion (hpi) of the parasite asexual stageSRCC asexual stage Spearman rank correlation coefficient of the gene expression for the isolate sample to the projected hpimean gam. exp ratio Average gene expression ratio of the 121 gametocyte specific genes for the isolate sampleKmeans Grp K means clustered group A, B or CGrpA subtype Subgrouping of GrpA isolates based on NJ tree; 1: South east asian isolates; 2: othersGrpB subtype Subgrouping of GrpB isolates based on NJ tree; 1: South east asian isolates; 2: othersGrpC subtype Subgrouping of GrpC isolates based on NJ tree; 1: South east asian isolates; 2: others

K13 (KP/BTB) Genotypes from Olivio Miotto: 0=missing (i.e. less than 5 sequencing reads at that position); 1=reference allele (same as 3D7); 2=mutant allele (Kelch13 mutation in any propellar domain); 3=heterozygous (i.e. at least 2 reads for each of the two alleles); "NA"=no sequence data available

crt-N326S Genotypes from Olivio Miotto: 0=missing (i.e. less than 5 sequencing reads at that position); 1=reference allele (same as 3D7); 2=mutant allele (row 1 for resulting mutation); 3=heterozygous (i.e. at least 2 reads for each of the two alleles); "NA"=no sequence data available

crt-I356T Genotypes from Olivio Miotto: 0=missing (i.e. less than 5 sequencing reads at that position); 1=reference allele (same as 3D7); 2=mutant allele (row 1 for resulting mutation); 3=heterozygous (i.e. at least 2 reads for each of the two alleles); "NA"=no sequence data available

fd-D193Y Genotypes from Olivio Miotto: 0=missing (i.e. less than 5 sequencing reads at that position); 1=reference allele (same as 3D7); 2=mutant allele (row 1 for resulting mutation); 3=heterozygous (i.e. at least 2 reads for each of the two alleles); "NA"=no sequence data available

mdr2-T484I Genotypes from Olivio Miotto: 0=missing (i.e. less than 5 sequencing reads at that position); 1=reference allele (same as 3D7); 2=mutant allele (row 1 for resulting mutation); 3=heterozygous (i.e. at least 2 reads for each of the two alleles); "NA"=no sequence data available

Note: "NA" data not available

Table S1. Parasitological and clinical data for the 1,043 P. falciparum isolates analzyed in this study. Description of headers below.

Patient Code Barcode Country Field site Field site Code

Field site

color

pRBC sampling vol. (uL)

Gender Patient age (yr)

Hb (g/dL) Hct (%)

asexual parasite count

gam. count

total parasite count

BD001-001 219888 Bangladesh Ramu BD 300 M 14 NA 36 18086 0 18086BD001-002 219908 Bangladesh Ramu BD 500 M 42 NA 46 23110 0 23110BD001-003 219688 Bangladesh Ramu BD 500 M 30 NA 47 35419 0 35419BD001-004 219590 Bangladesh Ramu BD 500 F 10 NA 35 224196 0 224196BD001-005 219618 Bangladesh Ramu BD 500 M 27 NA 45 16956 0 16956BD001-006 219616 Bangladesh Ramu BD 500 M 19 NA 40 10048 0 10048BD001-007 189420 Bangladesh Ramu BD 300 M 16 NA 44 71843 0 71843BD001-008 189436 Bangladesh Ramu BD 500 M 40 NA 42 63302 0 63302BD001-009 189449 Bangladesh Ramu BD 500 M 50 NA 41 51496 0 51496BD001-010 189463 Bangladesh Ramu BD 500 M 21 NA 45 56520 0 56520BD001-012 189491 Bangladesh Ramu BD 500 M 20 NA 40 15072 0 15072BD001-014 219784 Bangladesh Ramu BD 500 F 30 NA 40 40192 0 40192BD001-015 219800 Bangladesh Ramu BD 500 M 22 NA 38 33410 0 33410BD001-016 189526 Bangladesh Ramu BD 500 M 40 NA 43 16202 0 16202BD001-017 189534 Bangladesh Ramu BD 500 M 35 NA 43 21603 0 21603BD001-018 189577 Bangladesh Ramu BD 500 M 27 NA 43 48607 0 48607BD001-019 219820 Bangladesh Ramu BD 500 M 19 NA 48 174835 0 174835BD001-020 219948 Bangladesh Ramu BD 300 M 12 NA 36 27130 0 27130BD001-021 219971 Bangladesh Ramu BD 500 M 51 NA 41 10299 0 10299BD001-022 189595 Bangladesh Ramu BD 500 M 19 NA 42 15826 0 15826BD001-023 231053 Bangladesh Ramu BD 300 M 14 NA 40 45216 0 45216BD001-024 230956 Bangladesh Ramu BD 300 F 13 NA 32 32154 0 32154BD001-025 231059 Bangladesh Ramu BD 500 F 21 NA 43 129619 0 129619BD001-026 231062 Bangladesh Ramu BD 500 M 50 NA 35 26376 0 26376BD001-027 230975 Bangladesh Ramu BD 500 M 27 NA 39 19594 0 19594BD001-028 230993 Bangladesh Ramu BD 500 M 26 NA 39 19594 0 19594BD001-029 231004 Bangladesh Ramu BD 500 M 25 NA 33 20724 0 20724BD001-030 231011 Bangladesh Ramu BD 500 M 26 NA 40 15072 0 15072BD001-032 231035 Bangladesh Ramu BD 500 M 30 NA 44 55264 0 55264BD001-033 231074 Bangladesh Ramu BD 500 M 26 NA 40 10048 0 10048BD001-034 231080 Bangladesh Ramu BD 500 M 20 NA 47 17710 0 17710BD001-035 231101 Bangladesh Ramu BD 500 M 40 NA 36 22608 0 22608BD001-036 231099 Bangladesh Ramu BD 500 M 55 NA 43 27004 0 27004BD001-037 231116 Bangladesh Ramu BD 500 M 30 NA 48 54259 0 54259BD001-038 231134 Bangladesh Ramu BD 300 F 11 NA 39 48984 0 48984BD001-039 231141 Bangladesh Ramu BD 500 M 40 NA 44 49738 0 49738BD001-040 219844 Bangladesh Ramu BD 500 F 27 NA 43 167425 0 167425

Table S1. Parasitological and clinical data for the 1,043 P. falciparum isolates analzyed in this study. Description of headers are in "description" sheet. Data not available are indicated by "NA".

Page 1 of 135


Field site

color



Hb (g/dL) Hct (%)


gam. count


BD001-041 219855 Bangladesh Ramu BD 500 M 25 NA 41 77244 0 77244BD001-042 219866 Bangladesh Ramu BD 500 M 30 NA 40 15072 0 15072BD001-043 231148 Bangladesh Ramu BD 300 F 15 NA 33 41448 0 41448BD001-044 230854 Bangladesh Ramu BD 500 M 22 NA 44 16579 0 16579BD001-045 230866 Bangladesh Ramu BD 300 M 14 NA 35 13188 0 13188BD001-046 230757 Bangladesh Ramu BD 500 M 30 NA 43 27004 0 27004BD001-047 230771 Bangladesh Ramu BD 300 M 11 NA 32 60288 0 60288BD001-048 230779 Bangladesh Ramu BD 500 M 30 NA 42 26376 0 26376BD001-049 230793 Bangladesh Ramu BD 500 M 23 NA 37 32530 0 32530BD001-050 230803 Bangladesh Ramu BD 500 M 50 NA 33 12434 0 12434BD001-051 230816 Bangladesh Ramu BD 300 M 16 NA 40 10048 0 10048BD001-052 230828 Bangladesh Ramu BD 300 M 17 NA 39 24492 0 24492BD001-053 231162 Bangladesh Ramu BD 500 M 47 NA 36 49738 0 49738BD001-054 231175 Bangladesh Ramu BD 500 M 35 NA 46 11555 0 11555BD001-055 230877 Bangladesh Ramu BD 500 M 28 NA 45 50868 0 50868BD001-056 230889 Bangladesh Ramu BD 500 M 26 NA 42 47477 0 47477CD001-001 211757 DRCongo Kinshasa CD 300 F 4 NA 25 109900 0 109900CD001-002 211756 DRCongo Kinshasa CD 300 F 4 NA 25 266900 0 266900CD001-003 211782 DRCongo Kinshasa CD 300 F 1 NA 33 20724 0 20724CD001-004 211784 DRCongo Kinshasa CD 300 M 4 NA 29 40066 64 40130CD001-005 211786 DRCongo Kinshasa CD 300 M 1 NA 26 16328 0 16328CD001-006 211802 DRCongo Kinshasa CD 300 F 6 NA 30 22608 16 22624CD001-007 211818 DRCongo Kinshasa CD 300 M 5 NA 33 111910 0 111910CD001-008 NO BC DRCongo Kinshasa CD 300 M 5 NA 42 216283 0 216283CD001-009 211833 DRCongo Kinshasa CD 300 M 4 NA 29 91060 0 91060CD001-010 211449 DRCongo Kinshasa CD 300 M 8 NA 28 168806 0 168806CD001-011 211469 DRCongo Kinshasa CD 300 F 2 NA 30 109272 0 109272CD001-012 211468 DRCongo Kinshasa CD 300 F 5 NA 31.5 605329 0 605329CD001-013 211483 DRCongo Kinshasa CD 300 M 0.7616438 NA 31 62298 0 62298CD001-014 211499 DRCongo Kinshasa CD 300 F 8 NA 33 41448 0 41448CD001-015 211503 DRCongo Kinshasa CD 300 M 7 NA 28 341130 0 341130CD001-016 211532 DRCongo Kinshasa CD 300 F 7 NA 30 18840 32 18872CD001-017 211536 DRCongo Kinshasa CD 300 F 3 NA 25 40820 0 40820CD001-018 211539 DRCongo Kinshasa CD 300 M 5 NA 29 58278 16 58294CD001-019 211257 DRCongo Kinshasa CD 300 F 4 NA 31 101234 0 101234CD001-021 231856 DRCongo Kinshasa CD 300 F 2 NA 23 11555 32 11587CD001-023 231888 DRCongo Kinshasa CD 300 F 3 NA 18 131126 16 131142CD001-024 231887 DRCongo Kinshasa CD 300 M 5 NA 34 68326 48 68374CD001-025 211671 DRCongo Kinshasa CD 300 F 2 NA 25 62800 0 62800CD001-026 211673 DRCongo Kinshasa CD 300 F 7 NA 24 27130 0 27130

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Hb (g/dL) Hct (%)


gam. count


CD001-027 211711 DRCongo Kinshasa CD 300 M 3 NA 30 52752 0 52752CD001-028 211712 DRCongo Kinshasa CD 300 F 5 NA 31 31149 16 31165CD001-029 211713 DRCongo Kinshasa CD 300 M 5 NA 34 217790 0 217790CD001-030 NO BC DRCongo Kinshasa CD 300 M 8 NA 30 22608 48 22656CD001-031 NO BC DRCongo Kinshasa CD 300 M 4 NA 32 12058 0 12058CD001-032 NO BC DRCongo Kinshasa CD 300 M 3 NA 26 16328 0 16328CD001-033 NO BC DRCongo Kinshasa CD 300 F 8 NA 33 107765 0 107765CD001-034 NO BC DRCongo Kinshasa CD 300 F 4 NA 33 58027 0 58027CD001-035 NO BC DRCongo Kinshasa CD 300 M 7 NA 35 26376 272 26648CD001-036 NO BC DRCongo Kinshasa CD 300 M 5 NA 30 162024 880 162904CD001-037 228679 DRCongo Kinshasa CD 300 M 5 NA 24 33158 304 33462CD001-038 228680 DRCongo Kinshasa CD 300 F 2 NA 24 42202 0 42202CD001-039 228741 DRCongo Kinshasa CD 300 F 7 NA 31 42830 0 42830CD001-040 228578 DRCongo Kinshasa CD 300 F 5 NA 27 54259 0 54259CD001-041 228580 DRCongo Kinshasa CD 300 F 1 NA 34 17082 16 17098CD001-042 228608 DRCongo Kinshasa CD 300 M 0.9479452 NA 29 25497 0 25497CD001-044 228657 DRCongo Kinshasa CD 300 F 8 NA 30 22608 0 22608CD001-045 228658 DRCongo Kinshasa CD 300 M 1 NA 26 104499 32 104531CD001-046 228659 DRCongo Kinshasa CD 300 M 2 NA 26 84906 0 84906CD001-047 228905 DRCongo Kinshasa CD 500 M 2 NA 34 68326 0 68326CD001-049 228560 DRCongo Kinshasa CD 300 F 8 NA 36 27130 16 27146CD001-050 228561 DRCongo Kinshasa CD 300 M 5 NA 33 24869 16 24885CD001-051 228562 DRCongo Kinshasa CD 300 F 2 NA 36 27130 0 27130CD001-052 228907 DRCongo Kinshasa CD 300 M 8 NA 33 16579 0 16579CD001-053 228938 DRCongo Kinshasa CD 300 F 4 NA 27 40694 16 40710CD001-054 228964 DRCongo Kinshasa CD 300 F 6 NA 33 157502 0 157502CD001-055 228963 DRCongo Kinshasa CD 300 M 2 NA 34 85408 64 85472CD001-056 253768 DRCongo Kinshasa CD 300 F 3 NA 35 61544 0 61544CD001-057 253769 DRCongo Kinshasa CD 300 F 4 NA 34 21352 0 21352CD001-058 253497 DRCongo Kinshasa CD 300 M 5 NA 34 162275 16 162291CD001-059 253810 DRCongo Kinshasa CD 300 F 3 NA 27 101736 48 101784CD001-061 253481 DRCongo Kinshasa CD 300 M 6 NA 33 128489 0 128489CD001-062 253476 DRCongo Kinshasa CD 300 F 3 NA 35 79128 0 79128CD001-063 253448 DRCongo Kinshasa CD 300 F 0.7260274 NA 22 223819 48 223867CD001-064 253691 DRCongo Kinshasa CD 300 F 3 NA 21 31651 0 31651CD001-065 253687 DRCongo Kinshasa CD 300 F 2 NA 35 285740 0 285740CD001-066 253685 DRCongo Kinshasa CD 300 M 3 NA 31 46723 0 46723CD001-068 253659 DRCongo Kinshasa CD 300 M 3 NA 33 49738 176 49914CD001-069 253647 DRCongo Kinshasa CD 300 M 7 NA 37 199830 0 199830CD001-070 253641 DRCongo Kinshasa CD 300 F 3 NA 32 36173 0 36173

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Hb (g/dL) Hct (%)


gam. count


CD001-071 253618 DRCongo Kinshasa CD 300 F 4 NA 25 72220 96 72316CD001-072 253621 DRCongo Kinshasa CD 300 M 5 NA 32 68326 0 68326CD001-073 253837 DRCongo Kinshasa CD 300 F 4 NA 28 101987 0 101987CD001-074 253840 DRCongo Kinshasa CD 300 M 7 NA 37 NA NA NACD001-075 253865 DRCongo Kinshasa CD 300 F 8 NA 35 30772 0 30772CD001-076 253864 DRCongo Kinshasa CD 300 M 8 NA 33 12434 0 12434CD001-077 253863 DRCongo Kinshasa CD 300 F 6 NA 30 184632 0 184632CD001-078 253884 DRCongo Kinshasa CD 300 M 6 NA 30 45216 16 45232CD001-079 253517 DRCongo Kinshasa CD 300 M 4 NA 25 50240 16 50256CD001-080 253518 DRCongo Kinshasa CD 300 M 0.9671233 NA 31 62298 0 62298CD001-081 253910 DRCongo Kinshasa CD 300 F 5 NA 28 21101 0 21101CD001-082 253539 DRCongo Kinshasa CD 300 M 6 NA 31 171318 0 171318CD001-083 253543 DRCongo Kinshasa CD 300 M 3 NA 26 88171 192 88363CD001-084 253546 DRCongo Kinshasa CD 300 F 7 NA 28 14067 128 14195CD001-085 253569 DRCongo Kinshasa CD 300 F 5 NA 25 43960 0 43960CD001-086 253572 DRCongo Kinshasa CD 300 M 5 NA 30 312744 0 312744CD001-087 253609 DRCongo Kinshasa CD 300 M 4 NA 24 36173 16 36189CD001-088 253612 DRCongo Kinshasa CD 300 M 3 NA 35 13188 0 13188CD001-089 254935 DRCongo Kinshasa CD 300 M 3 NA 35 360472 0 360472CD001-090 254931 DRCongo Kinshasa CD 300 M 6 NA 35 136276 16 136292CD001-091 254927 DRCongo Kinshasa CD 300 F 3 NA 32 160768 0 160768CD001-092 254968 DRCongo Kinshasa CD 300 M 2 NA 28 14067 80 14147CD001-093 254971 DRCongo Kinshasa CD 300 M 4 NA 27 74606 128 74734CD001-094 254989 DRCongo Kinshasa CD 300 F 6 NA 38 81138 0 81138CD001-095 254991 DRCongo Kinshasa CD 300 M 5 NA 40 50240 16 50256CD001-096 255010 DRCongo Kinshasa CD 300 F 8 NA 30 60288 0 60288CD001-097 255006 DRCongo Kinshasa CD 300 M 4 NA 29 43709 0 43709CD001-098 255046 DRCongo Kinshasa CD 300 M 5 NA 34 38434 96 38530CD001-099 255040 DRCongo Kinshasa CD 300 F 4 NA 35 70336 0 70336CD001-100 255037 DRCongo Kinshasa CD 300 M 2 NA 32 309478 0 309478CD001-101 255064 DRCongo Kinshasa CD 300 F 4 NA 30 214776 0 214776CD001-102 255076 DRCongo Kinshasa CD 300 M 5 NA 37 79002 0 79002CD001-103 255097 DRCongo Kinshasa CD 300 M 8 NA 27 23738 0 23738CD001-104 255101 DRCongo Kinshasa CD 300 M 4 NA 30 116808 0 116808CD001-105 255100 DRCongo Kinshasa CD 300 F 6 NA 30 45216 16 45232CD001-106 254520 DRCongo Kinshasa CD 300 M 7 NA 27 37303 0 37303CD001-107 254538 DRCongo Kinshasa CD 300 F 6 NA 31 124595 0 124595CD001-108 254542 DRCongo Kinshasa CD 300 M 7 NA 35 109900 0 109900CD001-109 254557 DRCongo Kinshasa CD 300 F 7 NA 35 52752 0 52752CD001-110 254584 DRCongo Kinshasa CD 300 F 6 NA 23 49110 32 49142

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Hb (g/dL) Hct (%)


gam. count


CD001-111 254585 DRCongo Kinshasa CD 300 M 6 NA 36 36173 0 36173CD001-112 254588 DRCongo Kinshasa CD 300 M 3 NA 32 72346 0 72346CD001-113 254612 DRCongo Kinshasa CD 300 F 7 NA 40 60288 0 60288CD001-114 254613 DRCongo Kinshasa CD 300 M 7 NA 35 39564 0 39564CD001-115 254614 DRCongo Kinshasa CD 300 F 7 NA 25 65940 16 65956CD001-116 254494 DRCongo Kinshasa CD 300 M 5 NA 39 102866 0 102866CD001-117 254487 DRCongo Kinshasa CD 300 F 2 NA 27 44086 0 44086CD001-118 254483 DRCongo Kinshasa CD 300 F 2 NA 30 229848 0 229848CD001-119 254451 DRCongo Kinshasa CD 300 M 5 NA 35 263760 0 263760CD001-120 254449 DRCongo Kinshasa CD 300 M 7 NA 34 59786 0 59786KH001-001 188118 Cambodia Pursat KH1 500 M 24 NA 45 45216 0 45216KH001-004 188209 Cambodia Pursat KH1 500 M 18 NA 34 46974 0 46974KH001-005 188208 Cambodia Pursat KH1 500 M 22 NA 39 127358 0 127358KH001-006 188127 Cambodia Pursat KH1 500 M 11 NA 32 108518 0 108518KH001-007 188129 Cambodia Pursat KH1 500 M 37 NA 42 100229 0 100229KH001-011 188204 Cambodia Pursat KH1 500 M 23 NA 39 9797 0 9797KH001-012 188198 Cambodia Pursat KH1 500 M 23 NA 39 240022 0 240022KH001-013 188144 Cambodia Pursat KH1 500 M 43 NA 25 34540 0 34540KH001-015 188181 Cambodia Pursat KH1 500 M 23 NA 43 43206 0 43206KH001-016 188176 Cambodia Pursat KH1 500 M 21 NA 45 107388 0 107388KH001-017 188174 Cambodia Pursat KH1 500 M 60 NA 40 55264 0 55264KH001-018 188173 Cambodia Pursat KH1 500 M 23 NA 32 32154 12058 44211KH001-020 194265 Cambodia Pursat KH1 500 M 30 NA 43 37806 0 37806KH001-021 194272 Cambodia Pursat KH1 500 M 33 NA 38 109774 0 109774KH001-022 194286 Cambodia Pursat KH1 500 M 33 NA 38 109774 0 109774KH001-023 194291 Cambodia Pursat KH1 500 M 15 NA 41 175086 0 175086KH001-024 194298 Cambodia Pursat KH1 500 M 18 NA 45 33912 0 33912KH001-025 194306 Cambodia Pursat KH1 500 M 25 NA 47 59032 0 59032KH001-026 194314 Cambodia Pursat KH1 500 M 31 NA 34 115301 0 115301KH001-028 194335 Cambodia Pursat KH1 500 M 39 NA 34 68326 16 68342KH001-029 194349 Cambodia Pursat KH1 500 M 29 NA 50 138160 0 138160KH001-030 199332 Cambodia Pursat KH1 500 M 26 NA 45 220428 0 220428KH001-031 199342 Cambodia Pursat KH1 500 F 26 NA 30 56520 0 56520KH001-032 199343 Cambodia Pursat KH1 500 M 18 NA 45 79128 0 79128KH001-034 193757 Cambodia Pursat KH1 500 M 28 NA 34 55515 4270 59786KH001-036 193959 Cambodia Pursat KH1 500 M 24 NA 37 55766 16 55782KH001-038 193778 Cambodia Pursat KH1 300 M 7 NA 26 107765 16 107781KH001-039 193972 Cambodia Pursat KH1 500 M 10 NA 40 125600 0 125600KH001-040 193974 Cambodia Pursat KH1 500 M 32 NA 31 81766 16 81782KH001-041 193987 Cambodia Pursat KH1 500 M 35 NA 48 42202 0 42202

Page 5 of 135


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Hb (g/dL) Hct (%)


gam. count


KH001-043 199352 Cambodia Pursat KH1 500 M 35 NA 40 75360 0 75360KH001-044 194008 Cambodia Pursat KH1 500 M 38 NA 31 19468 0 19468KH001-046 199364 Cambodia Pursat KH1 500 M 32 NA 55 193424 0 193424KH001-047 199363 Cambodia Pursat KH1 500 M 16 NA 44 138160 0 138160KH001-048 194024 Cambodia Pursat KH1 500 M 36 NA 41 77244 16 77260KH001-049 194037 Cambodia Pursat KH1 500 M 11 NA 36 22608 0 22608KH001-051 199356 Cambodia Pursat KH1 500 M 32 NA 39 132257 0 132257KH001-052 193787 Cambodia Pursat KH1 500 M 33 NA 46 69331 0 69331KH001-054 193799 Cambodia Pursat KH1 500 M 30 NA 39 39187 4898 44086KH001-055 194051 Cambodia Pursat KH1 500 M 22 NA 43 108016 0 108016KH001-056 193812 Cambodia Pursat KH1 500 M 37 NA 41 56646 5150 61795KH001-057 193821 Cambodia Pursat KH1 500 M 48 NA 33 41448 0 41448KH001-058 193822 Cambodia Pursat KH1 300 M 8 NA 28 28134 496 28630KH001-059 193849 Cambodia Pursat KH1 300 M 34 NA 44 71843 0 71843KH001-060 188056 Cambodia Pursat KH1 300 M 43 NA 39 53882 0 53882KH001-061 193838 Cambodia Pursat KH1 300 M 48 NA 41 41197 0 41197KH001-062 188068 Cambodia Pursat KH1 300 M 32 NA 49 67698 0 67698KH001-063 193825 Cambodia Pursat KH1 300 M 25 NA 40 90432 16 90448KH001-064 188073 Cambodia Pursat KH1 500 M 42 NA 43 81012 0 81012KH001-065 188075 Cambodia Pursat KH1 500 M 23 NA 48 12058 0 12058KH001-066 188082 Cambodia Pursat KH1 500 F 41 NA 47 165290 0 165290KH001-067 188087 Cambodia Pursat KH1 300 F 3 NA 40 15072 0 15072KH001-068 188096 Cambodia Pursat KH1 500 F 19 NA 40 50240 0 50240KH001-069 188098 Cambodia Pursat KH1 500 M 17 NA 50 182120 0 182120KH001-070 188101 Cambodia Pursat KH1 300 F 7 NA 37 74355 0 74355KH001-071 188102 Cambodia Pursat KH1 300 M 9 NA 35 26376 0 26376KH001-072 188104 Cambodia Pursat KH1 500 M 25 NA 32 12058 16 12074KH001-073 208405 Cambodia Pursat KH1 500 M 23 NA 32 48230 0 48230KH001-074 208412 Cambodia Pursat KH1 500 M 15 NA 33 29014 0 29014KH001-075 208422 Cambodia Pursat KH1 500 F 55 NA 39 39187 0 39187KH001-076 208424 Cambodia Pursat KH1 300 F 11 NA 35 87920 0 87920KH001-077 208433 Cambodia Pursat KH1 500 M 17 NA 40 45216 0 45216KH001-078 208435 Cambodia Pursat KH1 500 M 29 NA 37 60414 0 60414KH001-079 202262 Cambodia Pursat KH1 500 M 19 NA 38 57274 0 57274KH001-080 202274 Cambodia Pursat KH1 500 M 21 NA 40 130624 0 130624KH001-081 202283 Cambodia Pursat KH1 500 M 27 NA 35 74732 0 74732KH001-082 202288 Cambodia Pursat KH1 500 M 22 NA 45 113040 0 113040KH001-083 202293 Cambodia Pursat KH1 500 M 34 NA 40 95456 0 95456KH001-084 202303 Cambodia Pursat KH1 500 F 50 NA 40 150720 0 150720KH001-086 202310 Cambodia Pursat KH1 500 M 18 NA 42 284861 0 284861

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Hb (g/dL) Hct (%)


gam. count


KH001-087 202323 Cambodia Pursat KH1 500 M 24 NA 36 36173 0 36173KH001-088 202330 Cambodia Pursat KH1 500 F 17 NA 38 162275 0 162275KH001-089 202328 Cambodia Pursat KH1 500 M 18 NA 36 67824 0 67824KH001-090 202340 Cambodia Pursat KH1 500 M 34 NA 36 18086 32 18118KH001-091 202353 Cambodia Pursat KH1 500 M 43 NA 43 32405 0 32405KH001-092 194459 Cambodia Pursat KH1 500 M 26 NA 39 215530 0 215530KH001-093 194468 Cambodia Pursat KH1 500 M 23 NA 46 92442 64 92506KH001-094 194474 Cambodia Pursat KH1 500 M 54 NA 35 21980 0 21980KH001-095 194491 Cambodia Pursat KH1 500 M 58 NA 40 15072 0 15072KH001-096 194503 Cambodia Pursat KH1 500 M 50 NA 36 22608 0 22608KH001-097 194553 Cambodia Pursat KH1 500 M 26 NA 38 23864 16 23880KH001-098 194550 Cambodia Pursat KH1 500 F 15 NA 36 58781 0 58781KH001-099 194524 Cambodia Pursat KH1 500 M 20 NA 38 57274 144 57418KH001-100 202110 Cambodia Pursat KH1 500 M 39 NA 32 48230 0 48230KH001-101 202097 Cambodia Pursat KH1 500 M 35 NA 37 79002 0 79002KH001-102 202073 Cambodia Pursat KH1 500 M 31 NA 37 246302 0 246302KH001-103 202074 Cambodia Pursat KH1 500 M 24 NA 40 35168 160 35328KH001-104 216376 Cambodia Pursat KH1 500 M 45 NA 39 24492 0 24492KH001-105 216377 Cambodia Pursat KH1 500 M 33 NA 38 38182 128 38310KH001-106 216385 Cambodia Pursat KH1 500 M 25 NA 44 165792 0 165792KH001-107 216391 Cambodia Pursat KH1 300 F 9 NA 34 72597 0 72597KH001-108 216395 Cambodia Pursat KH1 500 M 50 NA 43 43206 0 43206KH001-109 216402 Cambodia Pursat KH1 500 M 21 NA 32 40192 32 40224KH001-110 216407 Cambodia Pursat KH1 500 M 20 NA 38 19091 0 19091KH001-111 217165 Cambodia Pursat KH1 500 M 18 NA 34 25622 96 25718KH001-112 217466 Cambodia Pursat KH1 500 M 29 NA 30 45216 96 45312KH001-113 217468 Cambodia Pursat KH1 500 M 29 NA 38 33410 0 33410KH001-114 215759 Cambodia Pursat KH1 500 M 21 NA 40 30144 0 30144KH001-116 236285 Cambodia Pursat KH1 500 M 13 NA 29 10927 0 10927KH001-117 236300 Cambodia Pursat KH1 500 M 29 NA 34 25622 0 25622KH001-118 236292 Cambodia Pursat KH1 500 M 25 NA 35 35168 0 35168KH001-119 236308 Cambodia Pursat KH1 300 M 9 NA 28 49235 0 49235KH001-120 236363 Cambodia Pursat KH1 500 M 27 NA 39 48984 9797 58781KH002-001 188418 Cambodia Preah Vihear KH2 500 M 29 NA 40 65312 0 65312KH002-002 188426 Cambodia Preah Vihear KH2 500 F 15 NA 40 45216 0 45216KH002-003 188428 Cambodia Preah Vihear KH2 500 F 44 NA 38 57274 0 57274KH002-005 188439 Cambodia Preah Vihear KH2 500 M 15 NA 38 33410 0 33410KH002-006 188440 Cambodia Preah Vihear KH2 500 F 11 NA 37 13942 0 13942KH002-007 188442 Cambodia Preah Vihear KH2 300 M 7 NA 31 54510 0 54510KH002-008 188452 Cambodia Preah Vihear KH2 500 M 38 NA 42 47477 0 47477

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Hb (g/dL) Hct (%)


gam. count


KH002-009 188455 Cambodia Preah Vihear KH2 500 M 15 NA 35 74732 0 74732KH002-010 188458 Cambodia Preah Vihear KH2 500 M 16 NA 34 170816 0 170816KH002-011 188464 Cambodia Preah Vihear KH2 500 M 21 NA 43 178226 0 178226KH002-012 188468 Cambodia Preah Vihear KH2 500 M 23 NA 46 80886 0 80886KH002-013 188470 Cambodia Preah Vihear KH2 500 M 16 NA 35 171444 0 171444KH002-014 188359 Cambodia Preah Vihear KH2 500 M 54 NA 42 52752 0 52752KH002-015 188364 Cambodia Preah Vihear KH2 500 F 36 NA 41 41197 0 41197KH002-016 188365 Cambodia Preah Vihear KH2 500 M 18 NA 48 102490 0 102490KH002-017 188367 Cambodia Preah Vihear KH2 500 M 16 NA 42 311237 0 311237KH002-018 188406 Cambodia Preah Vihear KH2 500 F 12 NA 33 62172 0 62172KH002-019 188409 Cambodia Preah Vihear KH2 500 F 14 NA 32 80384 0 80384KH002-020 188408 Cambodia Preah Vihear KH2 300 F 9 NA 28 52752 0 52752KH002-021 188492 Cambodia Preah Vihear KH2 500 M 29 NA 36 72346 0 72346KH002-022 188489 Cambodia Preah Vihear KH2 500 M 11 NA 26 52250 0 52250KH002-023 198471 Cambodia Preah Vihear KH2 500 M 20 NA 41 56646 0 56646KH002-024 198476 Cambodia Preah Vihear KH2 500 F 11 NA 38 42955 0 42955KH002-025 198484 Cambodia Preah Vihear KH2 500 M 25 NA 34 93949 0 93949KH002-027 198486 Cambodia Preah Vihear KH2 500 F 21 NA 40 55264 0 55264KH002-028 198487 Cambodia Preah Vihear KH2 500 F 6 NA 27 67824 0 67824KH002-029 198499 Cambodia Preah Vihear KH2 300 F 4 NA 33 53882 0 53882KH002-030 198496 Cambodia Preah Vihear KH2 500 F 19 NA 28 38685 0 38685KH002-031 198514 Cambodia Preah Vihear KH2 500 M 22 NA 33 62172 0 62172KH002-032 198516 Cambodia Preah Vihear KH2 500 F 51 NA 34 42704 0 42704KH002-033 198525 Cambodia Preah Vihear KH2 500 M 22 NA 38 57274 0 57274KH002-034 198527 Cambodia Preah Vihear KH2 500 M 40 NA 39 102866 0 102866KH002-035 198536 Cambodia Preah Vihear KH2 500 F 26 NA 26 32656 64 32720KH002-036 198538 Cambodia Preah Vihear KH2 500 F 12 NA 32 164787 0 164787KH002-037 198540 Cambodia Preah Vihear KH2 300 F 9 NA 34 51245 0 51245KH002-038 198542 Cambodia Preah Vihear KH2 300 M 9 NA 26 71843 32 71875KH002-039 198551 Cambodia Preah Vihear KH2 500 M 21 NA 43 37806 0 37806KH002-040 198560 Cambodia Preah Vihear KH2 500 M 19 NA 34 34163 304 34467KH002-041 198562 Cambodia Preah Vihear KH2 500 M 13 NA 34 119571 0 119571KH002-042 198584 Cambodia Preah Vihear KH2 500 M 29 NA 28 56269 0 56269KH002-043 198564 Cambodia Preah Vihear KH2 500 F 22 NA 40 45216 0 45216KH002-044 207295 Cambodia Preah Vihear KH2 500 F 24 NA 40 45216 0 45216KH002-045 198574 Cambodia Preah Vihear KH2 500 F 48 NA 39 44086 0 44086KH002-046 207297 Cambodia Preah Vihear KH2 500 F 17 NA 31 38936 0 38936KH002-047 207446 Cambodia Preah Vihear KH2 500 F 13 NA 35 21980 0 21980KH002-048 198573 Cambodia Preah Vihear KH2 500 F 17 NA 44 82896 0 82896KH002-049 207448 Cambodia Preah Vihear KH2 300 M 15 NA 32 104499 0 104499

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Hb (g/dL) Hct (%)


gam. count


KH002-050 207450 Cambodia Preah Vihear KH2 500 M 12 NA 38 85910 0 85910KH002-051 207459 Cambodia Preah Vihear KH2 500 M 29 NA 42 174082 0 174082KH002-052 207468 Cambodia Preah Vihear KH2 500 M 31 NA 37 79002 0 79002KH002-053 207470 Cambodia Preah Vihear KH2 500 M 17 NA 38 62046 0 62046KH002-054 207480 Cambodia Preah Vihear KH2 500 M 45 NA 40 105504 0 105504KH002-055 207496 Cambodia Preah Vihear KH2 500 M 47 NA 38 52501 0 52501KH002-056 207488 Cambodia Preah Vihear KH2 500 M 16 NA 34 68326 0 68326KH002-057 207302 Cambodia Preah Vihear KH2 500 M 20 NA 41 92693 0 92693KH002-058 207311 Cambodia Preah Vihear KH2 500 M 22 NA 45 22608 0 22608KH002-059 207313 Cambodia Preah Vihear KH2 500 M 17 NA 50 81640 0 81640KH002-060 207322 Cambodia Preah Vihear KH2 500 F 27 NA 43 43206 0 43206KH002-061 207324 Cambodia Preah Vihear KH2 500 M 10 NA 38 85910 0 85910KH002-062 207334 Cambodia Preah Vihear KH2 500 M 46 NA 50 56520 0 56520KH002-063 207336 Cambodia Preah Vihear KH2 500 M 17 NA 35 35168 0 35168KH002-064 198185 Cambodia Preah Vihear KH2 500 F 14 NA 31 85659 0 85659KH002-065 198187 Cambodia Preah Vihear KH2 500 M 13 NA 35 17584 0 17584KH002-066 198196 Cambodia Preah Vihear KH2 500 M 20 NA 41 51496 0 51496KH002-067 198205 Cambodia Preah Vihear KH2 500 F 20 NA 43 81012 0 81012KH002-068 198207 Cambodia Preah Vihear KH2 500 F 17 NA 37 41825 0 41825KH002-069 198216 Cambodia Preah Vihear KH2 500 M 19 NA 39 39187 0 39187KH002-070 198225 Cambodia Preah Vihear KH2 500 F 43 NA 39 39187 0 39187KH002-071 198234 Cambodia Preah Vihear KH2 500 M 26 NA 52 71843 0 71843KH002-072 198243 Cambodia Preah Vihear KH2 500 M 21 NA 34 17082 0 17082KH002-073 198252 Cambodia Preah Vihear KH2 500 M 20 NA 41 61795 0 61795KH002-074 198261 Cambodia Preah Vihear KH2 500 M 58 NA 41 25748 0 25748KH002-075 198270 Cambodia Preah Vihear KH2 500 M 24 NA 46 92442 0 92442KH002-076 198273 Cambodia Preah Vihear KH2 500 M 28 NA 47 70838 0 70838KH002-077 198275 Cambodia Preah Vihear KH2 500 F 16 NA 42 52752 0 52752KH002-078 207339 Cambodia Preah Vihear KH2 500 M 27 NA 44 88422 0 88422KH002-079 207341 Cambodia Preah Vihear KH2 500 M 8 NA 29 123842 0 123842KH002-081 207358 Cambodia Preah Vihear KH2 500 M 42 NA 34 162275 176 162451KH002-082 198157 Cambodia Preah Vihear KH2 300 F 6 NA 30 48984 0 48984KH002-083 198159 Cambodia Preah Vihear KH2 300 F 4 NA 29 134769 0 134769KH002-084 198161 Cambodia Preah Vihear KH2 500 F 12 NA 34 38434 0 38434KH002-085 198163 Cambodia Preah Vihear KH2 300 F 5 NA 33 53882 0 53882KH002-086 198165 Cambodia Preah Vihear KH2 500 M 5 NA 33 16579 0 16579KH002-087 198173 Cambodia Preah Vihear KH2 500 M 19 NA 39 63679 0 63679KH002-088 198182 Cambodia Preah Vihear KH2 500 M 52 NA 38 238640 32 238672KH002-089 213743 Cambodia Preah Vihear KH2 300 F 8 NA 31 46723 0 46723KH002-090 213751 Cambodia Preah Vihear KH2 500 M 32 NA 38 23864 0 23864

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Hb (g/dL) Hct (%)


gam. count


KH002-091 213753 Cambodia Preah Vihear KH2 500 M 10 NA 32 48230 0 48230KH002-092 213764 Cambodia Preah Vihear KH2 500 M 36 NA 41 46346 0 46346KH002-093 236214 Cambodia Preah Vihear KH2 500 F 14 NA 29 69206 0 69206KH002-094 213785 Cambodia Preah Vihear KH2 500 M 20 NA 34 51245 0 51245KH002-095 213793 Cambodia Preah Vihear KH2 500 M 10 NA 26 32656 0 32656KH002-096 213808 Cambodia Preah Vihear KH2 500 M 29 NA 28 31651 0 31651KH002-097 213810 Cambodia Preah Vihear KH2 500 M 18 NA 34 42704 0 42704KH002-098 236247 Cambodia Preah Vihear KH2 500 M 42 NA 36 135648 0 135648KH002-099 236258 Cambodia Preah Vihear KH2 500 M 39 NA 42 79128 0 79128KH002-100 236260 Cambodia Preah Vihear KH2 300 M 6 NA 36 131126 0 131126KH002-101 236262 Cambodia Preah Vihear KH2 500 M 14 NA 26 120827 0 120827KH002-102 236274 Cambodia Preah Vihear KH2 500 M 17 NA 49 116934 0 116934KH002-103 236084 Cambodia Preah Vihear KH2 500 M 37 NA 45 22608 0 22608KH002-104 236092 Cambodia Preah Vihear KH2 500 M 37 NA 39 244920 0 244920KH002-105 236131 Cambodia Preah Vihear KH2 500 F 12 NA 33 87041 0 87041KH002-106 236170 Cambodia Preah Vihear KH2 500 F 44 NA 38 14318 0 14318KH002-107 236172 Cambodia Preah Vihear KH2 500 M 23 NA 39 34289 0 34289KH002-108 236175 Cambodia Preah Vihear KH2 500 M 11 NA 34 196438 0 196438KH002-109 236376 Cambodia Preah Vihear KH2 500 M 19 NA 42 36926 0 36926KH002-110 236379 Cambodia Preah Vihear KH2 500 M 26 NA 39 176342 0 176342KH002-111 236447 Cambodia Preah Vihear KH2 500 F 29 NA 34 55515 0 55515KH002-112 236438 Cambodia Preah Vihear KH2 500 M 27 NA 45 84780 0 84780KH002-114 236427 Cambodia Preah Vihear KH2 500 M 18 NA 42 52752 0 52752KH002-115 236424 Cambodia Preah Vihear KH2 500 M 6 NA 32 180864 0 180864KH002-116 236416 Cambodia Preah Vihear KH2 500 M 19 NA 40 75360 0 75360KH002-117 216493 Cambodia Preah Vihear KH2 500 M 16 NA 43 86413 0 86413KH002-118 216558 Cambodia Preah Vihear KH2 500 M 24 NA 48 48230 0 48230KH002-119 216571 Cambodia Preah Vihear KH2 500 M 39 NA 33 33158 0 33158KH002-120 216557 Cambodia Preah Vihear KH2 500 M 27 NA 41 15449 0 15449KH003-004 188680 Cambodia Ratanakiri KH3 300 F 55 NA 39 73476 0 73476KH003-009 188531 Cambodia Ratanakiri KH3 500 M 15 NA 37 88297 0 88297KH003-010 188537 Cambodia Ratanakiri KH3 500 M 8 NA 31 112914 0 112914KH003-011 188708 Cambodia Ratanakiri KH3 300 M 6 NA 30 33912 0 33912KH003-012 198592 Cambodia Ratanakiri KH3 500 M 29 NA 44 38685 0 38685KH003-013 198988 Cambodia Ratanakiri KH3 500 F 14 NA 33 29014 0 29014KH003-015 198991 Cambodia Ratanakiri KH3 500 F 11 NA 26 71843 0 71843KH003-016 198993 Cambodia Ratanakiri KH3 500 M 13 NA 33 16579 0 16579KH003-017 198995 Cambodia Ratanakiri KH3 500 M 15 NA 46 28888 0 28888KH003-018 199002 Cambodia Ratanakiri KH3 500 M 22 NA 38 38182 0 38182KH003-019 199011 Cambodia Ratanakiri KH3 500 M 40 NA 35 149464 0 149464

Page 10 of 135


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Hb (g/dL) Hct (%)


gam. count


KH003-020 199012 Cambodia Ratanakiri KH3 500 F 13 NA 39 117562 0 117562KH003-021 199016 Cambodia Ratanakiri KH3 500 M 15 NA 38 128866 0 128866KH003-022 198647 Cambodia Ratanakiri KH3 500 M 23 NA 47 35419 0 35419KH003-024 198650 Cambodia Ratanakiri KH3 300 M 6 NA 25 53380 0 53380KH003-025 198651 Cambodia Ratanakiri KH3 500 M 16 NA 44 193424 0 193424KH003-027 199029 Cambodia Ratanakiri KH3 500 F 13 NA 38 81138 0 81138KH003-028 199071 Cambodia Ratanakiri KH3 500 M 19 NA 50 50240 0 50240KH003-029 202663 Cambodia Ratanakiri KH3 500 F 14 NA 39 93070 0 93070KH003-030 202662 Cambodia Ratanakiri KH3 300 M 2 NA 37 51119 0 51119KH003-031 202667 Cambodia Ratanakiri KH3 500 F 23 NA 41 87543 0 87543KH003-032 202477 Cambodia Ratanakiri KH3 300 M 7 NA 40 195936 0 195936KH003-033 202675 Cambodia Ratanakiri KH3 500 F 14 NA 40 5024 0 5024KH003-034 188599 Cambodia Ratanakiri KH3 500 M 48 NA 45 310860 0 310860KH003-035 202494 Cambodia Ratanakiri KH3 300 F 9 NA 38 71592 0 71592KH003-036 202681 Cambodia Ratanakiri KH3 300 M 7 NA 30 199704 0 199704KH003-037 202682 Cambodia Ratanakiri KH3 500 M 28 NA 42 152981 0 152981KH003-038 202516 Cambodia Ratanakiri KH3 500 M 14 NA 44 38685 0 38685KH003-039 202687 Cambodia Ratanakiri KH3 300 M 9 NA 40 45216 0 45216KH003-040 202686 Cambodia Ratanakiri KH3 500 M 13 NA 43 183627 0 183627KH003-041 202693 Cambodia Ratanakiri KH3 500 M 38 NA 42 94954 0 94954KH003-042 202692 Cambodia Ratanakiri KH3 300 M 4 NA 38 167048 0 167048KH003-043 202540 Cambodia Ratanakiri KH3 500 F 16 NA 42 58027 0 58027KH003-044 202700 Cambodia Ratanakiri KH3 500 F 13 NA 37 13942 0 13942KH003-045 207965 Cambodia Ratanakiri KH3 500 F 19 NA 37 18589 0 18589KH003-046 207970 Cambodia Ratanakiri KH3 500 F 13 NA 37 74355 0 74355KH003-047 207987 Cambodia Ratanakiri KH3 500 M 19 NA 47 94451 0 94451KH003-048 207998 Cambodia Ratanakiri KH3 500 M 11 NA 42 100229 0 100229KH003-049 207999 Cambodia Ratanakiri KH3 500 M 17 NA 50 87920 0 87920KH003-050 208017 Cambodia Ratanakiri KH3 500 F 35 NA 47 29516 0 29516KH003-051 208021 Cambodia Ratanakiri KH3 500 M 16 NA 39 97968 0 97968KH003-052 208018 Cambodia Ratanakiri KH3 500 M 13 NA 43 189028 0 189028KH003-053 208022 Cambodia Ratanakiri KH3 500 M 10 NA 40 115552 0 115552KH003-054 207556 Cambodia Ratanakiri KH3 500 M 12 NA 35 65940 0 65940KH003-055 207557 Cambodia Ratanakiri KH3 500 F 6 NA 27 30521 64 30585KH003-056 207558 Cambodia Ratanakiri KH3 500 M 18 NA 36 76867 96 76963KH003-057 207593 Cambodia Ratanakiri KH3 300 F 8 NA 33 74606 0 74606KH003-058 207592 Cambodia Ratanakiri KH3 500 M 15 NA 38 66819 0 66819KH003-059 207586 Cambodia Ratanakiri KH3 500 M 42 NA 38 62046 0 62046KH003-060 207587 Cambodia Ratanakiri KH3 500 M 23 NA 40 60288 0 60288KH003-061 207610 Cambodia Ratanakiri KH3 500 M 37 NA 46 57776 0 57776

Page 11 of 135


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color



Hb (g/dL) Hct (%)


gam. count


KH003-063 207751 Cambodia Ratanakiri KH3 300 M 5 NA 33 74606 0 74606KH003-064 207776 Cambodia Ratanakiri KH3 500 F 18 NA 40 105504 0 105504KH003-065 207799 Cambodia Ratanakiri KH3 500 M 14 NA 38 186139 0 186139KH003-066 207800 Cambodia Ratanakiri KH3 500 F 15 NA 28 21101 0 21101KH003-067 207655 Cambodia Ratanakiri KH3 500 M 47 NA 31 73978 0 73978KH003-068 207710 Cambodia Ratanakiri KH3 500 M 15 NA 38 47728 0 47728KH003-069 207715 Cambodia Ratanakiri KH3 500 M 13 NA 41 46346 0 46346KH003-070 207722 Cambodia Ratanakiri KH3 500 M 11 NA 35 26376 0 26376KH003-071 207727 Cambodia Ratanakiri KH3 300 F 9 NA 28 24618 0 24618KH003-072 207842 Cambodia Ratanakiri KH3 500 M 15 NA 36 40694 0 40694KH003-073 207861 Cambodia Ratanakiri KH3 500 F 25 NA 40 50240 0 50240KH003-074 207862 Cambodia Ratanakiri KH3 500 F 31 NA 30 71592 0 71592KH003-075 207875 Cambodia Ratanakiri KH3 500 M 16 NA 44 33158 0 33158KH003-076 207891 Cambodia Ratanakiri KH3 500 M 11 NA 35 101108 0 101108KH003-077 207909 Cambodia Ratanakiri KH3 500 M 13 NA 38 76365 0 76365KH003-078 207919 Cambodia Ratanakiri KH3 300 M 7 NA 33 62172 0 62172KH003-079 252132 Cambodia Ratanakiri KH3 300 M 7 NA 26 104499 0 104499KH003-080 207927 Cambodia Ratanakiri KH3 300 F 3 NA 31 31149 0 31149KH003-081 207929 Cambodia Ratanakiri KH3 500 M 11 NA 36 76867 0 76867KH003-082 207930 Cambodia Ratanakiri KH3 500 M 14 NA 39 142054 0 142054KH003-083 213466 Cambodia Ratanakiri KH3 500 M 16 NA 36 22608 0 22608KH003-084 213469 Cambodia Ratanakiri KH3 500 M 5 NA 34 98219 0 98219KH003-085 213472 Cambodia Ratanakiri KH3 500 M 7 NA 35 83524 0 83524KH003-086 213494 Cambodia Ratanakiri KH3 500 F 16 NA 39 34289 0 34289KH003-087 213540 Cambodia Ratanakiri KH3 500 F 11 NA 37 32530 0 32530KH003-088 213373 Cambodia Ratanakiri KH3 500 M 14 NA 36 40694 0 40694KH003-089 213379 Cambodia Ratanakiri KH3 500 F 30 NA 39 19594 0 19594KH003-090 213504 Cambodia Ratanakiri KH3 300 M 7 NA 34 25622 144 25766KH003-091 213505 Cambodia Ratanakiri KH3 500 F 17 NA 42 47477 0 47477KH003-092 213510 Cambodia Ratanakiri KH3 500 M 40 NA 38 81138 16 81154KH003-094 213536 Cambodia Ratanakiri KH3 500 F 15 NA 30 71592 0 71592KH003-095 213537 Cambodia Ratanakiri KH3 300 F 8 NA 26 199202 0 199202KH003-096 213535 Cambodia Ratanakiri KH3 300 M 2 NA 32 24115 32 24147KH003-097 213548 Cambodia Ratanakiri KH3 500 M 53 NA 34 17082 0 17082KH003-098 213560 Cambodia Ratanakiri KH3 500 M 42 NA 38 23864 0 23864KH003-099 213549 Cambodia Ratanakiri KH3 500 F 44 NA 26 71843 32 71875KH003-100 214074 Cambodia Ratanakiri KH3 500 M 18 NA 37 74355 9294 83650KH003-101 213603 Cambodia Ratanakiri KH3 500 M 18 NA 44 93949 0 93949KH003-102 213601 Cambodia Ratanakiri KH3 500 M 15 NA 40 105504 0 105504KH003-103 213605 Cambodia Ratanakiri KH3 300 M 8 NA 39 171444 0 171444

Page 12 of 135


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color



Hb (g/dL) Hct (%)


gam. count


KH003-104 213613 Cambodia Ratanakiri KH3 500 F 10 NA 29 258610 0 258610KH003-105 214127 Cambodia Ratanakiri KH3 500 M 12 NA 39 53882 0 53882KH003-107 213626 Cambodia Ratanakiri KH3 500 F 13 NA 34 21352 0 21352KH003-109 215861 Cambodia Ratanakiri KH3 500 M 20 NA 45 62172 0 62172KH003-110 215881 Cambodia Ratanakiri KH3 500 M 20 NA 45 135648 0 135648KH003-111 215899 Cambodia Ratanakiri KH3 500 M 20 NA 47 23613 0 23613KH003-112 215909 Cambodia Ratanakiri KH3 500 M 14 NA 36 99475 0 99475KH003-113 215956 Cambodia Ratanakiri KH3 500 M 47 NA 48 54259 0 54259KH003-114 215706 Cambodia Ratanakiri KH3 500 F 15 NA 40 25120 0 25120KH003-115 215950 Cambodia Ratanakiri KH3 500 F 22 NA 39 53882 0 53882KH003-116 215933 Cambodia Ratanakiri KH3 500 F 38 NA 43 32405 0 32405KH003-117 215718 Cambodia Ratanakiri KH3 500 M 33 NA 40 30144 0 30144KH003-118 215940 Cambodia Ratanakiri KH3 500 F 18 NA 39 34289 0 34289KH003-119 215723 Cambodia Ratanakiri KH3 500 F 5 NA 25 31400 0 31400KH003-120 216172 Cambodia Ratanakiri KH3 300 F 7 NA 42 21101 0 21101KH004-001 182486 Cambodia Pailin KH4 500 F 13 12.8 41 108142 0 108142KH004-002 182505 Cambodia Pailin KH4 300 M 31 11.2 40 40192 0 40192KH004-005 182576 Cambodia Pailin KH4 300 M 21 16.2 50 25120 0 25120KH004-007 182409 Cambodia Pailin KH4 300 M 22 13.2 42 137155 0 137155KH004-008 183791 Cambodia Pailin KH4 300 M 57 12.7 38 66819 0 66819KH004-012 183632 Cambodia Pailin KH4 500 M 45 13.2 40 50240 0 50240KH004-013 195809 Cambodia Pailin KH4 500 M 19 9.2 30 41448 80 41528KH004-014 195808 Cambodia Pailin KH4 500 M 54 13.5 41 30898 0 30898KH004-015 183725 Cambodia Pailin KH4 500 M 37 14.7 45 101736 0 101736KH004-016 195807 Cambodia Pailin KH4 500 M 20 10 31 27255 16 27271KH004-018 183504 Cambodia Pailin KH4 500 M 23 9.2 26 91437 1200 92637KH004-019 183551 Cambodia Pailin KH4 500 M 38 14.9 47 64935 0 64935KH004-020 183564 Cambodia Pailin KH4 500 M 18 12.1 40 70336 0 70336KH004-021 195803 Cambodia Pailin KH4 500 M 22 12.5 38 23864 32 23896KH004-022 195804 Cambodia Pailin KH4 500 M 25 12.3 40 10048 176 10224KH004-023 195684 Cambodia Pailin KH4 500 M 33 11.5 37 153358 0 153358KH004-024 195802 Cambodia Pailin KH4 500 M 24 14.8 49 43081 0 43081KH004-025 195801 Cambodia Pailin KH4 500 M 29 15.2 47 41322 0 41322KH004-027 195641 Cambodia Pailin KH4 500 M 50 12.7 36 45216 0 45216KH004-028 195806 Cambodia Pailin KH4 500 M 21 15.4 46 69331 0 69331KH004-030 195872 Cambodia Pailin KH4 500 M 39 15.1 46 63554 0 63554KH004-031 195835 Cambodia Pailin KH4 500 M 47 10.7 33 157502 0 157502KH004-032 195864 Cambodia Pailin KH4 500 M 23 14 44 38685 0 38685KH004-033 195886 Cambodia Pailin KH4 500 F 46 13.1 42 31651 0 31651KH004-034 196276 Cambodia Pailin KH4 500 M 25 13.8 46 57776 0 57776

Page 13 of 135


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color



Hb (g/dL) Hct (%)


gam. count


KH004-035 196308 Cambodia Pailin KH4 500 M 24 10 32 40192 32 40224KH004-036 196328 Cambodia Pailin KH4 500 M 44 12.1 39 88171 16 88187KH004-037 196400 Cambodia Pailin KH4 500 M 18 12.6 41 221433 0 221433KH004-038 196438 Cambodia Pailin KH4 500 M 37 13.7 44 71843 0 71843KH004-039 196449 Cambodia Pailin KH4 500 M 44 13.7 43 27004 0 27004KH004-040 196014 Cambodia Pailin KH4 500 M 34 13.3 42 94954 0 94954KH004-041 196037 Cambodia Pailin KH4 500 M 28 12.4 40 25120 0 25120KH004-042 196050 Cambodia Pailin KH4 500 M 22 13.6 45 243036 0 243036KH004-043 209174 Cambodia Pailin KH4 500 M 51 13.9 45 45216 0 45216KH004-044 209188 Cambodia Pailin KH4 500 M 30 13.7 44 11053 0 11053KH004-045 209199 Cambodia Pailin KH4 500 M 18 12.2 46 138662 0 138662KH004-046 209357 Cambodia Pailin KH4 500 F 41 10.1 28 63302 32 63334KH004-047 209370 Cambodia Pailin KH4 500 M 47 10.5 32 60288 16 60304KH004-048 209372 Cambodia Pailin KH4 500 M 27 13 40 65312 0 65312KH004-049 209423 Cambodia Pailin KH4 500 F 18 12.3 36 63302 0 63302KH004-051 195514 Cambodia Pailin KH4 500 M 10 11.4 35 3712 16 3728KH004-052 195526 Cambodia Pailin KH4 500 M 51 12.8 40 15072 0 15072KH004-053 209622 Cambodia Pailin KH4 500 M 32 17.5 50 75360 0 75360KH004-054 208981 Cambodia Pailin KH4 500 M 35 16.9 42 15826 0 15826KH004-055 208996 Cambodia Pailin KH4 500 F 14 13.6 45 389988 0 389988KH004-056 209469 Cambodia Pailin KH4 500 M 23 10.9 31 93446 80 93526KH004-057 209497 Cambodia Pailin KH4 500 M 27 12.3 38 14318 0 14318KH004-058 209744 Cambodia Pailin KH4 500 M 35 12.4 40 80384 0 80384KH004-059 209769 Cambodia Pailin KH4 500 M 23 14.5 44 11053 0 11053KH004-060 209803 Cambodia Pailin KH4 500 M 54 14.2 43 194429 0 194429KH004-061 209874 Cambodia Pailin KH4 500 M 18 13.6 43 21603 0 21603KH004-062 209919 Cambodia Pailin KH4 500 M 22 14.3 39 24492 0 24492KH004-063 209936 Cambodia Pailin KH4 500 F 11 10.9 35 61544 0 61544KH004-064 209713 Cambodia Pailin KH4 500 M 34 14 41 97842 0 97842KH004-065 209716 Cambodia Pailin KH4 500 M 34 13.4 44 44211 0 44211KH004-066 209732 Cambodia Pailin KH4 500 M 22 15.2 49 24618 0 24618KH004-067 209246 Cambodia Pailin KH4 500 M 19 14.3 46 86664 880 87544KH004-068 222084 Cambodia Pailin KH4 500 M 19 12.7 39 97968 0 97968KH004-069 222103 Cambodia Pailin KH4 500 M 18 14.2 42 10550 0 10550KH004-070 222135 Cambodia Pailin KH4 500 M 42 13.8 41 25748 0 25748KH004-071 222257 Cambodia Pailin KH4 500 F 26 11.1 33 161647 16 161663KH004-073 209100 Cambodia Pailin KH4 500 F 41 11.1 32 20096 0 20096KH004-073 222060 Cambodia Pailin KH4 500 F 41 11.1 32 20096 0 20096KH004-074 209121 Cambodia Pailin KH4 500 F 55 12.4 37 46472 0 46472KH004-075 209127 Cambodia Pailin KH4 500 F 18 10.3 33 20724 0 20724

Page 14 of 135


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color



Hb (g/dL) Hct (%)


gam. count


KH004-076 222166 Cambodia Pailin KH4 500 M 13 9.5 31 35042 0 35042KH004-077 221977 Cambodia Pailin KH4 500 M 19 8.8 27 27130 1024 28154KH004-078 221813 Cambodia Pailin KH4 500 M 16 10.1 29 10927 640 11567KH004-079 221844 Cambodia Pailin KH4 500 M 22 13.4 42 42202 0 42202KH004-080 222001 Cambodia Pailin KH4 500 M 19 11.4 37 32530 0 32530KH004-081 235369 Cambodia Pailin KH4 500 M 39 13.5 40 35168 0 35168KH004-082 235340 Cambodia Pailin KH4 500 M 24 16 48 108518 0 108518KH004-083 235303 Cambodia Pailin KH4 500 M 31 14.1 43 102615 0 102615KH004-084 234600 Cambodia Pailin KH4 500 M 44 12.9 39 58781 32 58813KH004-084 235312 Cambodia Pailin KH4 500 M 44 12.9 39 58781 32 58813KH004-085 235385 Cambodia Pailin KH4 500 M 22 13.6 43 10802 0 10802KH004-086 235404 Cambodia Pailin KH4 500 M 17 12.1 36 13565 16 13581KH004-087 235415 Cambodia Pailin KH4 500 M 36 13.9 42 26376 0 26376KH004-088 235438 Cambodia Pailin KH4 500 M 11 13.3 41 87543 0 87543KH004-089 234609 Cambodia Pailin KH4 500 M 18 14.3 44 82896 0 82896KH004-090 234627 Cambodia Pailin KH4 500 M 43 12.1 35 13188 0 13188KH004-091 231253 Cambodia Pailin KH4 500 M 56 11.4 34 102490 0 102490KH004-092 231270 Cambodia Pailin KH4 500 F 50 13.2 41 15449 0 15449KH004-093 231281 Cambodia Pailin KH4 500 F 37 11.8 34 25622 16 25638KH004-094 234486 Cambodia Pailin KH4 500 M 23 13.9 43 43206 0 43206KH004-095 234502 Cambodia Pailin KH4 500 M 15 10.3 32 40192 32 40224KH004-096 234541 Cambodia Pailin KH4 500 M 27 15.8 47 70838 0 70838KH004-097 234684 Cambodia Pailin KH4 500 M 28 13.1 42 116054 0 116054KH004-098 234692 Cambodia Pailin KH4 500 M 43 15.7 44 60790 0 60790KH004-099 234731 Cambodia Pailin KH4 500 M 52 11.3 34 34163 0 34163KH004-100 231370 Cambodia Pailin KH4 500 M 25 13.7 45 113040 0 113040LA001-001 189212 Laos Attapeu LA 500 F 15 NA 38 52501 0 52501LA001-002 189217 Laos Attapeu LA 300 F 8 NA 34 12811 0 12811LA001-003 189222 Laos Attapeu LA 500 F 43 NA 32 20096 0 20096LA001-004 189229 Laos Attapeu LA 300 M 10 NA 36 90432 336 90768LA001-005 189233 Laos Attapeu LA 300 M 12 NA 36 45216 0 45216LA001-006 189238 Laos Attapeu LA 500 M 42 NA 40 20096 0 20096LA001-007 189243 Laos Attapeu LA 300 M 6 NA 30 52752 0 52752LA001-008 189312 Laos Attapeu LA 500 M 16 NA 38 52501 0 52501LA001-009 189338 Laos Attapeu LA 500 M 25 NA 38 71592 0 71592LA001-010 189344 Laos Attapeu LA 500 F 14 NA 33 24869 0 24869LA001-011 189348 Laos Attapeu LA 300 F 12 NA 40 165792 0 165792LA001-012 189352 Laos Attapeu LA 500 F 26 NA 42 36926 0 36926LA001-013 189360 Laos Attapeu LA 500 F 13 NA 45 28260 0 28260LA001-015 189363 Laos Attapeu LA 500 M 43 NA 39 53882 0 53882

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Hb (g/dL) Hct (%)


gam. count


LA001-016 189365 Laos Attapeu LA 500 M 60 NA 43 16202 0 16202LA001-018 189380 Laos Attapeu LA 300 M 13 NA 31 27255 0 27255LA001-019 189388 Laos Attapeu LA 500 M 13 NA 42 26376 0 26376LA001-020 189390 Laos Attapeu LA 500 F 11 NA 30 18840 304 19144LA001-022 189396 Laos Attapeu LA 500 F 53 NA 35 21980 0 21980LA001-023 189401 Laos Attapeu LA 300 M 7 NA 40 65312 0 65312LA001-024 189407 Laos Attapeu LA 500 M 27 NA 41 25748 16 25764LA001-034 199975 Laos Attapeu LA 500 M 23 NA 38 14318 16 14334LA001-038 199891 Laos Attapeu LA 300 F 10 NA 35 145068 0 145068LA001-041 199910 Laos Attapeu LA 500 F 11 NA 33 33158 0 33158LA001-042 199911 Laos Attapeu LA 500 M 24 NA 44 66317 0 66317LA001-043 199926 Laos Attapeu LA 500 M 35 NA 45 33912 0 33912LA001-044 199927 Laos Attapeu LA 500 M 37 NA 31 198574 0 198574LA001-045 199928 Laos Attapeu LA 500 F 19 NA 35 30772 0 30772LA001-046 199929 Laos Attapeu LA 500 M 38 NA 37 74355 0 74355LA001-047 199934 Laos Attapeu LA 500 M 28 NA 40 80384 0 80384LA001-049 199943 Laos Attapeu LA 500 M 9 NA 35 118692 0 118692LA001-050 199948 Laos Attapeu LA 500 M 7 NA 36 90432 0 90432LA001-051 199954 Laos Attapeu LA 300 F 10 NA 40 115552 0 115552LA001-052 199955 Laos Attapeu LA 500 F 23 NA 41 46346 0 46346LA001-062 199962 Laos Attapeu LA 500 M 40 NA 40 20096 0 20096LA001-063 199966 Laos Attapeu LA 300 M 12 NA 40 105504 32 105536LA001-064 199971 Laos Attapeu LA 500 M 35 NA 41 72094 0 72094LA001-065 200185 Laos Attapeu LA 500 F 11 NA 36 113040 0 113040LA001-066 200191 Laos Attapeu LA 500 F 16 NA 34 38434 0 38434LA001-068 200198 Laos Attapeu LA 500 M 18 NA 39 58781 0 58781LA001-069 200203 Laos Attapeu LA 500 M 30 NA 43 75611 0 75611LA001-070 200213 Laos Attapeu LA 500 M 29 NA 39 39187 0 39187LA001-071 200208 Laos Attapeu LA 500 M 37 NA 40 35168 0 35168LA001-072 200218 Laos Attapeu LA 500 M 28 NA 40 30144 0 30144LA001-073 200226 Laos Attapeu LA 300 F 7 NA 30 33912 0 33912LA001-074 200229 Laos Attapeu LA 500 M 23 NA 37 13942 0 13942LA001-075 200236 Laos Attapeu LA 500 F 20 NA 37 51119 240 51359LA001-076 200337 Laos Attapeu LA 500 M 26 NA 43 91814 0 91814LA001-077 200088 Laos Attapeu LA 500 M 24 NA 36 122083 0 122083LA001-078 200092 Laos Attapeu LA 500 M 22 NA 45 90432 0 90432LA001-079 200097 Laos Attapeu LA 500 F 21 NA 40 45216 0 45216LA001-080 200103 Laos Attapeu LA 500 M 34 NA 37 148710 0 148710LA001-081 200108 Laos Attapeu LA 500 M 35 NA 45 197820 0 197820LA001-082 200113 Laos Attapeu LA 500 M 26 NA 40 85408 0 85408

Page 16 of 135


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Hb (g/dL) Hct (%)


gam. count


LA001-083 200116 Laos Attapeu LA 500 M 29 NA 53 66568 0 66568LA001-084 200122 Laos Attapeu LA 500 M 23 NA 40 30144 0 30144LA001-085 200125 Laos Attapeu LA 500 M 20 NA 45 96084 0 96084LA001-086 200384 Laos Attapeu LA 500 M 26 NA 40 50240 0 50240LA001-091 200137 Laos Attapeu LA 500 F 37 NA 41 15449 0 15449LA001-092 200141 Laos Attapeu LA 300 F 13 NA 32 36173 0 36173LA001-093 200144 Laos Attapeu LA 500 M 21 NA 38 62046 0 62046LA001-094 200151 Laos Attapeu LA 300 M 7 NA 31 101234 0 101234LA001-095 200157 Laos Attapeu LA 300 M 14 NA 36 117562 0 117562LA001-096 200160 Laos Attapeu LA 500 M 27 NA 45 22608 0 22608LA001-097 200165 Laos Attapeu LA 500 F 17 NA 35 13188 0 13188LA001-098 200169 Laos Attapeu LA 300 M 13 NA 35 131880 0 131880LA001-099 200170 Laos Attapeu LA 500 F 19 NA 39 34289 0 34289LA001-100 200171 Laos Attapeu LA 500 M 24 NA 38 28637 0 28637LA001-101 200172 Laos Attapeu LA 300 M 12 NA 35 167048 0 167048LA001-102 217666 Laos Attapeu LA 500 F 18 NA 31 27255 0 27255LA001-103 217676 Laos Attapeu LA 500 M 26 NA 37 46472 0 46472LA001-105 217679 Laos Attapeu LA 500 F 47 NA 38 28637 0 28637LA001-106 217684 Laos Attapeu LA 500 F 40 NA 40 10048 0 10048LA001-107 217689 Laos Attapeu LA 500 M 23 NA 37 130122 0 130122LA001-108 217691 Laos Attapeu LA 500 F 34 NA 38 52501 0 52501LA001-109 217696 Laos Attapeu LA 500 M 18 NA 35 197820 0 197820LA001-110 217701 Laos Attapeu LA 300 M 14 NA 35 17584 0 17584LA001-111 217706 Laos Attapeu LA 500 M 27 NA 40 175840 0 175840LA001-112 199992 Laos Attapeu LA 500 M 18 NA 40 55264 0 55264LA001-113 199999 Laos Attapeu LA 300 M 15 NA 41 15449 0 15449LA001-114 200006 Laos Attapeu LA 300 M 15 NA 42 15826 0 15826LA001-115 199996 Laos Attapeu LA 500 M 23 NA 42 68578 0 68578LA001-116 200010 Laos Attapeu LA 500 M 23 NA 42 36926 0 36926LA001-117 200023 Laos Attapeu LA 500 M 27 NA 41 51496 0 51496LA001-118 200020 Laos Attapeu LA 500 F 30 NA 41 30898 0 30898LA001-119 200017 Laos Attapeu LA 500 M 30 NA 38 181366 0 181366LA001-120 200032 Laos Attapeu LA 500 M 24 NA 35 87920 0 87920MM001-001 210552 Myanmar Shwe Kyin MM 500 F 20 NA 33 302570 0 302570MM001-002 210570 Myanmar Shwe Kyin MM 500 M 42 NA 41 175086 0 175086MM001-003 210579 Myanmar Shwe Kyin MM 500 M 46 NA 44 420006 0 420006MM001-004 210609 Myanmar Shwe Kyin MM 500 M 19 NA 38 190912 0 190912MM001-005 210248 Myanmar Shwe Kyin MM 500 M 18 NA 39 83273 0 83273MM001-005 210634 Myanmar Shwe Kyin MM 500 M 18 NA 39 83273 0 83273MM001-006 210247 Myanmar Shwe Kyin MM 500 M 51 NA 42 73853 0 73853

Page 17 of 135


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color



Hb (g/dL) Hct (%)


gam. count


MM001-006 210635 Myanmar Shwe Kyin MM 500 M 51 NA 42 73853 0 73853MM001-007 210268 Myanmar Shwe Kyin MM 500 F 31 NA 45 101736 0 101736MM001-008 210292 Myanmar Shwe Kyin MM 500 F 28 NA 41 242031 0 242031MM001-009 210293 Myanmar Shwe Kyin MM 500 M 42 NA 34 38434 0 38434MM001-010 209962 Myanmar Shwe Kyin MM 500 M 18 NA 34 81138 0 81138MM001-011 210452 Myanmar Shwe Kyin MM 500 F 31 NA 27 162778 0 162778MM001-012 210464 Myanmar Shwe Kyin MM 500 F 13 NA 26 26125 176 26301MM001-013 210204 Myanmar Shwe Kyin MM 500 F 20 NA 29 47351 0 47351MM001-014 210473 Myanmar Shwe Kyin MM 500 M 30 NA 40 75360 0 75360MM001-015 210053 Myanmar Shwe Kyin MM 500 M 26 NA 43 205230 0 205230MM001-016 210216 Myanmar Shwe Kyin MM 500 M 31 NA 41 61795 0 61795MM001-017 210406 Myanmar Shwe Kyin MM 500 M 26 NA 42 31651 0 31651MM001-018 210485 Myanmar Shwe Kyin MM 500 F 28 NA 27 61042 0 61042MM001-019 210536 Myanmar Shwe Kyin MM 500 M 32 NA 40 140672 0 140672MM001-020 210233 Myanmar Shwe Kyin MM 500 M 23 NA 34 222061 0 222061MM001-021 210849 Myanmar Shwe Kyin MM 500 M 20 NA 43 108016 0 108016MM001-022 210850 Myanmar Shwe Kyin MM 500 F 17 NA 40 115552 0 115552MM001-023 210898 Myanmar Shwe Kyin MM 500 M 18 NA 41 205984 0 205984MM001-024 210906 Myanmar Shwe Kyin MM 500 M 54 NA 37 213771 0 213771MM001-025 210919 Myanmar Shwe Kyin MM 500 M 18 NA 40 190912 20096 211008MM001-026 210930 Myanmar Shwe Kyin MM 500 M 38 NA 32 136653 0 136653MM001-027 209977 Myanmar Shwe Kyin MM 500 M 24 NA 42 47477 0 47477MM001-028 209995 Myanmar Shwe Kyin MM 500 M 19 NA 39 19594 0 19594MM001-029 209996 Myanmar Shwe Kyin MM 500 M 50 NA 30 71592 0 71592MM001-030 210013 Myanmar Shwe Kyin MM 500 M 36 NA 45 45216 0 45216MM001-031 210820 Myanmar Shwe Kyin MM 500 M 20 NA 39 24492 4898 29390MM001-032 210821 Myanmar Shwe Kyin MM 500 M 25 NA 41 41197 5150 46346MM001-033 210414 Myanmar Shwe Kyin MM 500 M 17 NA 41 36047 0 36047MM001-034 210436 Myanmar Shwe Kyin MM 500 F 50 NA 40 25120 0 25120MM001-035 210437 Myanmar Shwe Kyin MM 500 M 25 NA 42 11568 0 11568MM001-036 210073 Myanmar Shwe Kyin MM 500 F 19 NA 31 89553 0 89553MM001-037 210105 Myanmar Shwe Kyin MM 500 M 18 NA 37 46472 0 46472MM001-038 219988 Myanmar Shwe Kyin MM 500 F 21 NA 43 70210 0 70210MM001-039 220001 Myanmar Shwe Kyin MM 500 M 40 NA 35 101108 0 101108MM001-040 220027 Myanmar Shwe Kyin MM 500 M 19 NA 39 48984 0 48984MM001-041 210654 Myanmar Shwe Kyin MM 500 M 29 NA 39 78374 0 78374MM001-042 210666 Myanmar Shwe Kyin MM 500 M 18 NA 36 63302 0 63302MM001-043 220297 Myanmar Shwe Kyin MM 500 M 16 NA 34 17920 0 17920MM001-044 220361 Myanmar Shwe Kyin MM 500 M 18 NA 36 21280 16 21296MM001-045 220374 Myanmar Shwe Kyin MM 500 F 24 NA 44 149213 0 149213

Page 18 of 135


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color



Hb (g/dL) Hct (%)


gam. count


MM001-046 220086 Myanmar Shwe Kyin MM 500 M 34 NA 40 12112 0 12112MM001-047 220142 Myanmar Shwe Kyin MM 500 M 18 NA 34 51245 0 51245MM001-048 220154 Myanmar Shwe Kyin MM 500 M 45 NA 27 30521 0 30521MM001-049 220167 Myanmar Shwe Kyin MM 500 M 32 NA 30 184632 0 184632MM001-050 220179 Myanmar Shwe Kyin MM 500 M 20 NA 30 211008 0 211008MM001-051 220192 Myanmar Shwe Kyin MM 500 F 51 NA 27 29216 0 29216MM001-052 220204 Myanmar Shwe Kyin MM 500 M 26 NA 36 176342 0 176342MM001-053 220216 Myanmar Shwe Kyin MM 500 M 25 NA 43 97214 0 97214MM001-054 220387 Myanmar Shwe Kyin MM 500 M 24 NA 45 11776 0 11776MM001-055 220420 Myanmar Shwe Kyin MM 500 M 23 NA 40 23824 0 23824MM001-056 220431 Myanmar Shwe Kyin MM 500 M 33 NA 38 12736 0 12736MM001-057 220468 Myanmar Shwe Kyin MM 500 M 22 NA 53 15088 0 15088MM001-058 220475 Myanmar Shwe Kyin MM 500 M 38 NA 32 64307 4019 68326MM001-059 239513 Myanmar Shwe Kyin MM 500 M 25 NA 45 15616 0 15616MM001-060 239621 Myanmar Shwe Kyin MM 500 M 21 NA 37 17312 0 17312MM001-061 239608 Myanmar Shwe Kyin MM 500 M 18 NA 40 195936 0 195936MM001-062 239568 Myanmar Shwe Kyin MM 500 M 21 NA 41 61795 0 61795MM001-063 239538 Myanmar Shwe Kyin MM 500 M 18 NA 45 67824 0 67824MM001-064 239536 Myanmar Shwe Kyin MM 500 M 28 NA 44 60790 0 60790MM001-065 239532 Myanmar Shwe Kyin MM 500 M 18 NA 40 24592 0 24592MM001-066 239872 Myanmar Shwe Kyin MM 500 M 53 NA 44 26944 0 26944MM001-067 239862 Myanmar Shwe Kyin MM 500 M 27 NA 50 106760 0 106760MM001-068 239842 Myanmar Shwe Kyin MM 500 M 25 NA 43 11504 0 11504MM001-069 239841 Myanmar Shwe Kyin MM 500 F 18 NA 30 75360 0 75360MM001-070 239803 Myanmar Shwe Kyin MM 500 M 38 NA 43 23200 32 23232MM001-071 239791 Myanmar Shwe Kyin MM 500 M 25 NA 45 163908 0 163908MM001-072 239781 Myanmar Shwe Kyin MM 500 M 25 NA 44 138160 0 138160MM001-073 239769 Myanmar Shwe Kyin MM 500 M 18 NA 44 44211 0 44211MM001-074 239719 Myanmar Shwe Kyin MM 500 M 18 NA 34 25622 0 25622MM001-075 239706 Myanmar Shwe Kyin MM 500 M 24 NA 33 70462 4145 74606MM001-076 238755 Myanmar Shwe Kyin MM 500 M 23 NA 43 91814 0 91814MM001-077 238774 Myanmar Shwe Kyin MM 500 M 18 NA 38 85910 0 85910MM001-078 238800 Myanmar Shwe Kyin MM 500 M 35 NA 44 93949 0 93949MM001-079 238813 Myanmar Shwe Kyin MM 500 M 22 NA 46 10640 0 10640MM001-080 238824 Myanmar Shwe Kyin MM 500 M 19 NA 40 27088 16 27104TH004-001 188821 Thailand Mae Sot TH4 500 M 23 14.6 43 27004 0 27004TH004-002 188831 Thailand Mae Sot TH4 500 M 23 8.8 30 30144 160 30304TH004-003 188839 Thailand Mae Sot TH4 500 M 27 12.9 42 42202 0 42202TH004-004 188843 Thailand Mae Sot TH4 500 M 35 12.8 43 43206 0 43206TH004-005 188849 Thailand Mae Sot TH4 500 M 26 9.6 31 23362 240 23602

Page 19 of 135


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color



Hb (g/dL) Hct (%)


gam. count


TH004-006 188854 Thailand Mae Sot TH4 500 M 18 14.4 50 18840 0 18840TH004-007 188859 Thailand Mae Sot TH4 500 M 45 14.2 44 82896 0 82896TH004-008 188864 Thailand Mae Sot TH4 500 M 51 13 43 9168 0 9168TH004-009 189022 Thailand Mae Sot TH4 500 M 25 13.1 46 57776 0 57776TH004-010 189017 Thailand Mae Sot TH4 500 M 19 13.9 42 263760 0 263760TH004-011 189014 Thailand Mae Sot TH4 500 M 30 12.8 43 37806 0 37806TH004-012 188909 Thailand Mae Sot TH4 500 F 18 11.6 35 189028 0 189028TH004-013 193160 Thailand Mae Sot TH4 500 M 41 13.2 43 16202 0 16202TH004-014 193059 Thailand Mae Sot TH4 500 M 18 13.3 42 137155 0 137155TH004-015 193064 Thailand Mae Sot TH4 500 M 27 11.5 42 327062 0 327062TH004-016 193071 Thailand Mae Sot TH4 500 M 27 12.3 42 10550 0 10550TH004-017 193072 Thailand Mae Sot TH4 500 M 18 13.3 45 2560 0 2560TH004-018 193080 Thailand Mae Sot TH4 500 M 30 15.6 50 62800 0 62800TH004-019 197292 Thailand Mae Sot TH4 500 M 20 12.1 40 10048 0 10048TH004-020 197303 Thailand Mae Sot TH4 500 M 26 11 38 109774 0 109774TH004-021 197308 Thailand Mae Sot TH4 500 M 37 14.2 46 28888 0 28888TH004-022 197493 Thailand Mae Sot TH4 500 M 30 8.5 30 60288 0 60288TH004-023 197312 Thailand Mae Sot TH4 500 F 20 11.2 35 8792 0 8792TH004-024 197329 Thailand Mae Sot TH4 500 M 27 12.3 48 192922 0 192922TH004-025 197513 Thailand Mae Sot TH4 500 M 26 13 43 59409 0 59409TH004-026 197512 Thailand Mae Sot TH4 500 M 23 13.9 43 81012 0 81012TH004-027 197526 Thailand Mae Sot TH4 500 M 46 8.8 28 28134 1344 29478TH004-028 197533 Thailand Mae Sot TH4 500 M 30 11.8 35 8792 0 8792TH004-028 197344 Thailand Mae Sot TH4 300 M 30 11.8 35 8792 0 8792TH004-029 197536 Thailand Mae Sot TH4 500 M 18 11.6 41 46346 0 46346TH004-029 197540 Thailand Mae Sot TH4 500 M 18 11.6 41 46346 0 46346TH004-030 197381 Thailand Mae Sot TH4 500 M 23 13.7 42 15826 0 15826TH004-031 197376 Thailand Mae Sot TH4 500 M 29 14.4 42 10550 0 10550TH004-032 197364 Thailand Mae Sot TH4 500 F 21 10.6 32 16077 0 16077TH004-033 197363 Thailand Mae Sot TH4 500 M 29 13.6 30 7536 0 7536TH004-034 197555 Thailand Mae Sot TH4 500 M 40 14.7 NA NA NA NATH004-035 197349 Thailand Mae Sot TH4 500 M 23 8.8 28 38685 0 38685TH004-036 197356 Thailand Mae Sot TH4 500 M 21 14.2 43 43206 0 43206TH004-037 197580 Thailand Mae Sot TH4 500 M 33 11 41 30898 0 30898TH004-038 197582 Thailand Mae Sot TH4 500 M 28 13.1 41 108142 0 108142TH004-039 197583 Thailand Mae Sot TH4 500 M 22 16.1 50 100480 0 100480TH004-040 197569 Thailand Mae Sot TH4 500 M 46 13.8 41 41197 0 41197TH004-041 206948 Thailand Mae Sot TH4 500 M 33 13.8 43 10802 0 10802TH004-042 206949 Thailand Mae Sot TH4 500 M 34 15.6 45 56520 0 56520TH004-044 206972 Thailand Mae Sot TH4 500 F 29 9.3 27 27130 192 27322

Page 20 of 135


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color



Hb (g/dL) Hct (%)


gam. count


TH004-046 207000 Thailand Mae Sot TH4 500 M 18 13.3 39 29390 0 29390TH004-047 207002 Thailand Mae Sot TH4 500 M 26 14.9 46 46221 0 46221TH004-048 207007 Thailand Mae Sot TH4 500 F 18 8.2 22 22106 0 22106TH004-049 207012 Thailand Mae Sot TH4 500 M 20 13.1 47 17710 0 17710TH004-050 207017 Thailand Mae Sot TH4 500 F 28 12.2 39 205733 0 205733TH004-051 207022 Thailand Mae Sot TH4 500 F 48 9.1 36 27130 0 27130TH004-052 207027 Thailand Mae Sot TH4 500 M 24 12.7 39 44086 0 44086TH004-053 208839 Thailand Mae Sot TH4 500 F 39 14.6 43 27004 0 27004TH004-054 208841 Thailand Mae Sot TH4 500 M 48 10.6 33 8290 0 8290TH004-055 208848 Thailand Mae Sot TH4 500 F 33 10.5 27 33912 48 33960TH004-056 208844 Thailand Mae Sot TH4 500 F 37 9.4 28 70336 0 70336TH004-057 208875 Thailand Mae Sot TH4 500 M 26 15.4 46 109774 0 109774TH004-058 208876 Thailand Mae Sot TH4 500 M 26 15.8 48 108518 0 108518TH004-059 208881 Thailand Mae Sot TH4 500 M 35 14.2 49 36926 0 36926TH004-060 208879 Thailand Mae Sot TH4 500 M 35 12.2 39 3616 0 3616TH004-061 208891 Thailand Mae Sot TH4 500 F 40 9 28 101987 16 102003TH004-062 208906 Thailand Mae Sot TH4 500 M 58 15.1 48 78374 0 78374TH004-063 208901 Thailand Mae Sot TH4 500 M 30 11.2 35 21980 0 21980TH004-064 208921 Thailand Mae Sot TH4 500 M 35 14.5 38 19091 0 19091TH004-065 208935 Thailand Mae Sot TH4 500 M 21 12.4 39 83273 32 83305TH004-066 210947 Thailand Mae Sot TH4 500 M 33 10.4 38 109774 0 109774TH004-067 210953 Thailand Mae Sot TH4 500 F 48 8.5 27 13565 0 13565TH004-068 210955 Thailand Mae Sot TH4 500 M 25 13.9 41 92693 0 92693TH004-069 210962 Thailand Mae Sot TH4 500 M 31 15.2 46 103997 0 103997TH004-070 210968 Thailand Mae Sot TH4 500 M 24 14.2 42 73853 0 73853TH004-071 210972 Thailand Mae Sot TH4 500 M 30 13.8 47 100354 0 100354TH004-072 210978 Thailand Mae Sot TH4 500 F 30 12.3 37 88297 0 88297TH004-073 193097 Thailand Mae Sot TH4 500 M 22 13.2 37 23236 0 23236TH004-074 193096 Thailand Mae Sot TH4 500 M 38 15.7 51 51245 0 51245TH004-075 193091 Thailand Mae Sot TH4 500 M 29 14.7 34 17082 0 17082TH004-076 193113 Thailand Mae Sot TH4 500 F 19 9.1 27 33912 0 33912TH004-077 193108 Thailand Mae Sot TH4 500 F 18 12.1 35 17584 0 17584TH004-078 193119 Thailand Mae Sot TH4 500 M 40 14.1 40 135648 0 135648TH004-079 210984 Thailand Mae Sot TH4 500 F 20 13.6 44 292899 16 292915TH004-080 210991 Thailand Mae Sot TH4 500 M 39 13 36 22608 0 22608TH004-081 193085 Thailand Mae Sot TH4 500 F 19 12 37 37178 0 37178TH004-082 197297 Thailand Mae Sot TH4 500 M 32 11.5 43 48607 0 48607TH004-083 197316 Thailand Mae Sot TH4 500 M 20 14.9 47 4544 0 4544TH004-084 197322 Thailand Mae Sot TH4 500 F 22 7.3 18 27130 80 27210TH004-085 197323 Thailand Mae Sot TH4 500 F 36 8.1 21 7913 0 7913

Page 21 of 135


Field site

color



Hb (g/dL) Hct (%)


gam. count


TH004-086 197519 Thailand Mae Sot TH4 500 M 42 13.4 46 57776 0 57776TH004-086 197516 Thailand Mae Sot TH4 500 M 42 13.4 46 57776 0 57776TH004-087 197333 Thailand Mae Sot TH4 500 M 25 15.1 47 29516 0 29516TH004-087 197337 Thailand Mae Sot TH4 500 M 25 15.1 47 29516 0 29516TH004-088 197341 Thailand Mae Sot TH4 500 M 19 12.9 39 24492 32 24524TH004-088 197522 Thailand Mae Sot TH4 500 M 19 12.9 39 24492 32 24524TH004-089 197386 Thailand Mae Sot TH4 500 M 25 13.6 43 5792 0 5792TH004-089 197384 Thailand Mae Sot TH4 500 M 25 13.6 43 5792 0 5792TH004-090 197545 Thailand Mae Sot TH4 500 M 31 11.8 38 229094 0 229094TH004-091 197346 Thailand Mae Sot TH4 500 M 28 10.2 31 7787 0 7787TH004-092 197552 Thailand Mae Sot TH4 500 F 36 12.1 34 132382 0 132382TH004-093 197369 Thailand Mae Sot TH4 500 M 26 14.3 43 545481 0 545481TH004-094 197560 Thailand Mae Sot TH4 500 M 50 16.3 48 12058 0 12058TH004-095 197581 Thailand Mae Sot TH4 500 F 51 12.1 41 20598 0 20598TH004-096 206945 Thailand Mae Sot TH4 500 M 20 14.4 45 118692 16 118708TH004-097 206962 Thailand Mae Sot TH4 500 F 32 14.6 42 47477 0 47477TH004-098 206967 Thailand Mae Sot TH4 500 M 20 16.4 48 30144 0 30144TH004-099 206982 Thailand Mae Sot TH4 500 M 48 12.8 42 73853 0 73853TH004-101 206984 Thailand Mae Sot TH4 500 M 38 12.5 37 41825 0 41825TH004-102 208852 Thailand Mae Sot TH4 500 M 46 14.2 42 6688 0 6688TH004-103 208858 Thailand Mae Sot TH4 500 M 21 15.2 48 24115 0 24115TH004-104 208866 Thailand Mae Sot TH4 500 M 33 14.7 43 5401 0 5401TH004-105 208886 Thailand Mae Sot TH4 500 M 18 14.3 37 13942 0 13942TH004-106 208912 Thailand Mae Sot TH4 500 F 31 12.6 37 106886 0 106886TH004-107 208915 Thailand Mae Sot TH4 500 M 53 12.7 38 14318 0 14318TH004-108 208925 Thailand Mae Sot TH4 500 F 57 12.9 39 24492 0 24492TH004-110 193135 Thailand Mae Sot TH4 500 M 38 13.5 44 22106 0 22106TH004-111 211030 Thailand Mae Sot TH4 500 F 44 13.6 42 36926 0 36926TH004-112 211025 Thailand Mae Sot TH4 500 M 47 15.1 45 118692 0 118692TH004-113 211019 Thailand Mae Sot TH4 500 M 18 9 28 84403 3552 87955TH004-114 211011 Thailand Mae Sot TH4 500 M 37 13.6 37 6272 0 6272TH004-115 193123 Thailand Mae Sot TH4 500 M 37 13 40 40192 0 40192TH004-116 193130 Thailand Mae Sot TH4 500 M 46 12.4 42 42202 0 42202TH004-117 210995 Thailand Mae Sot TH4 500 M 22 15.5 46 86664 0 86664TH004-118 193149 Thailand Mae Sot TH4 500 F 21 11.3 38 71592 0 71592TH004-120 193154 Thailand Mae Sot TH4 500 M 30 13.8 47 153483 0 153483TH005-001 205246 Thailand Sisakhet TH5 500 M 45 12.1 34 12811 0 12811TH005-002 205269 Thailand Sisakhet TH5 500 M 44 12.9 39 24492 0 24492TH005-003 205290 Thailand Sisakhet TH5 500 M 45 14.6 47 141677 0 141677TH005-004 205312 Thailand Sisakhet TH5 500 M 40 8.8 26 13062 0 13062

Page 22 of 135


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color



Hb (g/dL) Hct (%)


gam. count


TH005-005 205327 Thailand Sisakhet TH5 500 M 31 8.5 22 41448 0 41448TH005-006 205341 Thailand Sisakhet TH5 500 M 23 14.2 43 75611 0 75611TH005-007 205374 Thailand Sisakhet TH5 500 M 40 12.4 40 50240 0 50240TH005-008 205394 Thailand Sisakhet TH5 500 M 16 14.4 44 132634 0 132634TH005-009 205413 Thailand Sisakhet TH5 500 M 22 12.5 49 55390 0 55390TH005-010 205441 Thailand Sisakhet TH5 500 M 46 10.9 34.6 4346 384 4730TH005-011 205484 Thailand Sisakhet TH5 500 M 37 12.6 39.4 192997 0 192997TH005-012 205522 Thailand Sisakhet TH5 500 M 23 13.8 45 79128 0 79128TH005-013 205507 Thailand Sisakhet TH5 500 M 48 12.5 35.1 83763 0 83763TH005-014 205548 Thailand Sisakhet TH5 500 M 29 17.1 48.5 18275 0 18275TH005-015 205457 Thailand Sisakhet TH5 500 M 25 15.5 50 75360 0 75360TH005-017 205595 Thailand Sisakhet TH5 500 M 19 12.4 40 40192 0 40192TH005-018 232082 Thailand Sisakhet TH5 500 M 22 15.5 51 12811 0 12811TH005-020 232111 Thailand Sisakhet TH5 500 M 52 14.5 45.5 11430 0 11430TH005-021 205606 Thailand Sisakhet TH5 500 M 30 12.4 45 22608 0 22608TH005-022 232257 Thailand Sisakhet TH5 300 M 21 12.8 35 13188 0 13188TH005-023 205621 Thailand Sisakhet TH5 500 M 31 14.8 44 11053 0 11053TH005-024 205715 Thailand Sisakhet TH5 500 M 31 14.5 43.5 10927 0 10927TH005-025 232303 Thailand Sisakhet TH5 500 M 38 13.6 46 75109 0 75109TH005-026 232329 Thailand Sisakhet TH5 500 M 54 13.4 41.5 161584 0 161584TH005-027 232360 Thailand Sisakhet TH5 500 M 22 14.8 45.5 40004 0 40004TH005-028 232387 Thailand Sisakhet TH5 500 M 27 12.7 38 19091 0 19091TH005-029 232403 Thailand Sisakhet TH5 500 M 23 13.6 43.5 10927 0 10927TH006-002 204865 Thailand Khun Han TH6 500 M 33 13.7 40 135648 0 135648TH006-003 204875 Thailand Khun Han TH6 500 M 18 12.3 34 29893 0 29893TH006-004 204900 Thailand Khun Han TH6 500 M 22 13.6 44 16579 0 16579TH006-006 204935 Thailand Khun Han TH6 500 M 21 13.7 44 11053 0 11053TH006-007 204951 Thailand Khun Han TH6 500 M 37 15 35 26376 0 26376TH006-009 205020 Thailand Khun Han TH6 500 M 21 14.6 46 23110 0 23110TH006-010 205024 Thailand Khun Han TH6 500 M 22 13.2 56 49235 0 49235TH006-011 205038 Thailand Khun Han TH6 500 M 22 14.2 45 33912 0 33912TH006-012 205052 Thailand Khun Han TH6 500 M 43 14.2 44 64 0 64TH007-001 205750 Thailand Ranong TH7 500 M 27 13 43 37806 0 37806TH007-002 205780 Thailand Ranong TH7 500 M 47 14.7 40 15072 0 15072TH007-003 205782 Thailand Ranong TH7 500 F 38 13.2 40 25120 0 25120TH007-004 205798 Thailand Ranong TH7 500 M 36 15.6 49 24618 0 24618TH007-005 205814 Thailand Ranong TH7 500 M 25 12.6 40 40192 0 40192TH007-006 205959 Thailand Ranong TH7 500 M 30 13.3 43 81012 0 81012TH007-007 205981 Thailand Ranong TH7 500 F 47 15.5 49 12309 0 12309TH007-008 205996 Thailand Ranong TH7 500 M 26 13.1 44 27632 0 27632

Page 23 of 135


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color



Hb (g/dL) Hct (%)


gam. count


TH007-009 206020 Thailand Ranong TH7 500 M 30 12.7 38.5 33849 0 33849TH007-010 205848 Thailand Ranong TH7 500 M 33 10.1 32 20096 0 20096TH007-011 205880 Thailand Ranong TH7 500 F 44 12.4 37 92944 0 92944TH007-012 205901 Thailand Ranong TH7 500 M 31 14.4 44 77370 0 77370TH007-013 206041 Thailand Ranong TH7 500 M 53 10.9 40 55264 0 55264TH007-014 206048 Thailand Ranong TH7 500 F 25 12 43 91814 0 91814TH007-015 206084 Thailand Ranong TH7 500 M 19 11 37 51119 0 51119TH007-016 206108 Thailand Ranong TH7 500 M 23 13.6 47 94451 0 94451TH007-018 206155 Thailand Ranong TH7 500 M 39 11.9 43 86413 0 86413TH007-019 206176 Thailand Ranong TH7 500 F 27 10.9 36 58781 0 58781TH007-020 206212 Thailand Ranong TH7 500 M 33 12.2 40 80384 0 80384TH007-021 206233 Thailand Ranong TH7 500 F 39 11.3 34 8541 0 8541TH007-023 227923 Thailand Ranong TH7 500 M 26 13.6 43 70210 0 70210VN001-001 182620 Vietnam Binh Phuoc VN 500 M 17 11.1 33 53882 256 54138VN001-002 182640 Vietnam Binh Phuoc VN 500 M 15 13.8 40 75360 0 75360VN001-003 182660 Vietnam Binh Phuoc VN 500 M 27 13 40 60288 0 60288VN001-004 182680 Vietnam Binh Phuoc VN 500 M 43 14.3 42 15826 0 15826VN001-005 182700 Vietnam Binh Phuoc VN 500 M 23 17.7 47 41322 0 41322VN001-006 182720 Vietnam Binh Phuoc VN 500 M 27 14.3 46 46221 0 46221VN001-007 182740 Vietnam Binh Phuoc VN 500 M 14 12.4 37 23236 0 23236VN001-008 182760 Vietnam Binh Phuoc VN 500 F 14 13.2 38 66819 0 66819VN001-009 182780 Vietnam Binh Phuoc VN 500 M 25 14.5 41 30898 0 30898VN001-010 182800 Vietnam Binh Phuoc VN 500 M 19 13.1 37 13942 0 13942VN001-011 182672 Vietnam Binh Phuoc VN 500 M 31 15.9 45 22608 0 22608VN001-012 182676 Vietnam Binh Phuoc VN 300 M 35 15.1 44 49738 0 49738VN001-013 182692 Vietnam Binh Phuoc VN 500 F 36 12.8 36 67824 0 67824VN001-014 182696 Vietnam Binh Phuoc VN 500 M 23 12.9 35 26376 0 26376VN001-015 182772 Vietnam Binh Phuoc VN 500 M 15 10.3 33 49738 576 50314VN001-016 182776 Vietnam Binh Phuoc VN 500 M 16 11 38 66819 0 66819VN001-017 194963 Vietnam Binh Phuoc VN 500 M 55 12.4 35 17584 0 17584VN001-018 194968 Vietnam Binh Phuoc VN 500 M 21 13.7 41 56646 0 56646VN001-019 194970 Vietnam Binh Phuoc VN 500 M 19 13.3 38 14318 0 14318VN001-021 194976 Vietnam Binh Phuoc VN 500 M 46 14.9 45 62172 0 62172VN001-022 194980 Vietnam Binh Phuoc VN 500 M 37 13.2 40 40192 0 40192VN001-023 194984 Vietnam Binh Phuoc VN 500 M 38 15.4 46 51998 0 51998VN001-024 194988 Vietnam Binh Phuoc VN 300 M 5 8.7 30 15072 0 15072VN001-025 194992 Vietnam Binh Phuoc VN 500 M 27 14.4 43 102615 0 102615VN001-026 194996 Vietnam Binh Phuoc VN 500 M 27 13.4 38 23864 0 23864VN001-027 195000 Vietnam Binh Phuoc VN 300 F 3 10 32 84403 0 84403VN001-028 195004 Vietnam Binh Phuoc VN 500 M 30 15.6 45 96084 0 96084

Page 24 of 135


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Hb (g/dL) Hct (%)


gam. count


VN001-029 195012 Vietnam Binh Phuoc VN 500 F 28 16.3 45 169560 0 169560VN001-030 195016 Vietnam Binh Phuoc VN 500 M 58 17.5 45 16956 0 16956VN001-031 195008 Vietnam Binh Phuoc VN 500 M 15 15.7 44 49738 0 49738VN001-032 195020 Vietnam Binh Phuoc VN 500 M 43 17 45 101736 0 101736VN001-033 195024 Vietnam Binh Phuoc VN 500 M 11 12.6 38 57274 0 57274VN001-034 195028 Vietnam Binh Phuoc VN 500 M 31 16.2 45 16956 0 16956VN001-035 195032 Vietnam Binh Phuoc VN 500 M 45 13.2 34 17082 0 17082VN001-036 195036 Vietnam Binh Phuoc VN 500 M 24 15.5 38 23864 0 23864VN001-037 195040 Vietnam Binh Phuoc VN 500 M 23 15.8 44 138160 0 138160VN001-038 195044 Vietnam Binh Phuoc VN 500 M 47 15.4 40 85408 0 85408VN001-039 195048 Vietnam Binh Phuoc VN 500 M 45 16.8 45 62172 0 62172VN001-040 195052 Vietnam Binh Phuoc VN 500 M 25 17.6 47 29516 0 29516VN001-041 195056 Vietnam Binh Phuoc VN 300 M 9 11.9 35 105504 0 105504VN001-042 195060 Vietnam Binh Phuoc VN 500 F 52 15 43 135020 0 135020VN001-045 203929 Vietnam Binh Phuoc VN 500 M 35 16.8 46 98219 0 98219VN001-046 203933 Vietnam Binh Phuoc VN 500 M 14 14.2 42 84403 0 84403VN001-047 203937 Vietnam Binh Phuoc VN 500 F 36 15.7 45 56520 0 56520VN001-048 203941 Vietnam Binh Phuoc VN 500 F 38 13 39 48984 0 48984VN001-049 203946 Vietnam Binh Phuoc VN 500 M 26 17 42 47477 0 47477VN001-050 203948 Vietnam Binh Phuoc VN 500 M 31 13.7 40 100480 0 100480VN001-051 203953 Vietnam Binh Phuoc VN 500 M 18 15.8 42 163531 0 163531VN001-052 203957 Vietnam Binh Phuoc VN 500 M 52 13.7 41 20598 0 20598VN001-053 204061 Vietnam Binh Phuoc VN 500 M 18 17.1 43 48607 0 48607VN001-054 204097 Vietnam Binh Phuoc VN 500 F 16 13.7 37 139416 0 139416VN001-055 204065 Vietnam Binh Phuoc VN 500 M 40 15.1 42.5 48042 0 48042VN001-056 204069 Vietnam Binh Phuoc VN 500 F 43 12.8 36.5 13753 0 13753VN001-057 204073 Vietnam Binh Phuoc VN 500 M 18 14.7 40.5 183125 0 183125VN001-058 204077 Vietnam Binh Phuoc VN 500 M 21 15.6 44 16579 0 16579VN001-059 204081 Vietnam Binh Phuoc VN 500 M 19 17.7 51 134518 0 134518VN001-060 204085 Vietnam Binh Phuoc VN 500 M 61 12.9 37 18589 0 18589VN001-061 204089 Vietnam Binh Phuoc VN 500 F 39 10.9 34 21352 0 21352VN001-062 204092 Vietnam Binh Phuoc VN 500 M 20 13.6 37 51119 0 51119VN001-063 204101 Vietnam Binh Phuoc VN 500 M 32 13.4 37 153358 0 153358VN001-064 204105 Vietnam Binh Phuoc VN 500 M 29 14.8 41 97842 0 97842VN001-066 204113 Vietnam Binh Phuoc VN 500 F 30 12.5 34 55515 0 55515VN001-067 204117 Vietnam Binh Phuoc VN 500 F 26 10.2 25.7 16140 48 16188VN001-068 204121 Vietnam Binh Phuoc VN 500 M 20 16.7 43 48607 0 48607VN001-069 204125 Vietnam Binh Phuoc VN 500 M 47 15.8 49 73853 0 73853VN001-070 204129 Vietnam Binh Phuoc VN 500 M 40 14.8 43 108016 0 108016VN001-072 204057 Vietnam Binh Phuoc VN 500 F 48 14.1 40 25120 0 25120

Page 25 of 135


Field site

color



Hb (g/dL) Hct (%)


gam. count


VN001-073 214762 Vietnam Binh Phuoc VN 500 M 30 13 38 28637 0 28637VN001-074 214766 Vietnam Binh Phuoc VN 500 M 17 10.8 32 80384 1296 81680VN001-075 214770 Vietnam Binh Phuoc VN 500 M 41 12.2 37 27883 0 27883VN001-076 214774 Vietnam Binh Phuoc VN 500 M 21 15.3 42 31651 0 31651VN001-077 214778 Vietnam Binh Phuoc VN 500 M 17 15.3 48 24115 0 24115VN001-078 214782 Vietnam Binh Phuoc VN 500 M 12 14.6 41 108142 0 108142VN001-079 214786 Vietnam Binh Phuoc VN 500 M 15 16.2 47 165290 0 165290VN001-080 214790 Vietnam Binh Phuoc VN 500 M 39 12.7 37 32530 48 32578VN001-081 214794 Vietnam Binh Phuoc VN 500 M 39 15.8 43 21603 0 21603VN001-082 214798 Vietnam Binh Phuoc VN 500 F 26 14.7 41 15449 0 15449VN001-084 214806 Vietnam Binh Phuoc VN 500 M 43 16.5 47 29516 0 29516VN001-085 214810 Vietnam Binh Phuoc VN 500 M 18 13.4 41 72094 144 72238VN001-086 214814 Vietnam Binh Phuoc VN 500 M 59 13.4 38 23864 0 23864VN001-087 214818 Vietnam Binh Phuoc VN 500 M 18 14.2 43 205230 0 205230VN001-088 214822 Vietnam Binh Phuoc VN 500 M 18 17.5 46 173328 0 173328VN001-089 214828 Vietnam Binh Phuoc VN 500 F 19 12.9 39 39187 0 39187VN001-091 218262 Vietnam Binh Phuoc VN 500 F 39 14.6 42 105504 0 105504VN001-092 218266 Vietnam Binh Phuoc VN 500 F 28 12.6 35 87920 0 87920VN001-093 218270 Vietnam Binh Phuoc VN 500 M 23 12.5 35 26376 0 26376VN001-094 218274 Vietnam Binh Phuoc VN 500 M 56 14.2 40 115552 0 115552VN001-095 218278 Vietnam Binh Phuoc VN 500 M 37 15.6 40 15072 32 15104VN001-096 218282 Vietnam Binh Phuoc VN 500 F 52 11.8 30 11304 0 11304VN001-097 218285 Vietnam Binh Phuoc VN 500 F 20 14.1 40 50240 0 50240VN001-098 218290 Vietnam Binh Phuoc VN 500 M 30 17.2 47 29516 0 29516VN001-099 218294 Vietnam Binh Phuoc VN 500 M 25 12.1 37 23236 0 23236VN001-100 218298 Vietnam Binh Phuoc VN 500 M 26 15.7 42 116054 0 116054VN001-101 227153 Vietnam Binh Phuoc VN 500 F 19 14.2 40 80384 0 80384VN001-102 227154 Vietnam Binh Phuoc VN 500 M 39 16.2 43 43206 0 43206VN001-103 227155 Vietnam Binh Phuoc VN 500 M 21 12 35 158256 0 158256VN001-104 218314 Vietnam Binh Phuoc VN 500 M 22 14.9 43 27004 0 27004VN001-105 218318 Vietnam Binh Phuoc VN 500 M 19 19.3 53 113166 0 113166VN001-106 218322 Vietnam Binh Phuoc VN 500 M 33 17 48 18086 0 18086VN001-107 218326 Vietnam Binh Phuoc VN 500 M 11 12.7 40 50240 0 50240VN001-108 218330 Vietnam Binh Phuoc VN 500 M 15 13.1 44 22106 0 22106VN001-109 218334 Vietnam Binh Phuoc VN 500 M 19 14.3 44 71843 0 71843VN001-110 218338 Vietnam Binh Phuoc VN 500 M 32 15.6 40 80384 0 80384VN001-111 218342 Vietnam Binh Phuoc VN 500 F 38 15.6 39 48984 0 48984VN001-112 218346 Vietnam Binh Phuoc VN 500 M 12 13.4 41 154488 0 154488VN001-113 218350 Vietnam Binh Phuoc VN 500 M 11 11.8 35 101108 0 101108VN001-114 218354 Vietnam Binh Phuoc VN 500 F 43 13.4 35 13188 0 13188

Page 26 of 135


Field site

color



Hb (g/dL) Hct (%)


gam. count


VN001-115 218627 Vietnam Binh Phuoc VN 500 M 27 13 35 158256 0 158256VN001-116 218631 Vietnam Binh Phuoc VN 500 F 44 14.3 39 9797 0 9797VN001-117 218635 Vietnam Binh Phuoc VN 500 F 18 15.3 41 41197 0 41197VN001-118 218639 Vietnam Binh Phuoc VN 500 M 46 13.5 38 14318 0 14318VN001-119 218643 Vietnam Binh Phuoc VN 500 F 23 14 38 38182 0 38182VN001-120 218647 Vietnam Binh Phuoc VN 500 F 24 14.3 42 116054 0 116054

Page 27 of 135


Field site

color

BD001-001 219888 Bangladesh Ramu BDBD001-002 219908 Bangladesh Ramu BDBD001-003 219688 Bangladesh Ramu BDBD001-004 219590 Bangladesh Ramu BDBD001-005 219618 Bangladesh Ramu BDBD001-006 219616 Bangladesh Ramu BDBD001-007 189420 Bangladesh Ramu BDBD001-008 189436 Bangladesh Ramu BDBD001-009 189449 Bangladesh Ramu BDBD001-010 189463 Bangladesh Ramu BDBD001-012 189491 Bangladesh Ramu BDBD001-014 219784 Bangladesh Ramu BDBD001-015 219800 Bangladesh Ramu BDBD001-016 189526 Bangladesh Ramu BDBD001-017 189534 Bangladesh Ramu BDBD001-018 189577 Bangladesh Ramu BDBD001-019 219820 Bangladesh Ramu BDBD001-020 219948 Bangladesh Ramu BDBD001-021 219971 Bangladesh Ramu BDBD001-022 189595 Bangladesh Ramu BDBD001-023 231053 Bangladesh Ramu BDBD001-024 230956 Bangladesh Ramu BDBD001-025 231059 Bangladesh Ramu BDBD001-026 231062 Bangladesh Ramu BDBD001-027 230975 Bangladesh Ramu BDBD001-028 230993 Bangladesh Ramu BDBD001-029 231004 Bangladesh Ramu BDBD001-030 231011 Bangladesh Ramu BDBD001-032 231035 Bangladesh Ramu BDBD001-033 231074 Bangladesh Ramu BDBD001-034 231080 Bangladesh Ramu BDBD001-035 231101 Bangladesh Ramu BDBD001-036 231099 Bangladesh Ramu BDBD001-037 231116 Bangladesh Ramu BDBD001-038 231134 Bangladesh Ramu BDBD001-039 231141 Bangladesh Ramu BDBD001-040 219844 Bangladesh Ramu BD

Table S1. Parasitological and clinical data for the 1,043 Pof headers are in "description" sheet. Data not available

ratio of gam:total parasite

log2 ratio of gam:total parasite

Total parasite in sample (X

1000)

Sampling Time (24-hr)

Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 5426 14.67 36.8 AS2 AM+LUM0.0000000 NA 11555 13.08 36 AS4 AM+LUM0.0000000 NA 17710 13.72 36.9 AS2 AM+LUM0.0000000 NA 112098 13.80 37.3 AS4 AM+LUM0.0000000 NA 8478 13.33 35.6 AS4 AM+LUM0.0000000 NA 5024 17.23 35.3 AS4 AM+LUM0.0000000 NA 21553 13.47 37 AS2 AM+LUM0.0000000 NA 31651 13.50 38 AS4 AM+LUM0.0000000 NA 25748 13.13 35.6 AS2 AM+LUM0.0000000 NA 28260 13.50 36.5 AS4 AM+LUM0.0000000 NA 7536 12.50 34.8 AS2 AM+LUM0.0000000 NA 20096 19.47 36.2 AS2 AM+LUM0.0000000 NA 16705 15.22 38 AS4 AM+LUM0.0000000 NA 8101 13.50 35.6 AS2 AM+LUM0.0000000 NA 10802 13.17 38.6 AS2 AM+LUM0.0000000 NA 24304 14.08 37.4 AS2 AM+LUM0.0000000 NA 87418 16.75 38.1 AS4 AM+LUM0.0000000 NA 8139 13.70 37.3 AS4 AM+LUM0.0000000 NA 5150 16.13 34.8 AS2 AM+LUM0.0000000 NA 7913 14.97 36.9 AS2 AM+LUM0.0000000 NA 13565 18.33 34.3 AS4 AM+LUM0.0000000 NA 9646 13.53 38.1 AS2 AM+LUM0.0000000 NA 64810 13.58 37.7 AS4 AM+LUM0.0000000 NA 13188 13.42 35.4 AS4 AM+LUM0.0000000 NA 9797 14.72 36.8 AS4 AM+LUM0.0000000 NA 9797 10.33 35.8 AS2 AM+LUM0.0000000 NA 10362 13.75 34.7 AS2 AM+LUM0.0000000 NA 7536 16.97 35.1 AS2 AM+LUM0.0000000 NA 27632 13.37 35.1 AS2 AM+LUM0.0000000 NA 5024 12.63 34.1 AS2 AM+LUM0.0000000 NA 8855 15.88 37 AS4 AM+LUM0.0000000 NA 11304 12.80 34.2 AS4 AM+LUM0.0000000 NA 13502 15.13 38.3 AS4 AM+LUM0.0000000 NA 27130 12.55 37.7 AS4 AM+LUM0.0000000 NA 14695 12.63 36.2 AS2 AM+LUM0.0000000 NA 24869 14.80 37.3 AS4 AM+LUM0.0000000 NA 83712 12.22 36.9 AS4 AM+LUM

Page 28 of 135


Field site

color

BD001-041 219855 Bangladesh Ramu BDBD001-042 219866 Bangladesh Ramu BDBD001-043 231148 Bangladesh Ramu BDBD001-044 230854 Bangladesh Ramu BDBD001-045 230866 Bangladesh Ramu BDBD001-046 230757 Bangladesh Ramu BDBD001-047 230771 Bangladesh Ramu BDBD001-048 230779 Bangladesh Ramu BDBD001-049 230793 Bangladesh Ramu BDBD001-050 230803 Bangladesh Ramu BDBD001-051 230816 Bangladesh Ramu BDBD001-052 230828 Bangladesh Ramu BDBD001-053 231162 Bangladesh Ramu BDBD001-054 231175 Bangladesh Ramu BDBD001-055 230877 Bangladesh Ramu BDBD001-056 230889 Bangladesh Ramu BDCD001-001 211757 DRCongo Kinshasa CDCD001-002 211756 DRCongo Kinshasa CDCD001-003 211782 DRCongo Kinshasa CDCD001-004 211784 DRCongo Kinshasa CDCD001-005 211786 DRCongo Kinshasa CDCD001-006 211802 DRCongo Kinshasa CDCD001-007 211818 DRCongo Kinshasa CDCD001-008 NO BC DRCongo Kinshasa CDCD001-009 211833 DRCongo Kinshasa CDCD001-010 211449 DRCongo Kinshasa CDCD001-011 211469 DRCongo Kinshasa CDCD001-012 211468 DRCongo Kinshasa CDCD001-013 211483 DRCongo Kinshasa CDCD001-014 211499 DRCongo Kinshasa CDCD001-015 211503 DRCongo Kinshasa CDCD001-016 211532 DRCongo Kinshasa CDCD001-017 211536 DRCongo Kinshasa CDCD001-018 211539 DRCongo Kinshasa CDCD001-019 211257 DRCongo Kinshasa CDCD001-021 231856 DRCongo Kinshasa CDCD001-023 231888 DRCongo Kinshasa CDCD001-024 231887 DRCongo Kinshasa CDCD001-025 211671 DRCongo Kinshasa CDCD001-026 211673 DRCongo Kinshasa CD




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 38622 13.47 35.5 AS4 AM+LUM0.0000000 NA 7536 16.13 36.9 AS4 AM+LUM0.0000000 NA 12434 11.22 36.6 AS4 AM+LUM0.0000000 NA 8290 15.38 36.3 AS2 NA0.0000000 NA 3956 12.05 35.4 AS2 AM+LUM0.0000000 NA 13502 11.55 35.1 AS2 NA0.0000000 NA 18086 10.05 35.8 AS4 AM+LUM0.0000000 NA 13188 13.93 34.7 AS2 AM+LUM0.0000000 NA 16265 13.55 36.9 AS2 AM+LUM0.0000000 NA 6217 10.88 36.2 AS4 AM+LUM0.0000000 NA 3014 15.38 35 AS4 AM+LUM0.0000000 NA 7348 14.33 37.8 AS2 AM+LUM0.0000000 NA 24869 13.97 39.9 AS2 AM+LUM0.0000000 NA 5778 14.30 36.7 AS4 AM+LUM0.0000000 NA 25434 13.97 38.9 AS2 AM+LUM0.0000000 NA 23738 14.80 34.2 AS4 AM+LUM0.0000000 NA 32970 12.03 37.1 AS4 AM+LUM0.0000000 NA 80070 13.60 37.7 AL AM+LUM0.0000000 NA 6217 12.25 36.2 AS4 AM+LUM0.0015948 -9 12039 13.67 36.7 AS4 AM+LUM0.0000000 NA 4898 14.65 36.1 AS4 AM+LUM0.0007072 -10 6787 13.17 36.3 AL AM+LUM0.0000000 NA 33573 10.57 36.8 AS4 AM+LUM0.0000000 NA 64885 11.92 38.1 AS4 AM+LUM0.0000000 NA 27318 14.93 37.4 AS4 AM+LUM0.0000000 NA 50642 12.08 36.7 AL AM+LUM0.0000000 NA 32782 11.75 36.5 AL AM+LUM0.0000000 NA 181599 12.73 37.7 AL AM+LUM0.0000000 NA 18689 15.72 36.6 AS4 AM+LUM0.0000000 NA 12434 11.58 38 AL AM+LUM0.0000000 NA 102339 13.27 40 AS4 AM+LUM0.0016956 -9 5662 12.07 36.7 AL AM+LUM0.0000000 NA 12246 13.05 37.7 AL AM+LUM0.0002745 -12 17488 13.85 36.1 AL AM+LUM0.0000000 NA 30370 12.08 37.7 AL AM+LUM0.0027617 -9 3476 13.45 37.3 AL AM+LUM0.0001220 -13 39343 12.92 37.5 AL AM+LUM0.0007020 -10 20512 13.23 38.1 AS4 AM+LUM0.0000000 NA 18840 11.88 36.7 AL AM+LUM0.0000000 NA 8139 13.05 38.6 AS4 AM+LUM

Page 29 of 135


Field site

color

CD001-027 211711 DRCongo Kinshasa CDCD001-028 211712 DRCongo Kinshasa CDCD001-029 211713 DRCongo Kinshasa CDCD001-030 NO BC DRCongo Kinshasa CDCD001-031 NO BC DRCongo Kinshasa CDCD001-032 NO BC DRCongo Kinshasa CDCD001-033 NO BC DRCongo Kinshasa CDCD001-034 NO BC DRCongo Kinshasa CDCD001-035 NO BC DRCongo Kinshasa CDCD001-036 NO BC DRCongo Kinshasa CDCD001-037 228679 DRCongo Kinshasa CDCD001-038 228680 DRCongo Kinshasa CDCD001-039 228741 DRCongo Kinshasa CDCD001-040 228578 DRCongo Kinshasa CDCD001-041 228580 DRCongo Kinshasa CDCD001-042 228608 DRCongo Kinshasa CDCD001-044 228657 DRCongo Kinshasa CDCD001-045 228658 DRCongo Kinshasa CDCD001-046 228659 DRCongo Kinshasa CDCD001-047 228905 DRCongo Kinshasa CDCD001-049 228560 DRCongo Kinshasa CDCD001-050 228561 DRCongo Kinshasa CDCD001-051 228562 DRCongo Kinshasa CDCD001-052 228907 DRCongo Kinshasa CDCD001-053 228938 DRCongo Kinshasa CDCD001-054 228964 DRCongo Kinshasa CDCD001-055 228963 DRCongo Kinshasa CDCD001-056 253768 DRCongo Kinshasa CDCD001-057 253769 DRCongo Kinshasa CDCD001-058 253497 DRCongo Kinshasa CDCD001-059 253810 DRCongo Kinshasa CDCD001-061 253481 DRCongo Kinshasa CDCD001-062 253476 DRCongo Kinshasa CDCD001-063 253448 DRCongo Kinshasa CDCD001-064 253691 DRCongo Kinshasa CDCD001-065 253687 DRCongo Kinshasa CDCD001-066 253685 DRCongo Kinshasa CDCD001-068 253659 DRCongo Kinshasa CDCD001-069 253647 DRCongo Kinshasa CDCD001-070 253641 DRCongo Kinshasa CD




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 15826 10.83 37.1 AS4 AM+LUM0.0005134 -11 9349 12.40 37.1 AL AM+LUM0.0000000 NA 65337 13.47 37.3 AL AM+LUM0.0021186 -9 6797 #VALUE! 36.2 AS4 AM+LUM0.0000000 NA 3617 13.60 37.6 AS4 AM+LUM0.0000000 NA 4898 14.50 37.2 AL AM+LUM0.0000000 NA 32329 15.13 36.8 AS4 AM+LUM0.0000000 NA 17408 11.55 36.7 AS4 AM+LUM0.0102071 -7 7994 11.87 36.2 AL AM+LUM0.0054020 -8 48871 14.10 38.6 AL AM+LUM0.0090848 -7 10039 13.47 37 AL AM+LUM0.0000000 NA 12660 14.93 37.7 AS4 AM+LUM0.0000000 NA 12849 12.20 36.8 AS4 AM+LUM0.0000000 NA 16278 12.07 36.2 AS4 AM+LUM0.0009358 -10 5129 12.53 36.4 AS4 AM+LUM0.0000000 NA 7649 12.00 39.1 AL AM+LUM0.0000000 NA 6782 10.62 36 AS4 AM+LUM0.0003061 -12 31359 12.17 36.2 AS4 AM+LUM0.0000000 NA 25472 13.42 36.5 AL AM+LUM0.0000000 NA 34163 10.93 37.1 AS4 AM+LUM0.0005894 -11 8144 12.62 38 AS4 AM+LUM0.0006430 -11 7465 13.22 38.3 AL AM+LUM0.0000000 NA 8139 14.37 37.3 AS4 AM+LUM0.0000000 NA 4974 12.93 37.6 AL AM+LUM0.0003930 -11 12213 12.12 37.5 AL AM+LUM0.0000000 NA 47251 11.25 36.8 AS4 AM+LUM0.0007488 -10 25642 12.87 38.1 AL AM+LUM0.0000000 NA 18463 11.42 36.7 AS4 AM+LUM0.0000000 NA 6406 13.63 37.4 AL AM+LUM0.0000986 -13 48687 11.42 37.8 AL AM+LUM0.0004716 -11 30535 11.58 36.6 AS4 AM+LUM0.0000000 NA 38547 11.88 36.1 AS4 AM+LUM0.0000000 NA 23738 12.67 36.3 AL AM+LUM0.0002144 -12 67160 12.42 36.7 AL AM+LUM0.0000000 NA 9495 12.22 36 AS4 AM+LUM0.0000000 NA 85722 12.33 36.2 AS4 AM+LUM0.0000000 NA 14017 12.83 38 AS4 AM+LUM0.0035261 -8 14974 13.33 36.5 AL AM+LUM0.0000000 NA 59949 12.50 36.3 AS4 AM+LUM0.0000000 NA 10852 12.77 37.5 AS4 AM+LUM

Page 30 of 135


Field site

color

CD001-071 253618 DRCongo Kinshasa CDCD001-072 253621 DRCongo Kinshasa CDCD001-073 253837 DRCongo Kinshasa CDCD001-074 253840 DRCongo Kinshasa CDCD001-075 253865 DRCongo Kinshasa CDCD001-076 253864 DRCongo Kinshasa CDCD001-077 253863 DRCongo Kinshasa CDCD001-078 253884 DRCongo Kinshasa CDCD001-079 253517 DRCongo Kinshasa CDCD001-080 253518 DRCongo Kinshasa CDCD001-081 253910 DRCongo Kinshasa CDCD001-082 253539 DRCongo Kinshasa CDCD001-083 253543 DRCongo Kinshasa CDCD001-084 253546 DRCongo Kinshasa CDCD001-085 253569 DRCongo Kinshasa CDCD001-086 253572 DRCongo Kinshasa CDCD001-087 253609 DRCongo Kinshasa CDCD001-088 253612 DRCongo Kinshasa CDCD001-089 254935 DRCongo Kinshasa CDCD001-090 254931 DRCongo Kinshasa CDCD001-091 254927 DRCongo Kinshasa CDCD001-092 254968 DRCongo Kinshasa CDCD001-093 254971 DRCongo Kinshasa CDCD001-094 254989 DRCongo Kinshasa CDCD001-095 254991 DRCongo Kinshasa CDCD001-096 255010 DRCongo Kinshasa CDCD001-097 255006 DRCongo Kinshasa CDCD001-098 255046 DRCongo Kinshasa CDCD001-099 255040 DRCongo Kinshasa CDCD001-100 255037 DRCongo Kinshasa CDCD001-101 255064 DRCongo Kinshasa CDCD001-102 255076 DRCongo Kinshasa CDCD001-103 255097 DRCongo Kinshasa CDCD001-104 255101 DRCongo Kinshasa CDCD001-105 255100 DRCongo Kinshasa CDCD001-106 254520 DRCongo Kinshasa CDCD001-107 254538 DRCongo Kinshasa CDCD001-108 254542 DRCongo Kinshasa CDCD001-109 254557 DRCongo Kinshasa CDCD001-110 254584 DRCongo Kinshasa CD




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0013275 -10 21695 12.50 39.3 AS4 AM+LUM0.0000000 NA 20498 13.42 37.4 AL AM+LUM0.0000000 NA 30596 11.00 37.6 AL AM+LUM

NA NA NA 11.23 37.4 AL AM+LUM0.0000000 NA 9232 11.90 38 AS4 AM+LUM0.0000000 NA 3730 12.43 36.7 AL AM+LUM0.0000000 NA 55390 12.75 37.4 AL AM+LUM0.0003537 -11 13570 11.65 36.5 AL AM+LUM0.0003184 -12 15077 11.55 36.3 AS4 AM+LUM0.0000000 NA 18689 11.27 37.6 AL AM+LUM0.0000000 NA 6330 12.75 36.3 AL AM+LUM0.0000000 NA 51396 11.50 36.3 AS4 AM+LUM0.0021729 -9 26509 12.25 36.9 AS4 AM+LUM0.0090171 -7 4259 12.83 36.5 AS4 AM+LUM0.0000000 NA 13188 11.17 36.1 AL AM+LUM0.0000000 NA 93823 11.92 37.6 AS4 AM+LUM0.0004421 -11 10857 11.92 36.9 AS4 AM+LUM0.0000000 NA 3956 12.95 36.5 AS4 AM+LUM0.0000000 NA 108142 11.83 36.4 AS4 AM+LUM0.0001174 -13 40888 12.75 36.1 AL AM+LUM0.0000000 NA 48230 13.32 36.3 AL AM+LUM0.0056548 -7 4244 11.38 38.1 AS4 AM+LUM0.0017127 -9 22420 13.30 36.9 AL AM+LUM0.0000000 NA 24341 13.10 36 AS4 AM+LUM0.0003184 -12 15077 13.18 36.5 AL AM+LUM0.0000000 NA 18086 12.60 36.9 AL AM+LUM0.0000000 NA 13113 13.28 37.9 AL AM+LUM0.0024916 -9 11559 11.13 36 AL AM+LUM0.0000000 NA 21101 11.50 36 AS4 AM+LUM0.0000000 NA 92844 12.00 36.5 AL AM+LUM0.0000000 NA 64433 12.30 36.8 AS4 AM+LUM0.0000000 NA 23701 12.13 37.3 AS4 AM+LUM0.0000000 NA 7122 11.83 38.7 AL AM+LUM0.0000000 NA 35042 13.08 36.2 AL AM+LUM0.0003537 -11 13570 13.05 36.2 AS4 AM+LUM0.0000000 NA 11191 11.37 37 AL AM+LUM0.0000000 NA 37379 12.22 37 AL AM+LUM0.0000000 NA 32970 12.72 36.4 AS4 AM+LUM0.0000000 NA 15826 11.67 37.9 AS4 AM+LUM0.0006512 -11 14742 12.17 36.3 AS4 AM+LUM

Page 31 of 135


Field site

color

CD001-111 254585 DRCongo Kinshasa CDCD001-112 254588 DRCongo Kinshasa CDCD001-113 254612 DRCongo Kinshasa CDCD001-114 254613 DRCongo Kinshasa CDCD001-115 254614 DRCongo Kinshasa CDCD001-116 254494 DRCongo Kinshasa CDCD001-117 254487 DRCongo Kinshasa CDCD001-118 254483 DRCongo Kinshasa CDCD001-119 254451 DRCongo Kinshasa CDCD001-120 254449 DRCongo Kinshasa CDKH001-001 188118 Cambodia Pursat KH1KH001-004 188209 Cambodia Pursat KH1KH001-005 188208 Cambodia Pursat KH1KH001-006 188127 Cambodia Pursat KH1KH001-007 188129 Cambodia Pursat KH1KH001-011 188204 Cambodia Pursat KH1KH001-012 188198 Cambodia Pursat KH1KH001-013 188144 Cambodia Pursat KH1KH001-015 188181 Cambodia Pursat KH1KH001-016 188176 Cambodia Pursat KH1KH001-017 188174 Cambodia Pursat KH1KH001-018 188173 Cambodia Pursat KH1KH001-020 194265 Cambodia Pursat KH1KH001-021 194272 Cambodia Pursat KH1KH001-022 194286 Cambodia Pursat KH1KH001-023 194291 Cambodia Pursat KH1KH001-024 194298 Cambodia Pursat KH1KH001-025 194306 Cambodia Pursat KH1KH001-026 194314 Cambodia Pursat KH1KH001-028 194335 Cambodia Pursat KH1KH001-029 194349 Cambodia Pursat KH1KH001-030 199332 Cambodia Pursat KH1KH001-031 199342 Cambodia Pursat KH1KH001-032 199343 Cambodia Pursat KH1KH001-034 193757 Cambodia Pursat KH1KH001-036 193959 Cambodia Pursat KH1KH001-038 193778 Cambodia Pursat KH1KH001-039 193972 Cambodia Pursat KH1KH001-040 193974 Cambodia Pursat KH1KH001-041 193987 Cambodia Pursat KH1




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 10852 12.97 36.1 AS4 AM+LUM0.0000000 NA 21704 13.25 37.7 AL AM+LUM0.0000000 NA 18086 11.67 37.7 AL AM+LUM0.0000000 NA 11869 11.70 36.6 AS4 AM+LUM0.0002426 -12 19787 12.67 37.3 AS4 AM+LUM0.0000000 NA 30860 11.77 37.8 AL AM+LUM0.0000000 NA 13226 12.67 36.5 AL AM+LUM0.0000000 NA 68954 13.00 36 AS4 AM+LUM0.0000000 NA 79128 11.27 38.2 AL AM+LUM0.0000000 NA 17936 11.48 38.2 AL AM+LUM0.0000000 NA 22608 14.62 39 AS4 DHA+PPQ0.0000000 NA 23487 18.03 37.9 AS4 DHA+PPQ0.0000000 NA 63679 18.82 39.5 AS4 DHA+PPQ0.0000000 NA 54259 16.70 38 AS4 DHA+PPQ0.0000000 NA 50114 11.87 39.3 AS4 DHA+PPQ0.0000000 NA 4898 17.78 40 AS4 DHA+PPQ0.0000000 NA 120011 10.02 39 AS4 DHA+PPQ0.0000000 NA 17270 9.98 38 AS4 DHA+PPQ0.0000000 NA 21603 17.00 40 AS4 DHA+PPQ0.0000000 NA 53694 16.23 39 AS4 DHA+PPQ0.0000000 NA 27632 17.35 39.5 AS4 DHA+PPQ0.2727273 -2 22106 14.75 39.8 AS4 DHA+PPQ0.0000000 NA 18903 15.97 39 AS4 DHA+PPQ0.0000000 NA 54887 11.45 39.5 AS4 DHA+PPQ0.0000000 NA 54887 10.45 37.8 AS4 DHA+PPQ0.0000000 NA 87543 10.87 40 AS4 DHA+PPQ0.0000000 NA 16956 15.98 38.5 AS4 DHA+PPQ0.0000000 NA 29516 16.30 38.5 AS4 DHA+PPQ0.0000000 NA 57650 16.55 38 AS4 DHA+PPQ0.0002341 -12 34171 16.20 39 AS4 DHA+PPQ0.0000000 NA 69080 16.67 40 AS4 DHA+PPQ0.0000000 NA 110214 10.63 41 AS4 DHA+PPQ0.0000000 NA 28260 17.05 38.5 AS4 DHA+PPQ0.0000000 NA 39564 16.80 38.5 AS4 DHA+PPQ0.0714286 -4 29893 16.07 38.7 AS4 DHA+PPQ0.0002868 -12 27891 9.80 40 AS4 DHA+PPQ0.0001484 -13 32334 16.42 38.3 AS4 DHA+PPQ0.0000000 NA 62800 10.25 38 AS4 DHA+PPQ0.0001956 -12 40891 10.90 38 AS4 DHA+PPQ0.0000000 NA 21101 10.97 38 AS4 DHA+PPQ

Page 32 of 135


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color

KH001-043 199352 Cambodia Pursat KH1KH001-044 194008 Cambodia Pursat KH1KH001-046 199364 Cambodia Pursat KH1KH001-047 199363 Cambodia Pursat KH1KH001-048 194024 Cambodia Pursat KH1KH001-049 194037 Cambodia Pursat KH1KH001-051 199356 Cambodia Pursat KH1KH001-052 193787 Cambodia Pursat KH1KH001-054 193799 Cambodia Pursat KH1KH001-055 194051 Cambodia Pursat KH1KH001-056 193812 Cambodia Pursat KH1KH001-057 193821 Cambodia Pursat KH1KH001-058 193822 Cambodia Pursat KH1KH001-059 193849 Cambodia Pursat KH1KH001-060 188056 Cambodia Pursat KH1KH001-061 193838 Cambodia Pursat KH1KH001-062 188068 Cambodia Pursat KH1KH001-063 193825 Cambodia Pursat KH1KH001-064 188073 Cambodia Pursat KH1KH001-065 188075 Cambodia Pursat KH1KH001-066 188082 Cambodia Pursat KH1KH001-067 188087 Cambodia Pursat KH1KH001-068 188096 Cambodia Pursat KH1KH001-069 188098 Cambodia Pursat KH1KH001-070 188101 Cambodia Pursat KH1KH001-071 188102 Cambodia Pursat KH1KH001-072 188104 Cambodia Pursat KH1KH001-073 208405 Cambodia Pursat KH1KH001-074 208412 Cambodia Pursat KH1KH001-075 208422 Cambodia Pursat KH1KH001-076 208424 Cambodia Pursat KH1KH001-077 208433 Cambodia Pursat KH1KH001-078 208435 Cambodia Pursat KH1KH001-079 202262 Cambodia Pursat KH1KH001-080 202274 Cambodia Pursat KH1KH001-081 202283 Cambodia Pursat KH1KH001-082 202288 Cambodia Pursat KH1KH001-083 202293 Cambodia Pursat KH1KH001-084 202303 Cambodia Pursat KH1KH001-086 202310 Cambodia Pursat KH1




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 37680 16.60 40 AS4 DHA+PPQ0.0000000 NA 9734 12.63 39 AS4 DHA+PPQ0.0000000 NA 96712 15.07 40.5 AS4 DHA+PPQ0.0000000 NA 69080 16.03 39.5 AS4 DHA+PPQ0.0002071 -12 38630 14.98 39 AS4 DHA+PPQ0.0000000 NA 11304 16.43 39 AS4 DHA+PPQ0.0000000 NA 66128 17.08 39 AS4 DHA+PPQ0.0000000 NA 34666 11.37 38 AS4 DHA+PPQ0.1111111 -3 22043 10.98 38 AS4 DHA+PPQ0.0000000 NA 54008 10.15 38.5 AS4 DHA+PPQ0.0833333 -4 30898 11.32 38 AS4 DHA+PPQ0.0000000 NA 20724 9.82 38 AS4 DHA+PPQ0.0173242 -6 8589 16.48 38 AS4 DHA+PPQ0.0000000 NA 21553 11.67 38.5 AS4 DHA+PPQ0.0000000 NA 16165 11.35 39 AS4 DHA+PPQ0.0000000 NA 12359 15.97 38.5 AS4 DHA+PPQ0.0000000 NA 20310 11.57 39 AS4 DHA+PPQ0.0001769 -12 27134 16.07 40 AS4 DHA+PPQ0.0000000 NA 40506 15.47 40 AS4 DHA+PPQ0.0000000 NA 6029 15.95 38.5 AS4 DHA+PPQ0.0000000 NA 82645 16.10 39 AS4 DHA+PPQ0.0000000 NA 4522 18.13 38 AS4 DHA+PPQ0.0000000 NA 25120 11.30 39 AS4 DHA+PPQ0.0000000 NA 91060 11.02 39 AS4 DHA+PPQ0.0000000 NA 22307 16.45 39.5 AS4 DHA+PPQ0.0000000 NA 7913 11.98 38.5 AS4 DHA+PPQ0.0013252 -10 6037 16.47 40 AS4 DHA+PPQ0.0000000 NA 24115 16.72 38 AS4 DHA+PPQ0.0000000 NA 14507 11.98 38.5 AS4 DHA+PPQ0.0000000 NA 19594 5.33 38.5 AS4 DHA+PPQ0.0000000 NA 26376 16.15 38.5 AS4 DHA+PPQ0.0000000 NA 22608 11.25 37.5 AS4 DHA+PPQ0.0000000 NA 30207 11.97 39 AS4 DHA+PPQ0.0000000 NA 28637 10.72 39 AS4 DHA+PPQ0.0000000 NA 65312 12.13 39 AS4 DHA+PPQ0.0000000 NA 37366 10.40 38 AS4 DHA+PPQ0.0000000 NA 56520 11.53 40 AS4 DHA+PPQ0.0000000 NA 47728 15.97 39 AS4 NA0.0000000 NA 75360 11.05 38 AS4 DHA+PPQ0.0000000 NA 142430 16.65 38.5 AS4 DHA+PPQ

Page 33 of 135


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color

KH001-087 202323 Cambodia Pursat KH1KH001-088 202330 Cambodia Pursat KH1KH001-089 202328 Cambodia Pursat KH1KH001-090 202340 Cambodia Pursat KH1KH001-091 202353 Cambodia Pursat KH1KH001-092 194459 Cambodia Pursat KH1KH001-093 194468 Cambodia Pursat KH1KH001-094 194474 Cambodia Pursat KH1KH001-095 194491 Cambodia Pursat KH1KH001-096 194503 Cambodia Pursat KH1KH001-097 194553 Cambodia Pursat KH1KH001-098 194550 Cambodia Pursat KH1KH001-099 194524 Cambodia Pursat KH1KH001-100 202110 Cambodia Pursat KH1KH001-101 202097 Cambodia Pursat KH1KH001-102 202073 Cambodia Pursat KH1KH001-103 202074 Cambodia Pursat KH1KH001-104 216376 Cambodia Pursat KH1KH001-105 216377 Cambodia Pursat KH1KH001-106 216385 Cambodia Pursat KH1KH001-107 216391 Cambodia Pursat KH1KH001-108 216395 Cambodia Pursat KH1KH001-109 216402 Cambodia Pursat KH1KH001-110 216407 Cambodia Pursat KH1KH001-111 217165 Cambodia Pursat KH1KH001-112 217466 Cambodia Pursat KH1KH001-113 217468 Cambodia Pursat KH1KH001-114 215759 Cambodia Pursat KH1KH001-116 236285 Cambodia Pursat KH1KH001-117 236300 Cambodia Pursat KH1KH001-118 236292 Cambodia Pursat KH1KH001-119 236308 Cambodia Pursat KH1KH001-120 236363 Cambodia Pursat KH1KH002-001 188418 Cambodia Preah Vihear KH2KH002-002 188426 Cambodia Preah Vihear KH2KH002-003 188428 Cambodia Preah Vihear KH2KH002-005 188439 Cambodia Preah Vihear KH2KH002-006 188440 Cambodia Preah Vihear KH2KH002-007 188442 Cambodia Preah Vihear KH2KH002-008 188452 Cambodia Preah Vihear KH2




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 18086 12.12 39 AS4 DHA+PPQ0.0000000 NA 81138 15.93 39 AS4 DHA+PPQ0.0000000 NA 33912 16.53 38.5 AS4 DHA+PPQ0.0017662 -9 9059 12.35 39 AS4 DHA+PPQ0.0000000 NA 16202 12.80 39 AS4 DHA+PPQ0.0000000 NA 107765 18.50 38.8 AS4 DHA+PPQ0.0006918 -10 46253 10.30 39 AS4 DHA+PPQ0.0000000 NA 10990 16.17 38.5 AS4 DHA+PPQ0.0000000 NA 7536 16.12 38.5 AS4 DHA+PPQ0.0000000 NA 11304 11.55 39 AS4 DHA+PPQ0.0006700 -11 11940 15.98 38 AS4 DHA+PPQ0.0000000 NA 29390 15.00 39 AS4 DHA+PPQ0.0025079 -9 28709 11.30 38 AS4 DHA+PPQ0.0000000 NA 24115 15.48 39 AS4 DHA+PPQ0.0000000 NA 39501 16.28 40 AS4 DHA+PPQ0.0000000 NA 123151 16.98 40 AS4 DHA+PPQ0.0045290 -8 17664 12.05 38 AS4 DHA+PPQ0.0000000 NA 12246 16.23 38 AS4 DHA+PPQ0.0033411 -8 19155 16.47 38 AS4 DHA+PPQ0.0000000 NA 82896 11.88 38.8 AS4 DHA+PPQ0.0000000 NA 21779 17.20 38.5 AS4 DHA+PPQ0.0000000 NA 21603 16.18 38.5 AS4 DHA+PPQ0.0007955 -10 20112 11.57 38.8 AS4 DHA+PPQ0.0000000 NA 9546 15.98 38.5 AS4 DHA+PPQ0.0037327 -8 12859 13.50 38.5 AS4 DHA+PPQ0.0021186 -9 22656 15.10 39.5 AS4 DHA+PPQ0.0000000 NA 16705 15.85 38.5 AS4 DHA+PPQ0.0000000 NA 15072 13.63 38 AS4 DHA+PPQ0.0000000 NA 5464 16.82 38 AS4 DHA+PPQ0.0000000 NA 12811 11.05 39 AS4 DHA+PPQ0.0000000 NA 17584 11.35 39.5 AS4 DHA+PPQ0.0000000 NA 14771 15.98 39 AS4 DHA+PPQ0.1666667 -3 29390 11.48 39 AS4 DHA+PPQ0.0000000 NA 32656 11.28 36.5 AS2 DHA+PPQ0.0000000 NA 22608 16.77 38.3 AS2 DHA+PPQ0.0000000 NA 28637 17.43 37.3 AS2 DHA+PPQ0.0000000 NA 16705 17.12 39.2 AS4 DHA+PPQ0.0000000 NA 6971 17.47 39.4 AS4 DHA+PPQ0.0000000 NA 16353 11.28 38.2 AS4 DHA+PPQ0.0000000 NA 23738 16.72 36.4 AS4 DHA+PPQ

Page 34 of 135


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color

KH002-009 188455 Cambodia Preah Vihear KH2KH002-010 188458 Cambodia Preah Vihear KH2KH002-011 188464 Cambodia Preah Vihear KH2KH002-012 188468 Cambodia Preah Vihear KH2KH002-013 188470 Cambodia Preah Vihear KH2KH002-014 188359 Cambodia Preah Vihear KH2KH002-015 188364 Cambodia Preah Vihear KH2KH002-016 188365 Cambodia Preah Vihear KH2KH002-017 188367 Cambodia Preah Vihear KH2KH002-018 188406 Cambodia Preah Vihear KH2KH002-019 188409 Cambodia Preah Vihear KH2KH002-020 188408 Cambodia Preah Vihear KH2KH002-021 188492 Cambodia Preah Vihear KH2KH002-022 188489 Cambodia Preah Vihear KH2KH002-023 198471 Cambodia Preah Vihear KH2KH002-024 198476 Cambodia Preah Vihear KH2KH002-025 198484 Cambodia Preah Vihear KH2KH002-027 198486 Cambodia Preah Vihear KH2KH002-028 198487 Cambodia Preah Vihear KH2KH002-029 198499 Cambodia Preah Vihear KH2KH002-030 198496 Cambodia Preah Vihear KH2KH002-031 198514 Cambodia Preah Vihear KH2KH002-032 198516 Cambodia Preah Vihear KH2KH002-033 198525 Cambodia Preah Vihear KH2KH002-034 198527 Cambodia Preah Vihear KH2KH002-035 198536 Cambodia Preah Vihear KH2KH002-036 198538 Cambodia Preah Vihear KH2KH002-037 198540 Cambodia Preah Vihear KH2KH002-038 198542 Cambodia Preah Vihear KH2KH002-039 198551 Cambodia Preah Vihear KH2KH002-040 198560 Cambodia Preah Vihear KH2KH002-041 198562 Cambodia Preah Vihear KH2KH002-042 198584 Cambodia Preah Vihear KH2KH002-043 198564 Cambodia Preah Vihear KH2KH002-044 207295 Cambodia Preah Vihear KH2KH002-045 198574 Cambodia Preah Vihear KH2KH002-046 207297 Cambodia Preah Vihear KH2KH002-047 207446 Cambodia Preah Vihear KH2KH002-048 198573 Cambodia Preah Vihear KH2KH002-049 207448 Cambodia Preah Vihear KH2




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 37366 18.05 38.9 AS2 DHA+PPQ0.0000000 NA 85408 10.85 39 AS4 DHA+PPQ0.0000000 NA 89113 16.97 37.8 AS4 DHA+PPQ0.0000000 NA 40443 17.37 36.7 AS2 DHA+PPQ0.0000000 NA 85722 17.17 37.5 AS2 DHA+PPQ0.0000000 NA 26376 16.82 38.3 AS4 DHA+PPQ0.0000000 NA 20598 16.15 36.5 AS4 DHA+PPQ0.0000000 NA 51245 16.47 38.8 AS4 DHA+PPQ0.0000000 NA 155618 17.02 38.9 AS2 DHA+PPQ0.0000000 NA 31086 11.77 38.7 AS2 DHA+PPQ0.0000000 NA 40192 11.60 39.5 AS2 DHA+PPQ0.0000000 NA 15826 11.72 37.3 AS2 DHA+PPQ0.0000000 NA 36173 16.50 38.9 AS4 DHA+PPQ0.0000000 NA 26125 16.88 38.1 AS2 DHA+PPQ0.0000000 NA 28323 17.12 38.1 AS4 DHA+PPQ0.0000000 NA 21478 11.43 37.6 AS4 DHA+PPQ0.0000000 NA 46974 17.23 37.7 AS4 DHA+PPQ0.0000000 NA 27632 17.02 37.1 AS2 DHA+PPQ0.0000000 NA 33912 17.17 37.3 AS4 DHA+PPQ0.0000000 NA 16165 16.92 36.8 AS4 DHA+PPQ0.0000000 NA 19342 17.48 36.7 AS2 DHA+PPQ0.0000000 NA 31086 11.50 38.5 AS2 DHA+PPQ0.0000000 NA 21352 12.18 37.6 AS2 DHA+PPQ0.0000000 NA 28637 16.75 37.3 AS2 DHA+PPQ0.0000000 NA 51433 17.08 37.3 AS2 DHA+PPQ0.0019560 -9 16360 16.55 36.5 AS4 DHA+PPQ0.0000000 NA 82394 10.92 36.4 AS2 DHA+PPQ0.0000000 NA 15373 11.50 37.9 AS2 DHA+PPQ0.0004452 -11 21563 11.67 37.8 AS4 DHA+PPQ0.0000000 NA 18903 16.88 38.2 AS4 DHA+PPQ0.0088200 -7 17234 11.30 36.1 AS2 DHA+PPQ0.0000000 NA 59786 17.07 36.7 AS4 DHA+PPQ0.0000000 NA 28134 11.78 36.5 AS4 DHA+PPQ0.0000000 NA 22608 16.52 36.4 AS2 DHA+PPQ0.0000000 NA 22608 16.78 37.8 AS4 DHA+PPQ0.0000000 NA 22043 16.92 37.2 AS4 DHA+PPQ0.0000000 NA 19468 17.12 37.5 AS2 DHA+PPQ0.0000000 NA 10990 11.28 39.1 AS4 DHA+PPQ0.0000000 NA 41448 10.97 39.1 AS4 DHA+PPQ0.0000000 NA 31350 11.42 37.8 AS2 DHA+PPQ

Page 35 of 135


Field site

color





1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 42955 11.53 38.8 AS4 DHA+PPQ0.0000000 NA 87041 11.35 39 AS4 DHA+PPQ0.0000000 NA 39501 16.73 36.6 AS2 DHA+PPQ0.0000000 NA 31023 16.95 36.1 AS2 DHA+PPQ0.0000000 NA 52752 17.17 36.4 AS2 DHA+PPQ0.0000000 NA 26250 17.37 36.9 AS4 DHA+PPQ0.0000000 NA 34163 10.97 36.7 AS2 DHA+PPQ0.0000000 NA 46346 17.27 37 AS4 DHA+PPQ0.0000000 NA 11304 17.03 37.8 AS2 DHA+PPQ0.0000000 NA 40820 16.92 36.7 AS2 DHA+PPQ0.0000000 NA 21603 17.17 36.3 AS2 DHA+PPQ0.0000000 NA 42955 11.28 38.2 AS4 DHA+PPQ0.0000000 NA 28260 16.95 38.4 AS2 DHA+PPQ0.0000000 NA 17584 11.55 37.6 AS2 DHA+PPQ0.0000000 NA 42830 17.23 36.7 AS4 DHA+PPQ0.0000000 NA 8792 11.15 36.9 AS2 DHA+PPQ0.0000000 NA 25748 11.38 39.1 AS4 DHA+PPQ0.0000000 NA 40506 17.08 37.5 AS4 DHA+PPQ0.0000000 NA 20912 17.18 36.7 AS4 DHA+PPQ0.0000000 NA 19594 17.25 36.6 AS2 DHA+PPQ0.0000000 NA 19594 17.07 36 AS2 DHA+PPQ0.0000000 NA 35922 17.55 37.9 AS2 DHA+PPQ0.0000000 NA 8541 11.40 39.2 AS4 DHA+PPQ0.0000000 NA 30898 11.25 37.9 AS4 DHA+PPQ0.0000000 NA 12874 11.87 35.4 AS2 DHA+PPQ0.0000000 NA 46221 11.60 36.7 AS2 DHA+PPQ0.0000000 NA 35419 11.73 39 AS4 DHA+PPQ0.0000000 NA 26376 17.13 38.5 AS4 DHA+PPQ0.0000000 NA 44211 11.32 36.2 AS4 DHA+PPQ0.0000000 NA 61921 17.25 38.2 AS2 DHA+PPQ0.0010834 -10 81226 11.27 37 AS2 DHA+PPQ0.0000000 NA 14695 16.30 40 AS2 DHA+PPQ0.0000000 NA 40431 16.67 38.8 AS2 DHA+PPQ0.0000000 NA 19217 17.00 38.2 AS4 DHA+PPQ0.0000000 NA 16165 16.98 38.5 AS2 DHA+PPQ0.0000000 NA 8290 11.20 39.8 AS2 DHA+PPQ0.0000000 NA 31840 17.45 37.9 AS4 DHA+PPQ0.0001341 -13 119336 11.63 39.9 AS4 DHA+PPQ0.0000000 NA 14017 11.10 39.2 AS2 DHA+PPQ0.0000000 NA 11932 16.82 38 AS4 DHA+PPQ

Page 36 of 135


Field site

color

KH002-091 213753 Cambodia Preah Vihear KH2KH002-092 213764 Cambodia Preah Vihear KH2KH002-093 236214 Cambodia Preah Vihear KH2KH002-094 213785 Cambodia Preah Vihear KH2KH002-095 213793 Cambodia Preah Vihear KH2KH002-096 213808 Cambodia Preah Vihear KH2KH002-097 213810 Cambodia Preah Vihear KH2KH002-098 236247 Cambodia Preah Vihear KH2KH002-099 236258 Cambodia Preah Vihear KH2KH002-100 236260 Cambodia Preah Vihear KH2KH002-101 236262 Cambodia Preah Vihear KH2KH002-102 236274 Cambodia Preah Vihear KH2KH002-103 236084 Cambodia Preah Vihear KH2KH002-104 236092 Cambodia Preah Vihear KH2KH002-105 236131 Cambodia Preah Vihear KH2KH002-106 236170 Cambodia Preah Vihear KH2KH002-107 236172 Cambodia Preah Vihear KH2KH002-108 236175 Cambodia Preah Vihear KH2KH002-109 236376 Cambodia Preah Vihear KH2KH002-110 236379 Cambodia Preah Vihear KH2KH002-111 236447 Cambodia Preah Vihear KH2KH002-112 236438 Cambodia Preah Vihear KH2KH002-114 236427 Cambodia Preah Vihear KH2KH002-115 236424 Cambodia Preah Vihear KH2KH002-116 236416 Cambodia Preah Vihear KH2KH002-117 216493 Cambodia Preah Vihear KH2KH002-118 216558 Cambodia Preah Vihear KH2KH002-119 216571 Cambodia Preah Vihear KH2KH002-120 216557 Cambodia Preah Vihear KH2KH003-004 188680 Cambodia Ratanakiri KH3KH003-009 188531 Cambodia Ratanakiri KH3KH003-010 188537 Cambodia Ratanakiri KH3KH003-011 188708 Cambodia Ratanakiri KH3KH003-012 198592 Cambodia Ratanakiri KH3KH003-013 198988 Cambodia Ratanakiri KH3KH003-015 198991 Cambodia Ratanakiri KH3KH003-016 198993 Cambodia Ratanakiri KH3KH003-017 198995 Cambodia Ratanakiri KH3KH003-018 199002 Cambodia Ratanakiri KH3KH003-019 199011 Cambodia Ratanakiri KH3




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 24115 16.98 36.2 AS2 DHA+PPQ0.0000000 NA 23173 17.17 36.6 AS4 DHA+PPQ0.0000000 NA 34603 11.33 38.8 AS4 DHA+PPQ0.0000000 NA 25622 17.03 38.2 AS2 DHA+PPQ0.0000000 NA 16328 17.13 37.1 AS4 DHA+PPQ0.0000000 NA 15826 17.33 37.2 AS2 DHA+PPQ0.0000000 NA 21352 17.53 36.7 AS2 DHA+PPQ0.0000000 NA 67824 17.93 39 AS4 DHA+PPQ0.0000000 NA 39564 11.22 36.8 AS4 DHA+PPQ0.0000000 NA 39338 11.50 38.6 AS4 DHA+PPQ0.0000000 NA 60414 17.87 36.9 AS4 DHA+PPQ0.0000000 NA 58467 11.05 37.6 AS2 DHA+PPQ0.0000000 NA 11304 17.02 38.6 AS4 DHA+PPQ0.0000000 NA 122460 11.35 36.5 AS4 DHA+PPQ0.0000000 NA 43520 11.58 38.9 AS2 DHA+PPQ0.0000000 NA 7159 12.03 37.3 AS2 DHA+PPQ0.0000000 NA 17144 16.98 36.2 AS4 DHA+PPQ0.0000000 NA 98219 17.75 37.2 AS4 DHA+PPQ0.0000000 NA 18463 11.32 37.1 AS2 DHA+PPQ0.0000000 NA 88171 17.27 37.2 AS2 DHA+PPQ0.0000000 NA 27758 11.10 38.4 AS2 DHA+PPQ0.0000000 NA 42390 17.37 37.5 AS4 DHA+PPQ0.0000000 NA 26376 16.97 37.5 AS4 DHA+PPQ0.0000000 NA 90432 17.22 37.5 AS4 DHA+PPQ0.0000000 NA 37680 17.13 38.4 AS4 DHA+PPQ0.0000000 NA 43206 16.98 36.3 AS2 DHA+PPQ0.0000000 NA 24115 11.75 36.5 AS4 DHA+PPQ0.0000000 NA 16579 17.18 37.2 AS2 DHA+PPQ0.0000000 NA 7724 17.53 38.1 AS2 DHA+PPQ0.0000000 NA 22043 18.18 36.5 AS4 DHA+PPQ0.0000000 NA 44148 17.25 36.9 AS4 DHA+PPQ0.0000000 NA 56457 16.58 36.5 AS4 DHA+PPQ0.0000000 NA 10174 17.00 37.1 AS2 DHA+PPQ0.0000000 NA 19342 12.67 39.5 AS4 DHA+PPQ0.0000000 NA 14507 17.33 37.1 AS2 DHA+PPQ0.0000000 NA 35922 12.47 35.4 AS4 DHA+PPQ0.0000000 NA 8290 17.18 36.4 AS4 DHA+PPQ0.0000000 NA 14444 16.93 37.3 AS4 DHA+PPQ0.0000000 NA 19091 16.62 36 AS2 DHA+PPQ0.0000000 NA 74732 16.38 39.5 AS4 DHA+PPQ

Page 37 of 135


Field site

color

KH003-020 199012 Cambodia Ratanakiri KH3KH003-021 199016 Cambodia Ratanakiri KH3KH003-022 198647 Cambodia Ratanakiri KH3KH003-024 198650 Cambodia Ratanakiri KH3KH003-025 198651 Cambodia Ratanakiri KH3KH003-027 199029 Cambodia Ratanakiri KH3KH003-028 199071 Cambodia Ratanakiri KH3KH003-029 202663 Cambodia Ratanakiri KH3KH003-030 202662 Cambodia Ratanakiri KH3KH003-031 202667 Cambodia Ratanakiri KH3KH003-032 202477 Cambodia Ratanakiri KH3KH003-033 202675 Cambodia Ratanakiri KH3KH003-034 188599 Cambodia Ratanakiri KH3KH003-035 202494 Cambodia Ratanakiri KH3KH003-036 202681 Cambodia Ratanakiri KH3KH003-037 202682 Cambodia Ratanakiri KH3KH003-038 202516 Cambodia Ratanakiri KH3KH003-039 202687 Cambodia Ratanakiri KH3KH003-040 202686 Cambodia Ratanakiri KH3KH003-041 202693 Cambodia Ratanakiri KH3KH003-042 202692 Cambodia Ratanakiri KH3KH003-043 202540 Cambodia Ratanakiri KH3KH003-044 202700 Cambodia Ratanakiri KH3KH003-045 207965 Cambodia Ratanakiri KH3KH003-046 207970 Cambodia Ratanakiri KH3KH003-047 207987 Cambodia Ratanakiri KH3KH003-048 207998 Cambodia Ratanakiri KH3KH003-049 207999 Cambodia Ratanakiri KH3KH003-050 208017 Cambodia Ratanakiri KH3KH003-051 208021 Cambodia Ratanakiri KH3KH003-052 208018 Cambodia Ratanakiri KH3KH003-053 208022 Cambodia Ratanakiri KH3KH003-054 207556 Cambodia Ratanakiri KH3KH003-055 207557 Cambodia Ratanakiri KH3KH003-056 207558 Cambodia Ratanakiri KH3KH003-057 207593 Cambodia Ratanakiri KH3KH003-058 207592 Cambodia Ratanakiri KH3KH003-059 207586 Cambodia Ratanakiri KH3KH003-060 207587 Cambodia Ratanakiri KH3KH003-061 207610 Cambodia Ratanakiri KH3




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 58781 17.17 37.3 AS2 DHA+PPQ0.0000000 NA 64433 18.97 38.5 AS2 DHA+PPQ0.0000000 NA 17710 16.32 37.2 AS2 DHA+PPQ0.0000000 NA 16014 16.73 39.1 AS4 DHA+PPQ0.0000000 NA 96712 16.03 38.7 AS2 DHA+PPQ0.0000000 NA 40569 17.00 37.3 AS4 DHA+PPQ0.0000000 NA 25120 13.23 36.4 AS4 DHA+PPQ0.0000000 NA 46535 16.72 36.8 AS2 DHA+PPQ0.0000000 NA 15336 16.98 37.5 AS4 DHA+PPQ0.0000000 NA 43772 16.47 37.7 AS4 DHA+PPQ0.0000000 NA 58781 17.75 38.5 AS4 DHA+PPQ0.0000000 NA 2512 17.28 35.6 AS2 DHA+PPQ0.0000000 NA 155430 14.28 38.2 AS2 DHA+PPQ0.0000000 NA 21478 15.67 38 AS2 DHA+PPQ0.0000000 NA 59911 17.60 37.5 AS4 DHA+PPQ0.0000000 NA 76490 16.50 38 AS4 DHA+PPQ0.0000000 NA 19342 15.27 38.1 AS2 DHA+PPQ0.0000000 NA 13565 16.03 37.8 AS2 DHA+PPQ0.0000000 NA 91814 16.33 37.1 AS4 DHA+PPQ0.0000000 NA 47477 16.50 37.8 AS4 DHA+PPQ0.0000000 NA 50114 16.83 37.9 AS4 DHA+PPQ0.0000000 NA 29014 18.25 37 AS2 DHA+PPQ0.0000000 NA 6971 18.42 36.6 AS4 DHA+PPQ0.0000000 NA 9294 12.75 37.6 AS4 DHA+PPQ0.0000000 NA 37178 16.92 37.5 AS2 DHA+PPQ0.0000000 NA 47226 12.40 39.5 AS4 DHA+PPQ0.0000000 NA 50114 16.25 37 AS2 DHA+PPQ0.0000000 NA 43960 17.15 37.5 AS4 DHA+PPQ0.0000000 NA 14758 16.68 36.8 AS4 DHA+PPQ0.0000000 NA 48984 16.95 37.5 AS4 DHA+PPQ0.0000000 NA 94514 17.22 37 AS2 DHA+PPQ0.0000000 NA 57776 17.67 39.5 AS4 DHA+PPQ0.0000000 NA 32970 13.58 39.2 AS2 DHA+PPQ0.0020925 -9 15292 14.00 37.4 AS2 DHA+PPQ0.0012473 -10 38482 14.23 38.2 AS2 DHA+PPQ0.0000000 NA 22382 13.90 36.2 AS2 DHA+PPQ0.0000000 NA 33410 14.12 40 AS4 DHA+PPQ0.0000000 NA 31023 14.58 36 AS2 DHA+PPQ0.0000000 NA 30144 16.83 37 AS2 DHA+PPQ0.0000000 NA 28888 17.23 39 AS4 DHA+PPQ

Page 38 of 135


Field site

color





1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 22382 17.77 37.5 AS2 DHA+PPQ0.0000000 NA 52752 15.90 38 AS4 DHA+PPQ0.0000000 NA 93070 14.03 37.5 AS2 DHA+PPQ0.0000000 NA 10550 16.50 38.5 AS2 DHA+PPQ0.0000000 NA 36989 15.60 39 AS4 DHA+PPQ0.0000000 NA 23864 14.92 37 AS4 DHA+PPQ0.0000000 NA 23173 15.63 36.8 AS2 DHA+PPQ0.0000000 NA 13188 15.73 37 AS2 DHA+PPQ0.0000000 NA 7385 13.97 37 AS2 DHA+PPQ0.0000000 NA 20347 17.12 40 AS2 DHA+PPQ0.0000000 NA 25120 15.82 38 AS2 DHA+PPQ0.0000000 NA 35796 16.17 38.5 AS4 DHA+PPQ0.0000000 NA 16579 11.23 37.9 AS2 DHA+PPQ0.0000000 NA 50554 13.87 39.5 AS2 DHA+PPQ0.0000000 NA 38182 16.53 37.5 AS4 DHA+PPQ0.0000000 NA 18652 12.33 38 AS4 DHA+PPQ0.0000000 NA 31350 14.20 38.7 AS4 DHA+PPQ0.0000000 NA 9345 16.83 37.7 AS4 DHA+PPQ0.0000000 NA 38434 12.82 38.5 AS2 DHA+PPQ0.0000000 NA 71027 17.82 39 AS2 DHA+PPQ0.0000000 NA 11304 15.17 37 AS2 DHA+PPQ0.0000000 NA 49110 11.23 39.8 AS4 DHA+PPQ0.0000000 NA 41762 15.50 39.5 AS4 DHA+PPQ0.0000000 NA 17144 13.97 38 AS4 DHA+PPQ0.0000000 NA 16265 13.68 38 AS2 DHA+PPQ0.0000000 NA 20347 17.43 36.6 AS2 DHA+PPQ0.0000000 NA 9797 16.40 40 AS4 DHA+PPQ0.0055887 -7 7730 16.70 38 AS4 DHA+PPQ0.0000000 NA 23738 13.35 38 AS4 DHA+PPQ0.0001972 -12 40577 16.70 37.5 AS2 DHA+PPQ0.0000000 NA 35796 12.17 37 AS2 DHA+PPQ0.0000000 NA 59760 12.48 38.3 AS4 DHA+PPQ0.0013252 -10 7244 12.75 37.6 AS2 DHA+PPQ0.0000000 NA 8541 14.58 39 AS4 DHA+PPQ0.0000000 NA 11932 14.83 39 AS4 NA0.0004452 -11 35938 16.08 39 AS4 DHA+PPQ0.1111111 -3 41825 13.25 39.5 AS2 DHA+PPQ0.0000000 NA 46974 15.20 38.3 AS4 DHA+PPQ0.0000000 NA 52752 15.48 38.1 AS2 DHA+PPQ0.0000000 NA 51433 16.03 38.6 AS2 DHA+PPQ

Page 39 of 135


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color

KH003-104 213613 Cambodia Ratanakiri KH3KH003-105 214127 Cambodia Ratanakiri KH3KH003-107 213626 Cambodia Ratanakiri KH3KH003-109 215861 Cambodia Ratanakiri KH3KH003-110 215881 Cambodia Ratanakiri KH3KH003-111 215899 Cambodia Ratanakiri KH3KH003-112 215909 Cambodia Ratanakiri KH3KH003-113 215956 Cambodia Ratanakiri KH3KH003-114 215706 Cambodia Ratanakiri KH3KH003-115 215950 Cambodia Ratanakiri KH3KH003-116 215933 Cambodia Ratanakiri KH3KH003-117 215718 Cambodia Ratanakiri KH3KH003-118 215940 Cambodia Ratanakiri KH3KH003-119 215723 Cambodia Ratanakiri KH3KH003-120 216172 Cambodia Ratanakiri KH3KH004-001 182486 Cambodia Pailin KH4KH004-002 182505 Cambodia Pailin KH4KH004-005 182576 Cambodia Pailin KH4KH004-007 182409 Cambodia Pailin KH4KH004-008 183791 Cambodia Pailin KH4KH004-012 183632 Cambodia Pailin KH4KH004-013 195809 Cambodia Pailin KH4KH004-014 195808 Cambodia Pailin KH4KH004-015 183725 Cambodia Pailin KH4KH004-016 195807 Cambodia Pailin KH4KH004-018 183504 Cambodia Pailin KH4KH004-019 183551 Cambodia Pailin KH4KH004-020 183564 Cambodia Pailin KH4KH004-021 195803 Cambodia Pailin KH4KH004-022 195804 Cambodia Pailin KH4KH004-023 195684 Cambodia Pailin KH4KH004-024 195802 Cambodia Pailin KH4KH004-025 195801 Cambodia Pailin KH4KH004-027 195641 Cambodia Pailin KH4KH004-028 195806 Cambodia Pailin KH4KH004-030 195872 Cambodia Pailin KH4KH004-031 195835 Cambodia Pailin KH4KH004-032 195864 Cambodia Pailin KH4KH004-033 195886 Cambodia Pailin KH4KH004-034 196276 Cambodia Pailin KH4




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 129305 15.17 37.2 AS4 DHA+PPQ0.0000000 NA 26941 18.00 37 AS2 DHA+PPQ0.0000000 NA 10676 13.42 37 AS2 DHA+PPQ0.0000000 NA 31086 15.15 38 AS4 DHA+PPQ0.0000000 NA 67824 14.00 40 AS4 DHA+PPQ0.0000000 NA 11806 18.13 39 AS4 DHA+PPQ0.0000000 NA 49738 15.73 40 AS4 DHA+PPQ0.0000000 NA 27130 12.83 41 AS2 DHA+PPQ0.0000000 NA 12560 14.00 40 AS4 DHA+PPQ0.0000000 NA 26941 15.47 38 AS2 DHA+PPQ0.0000000 NA 16202 9.83 36.7 AS2 DHA+PPQ0.0000000 NA 15072 15.13 38 AS4 DHA+PPQ0.0000000 NA 17144 16.30 38 AS4 DHA+PPQ0.0000000 NA 15700 17.85 40 AS2 DHA+PPQ0.0000000 NA 6330 13.97 38.3 AS2 DHA+PPQ0.0000000 NA 54071 15.35 38.2 AS4 DHA+PPQ0.0000000 NA 12058 12.30 37.9 AS4 DHA+PPQ0.0000000 NA 7536 18.00 40.3 AS4 DHA+PPQ0.0000000 NA 41147 14.70 39.9 AS4 DHA+PPQ0.0000000 NA 20046 15.85 37.1 AS4 NA0.0000000 NA 25120 18.08 38.4 AS4 DHA+PPQ0.0019264 -9 20764 17.75 38 AS4 DHA+PPQ0.0000000 NA 15449 17.03 39.3 AS4 DHA+PPQ0.0000000 NA 50868 14.20 39.9 AS4 NA0.0005867 -11 13636 10.33 37.4 AS4 DHA+PPQ0.0129538 -6 46318 16.60 37.6 AS4 DHA+PPQ0.0000000 NA 32468 16.83 38.1 AS4 DHA+PPQ0.0000000 NA 35168 11.17 37.5 AS4 DHA+PPQ0.0013391 -10 11948 13.62 39.2 AS4 DHA+PPQ0.0172144 -6 5112 12.05 38.5 AS4 DHA+PPQ0.0000000 NA 76679 13.43 37.4 AS4 DHA+PPQ0.0000000 NA 21540 15.40 39.2 AS4 DHA+PPQ0.0000000 NA 20661 17.07 37.1 AS4 DHA+PPQ0.0000000 NA 22608 10.22 39.5 AS4 DHA+PPQ0.0000000 NA 34666 14.35 38.8 AS4 DHA+PPQ0.0000000 NA 31777 10.48 38.3 AS4 DHA+PPQ0.0000000 NA 78751 14.92 38.1 AS4 DHA+PPQ0.0000000 NA 19342 18.35 39.1 AS4 DHA+PPQ0.0000000 NA 15826 18.95 39.1 AS4 DHA+PPQ0.0000000 NA 28888 16.52 39.3 AS4 DHA+PPQ

Page 40 of 135


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color

KH004-035 196308 Cambodia Pailin KH4KH004-036 196328 Cambodia Pailin KH4KH004-037 196400 Cambodia Pailin KH4KH004-038 196438 Cambodia Pailin KH4KH004-039 196449 Cambodia Pailin KH4KH004-040 196014 Cambodia Pailin KH4KH004-041 196037 Cambodia Pailin KH4KH004-042 196050 Cambodia Pailin KH4KH004-043 209174 Cambodia Pailin KH4KH004-044 209188 Cambodia Pailin KH4KH004-045 209199 Cambodia Pailin KH4KH004-046 209357 Cambodia Pailin KH4KH004-047 209370 Cambodia Pailin KH4KH004-048 209372 Cambodia Pailin KH4KH004-049 209423 Cambodia Pailin KH4KH004-051 195514 Cambodia Pailin KH4KH004-052 195526 Cambodia Pailin KH4KH004-053 209622 Cambodia Pailin KH4KH004-054 208981 Cambodia Pailin KH4KH004-055 208996 Cambodia Pailin KH4KH004-056 209469 Cambodia Pailin KH4KH004-057 209497 Cambodia Pailin KH4KH004-058 209744 Cambodia Pailin KH4KH004-059 209769 Cambodia Pailin KH4KH004-060 209803 Cambodia Pailin KH4KH004-061 209874 Cambodia Pailin KH4KH004-062 209919 Cambodia Pailin KH4KH004-063 209936 Cambodia Pailin KH4KH004-064 209713 Cambodia Pailin KH4KH004-065 209716 Cambodia Pailin KH4KH004-066 209732 Cambodia Pailin KH4KH004-067 209246 Cambodia Pailin KH4KH004-068 222084 Cambodia Pailin KH4KH004-069 222103 Cambodia Pailin KH4KH004-070 222135 Cambodia Pailin KH4KH004-071 222257 Cambodia Pailin KH4KH004-073 209100 Cambodia Pailin KH4KH004-073 222060 Cambodia Pailin KH4KH004-074 209121 Cambodia Pailin KH4KH004-075 209127 Cambodia Pailin KH4




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0007955 -10 20112 11.73 39.9 AS4 DHA+PPQ0.0001814 -12 44094 10.88 37.7 AS4 DHA+PPQ0.0000000 NA 110716 15.30 39.8 AS4 DHA+PPQ0.0000000 NA 35922 11.53 38.7 AS4 DHA+PPQ0.0000000 NA 13502 13.60 39.9 AS4 DHA+PPQ0.0000000 NA 47477 14.83 38.8 AS4 DHA+PPQ0.0000000 NA 12560 13.97 37.3 AS4 DHA+PPQ0.0000000 NA 121518 10.58 39.5 AS4 DHA+PPQ0.0000000 NA 22608 10.88 37.2 AS4 DHA+PPQ0.0000000 NA 5526 14.02 37.3 AS4 DHA+PPQ0.0000000 NA 69331 15.43 40.2 AS4 DHA+PPQ0.0005053 -11 31667 14.77 38.7 AS4 DHA+PPQ0.0002653 -12 30152 12.65 39.6 AS4 DHA+PPQ0.0000000 NA 32656 12.95 38.6 AS4 DHA+PPQ0.0000000 NA 31651 17.67 39.4 AS4 DHA+PPQ0.0042918 -8 1864 16.08 37.3 AS4 DHA+PPQ0.0000000 NA 7536 11.63 39.3 AS4 DHA+PPQ0.0000000 NA 37680 11.30 39 AS4 DHA+PPQ0.0000000 NA 7913 15.65 38.7 AS4 DHA+PPQ0.0000000 NA 194994 13.50 39.6 AS4 DHA+PPQ0.0008554 -10 46763 18.28 37.5 AS4 DHA+PPQ0.0000000 NA 7159 12.12 37.3 AS4 DHA+PPQ0.0000000 NA 40192 13.48 39 AS4 DHA+PPQ0.0000000 NA 5526 9.82 39.8 AS4 DHA+PPQ0.0000000 NA 97214 11.97 38.8 AS4 DHA+PPQ0.0000000 NA 10802 11.33 39.1 AS4 DHA+PPQ0.0000000 NA 12246 11.27 40.5 AS4 DHA+PPQ0.0000000 NA 30772 10.32 37.4 AS4 DHA+PPQ0.0000000 NA 48921 16.08 39.1 AS4 DHA+PPQ0.0000000 NA 22106 16.42 38.1 AS4 DHA+PPQ0.0000000 NA 12309 11.97 39.1 AS4 DHA+PPQ0.0100521 -7 43772 14.92 38.2 AS4 DHA+PPQ0.0000000 NA 48984 14.33 38.8 AS4 DHA+PPQ0.0000000 NA 5275 13.67 37.6 AS4 DHA+PPQ0.0000000 NA 12874 18.25 38.7 AS4 DHA+PPQ0.0000990 -13 80832 10.97 38.4 AS4 DHA+PPQ0.0000000 NA 10048 15.40 39.2 AS4 DHA+PPQ0.0000000 NA 10048 15.40 39.2 AS4 DHA+PPQ0.0000000 NA 23236 16.82 38.3 AS4 DHA+PPQ0.0000000 NA 10362 10.72 38 AS4 DHA+PPQ

Page 41 of 135


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color

KH004-076 222166 Cambodia Pailin KH4KH004-077 221977 Cambodia Pailin KH4KH004-078 221813 Cambodia Pailin KH4KH004-079 221844 Cambodia Pailin KH4KH004-080 222001 Cambodia Pailin KH4KH004-081 235369 Cambodia Pailin KH4KH004-082 235340 Cambodia Pailin KH4KH004-083 235303 Cambodia Pailin KH4KH004-084 234600 Cambodia Pailin KH4KH004-084 235312 Cambodia Pailin KH4KH004-085 235385 Cambodia Pailin KH4KH004-086 235404 Cambodia Pailin KH4KH004-087 235415 Cambodia Pailin KH4KH004-088 235438 Cambodia Pailin KH4KH004-089 234609 Cambodia Pailin KH4KH004-090 234627 Cambodia Pailin KH4KH004-091 231253 Cambodia Pailin KH4KH004-092 231270 Cambodia Pailin KH4KH004-093 231281 Cambodia Pailin KH4KH004-094 234486 Cambodia Pailin KH4KH004-095 234502 Cambodia Pailin KH4KH004-096 234541 Cambodia Pailin KH4KH004-097 234684 Cambodia Pailin KH4KH004-098 234692 Cambodia Pailin KH4KH004-099 234731 Cambodia Pailin KH4KH004-100 231370 Cambodia Pailin KH4LA001-001 189212 Laos Attapeu LALA001-002 189217 Laos Attapeu LALA001-003 189222 Laos Attapeu LALA001-004 189229 Laos Attapeu LALA001-005 189233 Laos Attapeu LALA001-006 189238 Laos Attapeu LALA001-007 189243 Laos Attapeu LALA001-008 189312 Laos Attapeu LALA001-009 189338 Laos Attapeu LALA001-010 189344 Laos Attapeu LALA001-011 189348 Laos Attapeu LALA001-012 189352 Laos Attapeu LALA001-013 189360 Laos Attapeu LALA001-015 189363 Laos Attapeu LA




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 17521 11.17 40.8 AS4 DHA+PPQ0.0363719 -5 14077 17.15 38.3 AS4 DHA+PPQ0.0553289 -4 5784 16.58 37.9 AS4 DHA+PPQ0.0000000 NA 21101 14.03 39.7 AS4 DHA+PPQ0.0000000 NA 16265 17.13 39.7 AS4 DHA+PPQ0.0000000 NA 17584 13.87 38.3 AS4 DHA+PPQ0.0000000 NA 54259 13.33 38.3 AS4 DHA+PPQ0.0000000 NA 51308 10.50 38.3 AS4 DHA+PPQ0.0005441 -11 29406 20.90 36.5 AS4 DHA+PPQ0.0005441 -11 29406 20.90 36.5 AS4 DHA+PPQ0.0000000 NA 5401 13.23 38.7 AS4 DHA+PPQ0.0011781 -10 6790 11.28 38.2 AS4 DHA+PPQ0.0000000 NA 13188 14.30 37.5 AS4 DHA+PPQ0.0000000 NA 43772 13.53 38.5 AS4 DHA+PPQ0.0000000 NA 41448 12.63 37.9 AS4 DHA+PPQ0.0000000 NA 6594 13.65 38.8 AS4 DHA+PPQ0.0000000 NA 51245 13.67 39.6 AS4 DHA+PPQ0.0000000 NA 7724 18.52 37.4 AS4 DHA+PPQ0.0006241 -11 12819 15.82 39.7 AS4 DHA+PPQ0.0000000 NA 21603 17.72 37.7 AS4 DHA+PPQ0.0007955 -10 20112 20.02 37 AS4 DHA+PPQ0.0000000 NA 35419 10.60 39.3 AS4 DHA+PPQ0.0000000 NA 58027 16.78 38.5 AS4 DHA+PPQ0.0000000 NA 30395 16.68 38 AS4 DHA+PPQ0.0000000 NA 17082 18.03 38 AS4 DHA+PPQ0.0000000 NA 56520 10.40 38.6 AS4 DHA+PPQ0.0000000 NA 26250 11.83 37.3 AS2 AM+LUM0.0000000 NA 3843 9.92 38 AS4 AM+LUM0.0000000 NA 10048 10.67 37.9 AS2 AM+LUM0.0037017 -8 27230 14.67 37.7 AS4 AM+LUM0.0000000 NA 13565 11.50 36.9 AS2 AM+LUM0.0000000 NA 10048 12.25 39.2 AS4 AM+LUM0.0000000 NA 15826 17.08 38.1 AS4 AM+LUM0.0000000 NA 26250 17.17 37.4 AS4 AM+LUM0.0000000 NA 35796 11.83 37 AS2 AM+LUM0.0000000 NA 12434 14.00 38.5 AS4 AM+LUM0.0000000 NA 49738 11.92 39.8 AS2 AM+LUM0.0000000 NA 18463 12.92 37.9 AS2 AM+LUM0.0000000 NA 14130 14.83 37.7 AS2 AM+LUM0.0000000 NA 26941 10.50 36.9 AS2 AM+LUM

Page 42 of 135


Field site

color

LA001-016 189365 Laos Attapeu LALA001-018 189380 Laos Attapeu LALA001-019 189388 Laos Attapeu LALA001-020 189390 Laos Attapeu LALA001-022 189396 Laos Attapeu LALA001-023 189401 Laos Attapeu LALA001-024 189407 Laos Attapeu LALA001-034 199975 Laos Attapeu LALA001-038 199891 Laos Attapeu LALA001-041 199910 Laos Attapeu LALA001-042 199911 Laos Attapeu LALA001-043 199926 Laos Attapeu LALA001-044 199927 Laos Attapeu LALA001-045 199928 Laos Attapeu LALA001-046 199929 Laos Attapeu LALA001-047 199934 Laos Attapeu LALA001-049 199943 Laos Attapeu LALA001-050 199948 Laos Attapeu LALA001-051 199954 Laos Attapeu LALA001-052 199955 Laos Attapeu LALA001-062 199962 Laos Attapeu LALA001-063 199966 Laos Attapeu LALA001-064 199971 Laos Attapeu LALA001-065 200185 Laos Attapeu LALA001-066 200191 Laos Attapeu LALA001-068 200198 Laos Attapeu LALA001-069 200203 Laos Attapeu LALA001-070 200213 Laos Attapeu LALA001-071 200208 Laos Attapeu LALA001-072 200218 Laos Attapeu LALA001-073 200226 Laos Attapeu LALA001-074 200229 Laos Attapeu LALA001-075 200236 Laos Attapeu LALA001-076 200337 Laos Attapeu LALA001-077 200088 Laos Attapeu LALA001-078 200092 Laos Attapeu LALA001-079 200097 Laos Attapeu LALA001-080 200103 Laos Attapeu LALA001-081 200108 Laos Attapeu LALA001-082 200113 Laos Attapeu LA




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 8101 12.00 39.5 AS4 AM+LUM0.0000000 NA 8177 17.58 38.1 AS4 AM+LUM0.0000000 NA 13188 9.58 38.8 AS4 AM+LUM0.0158796 -6 9572 17.50 37.7 AS2 AM+LUM0.0000000 NA 10990 12.00 37 AS4 AM+LUM0.0000000 NA 19594 11.50 39.6 AS4 AM+LUM0.0006210 -11 12882 17.75 40.2 AS2 AM+LUM0.0011162 -10 7167 11.50 40.1 AS4 AM+LUM0.0000000 NA 43520 12.67 36.6 AS2 AM+LUM0.0000000 NA 16579 11.57 37.2 AS4 AM+LUM0.0000000 NA 33158 11.60 38 AS4 AM+LUM0.0000000 NA 16956 11.83 36.5 AS4 AM+LUM0.0000000 NA 99287 11.92 38.2 AS4 AM+LUM0.0000000 NA 15386 12.00 36.9 AS2 AM+LUM0.0000000 NA 37178 12.08 39.5 AS2 AM+LUM0.0000000 NA 40192 17.42 39.2 AS4 AM+LUM0.0000000 NA 59346 15.50 38.2 AS2 AM+LUM0.0000000 NA 45216 15.00 38.9 AS2 AM+LUM0.0000000 NA 34666 11.75 38.6 AS2 AM+LUM0.0000000 NA 23173 11.92 38.5 AS2 AM+LUM0.0000000 NA 10048 12.50 36.6 AS2 AM+LUM0.0003032 -12 31661 11.92 39.2 AS4 AM+LUM0.0000000 NA 36047 12.58 37.5 AS2 AM+LUM0.0000000 NA 56520 11.50 36.9 AS4 AM+LUM0.0000000 NA 19217 17.75 37.8 AS4 AM+LUM0.0000000 NA 29390 15.50 39.4 AS2 AM+LUM0.0000000 NA 37806 11.50 36.9 AS4 AM+LUM0.0000000 NA 19594 17.42 37.2 AS2 AM+LUM0.0000000 NA 17584 17.50 37.7 AS4 AM+LUM0.0000000 NA 15072 13.58 39.6 AS2 AM+LUM0.0000000 NA 10174 11.50 39.2 AS2 AM+LUM0.0000000 NA 6971 17.17 36.4 AS2 AM+LUM0.0046730 -8 25680 10.00 36.4 AS4 AM+LUM0.0000000 NA 45907 17.00 39.6 AS4 AM+LUM0.0000000 NA 61042 13.92 38.8 AS4 AM+LUM0.0000000 NA 45216 11.50 39.1 AS4 AM+LUM0.0000000 NA 22608 12.67 39.3 AS2 AM+LUM0.0000000 NA 74355 18.08 38.8 AS2 AM+LUM0.0000000 NA 98910 12.25 38.6 AS2 AM+LUM0.0000000 NA 42704 11.50 40.7 AS2 AM+LUM

Page 43 of 135


Field site

color

LA001-083 200116 Laos Attapeu LALA001-084 200122 Laos Attapeu LALA001-085 200125 Laos Attapeu LALA001-086 200384 Laos Attapeu LALA001-091 200137 Laos Attapeu LALA001-092 200141 Laos Attapeu LALA001-093 200144 Laos Attapeu LALA001-094 200151 Laos Attapeu LALA001-095 200157 Laos Attapeu LALA001-096 200160 Laos Attapeu LALA001-097 200165 Laos Attapeu LALA001-098 200169 Laos Attapeu LALA001-099 200170 Laos Attapeu LALA001-100 200171 Laos Attapeu LALA001-101 200172 Laos Attapeu LALA001-102 217666 Laos Attapeu LALA001-103 217676 Laos Attapeu LALA001-105 217679 Laos Attapeu LALA001-106 217684 Laos Attapeu LALA001-107 217689 Laos Attapeu LALA001-108 217691 Laos Attapeu LALA001-109 217696 Laos Attapeu LALA001-110 217701 Laos Attapeu LALA001-111 217706 Laos Attapeu LALA001-112 199992 Laos Attapeu LALA001-113 199999 Laos Attapeu LALA001-114 200006 Laos Attapeu LALA001-115 199996 Laos Attapeu LALA001-116 200010 Laos Attapeu LALA001-117 200023 Laos Attapeu LALA001-118 200020 Laos Attapeu LALA001-119 200017 Laos Attapeu LALA001-120 200032 Laos Attapeu LAMM001-001 210552 Myanmar Shwe Kyin MMMM001-002 210570 Myanmar Shwe Kyin MMMM001-003 210579 Myanmar Shwe Kyin MMMM001-004 210609 Myanmar Shwe Kyin MMMM001-005 210248 Myanmar Shwe Kyin MMMM001-005 210634 Myanmar Shwe Kyin MMMM001-006 210247 Myanmar Shwe Kyin MM




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 33284 14.17 39.3 AS4 AM+LUM0.0000000 NA 15072 13.25 39.3 AS2 AM+LUM0.0000000 NA 48042 15.17 37.5 AS4 AM+LUM0.0000000 NA 25120 11.50 36.9 AS4 AM+LUM0.0000000 NA 7724 12.00 37.8 AS2 AM+LUM0.0000000 NA 10852 17.50 38.5 AS2 AM+LUM0.0000000 NA 31023 20.50 39.1 AS4 AM+LUM0.0000000 NA 30370 11.50 38.3 AS4 AM+LUM0.0000000 NA 35268 12.50 39.9 AS2 AM+LUM0.0000000 NA 11304 12.50 39.2 AS4 AM+LUM0.0000000 NA 6594 12.50 37.8 AS4 AM+LUM0.0000000 NA 39564 17.00 38.1 AS4 AM+LUM0.0000000 NA 17144 17.17 38 AS2 AM+LUM0.0000000 NA 14318 17.25 36.1 AS2 AM+LUM0.0000000 NA 50114 17.33 36.1 AS4 AM+LUM0.0000000 NA 13628 12.50 39.6 AS4 AM+LUM0.0000000 NA 23236 17.00 38.9 AS2 AM+LUM0.0000000 NA 14318 17.00 37.5 AS4 AM+LUM0.0000000 NA 5024 17.08 39.7 AS4 AM+LUM0.0000000 NA 65061 11.50 40.2 AS2 AM+LUM0.0000000 NA 26250 12.50 37.6 AS4 AM+LUM0.0000000 NA 98910 12.67 36.4 AS4 AM+LUM0.0000000 NA 5275 12.75 38.3 AS2 AM+LUM0.0000000 NA 87920 12.50 36.9 AS2 AM+LUM0.0000000 NA 27632 11.00 39.9 AS2 AM+LUM0.0000000 NA 4635 12.25 38.6 AS2 AM+LUM0.0000000 NA 4748 12.33 39.2 AS2 AM+LUM0.0000000 NA 34289 12.50 36.6 AS4 AM+LUM0.0000000 NA 18463 15.75 38.7 AS2 AM+LUM0.0000000 NA 25748 11.50 39.9 AS4 AM+LUM0.0000000 NA 15449 11.67 39.2 AS4 AM+LUM0.0000000 NA 90683 11.83 39.7 AS2 AM+LUM0.0000000 NA 43960 15.00 39.5 AS2 AM+LUM0.0000000 NA 151285 21.00 39.1 AS2 AM+LUM0.0000000 NA 87543 14.83 40.5 AS2 AM+LUM0.0000000 NA 210003 18.17 37.9 AS2 AM+LUM0.0000000 NA 95456 19.08 39.6 AS4 AM+LUM0.0000000 NA 41636 13.00 39.6 AS2 AM+LUM0.0000000 NA 41636 13.00 39.6 AS2 AM+LUM0.0000000 NA 36926 13.00 38.6 AS4 AM+LUM

Page 44 of 135


Field site

color

MM001-006 210635 Myanmar Shwe Kyin MMMM001-007 210268 Myanmar Shwe Kyin MMMM001-008 210292 Myanmar Shwe Kyin MMMM001-009 210293 Myanmar Shwe Kyin MMMM001-010 209962 Myanmar Shwe Kyin MMMM001-011 210452 Myanmar Shwe Kyin MMMM001-012 210464 Myanmar Shwe Kyin MMMM001-013 210204 Myanmar Shwe Kyin MMMM001-014 210473 Myanmar Shwe Kyin MMMM001-015 210053 Myanmar Shwe Kyin MMMM001-016 210216 Myanmar Shwe Kyin MMMM001-017 210406 Myanmar Shwe Kyin MMMM001-018 210485 Myanmar Shwe Kyin MMMM001-019 210536 Myanmar Shwe Kyin MMMM001-020 210233 Myanmar Shwe Kyin MMMM001-021 210849 Myanmar Shwe Kyin MMMM001-022 210850 Myanmar Shwe Kyin MMMM001-023 210898 Myanmar Shwe Kyin MMMM001-024 210906 Myanmar Shwe Kyin MMMM001-025 210919 Myanmar Shwe Kyin MMMM001-026 210930 Myanmar Shwe Kyin MMMM001-027 209977 Myanmar Shwe Kyin MMMM001-028 209995 Myanmar Shwe Kyin MMMM001-029 209996 Myanmar Shwe Kyin MMMM001-030 210013 Myanmar Shwe Kyin MMMM001-031 210820 Myanmar Shwe Kyin MMMM001-032 210821 Myanmar Shwe Kyin MMMM001-033 210414 Myanmar Shwe Kyin MMMM001-034 210436 Myanmar Shwe Kyin MMMM001-035 210437 Myanmar Shwe Kyin MMMM001-036 210073 Myanmar Shwe Kyin MMMM001-037 210105 Myanmar Shwe Kyin MMMM001-038 219988 Myanmar Shwe Kyin MMMM001-039 220001 Myanmar Shwe Kyin MMMM001-040 220027 Myanmar Shwe Kyin MMMM001-041 210654 Myanmar Shwe Kyin MMMM001-042 210666 Myanmar Shwe Kyin MMMM001-043 220297 Myanmar Shwe Kyin MMMM001-044 220361 Myanmar Shwe Kyin MMMM001-045 220374 Myanmar Shwe Kyin MM




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 36926 13.00 38.6 AS4 AM+LUM0.0000000 NA 50868 20.33 37.8 AS4 AM+LUM0.0000000 NA 121016 18.33 38 AS4 AM+LUM0.0000000 NA 19217 18.33 39.5 AS2 AM+LUM0.0000000 NA 40569 10.67 38.9 AS2 AM+LUM0.0000000 NA 81389 14.50 40 AS4 AM+LUM0.0066918 -7 13150 18.50 39.7 AS4 AM+LUM0.0000000 NA 23676 15.67 37.9 AS2 AM+LUM0.0000000 NA 37680 18.92 39.2 AS4 AM+LUM0.0000000 NA 102615 14.10 39.4 AS2 AM+LUM0.0000000 NA 30898 22.27 39.8 AS4 AM+LUM0.0000000 NA 15826 19.27 37.6 AS4 AM+LUM0.0000000 NA 30521 11.67 37.6 AS4 AM+LUM0.0000000 NA 70336 12.13 38.7 AS2 AM+LUM0.0000000 NA 111030 20.37 37.8 AS2 AM+LUM0.0000000 NA 54008 21.92 38.6 AS4 AM+LUM0.0000000 NA 57776 21.92 37.8 AS2 AM+LUM0.0000000 NA 102992 10.83 37.8 AS4 AM+LUM0.0000000 NA 106886 17.08 39.3 AS4 AM+LUM0.0952381 -3 105504 13.68 37.9 AS2 AM+LUM0.0000000 NA 68326 20.03 37.8 AS2 AM+LUM0.0000000 NA 23738 12.23 38.2 AS4 AM+LUM0.0000000 NA 9797 22.03 38.1 AS4 AM+LUM0.0000000 NA 35796 22.03 37.9 AS4 AM+LUM0.0000000 NA 22608 15.33 37.9 AS4 AM+LUM0.1666667 -3 14695 16.67 38.2 AS2 AM+LUM0.1111111 -3 23173 16.67 39 AS2 AM+LUM0.0000000 NA 18024 10.92 37.8 AS2 AM+LUM0.0000000 NA 12560 19.47 37.8 AS2 AM+LUM0.0000000 NA 5784 19.47 37.9 AS2 AM+LUM0.0000000 NA 44776 18.17 38.3 AS4 AM+LUM0.0000000 NA 23236 12.47 37.8 AS4 AM+LUM0.0000000 NA 35105 20.42 37.9 AS4 AM+LUM0.0000000 NA 50554 13.73 38 AS2 AM+LUM0.0000000 NA 24492 19.58 38.1 AS2 AM+LUM0.0000000 NA 39187 13.77 37.9 AS2 AM+LUM0.0000000 NA 31651 13.13 38.5 AS4 AM+LUM0.0000000 NA 8960 14.60 38.6 AS4 AM+LUM0.0007513 -10 10648 11.37 38 AS4 AM+LUM0.0000000 NA 74606 14.47 38.8 AS4 AM+LUM

Page 45 of 135


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color

MM001-046 220086 Myanmar Shwe Kyin MMMM001-047 220142 Myanmar Shwe Kyin MMMM001-048 220154 Myanmar Shwe Kyin MMMM001-049 220167 Myanmar Shwe Kyin MMMM001-050 220179 Myanmar Shwe Kyin MMMM001-051 220192 Myanmar Shwe Kyin MMMM001-052 220204 Myanmar Shwe Kyin MMMM001-053 220216 Myanmar Shwe Kyin MMMM001-054 220387 Myanmar Shwe Kyin MMMM001-055 220420 Myanmar Shwe Kyin MMMM001-056 220431 Myanmar Shwe Kyin MMMM001-057 220468 Myanmar Shwe Kyin MMMM001-058 220475 Myanmar Shwe Kyin MMMM001-059 239513 Myanmar Shwe Kyin MMMM001-060 239621 Myanmar Shwe Kyin MMMM001-061 239608 Myanmar Shwe Kyin MMMM001-062 239568 Myanmar Shwe Kyin MMMM001-063 239538 Myanmar Shwe Kyin MMMM001-064 239536 Myanmar Shwe Kyin MMMM001-065 239532 Myanmar Shwe Kyin MMMM001-066 239872 Myanmar Shwe Kyin MMMM001-067 239862 Myanmar Shwe Kyin MMMM001-068 239842 Myanmar Shwe Kyin MMMM001-069 239841 Myanmar Shwe Kyin MMMM001-070 239803 Myanmar Shwe Kyin MMMM001-071 239791 Myanmar Shwe Kyin MMMM001-072 239781 Myanmar Shwe Kyin MMMM001-073 239769 Myanmar Shwe Kyin MMMM001-074 239719 Myanmar Shwe Kyin MMMM001-075 239706 Myanmar Shwe Kyin MMMM001-076 238755 Myanmar Shwe Kyin MMMM001-077 238774 Myanmar Shwe Kyin MMMM001-078 238800 Myanmar Shwe Kyin MMMM001-079 238813 Myanmar Shwe Kyin MMMM001-080 238824 Myanmar Shwe Kyin MMTH004-001 188821 Thailand Mae Sot TH4TH004-002 188831 Thailand Mae Sot TH4TH004-003 188839 Thailand Mae Sot TH4TH004-004 188843 Thailand Mae Sot TH4TH004-005 188849 Thailand Mae Sot TH4




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 6056 17.07 38.2 AS2 AM+LUM0.0000000 NA 25622 12.38 37.9 AS4 AM+LUM0.0000000 NA 15260 18.33 38.1 AS4 AM+LUM0.0000000 NA 92316 11.45 38.7 AS4 AM+LUM0.0000000 NA 105504 14.27 38.6 AS2 AM+LUM0.0000000 NA 14608 14.13 38.2 AS4 AM+LUM0.0000000 NA 88171 19.82 37.8 AS4 AM+LUM0.0000000 NA 48607 19.15 38.3 AS2 AM+LUM0.0000000 NA 5888 19.15 37.9 AS2 AM+LUM0.0000000 NA 11912 15.48 37.9 AS2 AM+LUM0.0000000 NA 6368 19.30 38.7 AS2 AM+LUM0.0000000 NA 7544 12.42 37.8 AS4 AM+LUM0.0588235 -4 34163 14.27 37.8 AS2 AM+LUM0.0000000 NA 7808 20.30 37.8 AS2 AM+LUM0.0000000 NA 8656 9.50 39 AS2 AM+LUM0.0000000 NA 97968 10.27 38.1 AS2 AM+LUM0.0000000 NA 30898 14.83 38.8 AS2 AM+LUM0.0000000 NA 33912 18.67 38.2 AS2 AM+LUM0.0000000 NA 30395 18.67 38.3 AS2 AM+LUM0.0000000 NA 12296 19.95 37.9 AS4 AM+LUM0.0000000 NA 13472 13.55 39 AS4 AM+LUM0.0000000 NA 53380 15.85 37.9 AS4 AM+LUM0.0000000 NA 5752 12.92 37.8 AS4 AM+LUM0.0000000 NA 37680 12.92 38 AS4 AM+LUM0.0013774 -10 11616 18.28 38 AS2 AM+LUM0.0000000 NA 81954 21.88 37.8 AS2 AM+LUM0.0000000 NA 69080 14.00 39.6 AS2 AM+LUM0.0000000 NA 22106 15.75 38.8 AS4 AM+LUM0.0000000 NA 12811 11.58 39.2 AS4 AM+LUM0.0555556 -4 37303 11.22 37.9 AS4 AM+LUM0.0000000 NA 45907 17.67 38.4 AS4 AM+LUM0.0000000 NA 42955 12.80 37.8 AS2 AM+LUM0.0000000 NA 46974 14.92 38.4 AS2 AM+LUM0.0000000 NA 5320 13.93 38.3 AS2 AM+LUM0.0005903 -11 13552 13.83 38.2 AS4 AM+LUM0.0000000 NA 13502 13.08 37.2 AS4 AS/MQ0.0052798 -8 15152 14.08 37.8 AS2 AS/MQ0.0000000 NA 21101 14.97 37.8 AS4 AS/MQ0.0000000 NA 21603 12.73 37.5 AS4 AS/MQ0.0101688 -7 11801 13.68 36.6 AS4 AS/MQ

Page 46 of 135


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color

TH004-006 188854 Thailand Mae Sot TH4TH004-007 188859 Thailand Mae Sot TH4TH004-008 188864 Thailand Mae Sot TH4TH004-009 189022 Thailand Mae Sot TH4TH004-010 189017 Thailand Mae Sot TH4TH004-011 189014 Thailand Mae Sot TH4TH004-012 188909 Thailand Mae Sot TH4TH004-013 193160 Thailand Mae Sot TH4TH004-014 193059 Thailand Mae Sot TH4TH004-015 193064 Thailand Mae Sot TH4TH004-016 193071 Thailand Mae Sot TH4TH004-017 193072 Thailand Mae Sot TH4TH004-018 193080 Thailand Mae Sot TH4TH004-019 197292 Thailand Mae Sot TH4TH004-020 197303 Thailand Mae Sot TH4TH004-021 197308 Thailand Mae Sot TH4TH004-022 197493 Thailand Mae Sot TH4TH004-023 197312 Thailand Mae Sot TH4TH004-024 197329 Thailand Mae Sot TH4TH004-025 197513 Thailand Mae Sot TH4TH004-026 197512 Thailand Mae Sot TH4TH004-027 197526 Thailand Mae Sot TH4TH004-028 197533 Thailand Mae Sot TH4TH004-028 197344 Thailand Mae Sot TH4TH004-029 197536 Thailand Mae Sot TH4TH004-029 197540 Thailand Mae Sot TH4TH004-030 197381 Thailand Mae Sot TH4TH004-031 197376 Thailand Mae Sot TH4TH004-032 197364 Thailand Mae Sot TH4TH004-033 197363 Thailand Mae Sot TH4TH004-034 197555 Thailand Mae Sot TH4TH004-035 197349 Thailand Mae Sot TH4TH004-036 197356 Thailand Mae Sot TH4TH004-037 197580 Thailand Mae Sot TH4TH004-038 197582 Thailand Mae Sot TH4TH004-039 197583 Thailand Mae Sot TH4TH004-040 197569 Thailand Mae Sot TH4TH004-041 206948 Thailand Mae Sot TH4TH004-042 206949 Thailand Mae Sot TH4TH004-044 206972 Thailand Mae Sot TH4




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 9420 15.30 38.4 AS2 AS/MQ0.0000000 NA 41448 11.92 37 AS2 AS/MQ0.0000000 NA 4584 13.18 36.8 AS2 AS/MQ0.0000000 NA 28888 13.45 37.5 AS2 AS/MQ0.0000000 NA 131880 13.92 40.2 AS4 AS/MQ0.0000000 NA 18903 14.07 39.2 AS4 AS/MQ0.0000000 NA 94514 14.43 39.2 AS4 AS/MQ0.0000000 NA 8101 13.55 38 AS2 AS/MQ0.0000000 NA 68578 12.47 38 AS2 AS/MQ0.0000000 NA 163531 14.93 39.4 AS2 AS/MQ0.0000000 NA 5275 15.90 37.3 AS2 AS/MQ0.0000000 NA 1280 13.87 36.9 AS4 AS/MQ0.0000000 NA 31400 13.53 39.6 AS4 AS/MQ0.0000000 NA 5024 14.92 38.2 AS4 AS/MQ0.0000000 NA 54887 13.47 39.9 AS2 AS/MQ0.0000000 NA 14444 15.08 38.5 AS4 AS/MQ0.0000000 NA 30144 12.55 39.5 AS2 AS/MQ0.0000000 NA 4396 12.45 37 AS4 AS/MQ0.0000000 NA 96461 14.18 38.7 AS2 AS/MQ0.0000000 NA 29704 15.23 37.1 AS2 AS/MQ0.0000000 NA 40506 16.03 37.8 AS4 AS/MQ0.0455927 -4 14739 13.83 36.9 AS4 DHA+PPQ0.0000000 NA 4396 11.30 37.9 AS4 DHA+PPQ0.0000000 NA 2638 11.30 37.9 AS4 DHA+PPQ0.0000000 NA 23173 15.08 39 AS4 AS/MQ0.0000000 NA 23173 15.08 39 AS4 AS/MQ0.0000000 NA 7913 12.07 39.5 AS2 AS/MQ0.0000000 NA 5275 13.50 37.1 AS4 AS/MQ0.0000000 NA 8038 12.10 37 AS2 AS/MQ0.0000000 NA 3768 12.38 36.5 AS4 DHA+PPQ

NA NA NA 14.13 36.9 AS2 AS/MQ0.0000000 NA 19342 14.47 37.2 AS4 AS/MQ0.0000000 NA 21603 12.77 37.4 AS2 AS/MQ0.0000000 NA 15449 13.67 36.9 AS2 AS/MQ0.0000000 NA 54071 14.17 37.5 AS2 AS/MQ0.0000000 NA 50240 14.50 37.5 AS4 AS/MQ0.0000000 NA 20598 15.47 37.7 AS2 AS/MQ0.0000000 NA 5401 11.05 36.9 AS4 AS/MQ0.0000000 NA 28260 14.27 37.7 AS2 AS/MQ0.0070274 -7 13661 14.35 37.7 AS2 AS/MQ

Page 47 of 135


Field site

color





1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 14695 11.38 38.5 AS4 AS/MQ0.0000000 NA 23110 12.30 38.6 AS4 AS/MQ0.0000000 NA 11053 16.10 37.3 AS2 AS/MQ0.0000000 NA 8855 11.28 38 AS2 AS/MQ0.0000000 NA 102866 12.52 40 AS4 AS/MQ0.0000000 NA 13565 12.88 39.3 AS4 AS/MQ0.0000000 NA 22043 16.72 37.2 AS2 AS/MQ0.0000000 NA 13502 13.50 37.8 AS2 AS/MQ0.0000000 NA 4145 14.95 38.5 AS2 AS/MQ0.0014134 -9 16980 15.67 39.4 AS4 AS/MQ0.0000000 NA 35168 16.22 38.5 AS4 AS/MQ0.0000000 NA 54887 11.77 38.7 AS4 AS/MQ0.0000000 NA 54259 15.00 37.7 AS2 AS/MQ0.0000000 NA 18463 17.07 37.9 AS4 AS/MQ0.0000000 NA 1808 17.55 37.4 AS2 AS/MQ0.0001569 -13 51002 12.18 36 AS2 AS/MQ0.0000000 NA 39187 14.88 38.2 AS4 AS/MQ0.0000000 NA 10990 15.43 37.2 AS2 DHA+PPQ0.0000000 NA 9546 13.28 38 AS2 AS/MQ0.0003841 -11 41652 12.67 38.9 AS4 AS/MQ0.0000000 NA 54887 16.27 38.3 AS4 PQ AND AS+MQ(0.0000000 NA 6782 12.07 36.9 AS4 DHA+PPQ0.0000000 NA 46346 13.82 39 AS2 AS/MQ0.0000000 NA 51998 14.27 37.9 AS4 AS/MQ0.0000000 NA 36926 15.15 37.5 AS4 AS/MQ0.0000000 NA 50177 12.42 37 AS4 DHA+PPQ0.0000000 NA 44148 12.18 37.8 AS2 AS/MQ0.0000000 NA 11618 11.40 36.8 AS2 AS/MQ0.0000000 NA 25622 14.58 38.1 AS2 AS/MQ0.0000000 NA 8541 15.13 36.9 AS2 AS/MQ0.0000000 NA 16956 13.65 37.6 AS4 DHA+PPQ0.0000000 NA 8792 14.00 37.7 AS4 AS/MQ0.0000000 NA 67824 11.92 37.5 AS2 AS/MQ0.0000546 -14 146458 12.27 37.5 AS4 AS/MQ0.0000000 NA 11304 11.92 36.3 AS2 DHA+PPQ0.0000000 NA 18589 12.48 36.7 AS4 AS/MQ0.0000000 NA 24304 13.33 36.5 AS4 AS/MQ0.0000000 NA 2272 12.00 37.5 AS2 AS/MQ0.0029401 -8 13605 12.67 38.6 AS2 AS/MQ0.0000000 NA 3956 13.45 36.4 AS2 AS/MQ

Page 48 of 135


Field site

color

TH004-086 197519 Thailand Mae Sot TH4TH004-086 197516 Thailand Mae Sot TH4TH004-087 197333 Thailand Mae Sot TH4TH004-087 197337 Thailand Mae Sot TH4TH004-088 197341 Thailand Mae Sot TH4TH004-088 197522 Thailand Mae Sot TH4TH004-089 197386 Thailand Mae Sot TH4TH004-089 197384 Thailand Mae Sot TH4TH004-090 197545 Thailand Mae Sot TH4TH004-091 197346 Thailand Mae Sot TH4TH004-092 197552 Thailand Mae Sot TH4TH004-093 197369 Thailand Mae Sot TH4TH004-094 197560 Thailand Mae Sot TH4TH004-095 197581 Thailand Mae Sot TH4TH004-096 206945 Thailand Mae Sot TH4TH004-097 206962 Thailand Mae Sot TH4TH004-098 206967 Thailand Mae Sot TH4TH004-099 206982 Thailand Mae Sot TH4TH004-101 206984 Thailand Mae Sot TH4TH004-102 208852 Thailand Mae Sot TH4TH004-103 208858 Thailand Mae Sot TH4TH004-104 208866 Thailand Mae Sot TH4TH004-105 208886 Thailand Mae Sot TH4TH004-106 208912 Thailand Mae Sot TH4TH004-107 208915 Thailand Mae Sot TH4TH004-108 208925 Thailand Mae Sot TH4TH004-110 193135 Thailand Mae Sot TH4TH004-111 211030 Thailand Mae Sot TH4TH004-112 211025 Thailand Mae Sot TH4TH004-113 211019 Thailand Mae Sot TH4TH004-114 211011 Thailand Mae Sot TH4TH004-115 193123 Thailand Mae Sot TH4TH004-116 193130 Thailand Mae Sot TH4TH004-117 210995 Thailand Mae Sot TH4TH004-118 193149 Thailand Mae Sot TH4TH004-120 193154 Thailand Mae Sot TH4TH005-001 205246 Thailand Sisakhet TH5TH005-002 205269 Thailand Sisakhet TH5TH005-003 205290 Thailand Sisakhet TH5TH005-004 205312 Thailand Sisakhet TH5




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 28888 11.75 36.6 AS4 AS/MQ0.0000000 NA 28888 11.75 36.6 AS4 AS/MQ0.0000000 NA 14758 11.95 36.9 AS2 AS/MQ0.0000000 NA 14758 11.95 36.9 AS2 AS/MQ0.0013048 -10 12262 10.67 38.8 AS2 AS/MQ0.0013048 -10 12262 10.67 38.8 AS2 AS/MQ0.0000000 NA 2896 11.27 37.5 AS2 AS/MQ0.0000000 NA 2896 11.27 37.5 AS2 AS/MQ0.0000000 NA 114547 12.00 37.2 AS4 AS/MQ0.0000000 NA 3894 12.00 36 AS4 AS/MQ0.0000000 NA 66191 12.33 38.3 AS4 AS/MQ0.0000000 NA 272740 13.50 38.8 AS2 NA0.0000000 NA 6029 12.83 38.5 AS4 AS/MQ0.0000000 NA 10299 12.17 36.2 AS2 AS/MQ0.0001348 -13 59354 11.75 38.7 AS2 AS/MQ0.0000000 NA 23738 12.78 36.2 AS4 AS/MQ0.0000000 NA 15072 11.97 37.3 AS4 AS/MQ0.0000000 NA 36926 12.25 38 AS4 AS/MQ0.0000000 NA 20912 12.08 38.3 AS2 AS/MQ0.0000000 NA 3344 10.58 36.7 AS2 AS/MQ0.0000000 NA 12058 13.33 37.1 AS2 AS/MQ0.0000000 NA 2700 12.92 36.8 AS4 AS/MQ0.0000000 NA 6971 12.33 37.6 AS2 AS/MQ0.0000000 NA 53443 12.00 37.3 AS4 AS/MQ0.0000000 NA 7159 12.33 36.7 AS4 AS/MQ0.0000000 NA 12246 11.92 37.3 AS2 AS/MQ0.0000000 NA 11053 14.12 37.1 AS2 AS/MQ0.0000000 NA 18463 14.83 38.1 AS2 AS/MQ0.0000000 NA 59346 13.28 37.5 AS4 AS/MQ0.0403842 -5 43978 13.67 38.5 AS4 AS/MQ0.0000000 NA 3136 13.92 36.6 AS2 AS/MQ0.0000000 NA 20096 13.27 39.2 AS4 AS/MQ0.0000000 NA 21101 14.40 37.3 AS4 AS/MQ0.0000000 NA 43332 12.00 37.6 AS2 AS/MQ0.0000000 NA 35796 13.27 40.3 AS2 AS/MQ0.0000000 NA 76742 12.85 38.5 AS4 AS/MQ0.0000000 NA 6406 10.83 37.4 AS4 MQ/PQ0.0000000 NA 12246 21.00 37 AS4 MQ/PQ0.0000000 NA 70838 11.28 37.5 AS4 MQ/PQ0.0000000 NA 6531 11.17 38 AS4 MQ/PQ

Page 49 of 135


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color

TH005-005 205327 Thailand Sisakhet TH5TH005-006 205341 Thailand Sisakhet TH5TH005-007 205374 Thailand Sisakhet TH5TH005-008 205394 Thailand Sisakhet TH5TH005-009 205413 Thailand Sisakhet TH5TH005-010 205441 Thailand Sisakhet TH5TH005-011 205484 Thailand Sisakhet TH5TH005-012 205522 Thailand Sisakhet TH5TH005-013 205507 Thailand Sisakhet TH5TH005-014 205548 Thailand Sisakhet TH5TH005-015 205457 Thailand Sisakhet TH5TH005-017 205595 Thailand Sisakhet TH5TH005-018 232082 Thailand Sisakhet TH5TH005-020 232111 Thailand Sisakhet TH5TH005-021 205606 Thailand Sisakhet TH5TH005-022 232257 Thailand Sisakhet TH5TH005-023 205621 Thailand Sisakhet TH5TH005-024 205715 Thailand Sisakhet TH5TH005-025 232303 Thailand Sisakhet TH5TH005-026 232329 Thailand Sisakhet TH5TH005-027 232360 Thailand Sisakhet TH5TH005-028 232387 Thailand Sisakhet TH5TH005-029 232403 Thailand Sisakhet TH5TH006-002 204865 Thailand Khun Han TH6TH006-003 204875 Thailand Khun Han TH6TH006-004 204900 Thailand Khun Han TH6TH006-006 204935 Thailand Khun Han TH6TH006-007 204951 Thailand Khun Han TH6TH006-009 205020 Thailand Khun Han TH6TH006-010 205024 Thailand Khun Han TH6TH006-011 205038 Thailand Khun Han TH6TH006-012 205052 Thailand Khun Han TH6TH007-001 205750 Thailand Ranong TH7TH007-002 205780 Thailand Ranong TH7TH007-003 205782 Thailand Ranong TH7TH007-004 205798 Thailand Ranong TH7TH007-005 205814 Thailand Ranong TH7TH007-006 205959 Thailand Ranong TH7TH007-007 205981 Thailand Ranong TH7TH007-008 205996 Thailand Ranong TH7




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 20724 13.50 37.1 AS4 MQ/PQ0.0000000 NA 37806 17.42 37.5 AS4 MQ/PQ0.0000000 NA 25120 12.00 38.6 AS4 MQ/PQ0.0000000 NA 66317 17.58 37.5 AS4 MQ/PQ0.0000000 NA 27695 17.00 38.9 AS4 MQ/PQ0.0811881 -4 2365 14.17 36.8 AS4 MQ/PQ0.0000000 NA 96498 14.50 38 AS4 MQ/PQ0.0000000 NA 39564 11.92 37.7 AS4 NA0.0000000 NA 41881 13.50 38.1 AS4 MQ/PQ0.0000000 NA 9137 13.50 37.7 AS4 MQ/PQ0.0000000 NA 37680 12.00 38.7 AS4 MQ/PQ0.0000000 NA 20096 13.50 38.5 AS4 MQ/PQ0.0000000 NA 6406 9.92 37.5 AS4 MQ/PQ0.0000000 NA 5715 9.67 36.2 AS4 MQ/PQ0.0000000 NA 11304 11.00 37.2 AS4 MQ/PQ0.0000000 NA 3956 16.42 38.7 AS4 MQ/PQ0.0000000 NA 5526 17.75 37.7 AS4 MQ/PQ0.0000000 NA 5464 18.83 40 AS4 MQ/PQ0.0000000 NA 37554 12.92 38.2 AS4 MQ/PQ0.0000000 NA 80792 11.92 40 AS4 MQ/PQ0.0000000 NA 20002 14.92 38 AS4 MQ/PQ0.0000000 NA 9546 14.72 38.5 AS4 MQ/PQ0.0000000 NA 5464 16.75 38.3 AS4 MQ/PQ0.0000000 NA 67824 20.00 39 AS4 MQ/PQ0.0000000 NA 14946 14.00 39.4 AS4 MQ/PQ0.0000000 NA 8290 11.00 36.5 AS4 MQ/PQ0.0000000 NA 5526 13.50 37.3 AS4 MQ/PQ0.0000000 NA 13188 16.50 38.5 AS4 MQ/PQ0.0000000 NA 11555 19.00 36.5 AS4 MQ/PQ0.0000000 NA 24618 0.00 37.4 AS4 MQ/PQ0.0000000 NA 16956 22.50 38 AS4 MQ/PQ0.0000000 NA 32 13.50 39.9 AS4 MQ/PQ0.0000000 NA 18903 15.00 39.2 AS2 AS/MQ0.0000000 NA 7536 10.50 38.5 AS4 MQ0.0000000 NA 12560 11.00 37.9 AS2 AS/MQ0.0000000 NA 12309 18.00 37 AS2 AS/MQ0.0000000 NA 20096 15.00 37.5 AS4 MQ0.0000000 NA 40506 10.50 38.5 AS2 AS/MQ0.0000000 NA 6154 12.00 38.3 AS4 MQ0.0000000 NA 13816 13.00 38 AS2 AS/MQ

Page 50 of 135


Field site

color

TH007-009 206020 Thailand Ranong TH7TH007-010 205848 Thailand Ranong TH7TH007-011 205880 Thailand Ranong TH7TH007-012 205901 Thailand Ranong TH7TH007-013 206041 Thailand Ranong TH7TH007-014 206048 Thailand Ranong TH7TH007-015 206084 Thailand Ranong TH7TH007-016 206108 Thailand Ranong TH7TH007-018 206155 Thailand Ranong TH7TH007-019 206176 Thailand Ranong TH7TH007-020 206212 Thailand Ranong TH7TH007-021 206233 Thailand Ranong TH7TH007-023 227923 Thailand Ranong TH7VN001-001 182620 Vietnam Binh Phuoc VNVN001-002 182640 Vietnam Binh Phuoc VNVN001-003 182660 Vietnam Binh Phuoc VNVN001-004 182680 Vietnam Binh Phuoc VNVN001-005 182700 Vietnam Binh Phuoc VNVN001-006 182720 Vietnam Binh Phuoc VNVN001-007 182740 Vietnam Binh Phuoc VNVN001-008 182760 Vietnam Binh Phuoc VNVN001-009 182780 Vietnam Binh Phuoc VNVN001-010 182800 Vietnam Binh Phuoc VNVN001-011 182672 Vietnam Binh Phuoc VNVN001-012 182676 Vietnam Binh Phuoc VNVN001-013 182692 Vietnam Binh Phuoc VNVN001-014 182696 Vietnam Binh Phuoc VNVN001-015 182772 Vietnam Binh Phuoc VNVN001-016 182776 Vietnam Binh Phuoc VNVN001-017 194963 Vietnam Binh Phuoc VNVN001-018 194968 Vietnam Binh Phuoc VNVN001-019 194970 Vietnam Binh Phuoc VNVN001-021 194976 Vietnam Binh Phuoc VNVN001-022 194980 Vietnam Binh Phuoc VNVN001-023 194984 Vietnam Binh Phuoc VNVN001-024 194988 Vietnam Binh Phuoc VNVN001-025 194992 Vietnam Binh Phuoc VNVN001-026 194996 Vietnam Binh Phuoc VNVN001-027 195000 Vietnam Binh Phuoc VNVN001-028 195004 Vietnam Binh Phuoc VN




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 16925 11.00 37.2 AS4 MQ0.0000000 NA 10048 18.50 37.5 AS4 MQ0.0000000 NA 46472 17.00 37.8 AS2 AS/MQ0.0000000 NA 38685 13.00 39.2 AS4 MQ0.0000000 NA 27632 12.50 39.4 AS4 MQ0.0000000 NA 45907 14.00 38.9 AS2 AS/MQ0.0000000 NA 25560 11.50 40.5 AS4 MQ0.0000000 NA 47226 12.50 37.6 AS2 MQ0.0000000 NA 43206 12.00 40 AS4 MQ0.0000000 NA 29390 14.00 40 AS4 MQ0.0000000 NA 40192 12.00 37 AS2 AS/MQ0.0000000 NA 4270 13.00 37.5 AS2 MQ0.0000000 NA 35105 10.50 40.5 AS4 MQ0.0047286 -8 27069 10.75 39.8 AS4 DHA+PPQ0.0000000 NA 37680 15.33 39.4 AS2 DHA+PPQ0.0000000 NA 30144 18.03 38 AS2 DHA+PPQ0.0000000 NA 7913 8.58 37 AS2 DHA+PPQ0.0000000 NA 20661 11.55 37.2 AS4 DHA+PPQ0.0000000 NA 23110 16.82 39.5 AS2 DHA+PPQ0.0000000 NA 11618 19.42 38.4 AS2 DHA+PPQ0.0000000 NA 33410 16.18 37 AS2 DHA+PPQ0.0000000 NA 15449 13.50 40.1 AS4 DHA+PPQ0.0000000 NA 6971 13.97 37 AS4 DHA+PPQ0.0000000 NA 11304 14.50 38.5 AS4 DHA+PPQ0.0000000 NA 14921 10.22 37.9 AS4 DHA+PPQ0.0000000 NA 33912 16.00 37 AS2 DHA+PPQ0.0000000 NA 13188 12.08 37.8 AS2 DHA+PPQ0.0114482 -6 25157 16.00 37.7 AS4 DHA+PPQ0.0000000 NA 33410 11.75 38.2 AS4 DHA+PPQ0.0000000 NA 8792 15.50 39.7 AS2 DHA+PPQ0.0000000 NA 28323 15.33 37.4 AS2 DHA+PPQ0.0000000 NA 7159 17.00 38.9 AS4 DHA+PPQ0.0000000 NA 31086 10.67 39.4 AS4 DHA+PPQ0.0000000 NA 20096 11.75 39.8 AS4 DHA+PPQ0.0000000 NA 25999 15.50 38.6 AS2 DHA+PPQ0.0000000 NA 4522 10.50 38 AS2 DHA+PPQ0.0000000 NA 51308 16.33 36.5 AS4 DHA+PPQ0.0000000 NA 11932 12.08 35.5 AS2 DHA+PPQ0.0000000 NA 25321 11.50 40.2 AS2 NA0.0000000 NA 48042 17.00 38.7 AS2 DHA+PPQ

Page 51 of 135


Field site

color

VN001-029 195012 Vietnam Binh Phuoc VNVN001-030 195016 Vietnam Binh Phuoc VNVN001-031 195008 Vietnam Binh Phuoc VNVN001-032 195020 Vietnam Binh Phuoc VNVN001-033 195024 Vietnam Binh Phuoc VNVN001-034 195028 Vietnam Binh Phuoc VNVN001-035 195032 Vietnam Binh Phuoc VNVN001-036 195036 Vietnam Binh Phuoc VNVN001-037 195040 Vietnam Binh Phuoc VNVN001-038 195044 Vietnam Binh Phuoc VNVN001-039 195048 Vietnam Binh Phuoc VNVN001-040 195052 Vietnam Binh Phuoc VNVN001-041 195056 Vietnam Binh Phuoc VNVN001-042 195060 Vietnam Binh Phuoc VNVN001-045 203929 Vietnam Binh Phuoc VNVN001-046 203933 Vietnam Binh Phuoc VNVN001-047 203937 Vietnam Binh Phuoc VNVN001-048 203941 Vietnam Binh Phuoc VNVN001-049 203946 Vietnam Binh Phuoc VNVN001-050 203948 Vietnam Binh Phuoc VNVN001-051 203953 Vietnam Binh Phuoc VNVN001-052 203957 Vietnam Binh Phuoc VNVN001-053 204061 Vietnam Binh Phuoc VNVN001-054 204097 Vietnam Binh Phuoc VNVN001-055 204065 Vietnam Binh Phuoc VNVN001-056 204069 Vietnam Binh Phuoc VNVN001-057 204073 Vietnam Binh Phuoc VNVN001-058 204077 Vietnam Binh Phuoc VNVN001-059 204081 Vietnam Binh Phuoc VNVN001-060 204085 Vietnam Binh Phuoc VNVN001-061 204089 Vietnam Binh Phuoc VNVN001-062 204092 Vietnam Binh Phuoc VNVN001-063 204101 Vietnam Binh Phuoc VNVN001-064 204105 Vietnam Binh Phuoc VNVN001-066 204113 Vietnam Binh Phuoc VNVN001-067 204117 Vietnam Binh Phuoc VNVN001-068 204121 Vietnam Binh Phuoc VNVN001-069 204125 Vietnam Binh Phuoc VNVN001-070 204129 Vietnam Binh Phuoc VNVN001-072 204057 Vietnam Binh Phuoc VN




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 84780 14.25 37.3 AS2 DHA+PPQ0.0000000 NA 8478 15.00 38.3 AS4 DHA+PPQ0.0000000 NA 24869 20.50 36.6 AS4 DHA+PPQ0.0000000 NA 50868 15.50 36.8 AS4 DHA+PPQ0.0000000 NA 28637 16.58 37.9 AS4 DHA+PPQ0.0000000 NA 8478 12.25 37.4 AS4 DHA+PPQ0.0000000 NA 8541 14.25 38.6 AS2 DHA+PPQ0.0000000 NA 11932 18.08 35.9 AS2 DHA+PPQ0.0000000 NA 69080 12.67 37.8 AS2 DHA+PPQ0.0000000 NA 42704 16.17 38.6 AS4 DHA+PPQ0.0000000 NA 31086 20.17 38.5 AS4 DHA+PPQ0.0000000 NA 14758 12.50 38.1 AS2 DHA+PPQ0.0000000 NA 31651 20.75 37.8 AS2 DHA+PPQ0.0000000 NA 67510 10.50 37.3 AS2 DHA+PPQ0.0000000 NA 49110 14.92 39.1 AS4 DHA+PPQ0.0000000 NA 42202 20.27 37.8 AS2 DHA+PPQ0.0000000 NA 28260 11.75 38.8 AS2 DHA+PPQ0.0000000 NA 24492 14.25 38.7 AS2 DHA+PPQ0.0000000 NA 23738 9.50 39.5 AS4 DHA+PPQ0.0000000 NA 50240 12.50 37.9 AS4 DHA+PPQ0.0000000 NA 81766 17.00 37.9 AS4 DHA+PPQ0.0000000 NA 10299 20.00 38.1 AS4 DHA+PPQ0.0000000 NA 24304 18.50 37.3 AS2 DHA+PPQ0.0000000 NA 69708 10.00 37.5 AS2 DHA+PPQ0.0000000 NA 24021 15.58 36.6 AS4 DHA+PPQ0.0000000 NA 6877 16.58 37.3 AS4 DHA+PPQ0.0000000 NA 91562 0.00 39 AS4 DHA+PPQ0.0000000 NA 8290 11.00 37.7 AS2 DHA+PPQ0.0000000 NA 67259 15.67 37.6 AS4 DHA+PPQ0.0000000 NA 9294 12.00 37.4 AS2 DHA+PPQ0.0000000 NA 10676 18.00 36.3 AS2 DHA+PPQ0.0000000 NA 25560 13.17 39.3 AS2 DHA+PPQ0.0000000 NA 76679 10.17 38.8 AS2 DHA+PPQ0.0000000 NA 48921 13.00 37.8 AS2 DHA+PPQ0.0000000 NA 27758 13.17 37 AS4 DHA+PPQ0.0029652 -8 8094 17.50 38 AS4 DHA+PPQ0.0000000 NA 24304 9.83 35.4 AS4 DHA+PPQ0.0000000 NA 36926 15.42 35.7 AS2 DHA+PPQ0.0000000 NA 54008 20.00 35.9 AS2 DHA+PPQ0.0000000 NA 12560 14.17 34.8 AS4 DHA+PPQ

Page 52 of 135


Field site

color





1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 14318 16.78 36.3 AS2 DHA+PPQ0.0158668 -6 40840 12.75 38.9 AS2 DHA+PPQ0.0000000 NA 13942 17.58 37.8 AS2 DHA+PPQ0.0000000 NA 15826 15.00 37.5 AS4 DHA+PPQ0.0000000 NA 12058 17.25 40.2 AS4 DHA+PPQ0.0000000 NA 54071 18.25 37.1 AS4 DHA+PPQ0.0000000 NA 82645 23.00 38.4 AS4 DHA+PPQ0.0014734 -9 16289 10.25 36.9 AS4 DHA+PPQ0.0000000 NA 10802 10.50 37 AS2 DHA+PPQ0.0000000 NA 7724 19.83 37.2 AS2 DHA+PPQ0.0000000 NA 14758 9.50 38.2 AS4 DHA+PPQ0.0019934 -9 36119 13.75 40.7 AS4 DHA+PPQ0.0000000 NA 11932 10.83 37.1 AS2 DHA+PPQ0.0000000 NA 102615 12.75 40.4 AS2 DHA+PPQ0.0000000 NA 86664 13.67 36.9 AS4 DHA+PPQ0.0000000 NA 19594 11.00 38 AS4 DHA+PPQ0.0000000 NA 52752 12.00 38.3 AS2 DHA+PPQ0.0000000 NA 43960 15.75 38 AS2 DHA+PPQ0.0000000 NA 13188 19.67 37.2 AS2 DHA+PPQ0.0000000 NA 57776 12.00 38 AS2 DHA+PPQ0.0021186 -9 7552 17.17 38.7 AS4 DHA+PPQ0.0000000 NA 5652 10.58 37.8 AS4 DHA+PPQ0.0000000 NA 25120 14.33 38.7 AS4 DHA+PPQ0.0000000 NA 14758 17.25 39.1 AS4 DHA+PPQ0.0000000 NA 11618 9.67 37 AS2 DHA+PPQ0.0000000 NA 58027 12.25 36.6 AS2 DHA+PPQ0.0000000 NA 40192 16.75 40.1 AS4 DHA+PPQ0.0000000 NA 21603 14.50 36.8 AS4 DHA+PPQ0.0000000 NA 79128 15.08 36.7 AS4 DHA+PPQ0.0000000 NA 13502 14.75 38.3 AS2 DHA+PPQ0.0000000 NA 56583 15.75 38.7 AS2 DHA+PPQ0.0000000 NA 9043 8.83 37.1 AS2 DHA+PPQ0.0000000 NA 25120 10.83 38.9 AS4 DHA+PPQ0.0000000 NA 11053 16.75 38.5 AS4 DHA+PPQ0.0000000 NA 35922 18.17 39.1 AS2 DHA+PPQ0.0000000 NA 40192 12.42 41 AS2 DHA+PPQ0.0000000 NA 24492 14.75 40.1 AS4 DHA+PPQ0.0000000 NA 77244 12.25 39.9 AS2 DHA+PPQ0.0000000 NA 50554 16.25 39.6 AS2 DHA+PPQ0.0000000 NA 6594 12.67 38.1 AS4 DHA+PPQ

Page 53 of 135


Field site

color

VN001-115 218627 Vietnam Binh Phuoc VNVN001-116 218631 Vietnam Binh Phuoc VNVN001-117 218635 Vietnam Binh Phuoc VNVN001-118 218639 Vietnam Binh Phuoc VNVN001-119 218643 Vietnam Binh Phuoc VNVN001-120 218647 Vietnam Binh Phuoc VN




1000)


Patient temp. (oC)

ART drug

ACT partner drug

0.0000000 NA 79128 18.08 39.1 AS4 DHA+PPQ0.0000000 NA 4898 9.00 37 AS4 DHA+PPQ0.0000000 NA 20598 12.25 38.5 AS4 DHA+PPQ0.0000000 NA 7159 13.75 37.5 AS2 DHA+PPQ0.0000000 NA 19091 15.00 38.4 AS2 DHA+PPQ0.0000000 NA 58027 19.08 38 AS2 DHA+PPQ

Page 54 of 135


Field site

color



parasite clearance halflife (h)

Tlag (h)

Clearance rate

constant

SE of clearanc

e

Intercept tlag R2 PC50

(h) PC90

(h) PC95

(h) PC99

(h)

4.14 0 0.17 0.03 8.29 0.82 NA 4.71 8.85 18.471.69 0 0.41 0.07 9.43 0.86 0.18 4.09 5.78 9.700.68 0 1.01 0.14 11.07 0.89 1.27 2.86 3.54 5.132.08 0 0.33 0.02 13.18 0.97 4.67 9.51 11.59 16.421.76 0 0.39 0.09 8.91 0.77 NA 3.72 5.48 9.560.87 0 0.80 0.14 8.86 0.89 0.43 2.44 3.31 5.322.45 0 0.28 0.02 11.34 0.98 2.98 8.66 11.11 16.792.71 0 0.26 0.03 10.39 0.88 0.13 6.42 9.14 15.441.37 0 0.50 0.06 11.53 0.92 2.72 5.91 7.28 10.472.37 0 0.29 0.02 11.29 0.98 3.56 9.06 11.42 16.912.20 0 0.32 0.05 9.70 0.85 2.44 7.55 9.75 14.853.19 0 0.22 0.02 10.37 0.93 2.12 9.53 12.73 20.141.91 0 0.36 0.04 11.31 0.92 4.39 8.83 10.75 15.191.29 0 0.54 0.12 9.63 0.87 1.17 4.17 5.46 8.463.37 0 0.21 0.02 10.13 0.95 4.10 11.93 15.30 23.122.76 0 0.25 0.01 11.35 0.98 4.97 11.38 14.14 20.553.44 0 0.20 0.01 12.61 0.98 6.11 14.09 17.52 25.502.88 0 0.24 0.02 9.74 0.96 0.92 7.61 10.49 17.182.23 0 0.31 0.04 9.96 0.92 4.54 9.73 11.96 17.143.21 0 0.22 0.02 9.86 0.95 4.10 11.56 14.77 22.234.44 0 0.16 0.01 10.93 0.97 5.76 16.06 20.50 30.805.43 0 0.13 0.00 10.73 0.99 8.19 20.79 26.22 38.822.53 0 0.27 0.03 10.50 0.91 NA 3.76 6.30 12.181.97 0 0.35 0.05 10.39 0.92 2.56 7.13 9.10 13.671.57 0 0.44 0.05 10.29 0.94 2.49 6.14 7.71 11.353.00 0 0.23 0.02 10.42 0.94 5.33 12.30 15.30 22.272.56 0 0.27 0.02 10.20 0.95 3.54 9.50 12.06 18.022.32 0 0.30 0.04 9.30 0.89 1.26 6.64 8.96 14.353.01 0 0.23 0.01 11.54 0.98 5.72 12.70 15.71 22.703.09 0 0.22 0.02 8.84 0.95 1.43 8.62 11.71 18.892.49 4 0.28 0.01 9.71 0.98 6.23 12.01 14.51 20.291.59 0 0.44 0.04 10.25 0.94 2.10 5.79 7.38 11.061.61 0 0.43 0.04 10.47 0.95 2.21 5.95 7.56 11.293.32 4 0.21 0.01 11.25 0.98 8.99 16.70 20.02 27.744.26 0 0.16 0.01 10.97 0.94 5.34 15.24 19.51 29.413.20 4 0.22 0.01 11.25 0.97 9.23 16.66 19.86 27.292.63 4 0.26 0.01 12.60 0.98 8.79 14.90 17.53 23.64

Page 55 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

3.55 0 0.20 0.01 10.61 0.94 0.23 8.47 12.01 20.252.28 0 0.30 0.02 9.74 0.97 2.66 7.96 10.24 15.544.20 0 0.16 0.01 10.53 0.94 3.59 13.35 17.55 27.311.88 0 0.37 0.06 9.17 0.86 0.40 4.76 6.63 10.992.47 4 0.28 0.01 9.85 0.96 7.77 13.51 15.98 21.711.76 4 0.39 0.01 10.00 1.00 5.25 9.34 11.10 15.192.95 0 0.23 0.01 11.95 0.96 6.96 13.82 16.77 23.622.28 0 0.30 0.04 9.44 0.91 NA 5.13 7.41 12.702.72 0 0.25 0.01 10.78 0.98 4.26 10.57 13.29 19.613.49 0 0.20 0.01 10.12 0.97 6.98 15.09 18.58 26.692.28 4 0.30 0.03 9.33 0.93 6.67 11.97 14.25 19.563.22 0 0.22 0.01 10.88 0.97 6.80 14.27 17.50 24.972.91 0 0.24 0.01 11.43 0.99 5.47 12.22 15.13 21.882.07 0 0.33 0.05 8.61 0.90 NA 4.66 6.73 11.543.23 4 0.21 0.01 11.15 0.98 8.67 16.17 19.40 26.891.59 0 0.44 0.06 9.49 0.89 NA 2.36 3.95 7.642.10 4 0.33 0.02 12.10 0.98 7.58 12.45 14.54 19.421.74 6 0.40 0.02 13.76 0.96 10.90 14.93 16.66 20.692.01 4 0.34 0.03 10.12 0.97 6.53 11.20 13.22 17.901.84 4 0.38 0.03 10.59 0.97 5.83 10.11 11.95 16.241.23 8 0.56 0.14 9.44 0.93 8.76 11.61 12.84 15.701.22 4 0.57 0.03 10.55 0.98 6.14 8.97 10.19 13.021.81 0 0.38 0.04 12.47 0.94 4.02 8.23 10.04 14.241.47 4 0.47 0.02 12.70 0.98 6.35 9.77 11.24 14.661.88 4 0.37 0.01 11.43 0.96 5.90 10.27 12.15 16.522.78 6 0.25 0.01 12.41 0.97 10.28 16.72 19.50 25.952.00 8 0.35 0.02 13.37 0.98 15.10 19.76 21.76 26.421.75 6 0.40 0.01 13.92 0.97 9.27 13.32 15.07 19.120.79 4 0.88 0.10 10.90 0.97 4.63 6.46 7.24 9.072.49 6 0.28 0.01 11.13 0.95 10.27 16.05 18.54 24.322.10 6 0.33 0.01 13.33 0.98 9.89 14.77 16.87 21.742.56 0 0.27 0.02 10.12 0.95 3.57 9.51 12.07 18.021.50 4 0.46 0.06 11.12 0.95 6.59 10.07 11.57 15.062.23 4 0.31 0.01 11.19 0.97 6.93 12.10 14.32 19.492.30 8 0.30 0.02 12.06 0.97 12.06 17.39 19.69 25.032.55 4 0.27 0.01 9.80 0.97 8.17 14.08 16.63 22.54NA 4 0.27 0.01 12.19 0.94 8.00 13.88 16.41 22.30

2.40 0 0.29 0.03 11.73 0.91 4.49 10.07 12.47 18.052.24 0 0.31 0.04 11.92 0.80 5.06 10.26 12.51 17.721.36 4 0.51 0.02 10.09 0.99 5.13 8.30 9.66 12.82

Page 56 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

1.92 4 0.36 0.01 11.42 0.96 7.43 11.90 13.82 18.282.82 6 0.25 0.02 10.49 0.97 9.40 15.95 18.77 25.321.52 4 0.46 0.02 13.09 0.97 7.28 10.82 12.34 15.880.65 0 1.07 0.09 10.20 0.98 0.81 2.33 2.98 4.490.83 0 0.83 0.03 9.25 0.99 0.65 2.58 3.42 5.352.81 0 0.25 0.02 9.39 0.92 1.56 8.09 10.91 17.440.95 6 0.73 0.06 11.60 1.00 6.96 9.17 10.12 12.322.41 0 0.29 0.01 11.54 0.98 4.39 9.99 12.40 18.002.54 0 0.27 0.03 9.35 0.93 NA 5.37 7.91 13.801.59 8 0.44 0.07 12.43 0.95 10.59 14.27 15.85 19.532.28 6 0.30 0.03 10.62 0.96 8.97 14.25 16.53 21.822.57 8 0.27 0.03 10.95 0.92 11.69 17.65 20.22 26.171.88 4 0.37 0.01 10.74 0.99 6.09 10.45 12.33 16.702.04 4 0.34 0.01 11.19 0.99 6.88 11.61 13.64 18.371.44 4 0.48 0.05 10.15 0.93 6.28 9.63 11.06 14.412.20 0 0.32 0.01 10.18 0.99 2.29 7.40 9.60 14.711.24 4 0.56 0.07 10.64 0.93 6.34 9.21 10.45 13.331.34 4 0.52 0.05 11.53 0.98 5.29 8.40 9.74 12.841.89 6 0.37 0.02 12.35 0.97 10.61 15.01 16.90 21.290.76 4 0.92 0.02 10.52 0.98 4.09 5.84 6.60 8.362.00 0 0.35 0.04 11.31 0.90 5.18 9.81 11.81 16.442.50 6 0.28 0.03 10.43 0.94 9.60 15.40 17.90 23.701.68 4 0.41 0.01 10.22 0.94 5.71 9.62 11.30 15.212.39 0 0.29 0.02 10.22 0.97 4.14 9.69 12.08 17.641.97 12 0.35 0.06 10.33 0.93 13.16 17.75 19.72 24.301.45 4 0.48 0.02 12.52 0.95 6.61 9.97 11.41 14.781.74 0 0.40 0.03 11.51 0.95 2.13 6.17 7.91 11.941.60 6 0.43 0.02 11.74 0.94 9.25 12.97 14.57 18.281.71 6 0.40 0.04 10.30 0.94 8.54 12.53 14.24 18.221.70 8 0.41 0.03 12.65 0.97 11.32 15.28 16.98 20.930.73 4 0.95 0.13 11.93 0.96 5.14 6.84 7.57 9.267.00 0 0.10 0.02 9.25 0.69 NA NA 4.88 21.142.47 4 0.28 0.01 11.41 0.98 6.93 12.66 15.13 20.862.40 6 0.29 0.01 13.24 0.97 11.56 17.13 19.52 25.086.26 0 0.11 0.01 8.58 0.83 NA 4.71 10.97 25.502.24 4 0.31 0.01 13.33 0.97 8.72 13.91 16.15 21.342.44 0 0.28 0.03 10.53 0.93 1.67 7.32 9.76 15.411.68 6 0.41 0.04 11.13 0.95 8.46 12.37 14.05 17.951.72 4 0.40 0.01 12.56 0.97 6.62 10.62 12.34 16.352.82 0 0.25 0.02 11.41 0.95 6.55 13.10 15.92 22.46

Page 57 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

3.00 0 0.23 0.01 11.90 0.96 6.10 13.07 16.08 23.052.51 4 0.28 0.02 11.38 0.95 7.41 13.24 15.75 21.584.61 0 0.15 0.01 12.23 0.99 9.27 19.98 24.59 35.312.37 4 0.29 0.02 14.14 0.95 13.14 18.65 21.02 26.522.08 4 0.33 0.01 10.98 0.94 8.00 12.82 14.89 19.711.65 4 0.42 0.01 9.32 0.97 5.40 9.24 10.89 14.731.70 4 0.41 0.02 12.57 0.97 6.79 10.73 12.43 16.382.51 0 0.28 0.02 11.70 0.96 6.07 11.89 14.40 20.221.97 4 0.35 0.02 11.27 0.97 7.25 11.83 13.80 18.382.79 6 0.25 0.02 11.31 0.94 9.90 16.39 19.18 25.671.52 4 0.46 0.02 9.93 0.95 5.45 8.97 10.49 14.014.00 0 0.17 0.03 10.47 0.82 NA 4.13 8.13 17.411.19 0 0.58 0.10 11.67 0.91 1.68 4.45 5.64 8.414.45 0 0.16 0.02 8.45 0.91 NA 7.72 12.17 22.502.01 4 0.34 0.01 11.14 0.96 7.30 11.97 13.98 18.641.61 4 0.43 0.02 13.54 0.97 7.66 11.40 13.01 16.750.99 0 0.70 0.09 10.45 0.92 0.93 3.23 4.22 6.511.93 0 0.36 0.04 8.62 0.94 NA 4.00 5.93 10.421.92 8 0.36 0.02 13.82 0.97 12.75 17.20 19.12 23.571.40 6 0.50 0.03 12.34 0.94 8.43 11.67 13.07 16.311.69 8 0.41 0.05 12.38 0.94 10.64 14.57 16.26 20.191.31 0 0.53 0.10 8.46 0.86 NA 2.28 3.60 6.642.20 6 0.32 0.01 11.94 0.95 10.50 15.60 17.80 22.912.03 4 0.34 0.01 11.65 0.98 7.05 11.75 13.77 18.481.58 4 0.44 0.03 11.88 0.98 7.98 11.64 13.22 16.881.99 0 0.35 0.03 10.39 0.94 0.22 4.84 6.83 11.451.86 6 0.37 0.03 11.29 0.96 9.49 13.82 15.68 20.012.35 0 0.29 0.04 10.22 0.92 1.20 6.67 9.02 14.491.77 4 0.39 0.02 12.02 0.94 7.96 12.06 13.83 17.942.39 6 0.29 0.02 13.31 0.97 10.70 16.25 18.64 24.192.24 0 0.31 0.02 13.28 0.95 5.47 10.67 12.91 18.111.53 0 0.45 0.05 10.18 0.92 NA 2.66 4.18 7.731.72 0 0.40 0.07 9.04 0.86 NA 3.15 4.87 8.861.91 6 0.36 0.03 12.07 0.96 9.02 13.46 15.37 19.812.82 0 0.25 0.02 11.38 0.95 5.51 12.06 14.88 21.432.40 4 0.29 0.01 11.13 0.97 8.49 14.06 16.46 22.032.22 12 0.31 0.03 11.80 0.93 14.45 19.61 21.84 27.001.32 0 0.52 0.06 11.42 0.93 0.96 4.03 5.35 8.421.10 0 0.63 0.12 9.95 0.90 NA 2.19 3.29 5.852.92 0 0.24 0.01 11.39 0.97 5.39 12.16 15.08 21.86

Page 58 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

1.43 0 0.49 0.06 11.14 0.92 2.76 6.08 7.51 10.822.60 8 0.27 0.01 11.82 0.96 12.94 18.97 21.57 27.602.44 0 0.28 0.03 10.18 0.92 NA 5.21 7.65 13.331.44 0 0.48 0.05 10.90 0.93 2.09 5.43 6.87 10.202.34 0 0.30 0.02 11.16 0.96 2.56 8.00 10.34 15.782.66 6 0.26 0.02 11.73 0.94 9.36 15.53 18.19 24.362.75 0 0.25 0.02 11.45 0.96 5.74 12.12 14.87 21.252.39 0 0.29 0.02 13.44 0.96 6.18 11.73 14.12 19.671.82 12 0.38 0.05 13.47 0.96 16.42 20.65 22.47 26.701.63 8 0.43 0.10 10.65 0.96 8.81 12.59 14.22 18.004.26 0 0.16 0.02 10.52 0.90 3.02 12.90 17.16 27.046.27 0 0.11 0.00 11.77 0.98 15.40 29.97 36.24 50.816.21 4 0.11 0.01 12.23 0.95 14.48 28.89 35.10 49.527.06 0 0.10 0.00 12.15 0.99 12.73 29.13 36.20 52.608.70 0 0.08 0.01 12.37 0.94 19.46 39.65 48.35 68.548.37 0 0.08 0.00 9.78 0.98 15.53 34.96 43.32 62.755.57 18 0.12 0.01 13.02 0.95 28.68 41.62 47.20 60.135.48 0 0.13 0.01 11.32 0.92 12.39 25.11 30.60 43.328.34 0 0.08 0.00 11.70 0.96 20.72 40.09 48.44 67.816.04 8 0.11 0.00 12.30 0.93 20.24 34.25 40.29 54.304.69 6 0.15 0.00 11.85 0.99 16.99 27.88 32.56 43.454.51 6 0.15 0.01 10.73 0.96 12.77 23.23 27.74 38.204.17 0 0.17 0.01 11.25 0.95 8.42 18.10 22.27 31.952.37 8 0.29 0.01 12.73 0.93 14.21 19.71 22.08 27.583.19 0 0.22 0.02 10.92 0.94 0.05 7.46 10.65 18.056.31 0 0.11 0.00 12.74 0.97 12.35 27.00 33.31 47.965.80 0 0.12 0.01 10.94 0.96 10.09 23.55 29.35 42.815.41 0 0.13 0.01 11.32 0.97 8.01 20.56 25.97 38.525.81 0 0.12 0.01 11.72 0.98 6.32 19.80 25.60 39.098.38 0 0.08 0.01 11.71 0.91 15.41 34.87 43.25 62.7111.84 0 0.06 0.00 12.31 0.91 19.89 47.38 59.22 86.711.91 6 0.36 0.02 12.85 0.97 9.41 13.85 15.76 20.208.63 12 0.08 0.00 11.27 0.91 24.64 44.67 53.30 73.321.69 4 0.41 0.02 11.73 0.92 6.79 10.72 12.41 16.346.04 0 0.11 0.00 11.34 0.97 9.70 23.73 29.77 43.805.22 4 0.13 0.00 11.06 0.98 10.18 22.30 27.53 39.655.63 0 0.12 0.01 11.84 0.98 7.69 20.75 26.38 39.442.63 6 0.26 0.02 12.02 0.95 9.71 15.82 18.45 24.574.56 4 0.15 0.01 11.49 0.97 9.76 20.35 24.92 35.516.04 0 0.11 0.01 11.03 0.93 9.38 23.40 29.44 43.46

Page 59 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

6.22 0 0.11 0.01 11.94 0.96 12.56 26.99 33.21 47.642.45 4 0.28 0.02 9.49 0.94 5.09 10.78 13.23 18.923.18 8 0.22 0.01 12.65 0.93 13.38 20.75 23.93 31.307.72 0 0.09 0.01 12.53 0.93 15.44 33.36 41.07 58.996.52 0 0.11 0.01 11.59 0.95 9.65 24.78 31.30 46.433.62 0 0.19 0.02 10.34 0.95 5.27 13.67 17.29 25.695.99 8 0.12 0.00 12.32 0.97 18.54 32.44 38.43 52.336.09 0 0.11 0.01 10.73 0.96 2.43 16.57 22.67 36.813.90 8 0.18 0.01 11.02 0.94 14.40 23.47 27.37 36.448.01 0 0.09 0.00 12.46 0.95 18.10 36.69 44.69 63.283.47 0 0.20 0.02 11.59 0.93 6.68 14.73 18.20 26.253.63 6 0.19 0.01 11.02 0.97 11.65 20.08 23.71 32.144.29 0 0.16 0.01 10.60 0.97 6.47 16.42 20.71 30.668.68 0 0.08 0.00 12.31 0.97 22.82 42.98 51.67 71.837.80 0 0.09 0.00 11.57 0.95 15.36 33.47 41.27 59.385.95 0 0.12 0.01 9.91 0.94 NA 13.58 19.53 33.344.02 0 0.17 0.01 11.88 0.97 8.39 17.73 21.75 31.082.36 4 0.29 0.01 11.63 0.97 7.11 12.59 14.95 20.438.34 0 0.08 0.00 11.88 0.96 15.25 34.63 42.97 62.354.60 0 0.15 0.01 10.00 0.96 8.62 19.30 23.90 34.596.84 0 0.10 0.01 12.40 0.96 10.65 26.53 33.37 49.254.62 0 0.15 0.00 9.70 0.99 5.15 15.87 20.49 31.225.21 0 0.13 0.01 11.12 0.95 7.42 19.53 24.74 36.858.36 0 0.08 0.00 12.45 0.96 12.37 31.77 40.12 59.528.68 0 0.08 0.00 11.83 0.94 16.40 36.55 45.23 65.375.42 0 0.13 0.01 10.58 0.97 8.55 21.14 26.57 39.168.30 0 0.08 0.00 9.50 0.98 9.55 28.83 37.13 56.415.04 0 0.14 0.01 11.50 0.98 10.21 21.91 26.95 38.667.66 0 0.09 0.00 10.98 0.98 15.50 33.28 40.94 58.723.92 0 0.18 0.02 9.27 0.90 NA 5.65 9.57 18.685.47 0 0.13 0.00 11.62 0.99 7.30 20.00 25.46 38.164.56 0 0.15 0.01 10.51 0.97 3.17 13.77 18.33 28.935.21 6 0.13 0.00 11.15 0.95 12.27 24.37 29.58 41.686.75 0 0.10 0.00 11.35 0.98 10.64 26.32 33.07 48.755.43 0 0.13 0.00 11.70 0.99 4.82 17.44 22.87 35.4910.02 8 0.07 0.00 11.74 0.93 25.56 48.84 58.86 82.134.89 0 0.14 0.01 12.49 0.98 10.92 22.28 27.17 38.54NA NA NA NA NA NA NA NA NA NA

6.06 0 0.11 0.00 12.45 0.98 10.67 24.75 30.81 44.895.26 0 0.13 0.00 13.80 0.99 14.67 26.89 32.15 44.36

Page 60 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

4.63 12 0.15 0.01 10.51 0.89 16.70 27.46 32.09 42.852.82 4 0.25 0.01 12.43 0.96 8.59 15.14 17.96 24.514.35 0 0.16 0.03 10.28 0.80 NA 9.16 13.51 23.626.36 0 0.11 0.01 9.79 0.94 6.27 21.04 27.41 42.189.97 0 0.07 0.00 11.06 0.90 19.63 42.78 52.74 75.897.28 0 0.10 0.00 12.80 0.98 12.74 29.65 36.93 53.833.33 0 0.21 0.02 12.04 0.96 6.23 13.96 17.29 25.025.81 0 0.12 0.01 9.27 0.96 NA 13.23 19.04 32.544.94 0 0.14 0.01 9.54 0.96 4.34 15.82 20.76 32.246.68 8 0.10 0.00 10.57 0.97 19.87 35.38 42.06 57.576.27 0 0.11 0.01 10.26 0.97 7.91 22.47 28.74 43.307.49 0 0.09 0.00 11.20 0.98 9.88 27.26 34.75 52.137.29 0 0.10 0.00 10.77 0.97 5.33 22.25 29.53 46.466.39 0 0.11 0.01 11.21 0.93 10.31 25.13 31.52 46.352.16 8 0.32 0.03 12.17 0.94 12.96 17.99 20.15 25.184.91 48 0.14 0.01 11.71 0.95 47.91 59.30 64.21 75.607.06 0 0.10 0.00 10.19 0.98 4.22 20.60 27.66 44.041.98 0 0.35 0.04 10.98 0.82 4.49 9.10 11.08 15.697.78 0 0.09 0.01 9.87 0.95 0.17 18.23 26.01 44.076.60 0 0.11 0.01 13.04 0.90 16.36 31.68 38.28 53.606.23 8 0.11 0.01 11.94 0.95 20.90 35.37 41.59 56.065.60 0 0.12 0.01 9.94 0.92 NA 12.67 18.27 31.293.27 4 0.21 0.01 10.95 0.93 8.93 16.51 19.78 27.363.67 0 0.19 0.02 9.06 0.91 NA 7.98 11.65 20.163.87 0 0.18 0.01 10.05 0.99 3.31 12.30 16.18 25.174.41 0 0.16 0.01 11.11 0.99 6.89 17.13 21.54 31.781.97 0 0.35 0.02 11.01 0.97 3.66 8.22 10.19 14.761.89 0 0.37 0.04 10.88 0.93 3.45 7.83 9.72 14.113.58 0 0.19 0.01 9.66 0.97 5.44 13.74 17.31 25.612.89 0 0.24 0.02 10.29 0.95 3.47 10.19 13.08 19.803.49 0 0.20 0.01 11.20 0.95 7.19 15.29 18.78 26.884.83 0 0.14 0.01 10.40 0.97 2.02 13.22 18.05 29.259.04 0 0.08 0.00 10.48 0.97 4.91 25.89 34.93 55.913.28 0 0.21 0.01 11.49 0.98 5.19 12.80 16.08 23.693.38 0 0.20 0.02 10.82 0.91 3.85 11.71 15.09 22.943.01 0 0.23 0.02 11.48 0.92 5.27 12.25 15.26 22.247.43 0 0.09 0.01 9.89 0.90 1.83 19.10 26.53 43.791.77 4 0.39 0.03 10.02 0.96 6.99 11.11 12.88 17.005.53 0 0.13 0.01 11.52 0.96 10.39 23.22 28.75 41.596.46 0 0.11 0.00 11.32 0.97 11.61 26.62 33.09 48.10

Page 61 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

2.91 0 0.24 0.01 11.89 0.96 5.69 12.44 15.35 22.103.64 0 0.19 0.01 12.63 0.96 6.68 15.14 18.78 27.243.86 0 0.18 0.02 11.93 0.87 2.99 11.95 15.81 24.786.68 0 0.10 0.01 11.18 0.95 5.51 21.02 27.69 43.203.82 8 0.18 0.01 12.48 0.93 14.17 23.06 26.88 35.761.50 8 0.46 0.11 10.43 0.93 8.53 12.02 13.52 17.017.44 0 0.09 0.00 10.52 0.97 6.28 23.55 30.99 48.267.51 8 0.09 0.00 12.14 0.94 22.06 39.51 47.02 64.472.71 6 0.26 0.01 12.78 0.92 9.21 15.50 18.21 24.493.38 4 0.21 0.01 11.23 0.97 8.30 16.15 19.53 27.389.16 0 0.08 0.00 11.19 0.94 7.82 29.08 38.24 59.505.27 36 0.13 0.01 10.10 0.90 35.41 47.64 52.91 65.142.84 0 0.24 0.02 12.04 0.94 6.34 12.93 15.77 22.373.24 8 0.21 0.01 11.07 0.97 12.22 19.75 22.99 30.512.35 6 0.29 0.01 11.27 0.97 9.44 14.91 17.26 22.722.20 0 0.31 0.08 9.11 0.79 NA 2.38 4.58 9.702.77 8 0.25 0.02 11.82 0.94 12.24 18.68 21.45 27.892.75 0 0.25 0.02 11.68 0.95 5.78 12.16 14.90 21.285.29 12 0.13 0.00 11.52 0.96 20.34 32.64 37.93 50.237.26 0 0.10 0.01 11.08 0.95 9.22 26.06 33.32 50.162.48 6 0.28 0.01 11.26 0.94 10.96 16.72 19.20 24.964.20 0 0.17 0.01 11.78 0.97 8.72 18.46 22.66 32.402.84 6 0.24 0.01 10.90 0.96 9.82 16.40 19.24 25.824.49 0 0.15 0.01 10.55 0.97 1.83 12.26 16.75 27.172.94 0 0.24 0.02 11.53 0.96 2.89 9.71 12.65 19.489.56 0 0.07 0.00 10.52 0.97 11.34 33.54 43.10 65.311.49 0 0.47 0.09 10.70 0.82 NA 2.12 3.61 7.062.06 4 0.34 0.01 11.20 0.96 7.12 11.90 13.96 18.753.40 0 0.20 0.01 11.98 0.97 7.32 15.23 18.63 26.531.48 0 0.47 0.17 8.95 0.71 NA 1.52 3.00 6.442.66 0 0.26 0.04 9.47 0.81 NA 5.11 7.78 13.962.99 0 0.23 0.02 11.62 0.96 2.70 9.65 12.64 19.583.62 0 0.19 0.02 9.99 0.93 NA 7.08 10.70 19.113.75 0 0.18 0.01 11.15 0.97 6.07 14.78 18.53 27.238.39 0 0.08 0.00 11.17 0.97 13.82 33.31 41.70 61.182.48 0 0.28 0.03 11.17 0.93 4.17 9.93 12.41 18.162.61 6 0.27 0.01 10.91 0.97 9.91 15.98 18.59 24.663.23 0 0.21 0.01 9.77 0.96 2.16 9.66 12.90 20.403.35 0 0.21 0.02 12.04 0.94 6.81 14.59 17.94 25.726.84 8 0.10 0.01 11.57 0.91 14.98 30.85 37.69 53.56

Page 62 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

4.56 0 0.15 0.01 11.55 0.98 5.80 16.39 20.95 31.542.93 0 0.24 0.02 13.14 0.93 7.46 14.26 17.19 23.993.75 0 0.18 0.01 11.14 0.96 3.01 11.71 15.46 24.178.20 0 0.08 0.00 11.09 0.98 8.85 27.89 36.09 55.135.83 0 0.12 0.01 12.08 0.95 10.16 23.70 29.53 43.061.73 4 0.40 0.02 11.46 0.95 7.19 11.20 12.93 16.937.02 0 0.10 0.00 10.52 0.98 0.81 17.09 24.11 40.403.84 0 0.18 0.01 11.69 0.97 5.24 14.14 17.98 26.895.91 0 0.12 0.01 10.13 0.96 6.78 20.50 26.41 40.132.29 0 0.30 0.02 12.06 0.97 4.78 10.10 12.40 17.722.88 0 0.24 0.03 10.44 0.91 1.91 8.59 11.47 18.142.92 4 0.24 0.01 11.55 0.98 7.69 14.47 17.39 24.163.36 0 0.21 0.02 11.58 0.92 6.43 14.22 17.58 25.373.66 8 0.19 0.01 10.91 0.94 13.98 22.49 26.15 34.662.70 0 0.26 0.02 11.72 0.94 4.12 10.38 13.08 19.343.48 0 0.20 0.03 8.32 0.81 NA 4.27 7.75 15.832.62 0 0.26 0.08 8.11 0.70 NA NA 0.99 7.062.70 0 0.26 0.02 11.00 0.94 1.51 7.77 10.47 16.742.27 0 0.31 0.03 11.14 0.92 3.89 9.17 11.44 16.716.88 0 0.10 0.00 9.77 0.98 NA 14.89 21.77 37.752.34 0 0.30 0.03 11.08 0.94 4.04 9.46 11.79 17.2210.03 0 0.07 0.00 10.64 0.95 2.19 25.47 35.50 58.782.89 4 0.24 0.01 10.03 0.97 8.05 14.76 17.65 24.378.53 0 0.08 0.00 11.69 0.99 16.68 36.49 45.01 64.823.71 0 0.19 0.01 10.49 0.98 5.47 14.08 17.79 26.415.48 0 0.13 0.00 12.00 0.97 9.93 22.65 28.13 40.853.07 0 0.23 0.02 11.89 0.95 6.25 13.37 16.44 23.571.84 0 0.38 0.03 11.39 0.97 3.22 7.49 9.33 13.612.37 0 0.29 0.04 10.68 0.84 NA 5.44 7.81 13.323.65 0 0.19 0.01 11.83 0.99 4.20 12.67 16.32 24.793.88 0 0.18 0.01 12.18 0.98 4.91 13.90 17.78 26.782.46 0 0.28 0.02 11.44 0.96 4.75 10.46 12.92 18.622.77 0 0.25 0.01 12.61 0.98 5.96 12.39 15.16 21.584.13 0 0.17 0.01 10.54 0.98 4.04 13.62 17.74 27.325.82 12 0.12 0.01 11.20 0.91 20.36 33.87 39.69 53.211.63 4 0.42 0.02 10.07 0.97 6.48 10.27 11.90 15.707.29 0 0.10 0.00 11.19 0.97 8.69 25.63 32.92 49.854.27 8 0.16 0.01 12.93 0.96 15.64 25.55 29.82 39.732.77 0 0.25 0.02 11.36 0.94 5.20 11.63 14.40 20.833.25 0 0.21 0.02 10.86 0.95 6.90 14.46 17.71 25.27

Page 63 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

6.42 0 0.11 0.00 11.12 0.98 9.56 24.47 30.90 45.812.96 0 0.23 0.01 11.31 0.97 5.39 12.27 15.23 22.104.16 0 0.17 0.01 12.46 0.96 12.03 21.69 25.85 35.513.84 0 0.18 0.01 11.50 0.98 7.48 16.40 20.25 29.171.23 0 0.56 0.09 9.38 0.89 NA 2.30 3.54 6.401.84 4 0.38 0.02 11.06 0.95 7.70 11.97 13.81 18.092.53 4 0.27 0.01 11.00 0.98 7.75 13.61 16.14 22.013.05 0 0.23 0.01 12.55 0.97 6.29 13.38 16.43 23.522.55 0 0.27 0.01 11.54 1.00 3.49 9.41 11.95 17.873.65 0 0.19 0.01 12.08 0.98 5.23 13.71 17.36 25.842.29 4 0.30 0.01 12.17 0.98 7.84 13.15 15.44 20.752.81 4 0.25 0.01 12.17 0.98 8.84 15.35 18.16 24.681.23 4 0.57 0.02 10.22 0.96 5.56 8.41 9.64 12.482.87 0 0.24 0.02 12.92 0.97 4.98 11.65 14.52 21.182.16 12 0.32 0.03 11.42 0.96 14.32 19.35 21.51 26.545.34 0 0.13 0.03 7.74 0.74 NA 3.65 8.99 21.382.36 0 0.29 0.02 11.15 0.96 4.77 10.25 12.61 18.092.92 0 0.24 0.03 13.02 0.89 6.41 13.19 16.11 22.893.03 0 0.23 0.04 8.98 0.81 NA 3.35 6.38 13.422.12 6 0.33 0.01 12.43 0.95 9.18 14.11 16.23 21.162.51 6 0.28 0.01 11.57 0.94 10.85 16.67 19.18 25.001.40 4 0.49 0.02 12.08 0.94 6.88 10.14 11.54 14.802.23 4 0.31 0.02 11.52 0.97 8.30 13.47 15.69 20.861.47 4 0.47 0.03 12.96 0.97 7.27 10.67 12.14 15.542.65 4 0.26 0.01 11.71 0.99 8.48 14.63 17.28 23.441.98 4 0.35 0.01 11.72 0.98 6.99 11.59 13.57 18.161.28 4 0.54 0.08 10.74 0.92 5.20 8.16 9.44 12.413.58 8 0.19 0.01 10.89 0.98 14.03 22.33 25.91 34.211.41 8 0.49 0.12 9.77 0.93 9.66 12.92 14.33 17.591.58 0 0.44 0.05 11.89 0.92 3.14 6.82 8.40 12.081.56 4 0.44 0.03 12.67 0.97 8.43 12.05 13.61 17.232.47 4 0.28 0.01 11.55 0.98 6.16 11.89 14.36 20.092.23 0 0.31 0.02 10.97 0.96 3.96 9.14 11.37 16.551.61 18 0.43 0.09 9.98 0.92 18.27 21.99 23.60 27.321.59 0 0.44 0.12 11.90 -7.26 5.32 9.01 10.60 14.291.53 0 0.45 0.04 11.99 0.95 3.33 6.89 8.42 11.992.71 0 0.26 0.02 10.15 0.96 4.39 10.68 13.39 19.681.12 4 0.62 0.02 10.60 0.93 5.64 8.23 9.35 11.941.16 8 0.60 0.15 9.80 0.91 7.91 10.61 11.77 14.463.13 0 0.22 0.01 12.62 0.98 6.33 13.61 16.74 24.02

Page 64 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

2.16 4 0.32 0.02 12.26 0.94 8.00 13.03 15.20 20.223.75 0 0.18 0.01 12.26 0.96 6.41 15.13 18.88 27.608.57 0 0.08 0.01 9.62 0.85 NA 17.94 26.51 46.413.37 4 0.21 0.01 11.36 0.99 9.67 17.51 20.88 28.723.06 0 0.23 0.02 12.12 0.95 2.82 9.92 12.98 20.082.36 6 0.29 0.01 11.81 0.92 10.10 15.58 17.94 23.423.24 0 0.21 0.02 10.79 0.94 3.09 10.61 13.85 21.383.09 6 0.22 0.01 11.45 0.95 9.14 16.31 19.40 26.572.97 0 0.23 0.02 11.32 0.93 5.02 11.92 14.89 21.793.10 6 0.22 0.01 11.62 0.95 10.17 17.36 20.46 27.653.83 4 0.18 0.01 12.92 0.94 11.91 20.80 24.63 33.520.95 0 0.73 0.09 8.08 0.94 0.35 2.54 3.49 5.695.53 0 0.13 0.00 13.16 0.98 9.58 22.41 27.93 40.764.96 4 0.14 0.00 11.59 0.98 11.89 23.41 28.37 39.893.33 6 0.21 0.01 12.77 0.96 12.03 19.76 23.09 30.823.57 8 0.19 0.01 12.12 0.96 12.49 20.78 24.36 32.652.66 4 0.26 0.01 11.19 0.93 9.06 15.24 17.90 24.093.63 0 0.19 0.02 10.37 0.90 1.79 10.23 13.86 22.301.80 4 0.39 0.01 12.46 0.99 6.68 10.86 12.66 16.842.31 6 0.30 0.01 11.71 0.95 9.15 14.52 16.84 22.203.39 0 0.20 0.01 12.56 0.97 6.00 13.86 17.25 25.113.20 0 0.22 0.01 11.43 0.95 5.35 12.77 15.97 23.402.37 0 0.29 0.03 10.42 0.93 5.38 10.89 13.27 18.781.38 4 0.50 0.02 9.97 0.89 5.66 8.86 10.24 13.443.44 0 0.20 0.01 11.44 0.95 4.56 12.55 15.99 23.972.68 6 0.26 0.01 11.91 0.95 10.43 16.65 19.33 25.552.42 4 0.29 0.02 11.99 0.97 8.07 13.68 16.10 21.713.02 0 0.23 0.01 11.91 0.96 5.32 12.34 15.35 22.372.20 0 0.32 0.06 10.49 0.86 2.84 7.94 10.14 15.243.58 0 0.19 0.01 11.79 0.97 5.10 13.41 16.99 25.303.85 0 0.18 0.01 12.85 0.97 7.76 16.71 20.56 29.513.80 0 0.18 0.01 12.35 0.95 7.58 16.42 20.22 29.053.11 6 0.22 0.01 11.29 0.95 9.99 17.21 20.31 27.534.31 6 0.16 0.01 10.39 0.88 10.69 20.69 25.00 35.005.25 0 0.13 0.01 11.06 0.94 3.85 16.04 21.29 33.482.12 0 0.33 0.03 11.69 0.95 3.57 8.50 10.62 15.554.13 0 0.17 0.02 11.91 0.89 8.90 18.49 22.62 32.202.30 0 0.30 0.04 10.90 0.89 1.84 7.18 9.48 14.823.33 0 0.21 0.01 11.40 0.95 5.23 12.98 16.31 24.052.35 0 0.30 0.04 10.98 0.85 2.39 7.83 10.18 15.62

Page 65 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

3.19 0 0.22 0.03 11.16 0.87 2.91 10.31 13.50 20.903.52 0 0.20 0.02 11.69 0.94 4.15 12.32 15.83 24.002.90 0 0.24 0.04 10.52 0.82 NA 2.89 5.79 12.524.24 0 0.16 0.01 10.21 0.94 5.78 15.63 19.88 29.733.59 6 0.19 0.01 11.38 0.94 10.49 18.84 22.43 30.784.88 8 0.14 0.01 10.83 0.87 13.25 24.58 29.46 40.803.03 0 0.23 0.02 11.21 0.90 5.06 12.10 15.13 22.164.76 0 0.15 0.02 9.55 0.84 0.40 11.46 16.23 27.292.82 0 0.25 0.03 10.10 0.90 2.79 9.34 12.17 18.723.34 0 0.21 0.01 11.11 0.97 5.75 13.52 16.86 24.621.94 4 0.36 0.01 10.62 0.96 5.37 9.86 11.80 16.303.17 0 0.22 0.02 11.79 0.94 5.94 13.29 16.46 23.813.11 0 0.22 0.03 10.61 0.91 4.00 11.21 14.32 21.543.46 0 0.20 0.02 10.74 0.92 NA 7.58 11.05 19.095.04 6 0.14 0.00 11.53 0.96 13.14 24.85 29.89 41.613.20 0 0.22 0.02 11.76 0.93 6.54 13.97 17.18 24.612.29 0 0.30 0.01 11.36 0.99 1.65 6.97 9.27 14.592.55 0 0.27 0.02 10.99 0.94 4.94 10.86 13.41 19.333.03 6 0.23 0.01 11.44 0.95 9.86 16.89 19.92 26.962.86 0 0.24 0.02 12.67 0.95 6.18 12.82 15.68 22.320.67 0 1.04 0.04 9.95 1.00 0.59 2.14 2.80 4.353.45 4 0.20 0.01 11.80 0.97 8.99 17.01 20.46 28.472.64 0 0.26 0.03 11.69 0.92 4.00 10.14 12.78 18.922.53 0 0.27 0.03 10.20 0.90 1.64 7.51 10.03 15.902.84 0 0.24 0.02 10.71 0.93 4.14 10.73 13.57 20.162.51 0 0.28 0.03 11.51 0.91 5.77 11.60 14.12 19.951.92 4 0.36 0.02 10.44 0.96 7.47 11.93 13.85 18.311.98 4 0.35 0.01 10.31 0.94 6.45 11.04 13.02 17.613.38 4 0.21 0.01 11.36 0.94 10.26 18.10 21.48 29.333.33 0 0.21 0.02 10.95 0.96 1.64 9.37 12.70 20.422.94 0 0.24 0.01 11.60 0.97 4.72 11.54 14.48 21.303.26 0 0.21 0.01 11.87 0.96 1.69 9.25 12.51 20.073.95 0 0.18 0.01 10.76 0.92 7.77 16.95 20.91 30.093.99 0 0.17 0.01 10.57 0.96 8.73 17.99 21.98 31.241.48 8 0.47 0.10 9.66 0.93 8.58 12.00 13.48 16.903.00 0 0.23 0.02 11.95 0.95 6.31 13.28 16.28 23.253.72 8 0.19 0.01 11.67 0.94 14.15 22.79 26.51 35.153.66 0 0.19 0.01 11.93 0.96 6.21 14.72 18.38 26.893.09 6 0.22 0.01 11.98 0.95 10.92 18.08 21.17 28.345.99 0 0.12 0.00 12.40 0.99 9.00 22.92 28.91 42.82

Page 66 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

1.71 0 0.40 0.04 13.50 0.95 4.27 8.25 9.97 13.952.91 0 0.24 0.03 10.86 0.90 2.78 9.55 12.46 19.231.24 4 0.56 0.08 9.78 0.88 4.89 7.77 9.01 11.892.48 0 0.28 0.02 11.96 0.92 5.78 11.55 14.03 19.803.01 0 0.23 0.02 12.22 0.94 4.76 11.76 14.77 21.772.45 0 0.28 0.04 10.06 0.84 2.41 8.11 10.56 16.264.48 0 0.15 0.00 11.66 0.99 5.48 15.89 20.37 30.773.69 8 0.19 0.01 11.58 0.95 15.32 23.89 27.59 36.162.23 4 0.31 0.01 10.76 0.95 8.26 13.44 15.67 20.862.32 0 0.30 0.02 11.94 0.95 5.84 11.23 13.55 18.954.57 0 0.15 0.01 10.86 0.95 7.67 18.29 22.87 33.492.31 0 0.30 0.03 10.61 0.95 3.28 8.64 10.94 16.302.48 0 0.28 0.02 11.20 0.94 5.19 10.94 13.41 19.164.71 0 0.15 0.01 10.52 0.97 5.83 16.77 21.48 32.422.23 0 0.31 0.03 10.47 0.93 3.89 9.06 11.29 16.464.37 12 0.16 0.01 11.96 0.98 18.72 28.86 33.23 43.375.42 6 0.13 0.01 10.71 0.92 12.28 24.87 30.29 42.877.20 0 0.10 0.01 10.21 0.95 7.97 24.68 31.88 48.595.46 0 0.13 0.01 12.91 0.94 13.94 26.62 32.08 44.76NA NA NA NA NA NA NA NA NA NA

6.07 0 0.11 0.00 11.18 0.98 9.14 23.24 29.31 43.406.10 0 0.11 0.01 11.10 0.97 10.18 24.34 30.44 44.608.26 0 0.08 0.00 10.32 0.99 8.02 27.20 35.47 54.65NA NA NA NA NA NA NA NA NA NA

3.81 4 0.18 0.01 10.63 0.99 10.12 18.97 22.78 31.645.02 0 0.14 0.01 11.29 0.98 4.09 15.75 20.77 32.437.01 0 0.10 0.00 11.41 0.99 10.38 26.66 33.67 49.965.32 0 0.13 0.01 10.86 0.98 3.01 15.37 20.70 33.065.34 0 0.13 0.00 10.09 0.99 5.39 17.79 23.13 35.524.23 4 0.16 0.01 9.29 0.98 8.66 18.48 22.70 32.523.55 0 0.20 0.01 12.01 0.98 3.93 12.18 15.74 23.995.48 0 0.13 0.01 11.19 0.97 9.59 22.30 27.78 40.504.36 0 0.16 0.01 11.27 0.93 8.41 18.54 22.90 33.045.29 8 0.13 0.00 11.18 0.98 16.78 29.07 34.36 46.656.95 0 0.10 0.00 11.82 0.97 13.69 29.82 36.77 52.893.57 6 0.19 0.01 11.26 0.98 10.60 18.88 22.45 30.737.60 0 0.09 0.00 12.80 0.98 16.77 34.41 42.01 59.667.91 0 0.09 0.00 10.18 0.98 3.56 21.91 29.82 48.186.46 0 0.11 0.01 9.71 0.93 0.39 15.39 21.86 36.865.75 0 0.12 0.00 11.27 0.99 8.30 21.66 27.41 40.76

Page 67 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

3.23 8 0.21 0.02 10.72 0.95 11.79 19.29 22.53 30.035.30 8 0.13 0.00 11.66 0.98 15.35 27.65 32.95 45.257.70 0 0.09 0.01 12.67 0.89 11.67 29.54 37.23 55.107.31 0 0.09 0.00 11.70 0.99 12.74 29.71 37.02 53.996.47 0 0.11 0.00 10.62 0.99 10.32 25.34 31.81 46.827.73 0 0.09 0.00 12.10 0.98 14.80 32.74 40.47 58.411.61 0 0.43 0.06 10.65 0.98 2.82 6.57 8.18 11.932.80 8 0.25 0.01 13.58 0.97 15.57 22.07 24.87 31.375.45 0 0.13 0.01 9.69 0.89 NA 10.05 15.50 28.173.18 0 0.22 0.02 8.84 0.96 1.02 8.40 11.58 18.955.08 12 0.14 0.01 12.11 0.94 19.08 30.87 35.95 47.736.03 0 0.11 0.01 11.14 0.97 6.77 20.77 26.81 40.818.46 0 0.08 0.00 11.43 0.98 13.63 33.27 41.73 61.376.90 0 0.10 0.00 11.14 0.99 7.44 23.46 30.37 46.396.81 4 0.10 0.00 11.31 0.93 13.35 29.17 35.98 51.804.59 0 0.15 0.01 8.02 0.94 3.24 13.91 18.50 29.176.17 0 0.11 0.01 9.48 0.97 4.96 19.28 25.45 39.788.21 0 0.08 0.01 11.65 0.92 13.15 32.21 40.41 59.465.65 0 0.12 0.01 9.94 0.98 7.88 21.01 26.66 39.796.01 8 0.12 0.00 13.68 0.97 21.02 34.98 41.00 54.963.30 4 0.21 0.01 11.72 0.96 8.63 16.30 19.61 27.284.06 0 0.17 0.01 9.42 0.97 3.20 12.63 16.69 26.116.60 0 0.11 0.00 11.62 0.98 9.72 25.05 31.65 46.976.85 0 0.10 0.01 8.41 0.94 NA 13.87 20.72 36.634.76 0 0.15 0.01 12.73 0.98 8.52 19.58 24.34 35.397.60 0 0.09 0.00 10.41 0.96 12.28 29.94 37.54 55.207.94 0 0.09 0.00 10.53 0.99 12.84 31.27 39.20 57.636.89 0 0.10 0.00 11.42 0.99 10.77 26.77 33.66 49.673.67 0 0.19 0.01 11.96 0.98 6.15 14.67 18.33 26.856.29 0 0.11 0.00 10.51 0.99 4.58 19.19 25.48 40.088.90 4 0.08 0.00 10.57 0.95 18.77 39.43 48.33 69.002.92 4 0.24 0.01 11.62 0.96 7.99 14.78 17.70 24.497.18 4 0.10 0.00 12.38 0.97 20.40 37.07 44.25 60.916.99 0 0.10 0.01 8.27 0.92 NA 13.18 20.17 36.407.82 0 0.09 0.00 10.34 0.99 9.88 28.03 35.84 53.996.99 6 0.10 0.00 12.66 0.96 19.70 35.93 42.91 59.143.94 4 0.18 0.01 10.17 0.98 9.44 18.58 22.52 31.663.94 4 0.18 0.01 10.17 0.98 9.44 18.58 22.52 31.667.64 0 0.09 0.00 10.82 0.99 8.47 26.21 33.85 51.596.56 0 0.11 0.00 9.99 0.99 7.02 22.24 28.80 44.03

Page 68 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

4.99 12 0.14 0.00 10.77 0.97 19.20 30.80 35.79 47.393.44 0 0.20 0.01 10.77 0.96 6.22 14.21 17.64 25.626.56 0 0.11 0.01 9.03 0.95 3.99 19.21 25.77 40.998.24 0 0.08 0.00 11.18 0.99 14.51 33.63 41.87 60.997.18 0 0.10 0.00 10.43 0.99 7.63 24.30 31.48 48.154.75 12 0.15 0.01 10.85 0.98 19.39 30.42 35.17 46.207.55 0 0.09 0.01 12.28 0.94 15.04 32.58 40.13 57.676.53 0 0.11 0.00 12.26 0.98 13.34 28.49 35.02 50.188.20 0 0.08 0.00 11.59 0.96 15.37 34.41 42.62 61.668.20 0 0.08 0.00 11.59 0.96 15.37 34.41 42.62 61.666.07 0 0.11 0.00 8.87 0.98 2.45 16.55 22.62 36.726.52 0 0.11 0.00 9.83 0.99 9.44 24.58 31.10 46.236.15 0 0.11 0.00 10.06 0.98 5.08 19.35 25.50 39.777.07 0 0.10 0.00 11.37 0.99 6.98 23.39 30.46 46.867.54 0 0.09 0.00 11.90 0.97 13.76 31.26 38.80 56.314.27 0 0.16 0.04 7.43 0.75 NA 1.51 5.78 15.698.95 0 0.08 0.00 11.92 0.99 13.89 34.68 43.63 64.415.91 0 0.12 0.00 9.73 0.99 6.61 20.33 26.24 39.977.16 0 0.10 0.00 10.22 0.98 7.86 24.48 31.64 48.266.05 0 0.11 0.00 10.29 0.99 2.74 16.78 22.83 36.885.60 0 0.12 0.01 10.90 0.98 8.02 21.03 26.64 39.654.92 4 0.14 0.00 11.45 0.98 10.92 22.35 27.28 38.712.37 6 0.29 0.01 12.15 0.98 10.05 15.57 17.94 23.457.81 0 0.09 0.00 11.04 0.98 8.10 26.23 34.04 52.188.73 0 0.08 0.00 10.79 0.98 13.11 33.37 42.09 62.356.59 4 0.11 0.00 12.06 0.98 14.62 29.94 36.53 51.841.57 0 0.44 0.05 11.43 0.95 2.84 6.49 8.07 11.722.76 0 0.25 0.02 9.33 0.96 2.23 8.63 11.39 17.792.60 0 0.27 0.03 10.18 0.93 3.63 9.66 12.26 18.301.78 4 0.39 0.02 12.06 0.96 7.44 11.56 13.34 17.471.44 0 0.48 0.04 10.44 0.97 0.87 4.22 5.67 9.021.75 0 0.40 0.06 10.36 0.92 2.90 6.96 8.71 12.771.90 0 0.37 0.03 11.31 0.95 3.09 7.50 9.40 13.801.43 13 0.48 0.11 10.57 0.95 13.81 17.14 18.57 21.901.64 0 0.42 0.05 11.65 0.93 2.75 6.56 8.20 12.012.07 4 0.34 0.06 10.13 0.99 6.09 10.88 12.95 17.751.61 6 0.43 0.03 12.24 0.94 8.12 11.86 13.47 17.211.73 0 0.40 0.02 10.43 0.99 1.50 5.51 7.24 11.241.40 0 0.50 0.07 10.20 0.92 1.30 4.55 5.95 9.201.28 0 0.54 0.09 11.53 0.91 2.44 5.40 6.68 9.64

Page 69 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

3.39 0 0.20 0.02 10.06 0.95 5.21 13.09 16.48 24.351.85 0 0.38 0.04 10.68 0.96 3.08 7.37 9.22 13.512.81 0 0.25 0.01 10.01 0.98 2.11 8.63 11.43 17.952.33 0 0.30 0.02 10.03 0.99 2.98 8.39 10.72 16.141.78 6 0.39 0.03 9.97 1.00 7.70 11.83 13.61 17.731.16 6 0.60 0.12 11.58 0.92 7.98 10.66 11.82 14.502.22 6 0.31 0.02 10.97 0.95 10.82 15.98 18.20 23.371.87 7 0.37 0.02 9.45 1.00 8.55 12.89 14.75 19.091.96 0 0.35 0.04 12.95 0.91 4.99 9.55 11.51 16.072.68 0 0.26 0.03 11.11 0.93 5.41 11.65 14.33 20.571.56 6 0.44 0.08 11.57 0.92 8.60 12.22 13.77 17.392.76 0 0.25 0.01 10.21 0.97 1.87 8.27 11.03 17.442.49 12 0.28 0.02 13.73 0.96 19.98 25.76 28.25 34.032.00 0 0.35 0.04 10.93 0.92 3.73 8.38 10.38 15.032.19 0 0.32 0.03 12.21 0.91 5.32 10.41 12.60 17.692.05 6 0.34 0.07 11.48 0.95 8.61 13.36 15.41 20.173.08 0 0.23 0.01 12.44 0.97 6.41 13.55 16.63 23.782.99 0 0.23 0.01 12.15 0.98 6.19 13.14 16.13 23.083.26 6 0.21 0.01 12.28 0.98 12.20 19.76 23.02 30.599.18 0 0.08 0.03 8.95 0.59 NA 6.69 15.87 37.191.09 0 0.64 0.26 10.66 0.86 2.27 4.81 5.90 8.432.17 0 0.32 0.02 12.15 0.97 4.00 9.04 11.21 16.252.05 6 0.34 0.09 11.74 0.41 9.68 14.44 16.49 21.245.60 0 0.12 0.01 11.48 0.84 4.36 17.36 22.95 35.952.95 0 0.23 0.02 11.13 0.96 5.39 12.24 15.19 22.042.68 2 0.26 0.03 11.75 0.94 7.66 13.88 16.56 22.781.18 0 0.59 0.03 11.05 0.99 0.87 3.60 4.78 7.512.35 7 0.29 0.03 10.63 0.97 9.53 14.99 17.34 22.811.32 0 0.52 0.10 11.29 0.85 2.89 5.95 7.28 10.352.99 5 0.23 0.03 10.56 0.99 9.03 15.97 18.96 25.891.43 6 0.48 0.08 10.06 0.92 6.67 10.00 11.43 14.76NA NA NA NA NA NA NA NA NA NA

1.79 0 0.39 0.09 9.66 0.83 NA 2.89 4.68 8.843.29 0 0.21 0.02 12.20 0.93 6.95 14.60 17.89 25.531.51 16 0.46 NA 11.10 -1.12 16.18 19.67 21.18 24.671.68 18 0.41 NA 10.84 -0.11 18.30 22.20 23.88 27.781.26 5 0.55 0.13 11.42 0.81 7.54 10.47 11.73 14.663.17 0 0.22 0.06 13.36 -0.69 9.80 17.16 20.33 27.702.28 18 0.30 0.09 12.26 -0.62 20.48 25.77 28.04 33.322.28 6 0.30 0.04 12.05 0.96 10.56 15.85 18.12 23.41

Page 70 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

2.52 4 0.28 0.03 12.08 0.96 10.07 15.92 18.43 24.281.48 11 0.47 NA 10.52 -4.49 12.92 16.36 17.84 21.281.11 3 0.62 0.17 12.05 0.84 5.04 7.62 8.74 11.331.15 0 0.60 0.38 9.27 0.71 NA 1.24 2.39 5.071.75 6 0.40 0.08 10.03 0.86 8.72 12.78 14.53 18.601.98 6 0.35 0.05 10.31 0.98 7.44 12.03 14.01 18.601.86 0 0.37 0.04 11.38 0.92 2.79 7.11 8.97 13.302.27 7 0.31 0.04 12.18 0.92 11.40 16.66 18.93 24.191.63 12 0.43 0.11 11.65 0.95 13.56 17.34 18.97 22.751.99 12 0.35 0.10 9.82 0.89 13.39 18.01 19.99 24.613.50 0 0.20 0.02 9.97 0.90 5.95 14.08 17.58 25.712.50 0 0.28 0.06 13.12 0.11 7.29 13.09 15.58 21.391.16 7 0.60 0.11 10.55 0.86 8.35 11.05 12.21 14.911.37 0 0.51 0.07 10.87 0.91 2.57 5.76 7.13 10.325.37 0 0.13 0.02 10.83 0.88 NA 8.57 13.94 26.422.02 6 0.34 0.08 10.92 0.86 10.07 14.75 16.76 21.442.25 7 0.31 0.07 11.11 -0.26 10.43 15.65 17.91 23.141.52 0 0.46 0.07 11.00 0.87 3.13 6.66 8.18 11.715.20 0 0.13 0.00 9.33 1.00 6.03 18.10 23.29 35.364.47 0 0.15 0.01 12.60 0.96 9.80 20.18 24.66 35.051.47 12 0.47 0.13 10.99 0.89 13.73 17.15 18.62 22.041.44 0 0.48 0.07 12.38 0.90 1.83 5.16 6.60 9.941.12 0 0.62 0.34 10.74 0.77 2.69 5.29 6.41 9.011.84 6 0.38 0.07 11.92 0.47 7.43 11.71 13.56 17.842.11 7 0.33 0.03 10.65 0.95 8.30 13.21 15.33 20.241.20 0 0.58 0.12 10.43 0.87 2.56 5.36 6.56 9.362.81 0 0.25 0.03 9.50 0.90 2.11 8.64 11.44 17.961.39 12 0.50 0.11 11.69 0.92 14.50 17.72 19.10 22.322.08 0 0.33 0.05 11.35 0.84 4.58 9.40 11.48 16.311.64 7 0.42 0.08 11.29 0.98 9.67 13.46 15.10 18.901.67 7 0.41 0.07 10.42 0.92 8.87 12.76 14.43 18.322.68 6 0.26 0.03 12.74 0.92 11.13 17.34 20.02 26.242.30 9 0.30 0.05 11.47 0.96 11.60 16.95 19.25 24.602.56 4 0.27 0.01 13.00 0.96 7.96 13.90 16.46 22.397.97 0 0.09 0.01 11.93 0.90 6.32 24.83 32.80 51.314.10 0 0.17 0.01 13.20 0.98 5.61 15.13 19.23 28.743.92 0 0.17 0.01 12.18 0.97 4.28 13.90 18.04 27.652.84 12 0.24 0.03 12.04 0.90 17.75 24.35 27.19 33.802.84 12 0.24 0.03 12.04 0.90 17.75 24.35 27.19 33.803.73 0 0.19 0.02 12.31 0.81 9.62 18.27 21.99 30.64

Page 71 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

3.73 0 0.19 0.02 12.31 0.81 9.62 18.27 21.99 30.641.72 0 0.38 0.03 12.44 0.94 4.23 8.50 10.33 14.591.82 4 0.38 0.01 12.60 0.98 6.37 10.60 12.42 16.653.76 0 0.17 0.02 10.16 0.85 1.76 11.28 15.38 24.916.22 0 0.11 0.01 10.83 0.95 1.96 16.41 22.63 37.092.96 0 0.23 0.02 12.21 0.93 3.88 10.77 13.73 20.624.20 0 0.17 0.01 10.63 0.98 7.00 16.76 20.96 30.712.91 0 0.24 0.01 11.22 0.97 4.83 11.58 14.48 21.233.76 6 0.18 0.01 11.70 0.97 12.30 21.02 24.78 33.513.02 8 0.23 0.01 12.98 0.93 14.29 21.30 24.32 31.322.60 0 0.27 0.02 11.28 0.96 3.54 9.58 12.19 18.243.25 6 0.21 0.02 10.64 0.96 10.53 18.06 21.31 28.844.09 0 0.17 0.01 11.15 0.94 4.84 14.34 18.44 27.942.54 12 0.27 0.04 12.06 0.95 15.28 21.17 23.71 29.602.06 4 0.34 0.01 12.76 0.97 7.40 12.19 14.25 19.047.44 0 0.09 0.01 12.08 0.94 12.68 29.94 37.38 54.655.04 0 0.14 0.01 12.21 0.97 9.04 20.75 25.79 37.505.71 0 0.12 0.01 11.65 0.98 0.92 14.19 19.90 33.172.62 12 0.26 0.02 12.61 0.94 15.89 21.96 24.58 30.653.12 8 0.22 0.02 12.69 0.93 13.52 20.75 23.87 31.102.69 0 0.26 0.01 12.85 0.98 6.66 12.90 15.59 21.831.32 0 0.52 0.04 10.56 0.97 0.92 4.00 5.32 8.401.52 4 0.46 0.05 10.31 0.97 6.47 10.00 11.52 15.062.38 0 0.29 0.03 12.04 0.91 5.36 10.90 13.28 18.822.30 6 0.30 0.01 11.42 0.93 10.62 15.97 18.27 23.612.47 0 0.28 0.04 9.38 0.87 NA 5.61 8.08 13.803.28 8 0.21 0.02 11.27 0.96 14.35 21.97 25.26 32.881.97 0 0.35 0.03 10.81 0.95 2.87 7.45 9.43 14.012.64 0 0.26 0.02 10.99 0.95 5.91 12.05 14.69 20.833.11 0 0.22 0.01 9.81 0.96 5.15 12.37 15.48 22.700.75 12 0.92 NA 10.14 1.00 11.38 13.12 13.87 15.612.83 12 0.24 0.03 12.13 0.98 20.49 27.07 29.90 36.483.39 0 0.20 0.02 11.19 0.92 3.55 11.41 14.80 22.661.38 4 0.50 0.03 11.70 0.97 5.72 8.93 10.31 13.523.47 0 0.20 0.02 10.89 0.82 3.94 11.99 15.46 23.516.77 0 0.10 0.01 11.35 0.96 7.54 23.26 30.03 45.752.37 0 0.29 0.03 12.18 0.82 6.21 11.72 14.09 19.602.94 0 0.24 0.03 9.97 0.87 3.67 10.51 13.45 20.292.33 0 0.30 0.02 10.15 0.97 2.96 8.37 10.70 16.122.92 0 0.24 0.02 12.93 0.94 7.20 13.99 16.91 23.70

Page 72 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

2.45 0 0.28 0.04 10.38 0.64 5.91 11.60 14.04 19.733.32 0 0.21 0.01 11.44 0.95 6.17 13.87 17.19 24.904.54 0 0.15 0.01 10.59 0.93 6.28 16.82 21.35 31.892.98 8 0.23 0.01 13.14 0.95 15.36 22.28 25.26 32.183.26 0 0.21 0.01 13.19 0.94 7.66 15.23 18.50 26.083.02 0 0.23 0.01 10.62 0.98 4.48 11.48 14.50 21.504.65 0 0.15 0.01 12.15 0.98 5.13 15.92 20.57 31.366.79 0 0.10 0.01 11.43 0.92 6.29 22.06 28.85 44.623.49 12 0.20 0.04 9.44 0.92 15.82 23.92 27.40 35.503.00 0 0.23 0.03 10.86 0.72 6.36 13.32 16.31 23.274.81 0 0.14 0.01 9.39 0.98 4.36 15.52 20.33 31.503.69 0 0.19 0.01 9.92 0.97 5.30 13.86 17.55 26.114.15 0 0.17 0.01 11.34 0.97 5.78 15.42 19.58 29.222.74 0 0.25 0.03 10.58 0.87 6.39 12.76 15.50 21.872.55 0 0.27 0.03 9.71 0.93 2.37 8.29 10.84 16.762.93 0 0.24 0.01 12.47 0.96 4.12 10.93 13.86 20.674.32 0 0.16 0.01 11.47 0.97 7.08 17.11 21.44 31.478.58 4 0.08 0.00 11.26 0.93 14.32 34.24 42.82 62.752.23 4 0.31 0.03 11.15 0.95 6.68 11.86 14.09 19.281.48 4 0.47 0.04 10.98 0.96 7.34 10.78 12.26 15.713.20 0 0.22 0.02 10.87 0.86 6.28 13.71 16.91 24.341.28 12 0.54 0.13 11.33 0.95 12.81 15.78 17.06 20.032.25 0 0.31 0.02 9.52 0.95 2.80 8.03 10.29 15.527.37 0 0.09 0.01 10.60 0.95 0.71 17.83 25.21 42.333.42 6 0.20 0.02 10.25 0.96 10.41 18.36 21.79 29.733.81 0 0.18 0.01 12.85 0.97 8.42 17.26 21.06 29.904.13 8 0.17 0.01 12.17 0.96 14.09 23.67 27.80 37.373.71 0 0.19 0.02 9.68 0.90 NA 6.90 10.61 19.247.96 0 0.09 0.00 9.83 0.97 4.29 22.77 30.73 49.208.35 0 0.08 0.00 11.41 0.98 11.28 30.67 39.03 58.423.47 0 0.20 0.02 10.82 0.96 0.42 8.48 11.95 20.002.56 6 0.27 0.02 12.15 0.99 11.46 17.39 19.95 25.883.89 0 0.18 0.01 11.01 0.97 1.41 10.45 14.35 23.394.75 0 0.15 0.01 9.81 0.96 8.40 19.42 24.17 35.192.28 0 0.30 0.04 9.35 0.93 NA 4.75 7.03 12.322.67 0 0.26 0.04 8.52 0.85 NA 2.36 5.03 11.218.34 0 0.08 0.00 10.21 0.96 7.07 26.44 34.79 54.165.73 0 0.12 0.01 10.88 0.98 7.63 20.94 26.67 39.982.31 0 0.30 0.02 11.26 0.96 4.27 9.62 11.92 17.287.80 0 0.09 0.01 9.94 0.96 6.43 24.55 32.35 50.47

Page 73 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

5.95 0 0.12 0.00 9.97 0.99 7.02 20.85 26.80 40.638.34 0 0.08 0.00 10.52 0.94 NA 18.03 26.36 45.720.73 0 0.95 0.01 9.10 1.00 0.71 2.41 3.14 4.854.77 0 0.15 0.01 11.07 0.96 5.52 16.59 21.35 32.423.83 0 0.18 0.01 13.69 0.95 10.47 19.36 23.19 32.086.62 0 0.10 0.01 9.57 0.94 NA 12.75 19.36 34.733.18 0 0.22 0.01 12.28 0.95 3.76 11.15 14.33 21.724.91 0 0.14 0.01 9.83 0.95 5.90 17.30 22.22 33.625.61 0 0.12 0.00 12.06 0.99 7.46 20.48 26.09 39.123.00 8 0.23 0.01 13.31 0.98 13.66 20.63 23.63 30.604.68 0 0.15 0.01 9.38 0.93 5.47 16.35 21.03 31.901.45 0 0.48 0.04 7.98 0.97 1.73 5.09 6.54 9.896.67 0 0.10 0.00 10.78 0.98 4.07 19.56 26.23 41.732.70 6 0.26 0.01 9.91 0.96 11.39 17.66 20.36 26.632.45 6 0.28 0.01 12.76 0.98 12.55 18.24 20.70 26.395.46 0 0.13 0.01 11.30 0.93 13.57 26.25 31.70 44.385.76 0 0.12 0.01 11.45 0.93 9.42 22.79 28.55 41.927.64 0 0.09 0.01 9.52 0.91 12.44 30.19 37.84 55.587.67 0 0.09 0.00 13.19 0.98 18.98 36.78 44.45 62.254.52 4 0.15 0.00 10.89 0.92 7.84 18.34 22.86 33.372.26 8 0.31 0.01 12.10 0.98 12.86 18.11 20.37 25.623.12 0 0.22 0.02 9.20 0.96 NA 5.66 8.78 16.034.22 0 0.16 0.02 9.54 0.90 7.01 16.81 21.03 30.834.22 0 0.16 0.02 9.54 0.90 7.01 16.81 21.03 30.838.41 0 0.08 0.01 11.21 0.93 14.11 33.65 42.06 61.608.41 0 0.08 0.01 11.21 0.93 14.11 33.65 42.06 61.602.93 0 0.24 0.04 9.08 0.88 0.42 7.23 10.16 16.972.29 6 0.30 0.02 9.88 0.90 10.31 15.63 17.91 23.225.05 0 0.14 0.01 9.29 0.97 2.19 13.90 18.95 30.672.84 0 0.24 0.04 9.12 0.83 3.64 10.23 13.07 19.657.01 0 0.10 0.00 9.85 0.98 8.82 25.10 32.11 48.396.19 0 0.11 0.01 9.85 0.92 NA 14.18 20.38 34.767.30 0 0.09 0.00 10.04 0.97 0.64 17.60 24.90 41.854.45 0 0.16 0.02 10.52 0.93 5.59 15.92 20.37 30.704.30 0 0.16 0.01 12.44 0.97 9.56 19.54 23.84 33.824.60 0 0.15 0.00 11.20 0.99 2.47 13.14 17.74 28.415.97 0 0.12 0.01 11.27 0.94 11.55 25.41 31.38 45.244.60 8 0.15 0.01 9.34 0.91 12.97 23.65 28.24 38.924.38 0 0.16 0.01 10.52 0.96 1.70 11.87 16.25 26.435.88 0 0.12 0.01 10.34 0.98 6.97 20.61 26.49 40.13

Page 74 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

3.89 0 0.18 0.01 9.79 0.98 1.11 10.15 14.04 23.074.49 4 0.15 0.00 11.53 0.99 13.58 23.99 28.48 38.895.47 12 0.13 0.00 10.55 0.96 21.76 34.46 39.93 52.622.39 0 0.29 0.03 10.27 0.96 4.07 9.63 12.02 17.587.12 0 0.10 0.00 13.04 0.97 15.38 31.92 39.04 55.574.33 0 0.16 0.02 8.92 0.87 NA 6.31 10.64 20.694.55 0 0.15 0.01 11.43 0.98 9.40 19.96 24.51 35.089.13 0 0.08 0.01 10.92 0.87 18.54 39.73 48.86 70.054.44 4 0.16 0.01 9.33 0.99 10.40 20.71 25.15 35.464.26 0 0.16 0.01 10.41 0.99 4.15 14.03 18.29 28.176.18 0 0.11 0.00 10.99 0.98 4.67 19.02 25.20 39.568.85 0 0.08 0.00 12.43 0.96 19.39 39.94 48.79 69.334.99 8 0.14 0.00 11.80 0.95 14.48 26.06 31.05 42.634.15 0 0.17 0.01 10.78 0.98 5.76 15.40 19.56 29.206.03 0 0.11 0.01 8.55 0.97 9.18 23.19 29.22 43.242.75 0 0.25 0.01 12.26 0.97 5.63 12.02 14.77 21.165.32 0 0.13 0.01 11.90 0.96 10.13 22.49 27.81 40.164.59 0 0.15 0.01 9.76 0.96 3.03 13.69 18.28 28.9410.06 0 0.07 0.00 10.65 0.98 21.56 44.92 54.98 78.343.08 0 0.22 0.01 12.48 0.97 8.20 15.36 18.44 25.606.17 0 0.11 0.01 10.97 0.97 0.52 14.84 21.00 35.328.15 0 0.09 0.01 9.80 0.96 11.56 30.49 38.64 57.584.42 6 0.16 0.00 11.89 0.96 13.28 23.54 27.96 38.226.02 0 0.12 0.00 11.54 0.99 5.90 19.88 25.90 39.873.34 0 0.21 0.02 10.62 0.96 0.48 8.23 11.57 19.323.54 0 0.20 0.02 10.34 0.93 NA 5.74 9.28 17.492.32 0 0.30 0.02 12.38 0.96 5.66 11.05 13.38 18.770.62 4 1.12 0.14 9.40 0.75 4.04 5.47 6.09 7.524.42 0 0.16 0.01 11.68 0.93 9.77 20.03 24.45 34.715.02 0 0.14 0.01 8.48 0.91 NA 7.48 12.49 24.145.71 0 0.12 0.02 9.78 0.82 0.36 13.62 19.32 32.585.88 4 0.12 0.00 10.05 0.95 12.19 25.83 31.71 45.366.19 0 0.11 0.00 12.01 0.98 7.94 22.32 28.51 42.885.54 0 0.13 0.00 13.29 0.98 11.14 24.00 29.54 42.406.78 0 0.10 0.01 9.95 0.96 5.99 21.72 28.49 44.234.08 0 0.17 0.02 9.66 0.93 NA 8.47 12.55 22.023.87 0 0.18 0.02 9.49 0.91 NA 5.59 9.46 18.431.84 0 0.38 0.07 8.88 0.92 3.05 7.33 9.18 13.46NA 12 0.22 0.02 10.68 0.94 17.39 24.84 28.05 35.50

1.67 4 0.42 0.03 10.16 0.98 8.52 12.39 14.06 17.93

Page 75 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

2.98 4 0.23 0.01 11.42 0.97 8.94 15.87 18.85 25.782.98 4 0.23 0.01 11.42 0.97 8.94 15.87 18.85 25.785.69 0 0.12 0.01 9.48 0.92 NA 12.22 17.91 31.135.69 0 0.12 0.01 9.48 0.92 NA 12.22 17.91 31.134.82 6 0.14 0.01 10.85 0.99 16.01 27.20 32.02 43.214.82 6 0.14 0.01 10.85 0.99 16.01 27.20 32.02 43.216.74 6 0.10 0.01 9.95 0.97 25.21 40.86 47.61 63.266.74 6 0.10 0.01 9.95 0.97 25.21 40.86 47.61 63.266.11 0 0.11 0.00 12.66 0.97 8.89 23.07 29.18 43.374.58 0 0.15 0.02 7.74 0.82 NA 7.12 11.70 22.322.60 6 0.27 0.01 11.97 0.99 9.25 15.27 17.87 23.89NA NA NA NA NA NA NA NA NA NA

7.96 0 0.09 0.00 10.11 0.96 16.16 34.65 42.61 61.106.50 0 0.10 0.01 10.36 0.94 10.73 26.11 32.74 48.125.40 4 0.13 0.00 12.16 0.98 13.10 25.64 31.04 43.577.26 0 0.10 0.01 10.38 0.95 3.16 20.02 27.28 44.146.37 0 0.11 0.00 10.24 0.99 5.71 20.49 26.86 41.642.50 4 0.28 0.01 11.45 0.96 7.35 13.15 15.65 21.444.59 0 0.15 0.01 11.54 0.96 10.58 21.24 25.83 36.491.19 0 0.58 0.06 8.81 0.96 1.19 3.95 5.14 7.906.18 0 0.11 0.01 9.99 0.89 5.26 19.61 25.79 40.138.95 0 0.08 0.01 8.62 0.90 9.31 30.10 39.06 59.853.18 0 0.22 0.01 8.90 0.97 0.25 7.63 10.80 18.182.57 0 0.27 0.01 12.39 0.97 5.59 11.57 14.14 20.127.77 0 0.09 0.00 10.16 0.98 14.42 32.46 40.23 58.278.72 0 0.08 0.00 11.17 0.93 23.03 44.07 53.13 74.177.89 0 0.09 0.00 11.01 0.97 19.32 37.64 45.53 63.856.16 0 0.11 0.00 11.23 0.98 12.53 26.84 33.01 47.328.10 0 0.09 0.00 12.24 0.99 14.55 33.35 41.44 60.243.78 0 0.18 0.01 12.17 0.98 8.31 17.09 20.87 29.654.73 0 0.15 0.01 8.53 0.97 3.24 14.22 18.95 29.936.43 0 0.11 0.01 10.69 0.96 7.21 22.14 28.56 43.497.62 0 0.09 0.00 10.93 0.97 10.66 28.35 35.97 53.666.52 0 0.11 0.01 11.92 0.95 11.67 26.80 33.32 48.465.65 8 0.12 0.00 11.47 0.93 16.06 29.18 34.83 47.943.71 8 0.19 0.01 12.69 0.97 15.73 24.33 28.04 36.653.18 0 0.22 0.02 9.77 0.90 4.63 12.01 15.19 22.564.87 12 0.14 0.01 10.26 0.88 17.98 29.29 34.15 45.467.48 0 0.09 0.01 12.79 0.88 17.53 34.90 42.38 59.767.55 0 0.09 0.00 9.58 0.98 8.70 26.23 33.78 51.31

Page 76 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

8.52 0 0.08 0.00 10.74 0.98 9.91 29.70 38.23 58.024.82 36 0.14 0.01 10.23 0.91 33.81 45.00 49.81 61.003.84 6 0.18 0.01 11.02 0.94 10.90 19.82 23.66 32.596.16 8 0.11 0.00 12.29 0.97 18.53 32.83 38.99 53.285.32 0 0.13 0.02 11.23 0.88 7.67 20.01 25.33 37.672.70 0 0.26 0.08 6.73 0.58 NA 2.54 5.24 11.517.24 6 0.10 0.00 12.41 0.97 15.75 32.56 39.80 56.606.10 0 0.11 0.01 11.40 0.90 7.17 21.33 27.43 41.5810.86 0 0.06 0.01 12.21 0.90 24.53 49.74 60.59 85.809.34 0 0.07 0.00 9.25 0.96 1.70 23.40 32.74 54.447.03 0 0.10 0.00 11.91 0.97 13.89 30.20 37.23 53.558.85 0 0.08 0.00 10.27 0.98 4.57 25.12 33.96 54.518.63 0 0.08 0.00 9.03 0.98 3.34 23.39 32.03 52.0710.35 0 0.07 0.01 8.65 0.88 NA 24.02 34.37 58.429.88 0 0.07 0.00 10.21 0.98 12.46 35.40 45.28 68.2112.02 0 0.06 0.00 9.48 0.94 11.89 39.79 51.80 79.7012.95 0 0.05 0.00 9.43 0.94 15.12 45.19 58.13 88.2013.91 0 0.05 0.00 8.31 0.93 NA 26.34 40.25 72.534.31 0 0.16 0.01 11.52 0.95 6.15 16.16 20.47 30.487.05 4 0.10 0.00 12.82 0.98 19.49 35.87 42.92 59.294.34 6 0.16 0.01 10.78 0.97 11.47 21.54 25.89 35.963.13 0 0.22 0.03 9.76 0.89 2.68 9.95 13.09 20.363.91 0 0.18 0.02 8.67 0.88 0.34 9.43 13.35 22.445.27 0 0.13 0.01 12.63 0.84 11.48 23.72 28.99 41.236.85 0 0.10 0.01 10.40 0.96 7.80 23.71 30.56 46.471.57 0 0.44 0.09 9.88 0.80 1.93 5.57 7.13 10.774.26 0 0.16 0.02 9.22 0.87 3.72 13.61 17.87 27.763.37 0 0.21 0.01 10.03 1.00 2.65 10.47 13.84 21.665.80 6 0.12 0.00 10.47 0.97 15.30 28.76 34.55 48.027.10 0 0.10 0.01 10.02 0.96 NA 15.56 22.66 39.156.95 0 0.10 0.01 10.15 0.98 4.09 20.22 27.17 43.31NA NA NA NA NA NA NA NA NA NA

5.79 0 0.12 0.01 11.08 0.97 10.30 23.75 29.54 42.994.52 12 0.15 0.01 9.95 0.93 18.64 29.13 33.64 44.134.48 12 0.15 0.01 10.59 0.93 19.42 29.83 34.31 44.725.56 8 0.12 0.00 10.03 0.90 12.95 25.86 31.42 44.346.36 0 0.11 0.00 11.07 0.97 10.66 25.43 31.79 46.562.74 4 0.25 0.01 11.49 0.94 7.49 13.85 16.59 22.957.20 0 0.10 0.01 9.53 0.96 8.36 25.07 32.27 48.995.35 0 0.13 0.01 10.22 0.94 5.28 17.71 23.07 35.50

Page 77 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

5.07 8 0.14 0.00 10.73 0.92 15.24 27.00 32.07 43.834.69 4 0.15 0.00 9.84 0.94 8.21 19.10 23.79 34.696.29 0 0.11 0.00 11.94 0.98 10.86 25.47 31.77 46.383.45 8 0.20 0.01 11.51 0.93 12.74 20.76 24.22 32.247.15 0 0.10 0.01 10.68 0.94 4.67 21.26 28.41 45.006.26 0 0.11 0.01 11.88 0.94 10.38 24.91 31.17 45.693.25 6 0.21 0.01 11.17 0.97 10.81 18.35 21.60 29.152.36 0 0.29 0.03 11.69 0.94 3.15 8.62 10.97 16.449.48 0 0.07 0.01 11.78 0.85 15.15 37.16 46.63 68.643.13 0 0.22 0.02 11.04 0.94 3.40 10.67 13.80 21.073.50 0 0.20 0.01 11.63 0.95 5.20 13.32 16.82 24.945.16 0 0.13 0.01 8.78 0.98 3.13 15.12 20.28 32.278.64 0 0.08 0.00 11.83 0.96 16.96 37.02 45.66 65.725.65 8 0.12 0.00 11.52 0.98 18.78 31.90 37.55 50.671.46 0 0.47 0.04 11.18 0.92 1.35 4.74 6.20 9.591.35 4 0.52 0.04 11.47 0.95 6.24 9.36 10.71 13.835.16 0 0.13 0.01 8.88 0.94 NA 11.28 16.44 28.414.28 0 0.16 0.01 10.98 0.97 6.45 16.40 20.69 30.641.26 4 0.55 0.02 10.59 0.99 4.98 7.90 9.16 12.087.76 0 0.09 0.00 10.05 0.99 7.75 25.76 33.51 51.521.89 4 0.37 0.02 11.80 0.94 7.79 12.18 14.07 18.462.46 6 0.28 0.01 10.69 0.98 9.70 15.40 17.86 23.566.05 0 0.11 0.01 9.80 0.96 8.27 22.31 28.36 42.403.08 0 0.23 0.01 10.66 0.96 5.91 13.06 16.14 23.297.50 0 0.09 0.00 11.94 0.96 19.71 37.12 44.62 62.048.50 0 0.08 0.01 9.87 0.92 NA 12.87 21.38 41.123.50 8 0.20 0.02 10.25 0.92 11.88 20.00 23.50 31.631.42 0 0.49 0.06 11.23 0.95 2.27 5.57 6.99 10.292.67 6 0.26 0.02 11.27 0.96 9.29 15.50 18.17 24.383.92 0 0.18 0.02 8.81 0.92 NA 7.55 11.47 20.582.79 4 0.25 0.01 11.02 0.98 7.09 13.56 16.35 22.832.42 0 0.29 0.01 9.44 0.99 1.99 7.61 10.04 15.662.36 0 0.29 0.03 11.50 0.94 3.94 9.43 11.79 17.286.70 12 0.10 0.00 10.86 0.95 21.16 36.72 43.43 58.991.74 0 0.40 0.04 11.61 0.93 3.63 7.67 9.41 13.458.81 0 0.08 0.01 9.19 0.94 3.33 23.78 32.59 53.051.81 4 0.38 0.02 12.18 0.94 7.49 11.70 13.51 17.716.14 4 0.11 0.00 10.18 0.97 11.02 25.27 31.41 45.67NA NA NA NA NA NA NA NA NA NA

7.26 0 0.10 0.00 12.08 0.97 13.67 30.53 37.80 54.67

Page 78 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

3.46 0 0.20 0.01 12.68 0.96 6.66 14.70 18.16 26.212.73 0 0.25 0.02 9.80 0.97 2.98 9.32 12.05 18.385.17 0 0.13 0.02 9.43 0.87 NA 6.88 12.05 24.054.93 6 0.14 0.00 11.94 0.97 13.87 25.32 30.25 41.694.56 0 0.15 0.01 11.13 0.96 5.71 16.30 20.86 31.457.35 0 0.09 0.00 10.13 0.96 11.46 28.52 35.87 52.933.11 12 0.22 0.01 10.75 0.95 19.63 26.85 29.96 37.183.36 0 0.21 0.02 10.52 0.93 5.50 13.30 16.65 24.458.26 0 0.08 0.00 12.23 0.99 12.99 32.17 40.43 59.614.03 0 0.17 0.01 11.69 0.97 6.00 15.35 19.38 28.744.49 0 0.15 0.01 10.94 0.92 3.84 14.27 18.77 29.203.24 4 0.21 0.01 10.42 0.97 7.83 15.35 18.59 26.112.40 0 0.29 0.03 12.44 0.93 5.43 11.00 13.40 18.985.30 0 0.13 0.01 11.76 0.95 4.87 17.16 22.46 34.761.77 6 0.39 0.03 12.41 0.94 10.11 14.23 16.00 20.126.62 4 0.10 0.00 11.19 0.96 9.13 24.50 31.12 46.495.38 0 0.13 0.01 11.42 0.94 9.07 21.56 26.94 39.432.48 8 0.28 0.03 11.23 0.90 12.01 17.78 20.26 26.022.29 4 0.30 0.01 11.02 0.90 7.11 12.43 14.72 20.032.92 12 0.24 0.02 11.61 0.83 15.29 22.08 25.00 31.786.60 0 0.11 0.00 12.30 0.97 9.39 24.71 31.31 46.631.35 0 0.51 0.08 10.84 0.84 3.13 6.26 7.61 10.756.09 0 0.11 0.00 11.17 0.98 9.46 23.61 29.70 43.852.50 0 0.28 0.03 11.66 0.92 1.82 7.62 10.12 15.937.03 0 0.10 0.01 10.93 0.94 8.51 24.83 31.86 48.198.29 0 0.08 0.01 10.03 0.89 14.30 33.54 41.83 61.084.91 0 0.14 0.01 11.66 0.96 1.63 13.04 17.96 29.376.40 30 0.11 0.01 9.67 0.95 35.97 50.82 57.22 72.071.00 4 0.69 0.04 12.12 0.96 5.46 7.79 8.79 11.136.87 6 0.10 0.00 10.05 0.96 15.02 30.96 37.83 53.781.45 4 0.48 0.02 10.24 0.97 6.03 9.40 10.85 14.226.52 12 0.11 0.00 11.40 0.96 23.82 38.96 45.49 60.642.04 24 0.34 0.04 11.56 0.92 24.92 29.66 31.71 36.451.59 0 0.44 0.05 12.82 0.90 4.63 8.31 9.90 13.582.59 4 0.27 0.02 11.04 0.95 7.01 13.02 15.60 21.611.27 4 0.54 0.05 9.53 0.96 4.97 7.93 9.21 12.163.05 0 0.23 0.02 11.63 0.93 6.76 13.85 16.90 23.998.24 0 0.08 0.01 11.82 0.92 15.48 34.62 42.87 62.016.45 0 0.11 0.00 12.24 0.98 12.53 27.50 33.95 48.913.62 0 0.19 0.01 10.85 0.98 7.37 15.78 19.41 27.82

Page 79 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

2.79 4 0.25 0.01 10.72 0.99 8.65 15.14 17.93 24.422.88 4 0.24 0.01 11.67 0.99 8.44 15.14 18.02 24.721.85 0 0.37 0.03 10.53 0.96 2.65 6.95 8.80 13.112.03 0 0.34 0.04 11.54 0.91 5.50 10.23 12.26 16.992.57 0 0.27 0.02 10.91 0.96 5.61 11.58 14.15 20.131.65 0 0.42 0.04 12.46 0.93 3.70 7.52 9.17 12.993.31 0 0.21 0.02 12.04 0.90 3.41 11.10 14.41 22.105.17 0 0.13 0.01 10.16 0.95 3.43 15.43 20.59 32.591.13 0 0.62 0.05 9.68 0.97 0.63 3.25 4.38 6.991.70 4 0.41 0.06 9.83 0.84 6.15 10.10 11.80 15.750.76 4 0.91 0.03 9.96 0.98 4.40 6.17 6.93 8.711.57 12 0.44 0.06 11.28 0.93 13.78 17.42 18.98 22.623.14 4 0.22 0.01 10.78 0.95 10.32 17.61 20.75 28.042.14 4 0.32 0.01 12.77 0.97 7.79 12.75 14.89 19.857.15 0 0.10 0.00 12.62 0.98 12.88 29.48 36.64 53.251.90 0 0.36 0.04 11.51 0.91 4.47 8.90 10.80 15.222.00 4 0.35 0.01 11.46 0.97 5.69 10.35 12.35 17.013.42 0 0.20 0.01 12.23 0.98 7.59 15.51 18.93 26.868.57 0 0.08 0.00 10.22 0.97 9.06 28.96 37.53 57.424.31 4 0.16 0.00 12.03 0.97 10.60 20.60 24.91 34.911.23 4 0.56 0.03 10.51 0.98 6.81 9.67 10.91 13.772.12 0 0.33 0.03 10.21 0.94 4.79 9.72 11.85 16.788.68 4 0.08 0.00 11.03 0.95 15.31 35.47 44.15 64.321.66 4 0.42 0.02 10.31 0.99 5.69 9.54 11.20 15.054.26 0 0.16 0.01 10.09 0.98 4.49 14.39 18.65 28.554.83 0 0.14 0.02 9.87 0.88 NA 3.53 8.36 19.578.27 0 0.08 0.01 12.11 0.93 18.05 37.25 45.53 64.734.58 0 0.15 0.01 10.64 0.94 4.33 14.96 19.54 30.188.95 0 0.08 0.00 12.59 0.94 16.98 37.75 46.70 67.472.69 0 0.26 0.02 9.93 0.94 1.62 7.86 10.55 16.802.82 0 0.25 0.01 12.15 0.98 4.91 11.46 14.28 20.841.14 4 0.61 0.05 9.60 0.98 4.80 7.44 8.57 11.214.20 0 0.16 0.01 11.58 0.97 8.81 18.57 22.77 32.531.94 0 0.36 0.03 10.77 0.94 4.09 8.59 10.53 15.032.02 4 0.34 0.01 11.45 0.99 6.81 11.51 13.54 18.242.71 8 0.26 0.02 12.13 0.96 13.98 20.26 22.97 29.252.73 8 0.25 0.02 11.76 0.96 14.51 20.84 23.57 29.911.88 4 0.37 0.01 12.44 0.97 7.21 11.58 13.46 17.841.51 6 0.46 0.05 11.63 0.95 7.74 11.23 12.74 16.242.21 0 0.31 0.03 10.19 0.95 4.45 9.58 11.79 16.91

Page 80 of 135


Field site

color



Tlag (h)

Clearance rate

constant

SE of clearanc

e


(h) PC90

(h) PC95

(h) PC99

(h)

5.54 0 0.13 0.00 12.70 0.99 11.39 24.25 29.78 42.641.15 0 0.60 0.10 9.78 0.87 2.12 4.78 5.92 8.587.05 6 0.10 0.00 10.83 0.96 15.15 31.52 38.57 54.934.36 0 0.16 0.01 10.14 0.98 7.93 18.05 22.40 32.523.95 6 0.18 0.01 10.86 0.96 11.69 20.85 24.80 33.963.77 0 0.18 0.01 12.32 0.98 7.33 16.09 19.86 28.62

Page 81 of 135


Field site

color



RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

1.31 20 0.589391 -0.153825 B NA 2 NA3.97 18 0.554082 0.1179614 B NA 1 NA3.61 16 0.598018 0.1327227 B NA 1 NA

11.90 8 0.636242 0.0412851 A 1 NA NA4.06 16 0.402076 0.1582015 B NA 1 NA3.26 18 0.486359 0.1197738 B NA 1 NA3.68 16 0.554886 -0.205466 B NA 1 NA3.35 16 0.621662 0.1694538 B NA 1 NA1.55 16 0.468044 0.0883056 B NA 1 NA7.36 16 0.41633 0.0742987 B NA 1 NA6.18 12 0.543122 -0.189908 B NA 2 NA3.22 10 0.672643 0.3522336 A 2 NA NA1.83 8 0.680823 0.2920927 A 2 NA NA2.08 18 0.440375 -0.240617 B NA 2 NA3.50 8 0.665218 0.4907877 A 2 NA NA5.64 8 0.495804 -0.128842 C NA NA 2

13.69 10 0.663552 0.2752683 B NA 2 NA5.00 14 0.462168 -0.083342 B NA 2 NA3.72 8 0.689344 0.4099306 A 2 NA NA3.01 8 0.674736 0.3309887 A 2 NA NA3.33 10 0.66225 0.3012807 A 2 NA NA5.25 8 0.469629 0.2144645 C NA NA 2

14.00 18 0.56027 0.1193482 B NA 2 NA6.39 14 0.523282 0.2100383 B NA 2 NA

11.26 18 0.455633 0.0259833 B NA 2 NA3.23 8 0.67412 0.2596346 A 2 NA NA

11.93 14 0.370005 0.4162625 C NA NA 14.29 20 0.555999 -0.027448 B NA 2 NA1.85 8 0.69729 0.2901909 A 2 NA NA5.97 18 0.587743 0.1832494 B NA 2 NA4.59 8 0.62207 0.1567385 C NA NA 23.08 18 0.608205 0.1044965 B NA 2 NA4.76 20 0.615002 0.0212126 B NA 2 NA3.42 8 0.663104 0.2357927 A 2 NA NA2.38 8 0.714435 0.328231 A 2 NA NA9.47 14 0.622441 0.1820253 B NA 2 NA7.88 8 0.655472 0.1543378 A 2 NA NA

Page 82 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

10.85 14 0.540027 0.111056 B NA 2 NA3.34 14 0.624856 0.1986784 B NA 2 NA4.25 8 0.631821 0.2163417 A 2 NA NA3.94 18 0.525369 0.2086358 B NA 2 NA3.28 8 0.636667 0.8983857 A 2 NA NA5.47 16 0.593671 -0.195367 B NA 2 NA2.64 8 0.667285 0.3356302 A 2 NA NA3.32 18 0.592314 0.1122493 B NA 2 NA4.14 8 0.648698 0.3613202 A 2 NA NA2.40 8 0.697134 0.3842338 A 2 NA NA0.92 8 0.668168 0.3382361 A 1 NA NA0.74 8 0.669102 0.1006116 A 1 NA NA3.46 8 0.625628 0.5318377 A 2 NA NA1.34 16 0.521621 -0.040999 B NA 2 NA1.03 8 0.606235 0.1023064 A 1 NA NA2.39 16 0.59423 0.3209253 B NA 2 NA3.44 10 0.575821 0.4043659 A 2 NA NA

11.24 8 0.649326 0.2810755 A 2 NA NA21.32 8 0.3458 -0.297133 C NA NA 219.12 12 0.485121 0.2038101 B NA 2 NA6.06 8 0.670305 0.4420926 A 2 NA NA8.85 10 0.619558 0.3008879 B NA 2 NA8.92 14 0.576502 0.3000473 B NA 2 NA5.94 8 0.623032 0.3719112 A 2 NA NA8.63 10 0.560269 0.0748023 B NA 2 NA5.47 12 0.534449 0.0363305 B NA 2 NA4.84 8 0.624638 0.4802719 A 2 NA NA

15.71 8 0.605773 0.4723819 A 2 NA NA5.58 12 0.523077 0.0693297 B NA 2 NA1.56 8 0.629761 0.5384202 A 2 NA NA6.31 8 0.587656 0.4158211 A 2 NA NA2.71 14 0.519871 0.5959451 B NA 2 NA6.00 12 0.421869 -0.077455 C NA NA 2

14.32 8 0.553492 0.2234918 C NA NA 25.51 8 0.619873 0.3887743 A 2 NA NA

27.04 8 0.406224 0.1561798 C NA NA 23.61 8 0.620565 0.3806984 A 2 NA NA5.24 16 0.426883 -0.079435 B NA 2 NA7.86 10 0.534022 0.4319513 B NA 2 NA5.77 16 0.374269 0.0452399 B NA 2 NA

Page 83 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

5.81 8 0.511916 0.1839333 C NA NA 23.67 10 0.614746 0.3107318 A 2 NA NA6.52 8 0.635449 0.4807459 A 2 NA NA3.51 16 0.570599 0.3642932 B NA 2 NA1.30 16 0.52776 0.283311 B NA 2 NA9.31 16 0.544764 0.3837381 B NA 2 NA3.20 8 0.63533 0.516647 A 2 NA NA

10.78 12 0.613223 0.2605795 B NA 2 NA2.66 14 0.553621 0.7155951 B NA 2 NA5.74 8 0.504072 0.5197067 C NA NA 2

11.50 8 0.546297 1.4952286 C NA NA 118.88 8 0.526063 0.1096635 C NA NA 216.13 8 0.526087 0.1029518 C NA NA 25.81 8 0.539847 0.2386084 C NA NA 2

18.30 10 0.496837 0.3225824 C NA NA 22.50 16 0.615252 0.1823661 B NA 2 NA2.58 8 0.667392 0.3405936 A 2 NA NA5.04 10 0.540289 0.3220354 B NA 2 NA5.92 8 0.552703 0.2886674 C NA NA 26.50 14 0.548917 0.3160463 B NA 2 NA1.97 8 0.633495 0.4458999 A 2 NA NA3.90 8 0.466229 0.3054732 C NA NA 24.43 10 0.500096 0.1671872 C NA NA 23.20 10 0.551858 0.4042453 B NA 2 NA

18.89 4 0.481942 0.1760095 C NA NA 27.54 8 0.636327 0.4130902 A 2 NA NA6.25 16 0.514471 0.3114252 B NA 2 NA1.13 8 0.573709 0.5815998 A 2 NA NA1.06 8 0.599579 0.460307 A 2 NA NA6.68 8 0.595228 0.4439776 A 2 NA NA6.46 12 0.585289 0.3713629 B NA 2 NA

15.46 14 0.554975 0.4449093 B NA 2 NA5.22 12 0.585539 0.3870655 B NA 2 NA

17.82 4 0.55998 0.4695092 A 2 NA NA5.69 16 0.458004 0.1265844 B NA 2 NA6.44 8 0.58016 0.5053378 A 2 NA NA2.94 16 0.569622 0.4250536 B NA 2 NA

10.79 10 0.621081 0.713019 A 2 NA NA7.58 8 0.656121 0.4218816 A 2 NA NA3.04 4 0.540022 0.373423 A 2 NA NA

Page 84 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

25.64 14 0.57301 0.448746 B NA 2 NA9.22 16 0.568194 0.2544019 B NA 2 NA3.73 8 0.648325 0.4717083 A 2 NA NA7.58 8 0.643313 0.3375755 A 2 NA NA4.56 8 0.610072 0.462073 A 2 NA NA4.70 8 0.455349 0.0273599 C NA NA 28.91 8 0.640218 0.4579536 A 2 NA NA8.08 10 0.627187 0.2909994 B NA 2 NA2.80 8 0.609641 0.5176246 A 2 NA NA3.21 8 0.639691 0.3528047 A 2 NA NA1.84 10 0.660899 0.2555839 A 2 NA NA

16.55 14 0.511144 0.2768918 B NA 2 NA14.88 16 0.530465 0.3685875 B NA 2 NA3.47 16 0.596677 0.583888 B NA 2 NA2.35 8 0.675067 0.4245811 A 2 NA NA6.88 8 0.631462 0.3309777 A 2 NA NA9.48 16 0.570624 0.2613816 B NA 2 NA4.51 14 0.440286 0.2055744 B NA 1 NA6.17 8 0.53193 0.274922 A 2 NA NA4.72 8 0.595809 0.3502402 A 2 NA NA4.76 8 0.517434 0.3669057 C NA NA 22.60 16 0.615847 0.5401724 B NA 2 NA2.84 8 0.630977 0.5249279 A 2 NA NA2.16 8 0.663511 0.359306 A 2 NA NA2.13 8 0.656897 0.5852373 A 2 NA NA

10.72 14 0.598471 0.2922747 B NA 2 NA1.09 4 0.550939 0.4996148 A 2 NA NA7.91 12 0.56734 0.2876619 B NA 2 NA3.90 8 0.529684 0.327727 C NA NA 23.88 8 0.602176 0.4251851 A 2 NA NA

10.47 8 0.651789 0.4143856 A 2 NA NA3.94 18 0.464845 0.2231169 B NA 2 NA3.49 18 0.615044 0.2553795 B NA 2 NA

10.17 8 0.603899 0.3181088 A 2 NA NA4.42 8 0.675355 0.9321604 A 2 NA NA2.22 8 0.612455 0.3854665 A 2 NA NA6.73 8 0.625262 0.3688411 A 2 NA NA6.01 14 0.504109 -0.404874 B NA 2 NA3.23 16 0.595923 0.2163679 B NA 2 NA

16.23 10 0.612377 0.2381149 B NA 2 NA

Page 85 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

1.08 14 0.641422 0.1702237 B NA 2 NA2.50 12 0.630653 0.3199174 B NA 2 NA2.01 16 0.616889 0.3268711 B NA 2 NA5.30 14 0.624592 0.2833527 B NA 2 NA7.58 16 0.564314 0.2728456 B NA 2 NA8.07 14 0.490549 0.2680365 C NA NA 23.11 10 0.663415 0.3235067 A 2 NA NA5.46 8 0.603797 0.3761872 A 2 NA NA2.63 8 0.609863 0.4659163 A 2 NA NA1.56 8 0.693353 0.3391557 A 2 NA NA3.36 8 0.722371 0.2475068 A 1 NA NA0.96 8 0.663851 0.0650147 A 1 NA NA1.91 8 0.604239 0.2709278 A 1 NA NA2.35 10 0.704298 0.3352334 A 1 NA NA2.90 8 0.628997 0.391297 A 1 NA NA3.84 12 0.42695 0.3564506 C NA NA 15.57 8 0.700925 0.4287874 A 1 NA NA

12.12 12 0.45609 0.2431614 C NA NA 13.09 8 0.731129 0.3438123 A 1 NA NA3.49 10 0.640242 0.3468276 A 1 NA NA3.31 8 0.701263 0.2748358 A 1 NA NA

13.26 8 0.546333 1.7632446 C NA NA 14.41 8 0.713674 0.3816065 A 1 NA NA4.10 8 0.705416 0.5009932 A 1 NA NA9.30 16 0.5597 0.268614 B NA 1 NA1.75 8 0.52306 0.1831174 A 1 NA NA4.04 8 0.718022 0.3385984 A 1 NA NA2.04 8 0.65308 0.3301258 A 1 NA NA9.83 8 0.5909 0.062319 C NA NA 12.56 8 0.730182 0.4553436 A 1 NA NA4.39 8 0.577519 0.2457009 A 1 NA NA0.97 8 0.608034 0.2812089 A 1 NA NA2.22 8 0.683808 0.5967561 A 1 NA NA4.25 8 0.596529 0.3451022 C NA NA 11.51 8 0.702861 1.1033794 A 1 NA NA0.98 10 0.530333 0.2845518 C NA NA 16.70 8 0.661373 0.2082397 A 1 NA NA1.47 8 0.693164 0.4411571 A 1 NA NA1.26 8 0.681237 0.4806119 A 1 NA NA1.04 12 0.242397 0.4051858 C NA NA 1

Page 86 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

2.18 10 0.548883 0.2227058 C NA NA 13.62 16 0.565289 0.0505981 B NA 1 NA3.82 8 0.685765 0.3944279 A 1 NA NA3.21 8 0.686191 0.4508352 A 1 NA NA3.02 8 0.660598 0.2978112 C NA NA 12.76 10 0.583139 0.2167102 C NA NA 11.07 8 0.708075 0.4190726 A 1 NA NA2.82 16 0.612768 0.3450625 B NA 1 NA3.26 10 0.634097 1.2454595 B NA 1 NA4.98 8 0.668954 0.4192464 A 1 NA NA3.87 12 0.591469 0.6239433 B NA 1 NA5.02 10 0.562878 0.246095 C NA NA 15.78 8 0.534018 2.0338133 C NA NA 13.64 4 0.57979 0.363293 A 1 NA NA4.06 8 0.692826 0.2975333 A 1 NA NA3.38 4 0.438418 -0.049788 C NA NA 17.40 4 0.57161 0.3485854 A 1 NA NA7.85 8 0.724095 0.3345969 A 1 NA NA2.50 8 0.640119 0.2915514 A 1 NA NA2.12 12 0.488661 0.3207158 B NA 1 NA7.16 8 0.729805 0.25942 A 1 NA NA4.38 10 0.625192 0.1955119 B NA 1 NA1.74 8 0.62069 0.1096939 C NA NA 13.81 8 0.669761 0.185982 A 1 NA NA1.59 8 0.71674 0.172445 A 1 NA NA1.59 12 0.665725 0.0939141 B NA 1 NA1.05 8 0.541178 0.4598252 C NA NA 15.80 8 0.704699 0.1979061 A 1 NA NA2.02 10 0.473227 0.2470357 C NA NA 14.34 8 0.473747 -0.072582 C NA NA 11.19 8 0.710123 0.1980571 A 1 NA NA2.52 14 0.584665 0.1553654 B NA 1 NA8.90 8 0.613509 0.2389538 A 1 NA NA2.55 12 0.670727 0.1535109 B NA 1 NA6.17 10 0.65948 0.2281568 B NA 1 NA3.63 8 0.680523 0.5595291 A 1 NA NA1.36 8 0.619963 0.3764466 A 1 NA NA6.04 8 0.670531 0.2863474 A 1 NA NA1.01 10 0.647964 0.1861055 C NA NA 1

11.71 8 0.715486 0.2174653 A 1 NA NA

Page 87 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

5.76 14 0.605791 0.0562976 B NA 1 NA3.72 8 0.694217 0.3859006 A 1 NA NA6.07 14 0.289702 0.2536581 C NA NA 12.54 8 0.625912 0.1879167 C NA NA 12.55 8 0.708939 0.2820875 A 1 NA NA6.35 8 0.684263 0.3460222 A 1 NA NA4.26 8 0.713511 0.4643978 A 1 NA NA5.18 8 0.640936 0.1533617 C NA NA 11.73 14 0.271515 0.5356518 C NA NA 13.32 8 0.423791 0.4201686 C NA NA 13.98 14 0.652375 0.3418531 B NA 1 NA3.56 8 0.712707 0.275489 A 1 NA NA4.61 10 0.681093 0.6677923 A 1 NA NA4.86 8 0.713274 0.2046399 A 1 NA NA4.98 8 0.65352 0.1149454 C NA NA 1

10.74 10 0.629027 0.1870145 C NA NA 13.28 14 0.626623 0.5760087 B NA 1 NA3.90 8 0.6406 0.1967599 C NA NA 17.72 8 0.684832 1.1304959 C NA NA 14.15 8 0.648873 0.1405352 A 1 NA NA4.19 8 0.722888 0.318959 A 1 NA NA4.66 8 0.640607 0.3459103 C NA NA 1

14.40 10 0.560199 0.6037328 C NA NA 12.90 8 0.380143 0.4163865 C NA NA 12.80 16 0.602245 0.660394 B NA 1 NA4.49 8 0.720622 0.7442074 A 1 NA NA4.11 8 0.562828 -0.141369 C NA NA 11.38 10 0.659844 0.0802631 B NA 1 NA3.38 8 0.526853 0.3644407 C NA NA 12.80 8 0.570949 0.314596 C NA NA 14.84 4 0.434777 0.3649562 C NA NA 12.34 14 0.608621 -0.11762 B NA 1 NA5.27 4 0.444972 1.8296885 C NA NA 13.27 14 0.597481 0.1122742 B NA 1 NA1.43 8 0.567418 0.1175009 C NA NA 12.89 8 0.691546 0.2403673 A 1 NA NA3.03 8 0.638438 -0.049353 A 1 NA NA1.35 8 0.617129 0.1941824 C NA NA 12.92 12 0.661834 -0.043497 B NA 1 NA1.79 8 0.531875 0.125505 C NA NA 1

Page 88 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

4.91 8 0.649825 0.2045022 C NA NA 19.43 8 0.662652 0.2799799 A 1 NA NA7.61 8 0.68548 0.1024519 A 1 NA NA4.00 8 0.707983 0.3083743 A 1 NA NA7.10 8 0.700408 0.2848444 A 1 NA NA3.51 8 0.672182 0.1465864 A 1 NA NA2.84 8 0.62868 0.0253102 C NA NA 13.81 8 0.723978 0.3838008 A 1 NA NA

12.04 8 0.656547 0.4735396 A 1 NA NA7.67 8 0.590466 -0.037651 A 1 NA NA6.27 8 0.657471 0.3268952 A 1 NA NA2.42 10 0.697552 0.1306146 A 1 NA NA

10.10 8 0.579921 0.3294297 A 1 NA NA3.86 8 0.658318 0.4250859 A 1 NA NA2.91 8 0.650638 0.2828107 A 1 NA NA5.24 16 0.558969 0.1075299 B NA 1 NA

12.39 8 0.674474 0.3499672 A 1 NA NA2.85 8 0.723814 0.2309658 A 1 NA NA3.25 10 0.636442 0.3336474 B NA 1 NA0.82 8 0.701492 0.3184474 A 1 NA NA6.66 8 0.669134 0.0095998 A 1 NA NA

10.43 4 0.521918 0.0981891 C NA NA 14.56 8 0.598675 0.4173878 A 1 NA NA3.35 8 0.728334 0.2896399 A 1 NA NA4.84 14 0.66829 0.2287111 B NA 1 NA

15.02 8 0.661758 0.246455 C NA NA 111.31 16 0.588937 0.2095205 B NA 1 NA1.60 8 0.514763 0.1402992 C NA NA 12.70 4 0.620026 0.4970843 A 1 NA NA2.93 14 0.493105 0.3550726 B NA 1 NA

13.87 12 0.515556 0.7403414 B NA 1 NA12.06 8 0.715953 0.5578891 A 1 NA NA5.34 8 0.631165 0.3597052 A 1 NA NA

13.60 16 0.595243 0.0741457 B NA 1 NA4.35 8 0.669618 0.2746132 A 1 NA NA4.93 8 0.650169 0.0856127 A 1 NA NA4.91 8 0.694168 0.153401 A 1 NA NA2.62 8 0.69625 0.3908776 A 1 NA NA4.78 8 0.655819 0.5070606 A 1 NA NA4.92 8 0.7126 0.4328517 A 1 NA NA

Page 89 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

5.02 8 0.58049 0.188628 A 1 NA NA4.23 8 0.625824 0.3603527 A 1 NA NA4.12 8 0.697144 0.295486 A 1 NA NA4.27 8 0.701522 0.0549874 A 1 NA NA7.76 8 0.692418 0.4228862 A 1 NA NA4.42 8 0.624966 0.2596339 A 1 NA NA9.28 14 0.578762 0.1547893 B NA 1 NA4.74 8 0.713645 0.2793611 A 1 NA NA4.50 10 0.541691 -0.062461 B NA 1 NA1.40 8 0.677367 0.322157 A 1 NA NA4.46 10 0.63994 0.1638029 A 1 NA NA8.77 8 0.573251 0.1967278 A 1 NA NA2.03 8 0.701863 0.2171155 A 1 NA NA7.34 12 0.596359 0.1703345 B NA 1 NA6.93 8 0.675076 0.3103419 A 1 NA NA5.80 14 0.569309 0.0111391 B NA 1 NA9.34 16 0.572725 0.1202919 B NA 1 NA8.35 8 0.60543 0.1516538 A 1 NA NA2.15 8 0.669177 0.444875 A 1 NA NA3.55 12 0.541184 0.1455324 B NA 1 NA3.32 8 0.707707 0.2318351 A 1 NA NA9.52 8 0.688303 0.0294475 A 1 NA NA4.89 4 0.537847 0.2328665 C NA NA 13.94 8 0.520261 0.0986144 C NA NA 12.83 12 0.66882 0.1688965 B NA 1 NA3.00 10 0.701979 0.1841916 A 1 NA NA2.66 8 0.537021 0.2165259 C NA NA 14.06 8 0.521845 0.4340464 C NA NA 15.80 14 0.620168 0.3420536 B NA 1 NA4.12 8 0.704651 0.2387873 A 1 NA NA

15.24 8 0.695477 0.4608629 A 1 NA NA1.99 8 0.689647 0.3422113 A 2 NA NA5.55 8 0.635725 0.1306526 A 2 NA NA6.35 10 0.593167 0.371659 B NA 2 NA6.28 8 0.669473 0.3957289 A 2 NA NA0.80 8 0.615956 0.4858455 A 2 NA NA8.18 8 0.624187 0.1284071 A 2 NA NA9.99 8 0.625629 0.3511751 A 2 NA NA1.85 8 0.70811 0.3141616 A 2 NA NA9.33 8 0.652558 0.4065254 A 2 NA NA

Page 90 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

8.47 8 0.684016 0.4125985 A 2 NA NA2.21 8 0.655755 0.4801648 A 2 NA NA6.90 8 0.625746 0.2934474 A 2 NA NA5.87 8 0.531471 -0.067594 A 2 NA NA3.53 14 0.271995 0.3943939 C NA NA 1

37.05 6 0.506313 0.2080068 C NA NA 24.72 8 0.650534 0.3452246 A 2 NA NA6.28 8 0.675575 0.3843782 A 2 NA NA9.45 14 0.598318 0.1510912 B NA 2 NA3.55 10 0.670257 0.3091885 A 2 NA NA

21.90 8 0.661998 0.2963523 A 2 NA NA7.99 8 0.638663 0.4275921 A 2 NA NA4.56 8 0.58387 0.3049043 C NA NA 2

22.46 14 0.620082 0.234125 B NA 2 NA5.51 4 0.505192 0.1834399 A 2 NA NA

12.22 16 0.341033 0.2163484 B NA 2 NA2.17 8 0.662329 0.2896033 A 2 NA NA

15.27 8 0.688221 0.3484208 A 2 NA NA8.78 16 0.602805 0.207447 B NA 2 NA9.10 8 0.690103 0.3276113 A 2 NA NA7.64 8 0.634052 0.3606446 A 2 NA NA

11.79 8 0.679665 0.2680517 A 2 NA NA5.80 8 0.630061 0.3475418 A 2 NA NA

10.09 8 0.684958 0.2869733 A 2 NA NA17.10 8 0.620477 0.4032713 A 2 NA NA8.71 8 0.655526 0.1536006 A 2 NA NA2.79 12 0.637602 0.2453117 B NA 2 NA4.61 8 0.545224 0.2559877 C NA NA 23.03 8 0.62982 0.3078856 A 2 NA NA3.00 8 0.46759 0.1667015 C NA NA 15.68 8 0.621868 0.2697924 A 1 NA NA3.24 8 0.6864 0.3958149 A 1 NA NA4.19 8 0.610593 0.3231948 C NA NA 17.06 8 0.590414 0.3252309 A 1 NA NA4.15 8 0.603488 0.1999483 A 1 NA NA

13.94 12 0.529486 -0.199093 B NA 1 NA3.71 8 0.528786 0.2283616 C NA NA 11.06 16 0.532898 0.1417667 B NA 1 NA4.39 16 0.580664 0.1079604 B NA 1 NA

12.15 8 0.668753 0.3895024 A 1 NA NA

Page 91 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

6.17 8 0.682433 0.3257114 A 1 NA NA6.44 8 0.681183 0.2049723 A 1 NA NA2.60 8 0.702938 0.3976454 A 1 NA NA4.74 8 0.708069 0.3361026 A 1 NA NA5.15 8 0.690375 0.3259942 A 1 NA NA4.54 8 0.695703 0.2313633 A 1 NA NA2.13 16 0.612473 0.1937504 B NA 1 NA5.63 8 0.724754 0.2955932 A 1 NA NA7.01 8 0.665381 0.2019629 A 1 NA NA3.37 8 0.666984 0.2894809 A 1 NA NA8.73 8 0.669468 0.3498645 A 1 NA NA4.03 4 0.117555 0.1664593 C NA NA 14.99 8 0.627834 0.2587242 A 1 NA NA4.18 8 0.588901 0.3465633 A 1 NA NA9.30 8 0.658253 0.1900152 A 1 NA NA5.35 8 0.597262 0.1564974 A 1 NA NA2.31 8 0.654028 0.1608924 A 1 NA NA2.05 16 0.619665 0.2598518 B NA 1 NA8.42 8 0.717851 0.4060275 A 1 NA NA6.40 8 0.642732 0.3752039 A 1 NA NA3.66 8 0.607323 0.3593915 A 1 NA NA1.07 8 0.484657 0.0325776 C NA NA 13.30 8 0.65691 0.237869 A 1 NA NA

11.86 16 0.415355 -0.02936 B NA 1 NA6.16 10 0.662087 0.1932715 A 1 NA NA2.22 8 0.650161 0.4671989 A 1 NA NA4.37 8 0.617642 0.3240518 A 1 NA NA6.80 8 0.660699 0.3154053 A 1 NA NA5.84 12 0.602399 0.2839694 B NA 1 NA9.03 8 0.643864 -0.146018 A 1 NA NA8.20 8 0.622694 0.2079148 A 1 NA NA7.10 8 0.584791 0.025901 C NA NA 16.67 8 0.601393 0.3882447 A 1 NA NA

38.05 12 0.473311 0.72178 C NA NA 114.29 12 0.623239 0.0525365 B NA 1 NA0.90 16 0.634783 0.3066864 B NA 1 NA6.77 8 0.661973 0.0512407 A 1 NA NA4.39 16 0.575595 0.0716403 B NA 1 NA5.39 8 0.69159 0.4445236 A 1 NA NA4.71 8 0.668658 0.2747807 A 1 NA NA

Page 92 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

1.34 8 0.656227 0.3005986 A 1 NA NA4.56 8 0.690321 0.5703701 A 1 NA NA

10.94 18 0.554542 0.0478251 B NA 1 NA4.22 10 0.607075 0.235326 C NA NA 1

26.92 8 0.616217 0.3212903 A 1 NA NA7.14 8 0.672494 0.1225175 A 1 NA NA4.59 8 0.463875 0.1272012 C NA NA 15.06 14 0.468595 0.3509804 B NA 1 NA

13.37 16 0.386794 0.1274572 B NA 1 NA2.80 8 0.607514 0.1653096 A 1 NA NA3.65 8 0.599201 0.083142 A 1 NA NA5.11 8 0.651304 0.4589355 A 1 NA NA3.73 12 0.57252 0.0469643 B NA 1 NA4.28 16 0.564031 0.1665099 B NA 1 NA

16.68 8 0.639298 0.2320719 A 1 NA NA7.97 8 0.599452 0.2200795 A 1 NA NA

16.08 16 0.639161 0.3287303 B NA 1 NA3.43 8 0.625924 0.1580423 C NA NA 17.73 8 0.567757 0.3240221 A 1 NA NA8.31 8 0.681673 0.3629401 A 1 NA NA1.98 16 0.566595 0.2471208 B NA 1 NA5.63 4 0.608663 0.3676681 A 1 NA NA

18.38 8 0.558746 0.1817309 C NA NA 12.40 16 0.533407 0.1862269 B NA 1 NA5.75 14 0.525195 0.2449935 B NA 1 NA5.66 8 0.557528 0.3823982 C NA NA 13.42 8 0.587226 0.3338681 A 1 NA NA1.39 4 0.489864 1.7725845 C NA NA 12.96 8 0.676921 0.3108785 A 1 NA NA1.95 12 0.631675 0.0513687 B NA 1 NA8.40 12 0.570181 0.1501225 B NA 1 NA

17.74 14 0.630299 0.1570878 B NA 1 NA20.04 8 0.586789 0.1615563 C NA NA 12.06 4 0.529341 0.3933588 C NA NA 11.89 16 0.58605 0.2349759 B NA 1 NA4.99 8 0.643052 0.4203313 A 1 NA NA

12.98 46 0.311482 2.2396695 C NA NA 14.66 8 0.65645 0.4415643 A 2 NA NA3.72 8 0.600179 0.467238 A 2 NA NA4.58 8 0.609374 0.3589438 A 2 NA NA

Page 93 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

11.23 10 0.669971 0.3673008 A 2 NA NA8.86 8 0.579224 0.3420947 C NA NA 29.65 16 0.532786 0.1497024 B NA 2 NA8.82 8 0.652159 0.5055607 A 2 NA NA5.82 8 0.647844 0.5071057 A 2 NA NA3.02 8 0.618162 0.3728405 A 2 NA NA4.71 8 0.55373 0.2043488 C NA NA 26.70 4 0.527721 0.2858704 C NA NA 1

10.82 8 0.60485 0.2805422 A 2 NA NA3.60 8 0.638894 0.4642338 A 2 NA NA8.32 10 0.614399 0.2925641 B NA 2 NA5.12 16 0.568348 0.0960509 B NA 2 NA6.60 4 0.470777 0.2936545 C NA NA 2

47.78 6 0.410579 0.1594206 C NA NA 24.69 8 0.54003 0.3093247 C NA NA 21.13 10 0.699068 0.2887112 A 1 NA NA1.72 8 0.68912 0.6176036 A 1 NA NA1.59 8 0.561662 0.2217592 C NA NA 11.15 8 0.704367 0.4057454 A 1 NA NA2.26 8 0.641766 0.7169736 A 1 NA NA1.88 8 0.664096 0.3005472 A 1 NA NA2.09 8 0.646425 0.9749232 A 1 NA NA1.68 8 0.617591 0.2997587 A 1 NA NA0.79 8 0.65623 0.1507923 A 1 NA NA2.24 10 0.634885 0.5006223 B NA 1 NA5.94 8 0.678725 1.4223427 A 1 NA NA2.01 8 0.666746 0.5156194 A 1 NA NA3.34 14 0.654025 0.3503794 B NA 1 NA2.38 10 0.568762 0.5519611 A 1 NA NA2.19 8 0.563244 1.5455409 C NA NA 11.79 16 0.698003 0.39404 B NA 1 NA2.00 8 0.627944 0.8103726 A 1 NA NA4.26 8 0.63916 0.4549595 A 1 NA NA4.44 8 0.603981 0.3697791 A 1 NA NA2.42 8 0.701216 0.4330399 A 1 NA NA2.00 8 0.637909 0.3494072 A 1 NA NA4.10 8 0.681099 0.4467738 A 1 NA NA3.12 8 0.652479 0.482871 A 1 NA NA2.88 10 0.673175 0.7050417 A 1 NA NA1.66 8 0.702751 0.3913083 A 1 NA NA

Page 94 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

10.85 8 0.564387 1.1950746 C NA NA 13.98 8 0.693138 0.4752345 A 1 NA NA2.73 8 0.681594 0.3345018 A 1 NA NA1.45 8 0.628883 0.8530541 A 1 NA NA1.97 8 0.659955 0.8596683 A 1 NA NA3.72 8 0.698252 0.45169 A 1 NA NA4.07 12 0.61068 0.2232144 B NA 1 NA3.42 4 0.590766 0.6739228 A 1 NA NA2.24 14 0.654978 0.3634996 B NA 1 NA2.08 8 0.566145 1.6818298 C NA NA 12.28 8 0.656107 0.5971254 A 1 NA NA2.66 12 0.705838 0.4059263 B NA 1 NA6.62 10 0.658317 0.9181065 A 1 NA NA8.66 8 0.682648 0.545839 A 1 NA NA1.76 10 0.60938 0.6934814 A 1 NA NA4.03 8 0.671617 0.7606352 A 1 NA NA1.82 10 0.563765 0.6512437 C NA NA 13.34 8 0.664407 0.5860263 A 1 NA NA3.31 12 0.386794 0.2183608 C NA NA 14.11 8 0.581118 0.1348428 A 1 NA NA9.84 8 0.692723 1.1839012 A 1 NA NA4.11 14 0.439202 0.3625032 B NA 1 NA4.86 8 0.679848 0.3137603 A 1 NA NA1.40 12 0.385616 0.2730115 C NA NA 16.21 8 0.711121 0.2235601 A 1 NA NA1.93 8 0.570304 0.0908138 C NA NA 11.14 8 0.54611 0.1276916 C NA NA 12.70 14 0.676053 0.0612254 B NA 1 NA5.08 10 0.671502 0.558297 A 1 NA NA1.74 10 0.636699 0.4333033 B NA 1 NA3.35 4 0.636824 0.359521 A 1 NA NA7.46 8 0.617714 1.378656 A 1 NA NA2.78 8 0.626454 0.3616782 A 1 NA NA2.25 14 0.496248 0.3142235 B NA 1 NA3.46 8 0.65837 0.3278666 A 1 NA NA3.61 14 0.615937 0.0754651 B NA 1 NA6.77 8 0.630944 0.300058 C NA NA 17.02 44 0.168569 0.2239643 C NA NA 1

11.79 8 0.677417 0.3913074 A 1 NA NA7.97 10 0.511553 0.2166248 C NA NA 1

Page 95 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

14.15 8 0.484322 0.1403651 C NA NA 110.31 8 0.27848 1.8269949 C NA NA 114.24 4 0.30807 1.52935 C NA NA 13.39 8 0.634688 0.2013635 A 1 NA NA2.02 8 0.69814 0.3695685 A 1 NA NA5.49 8 0.466413 0.2391079 C NA NA 26.00 8 0.623943 0.3275333 A 2 NA NA4.88 8 0.683935 0.2965768 A 2 NA NA

12.90 8 0.651302 0.1436208 A 2 NA NA2.32 10 0.685146 0.3552656 A 2 NA NA5.76 14 0.245096 0.3035497 C NA NA 12.54 10 0.664496 0.4341659 A 2 NA NA6.11 14 0.580678 0.2430972 B NA 2 NA6.92 12 0.638889 0.3021282 B NA 2 NA8.54 8 0.663927 0.2373567 A 2 NA NA3.09 16 0.515238 -0.071361 B NA 2 NA7.04 8 0.643318 0.2832632 A 2 NA NA6.59 8 0.31358 -0.106353 C NA NA 26.51 8 0.677616 0.2781827 A 2 NA NA7.75 8 0.252235 0.2535284 C NA NA 19.48 8 0.645127 0.8550578 A 2 NA NA5.27 8 0.668061 0.3830877 A 2 NA NA

14.81 8 0.639561 0.3747336 A 2 NA NA4.47 8 0.676338 0.4095111 A 2 NA NA4.25 10 0.639036 0.3159916 A 2 NA NA2.03 8 0.638728 0.4106885 A 2 NA NA8.99 8 0.710262 0.2280061 A 1 NA NA2.38 14 0.618036 0.3342583 B NA 1 NA3.86 8 0.710812 0.2721702 A 1 NA NA4.88 8 0.715333 0.8502128 A 1 NA NA2.53 18 0.61006 0.0752869 B NA 1 NA2.76 16 0.662103 0.3046906 B NA 1 NA5.31 14 0.652274 0.244996 B NA 1 NA4.85 8 0.70096 0.4060521 A 1 NA NA5.05 12 0.655604 0.196082 B NA 1 NA6.02 8 0.699052 0.3689322 A 1 NA NA3.29 8 0.690386 0.4506072 A 1 NA NA2.16 16 0.656964 0.2497009 B NA 1 NA1.81 16 0.614352 0.2208655 B NA 1 NA1.92 16 0.65598 0.2925078 B NA 1 NA

Page 96 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

1.22 10 0.553191 0.9329101 A 1 NA NA0.92 8 0.692084 0.0743488 A 1 NA NA1.86 12 0.647307 0.3766464 B NA 1 NA

12.81 8 0.535719 1.9199203 C NA NA 11.26 8 0.732077 0.2629703 A 1 NA NA2.35 8 0.685308 0.2225506 A 1 NA NA1.60 8 0.64513 0.3093814 A 1 NA NA1.42 8 0.628455 0.1731118 C NA NA 11.84 8 0.71742 0.3901941 A 1 NA NA3.37 10 0.656181 0.3157853 B NA 1 NA2.41 8 0.651602 0.2871794 A 1 NA NA8.72 12 0.546589 -0.049651 B NA 1 NA

16.47 4 0.47858 0.178396 A 1 NA NA2.61 8 0.63173 0.1584441 A 1 NA NA5.40 8 0.634206 0.2698639 A 1 NA NA2.34 8 0.669788 0.3558653 A 1 NA NA5.54 8 0.646555 0.0975159 A 1 NA NA9.56 8 0.659286 0.3494728 A 1 NA NA1.83 8 0.616075 0.2792281 A 1 NA NA

17.36 8 0.549637 -0.166555 C NA NA 14.09 14 0.601809 0.0881929 B NA 1 NA3.33 4 0.454173 0.1396226 C NA NA 13.04 8 0.690294 0.3332432 A 1 NA NA5.82 12 0.68123 0.2000422 B NA 1 NA1.78 8 0.639633 0.2024918 C NA NA 12.97 4 0.465129 0.2138901 C NA NA 12.56 16 0.572525 0.1276519 B NA 1 NA3.21 8 0.649583 0.2228317 A 1 NA NA1.56 8 0.645902 0.298338 C NA NA 15.26 4 0.578366 0.3025144 A 1 NA NA2.26 12 0.51728 -0.027253 B NA 1 NA4.94 4 0.410401 0.1091892 C NA NA 14.94 14 0.611316 0.2329152 B NA 1 NA3.91 8 0.644166 0.2883777 A 1 NA NA7.88 4 0.625914 0.265332 A 1 NA NA4.30 4 0.596714 0.2615409 A 1 NA NA3.97 8 0.606534 0.255756 C NA NA 18.76 4 0.458344 0.1551955 C NA NA 16.08 4 0.569221 0.2216081 C NA NA 1

12.43 8 0.609087 0.2970992 A 1 NA NA

Page 97 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

3.05 4 0.427148 0.3021791 C NA NA 13.99 4 0.55945 0.2285763 C NA NA 14.03 8 0.641929 0.3400173 A 1 NA NA3.44 16 0.511152 0.0977203 B NA 1 NA

10.73 8 0.593434 0.2417458 C NA NA 13.23 8 0.54157 0.3397815 C NA NA 13.09 12 0.606539 0.2292749 B NA 1 NA0.84 8 0.681995 0.268986 A 1 NA NA0.78 8 0.642994 0.2976873 A 1 NA NA4.04 8 0.65684 0.3804601 A 1 NA NA2.93 12 0.653458 0.1662365 B NA 1 NA5.92 8 0.686412 0.3474261 A 1 NA NA4.47 8 0.625337 0.3775154 A 1 NA NA6.73 18 0.287611 0.2058206 C NA NA 12.24 8 0.684671 0.3628663 A 1 NA NA

43.37 4 0.523657 -0.006848 C NA NA 118.84 8 0.644685 0.0933983 C NA NA 110.44 8 0.611904 0.0990349 C NA NA 13.71 8 0.58306 0.342321 C NA NA 14.63 8 0.667164 0.4773106 A 1 NA NA8.00 8 0.587031 0.3729175 A 1 NA NA

20.99 14 0.570799 0.4785729 B NA 1 NA2.18 44 0.114299 0.2032961 C NA NA 16.06 16 0.622353 0.2071353 B NA 1 NA2.50 8 0.657311 0.3728585 A 1 NA NA1.66 4 0.119387 0.0966983 C NA NA 11.10 16 0.578941 0.2046226 B NA 1 NA3.68 4 0.522571 0.1850935 C NA NA 12.66 8 0.56253 0.1110952 A 1 NA NA3.66 4 0.5718 0.4436784 C NA NA 15.08 8 0.467757 0.0763104 C NA NA 12.35 4 0.587425 0.4692292 A 1 NA NA4.89 4 0.548015 0.0034723 A 1 NA NA9.19 8 0.709189 0.4054698 A 1 NA NA3.43 8 0.678554 0.2301623 A 1 NA NA8.13 8 0.713299 0.45076 A 1 NA NA6.37 10 0.721922 0.2517815 A 1 NA NA5.21 8 0.714378 0.2504532 A 1 NA NA8.16 8 0.658858 0.3549436 A 1 NA NA3.39 8 0.708477 0.3613475 A 1 NA NA

Page 98 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

7.21 8 0.633884 0.3104069 A 1 NA NA4.79 8 0.697167 0.1346062 A 1 NA NA4.38 8 0.689107 0.3015844 A 1 NA NA0.96 14 0.643044 0.543549 B NA 1 NA3.60 8 0.69202 0.2996232 A 1 NA NA

22.00 8 0.662602 0.3839583 A 1 NA NA20.85 8 0.650744 0.6266881 C NA NA 114.17 8 0.652491 0.3162122 A 2 NA NA14.06 8 0.638464 0.2997859 A 2 NA NA12.61 8 0.671213 0.2435406 A 2 NA NA4.02 10 0.686438 0.3437863 A 2 NA NA6.07 8 0.627317 0.4453087 A 2 NA NA

22.44 8 0.610872 0.1515877 C NA NA 210.58 8 0.658463 0.2019617 A 2 NA NA16.26 10 0.689203 0.1918165 A 2 NA NA6.25 8 0.679248 0.4127481 A 2 NA NA8.28 8 0.641704 0.3012267 A 2 NA NA

17.38 14 0.655393 0.1446707 B NA 2 NA18.49 8 0.616908 0.3659916 A 2 NA NA15.88 46 0.387601 1.5309517 C NA NA 111.96 10 0.68745 0.3649633 A 2 NA NA8.88 16 0.529199 -0.134598 B NA 2 NA5.93 8 0.640453 0.1752609 A 2 NA NA9.81 10 0.664864 0.60849 A 2 NA NA5.64 8 0.602244 -0.073539 A 2 NA NA

10.12 16 0.50655 0.7433182 B NA 1 NA16.07 4 0.431527 1.880908 C NA NA 16.28 14 0.531938 0.1063386 B NA 2 NA9.26 8 0.657746 0.2326548 A 2 NA NA9.65 8 0.453542 -0.118992 C NA NA 2

28.84 4 0.560956 0.5216669 C NA NA 26.68 8 0.635647 0.1559646 A 2 NA NA6.88 10 0.68723 0.2954547 A 2 NA NA8.97 16 0.670579 0.2593598 B NA 2 NA4.44 14 0.533526 0.3643472 B NA 2 NA9.59 8 0.683952 0.6965669 A 2 NA NA5.82 8 0.598008 0.2306083 A 2 NA NA

45.11 14 0.40048 0.195637 C NA NA 210.44 14 0.634582 0.2814138 B NA 2 NA6.00 8 0.670533 0.3605391 A 2 NA NA

Page 99 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

11.01 4 0.545104 0.2784996 C NA NA 210.69 8 0.66694 0.5468354 A 2 NA NA18.71 4 0.578838 0.3760785 C NA NA 225.15 10 0.609841 0.3293478 A 2 NA NA30.84 8 0.607869 0.3221425 A 2 NA NA27.20 8 0.560646 0.0067471 C NA NA 211.67 8 0.687948 0.7321798 A 2 NA NA8.70 8 0.675417 0.3512699 A 2 NA NA4.33 8 0.647046 0.3242396 A 2 NA NA4.81 16 0.306059 0.2945108 B NA 2 NA2.77 16 0.564041 0.4324811 B NA 2 NA3.39 10 0.610252 0.3342807 C NA NA 26.24 10 0.616139 0.9969784 B NA 2 NA6.34 6 0.552506 0.1952332 C NA NA 28.49 16 0.598696 0.4184778 B NA 2 NA

18.36 14 0.589156 0.1592995 B NA 2 NA5.38 8 0.622606 0.2812893 A 2 NA NA5.58 10 0.66877 0.2046555 A 2 NA NA2.06 8 0.690407 0.4128849 A 2 NA NA6.32 8 0.678747 0.3612832 A 2 NA NA2.93 8 0.663789 0.3059378 A 2 NA NA7.60 8 0.613078 0.1962433 A 2 NA NA7.78 16 0.589702 0.1079397 B NA 2 NA

59.94 8 0.427813 0.483059 C NA NA 26.54 10 0.696046 0.3710929 A 2 NA NA

16.15 10 0.67558 0.1976596 A 2 NA NA17.19 4 0.39688 0.3593407 C NA NA 24.88 18 0.674764 0.1449059 B NA 2 NA5.78 8 0.614558 0.399918 A 2 NA NA

29.29 4 0.35032 1.7676497 C NA NA 110.36 16 0.642883 0.3746993 B NA 2 NA6.75 4 0.55033 0.3785521 A 2 NA NA

12.76 8 0.609437 0.3002586 A 2 NA NA5.04 16 0.580822 0.3787035 B NA 2 NA4.31 16 0.662869 0.1529803 B NA 2 NA3.53 18 0.608357 0.1147748 B NA 1 NA

16.09 8 0.643697 1.5105582 A 1 NA NA2.68 8 0.678763 0.2143829 A 1 NA NA5.00 10 0.592997 0.071424 C NA NA 11.64 10 0.69126 0.7525404 B NA 1 NA

Page 100 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

2.88 8 0.609514 -0.039237 C NA NA 12.67 14 0.656816 0.1543786 B NA 1 NA2.37 18 0.461238 0.0707906 B NA 1 NA5.97 12 0.635724 0.3039074 B NA 1 NA5.01 8 0.464829 0.3744309 A 1 NA NA0.86 16 0.546123 0.1375649 B NA 1 NA4.94 8 0.540476 -0.463672 A 1 NA NA2.69 8 0.604194 0.3133514 C NA NA 19.62 8 0.691739 0.1791175 A 1 NA NA

12.49 8 0.66435 0.1952512 A 1 NA NA4.49 14 0.504997 -0.056239 B NA 1 NA3.34 16 0.494628 0.1153792 B NA 1 NA4.04 12 0.608771 0.200852 B NA 1 NA5.50 8 0.59085 0.1449291 C NA NA 15.67 8 0.646911 0.2751442 A 1 NA NA3.87 8 0.630563 0.1742972 C NA NA 1

10.59 8 0.642771 0.2048648 A 1 NA NA2.27 8 0.588153 -0.347434 C NA NA 15.20 8 0.621564 0.3304432 A 1 NA NA2.65 8 0.684864 0.1726541 A 1 NA NA2.71 8 0.601896 0.0160089 A 1 NA NA

13.11 16 0.556052 1.0362674 B NA 1 NA3.74 12 0.595578 0.1959271 B NA 1 NA3.48 12 0.564653 0.1922211 B NA 1 NA5.00 8 0.699301 0.2366331 A 1 NA NA4.96 8 0.69207 0.2032498 A 1 NA NA1.07 16 0.653761 0.1414361 B NA 1 NA3.77 8 0.662264 0.2164746 A 1 NA NA4.09 12 0.527529 0.1394763 C NA NA 14.49 12 0.534007 -0.046962 B NA 1 NA3.29 14 0.543705 0.1708133 B NA 1 NA9.01 12 0.571789 0.1726342 B NA 1 NA5.81 14 0.56867 0.0996806 B NA 1 NA

38.17 14 0.560519 0.0262615 B NA 1 NA6.86 8 0.703568 0.2757735 A 1 NA NA5.92 12 0.538061 0.285382 B NA 1 NA3.54 8 0.590312 0.1281533 C NA NA 11.57 8 0.535162 0.2587132 C NA NA 15.88 14 0.638301 0.3073109 B NA 1 NA5.10 12 0.709443 0.5549865 B NA 1 NA

Page 101 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

4.71 14 0.575333 0.1011792 B NA 1 NA4.08 8 0.631431 0.1025961 A 1 NA NA3.67 10 0.541817 0.1020276 B NA 1 NA5.33 12 0.605347 0.1955544 B NA 1 NA4.29 8 0.628032 0.3322248 A 1 NA NA3.03 16 0.654469 0.1911081 B NA 1 NA6.32 8 0.671451 0.2938768 A 1 NA NA5.26 8 0.684246 0.2891609 A 1 NA NA3.05 8 0.598824 0.1439579 C NA NA 15.47 14 0.5678 -0.059129 B NA 1 NA

12.64 14 0.667338 0.1003879 B NA 1 NA3.00 8 0.61955 0.2150339 C NA NA 13.05 8 0.686486 0.2950268 A 1 NA NA3.99 8 0.593528 0.3829327 C NA NA 1

23.72 10 0.347019 0.2447673 C NA NA 110.89 10 0.686745 0.4120859 A 1 NA NA5.30 8 0.668865 0.3654436 A 1 NA NA6.09 12 0.583837 0.1925304 B NA 1 NA4.54 8 0.600634 0.050319 A 1 NA NA

12.23 8 0.603693 -0.082371 A 1 NA NA12.66 14 0.650928 0.1878662 B NA 1 NA27.71 8 0.637912 0.1794352 C NA NA 13.36 8 0.605113 0.3746542 A 1 NA NA2.52 8 0.627187 0.4413897 A 1 NA NA4.89 16 0.616194 0.2065834 B NA 1 NA

16.02 16 0.549263 0.2103044 B NA 1 NA5.43 8 0.685345 0.33308 A 1 NA NA7.01 16 0.567791 0.0628583 B NA 1 NA3.22 8 0.687603 0.3326924 A 1 NA NA2.03 16 0.610487 0.1589924 B NA 1 NA

14.94 8 0.556254 0.1566904 C NA NA 14.49 10 0.629506 0.1477891 A 1 NA NA8.77 10 0.657953 0.2874566 B NA 1 NA

14.08 8 0.678378 0.3114464 A 1 NA NA5.82 12 0.611591 0.0893271 B NA 1 NA2.11 16 0.638728 -0.004163 B NA 1 NA3.39 18 0.596855 0.240572 B NA 1 NA0.93 16 0.59495 -0.108457 B NA 1 NA

17.09 10 0.625478 0.5811921 C NA NA 16.60 12 0.651592 0.1964814 B NA 1 NA

Page 102 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

3.93 8 0.688599 0.2167589 A NA NA 14.37 8 0.614945 0.279815 C 1 NA NA6.62 16 0.623864 0.082967 B NA 1 NA4.35 16 0.619165 0.1337407 B NA 1 NA2.96 8 0.738734 0.3114531 A 1 NA NA1.75 8 0.714148 0.2244653 A 1 NA NA6.48 10 0.578999 0.236419 C NA NA 16.71 8 0.515413 0.1711884 C NA NA 1

10.44 8 0.592419 0.0967887 A 1 NA NA17.04 16 0.4471 0.0945878 B NA 1 NA7.72 8 0.580771 0.4514206 A 1 NA NA5.19 8 0.63052 0.3896465 A 1 NA NA3.27 8 0.646683 0.094333 A 1 NA NA4.93 8 0.647428 0.2630451 A 1 NA NA5.76 8 0.588701 0.0038974 A 1 NA NA7.80 8 0.671073 0.1861473 A 1 NA NA2.13 14 0.584236 0.2631636 B NA 1 NA3.37 8 0.651924 0.3002807 A 1 NA NA9.63 8 0.5648 -0.005886 C NA NA 12.94 22 0.62574 -0.023865 B NA 2 NA1.58 12 0.610524 0.1931895 B NA 1 NA4.05 14 0.579219 0.0728209 B NA 1 NA5.25 16 0.518638 0.367711 B NA 1 NA5.57 8 0.559242 0.054527 C NA NA 15.06 8 0.631778 0.0476983 A 1 NA NA5.38 8 0.592798 0.165312 A 1 NA NA2.68 8 0.666631 0.4418785 A 1 NA NA3.28 8 0.687084 0.3197324 A 1 NA NA2.80 8 0.619724 0.1416554 A 1 NA NA

16.65 4 0.579762 1.4043443 C NA NA 13.19 14 0.593144 0.2377288 B NA 1 NA4.37 8 0.672212 0.2656412 A 1 NA NA3.31 8 0.666911 0.2312394 A 1 NA NA6.44 8 0.63092 0.0943457 A 1 NA NA5.35 8 0.665598 0.4184655 A 1 NA NA3.83 8 0.653111 0.5428847 A 1 NA NA4.17 12 0.649509 0.147622 B NA 1 NA1.70 12 0.635944 0.1477007 B NA 1 NA5.45 8 0.715974 0.192245 A 1 NA NA

11.66 8 0.541083 0.2005681 C NA NA 1

Page 103 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

3.86 12 0.614535 0.4090832 B NA 1 NA2.96 8 0.699518 0.3982114 A 1 NA NA6.18 8 0.653209 0.1454924 A 1 NA NA

14.36 8 0.674372 0.261843 A 2 NA NA12.01 10 0.644872 0.2829258 A 2 NA NA6.13 44 0.235742 2.0118875 C NA NA 1

15.47 8 0.656662 0.5198047 A 2 NA NA3.31 10 0.636965 0.4089187 A 2 NA NA

10.06 8 0.674713 0.3689317 A 2 NA NA1.64 10 0.52824 0.2667024 B NA 2 NA6.03 8 0.690313 0.3248721 A 2 NA NA8.24 8 0.596192 0.2229318 C NA NA 23.58 8 0.439542 -0.069078 C NA NA 24.26 12 0.468099 0.3390188 B NA 1 NA

11.17 6 0.294882 0.131152 C NA NA 14.29 4 0.247775 0.2998889 C NA NA 14.26 8 0.559801 -0.183111 C NA NA 22.83 14 0.342589 0.1559048 C NA NA 16.60 8 0.551795 -0.004554 C NA NA 28.21 8 0.66301 0.2794646 A 2 NA NA6.07 6 0.540458 0.2959047 C NA NA 24.48 8 0.589611 0.2852859 C NA NA 2

12.08 42 0.232911 2.2585364 C NA NA 13.19 8 0.59403 0.1584864 A 2 NA NA4.62 10 0.650692 0.3113439 B NA 2 NA8.21 8 0.285682 0.2179638 C NA NA 12.89 8 0.422348 0.2535494 C NA NA 22.43 10 0.658799 0.4004849 A 2 NA NA5.82 8 0.675885 0.3517494 A 2 NA NA3.67 8 0.690095 0.3198383 A 2 NA NA6.56 8 0.610061 0.274603 C NA NA 22.29 44 0.135932 0.3360664 C NA NA 12.97 8 0.612535 0.4831784 A 1 NA NA1.67 8 0.621518 0.2474551 A 1 NA NA5.10 8 0.5924 0.0176916 C NA NA 11.72 12 0.621249 0.2818105 B NA 1 NA2.15 8 0.645743 0.1150222 A 1 NA NA2.59 8 0.664912 0.328361 A 1 NA NA2.60 8 0.63818 0.1322103 A 1 NA NA2.82 8 0.632635 0.3991925 A 1 NA NA

Page 104 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

2.65 8 0.556188 0.00919 A 1 NA NA5.56 8 0.610683 0.0878644 B NA 1 NA5.50 10 0.651138 0.2801174 A 2 NA NA5.42 8 0.624127 0.4245716 A 2 NA NA3.40 8 0.689135 0.2969921 A 2 NA NA5.27 10 0.637813 0.1931763 B NA 2 NA

10.88 8 0.599878 0.4759371 A 2 NA NA9.13 16 0.60872 0.3160329 B NA 2 NA3.66 8 0.619167 0.108674 A 2 NA NA5.91 10 0.661629 0.204387 A 2 NA NA8.70 10 0.687117 0.3317882 A 2 NA NA5.24 14 0.341582 0.277779 C NA NA 18.43 8 0.631637 0.3615679 A 2 NA NA7.47 8 0.672668 0.688556 A 1 NA NA6.14 16 0.508716 0.1292981 B NA 2 NA3.32 10 0.502251 0.3640697 C NA NA 16.48 14 0.533294 0.3652402 B NA 1 NA

10.57 14 0.658505 0.3226889 B NA 1 NA4.37 8 0.621411 0.2567938 A 1 NA NA3.40 8 0.63124 0.3154751 A 1 NA NA4.11 8 0.666161 0.5042957 A 1 NA NA3.95 8 0.624793 0.1741251 A 1 NA NA1.19 8 0.625576 0.3459525 B NA 1 NA1.84 8 0.651161 0.3281185 A 1 NA NA1.11 4 0.53785 0.2295852 C NA NA 13.06 8 0.618736 0.3611431 A 1 NA NA5.14 8 0.608313 0.2863683 A 1 NA NA6.35 14 0.447485 0.537486 C NA NA 12.77 8 0.657142 0.4000603 A 1 NA NA3.71 4 0.200299 0.1514643 C NA NA 13.99 8 0.679219 0.430006 A 1 NA NA1.50 8 0.580759 0.2697104 C NA NA 15.29 8 0.670748 0.3033032 A 1 NA NA9.61 8 0.644635 0.2795474 C NA NA 11.55 12 0.653044 0.3760684 B NA 1 NA4.65 8 0.452806 -0.070805 C NA NA 18.40 8 0.689911 0.3283843 A 1 NA NA6.59 8 0.579809 0.3093143 C NA NA 13.27 8 0.685949 0.3739149 A 1 NA NA4.05 8 0.706698 0.4069139 A 1 NA NA

Page 105 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

4.08 8 0.699701 0.2966581 A 1 NA NA3.53 8 0.668425 0.3316155 A 1 NA NA2.39 8 0.634676 0.2111456 C NA NA 15.08 12 0.608078 0.2317588 B NA 1 NA3.22 8 0.702045 0.4327052 A 1 NA NA3.19 8 0.679451 0.2792886 C NA NA 12.65 4 0.587527 0.1090855 C NA NA 15.39 8 0.671018 0.2165217 A 1 NA NA9.92 8 0.717143 0.2589863 A 1 NA NA5.39 8 0.687743 0.2182993 A 1 NA NA2.98 8 0.713623 0.3896747 A 1 NA NA3.39 8 0.646369 0.3146679 A 1 NA NA2.81 8 0.597067 0.1701472 A 1 NA NA4.51 8 0.727082 0.4076987 A 1 NA NA4.28 4 0.61473 0.4058381 A 1 NA NA3.39 12 0.648504 0.3513268 B NA 1 NA1.24 8 0.64591 0.0912013 A 1 NA NA5.96 8 0.645443 0.1982347 A 1 NA NA3.45 8 0.664392 0.3081248 A 1 NA NA

13.50 4 0.575529 0.3447351 C NA NA 15.90 8 0.705073 0.4079054 A 1 NA NA5.72 8 0.581601 0.1837103 C NA NA 13.27 8 0.62673 0.0596011 A 1 NA NA8.74 12 0.673462 0.1841772 B NA 1 NA5.06 10 0.614251 0.3729411 B NA 1 NA4.65 10 0.593682 0.4678467 A 1 NA NA9.65 12 0.665345 0.2037665 B NA 1 NA2.92 8 0.646352 0.1251924 C NA NA 15.84 8 0.693197 0.3184649 A 1 NA NA3.46 8 0.648156 0.0269661 A 1 NA NA6.26 8 0.539002 0.1669971 C NA NA 13.75 8 0.630153 0.1658386 A 1 NA NA6.00 8 0.569116 0.135395 A 1 NA NA5.18 8 0.637035 0.4178231 A 1 NA NA4.87 8 0.663 0.4404946 A 1 NA NA

26.43 8 0.54205 0.2807938 C NA NA 12.37 8 0.668952 0.2826638 A 1 NA NA3.42 10 0.679216 0.1966076 B NA 1 NA1.13 10 0.61634 0.4648606 B NA 1 NA2.25 8 0.68179 0.4958798 A 1 NA NA

Page 106 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

4.76 4 0.518188 0.1878545 C NA NA 122.75 8 0.64108 1.1217385 C NA NA 11.29 8 0.567195 0.3091323 C NA NA 12.42 8 0.617865 0.3304067 A 1 NA NA3.79 8 0.662926 0.2932244 A 1 NA NA1.85 8 0.682481 0.2840596 A 1 NA NA0.91 8 0.705761 0.424228 A 1 NA NA3.91 10 0.608746 0.2433956 B NA 1 NA0.79 8 0.596934 0.3882142 C NA NA 12.88 16 0.567728 0.0696997 B NA 1 NA2.02 12 0.617101 0.1538731 B NA 1 NA1.78 4 0.536071 0.3699088 A 1 NA NA2.14 8 0.569272 0.1588743 C NA NA 11.67 8 0.642635 0.3218548 A 1 NA NA2.59 8 0.709113 0.4218618 A 1 NA NA2.67 8 0.533944 -0.063463 C NA NA 14.99 14 0.572283 0.0969512 B NA 1 NA3.32 8 0.665814 0.1738954 A 1 NA NA3.15 8 0.688349 0.2716373 A 1 NA NA5.49 8 0.70682 0.2699186 A 1 NA NA7.66 4 0.482904 0.2308671 C NA NA 1

11.86 8 0.62547 0.2731228 A 1 NA NA2.29 8 0.710002 0.2877286 A 1 NA NA2.89 8 0.689627 0.2408361 A 1 NA NA3.02 10 0.677396 0.2638658 B NA 1 NA4.90 14 0.671909 0.1909195 B NA 1 NA2.92 8 0.723169 0.3880512 A 1 NA NA6.06 8 0.663522 0.4135117 A 1 NA NA6.06 8 0.699264 0.4970295 A 1 NA NA2.15 44 0.096557 -0.017595 C NA NA 13.01 8 0.713246 0.3009466 A 1 NA NA4.57 12 0.571406 0.1004662 B NA 1 NA3.25 8 0.723805 0.2749336 A 1 NA NA2.70 8 0.598067 0.4421277 A 1 NA NA3.17 8 0.692583 0.4613772 A 1 NA NA

11.11 8 0.577875 0.3004558 A 1 NA NA11.79 8 0.662212 0.3003982 A 1 NA NA3.70 8 0.688444 0.4675924 A 1 NA NA4.18 8 0.706068 0.2240294 A 1 NA NA1.88 8 0.667114 0.3159828 A 1 NA NA

Page 107 of 135


Field site

color


RNA yield (ug)

Asexual stage (hpi)

SRCC asexual stage

mean gam. exp

ratio

Kmeans Grp

GrpA subtype

GrpB subtype

GrpC subtype

5.76 10 0.659496 0.2805459 A 1 NA NA2.27 14 0.381845 0.1365651 B NA 1 NA2.67 8 0.520655 0.2866455 C NA NA 16.18 8 0.54464 0.2177206 C NA NA 14.84 8 0.459558 0.0978783 C NA NA 15.21 8 0.639613 0.147065 A 1 NA NA

Page 108 of 135


Field site

color



K13 (KP/BT

B)

crt-N326S crt-I356T fd-D193Y mdr2-

T484Iarps10-V127M

1 0 0 1 1 11 2 2 1 1 11 1 2 1 1 11 1 2 1 1 11 0 2 1 3 11 0 0 0 1 11 2 2 2 1 11 2 2 1 1 11 1 1 1 1 11 1 2 1 1 11 2 2 1 2 1

NA NA NA NA NA NA1 0 1 1 1 11 0 3 1 3 01 2 2 1 1 11 1 2 1 1 11 1 2 1 1 11 0 2 1 1 1

NA NA NA NA NA NA1 1 2 1 1 11 1 2 1 1 11 2 2 1 1 11 1 2 1 1 11 3 2 1 1 11 0 2 1 1 11 1 2 1 1 1

NA NA NA NA NA NANA NA NA NA NA NA1 1 2 1 3 11 1 2 1 3 11 2 2 1 1 11 1 2 1 1 11 0 1 1 1 11 3 2 1 1 11 2 2 1 1 11 2 2 3 1 11 1 2 1 1 1

Page 109 of 135


Field site

color


K13 (KP/BT

B)


T484Iarps10-V127M

1 3 2 1 1 1NA NA NA NA NA NA1 0 3 1 1 11 0 2 1 1 11 1 2 1 1 11 1 2 1 1 11 1 2 1 1 11 2 2 1 2 11 1 2 1 1 11 1 2 1 1 11 0 0 1 1 11 3 2 1 3 11 2 2 1 1 11 0 2 1 2 11 0 2 1 1 11 1 2 1 1 11 1 1 1 1 11 1 1 1 1 11 1 2 1 1 11 1 1 1 1 11 1 2 1 1 11 0 0 0 1 01 1 3 1 1 11 1 1 1 1 11 1 1 1 1 11 1 3 1 1 11 1 1 1 1 11 1 1 1 1 11 0 1 1 1 11 1 1 1 1 11 1 3 1 1 11 1 3 1 1 11 1 3 1 1 1

NA NA NA NA NA NA1 1 1 1 1 11 1 2 1 1 11 1 3 1 1 11 1 1 1 1 11 1 2 1 1 11 1 3 1 1 1

Page 110 of 135


Field site

color


K13 (KP/BT

B)


T484Iarps10-V127M

3 1 3 1 1 11 1 1 1 1 11 1 1 1 1 11 1 1 1 1 11 1 1 1 1 11 1 1 1 1 11 1 1 1 1 11 0 3 1 1 11 1 1 1 1 11 1 1 1 1 11 1 1 1 1 11 1 2 1 1 11 0 2 1 1 11 0 1 1 1 11 0 1 0 1 1

NA NA NA NA NA NA1 0 0 1 1 11 1 1 1 1 11 1 1 1 1 1

NA NA NA NA NA NA1 1 3 1 1 01 0 0 1 1 01 1 1 1 1 11 0 1 1 1 01 0 1 1 1 11 1 1 1 1 11 1 1 1 1 11 1 1 1 1 11 0 1 1 1 11 1 3 1 1 11 1 1 1 1 11 1 3 1 1 1

NA NA NA NA NA NA1 1 1 1 1 11 0 3 1 1 11 1 3 1 1 11 1 1 1 1 11 1 2 1 1 11 1 2 1 1 11 0 2 1 1 1

Page 111 of 135


Field site

color


K13 (KP/BT

B)


T484Iarps10-V127M

1 1 3 1 1 11 1 1 1 1 13 1 2 1 1 13 0 2 1 1 11 1 1 1 1 11 0 1 1 1 11 1 2 2 1 11 1 1 1 1 11 1 3 1 1 11 1 2 1 1 11 0 1 1 1 11 1 3 1 1 11 1 2 1 1 11 1 2 1 1 11 1 2 1 1 11 1 3 1 1 13 1 1 1 1 11 0 0 0 1 11 1 1 1 1 11 1 1 1 1 11 1 1 1 1 1

NA NA NA NA NA NA1 1 1 1 1 11 0 0 0 1 01 1 1 1 1 13 1 1 1 1 11 1 1 1 1 13 0 1 1 1 11 1 1 1 1 11 1 2 1 1 11 1 1 1 1 13 1 0 1 1 1

NA NA NA NA NA NA1 1 3 1 1 11 1 0 1 1 01 1 1 1 1 11 1 1 1 1 11 0 3 1 1 13 0 2 1 1 11 0 1 1 1 1

Page 112 of 135


Field site

color


K13 (KP/BT

B)


T484Iarps10-V127M

1 0 1 1 1 11 0 1 1 1 11 0 0 1 1 11 0 1 1 1 11 0 0 0 1 11 1 1 1 1 11 1 1 1 1 11 0 2 1 1 11 1 1 1 1 11 1 1 1 1 11 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 1 22 0 2 2 2 22 2 2 2 2 22 2 2 2 2 21 2 2 2 2 23 2 2 2 2 21 2 2 2 2 31 0 2 2 2 32 2 2 2 2 22 2 2 2 1 22 2 2 2 1 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 21 2 2 2 2 12 2 2 2 2 21 2 2 2 2 12 2 2 2 2 23 3 3 2 3 22 2 2 2 1 21 2 2 2 2 32 2 2 2 2 22 2 2 2 2 2

Page 113 of 135


Field site

color


K13 (KP/BT

B)


T484Iarps10-V127M

2 2 2 2 2 31 2 2 2 1 21 2 2 2 2 22 2 2 2 2 23 2 2 2 2 21 3 3 2 2 12 1 1 2 2 2

NA NA NA NA NA NA3 2 2 3 2 23 2 2 2 2 2

NA NA NA NA NA NA1 2 2 0 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 21 2 2 2 2 11 2 2 2 1 22 2 2 2 2 22 2 2 2 3 22 2 2 2 2 22 2 2 2 2 22 0 0 0 2 22 2 2 2 2 23 2 2 2 2 22 2 2 2 2 2

NA NA NA NA NA NA2 0 0 0 0 0

NA NA NA NA NA NANA NA NA NA NA NA2 0 2 2 2 2

NA NA NA NA NA NA2 0 2 2 2 22 0 2 2 2 22 0 2 2 2 22 0 2 2 2 21 0 2 2 2 0

NA NA NA NA NA NA3 2 2 2 2 22 2 2 1 2 2

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T484Iarps10-V127M

2 2 2 2 2 11 2 2 2 3 32 0 2 0 0 02 0 2 2 2 22 0 2 2 2 22 0 2 2 2 21 2 2 2 2 2

NA NA NA NA NA NANA NA NA NA NA NA2 2 2 2 2 23 3 3 3 3 33 0 2 2 2 02 2 2 2 2 22 2 2 2 2 21 0 3 2 2 12 2 2 2 2 22 2 2 2 2 2

NA NA NA NA NA NANA NA NA NA NA NA2 2 2 2 2 22 2 2 2 2 23 2 2 2 3 21 0 2 0 2 13 3 3 3 2 3



NA NA NA NA NA NA3 2 2 2 2 31 2 2 2 3 33 3 3 3 2 13 2 2 2 2 21 3 3 1 3 3

NA NA NA NA NA NA1 1 1 1 1 12 0 0 0 0 03 1 1 1 1 22 2 2 2 2 22 2 2 2 2 2

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T484Iarps10-V127M

1 1 1 1 1 11 2 2 2 1 21 2 2 1 1 12 2 2 2 1 21 2 2 1 1 11 2 2 1 1 12 2 2 2 2 21 1 1 1 2 12 2 2 2 2 21 1 1 1 1 12 2 2 2 2 22 2 2 2 2 21 1 1 1 3 11 1 1 1 1 11 1 1 3 3 11 1 1 1 1 11 2 3 3 1 31 3 3 1 1 13 3 3 3 3 32 2 2 1 2 21 1 1 1 1 11 1 1 1 1 11 1 1 1 1 11 1 1 1 1 11 2 2 2 1 22 2 2 2 2 21 1 1 1 3 11 1 1 1 1 11 2 2 2 1 2

NA NA NA NA NA NANA NA NA NA NA NA1 0 0 0 2 21 1 1 1 2 21 0 0 1 1 12 0 2 2 2 2

NA NA NA NA NA NA1 0 1 0 1 01 1 1 1 2 21 0 1 1 1 02 0 2 2 2 2

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1 1 1 1 1 03 3 3 1 2 21 1 1 1 3 33 0 3 1 2 21 1 1 3 3 31 1 1 0 1 12 0 2 2 2 21 1 1 1 2 1

NA NA NA NA NA NA3 3 3 3 3 31 0 0 2 1 21 0 2 0 1 21 0 2 0 2 02 0 0 0 2 21 1 1 2 1 11 3 3 1 1 1

NA NA NA NA NA NA1 0 0 0 1 11 0 1 3 1 0

NA NA NA NA NA NA1 1 1 1 1 12 2 2 2 2 21 0 1 1 1 12 2 2 2 2 21 0 1 2 1 12 0 2 2 2 21 0 1 2 1 21 0 1 1 2 11 1 1 1 1 11 1 1 1 1 11 2 2 2 2 21 1 1 1 1 21 1 1 1 1 2


NA NA NA NA NA NA3 2 2 2 2 21 2 2 2 2 21 1 1 1 2 21 0 2 0 1 0

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2 2 2 2 2 21 0 1 1 1 11 1 1 1 3 31 0 0 0 1 0

NA NA NA NA NA NA1 1 1 1 2 01 1 1 1 2 21 1 1 1 1 13 2 2 1 1 11 1 1 1 1 11 1 1 1 1 11 1 1 1 2 21 1 1 0 1 01 1 1 1 3 21 1 1 1 1 1


NA NA NA NA NA NANA NA NA NA NA NA1 1 1 1 1 11 1 1 1 2 11 2 2 1 1 01 1 1 1 2 21 1 1 1 2 21 2 2 2 1 2

NA NA NA NA NA NANA NA NA NA NA NANA NA NA NA NA NA1 0 1 0 1 11 1 1 1 3 11 1 1 1 1 31 1 1 1 1 31 1 1 2 1 10 0 0 0 1 01 1 1 1 1 11 1 1 1 1 11 0 0 0 1 01 1 1 1 2 0


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1 1 1 1 1 11 1 1 1 1 11 2 2 1 2 11 1 1 1 3 11 1 1 3 1 11 1 1 1 1 11 1 1 1 1 11 1 1 1 2 11 1 1 1 3 11 1 1 1 1 21 1 1 1 1 21 0 1 1 1 13 1 1 1 2 11 1 1 1 2 11 1 1 1 1 11 3 3 1 1 11 1 1 1 1 11 1 1 1 1 11 1 1 1 1 11 1 1 1 3 11 1 1 1 3 11 1 1 1 1 11 1 1 1 1 1

NA NA NA NA NA NA1 1 1 1 1 11 0 1 1 2 11 0 0 0 1 11 0 0 1 1 11 1 1 1 3 11 0 1 1 3 11 0 1 1 3 11 1 1 1 3 11 0 1 1 2 2

NA NA NA NA NA NA1 1 1 1 2 11 2 2 1 1 11 1 1 1 2 11 2 2 2 1 11 0 1 1 1 11 0 1 1 3 1

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1 1 1 1 1 11 0 1 1 1 1

NA NA NA NA NA NA1 0 1 1 1 21 0 1 1 2 12 1 1 1 1 11 1 1 1 1 12 1 1 1 1 1

NA NA NA NA NA NA1 1 1 1 1 21 0 1 1 1 11 1 1 1 1 1

NA NA NA NA NA NANA NA NA NA NA NA1 0 0 1 2 11 1 1 1 1 11 1 1 1 1 1


NA NA NA NA NA NANA NA NA NA NA NA1 1 1 1 3 31 0 1 1 1 11 1 1 1 1 1



NA NA NA NA NA NA1 0 1 1 1 11 1 1 1 1 1

NA NA NA NA NA NA1 0 1 1 1 11 1 1 0 1 11 1 1 3 1 11 0 1 0 1 01 1 1 1 2 21 1 1 1 2 21 2 2 1 1 1

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1 1 1 1 1 1NA NA NA NA NA NANA NA NA NA NA NA1 1 1 2 1 21 1 1 1 1 1

NA NA NA NA NA NA1 1 1 1 1 31 1 1 1 1 11 1 1 1 1 11 0 1 1 1 11 1 1 1 1 11 1 1 1 3 01 1 1 1 3 11 0 0 1 1 1

NA NA NA NA NA NA3 2 2 2 2 23 2 2 2 2 23 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 23 2 2 2 2 22 2 2 2 3 22 2 2 2 2 23 0 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 23 2 2 2 2 23 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 2

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T484Iarps10-V127M

2 2 2 2 2 23 2 2 2 2 23 2 2 2 2 23 2 2 2 3 22 2 2 2 2 22 2 2 2 2 21 0 1 1 1 11 1 1 1 3 12 2 2 2 2 21 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 21 0 2 2 2 0

NA NA NA NA NA NA2 2 2 2 2 22 2 2 2 2 22 2 2 2 2 21 2 2 2 2 2


NA NA NA NA NA NA3 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 0 2 2 2 23 2 2 3 3 22 2 2 2 2 23 2 2 2 2 33 0 2 2 2 2

NA NA NA NA NA NA2 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 0 2 2 2 22 0 2 2 2 0

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2 0 2 2 2 2NA NA NA NA NA NANA NA NA NA NA NA2 2 2 2 2 23 2 3 3 3 32 2 2 2 2 22 2 2 2 2 2

NA NA NA NA NA NA2 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 2


NA NA NA NA NA NANA NA NA NA NA NA2 2 2 2 2 22 2 2 2 2 2

NA NA NA NA NA NANA NA NA NA NA NA2 2 2 2 2 21 1 1 2 1 12 2 2 2 2 22 2 2 2 2 22 2 2 2 2 21 1 1 1 1 11 1 1 1 1 1


NA NA NA NA NA NA1 1 1 1 1 11 1 1 1 1 11 1 1 1 1 13 1 1 1 3 11 1 1 1 1 11 1 1 1 1 11 1 1 1 3 11 1 1 1 1 11 1 1 1 1 1

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1 1 1 1 1 11 1 1 1 1 1

NA NA NA NA NA NANA NA NA NA NA NA1 0 1 1 1 31 1 1 1 1 11 1 1 1 1 11 1 1 1 1 11 2 3 1 1 11 1 3 1 1 11 1 1 1 1 11 2 2 1 1 11 1 1 1 1 11 1 1 1 1 11 1 1 1 1 11 1 1 1 3 31 1 1 1 3 11 2 2 1 2 21 1 1 1 1 11 1 1 1 3 31 0 1 1 1 21 1 1 1 3 11 1 1 1 2 12 1 1 1 1 11 1 1 1 1 11 2 2 1 2 21 1 1 1 1 11 1 1 1 1 11 1 1 1 1 11 2 2 1 2 21 3 3 1 3 11 1 1 1 1 11 1 1 1 1 11 1 1 1 1 31 1 1 1 1 11 1 1 1 3 11 1 1 1 3 11 1 1 1 1 11 2 2 2 1 11 1 1 1 3 2

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1 1 1 1 3 11 1 1 3 2 31 1 1 1 1 11 0 1 0 1 1

NA NA NA NA NA NA1 1 1 1 1 11 1 3 1 3 31 2 2 3 2 31 1 1 1 2 11 1 1 1 1 12 2 2 1 2 21 1 1 1 1 11 0 2 1 2 21 1 1 1 1 11 2 2 1 2 21 1 1 1 1 1

NA NA NA NA NA NA1 1 1 1 2 21 1 1 1 2 11 1 1 1 2 11 1 1 1 3 11 1 1 1 2 2

NA NA NA NA NA NA1 2 2 2 1 21 1 1 1 1 1

NA NA NA NA NA NA1 1 1 1 1 11 1 3 1 3 21 1 1 1 2 11 1 1 1 2 11 1 1 1 2 11 2 2 1 1 11 1 1 1 1 11 2 2 3 2 12 2 2 1 2 21 2 3 1 1 21 2 2 3 1 31 2 2 2 3 31 2 2 2 3 31 2 2 2 3 1

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1 2 2 2 3 11 0 2 1 1 11 2 2 1 2 11 2 2 1 2 12 2 2 2 2 11 2 2 3 3 12 2 2 2 2 11 2 2 2 2 11 0 2 2 2 11 2 1 1 1 13 2 2 3 3 31 2 2 2 2 1

NA NA NA NA NA NA1 2 2 2 2 11 2 2 2 2 12 2 2 2 1 12 2 2 2 1 13 2 2 1 1 21 2 2 1 2 11 2 2 2 2 11 2 2 2 2 2

NA NA NA NA NA NANA NA NA NA NA NANA NA NA NA NA NA1 2 2 2 2 23 0 2 1 2 11 2 2 1 2 11 2 2 2 2 21 2 2 2 2 2

NA NA NA NA NA NA1 2 2 2 2 23 2 2 1 3 33 2 2 1 3 12 2 2 2 2 1

NA NA NA NA NA NANA NA NA NA NA NA1 2 2 1 2 11 2 2 2 1 12 2 2 1 2 11 2 2 2 2 2

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NA NA NA NA NA NA2 2 2 1 1 22 2 2 3 2 11 2 2 2 2 21 2 2 2 3 2

NA NA NA NA NA NA2 2 2 1 1 12 2 2 2 2 11 2 2 2 2 1

NA NA NA NA NA NANA NA NA NA NA NANA NA NA NA NA NA1 2 2 2 1 21 2 2 2 2 11 2 2 1 1 11 2 2 2 2 11 0 2 1 1 1

NA NA NA NA NA NA1 2 2 2 2 11 2 2 2 2 11 0 2 2 2 31 2 2 1 2 12 0 2 2 1 2

NA NA NA NA NA NA1 2 2 2 2 11 0 2 2 2 1


NA NA NA NA NA NANA NA NA NA NA NANA NA NA NA NA NA1 2 2 2 2 1


NA NA NA NA NA NA2 2 2 2 2 21 2 2 3 3 31 2 2 1 1 12 2 2 2 2 2

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NA NA NA NA NA NA3 0 2 2 2 21 2 2 1 2 22 2 2 1 1 01 2 2 2 2 32 2 2 2 2 22 2 2 2 2 11 2 2 2 2 12 0 2 1 2 22 0 0 0 2 22 2 2 2 2 21 2 2 2 1 11 2 2 2 2 12 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 1

NA NA NA NA NA NA3 2 2 2 2 23 0 2 2 2 23 0 2 2 2 22 2 2 2 2 12 2 2 2 2 11 0 0 2 2 22 2 2 2 3 2

NA NA NA NA NA NA1 2 2 2 2 22 2 2 2 2 23 2 2 2 2 32 2 2 2 2 23 2 2 2 2 21 2 2 2 2 23 2 2 2 2 23 2 2 2 2 3

NA NA NA NA NA NA2 2 2 2 1 22 2 2 2 2 2

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NA NA NA NA NA NA2 2 2 2 2 23 2 2 1 1 12 2 2 2 2 13 2 2 1 1 1

NA NA NA NA NA NA1 2 2 2 3 22 2 2 2 2 23 0 2 2 2 22 2 2 2 2 22 2 2 1 1 12 2 2 2 1 12 2 2 2 2 23 2 2 2 2 23 0 2 2 0 21 2 2 2 2 23 2 2 2 2 23 2 2 2 2 32 2 2 2 2 21 2 2 2 2 23 2 2 2 2 32 2 2 2 2 22 2 2 2 1 13 2 2 2 1 21 2 2 1 1 1

NA NA NA NA NA NA1 2 2 2 2 22 0 2 2 2 21 2 2 2 2 22 0 2 1 2 12 2 2 2 1 22 2 2 2 2 23 2 2 2 2 22 2 2 2 2 23 2 2 2 2 21 2 2 2 3 21 2 2 2 2 21 0 2 2 1 21 2 2 3 3 21 2 2 2 1 2

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1 2 2 2 1 21 2 2 2 1 23 2 2 2 2 23 2 2 2 2 23 2 2 2 3 23 2 2 2 3 2


NA NA NA NA NA NA1 2 2 1 2 21 2 2 2 2 23 2 2 2 2 22 2 2 2 1 22 2 2 2 1 23 0 2 2 2 22 2 2 2 2 22 2 2 2 2 12 2 2 2 1 21 0 0 0 2 02 2 2 2 2 12 2 2 2 2 2


NA NA NA NA NA NA2 0 2 2 2 22 2 2 2 2 22 2 2 2 2 23 2 2 2 2 21 2 2 2 2 2

NA NA NA NA NA NA3 2 2 2 2 22 2 2 2 2 22 2 2 2 1 22 2 2 2 2 21 2 2 1 1 22 2 2 2 2 2


NA NA NA NA NA NA

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2 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 2 2 2 2 23 2 2 2 2 2

NA NA NA NA NA NA3 3 3 2 3 33 2 2 2 1 22 2 2 2 2 2


NA NA NA NA NA NANA NA NA NA NA NANA NA NA NA NA NANA NA NA NA NA NANA NA NA NA NA NANA NA NA NA NA NANA NA NA NA NA NA2 2 2 2 2 22 2 2 2 2 21 2 2 2 1 2

NA NA NA NA NA NA2 2 2 2 2 22 2 2 2 2 22 2 2 2 2 22 0 0 0 2 0



NA NA NA NA NA NA2 2 2 2 2 22 2 2 2 2 23 2 2 2 2 23 0 2 2 2 22 2 2 2 2 21 2 2 2 3 12 2 2 2 2 22 0 2 2 2 2

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3 2 2 1 2 1NA NA NA NA NA NA2 2 2 2 2 21 2 2 2 1 22 2 2 2 2 12 2 2 2 2 11 2 2 3 3 21 2 2 2 1 22 2 2 2 2 1

NA NA NA NA NA NA1 2 1 2 1 12 2 2 2 2 23 2 2 2 2 22 2 2 1 1 21 1 1 1 3 11 1 1 1 3 12 1 1 2 3 32 0 1 2 3 11 2 2 1 1 12 2 2 2 2 11 2 2 1 1 13 3 3 3 3 31 2 2 1 1 11 2 2 1 3 32 0 1 1 2 22 1 1 1 2 21 3 3 3 3 31 1 1 1 1 11 1 1 1 1 2

NA NA NA NA NA NA1 1 1 1 1 11 1 1 3 1 31 1 1 1 1 12 2 2 2 2 2



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1 2 2 3 3 13 3 3 1 1 11 1 1 1 2 13 3 2 2 3 33 1 1 2 1 12 0 2 2 2 22 2 2 2 2 23 2 2 3 3 12 1 1 2 1 1

NA NA NA NA NA NA1 2 2 1 1 11 1 1 1 1 11 0 2 1 1 11 2 2 1 2 21 1 1 1 1 32 2 2 2 2 22 2 2 2 2 21 1 1 1 1 11 1 1 1 1 11 2 2 1 1 13 1 1 3 3 31 0 1 1 1 13 2 2 2 2 21 1 2 2 2 13 2 2 2 2 22 0 2 2 2 21 1 1 2 2 12 2 2 2 2 21 1 1 1 2 13 2 3 3 2 21 2 2 1 3 12 2 2 2 2 21 1 1 1 3 11 1 1 1 3 11 1 1 2 1 11 0 1 1 2 11 1 1 1 2 12 2 2 2 2 22 2 2 2 2 2

NA NA NA NA NA NA

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1 1 1 1 1 13 2 3 1 2 1


NA NA NA NA NA NA1 2 2 1 1 11 1 1 1 1 12 2 2 1 2 2



NA NA NA NA NA NA1 2 2 1 2 13 2 2 2 2 2

NA NA NA NA NA NA1 1 1 1 1 11 1 1 1 2 12 2 2 2 2 21 1 1 1 2 1

NA NA NA NA NA NA1 3 2 2 1 12 2 2 2 2 21 2 2 2 1 12 2 2 2 2 23 1 1 1 2 13 2 3 2 2 23 3 3 3 2 32 2 2 2 2 2


NA NA NA NA NA NA1 1 1 1 2 11 1 1 1 3 11 1 1 1 1 11 1 1 2 2 11 1 1 1 1 21 1 1 1 2 1

NA NA NA NA NA NANA NA NA NA NA NA

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3 1 3 2 3 21 2 2 1 1 1


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Gene ID AnnotationER net-work Annotated Biological Process (GO) Rank

Correl. Coef.

corrected p-value

PF3D7_1115600 peptidyl-prolyl cis-trans isomerase CYPB GO-0006457-protein folding 1 0.35 0.0E+00PF3D7_0410900 conserved Plasmodium protein, unknown function 2 0.35 0.0E+00PF3D7_1372000 Plasmodium exported protein (PHISTa), unknown function 3 0.34 2.8E-13PF3D7_1010700 dolichyl-phosphate-mannose protein mannosyltransferase SDF2L1 4 0.34 3.7E-13PF3D7_1451300 conserved Plasmodium protein, unknown function 5 0.34 9.0E-13PF3D7_0424700 serine/threonine protein kinase, FIKK family GO-0006468-protein phosphorylation 6 0.31 8.3E-11PF3D7_0515200 conserved Plasmodium protein, unknown function 7 0.31 8.4E-11PF3D7_0831000 Plasmodium exported protein (PHISTb), unknown function 8 0.31 2.1E-10PF3D7_1038700 Plasmodium exported protein, unknown function 9 0.30 6.5E-10PF3D7_1412500 actin II GO-0007010-cytoskeleton organization 10 0.30 5.2E-10PF3D7_1027900 palmitoyltransferase, putative 11 0.30 5.5E-10PF3D7_0108700 secreted ookinete protein, putative 12 0.29 8.4E-10PF3D7_1231600 pre-mRNA-splicing factor ATP-dependent RNA helicase PRP2 GO-0008380-RNA splicing 13 0.29 1.3E-09PF3D7_0806000 AAA family ATPase, putative 14 0.29 1.5E-09PF3D7_1312900 eukaryotic translation initation factor 4 gamma, putative GO-0016070-RNA metabolic process 15 0.28 3.1E-09PF3D7_1247300 conserved protein, unknown function GO-0006506-GPI anchor biosynthetic process 16 0.28 3.7E-09PF3D7_0202000 knob-associated histidine-rich protein 17 0.28 5.0E-09PF3D7_0912500 conserved Plasmodium protein, unknown function GO-0006355-regulation of transcription DNA-dependent 18 0.28 5.5E-09PF3D7_0624800 conserved Plasmodium protein, unknown function 19 0.28 1.2E-08PF3D7_0511100 conserved Plasmodium protein, unknown function 20 0.28 8.8E-09PF3D7_0411000 conserved Plasmodium protein, unknown function 21 0.28 9.7E-09PF3D7_0614300 organic anion transporter 22 0.27 1.3E-08PF3D7_0805000 alpha/beta hydrolase, putative 23 0.27 1.9E-08PF3D7_1129800 conserved Plasmodium protein, unknown function 24 0.27 1.9E-08PF3D7_1242600 protein geranylgeranyltransferase type II, alpha subunit, putative 25 0.27 1.9E-08

PF3D7_1030600 glycoprotease, putative GO-0006508-proteolysis 26 0.27 2.5E-08PF3D7_0217700 E2F-associated phosphoprotein, putative 27 0.26 6.2E-08PF3D7_1464700 ATP synthase (C/AC39) subunit, putative 28 0.26 5.0E-08PF3D7_0201900 erythrocyte membrane protein 3 29 0.26 5.5E-08PF3D7_1432100 voltage-dependent anion-selective channel protein, putative 30 0.26 6.2E-08PF3D7_0715000 4-nitrophenylphosphatase GO-0008152-metabolic process 31 0.26 7.0E-08PF3D7_1462900 conserved Plasmodium protein, unknown function 32 0.26 7.6E-08PF3D7_0724200 type 2A phosphatase-associated protein 42, putative GO-0007165-signal transduction 33 0.26 9.1E-08PF3D7_1436000 glucose-6-phosphate isomerase GO-0006096-glycolysis 34 0.26 9.8E-08PF3D7_0629200 DnaJ protein, putative GO-0006457-protein folding 35 0.26 1.1E-07PF3D7_1408000 plasmepsin II 36 0.26 1.1E-07PF3D7_1107800 transcription factor with AP2 domain(s) GO-0006355-regulation of transcription DNA-dependent 37 0.26 1.1E-07PF3D7_1218600 arginine--tRNA ligase, putative GO-0006412-translation 38 0.25 1.4E-07PF3D7_1442800 conserved Plasmodium protein, unknown function GO-0006412-translation 39 0.25 1.9E-07PF3D7_1466400 transcription factor with AP2 domain(s) GO-0006355-regulation of transcription DNA-dependent 40 0.25 2.3E-07PF3D7_1223800 mitochondrial carrier protein, putative GO-0006810-transport 41 0.25 2.4E-07PF3D7_0411700 conserved Plasmodium protein, unknown function 42 0.25 4.9E-07PF3D7_1455100 protein phosphatase, putative GO-0006470-protein dephosphorylation 43 0.25 2.9E-07PF3D7_1246300 conserved Plasmodium protein, unknown function GO-0006886-intracellular protein transport 44 0.25 2.8E-07PF3D7_1429000 protein archease, putative 45 0.25 3.2E-07PF3D7_0622000 conserved Plasmodium protein, unknown function 46 0.25 3.2E-07PF3D7_1311200 alternative splicing regulator, putative 47 0.25 3.1E-07PF3D7_1130500 conserved Plasmodium protein, unknown function 48 0.25 3.4E-07PF3D7_0532200 Plasmodium exported protein (PHISTc), unknown function 49 0.25 3.9E-07PF3D7_0717400 queuine tRNA-ribosyltransferase, putative 50 0.24 5.2E-07PF3D7_0519600 zinc finger protein, putative 51 0.24 5.4E-07PF3D7_1035800 probable protein, unknown function 52 0.24 1.2E-06PF3D7_0603400 trophozoite exported protein 1 53 0.24 5.6E-07PF3D7_1022400 pre-mRNA splicing factor, putative GO-0008380-RNA splicing 54 0.24 6.2E-07PF3D7_0711500 regulator of chromosome condensation, putative GO-0007049-cell cycle 55 0.24 7.4E-07PF3D7_0529500 cell cycle regulator protein, putative GO-0051726-regulation of cell cycle 56 0.24 8.1E-07PF3D7_0813900 40S ribosomal protein S16, putative GO-0006412-translation 57 0.24 7.8E-07PF3D7_0109500 N-acetyltransferase, putative 58 0.24 9.0E-07PF3D7_1446200 M17 leucyl aminopeptidase GO-0006508-proteolysis 59 0.24 8.1E-07PF3D7_0717300 transcription initiation factor IIE, alpha subunit, putative 60 0.24 8.9E-07PF3D7_1323500 plasmepsin V GO-0006508-proteolysis 61 0.24 8.9E-07PF3D7_1401500 lysophospholipase, putative 62 0.24 9.5E-07PF3D7_1460400 ubiquitin carboxyl-terminal hydrolase isozyme L3 GO-0006511-ubiquitin-dependent protein catabolic process 63 0.24 1.1E-06PF3D7_0928600 conserved Plasmodium protein, unknown function 64 0.24 1.1E-06PF3D7_0912800 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 GO-0006351-transcription DNA-dependent 65 0.24 1.1E-06PF3D7_0713700 conserved Plasmodium protein, unknown function 66 0.24 1.1E-06PF3D7_1255200 erythrocyte membrane protein 1, PfEMP1 GO-0020033-antigenic variation 67 0.24 1.1E-06PF3D7_1408300 conserved Plasmodium protein, unknown function 68 0.24 1.9E-06PF3D7_0827900 protein disulfide isomerase ERp72 GO-0006457-protein folding 69 0.23 1.5E-06PF3D7_1464900 ATP-dependent zinc metalloprotease FTSH, putative GO-0006508-proteolysis 70 0.23 1.7E-06PF3D7_0723500 dynactin subunit 5, putative GO-0007018-microtubule-based movement 71 0.23 6.7E-06PF3D7_0526900 transmembrane emp24 domain-containing protein, putative GO-0016192-vesicle-mediated transport 72 0.23 3.0E-06PF3D7_0709300 Cg2 protein 73 0.23 2.0E-06PF3D7_1205900 conserved protein, unknown function 74 0.23 2.3E-06PF3D7_1408100 plasmepsin III | histo-aspartic protease GO-0006508-proteolysis 75 0.23 2.3E-06PF3D7_0619900 splicing factor 3A subunit 2, putative GO-0008380-RNA splicing 76 0.23 2.5E-06PF3D7_1357800 TCP-1/cpn60 chaperonin family, putative TCP1 GO-0006457-protein folding 77 0.23 2.5E-06PF3D7_1301700 Plasmodium exported protein (hyp8), unknown function 78 0.23 2.6E-06PF3D7_1473700 nucleoporin NUP116/NSP116, putative 79 0.23 2.9E-06

Table S2. List of genes significantly associated with artemisinin resistance (corrected p-value<0.01) and ranked by the strength of association wth parasite clearance half-life index (Correl. Coef.). Shown are the biological processes annoatated for each gene derived from the Gene Ontology (GO) database. Shaded in red are genes up-regulated in AR and blue are genes down-regulated in AR isolates.

Page 1 of 13


Correl. Coef.

corrected p-value

PF3D7_0527600 conserved Plasmodium protein, unknown function 80 0.23 2.7E-06PF3D7_1306600 vacuolar ATP synthase subunit h, putative GO-0015986-ATP synthesis coupled proton transport 81 0.23 2.7E-06PF3D7_1321400 palmitoyltransferase, putative 82 0.23 3.1E-06PF3D7_1340500 conserved Plasmodium protein, unknown function 83 0.23 2.9E-06PF3D7_0628700 conserved Plasmodium protein, unknown function 84 0.23 3.3E-06PF3D7_0507700 nuclear protein localization protein 4, putative GO-0010564-regulation of cell cycle process 85 0.23 3.3E-06PF3D7_0811400 conserved protein, unknown function 86 0.23 3.3E-06PF3D7_0823100 RWD domain-containing protein, putative 87 0.23 3.6E-06PF3D7_1419600 conserved Plasmodium protein, unknown function 88 0.23 3.8E-06PF3D7_0807800 proteasome subunit alpha type 5, putative 89 0.22 4.2E-06PF3D7_0218500 small nuclear ribonucleoprotein Sm D2, putative GO-0008380-RNA splicing 90 0.22 5.3E-06PF3D7_0527200 ubiquitin carboxyl-terminal hydrolase, putative GO-0006511-ubiquitin-dependent protein catabolic process 91 0.22 4.3E-06PF3D7_1204500 conserved Plasmodium protein, unknown function 92 0.22 5.0E-06PF3D7_0522800 G10 protein, putative 93 0.22 4.9E-06PF3D7_1130600 conserved Plasmodium protein, unknown function GO-0008033-tRNA processing 94 0.22 5.2E-06PF3D7_1466800 conserved Plasmodium protein, unknown function 95 0.22 5.5E-06PF3D7_0524900 tRNA-YW synthesizing protein, putative 96 0.22 5.5E-06PF3D7_1022500 citrate synthase, mitochondrial precursor, putative GO-0006099-tricarboxylic acid cycle 97 0.22 5.9E-06PF3D7_1352800 vacuolar fusion protein MON1, putative 98 0.22 6.0E-06PF3D7_0910100 Ran-binding protein, putative 99 0.22 6.1E-06PF3D7_1323400 60S ribosomal protein L23a, putative GO-0006412-translation 100 0.22 8.1E-06PF3D7_1424400 60S ribosomal protein L7-3, putative GO-0006412-translation 101 0.22 9.1E-06PF3D7_1467700 conserved Plasmodium protein, unknown function 102 0.22 9.0E-06PF3D7_0213000 conserved Plasmodium protein, unknown function 103 0.22 1.3E-05PF3D7_1437800 41-2 protein antigen precursor | transport protein particle (TRAPP) component, Bet3 104 0.22 1.8E-05

PF3D7_1422700 conserved Plasmodium protein, unknown function 105 0.22 9.7E-06PF3D7_0705000 methyltransferase, putative GO-0008152-metabolic process 106 0.22 1.0E-05PF3D7_1121700 protein GCN20 GO-0006810-transport 107 0.21 1.2E-05PF3D7_1402700 pre-mRNA splicing factor, putative GO-0006396-RNA processing 108 0.21 1.3E-05PF3D7_0110400 DNA-directed RNA polymerase 2, putative GO-0006355-regulation of transcription DNA-dependent 109 0.21 1.6E-05PF3D7_1476700 lysophospholipase, putative 110 0.21 1.8E-05PF3D7_1137100 mitochondrial ribosomal protein S9 precursor, putative GO-0006412-translation 111 0.21 1.5E-05PF3D7_1102500 Plasmodium exported protein (PHISTb), unknown function 112 0.21 1.6E-05PF3D7_0532300 Plasmodium exported protein (PHISTb), unknown function 113 0.21 2.0E-05PF3D7_1004100 hypothetical protein 114 0.21 1.9E-05PF3D7_1107700 pescadillo-like protein GO-0042254-ribosome biogenesis 115 0.21 1.9E-05PF3D7_1456900 conserved protein, unknown function 116 0.21 2.0E-05PF3D7_1438100 secretory complex protein 62 GO-0015031-protein transport 117 0.21 2.2E-05PF3D7_0923200 flavodoxin-like protein 118 0.21 2.1E-05PF3D7_1016100 conserved Plasmodium protein, unknown function 119 0.21 3.4E-05PF3D7_1351000 phosphatidylinositol transfer protein, putative GO-0006810-transport 120 0.21 2.3E-05PF3D7_0404300 conserved Plasmodium protein, unknown function 121 0.21 2.3E-05PF3D7_1317000 U4/U6.U5 tri-snRNP-associated protein 2, putative GO-0006511-ubiquitin-dependent protein catabolic process 122 0.21 2.3E-05PF3D7_0210000 secretory complex protein 61 gamma subunit 123 0.21 2.5E-05PF3D7_1238300 cell cycle control protein, putative GO-0016070-RNA metabolic process 124 0.21 2.5E-05PF3D7_0309300 N2227-like protein, putative 125 0.21 2.6E-05PF3D7_0719300 actin-related protein, putative 126 0.21 2.6E-05PF3D7_0410000 conserved Plasmodium protein, unknown function GO-0006397-mRNA processing 127 0.21 2.6E-05PF3D7_1318000 conserved Plasmodium membrane protein, unknown function 128 0.21 2.8E-05PF3D7_1468900 conserved Plasmodium protein, unknown function 129 0.21 2.8E-05PF3D7_1445100 histidine--tRNA ligase, putative GO-0006412-translation 130 0.21 2.8E-05PF3D7_1311900 vacuolar ATP synthase subunit a GO-0015986-ATP synthesis coupled proton transport 131 0.21 2.8E-05PF3D7_1003700 conserved Plasmodium protein, unknown function GO-0006281-DNA repair 132 0.21 2.9E-05PF3D7_0720500 conserved Plasmodium protein, unknown function 133 0.21 3.2E-05PF3D7_1401600 Plasmodium exported protein (PHISTb), unknown function 134 0.20 3.1E-05PF3D7_1326400 translation initiation factor EIF-2B gamma subunit, putative 135 0.20 3.1E-05PF3D7_1206700 eukaryotic translation initiation factor 5, putative GO-0006413-translational initiation 136 0.20 3.2E-05PF3D7_1401300 aminopeptidase, putative 137 0.20 3.4E-05PF3D7_0825300 conserved protein, unknown function 138 0.20 3.8E-05PF3D7_0215200 conserved Plasmodium protein, unknown function 139 0.20 4.0E-05PF3D7_0213800 conserved Plasmodium protein, unknown function 140 0.20 4.1E-05PF3D7_0302100 serine/threonine protein kinase GO-0006468-protein phosphorylation 141 0.20 3.9E-05PF3D7_0716700 conserved Plasmodium protein, unknown function 142 0.20 3.9E-05PF3D7_0725300 conserved Plasmodium protein, unknown function 143 0.20 3.9E-05PF3D7_1247200 conserved Plasmodium protein, unknown function 144 0.20 4.2E-05PF3D7_0109600 cold-shock protein, putative GO-0006355-regulation of transcription DNA-dependent 145 0.20 5.1E-05PF3D7_0522900 zinc finger protein, putative 146 0.20 4.2E-05PF3D7_1203000 origin recognition complex subunit 1 GO-0006270-DNA-dependent DNA replication initiation 147 0.20 4.6E-05PF3D7_0505800 small ubiquitin-related modifier 148 0.20 4.7E-05PF3D7_0717500 calcium-dependent protein kinase 4 GO-0006468-protein phosphorylation 149 0.20 4.7E-05PF3D7_1340600 RNA lariat debranching enzyme, putative 150 0.20 4.7E-05PF3D7_1410100 alpha/beta hydrolase, putative 151 0.20 1.2E-04PF3D7_1251000 conserved Plasmodium protein, unknown function 152 0.20 7.0E-05PF3D7_0201800 knob associated heat shock protein 40 GO-0006457-protein folding 153 0.20 5.2E-05PF3D7_0731300 Plasmodium exported protein (PHISTb), unknown function 154 0.20 5.1E-05PF3D7_0303000 N-ethylmaleimide-sensitive fusion protein GO-0006888-ER to Golgi vesicle-mediated transport 155 0.20 5.4E-05PF3D7_0519900 conserved Plasmodium protein, unknown function 156 0.20 5.9E-05PF3D7_0306800 T-complex protein beta subunit, putative TCP1-b GO-0006457-protein folding 157 0.20 6.8E-05PF3D7_0109800 phenylalanine--tRNA ligase, putative GO-0006412-translation 158 0.20 7.2E-05PF3D7_0211700 tyrosine kinase-like protein, putative GO-0006468-protein phosphorylation 159 0.20 7.6E-05PF3D7_0915500 conserved Plasmodium protein, unknown function 160 0.19 9.5E-05PF3D7_1309100 60S ribosomal protein L24, putative GO-0006412-translation 161 0.19 8.5E-05PF3D7_0632400 rifin | PIR protein GO-0020033-antigenic variation 162 0.19 3.2E-04

Page 2 of 13


Correl. Coef.

corrected p-value

PF3D7_1119500 clathrin coat assembly protein, putative GO-0006886-intracellular protein transport 163 0.19 9.5E-05PF3D7_1251500 DEAD/DEAH box ATP-dependent RNA helicase, putative GO-0016070-RNA metabolic process 164 0.19 1.0E-04PF3D7_1239300 conserved Plasmodium protein, unknown function 165 0.19 1.0E-04PF3D7_0505900 conserved Plasmodium protein, unknown function GO-0006457-protein folding 166 0.19 1.2E-04PF3D7_0806100 conserved Plasmodium protein, unknown function 167 0.19 1.7E-04PF3D7_1472900 dihydroorotase, putative 168 0.19 1.1E-04PF3D7_1204400 conserved Plasmodium membrane protein, unknown function 169 0.19 3.5E-04PF3D7_0621800 nascent polypeptide associated complex alpha chain, putative 170 0.19 1.2E-04PF3D7_0406000 conserved Plasmodium protein, unknown function 171 0.19 1.3E-04PF3D7_0724300 3-demethylubiquinone-9 3-methyltransferase, putative 172 0.19 1.5E-04PF3D7_1473100 GTPase-activating protein, putative GO-0032313-regulation of Rab GTPase activity 173 0.19 1.3E-04PF3D7_1446900 glutaminyl-peptide cyclotransferase, putative 174 0.19 1.3E-04PF3D7_1343200 tRNA guanosine-2'-O-methyltransferase, putative 175 0.19 1.4E-04PF3D7_0721800 conserved Plasmodium protein, unknown function 176 0.19 1.5E-04PF3D7_0214200 mitochondrial ribosomal protein L13 precursor, putative GO-0006412-translation 177 0.19 1.6E-04PF3D7_0622200 radical SAM protein, putative 178 0.19 1.7E-04PF3D7_1327000 conserved Plasmodium protein, unknown function 179 0.19 1.6E-04PF3D7_1028100 protoporphyrinogen oxidase GO-0055114-oxidation-reduction process 180 0.19 1.6E-04PF3D7_0214300 conserved Plasmodium protein, unknown function 181 0.19 1.6E-04PF3D7_1411300 conserved Plasmodium protein, unknown function GO-0006457-protein folding 182 0.19 1.7E-04PF3D7_1366900 conserved Plasmodium protein, unknown function GO-0006413-translational initiation 183 0.19 1.7E-04PF3D7_1205400 conserved Plasmodium protein, unknown function 184 0.19 1.7E-04PF3D7_1218700 conserved Plasmodium protein, unknown function 185 0.19 1.9E-04PF3D7_0830700 Plasmodium exported protein (hyp9), unknown function 186 0.19 2.7E-04PF3D7_1372100 Plasmodium exported protein (PHISTb), unknown function 187 0.18 2.3E-04PF3D7_1212100 peripheral plastid protein 1, putative GO-0006412-translation 188 0.18 2.1E-04PF3D7_1206800 conserved Plasmodium protein, unknown function 189 0.18 2.3E-04PF3D7_0532500 Plasmodium exported protein, unknown function 190 0.18 2.2E-04PF3D7_1443300 U6 snRNA-associated Sm-like protein LSm5, putative GO-0008380-RNA splicing 191 0.18 2.3E-04PF3D7_1444700 conserved Plasmodium protein, unknown function 192 0.18 9.2E-04PF3D7_0936100 early transcribed membrane protein 193 0.18 2.4E-04PF3D7_0812400 karyopherin alpha GO-0006913-nucleocytoplasmic transport 194 0.18 2.4E-04PF3D7_0614400 conserved protein, unknown function GO-0006397-mRNA processing 195 0.18 2.7E-04PF3D7_1472800 conserved Plasmodium protein, unknown function 196 0.18 2.6E-04PF3D7_1127300 methyltransferase, putative 197 0.18 2.8E-04PF3D7_1243100 zinc finger protein, putative 198 0.18 2.8E-04PF3D7_1323200 vacuolar ATP synthase subunit g, putative 199 0.18 2.8E-04PF3D7_1467600 conserved Plasmodium protein, unknown function GO-0006817-phosphate ion transport 200 0.18 2.8E-04PF3D7_1402800 conserved Plasmodium protein, unknown function 201 0.18 2.8E-04PF3D7_1305700 conserved Plasmodium protein, unknown function 202 0.18 2.9E-04PF3D7_1317200 transcription factor with AP2 domain(s) GO-0006355-regulation of transcription DNA-dependent 203 0.18 2.9E-04PF3D7_1477500 Plasmodium exported protein (PHISTb), unknown function 204 0.18 2.9E-04PF3D7_1458500 conserved Plasmodium protein, unknown function 205 0.18 3.0E-04PF3D7_0724000 Rab GTPase activator and protein kinase, putative GO-0006468-protein phosphorylation 206 0.18 3.0E-04PF3D7_0114000 exported protein family 1 207 0.18 3.0E-04PF3D7_0509700 conserved Plasmodium protein, unknown function 208 0.18 3.7E-04PF3D7_1337200 1-deoxy-D-xylulose 5-phosphate synthase GO-0008152-metabolic process 209 0.18 3.0E-04PF3D7_1252200 chitinase GO-0005975-carbohydrate metabolic process 210 0.18 3.0E-04PF3D7_1337300 exoribonuclease, putative 211 0.18 3.2E-04PF3D7_1033200 early transcribed membrane protein 10.2 212 0.18 3.3E-04PF3D7_0316500 conserved Plasmodium protein, unknown function GO-0007049-cell cycle 213 0.18 3.3E-04PF3D7_1130700 structural maintenance of chromosome protein, putative GO-0051276-chromosome organization 214 0.18 3.3E-04PF3D7_1148700 Plasmodium exported protein (PHISTc), unknown function 215 0.18 3.7E-04PF3D7_1414600 RNA guanylyltransferase 216 0.18 3.4E-04PF3D7_0627900 conserved Plasmodium protein, unknown function GO-0006364-rRNA processing 217 0.18 3.8E-04PF3D7_0817300 asparagine-rich antigen 218 0.18 3.6E-04PF3D7_1457100 conserved Plasmodium protein, unknown function 219 0.18 3.8E-04PF3D7_0622300 vacuolar transporter chaperone, putative 220 0.18 4.0E-04PF3D7_0418700 RNA-binding protein NOB1, putative 221 0.18 3.9E-04PF3D7_1028000 methyltransferase, putative GO-0008152-metabolic process 222 0.18 4.0E-04PF3D7_1363400 polyubiquitin binding protein, putative 223 0.18 4.0E-04PF3D7_1214800 conserved Plasmodium protein, unknown function 224 0.18 8.6E-04PF3D7_0516200 40S ribosomal protein S14, putative GO-0006412-translation 225 0.18 4.6E-04PF3D7_1031100 conserved Plasmodium protein, unknown function 226 0.18 4.3E-04PF3D7_1108000 IWS1-like protein, putative 227 0.18 4.5E-04PF3D7_0404600 conserved Plasmodium membrane protein, unknown function GO-0006817-phosphate ion transport 228 0.18 4.5E-04PF3D7_1114900 conserved Plasmodium protein, unknown function 229 0.18 4.5E-04PF3D7_1402300 26S proteasome regulatory subunit GO-0006508-proteolysis 230 0.17 4.6E-04PF3D7_1129000 spermidine synthase 231 0.17 4.7E-04PF3D7_1340100 exosome complex component RRP42, putative GO-0006396-RNA processing 232 0.17 5.4E-04PF3D7_0804900 GTPase-activating protein, putative 233 0.17 4.9E-04PF3D7_0624000 hexokinase GO-0006096-glycolysis 234 0.17 4.9E-04PF3D7_0422400 40S ribosomal protein S19, putative GO-0006412-translation 235 0.17 5.3E-04PF3D7_1421400 DNA-directed RNA polymerase III subunit C, putative GO-0006355-regulation of transcription DNA-dependent 236 0.17 5.5E-04PF3D7_0628000 6-pyruvoyltetrahydropterin synthase 237 0.17 7.9E-04PF3D7_1126400 large ribosomal subunit processing factor, putative 238 0.17 1.2E-03PF3D7_0500500 rifin | PIR protein GO-0020033-antigenic variation 239 0.17 8.7E-04PF3D7_0827800 SET domain protein, putative 240 0.17 5.6E-04PF3D7_1133700 conserved Plasmodium protein, unknown function 241 0.17 5.9E-04PF3D7_1320200 TBC domain protein, putative GO-0032313-regulation of Rab GTPase activity 242 0.17 6.0E-04PF3D7_1241200 conserved Plasmodium protein, unknown function 243 0.17 6.1E-04PF3D7_1115200 SET domain protein, putative 244 0.17 6.3E-04PF3D7_1034000 Sec1 family protein, putative GO-0016192-vesicle-mediated transport 245 0.17 6.4E-04

Page 3 of 13


Correl. Coef.

corrected p-value

PF3D7_1203100 conserved Plasmodium protein, unknown function 246 0.17 6.9E-04PF3D7_1301400 Plasmodium exported protein (hyp12), unknown function 247 0.17 7.4E-04PF3D7_0410500 conserved Plasmodium protein, unknown function 248 0.17 9.4E-04PF3D7_0916100 thioredoxin 3 GO-0045454-cell redox homeostasis 249 0.17 8.7E-04PF3D7_1448000 U3 snoRNA-associated small subunit rRNA processing protein 250 0.17 7.0E-04PF3D7_0307800 conserved Plasmodium protein, unknown function GO-0006810-transport 251 0.17 7.1E-04PF3D7_1333800 conserved Plasmodium protein, unknown function 252 0.17 1.0E-03PF3D7_0404400 6-cysteine protein 253 0.17 8.4E-04PF3D7_1133600 conserved Plasmodium protein, unknown function 254 0.17 7.9E-04PF3D7_0423700 early transcribed membrane protein 4 255 0.17 8.2E-04PF3D7_1317800 40S ribosomal protein S15/S19, putative GO-0006412-translation 256 0.17 8.7E-04PF3D7_0608500 proteasome subunit alpha type 2, putative GO-0006511-ubiquitin-dependent protein catabolic process 257 0.17 8.5E-04PF3D7_0609200 citrate synthase-like protein, putative 258 0.17 8.2E-04PF3D7_1468200 conserved protein, unknown function 259 0.17 8.3E-04PF3D7_1471200 inorganic anion exchanger, inorganic anion antiporter 260 0.17 8.3E-04PF3D7_1106700 dna2/nam7 helicase family member, putative 261 0.17 8.7E-04PF3D7_1142300 conserved Plasmodium membrane protein, unknown function GO-0009405-pathogenesis 262 0.17 8.7E-04PF3D7_1317700 conserved Plasmodium protein, unknown function 263 0.17 8.9E-04PF3D7_1219000 formin 2 264 0.17 8.9E-04PF3D7_0215100 RING zinc finger protein, putative 265 0.17 9.2E-04PF3D7_0626100 oxidoreductase, short-chain dehydrogenase family, putative GO-0008152-metabolic process 266 0.17 9.1E-04PF3D7_1431700 60S ribosomal protein L14, putative GO-0006412-translation 267 0.17 9.3E-04PF3D7_0621200 pyridoxine biosynthesis protein PDX1 268 0.17 9.5E-04PF3D7_1231800 asparagine-rich protein, putative 269 0.17 9.6E-04PF3D7_1205700 targeted glyoxalase II 270 0.17 9.7E-04PF3D7_1148900 probable protein, unknown function 271 0.17 9.7E-04PF3D7_0905900 beta subunit of coatomer complex, putative GO-0006886-intracellular protein transport 272 0.17 1.0E-03PF3D7_0719200 NIMA related kinase 4 GO-0006468-protein phosphorylation 273 0.17 1.2E-03PF3D7_1105900 conserved Plasmodium membrane protein, unknown function GO-0006810-transport 274 0.17 1.0E-03PF3D7_0307100 40S ribosomal protein S12, putative GO-0006412-translation 275 0.17 1.7E-03PF3D7_0518000 conserved protein, unknown function 276 0.16 1.1E-03PF3D7_0923400 conserved Plasmodium protein, unknown function 277 0.16 1.2E-03PF3D7_1003500 40S ribosomal protein S20e, putative GO-0006412-translation 278 0.16 1.1E-03PF3D7_0416800 small GTP-binding protein sar1 GO-0006886-intracellular protein transport 279 0.16 1.1E-03PF3D7_0407200 peptidyl-tRNA hydrolase 2, putative GO-0006412-translation 280 0.16 1.1E-03PF3D7_1354700 conserved Plasmodium protein, unknown function GO-0006412-translation 281 0.16 1.2E-03PF3D7_0605100 RNA-binding protein, putative 282 0.16 1.1E-03PF3D7_0820200 phosphatidylglycerophosphate synthase 283 0.16 1.2E-03PF3D7_0107900 conserved Plasmodium protein, unknown function 284 0.16 1.2E-03PF3D7_1307100 U3 small nucleolar RNA-associated protein 6, putative 285 0.16 1.2E-03PF3D7_0723600 conserved Plasmodium protein, unknown function 286 0.16 1.2E-03PF3D7_0114500 Plasmodium exported protein (hyp10), unknown function 287 0.16 1.3E-03PF3D7_1370300 membrane associated histidine-rich protein 288 0.16 1.4E-03PF3D7_0524300 conserved Plasmodium protein, unknown function 289 0.16 1.3E-03PF3D7_0320100 SNARE protein GO-0006886-intracellular protein transport 290 0.16 1.5E-03PF3D7_1436900 histidine triad protein, putative 291 0.16 1.4E-03PF3D7_1142200 conserved Plasmodium protein, unknown function 292 0.16 1.4E-03PF3D7_0512000 prefoldin subunit, putative GO-0006457-protein folding 293 0.16 1.4E-03PF3D7_0603600 conserved Plasmodium protein, unknown function GO-0006355-regulation of transcription DNA-dependent 294 0.16 1.4E-03PF3D7_1136800 DnaJ protein, putative GO-0006457-protein folding 295 0.16 1.5E-03PF3D7_1341900 vacuolar ATP synthase subunit d, putative GO-0015986-ATP synthesis coupled proton transport 296 0.16 2.1E-03PF3D7_1329200 conserved Plasmodium protein, unknown function 297 0.16 1.5E-03PF3D7_1476100 early transcribed membrane protein 14.2 298 0.16 1.6E-03PF3D7_0619100 conserved Plasmodium protein, unknown function GO-0006281-DNA repair 299 0.16 1.5E-03PF3D7_0108800 conserved Plasmodium protein, unknown function GO-0006810-transport 300 0.16 2.2E-03PF3D7_1144000 40S ribosomal protein S21e, putative GO-0006412-translation 301 0.16 1.5E-03PF3D7_1116300 peptidyl-prolyl cis-trans isomerase GO-0006457-protein folding 302 0.16 1.5E-03PF3D7_0903900 60S ribosomal protein L32, putative GO-0006412-translation 303 0.16 1.5E-03PF3D7_1313900 conserved Plasmodium protein, unknown function 304 0.16 1.5E-03PF3D7_0806500 DnaJ protein, putative GO-0006457-protein folding 305 0.16 1.6E-03PF3D7_1429500 diphthamide synthesis protein, putative 306 0.16 1.7E-03PF3D7_1359500 conserved Plasmodium protein, unknown function 307 0.16 1.8E-03PF3D7_0928300 conserved Plasmodium protein, unknown function 308 0.16 2.1E-03PF3D7_0723000 tRNAHis guanylyltransferase, putative 309 0.16 1.7E-03PF3D7_0523000 multidrug resistance protein GO-0006810-transport 310 0.16 1.7E-03PF3D7_1320300 conserved Plasmodium protein, unknown function GO-0006508-proteolysis 311 0.16 1.9E-03PF3D7_0626000 conserved Plasmodium protein, unknown function 312 0.16 1.8E-03PF3D7_1206000 shewanella-like protein phosphatase 2 313 0.16 3.1E-03PF3D7_0305800 P-loop containing nucleoside triphosphate hydrolase, putative GO-0008152-metabolic process 314 0.16 2.2E-03PF3D7_1433300 chromatin assembly factor 1 P55 subunit, putative GO-0006334-nucleosome assembly 315 0.16 1.8E-03PF3D7_0512400 conserved Plasmodium protein, unknown function 316 0.16 1.9E-03PF3D7_1126900 small nuclear ribonucleoprotein F, putative 317 0.16 1.8E-03PF3D7_1135000 conserved Plasmodium protein, unknown function 318 0.16 2.2E-03PF3D7_1423000 GTPase, putative 319 0.16 1.9E-03PF3D7_1316800 protein transport protein SEC20, putative 320 0.16 2.1E-03PF3D7_0905200 mitochondrial carrier protein, putative GO-0006810-transport 321 0.16 2.0E-03PF3D7_0404500 6-cysteine protein GO-0016255-attachment of GPI anchor to protein 322 0.16 2.0E-03PF3D7_1413900 DnaJ protein, putative GO-0006457-protein folding 323 0.16 2.0E-03PF3D7_1438000 eukaryotic translation initiation factor eIF2A, putative 324 0.16 2.1E-03PF3D7_1012600 GMP synthetase 325 0.16 2.1E-03PF3D7_0413400 erythrocyte membrane protein 1 (PfEMP1), exon 1, pseudogene GO-0009405-pathogenesis 326 0.16 2.1E-03PF3D7_0618300 60S ribosomal protein L27a, putative GO-0006412-translation 327 0.16 2.2E-03PF3D7_1353600 ER lumen protein retaining receptor 328 0.16 2.2E-03

Page 4 of 13


Correl. Coef.

corrected p-value

PF3D7_1038800 RESA-like protein with PHIST and DnaJ domains GO-0006457-protein folding 329 0.16 2.2E-03PF3D7_1326900 conserved Plasmodium membrane protein, unknown function 330 0.15 2.3E-03PF3D7_1022200 conserved Plasmodium membrane protein, unknown function 331 0.15 2.3E-03PF3D7_0319500 RNA-binding protein, putative 332 0.15 2.3E-03PF3D7_0405300 sequestrin | liver specific protein 2, putative GO-0020035-cytoadherence to microvasculature mediated by symbiont

protein333 0.15 2.3E-03

PF3D7_1344100 krox-like protein, putative 334 0.15 2.3E-03PF3D7_1011700 DNA repair protein RAD23, putative 335 0.15 2.3E-03PF3D7_0702500 Plasmodium exported protein, unknown function 336 0.15 2.5E-03PF3D7_0312300 26S proteasome regulatory subunit S14, putative GO-0006511-ubiquitin-dependent protein catabolic process 337 0.15 2.5E-03PF3D7_1447700 conserved Plasmodium protein, unknown function 338 0.15 2.6E-03PF3D7_1344800 aspartate carbamoyltransferase 339 0.15 2.5E-03PF3D7_1472000 pre-mRNA-splicing factor ISY1, putative 340 0.15 2.5E-03PF3D7_0519400 40S ribosomal protein S24, putative GO-0006412-translation 341 0.15 2.6E-03PF3D7_0822700 conserved Plasmodium protein, unknown function 342 0.15 2.6E-03PF3D7_1235900 pre-mRNA-splicing factor SYF1, putative GO-0006396-RNA processing 343 0.15 2.7E-03PF3D7_1353100 Plasmodium exported protein, unknown function 344 0.15 2.8E-03PF3D7_1421600 conserved Plasmodium protein, unknown function 345 0.15 2.7E-03PF3D7_1452400 conserved Plasmodium protein, unknown function 346 0.15 2.8E-03PF3D7_1207900 conserved Plasmodium protein, unknown function 347 0.15 2.8E-03PF3D7_0815600 eukaryotic translation initiation factor, putative GO-0006412-translation 348 0.15 2.8E-03PF3D7_1133500 conserved Plasmodium protein, unknown function 349 0.15 2.8E-03PF3D7_1323800 vacuolar protein sorting-associated protein 52, putative 350 0.15 2.9E-03PF3D7_0601900 conserved Plasmodium protein, unknown function GO-0015031-protein transport 351 0.15 3.3E-03PF3D7_0501200 parasite-infected erythrocyte surface protein 352 0.15 3.0E-03PF3D7_1104200 chromatin remodeling protein GO-0006355-regulation of transcription DNA-dependent 353 0.15 3.1E-03PF3D7_0823700 conserved Plasmodium protein, unknown function 354 0.15 3.3E-03PF3D7_1253100 Plasmodium exported protein (PHISTa), unknown function 355 0.15 3.1E-03PF3D7_0931900 adenylate kinase-like protein 2 356 0.15 3.2E-03PF3D7_0927900 phosphatidylserine decarboxylase 357 0.15 3.5E-03PF3D7_0936400 ring-exported protein 4 358 0.15 3.3E-03PF3D7_1305300 conserved Plasmodium protein, unknown function 359 0.15 3.2E-03PF3D7_1477600 surface-associated interspersed protein 14.1 (SURFIN 14.1) 360 0.15 3.2E-03PF3D7_1220100 pre-mRNA splicing factor, putative GO-0000375-RNA splicing via transesterification reactions 361 0.15 3.2E-03PF3D7_1124200 conserved Plasmodium protein, unknown function 362 0.15 3.3E-03PF3D7_1117500 tyrosine--tRNA ligase GO-0006412-translation 363 0.15 3.3E-03PF3D7_1003800 U5 small nuclear ribonuclear protein, putative GO-0000375-RNA splicing via transesterification reactions 364 0.15 3.3E-03PF3D7_0523500 outer arm dynein lc3, putative 365 0.15 3.5E-03PF3D7_0212300 peptide chain release factor subunit 1, putative 366 0.15 3.3E-03PF3D7_0500900 serine/threonine protein kinase, FIKK family GO-0006468-protein phosphorylation 367 0.15 3.4E-03PF3D7_1334200 chaperone binding protein, putative GO-0006457-protein folding 368 0.15 3.4E-03PF3D7_1320900 RNA-binding protein, putative GO-0006457-protein folding 369 0.15 3.5E-03PF3D7_1116200 pyridoxine biosynthesis protein PDX2 370 0.15 3.4E-03PF3D7_1429400 rRNA (adenosine-2'-O-)-methyltransferase, putative GO-0006396-RNA processing 371 0.15 3.5E-03PF3D7_0412400 erythrocyte membrane protein 1, PfEMP1 GO-0020033-antigenic variation 372 0.15 3.5E-03PF3D7_1212500 glycerol-3-phosphate acyltransferase GO-0008152-metabolic process 373 0.15 3.5E-03PF3D7_1349200 glutamate--tRNA ligase, putative GO-0006412-translation 374 0.15 3.6E-03PF3D7_1478600 EMP1-trafficking protein 375 0.15 3.6E-03PF3D7_1235500 mRNA methyltransferase, putative GO-0006139-nucleobase-containing compound metabolic process 376 0.15 3.6E-03

PF3D7_0906910 tubulin-specific chaperone, putative 377 0.15 3.6E-03PF3D7_1420400 glycine--tRNA ligase GO-0006412-translation 378 0.15 3.8E-03PF3D7_0406200 sexual stage-specific protein precursor 379 0.15 3.8E-03PF3D7_1139300 transcription factor with AP2 domain(s) GO-0006355-regulation of transcription DNA-dependent 380 0.15 3.9E-03PF3D7_0304400 60S ribosomal protein L44, putative GO-0006412-translation 381 0.15 4.0E-03PF3D7_1360200 conserved protein, unknown function 382 0.15 3.9E-03PF3D7_1108600 endoplasmic reticulum-resident calcium binding protein ERC GO-0006886-intracellular protein transport 383 0.15 3.9E-03PF3D7_1126200 40S ribosomal protein S18, putative GO-0006412-translation 384 0.15 4.0E-03PF3D7_1005400 conserved Plasmodium protein, unknown function 385 0.15 4.4E-03PF3D7_0526700 conserved Plasmodium protein, unknown function 386 0.15 4.0E-03PF3D7_0215500 conserved Plasmodium protein, unknown function 387 0.15 4.1E-03PF3D7_0917900 heat shock protein 70 BiP 388 0.15 4.1E-03PF3D7_0220300 Plasmodium exported protein, unknown function 389 0.15 4.7E-03PF3D7_1034200 apicoplast ribosomal protein L27 precursor, putative GO-0006412-translation 390 0.15 4.4E-03PF3D7_1423100 ankyrin, putative 391 0.15 4.2E-03PF3D7_0219100 conserved protein, unknown function 392 0.15 4.2E-03PF3D7_0601700 Plasmodium exported protein (PHISTa), unknown function, pseudogene 393 0.15 5.0E-03PF3D7_0213700 conserved protein, unknown function 394 0.15 4.5E-03PF3D7_0304600 circumsporozoite (CS) protein GO-0016255-attachment of GPI anchor to protein 395 0.15 4.4E-03PF3D7_0936700 lysophospholipase, putative 396 0.15 4.4E-03PF3D7_1309600 ribosomal RNA methyltransferase, putative GO-0006364-rRNA processing 397 0.14 4.6E-03PF3D7_0729400 ribosome biogenesis protein BRX1 homolog, putative 398 0.14 4.6E-03PF3D7_1469100 conserved Plasmodium protein, unknown function 399 0.14 4.7E-03PF3D7_1143400 translation initiation factor eIF-1A, putative GO-0006413-translational initiation 400 0.14 4.7E-03PF3D7_1417600 conserved Plasmodium protein, unknown function 401 0.14 4.8E-03PF3D7_1037200 conserved Plasmodium protein, unknown function 402 0.14 5.1E-03PF3D7_0730200 adapter-related protein, putative GO-0006886-intracellular protein transport 403 0.14 5.0E-03PF3D7_1476000 conserved Plasmodium protein, unknown function 404 0.14 5.1E-03PF3D7_1219700 raf kinase inhibitor 405 0.14 8.1E-03PF3D7_0818400 nucleolar preribosomal assembly protein, putative 406 0.14 5.1E-03PF3D7_1310800 conserved Plasmodium protein, unknown function 407 0.14 5.1E-03PF3D7_0702900 centrin, putative 408 0.14 5.2E-03PF3D7_0628600 conserved Plasmodium protein, unknown function GO-0006355-regulation of transcription DNA-dependent 409 0.14 5.2E-03PF3D7_1033400 haloacid dehalogenase-like hydrolase, putative GO-0008152-metabolic process 410 0.14 5.2E-03

Page 5 of 13


Correl. Coef.

corrected p-value

PF3D7_1460700 60S ribosomal protein L27, putative GO-0006412-translation 411 0.14 5.3E-03PF3D7_1004400 RNA-binding protein, putative 412 0.14 5.3E-03PF3D7_0523400 DnaJ protein, putative GO-0006457-protein folding 413 0.14 5.3E-03PF3D7_1333400 conserved protein, unknown function 414 0.14 6.7E-03PF3D7_0204800 3'-5' exonuclease, putative GO-0006139-nucleobase-containing compound metabolic process 415 0.14 5.4E-03

PF3D7_0110200 FAD-linked sulfhydryl oxidase ERV1, putative GO-0055114-oxidation-reduction process 416 0.14 5.5E-03PF3D7_0212000 GDP-fructose 417 0.14 5.5E-03PF3D7_0408300 zinc finger, RAN binding protein, putative 418 0.14 5.5E-03PF3D7_1332400 nucleotidyltransferase, putative 419 0.14 5.5E-03PF3D7_0209300 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 420 0.14 6.2E-03PF3D7_0102600 serine/threonine protein kinase, FIKK family GO-0006468-protein phosphorylation 421 0.14 5.6E-03PF3D7_1307700 conserved Plasmodium protein, unknown function GO-0006886-intracellular protein transport 422 0.14 5.6E-03PF3D7_1426200 arginine methyltransferase 1 GO-0006396-RNA processing 423 0.14 5.8E-03PF3D7_0924200 conserved Plasmodium protein, unknown function 424 0.14 5.8E-03PF3D7_0214700 conserved Plasmodium protein, unknown function 426 0.14 6.2E-03PF3D7_1476400 serine/threonine protein kinase, FIKK family, pseudogene GO-0006468-protein phosphorylation 427 0.14 6.0E-03PF3D7_1465900 40S ribosomal protein S3, putative GO-0006412-translation 428 0.14 6.0E-03PF3D7_0526800 conserved Plasmodium protein, unknown function 430 0.14 6.2E-03PF3D7_0518300 proteasome subunit beta type 1, putative GO-0006511-ubiquitin-dependent protein catabolic process 431 0.14 6.2E-03PF3D7_1109900 apicoplast ribosomal protein L36e precursor, putative GO-0006412-translation 432 0.14 6.2E-03PF3D7_0720700 phosphoinositide-binding protein, putative 433 0.14 6.3E-03PF3D7_1017400 phosphomannomutase, putative 434 0.14 6.5E-03PF3D7_0623900 ribonuclease H2 subunit A, putative 435 0.14 6.5E-03PF3D7_0718500 prefoldin subunit 3, putative Prefoldin 436 0.14 6.5E-03

PF3D7_1244200 transcription factor Tfb2, putative GO-0006355-regulation of transcription DNA-dependent 437 0.14 6.5E-03PF3D7_1369500 conserved Plasmodium protein, unknown function 438 0.14 6.5E-03PF3D7_1218800 secreted ookinete protein, putative 439 0.14 6.7E-03PF3D7_1233400 conserved Plasmodium membrane protein, unknown function 440 0.14 6.7E-03PF3D7_0406400 cytosolic glyoxalase II 441 0.14 6.7E-03PF3D7_0509300 conserved Plasmodium protein, unknown function 442 0.14 7.6E-03PF3D7_1004300 zinc finger, C3HC4 type, putative 443 0.14 6.8E-03PF3D7_1130100 60S ribosomal protein L38e, putative GO-0006412-translation 444 0.14 7.9E-03PF3D7_1222000 conserved protein, unknown function 445 0.14 6.8E-03PF3D7_1457600 conserved Plasmodium protein, unknown function 446 0.14 6.9E-03PF3D7_0301700 Plasmodium exported protein, unknown function 447 0.14 7.0E-03PF3D7_1026200 conserved Plasmodium protein, unknown function 448 0.14 7.2E-03PF3D7_0403700 CGI-201 protein, short form GO-0006396-RNA processing 449 0.14 7.2E-03PF3D7_1219600 aminophospholipid-transporting P-ATPase GO-0006754-ATP biosynthetic process 450 0.14 7.3E-03PF3D7_1428000 conserved Plasmodium membrane protein, unknown function 451 0.14 7.3E-03PF3D7_0703100 conserved Plasmodium protein, unknown function 452 0.14 8.9E-03PF3D7_0917000 conserved Plasmodium protein, unknown function 453 0.14 7.4E-03PF3D7_1419000 conserved Plasmodium protein, unknown function 454 0.14 7.6E-03PF3D7_0903400 DEAD/DEAH box helicase, putative 455 0.14 7.6E-03PF3D7_1451600 LCCL domain-containing protein 456 0.14 8.2E-03PF3D7_1242700 40S ribosomal protein S17, putative GO-0006412-translation 457 0.14 7.6E-03PF3D7_0405500 conserved Plasmodium protein, unknown function 458 0.14 7.9E-03PF3D7_0915400 6-phosphofructokinase GO-0006096-glycolysis 459 0.14 7.7E-03PF3D7_0409800 zinc finger protein, putative GO-0006355-regulation of transcription DNA-dependent 460 0.14 7.7E-03PF3D7_1403800 nuclear formin-like protein GO-0006412-translation 461 0.14 7.9E-03PF3D7_0708600 heat shock protein 86 family protein GO-0009408-response to heat 462 0.14 8.6E-03PF3D7_0423200 BSD-domain protein, putative 463 0.14 7.9E-03PF3D7_1011400 proteasome subunit beta type-5 GO-0006511-ubiquitin-dependent protein catabolic process 464 0.14 8.0E-03PF3D7_1142600 60S ribosomal protein L35ae, putative GO-0006412-translation 465 0.14 9.0E-03PF3D7_1366000 conserved Plasmodium protein, unknown function 466 0.14 8.4E-03PF3D7_1332500 SAM-dependent RNA methyltransferase, putative 467 0.14 8.4E-03PF3D7_1212700 eukaryotic translation initiation factor 3 subunit 10, putative 468 0.14 8.2E-03PF3D7_1473200 DnaJ protein, putative 469 0.14 8.3E-03PF3D7_1358500 zinc finger protein, putative 470 0.14 8.4E-03PF3D7_0511800 myo-inositol 1-phosphate synthase, putative GO-0008152-metabolic process 471 0.14 8.5E-03PF3D7_1362200 RuvB-like helicase 3 472 0.13 8.7E-03PF3D7_0607300 uroporphyrinogen III decarboxylase 473 0.13 8.7E-03PF3D7_1037600 DNA repair helicase RAD25, putative GO-0006281-DNA repair 475 0.13 8.8E-03PF3D7_1129900 transporter, putative 476 0.13 8.8E-03PF3D7_0624600 SNF2 helicase, putative 477 0.13 8.9E-03PF3D7_1424100 60S ribosomal protein L5, putative GO-0006412-translation 478 0.13 9.0E-03PF3D7_1208700 conserved Plasmodium protein, unknown function 479 0.13 9.0E-03PF3D7_0907900 peptide deformylase GO-0006412-translation 480 0.13 9.1E-03PF3D7_1443800 zinc finger protein, putative 481 0.13 9.1E-03PF3D7_1037700 enhancer of rudimentary homolog, putative 482 0.13 9.2E-03PF3D7_0403500 ubiquitin specific protease, putative GO-0006511-ubiquitin-dependent protein catabolic process 483 0.13 9.1E-03PF3D7_0913000 conserved Plasmodium protein, unknown function 484 0.13 9.6E-03PF3D7_1116400 ER membrane protein Sec12 GO-0006888-ER to Golgi vesicle-mediated transport 485 0.13 9.3E-03PF3D7_0917100 N-glycosylase/DNA lyase, putative 486 0.13 9.3E-03PF3D7_1328800 transcriptional regulatory protein sir2a GO-0006355-regulation of transcription DNA-dependent 487 0.13 9.7E-03PF3D7_1107200 conserved Plasmodium protein, unknown function 488 0.13 9.5E-03PF3D7_0502400 ring-stage membrane protein 1 | merozoite surface protein 8 492 0.13 9.7E-03PF3D7_0922500 phosphoglycerate kinase GO-0006096-glycolysis 493 0.13 9.8E-03PF3D7_0406600 conserved Plasmodium protein, unknown function GO-0006351-transcription DNA-dependent 4546 -0.13 1.0E-02PF3D7_1338700 conserved Plasmodium protein, unknown function 4548 -0.13 9.9E-03PF3D7_1441000 conserved Plasmodium protein, unknown function 4551 -0.13 9.7E-03PF3D7_0106300 calcium-transporting ATPase GO-0008152-metabolic process 4552 -0.13 9.7E-03PF3D7_1420900 mannose-1-phosphate guanyltransferase, putative 4553 -0.13 9.7E-03

Page 6 of 13


Correl. Coef.

corrected p-value

PF3D7_1012200 conserved Plasmodium protein, unknown function 4554 -0.13 9.7E-03PF3D7_1220300 cell cycle associated protein, putative GO-0007049-cell cycle 4555 -0.13 9.6E-03PF3D7_0809900 JmjC domain containing protein 4556 -0.13 9.5E-03PF3D7_0914000 pseudouridylate synthase, putative GO-0001522-pseudouridine synthesis 4557 -0.13 9.5E-03PF3D7_0935500 Plasmodium exported protein, unknown function 4558 -0.13 9.9E-03PF3D7_0513600 deoxyribodipyrimidine photo-lyase, putative GO-0006281-DNA repair 4559 -0.13 9.4E-03PF3D7_1204200 conserved Plasmodium protein, unknown function GO-0006633-fatty acid biosynthetic process 4560 -0.13 9.4E-03PF3D7_1336100 conserved Plasmodium protein, unknown function 4561 -0.13 9.4E-03PF3D7_1014100 conserved Plasmodium protein, unknown function 4562 -0.13 9.3E-03PF3D7_1104100 syntaxin, Qa-SNARE family GO-0006886-intracellular protein transport 4563 -0.13 9.3E-03PF3D7_0615200 conserved Plasmodium protein, unknown function 4564 -0.13 9.7E-03PF3D7_0609300 conserved Plasmodium protein, unknown function 4565 -0.13 9.0E-03PF3D7_0816400 conserved Plasmodium protein, unknown function 4566 -0.13 9.0E-03PF3D7_1106200 conserved Plasmodium protein, unknown function 4567 -0.13 9.1E-03PF3D7_0610800 transketolase 4568 -0.13 9.0E-03PF3D7_1304500 small heat shock protein, putative GO-0009408-response to heat 4569 -0.13 9.2E-03PF3D7_0819600 conserved Plasmodium protein, unknown function 4570 -0.13 8.9E-03PF3D7_0911900 falstatin 4571 -0.13 8.9E-03PF3D7_1445400 protein serine/threonine kinase-1 GO-0006468-protein phosphorylation 4572 -0.13 8.9E-03PF3D7_1008500 conserved Plasmodium membrane protein, unknown function 4573 -0.13 8.8E-03PF3D7_0402900 probable protein, unknown function 4574 -0.13 9.0E-03PF3D7_0827500 apicoplast ribosomal protein L21 precursor, putative GO-0006412-translation 4575 -0.13 8.7E-03PF3D7_0902500 serine/threonine protein kinase, FIKK family GO-0006468-protein phosphorylation 4576 -0.14 8.6E-03PF3D7_0702100 Plasmodium exported protein (PHISTb), unknown function, pseudogene 4577 -0.14 8.6E-03PF3D7_0806200 conserved Plasmodium membrane protein, unknown function 4578 -0.14 8.7E-03PF3D7_0722500 cell cycle control protein cwf15, putative GO-0008380-RNA splicing 4579 -0.14 8.6E-03PF3D7_0815300 FAD-dependent monooxygenase, putative 4580 -0.14 8.6E-03PF3D7_1438600 conserved protein, unknown function 4581 -0.14 8.5E-03PF3D7_0511200 stearoyl-CoA desaturase GO-0055114-oxidation-reduction process 4582 -0.14 8.4E-03PF3D7_1247100 conserved Plasmodium protein, unknown function 4583 -0.14 8.3E-03PF3D7_0211300 conserved Plasmodium protein, unknown function 4584 -0.14 8.3E-03PF3D7_0206500 conserved Plasmodium protein, unknown function 4585 -0.14 8.3E-03PF3D7_0204000 conserved Plasmodium protein, unknown function 4586 -0.14 8.1E-03PF3D7_0504400 ATP-dependent helicase, putative 4587 -0.14 8.0E-03PF3D7_1238000 COPI associated protein, putative 4588 -0.14 8.2E-03PF3D7_1362500 exonuclease, putative 4589 -0.14 8.0E-03PF3D7_0304300 conserved Plasmodium protein, unknown function 4590 -0.14 7.9E-03PF3D7_1425300 conserved Plasmodium protein, unknown function 4591 -0.14 7.7E-03PF3D7_1437600 conserved Plasmodium protein, unknown function 4592 -0.14 7.8E-03PF3D7_0603700 phenylalanine--tRNA ligase, putative GO-0006412-translation 4593 -0.14 7.6E-03PF3D7_0813000 conserved Plasmodium protein, unknown function 4595 -0.14 7.5E-03PF3D7_0210200 conserved Plasmodium protein, unknown function 4596 -0.14 7.3E-03PF3D7_0707600 conserved Plasmodium protein, unknown function 4597 -0.14 7.5E-03PF3D7_0406900 conserved Plasmodium protein, unknown function 4598 -0.14 7.3E-03PF3D7_0220400 DnaJ protein, putative, pseudogene GO-0006457-protein folding 4599 -0.14 7.3E-03PF3D7_0604500 conserved Plasmodium protein, unknown function 4600 -0.14 7.1E-03PF3D7_0701600 Pfmc-2TM Maurer's cleft two transmembrane protein GO-0042000-translocation of peptides or proteins into host 4601 -0.14 7.1E-03PF3D7_0725000 exonuclease I, putative GO-0006310-DNA recombination 4602 -0.14 7.1E-03PF3D7_1341500 conserved Plasmodium protein, unknown function 4603 -0.14 7.3E-03PF3D7_1116500 folate transporter 2 4604 -0.14 7.0E-03PF3D7_0728400 conserved Plasmodium protein, unknown function 4605 -0.14 7.0E-03PF3D7_1342600 myosin A 4606 -0.14 6.9E-03PF3D7_1421000 conserved Plasmodium protein, unknown function 4607 -0.14 7.1E-03PF3D7_0710500 conserved Plasmodium protein, unknown function 4608 -0.14 6.8E-03PF3D7_1223500 conserved Plasmodium protein, unknown function 4609 -0.14 6.7E-03PF3D7_1470800 conserved Plasmodium protein, unknown function 4610 -0.14 6.6E-03PF3D7_0929300 conserved Plasmodium protein, unknown function 4611 -0.14 6.6E-03PF3D7_0913100 conserved Plasmodium protein, unknown function 4612 -0.14 6.7E-03PF3D7_0217100 ATP synthase F1, alpha subunit GO-0015986-ATP synthesis coupled proton transport 4613 -0.14 6.5E-03PF3D7_0731100 EMP1-trafficking protein 4614 -0.14 6.5E-03PF3D7_1436500 GTP-binding protein, putative 4615 -0.14 6.8E-03PF3D7_1242500 conserved protein, unknown function 4616 -0.14 6.6E-03PF3D7_1112000 conserved Plasmodium protein, unknown function GO-0006810-transport 4617 -0.14 6.5E-03PF3D7_1478100 Plasmodium exported protein (hyp13), unknown function 4618 -0.14 6.4E-03PF3D7_1319100 conserved protein, unknown function 4619 -0.14 6.2E-03PF3D7_0516700 ubiquitin carboxyl-terminal hydrolase 2, putative GO-0006511-ubiquitin-dependent protein catabolic process 4620 -0.14 6.2E-03PF3D7_0403400 conserved Plasmodium protein, unknown function 4621 -0.14 6.2E-03PF3D7_0605900 long chain polyunsaturated fatty acid elongation enzyme, putative 4622 -0.14 8.6E-03

PF3D7_0919200 PPPDE peptidase, putative 4623 -0.14 6.2E-03PF3D7_0623100 coronin binding protein, putative 4624 -0.14 5.8E-03PF3D7_0611300 conserved Plasmodium protein, unknown function 4625 -0.14 5.8E-03PF3D7_0802500 inositol phosphatase, putative 4626 -0.14 5.7E-03PF3D7_1352900 conserved Plasmodium protein, unknown function 4627 -0.14 5.7E-03PF3D7_1251200 coronin 4628 -0.14 5.7E-03PF3D7_1452000 rhoptry neck protein 2 4629 -0.14 5.5E-03PF3D7_0217200 conserved Plasmodium protein, unknown function 4630 -0.14 5.6E-03PF3D7_1214100 phosphatidylinositol-glycan biosynthesis class O protein, putative GO-0008152-metabolic process 4631 -0.14 5.5E-03

PF3D7_0925500 thioredoxin-like protein 2 GO-0045454-cell redox homeostasis 4632 -0.14 5.6E-03PF3D7_0926800 conserved Plasmodium protein, unknown function GO-0007165-signal transduction 4633 -0.14 5.6E-03PF3D7_0321700 microtubule and actin binding protein, putative 4634 -0.14 5.5E-03PF3D7_1114500 conserved Plasmodium protein, unknown function 4635 -0.14 5.5E-03PF3D7_0715300 calcium/calmodulin-dependent protein kinase, putative GO-0006468-protein phosphorylation 4636 -0.14 5.4E-03PF3D7_1439600 conserved Plasmodium protein, unknown function 4637 -0.14 5.5E-03

Page 7 of 13


Correl. Coef.

corrected p-value

PF3D7_1308400 conserved Plasmodium protein, unknown function 4638 -0.14 5.4E-03PF3D7_1209800 ATP synthase mitochondrial F1 complex assembly factor 1, putative 4639 -0.14 5.4E-03PF3D7_1365300 conserved Plasmodium protein, unknown function 4640 -0.14 5.3E-03PF3D7_1328100 proteasome subunit beta type 7 precursor, putative GO-0006511-ubiquitin-dependent protein catabolic process 4641 -0.14 5.3E-03PF3D7_1411400 plastid replication-repair enzyme GO-0006260-DNA replication 4642 -0.14 5.1E-03PF3D7_1303800 conserved Plasmodium protein, unknown function GO-0006281-DNA repair 4643 -0.14 5.1E-03PF3D7_1236400 conserved Plasmodium protein, unknown function 4644 -0.14 5.1E-03PF3D7_1322500 palmitoyltransferase, putative 4645 -0.14 5.6E-03PF3D7_1312400 translation initiation factor IF-2, putative GO-0006412-translation 4646 -0.14 5.1E-03PF3D7_0505500 DNA mismatch repair protein MSH6, putative GO-0006281-DNA repair 4647 -0.14 5.0E-03PF3D7_1441900 transcription factor TFIIH complex subunit Tfb5, putative 4648 -0.14 5.1E-03PF3D7_0312900 hypothetical protein 4649 -0.14 4.9E-03PF3D7_0305900 conserved Plasmodium protein, unknown function 4650 -0.14 5.1E-03PF3D7_1024000 conserved Plasmodium protein, unknown function 4651 -0.14 4.9E-03PF3D7_1310200 conserved Plasmodium protein, unknown function 4653 -0.14 4.9E-03PF3D7_1338000 conserved Plasmodium membrane protein, unknown function 4654 -0.14 4.6E-03PF3D7_0114300 exported protein family 4, pseudogene | Plasmodium exported protein, unknown

function, pseudogene4655 -0.14 7.3E-03

PF3D7_1313300 peptidyl-prolyl cis-trans isomerase, putative GO-0006457-protein folding 4656 -0.14 5.2E-03PF3D7_0409100 U4/U6 small nuclear ribonucleoprotein PRP31, putative GO-0008380-RNA splicing 4657 -0.14 4.5E-03PF3D7_1210400 general transcription factor 3C polypeptide 5, putative GO-0006351-transcription DNA-dependent 4658 -0.15 4.4E-03PF3D7_0912700 conserved Plasmodium protein, unknown function 4659 -0.15 4.4E-03PF3D7_1310500 conserved protein, unknown function 4660 -0.15 6.2E-03PF3D7_0927600 conserved Plasmodium protein, unknown function 4661 -0.15 4.2E-03PF3D7_0606600 conserved Plasmodium protein, unknown function 4662 -0.15 4.2E-03PF3D7_0108600 conserved Plasmodium protein, unknown function GO-0006457-protein folding 4663 -0.15 4.3E-03PF3D7_1404700 conserved Plasmodium protein, unknown function 4664 -0.15 4.4E-03PF3D7_1240100 early transcribed membrane protein 12 4665 -0.15 4.1E-03PF3D7_0611900 lsm12, putative 4666 -0.15 5.4E-03PF3D7_0104400 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 4667 -0.15 4.0E-03PF3D7_0313700 conserved Plasmodium protein, unknown function 4668 -0.15 4.0E-03PF3D7_0205700 conserved Plasmodium protein, unknown function 4669 -0.15 4.0E-03PF3D7_0935600 gametocytogenesis-implicated protein 4670 -0.15 3.9E-03PF3D7_0207400 serine repeat antigen 7 GO-0006508-proteolysis 4671 -0.15 3.9E-03PF3D7_1309700 conserved Plasmodium protein, unknown function GO-0015031-protein transport 4672 -0.15 3.9E-03PF3D7_0612000 conserved Plasmodium protein, unknown function GO-0006810-transport 4673 -0.15 3.9E-03PF3D7_1400200 rifin | PIR protein GO-0020033-antigenic variation 4674 -0.15 3.7E-03PF3D7_0918700 conserved Plasmodium protein, unknown function 4675 -0.15 3.7E-03PF3D7_0507400 conserved Plasmodium protein, unknown function 4676 -0.15 3.6E-03PF3D7_1147300 conserved Plasmodium protein, unknown function 4677 -0.15 3.6E-03PF3D7_0826400 dehydrodolichyl diphosphate synthetase, putative 4678 -0.15 3.8E-03PF3D7_1234200 conserved Plasmodium protein, unknown function, pseudogene 4679 -0.15 3.4E-03PF3D7_1236700 s-adenosyl-methyltransferase, putative 4680 -0.15 3.5E-03PF3D7_0625300 DNA polymerase 1, putative GO-0006260-DNA replication 4681 -0.15 3.4E-03PF3D7_1228000 conserved Plasmodium protein, unknown function 4682 -0.15 3.5E-03PF3D7_1229600 conserved Plasmodium protein, unknown function 4683 -0.15 3.3E-03PF3D7_0513300 purine nucleoside phosphorylase 4684 -0.15 3.4E-03PF3D7_0918300 eukaryotic translation initiation factor 3 subunit 5, putative GO-0006412-translation 4685 -0.15 3.2E-03PF3D7_1006200 DNA/RNA-binding protein Alba 3 4686 -0.15 3.3E-03PF3D7_0805700 serine/threonine protein kinase, FIKK family GO-0006468-protein phosphorylation 4687 -0.15 3.2E-03PF3D7_1013600 conserved Plasmodium protein, unknown function 4688 -0.15 3.1E-03PF3D7_0916400 conserved Plasmodium protein, unknown function 4689 -0.15 3.1E-03PF3D7_1029300 conserved Plasmodium protein, unknown function 4690 -0.15 3.1E-03PF3D7_1325900 conserved Plasmodium protein, unknown function 4691 -0.15 3.1E-03PF3D7_1200600 erythrocyte membrane protein 1, PfEMP1 GO-0020033-antigenic variation 4692 -0.15 3.1E-03PF3D7_0602500 geranylgeranyltransferase, putative 4693 -0.15 3.1E-03PF3D7_0210300 monocarboxylate transporter, putative 4694 -0.15 3.2E-03PF3D7_0714000 histone H2B variant GO-0006334-nucleosome assembly 4695 -0.15 3.5E-03PF3D7_1029600 adenosine deaminase 4696 -0.15 3.0E-03PF3D7_1411600 GTP-binding protein, putative 4697 -0.15 3.0E-03PF3D7_0936800 Plasmodium exported protein (PHISTc), unknown function 4698 -0.15 3.0E-03PF3D7_0222100 Pfmc-2TM Maurer's cleft two transmembrane protein GO-0042000-translocation of peptides or proteins into host 4699 -0.15 3.0E-03PF3D7_1110700 actin-like protein, putative GO-0007010-cytoskeleton organization 4700 -0.15 3.0E-03PF3D7_0419700 apical merozoite protein GO-0016255-attachment of GPI anchor to protein 4701 -0.15 3.1E-03PF3D7_1359800 ADP-ribosylation factor, putative GO-0007264-small GTPase mediated signal transduction 4702 -0.15 3.2E-03PF3D7_0211200 ras-related protein Rab-5A GO-0015031-protein transport 4703 -0.15 2.9E-03PF3D7_0301900 conserved Plasmodium protein, unknown function 4704 -0.15 2.9E-03PF3D7_0213900 conserved Plasmodium protein, unknown function 4705 -0.15 2.9E-03PF3D7_1205000 conserved Plasmodium protein, unknown function 4706 -0.15 2.8E-03PF3D7_0609000 conserved Plasmodium protein, unknown function 4707 -0.15 2.8E-03PF3D7_1027000 conserved Plasmodium protein, unknown function 4708 -0.15 2.8E-03PF3D7_1106400 conserved Plasmodium protein, unknown function 4709 -0.15 2.9E-03PF3D7_0629000 conserved protein, unknown function GO-0008152-metabolic process 4710 -0.15 2.7E-03PF3D7_1224500 histone chaperone ASF1, putative 4711 -0.15 2.7E-03PF3D7_1036600 conserved Plasmodium protein, unknown function 4712 -0.15 2.7E-03PF3D7_0928800 serine/threonine protein kinase, putative GO-0006468-protein phosphorylation 4713 -0.15 2.7E-03PF3D7_1002100 EMP1-trafficking protein 4714 -0.15 2.5E-03PF3D7_0413500 phosphoglucomutase-2 GO-0006096-glycolysis 4715 -0.15 2.7E-03PF3D7_1209400 conserved Plasmodium protein, unknown function 4716 -0.15 2.5E-03PF3D7_1330700 GPI transamidase subunit PIG-U, putative GO-0006506-GPI anchor biosynthetic process 4717 -0.15 2.5E-03PF3D7_0617500 rifin, pseudogene | PIR protein, pseudogene 4718 -0.15 2.5E-03PF3D7_1356400 phosphatase 2A regulatory subunit-related protein, putative GO-0007165-signal transduction 4719 -0.15 2.5E-03PF3D7_0726500 ubiquitin carboxyl-terminal hydrolase, putative GO-0006511-ubiquitin-dependent protein catabolic process 4720 -0.15 2.4E-03PF3D7_1364200 conserved Plasmodium protein, unknown function 4721 -0.15 2.4E-03

Page 8 of 13


Correl. Coef.

corrected p-value

PF3D7_0511500 RNA pseudouridylate synthase, putative GO-0001522-pseudouridine synthesis 4722 -0.15 2.4E-03PF3D7_1002400 RNA-binding protein, putative 4723 -0.15 2.4E-03PF3D7_1453400 conserved Plasmodium protein, unknown function 4724 -0.15 2.4E-03PF3D7_0402200 surface-associated interspersed protein 4.1 (SURFIN 4.1), pseudogene 4725 -0.15 2.4E-03PF3D7_0616200 Ndc80 homologue, putative 4726 -0.15 2.3E-03PF3D7_1147400 conserved Plasmodium protein, unknown function 4727 -0.15 2.5E-03PF3D7_0922200 S-adenosylmethionine synthetase 4728 -0.15 2.3E-03PF3D7_0318600 cleavage and polyadenylation specificity factor, putative 4729 -0.16 2.2E-03PF3D7_1319200 conserved Plasmodium protein, unknown function GO-0008033-tRNA processing 4730 -0.16 2.4E-03PF3D7_1126500 conserved Plasmodium protein, unknown function 4731 -0.16 2.2E-03PF3D7_1302000 EMP1-trafficking protein 4732 -0.16 2.2E-03PF3D7_1143300 DNA-directed RNA polymerase I, putative GO-0006351-transcription DNA-dependent 4733 -0.16 2.1E-03PF3D7_0216400 vacuolar protein sorting-associated protein 45, putative GO-0006886-intracellular protein transport 4734 -0.16 2.2E-03PF3D7_1027700 centrin-3 4735 -0.16 2.1E-03PF3D7_1019900 autophagy-related protein 8 4736 -0.16 2.1E-03PF3D7_1121000 palmitoyltransferase, putative 4737 -0.16 2.9E-03PF3D7_1016000 conserved Plasmodium protein, unknown function 4738 -0.16 2.0E-03PF3D7_0531400 conserved Plasmodium protein, unknown function 4739 -0.16 2.0E-03PF3D7_0106000 conserved Plasmodium protein, unknown function 4740 -0.16 2.0E-03PF3D7_1337800 calcium-dependent protein kinase 5 GO-0006468-protein phosphorylation 4741 -0.16 2.0E-03PF3D7_0934400 transcription factor with AP2 domain(s), putative GO-0006355-regulation of transcription DNA-dependent 4742 -0.16 2.0E-03PF3D7_0514100 ATP-dependent DNA helicase UvrD GO-0006281-DNA repair 4743 -0.16 1.8E-03PF3D7_1366300 conserved Plasmodium protein, unknown function 4744 -0.16 1.8E-03PF3D7_1008600 zinc finger C-x8-C-x5-C-x3-H type, putative 4745 -0.16 3.2E-03PF3D7_1213300 conserved Plasmodium protein, unknown function 4746 -0.16 2.0E-03PF3D7_0419600 ran binding protein 1, putative GO-0006260-DNA replication 4747 -0.16 1.9E-03PF3D7_1246100 delta-aminolevulinic acid synthetase 4748 -0.16 2.0E-03PF3D7_0300900 stevor-like | PIR protein 4749 -0.16 2.1E-03PF3D7_0833000 rifin | PIR protein 4750 -0.16 4.7E-03PF3D7_0709700 lysophospholipase, putative 4751 -0.16 1.7E-03PF3D7_1308100 CCAAT-binding transcription factor, putative GO-0006355-regulation of transcription DNA-dependent 4752 -0.16 1.8E-03PF3D7_1020700 ribosomal processing ATPase, putative GO-0042254-ribosome biogenesis 4753 -0.16 1.6E-03PF3D7_0522600 inner membrane complex protein 4754 -0.16 1.6E-03PF3D7_1218400 triose or hexose phosphate/phosphate translocator, putative 4755 -0.16 1.6E-03PF3D7_1220900 heterochromatin protein 1 4756 -0.16 1.6E-03PF3D7_1208200 cysteine repeat modular protein 3 4757 -0.16 1.6E-03PF3D7_0914700 transporter, putative 4758 -0.16 1.6E-03PF3D7_1015400 conserved Plasmodium protein, unknown function 4759 -0.16 1.5E-03PF3D7_0809800 conserved Plasmodium protein, unknown function 4760 -0.16 1.5E-03PF3D7_1452700 U1 snRNA associated protein, putative 4761 -0.16 1.5E-03PF3D7_0309800 YTH domain-containing protein, putative 4762 -0.16 1.5E-03PF3D7_0306000 conserved Plasmodium protein, unknown function 4763 -0.16 1.5E-03PF3D7_0103900 parasite-infected erythrocyte surface protein 4764 -0.16 1.5E-03PF3D7_1124800 nuclear preribosomal assembly protein, putative GO-0042254-ribosome biogenesis 4765 -0.16 1.5E-03PF3D7_0714300 palmitoyltransferase, putative 4766 -0.16 1.4E-03PF3D7_0702300 sporozoite threonine and asparagine-rich protein 4767 -0.16 1.4E-03PF3D7_1416100 root hair defective 3 GTP-binding protein (RHD3) homolog 4768 -0.16 1.4E-03PF3D7_1406700 phosphatase, putative 4769 -0.16 1.4E-03PF3D7_1209700 conserved Plasmodium protein, unknown function 4770 -0.16 1.4E-03PF3D7_1320800 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate

dehydrogenase complex, putativeGO-0006099-tricarboxylic acid cycle 4771 -0.16 1.3E-03

PF3D7_1336600 conserved Plasmodium protein, unknown function 4772 -0.16 1.3E-03PF3D7_1009400 zinc finger protein, putative 4773 -0.16 1.2E-03PF3D7_1221300 conserved Plasmodium protein, unknown function 4774 -0.16 1.2E-03PF3D7_0721200 conserved Plasmodium protein, unknown function 4775 -0.16 1.2E-03PF3D7_1107100 nucleic acid binding protein, putative GO-0006139-nucleobase-containing compound metabolic process 4776 -0.16 1.1E-03

PF3D7_1025100 glutamine--fructose-6-phosphate aminotransferase [isomerizing] GO-0005975-carbohydrate metabolic process 4777 -0.16 1.1E-03PF3D7_0301000 acyl-CoA synthetase GO-0006631-fatty acid metabolic process 4778 -0.16 1.3E-03PF3D7_0916500 apicoplast Ufd1 precursor | ubiquitin fusion degradation protein 1 | ubiquitin fusion

degradation protein 1GO-0010564-regulation of cell cycle process 4779 -0.16 1.1E-03

PF3D7_0605800 DNA repair protein RAD50, putative 4780 -0.16 1.0E-03PF3D7_1244000 glucose inhibited division protein a homologue, putative GO-0008033-tRNA processing 4781 -0.17 1.0E-03PF3D7_1102800 early transcribed membrane protein 11.2 4782 -0.17 1.0E-03PF3D7_0924000 patatin-like phospholipase, putative GO-0006629-lipid metabolic process 4783 -0.17 1.0E-03PF3D7_1107300 polyadenylate-binding protein-interacting protein 1, putative GO-0016070-RNA metabolic process 4784 -0.17 1.0E-03PF3D7_0933800 delta tubulin, putative GO-0007018-microtubule-based movement 4785 -0.17 9.9E-04PF3D7_1333500 conserved Plasmodium protein, unknown function 4786 -0.17 9.0E-04PF3D7_1412000 p1/s1 nuclease, putative 4787 -0.17 9.3E-04PF3D7_0905500 conserved Plasmodium protein, unknown function GO-0006810-transport 4788 -0.17 8.7E-04PF3D7_1405200 sybindin-like protein, putative GO-0006888-ER to Golgi vesicle-mediated transport 4789 -0.17 8.7E-04PF3D7_1303500 sodium/hydrogen exchanger, Na+, H+ antiporter 4790 -0.17 8.6E-04PF3D7_1465000 conserved Plasmodium protein, unknown function 4791 -0.17 1.0E-03PF3D7_0219700 Plasmodium exported protein (PHISTc), unknown function 4792 -0.17 8.5E-04PF3D7_1411800 conserved Plasmodium protein, unknown function 4793 -0.17 7.9E-04PF3D7_0814300 ATPase, putative GO-0010564-regulation of cell cycle process 4794 -0.17 7.8E-04PF3D7_1315300 conserved Plasmodium protein, unknown function 4795 -0.17 7.8E-04PF3D7_1422300 DnaJ protein, putative 4796 -0.17 7.9E-04PF3D7_1363000 conserved Plasmodium protein, unknown function 4797 -0.17 7.5E-04PF3D7_1305000 conserved Plasmodium protein, unknown function GO-0015031-protein transport 4798 -0.17 7.2E-04PF3D7_1009300 conserved Plasmodium protein, unknown function 4799 -0.17 7.3E-04PF3D7_0913900 arginine--tRNA ligase, putative GO-0006412-translation 4800 -0.17 7.1E-04PF3D7_0501400 interspersed repeat antigen 4801 -0.17 7.0E-04PF3D7_1225300 conserved Plasmodium protein, unknown function 4802 -0.17 7.1E-04

Page 9 of 13


Correl. Coef.

corrected p-value

PF3D7_1024700 conserved Plasmodium protein, unknown function 4803 -0.17 7.0E-04PF3D7_0513200 conserved Plasmodium protein, unknown function GO-0006397-mRNA processing 4804 -0.17 7.0E-04PF3D7_0804500 conserved Plasmodium membrane protein, unknown function 4805 -0.17 6.9E-04PF3D7_1121200 conserved Plasmodium protein, unknown function 4806 -0.17 6.9E-04PF3D7_1329600 conserved Plasmodium protein, unknown function 4807 -0.17 6.8E-04PF3D7_1012300 ubiquinol-cytochrome c reductase complex subunit, putative 4808 -0.17 6.8E-04PF3D7_1428600 peptide chain release factor 1, putative 4809 -0.17 6.3E-04PF3D7_1410700 conserved Plasmodium protein, unknown function 4810 -0.17 6.4E-04PF3D7_0825600 cytochrome c oxidase assembly protein, putative 4811 -0.17 6.0E-04PF3D7_0102200 ring-infected erythrocyte surface antigen 4812 -0.17 5.9E-04PF3D7_0930200 leucine-rich repeat protein 4813 -0.17 5.9E-04PF3D7_0803600 conserved Plasmodium protein, unknown function 4814 -0.17 5.7E-04PF3D7_1136000 conserved Plasmodium protein, unknown function 4815 -0.17 5.5E-04PF3D7_1036800 acetyl-CoA transporter, putative 4816 -0.17 5.4E-04PF3D7_0303400 palmitoyltransferase 4817 -0.17 5.4E-04PF3D7_0720800 Ham1-like protein, putative 4818 -0.17 5.2E-04PF3D7_1444500 eukaryotic initiation factor 2alpha kinase 1 GO-0006468-protein phosphorylation 4819 -0.17 5.1E-04PF3D7_0801600 conserved Plasmodium protein, unknown function 4820 -0.17 5.0E-04PF3D7_1200500 rifin | PIR protein GO-0020033-antigenic variation 4821 -0.17 9.6E-04PF3D7_0504000 cation transporting P-ATPase GO-0006754-ATP biosynthetic process 4822 -0.17 4.9E-04PF3D7_0929200 RNA-binding protein, putative 4823 -0.17 4.9E-04PF3D7_0509200 leucine-rich repeat protein 4824 -0.17 1.1E-03PF3D7_0304500 1-cys-glutaredoxin-like protein-1 GO-0045454-cell redox homeostasis 4825 -0.17 5.5E-04PF3D7_1405000 conserved Plasmodium protein, unknown function 4826 -0.17 4.8E-04PF3D7_1138200 conserved Plasmodium membrane protein, unknown function GO-0006810-transport 4827 -0.17 4.8E-04PF3D7_0501600 rhoptry-associated protein 2 GO-0030260-entry into host cell 4828 -0.17 4.8E-04PF3D7_1002500 conserved Plasmodium protein, unknown function GO-0055114-oxidation-reduction process 4829 -0.17 4.7E-04PF3D7_1033100 S-adenosylmethionine decarboxylase/ornithine decarboxylase 4830 -0.18 4.5E-04PF3D7_1462400 conserved Plasmodium protein, unknown function 4831 -0.18 4.5E-04PF3D7_1013700 conserved Plasmodium protein, unknown function 4832 -0.18 4.3E-04PF3D7_1324500 DEAD box helicase, putative GO-0006139-nucleobase-containing compound metabolic process 4833 -0.18 4.0E-04

PF3D7_1208100 conserved Plasmodium protein, unknown function 4834 -0.18 3.9E-04PF3D7_0805200 conserved Plasmodium protein, unknown function 4835 -0.18 4.8E-04PF3D7_1349100 nucleoside diphosphate hydrolase, putative GO-0006139-nucleobase-containing compound metabolic process 4836 -0.18 3.8E-04

PF3D7_1434400 conserved Plasmodium membrane protein, unknown function GO-0016255-attachment of GPI anchor to protein 4837 -0.18 3.8E-04PF3D7_1122500 conserved Plasmodium protein, unknown function 4838 -0.18 3.8E-04PF3D7_0926000 protein kinase, putative GO-0006468-protein phosphorylation 4839 -0.18 3.7E-04PF3D7_1245000 conserved Plasmodium protein, unknown function 4840 -0.18 3.5E-04PF3D7_1406300 glycerophosphodiester phosphodiesterase GO-0006629-lipid metabolic process 4841 -0.18 3.5E-04PF3D7_1212900 bromodomain protein, putative 4842 -0.18 3.5E-04PF3D7_1402200 conserved Plasmodium protein, unknown function GO-0006412-translation 4843 -0.18 7.3E-04PF3D7_0802600 adenylyl cyclase beta GO-0006468-protein phosphorylation 4844 -0.18 3.3E-04PF3D7_0915000 type II NADH 4845 -0.18 3.3E-04PF3D7_1409700 conserved Plasmodium protein, unknown function 4846 -0.18 3.3E-04PF3D7_1304900 DNA-directed RNA polymerase 2, putative GO-0006366-transcription from RNA polymerase II promoter 4847 -0.18 3.5E-04PF3D7_0511600 apical rhoptry neck protein 4848 -0.18 3.5E-04PF3D7_0933500 gamma-tubulin complex component, putative 4849 -0.18 3.3E-04PF3D7_0921600 tetratricopeptide repeat family protein, putative 4850 -0.18 3.2E-04PF3D7_0728500 conserved Plasmodium protein, unknown function 4851 -0.18 3.3E-04PF3D7_0406800 conserved Plasmodium protein, unknown function GO-0006412-translation 4852 -0.18 3.0E-04PF3D7_1314300 conserved Plasmodium protein, unknown function 4853 -0.18 3.0E-04PF3D7_0713400 serpentine receptor, putative 4854 -0.18 3.0E-04PF3D7_1420200 tetratricopeptide repeat family protein, putative 4855 -0.18 3.0E-04PF3D7_0322000 peptidyl-prolyl cis-trans isomerase CYPA GO-0006457-protein folding 4856 -0.18 3.0E-04PF3D7_1430200 plasmepsin IX GO-0006508-proteolysis 4857 -0.18 3.0E-04PF3D7_0609700 conserved Plasmodium protein, unknown function 4858 -0.18 2.9E-04PF3D7_1014500 conserved Plasmodium protein, unknown function 4859 -0.18 2.9E-04PF3D7_0726700 conserved Plasmodium protein, unknown function 4860 -0.18 2.9E-04PF3D7_0218100 conserved Plasmodium membrane protein, unknown function GO-0006810-transport 4861 -0.18 2.9E-04PF3D7_0935000 small nuclear ribonucleoprotein (snRNP), putative 4862 -0.18 2.9E-04PF3D7_1001200 acyl-CoA binding protein, isoform 2, ACBP2 GO-0006631-fatty acid metabolic process 4863 -0.18 2.8E-04PF3D7_0820900 conserved Plasmodium protein, unknown function 4864 -0.18 2.7E-04PF3D7_0705500 inositol-phosphate phosphatase, putative 4865 -0.18 2.7E-04PF3D7_0301600 Plasmodium exported protein (hyp1), unknown function 4866 -0.18 2.7E-04PF3D7_0305300 conserved Plasmodium membrane protein, unknown function 4867 -0.18 2.7E-04PF3D7_1203400 transporter, putative 4868 -0.18 2.7E-04PF3D7_1462300 conserved Plasmodium protein, unknown function 4869 -0.18 2.7E-04PF3D7_0422500 pre-mRNA-splicing helicase BRR2, putative GO-0000375-RNA splicing via transesterification reactions 4870 -0.18 2.6E-04PF3D7_1232600 conserved Plasmodium protein, unknown function 4871 -0.18 2.4E-04PF3D7_0102700 merozoite-associated tryptophan-rich antigen, putative 4872 -0.18 2.3E-04PF3D7_1122100 conserved Plasmodium protein, unknown function GO-0016255-attachment of GPI anchor to protein 4873 -0.18 2.3E-04PF3D7_1421100 conserved Plasmodium protein, unknown function 4874 -0.18 2.2E-04PF3D7_1407800 plasmepsin IV 4875 -0.18 2.2E-04PF3D7_0626900 mitochondrial ribosomal protein L46 precursor, putative 4876 -0.18 2.0E-04PF3D7_1023800 conserved Plasmodium protein, unknown function 4877 -0.18 2.1E-04PF3D7_0823000 protein kinase, putative GO-0006468-protein phosphorylation 4878 -0.19 2.0E-04PF3D7_0415600 GTP:AMP phosphotransferase GO-0006139-nucleobase-containing compound metabolic process 4879 -0.19 2.3E-04

PF3D7_1335800 conserved Plasmodium protein, unknown function 4880 -0.19 2.0E-04PF3D7_1454400 aminopeptidase P GO-0006508-proteolysis 4881 -0.19 2.0E-04PF3D7_1119400 ubiquitin-protein ligase, putative GO-0006464-cellular protein modification process 4882 -0.19 1.9E-04PF3D7_0104800 novel putative transporter 1 4883 -0.19 1.9E-04

Page 10 of 13


Correl. Coef.

corrected p-value

PF3D7_1010100 conserved Plasmodium protein, unknown function 4884 -0.19 2.3E-04PF3D7_1315100 serine/threonine protein kinase GO-0006468-protein phosphorylation 4885 -0.19 1.8E-04PF3D7_0622900 transcription factor with AP2 domain(s), putative GO-0006355-regulation of transcription DNA-dependent 4886 -0.19 1.8E-04PF3D7_0618600 rhomboid protease ROM10 GO-0006465-signal peptide processing 4887 -0.19 2.9E-04PF3D7_1412200 conserved Plasmodium protein, unknown function 4888 -0.19 1.7E-04PF3D7_1228800 conserved Plasmodium protein, unknown function 4889 -0.19 1.6E-04PF3D7_0727100 conserved Plasmodium protein, unknown function GO-0006817-phosphate ion transport 4890 -0.19 1.6E-04PF3D7_1032600 conserved protein, unknown function 4891 -0.19 1.9E-04PF3D7_1357600 conserved Plasmodium protein, unknown function 4892 -0.19 1.5E-04PF3D7_1138700 conserved Plasmodium protein, unknown function 4893 -0.19 1.3E-04PF3D7_0707500 conserved Plasmodium protein, unknown function 4894 -0.19 1.3E-04PF3D7_0629100 nicotinate phosphoribosyltransferase, putative 4895 -0.19 1.3E-04PF3D7_1112600 DNA helicase, putative GO-0006281-DNA repair 4896 -0.19 1.2E-04PF3D7_1134400 conserved Plasmodium protein, unknown function 4897 -0.19 1.2E-04PF3D7_1030300 conserved Plasmodium protein, unknown function GO-0006412-translation 4898 -0.19 1.1E-04PF3D7_1419200 conserved Plasmodium protein, unknown function GO-0045454-cell redox homeostasis 4899 -0.19 1.1E-04PF3D7_1450300 DNA polymerase delta interacting protein, putative 4900 -0.19 1.1E-04PF3D7_1430600 exodeoxyribonuclease III, putative GO-0006281-DNA repair 4901 -0.19 1.1E-04PF3D7_1034900 methionine--tRNA ligase, putative GO-0006412-translation 4902 -0.19 1.1E-04PF3D7_0215800 origin recognition complex subunit 5 4903 -0.19 1.1E-04PF3D7_1004200 conserved Plasmodium membrane protein, unknown function GO-0006810-transport 4904 -0.19 1.0E-04PF3D7_1224400 conserved Plasmodium protein, unknown function 4905 -0.19 9.8E-05PF3D7_1400600 rifin | PIR protein GO-0020033-antigenic variation 4906 -0.19 9.8E-05PF3D7_1430400 conserved Plasmodium protein, unknown function GO-0009405-pathogenesis 4907 -0.19 9.6E-05PF3D7_1252900 Plasmodium exported protein, unknown function GO-0043687-post-translational protein modification 4908 -0.19 9.5E-05PF3D7_0922700 pre-mRNA splicing factor, putative GO-0008380-RNA splicing 4909 -0.19 9.5E-05PF3D7_1357200 glutamate--tRNA ligase GO-0006412-translation 4910 -0.19 8.6E-05PF3D7_1021000 conserved Plasmodium protein, unknown function GO-0006412-translation 4911 -0.19 8.6E-05PF3D7_1108200 D-tyrosyl-tRNA(Tyr) deacylase 4912 -0.19 8.6E-05PF3D7_0414900 armadillo-domain containing rhoptry protein 4913 -0.19 1.7E-04PF3D7_1205500 zinc finger protein, putative 4914 -0.19 8.3E-05PF3D7_1302500 conserved Plasmodium protein, unknown function GO-0006351-transcription DNA-dependent 4915 -0.19 8.3E-05PF3D7_0620400 merozoite surface protein 10 GO-0016255-attachment of GPI anchor to protein 4916 -0.20 7.8E-05PF3D7_0514800 kinase, putative 4917 -0.20 7.4E-05PF3D7_1226400 conserved Plasmodium protein, unknown function 4918 -0.20 7.3E-05PF3D7_1462200 conserved Plasmodium protein, unknown function 4919 -0.20 7.4E-05PF3D7_1038000 antigen UB05 4920 -0.20 7.4E-05PF3D7_0316900 E3 ubiquitin-protein ligase, putative 4921 -0.20 6.4E-05PF3D7_1314700 conserved Plasmodium protein, unknown function 4922 -0.20 5.9E-05PF3D7_0623400 RNA-binding protein mei2 homologue, putative 4923 -0.20 5.9E-05PF3D7_0927700 serine/threonine protein phosphatase, putative 4924 -0.20 5.9E-05PF3D7_1420500 conserved Plasmodium membrane protein, unknown function 4925 -0.20 6.0E-05PF3D7_0919000 nucleosome assembly protein GO-0006334-nucleosome assembly 4926 -0.20 1.1E-04PF3D7_0623000 chorismate synthase 4927 -0.20 5.3E-05PF3D7_1451500 pre-mRNA-splicing factor CWF18, putative 4928 -0.20 8.0E-05PF3D7_1320700 conserved Plasmodium protein, unknown function 4929 -0.20 5.2E-05PF3D7_0106500 conserved Plasmodium protein, unknown function 4930 -0.20 5.1E-05PF3D7_1234300 DNA polymerase epsilon subunit b, putative GO-0006260-DNA replication 4931 -0.20 5.1E-05PF3D7_1137200 conserved Plasmodium protein, unknown function 4932 -0.20 5.2E-05PF3D7_0926400 monocarboxylate transporter, putative 4933 -0.20 4.8E-05PF3D7_1365700 conserved Plasmodium membrane protein, unknown function 4934 -0.20 4.4E-05PF3D7_1224700 conserved Plasmodium protein, unknown function GO-0006351-transcription DNA-dependent 4935 -0.20 4.1E-05PF3D7_1328400 conserved Plasmodium protein, unknown function 4936 -0.20 4.0E-05PF3D7_1136200 conserved Plasmodium protein, unknown function GO-0016255-attachment of GPI anchor to protein 4937 -0.20 3.9E-05PF3D7_0209500 conserved Plasmodium protein, unknown function GO-0006412-translation 4938 -0.20 5.2E-05PF3D7_1456600 mitochondrial ribosomal protein L28 precursor, putative 4939 -0.20 4.0E-05PF3D7_0703700 conserved Plasmodium protein, unknown function 4940 -0.20 3.3E-05PF3D7_0530000 conserved Plasmodium protein, unknown function 4941 -0.20 3.3E-05PF3D7_0109900 phosphatidate cytidylyltransferase, putative 4942 -0.20 3.1E-05PF3D7_0419200 CGI-141 protein homolog, putative GO-0016192-vesicle-mediated transport 4943 -0.20 3.2E-05PF3D7_1119700 conserved Plasmodium protein, unknown function GO-0006355-regulation of transcription DNA-dependent 4944 -0.20 3.0E-05PF3D7_1130000 phosphoacetylglucosamine mutase, putative GO-0005975-carbohydrate metabolic process 4945 -0.21 3.0E-05PF3D7_1221100 conserved Plasmodium protein, unknown function 4946 -0.21 3.0E-05PF3D7_0922800 conserved Plasmodium protein, unknown function GO-0006412-translation 4947 -0.21 2.9E-05PF3D7_1334600 MSP7-like protein 4948 -0.21 2.9E-05PF3D7_0318300 conserved Plasmodium protein, unknown function 4949 -0.21 2.8E-05PF3D7_1334800 MSP7-like protein 4950 -0.21 2.9E-05PF3D7_0935800 cytoadherence linked asexual protein 9 GO-0016337-cell-cell adhesion 4951 -0.21 2.5E-05PF3D7_0816200 vacuolar protein-sorting protein VPS2, putative GO-0015031-protein transport 4952 -0.21 5.0E-05PF3D7_0407900 AAA family ATPase, putative 4953 -0.21 2.5E-05PF3D7_0521800 nucleotide binding protein, putative 4954 -0.21 2.5E-05PF3D7_1322200 conserved Plasmodium protein, unknown function GO-0007049-cell cycle 4955 -0.21 2.3E-05PF3D7_1248500 bax inhibitor 1, putative 4956 -0.21 2.3E-05PF3D7_1343400 DNA repair protein RAD5, putative 4957 -0.21 2.1E-05PF3D7_1357300 dynein light chain, putative 4958 -0.21 7.2E-05PF3D7_1237700 conserved Plasmodium membrane protein, unknown function 4959 -0.21 2.1E-05PF3D7_1010300 succinate dehydrogenase subunit 4, putative GO-0006810-transport 4960 -0.21 2.5E-05PF3D7_0424800 Plasmodium exported protein (PHISTb), unknown function 4961 -0.21 1.9E-05PF3D7_0830600 Plasmodium exported protein (PHISTc), unknown function 4962 -0.21 1.9E-05PF3D7_1120500 tRNA nucleotidyltransferase, putative GO-0006396-RNA processing 4963 -0.21 1.9E-05PF3D7_1227700 conserved Plasmodium protein, unknown function 4964 -0.21 1.9E-05PF3D7_0721500 conserved Plasmodium membrane protein, unknown function 4965 -0.21 1.8E-05PF3D7_0501500 rhoptry-associated protein 3 4966 -0.21 1.7E-05

Page 11 of 13


Correl. Coef.

corrected p-value

PF3D7_1245300 ubiquitin conjugating enzyme E2, putative GO-0043687-post-translational protein modification 4967 -0.21 1.7E-05PF3D7_1339400 conserved Plasmodium protein, unknown function 4968 -0.21 1.8E-05PF3D7_0918200 50S ribosomal protein L3, apicoplast, putative GO-0006412-translation 4969 -0.21 1.8E-05PF3D7_1358200 conserved Plasmodium protein, unknown function GO-0007155-cell adhesion 4970 -0.21 1.5E-05PF3D7_1028200 zinc finger, C3HC4 type, putative 4971 -0.21 1.3E-05PF3D7_1439500 CCAAT-binding transcription factor, putative 4972 -0.21 1.2E-05PF3D7_1253700 rifin | PIR protein GO-0020033-antigenic variation 4973 -0.21 4.8E-05PF3D7_0818600 conserved Plasmodium protein, unknown function 4974 -0.21 1.4E-05PF3D7_0819000 conserved Plasmodium protein, unknown function GO-0006397-mRNA processing 4975 -0.22 1.0E-05PF3D7_0813800 GDP-mannose 4,6-dehydratase 4976 -0.22 1.0E-05PF3D7_1225100 isoleucine--tRNA ligase, putative GO-0006412-translation 4977 -0.22 9.9E-06PF3D7_1425800 conserved Plasmodium protein, unknown function 4978 -0.22 9.5E-06PF3D7_0811300 CCR4-associated factor 1 4979 -0.22 8.9E-06PF3D7_0908100 conserved Plasmodium membrane protein, unknown function 4980 -0.22 1.0E-05PF3D7_0818200 14-3-3 protein 14-3-3 4981 -0.22 1.1E-05PF3D7_1139800 conserved Plasmodium protein, unknown function 4982 -0.22 8.3E-06PF3D7_1018300 conserved Plasmodium protein, unknown function GO-0006508-proteolysis 4983 -0.22 7.9E-06PF3D7_1478800 Plasmodium exported protein, unknown function 4984 -0.22 7.2E-06PF3D7_0308800 conserved protein, unknown function 4985 -0.22 6.7E-06PF3D7_0406700 conserved Plasmodium protein, unknown function 4986 -0.22 6.4E-06PF3D7_0525200 conserved Plasmodium protein, unknown function GO-0051276-chromosome organization 4987 -0.22 6.2E-06PF3D7_1251700 tryptophan--tRNA ligase, putative GO-0006412-translation 4988 -0.22 5.9E-06PF3D7_0710200 conserved Plasmodium protein, unknown function 4989 -0.22 5.8E-06PF3D7_1213200 conserved Plasmodium protein, unknown function 4990 -0.22 5.7E-06PF3D7_0302700 CDGSH iron-sulfur domain-containing protein, putative 4991 -0.22 5.5E-06PF3D7_1360700 E3 SUMO-protein ligase PIAS, putative 4992 -0.22 5.2E-06PF3D7_0310200 phd finger protein, putative 4993 -0.22 5.1E-06PF3D7_0619800 conserved Plasmodium membrane protein, unknown function 4994 -0.22 5.0E-06PF3D7_1427300 conserved Plasmodium protein, unknown function 4995 -0.22 4.9E-06PF3D7_1331600 protein tyrosine phosphatase, putative 4996 -0.22 4.8E-06PF3D7_1012700 protein phosphatase, putative 4997 -0.22 4.5E-06PF3D7_0320900 histone H2A variant, putative GO-0006334-nucleosome assembly 4998 -0.22 5.1E-06PF3D7_0610000 mitochondrial ribosomal protein L19 precursor, putative GO-0006412-translation 4999 -0.23 5.1E-06PF3D7_1228200 conserved Plasmodium protein, unknown function 5000 -0.23 6.5E-06PF3D7_0107400 conserved Plasmodium protein, unknown function GO-0006412-translation 5001 -0.23 5.1E-06PF3D7_1360000 conserved Plasmodium protein, unknown function 5002 -0.23 4.0E-06PF3D7_0106200 conserved Plasmodium protein, unknown function 5003 -0.23 3.6E-06PF3D7_1332600 apurinic/apyrimidinic endonuclease Apn1, putative GO-0006281-DNA repair 5004 -0.23 3.3E-06PF3D7_0210900 conserved Plasmodium protein, unknown function 5005 -0.23 4.2E-06PF3D7_0611600 conserved Plasmodium protein, unknown function 5006 -0.23 2.8E-06PF3D7_0731600 acyl-CoA synthetase GO-0006631-fatty acid metabolic process 5007 -0.23 2.3E-06PF3D7_1008200 endonuclease, putative GO-0006281-DNA repair 5008 -0.23 2.3E-06PF3D7_1233600 asparagine and aspartate rich protein 1 5009 -0.23 2.3E-06PF3D7_1419800 glutathione reductase 5010 -0.23 2.2E-06PF3D7_0905800 conserved Plasmodium protein, unknown function GO-0006351-transcription DNA-dependent 5011 -0.23 1.8E-06PF3D7_0819700 conserved Plasmodium protein, unknown function 5012 -0.23 1.4E-06PF3D7_0705900 ATP synthase subunit C, putative GO-0015986-ATP synthesis coupled proton transport 5013 -0.24 1.3E-06PF3D7_0812700 RNA-binding protein (U1 snRNP-like), putative 5014 -0.24 1.1E-06PF3D7_1412100 conserved Plasmodium protein, unknown function 5015 -0.24 1.1E-06PF3D7_1129100 parasitophorous vacuolar protein 1 GO-0007165-signal transduction 5016 -0.24 1.1E-06PF3D7_1417300 cysteine protease ATG4, putative GO-0015031-protein transport 5017 -0.24 1.2E-06PF3D7_0910500 DNA repair protein REV1, putative GO-0006281-DNA repair 5018 -0.24 1.1E-06PF3D7_1428500 protein kinase, putative GO-0006468-protein phosphorylation 5019 -0.24 1.0E-06PF3D7_1012000 E3 ubiquitin-protein ligase, putative GO-0006281-DNA repair 5020 -0.24 9.9E-07PF3D7_1024900 conserved Plasmodium protein, unknown function 5021 -0.24 8.9E-07PF3D7_0520600 bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] | Ap4A hydrolase 5022 -0.24 9.0E-07PF3D7_1315400 zinc finger (CCCH type) protein, putative 5023 -0.24 8.4E-07PF3D7_1018600 conserved Plasmodium protein, unknown function GO-0008033-tRNA processing 5024 -0.24 8.3E-07PF3D7_1123200 leucine-rich repeat protein 5025 -0.24 7.9E-07PF3D7_0804400 methionine aminopeptidase 1c, putative GO-0006508-proteolysis 5026 -0.24 5.7E-07PF3D7_1142000 conserved Plasmodium protein, unknown function 5027 -0.24 5.7E-07PF3D7_1033000 conserved Plasmodium protein, unknown function GO-0006817-phosphate ion transport 5028 -0.25 4.5E-07PF3D7_1365600 DNA topoisomerase VI, b subunit, putative 5029 -0.25 4.1E-07PF3D7_1001100 acyl-CoA binding protein, isoform 1, ACBP1 5030 -0.25 3.3E-07PF3D7_1253000 gametocyte erythrocyte cytosolic protein GO-0006457-protein folding 5031 -0.25 2.9E-07PF3D7_1412300 nuclear transport factor 2, putative 5032 -0.25 2.6E-07PF3D7_0823200 RNA-binding protein, putative GO-0006417-regulation of translation 5033 -0.25 2.1E-07PF3D7_0919800 TLD domain-containing protein 5034 -0.25 1.4E-07PF3D7_1439300 conserved Plasmodium protein, unknown function 5035 -0.26 1.1E-07PF3D7_1018700 conserved Plasmodium protein, unknown function 5036 -0.26 8.0E-08PF3D7_1244400 conserved Plasmodium protein, unknown function 5037 -0.26 7.0E-08PF3D7_1233700 homocysteine S-methyltransferase, putative 5038 -0.27 3.1E-08PF3D7_1431800 apyrase, putative 5039 -0.27 2.4E-08PF3D7_1010400 conserved Plasmodium protein, unknown function 5040 -0.27 4.8E-08PF3D7_1225200 conserved Plasmodium protein, unknown function GO-0006355-regulation of transcription DNA-dependent 5041 -0.27 2.3E-08PF3D7_1218300 adaptor protein subunit, putative GO-0006886-intracellular protein transport 5042 -0.27 1.9E-08PF3D7_1012800 conserved Plasmodium protein, unknown function 5043 -0.27 1.3E-08PF3D7_0702000 Plasmodium exported protein (hyp12), unknown function 5044 -0.28 9.9E-09PF3D7_1442000 ADP-ribosylation factor, putative GO-0006886-intracellular protein transport 5045 -0.28 9.7E-09PF3D7_1347200 nucleoside transporter 1 5046 -0.28 8.6E-09PF3D7_1411900 p1/s1 nuclease, putative 5047 -0.28 8.4E-09PF3D7_0617100 alpha adaptin-like protein, putative GO-0006886-intracellular protein transport 5048 -0.28 6.0E-09PF3D7_0935400 gametocyte development protein 1 5049 -0.28 3.5E-09

Page 12 of 13


Correl. Coef.

corrected p-value

PF3D7_1343600 UDP-N-acetylglucosamine pyrophosphorylase, putative 5050 -0.28 3.6E-09PF3D7_1117400 conserved Plasmodium protein, unknown function 5051 -0.28 3.5E-09PF3D7_0404800 conserved Plasmodium protein, unknown function 5052 -0.28 3.1E-09PF3D7_1108500 succinyl-CoA synthetase alpha subunit, putative GO-0006099-tricarboxylic acid cycle 5053 -0.29 2.2E-09PF3D7_0701900 Plasmodium exported protein, unknown function 5054 -0.29 1.5E-09PF3D7_0404900 6-cysteine protein 5055 -0.29 1.3E-09PF3D7_0932100 protein MAM3, putative GO-0006810-transport 5056 -0.30 6.6E-10PF3D7_1144200 conserved Plasmodium protein, unknown function 5057 -0.30 5.6E-10PF3D7_1024800 conserved Plasmodium protein, unknown function UF 5058 -0.30 4.5E-10PF3D7_0914200 phospholipid or glycerol acyltransferase, putative GO-0008152-metabolic process 5059 -0.30 3.9E-10PF3D7_0628300 choline/ethanolaminephosphotransferase, putative GO-0006629-lipid metabolic process 5060 -0.31 4.6E-11PF3D7_1429900 ATP-dependent DNA helicase, putative GO-0006260-DNA replication 5061 -0.33 1.1E-12

Page 13 of 13

Table S3 - P. falciparum homologues of ROSC protein complex

Top P. falciparum hits from the homology result output of Basic Local Alignment Tool (BLASTP®) using the reported mammalian ER complex (Menieur et al.) proteins as bait.

P. falciparum gene

Mammalian homolog Accession Max score Total score Query

cover E value Correlation score

of gene exp. to clearance half-life

Corrected p-value

PF3D7_1115600 CYPB AAA52150.1 189 189 98% 9.00E-59 0.3490058 0

PF3D7_1010700 SDF2L1 BAB18277.1 58.2 58.2 69% 2.00E-09 0.34157863 3.75E-13

PF3D7_0827900 ERp72 XP_002808883.1 234 487 87% 4.00E-69 0.23384069 1.51E-06

PF3D7_1344200 GRP170 AEX60710.1 224 224 40% 2.00E-62 0.14678577 0.003939797

PF3D7_0917900 BiP AAF13605.1 837 837 95% 0 0.14623795 0.004084432

PF3D7_1437900 ERdj3 XP_001348533.1 167 167 93% 2.00E-47 0.12203496 0.01879917

PF3D7_1222300 GRP94 NP_003290.1 527 527 92% 2.00E-173 0.09195834 0.087452072

PF3D7_1134100 CaBP1 NP_001269636.1 181 181 88% 2.00E-50 0.046945695 0.427960275

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