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TOF-PET Imaging TOF-PET Imaging t1 t2 d = c x t /2 When t = 300 ps d = 4.5 cm Timing resolution required for MPPC Timing resolution required for MPPC 200 ps PET TOF-PET

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Timing resolution required for MPPC ≤ 200 ps. ■ TOF-PET Imaging. PET. t1. t2. TOF-PET. D d = c x D t /2 When D t = 300 ps ➔ D d = 4.5 cm. C. 250 ps. D. E. E. 140 ps. C. D. Timing resolution has improved from 250 ps to 140 ps. ■ Results. Pulse intensity: 10 photons. - PowerPoint PPT Presentation

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Page 1: ■ TOF-PET Imaging

■ ■ TOF-PET ImagingTOF-PET Imaging

t1

t2

d = c x t /2When t = 300 ps ➔ d = 4.5 cm

Timing resolution required for MPPC Timing resolution required for MPPC ≤ 200 ps

PET

TOF-PET

Page 2: ■ TOF-PET Imaging

0

100

200

300

400

500

0 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5

Overvoltage (V)

FW

HM

( p

s )

■ ■ ResultsResults

High time resolution

Operating overvoltage range has expanded.Operating overvoltage range has expanded.

Pulse intensity: 10 photons

6x4 mm2, 50 m pitch: Standard MPPC: New MPPC

C

D

EC

E

D

Timing resolution has improved from 250 ps to Timing resolution has improved from 250 ps to 140 ps.140 ps.

250 ps250 ps

140 ps140 ps

Page 3: ■ TOF-PET Imaging

■ ■ SummarySummary

Standard MPPC New MPPC

Dark Count 2.7 Mcps 1.7 Mcps

After Pulses > 100% 3%

PDE 38% 43%

Overvoltage Range

1.5 ~ 2.5 V 2 ~ 3.5 V

Gain 0.8 ~ 1.2 x 106 1.1 ~ 1.4 x 106

Timing Resolution

250ps*1 140ps

Overvoltage = 2.5 V6x4 mm2, 50 m pitch

*1) overvoltage = 2.0 V

Page 4: ■ TOF-PET Imaging

■ Medical ・ PET MR-PET (Insensitive to magnetic field) TOF-PET(good timing resolution) DOI-PET(conpact)

■ Academic ・ High energy physics experiment ・ Elementary particle physics ・ Astronomy physics

■ Measurement ・ Distance measurement ・ DNA Sequencer ・ Diagnosis of blood ・ Fluorescence measurement

Applications

e+

e-

x

γ

γt1

t2 ( t2 - t1 ) ・ cX = 2

TOF-PET

DOI-PET

Page 5: ■ TOF-PET Imaging

64ch (8x8) array: C11206-0808 series

Amp circuit

HV module

S11834-3388DFdiscrete 64ch array of 3×3mm, 50μm pitch with FPC

Including ASIC(2 of 32ch preamplifier) and bias circuit for MPPC

Resistive charge division network