03-titel-2 + bold Master of Occus audit et omnisciis04-intro-zitat As aliquia natum quo ea que quiae cum rorae.

D-BIOL Symposium 2016Program and posters

Congress Center Davos, 13 - 15 June 2016

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Program Monday, June 13

11:00 – 13:00 Registration / Mounting of posters

Sandwich bar (in front of room Davos)

13:10 – 13:15 Welcome address Ruedi Aebersold, D-BIOL Chair Lecture session I Chair: Nenad Ban Room: Davos

13:15 – 14:00 Guest Lecture

Andrej Sali; University of California, San Francisco Integrative Structural Biology

14:00 – 14:25 Kaspar Locher; Institute of Molecular Biology and Biophysics

Mechanism of lipid-linked oligosaccharide flipping in protein N- glycosylation

14:25 – 14:50 Christopher Aylett; Institute of Molecular Biology and Biophysics Architecture of human mTORC1: the master regulator of translation

14:50 – 15:15 Rudolf Glockshuber; Institute of Molecular Biology and Biophysics The catch bond mechanism of the bacterial adhesin FimH and its role in urinary tract infections

15:15 – 15:45 Coffee break (in front of room Davos)

Lecture session II Chair: Anton Wutz Room: Davos

15:45 – 16:10 Gerald Schwank; Institute of Molecular Health Sciences

CRISPR in personalised medicine

16:10 – 16:35 Constance Ciaudo; Institute of Molecular Health Sciences DGCR8 protein controls the exit of pluripotency of mouse embryonic stem cells by regulating alternative splicing of Tcf7l1 mRNA

2/17

16:35 – 17:00 Markus Stoffel; Institute of Molecular Health Sciences Control of endocrine function by miRNAs

17:15 – 17:45 Poster-Flashtalks

18:00 – 20:00 Poster-Apéro (Odd numbered posters in rooms Forum, Studio, Hallway)

20:00 Dinner (Rooms Sanada and Sanada Foyer)

Tuesday, June 14

Lecture session III Chair: Olivier Voinnet Room: Davos

08:30 – 08:55 Clara Sánchez Rodríguez; Plant Sciences

Plant pathogen perception and early response

08:55 – 09:20 Antia Rodriguez-Villalon; Plant Sciences Wiring a plant: phospholipid-dependent networks controlling vascular

development

09:20 – 09:45 David Seung; Plant Sciences Novel proteins that orchestrate starch biosynthesis in plants

09:45 – 10:10 Poster-Flashtalks

10:10 – 10:40 Coffee break (in front of room Davos)

Lecture session IV Chair: Wilhelm Krek Room: Davos

10:40 – 11:25 Guest Lecture

Gisbert Schneider; D-CHAB, ETH Zurich Designing chemical probes of biological systems in machina

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11:25 – 11:50 Marc Bachofner; Institute of Molecular Health Sciences Large-Scale quantitative proteomics identifies novel regulators of liver regeneration

11:50 – 12:15 Matthias Gstaiger; Institute of Molecular Systems Biology

Cell signaling systems seen through a mass spectrometer 12:15 – 12:40 Uwe Sauer; Institute of Molecular Systems Biology

Which regulation events matter for coordination of metabolism?

12:40 – 15:30 Lunch (in front of room Davos) & break

Lecture session V Chair: Wolf-Dietrich Hardt Room: Davos

15:30 – 15:55 Orane Guillaume-Gentil; Institute of Microbiology

Non-destructive sampling and analysis of soluble molecules from single live cells

15:55 – 16:20 Markus Künzler; Institute of Microbiology Fungal warheads against bacteria and nematodes

16:20 – 16:45 Roger Geiger; Institute of Microbiology

Metabolic regulation of the T cell response 16:45 – 17:10 Roman Spörri; Institute of Microbiology

Activating dendritic cells for immunological tolerance 17:25 – 17:55 Poster-Flashtalks

18:00 – 20:00 Poster-Apéro (Even numbered posters in rooms Forum, Studio, Hallway)

20:00 Dinner (Room Davos)

4/17

Wednesday, June 15

Lecture session VI Chair: Gebhard Schertler Room: Davos

08:30 – 09:15 Guest Lecture

Jeremy Thorner; University of California, Berkeley Global Protein-Protein Interaction Capture In Situ at Endogenous Levels of Expression

09:15 – 09:40 Frédéric Allain; Institute of Molecular Biology and Biophysics

Hybrid structural approach to study protein-RNA interactions

09:40 – 10:05 Bernd Wollscheid; Institute of Molecular Systems Biology Decoding Ligand-Receptor Interactions

10:05 – 10:30 Ulrike Kutay; Institute of Biochemistry The cell nucleus: plastic, clastic and fantastic

10:30 – 11:00 Coffee break (in front of room Davos)

Lecture session VII Chair: Karsten Weis Room: Davos

11:00 – 11:25 Benoît Kornmann; Institute of Biochemistry

Next-generation yeast genomics: using transposons and sequencing to screen the yeast genome

11:25 – 11:50 Yves Barral; Institute of Biochemistry

Yeast as a model system for studying ageing

11:50 – 12:15 Paola Picotti; Institute of Biochemistry Probing protein structural changes in health and disease

Farewell

From 12:15 Dismounting of posters

Take-away sandwiches

Departure

5/17

Posters

Posters in the room "Studio"

1. Abt, Melanie (Prof. Dr. S. Zeeman), Plant Sciences Characterisation of novel proteins involved in starch metabolism in Arabidopsis

2. Affolter, Ilaria (Prof. Dr. M. Aebi), Microbiology

Analysis of N-glycan processing in ER and Golgi of CHO cells 3. Akcay, Izzet Mehmet (Prof. Dr. E. Hafen), Molecular Systems Biology

Quantitative Genetics of Drosophila Larval Starvation Resistance 4. Anjanappa, Ravi B., Plant Sciences

Metabolic engineering of carbon pathways to enhance yield of root and tuber crops

5. Antunes Pereira, Jorge Alexandre, Molecular Health Sciences

The microprocessor complex promotes Schwann cell survival during radial sorting and is required for proper myelin maintenance

6. Arter, Meret (Prof. Dr. J. Matos), Biochemistry

Regulation of crossover formation in meiosis 7. Arvaniti, Eirini (Prof. Dr. M. Claassen), Molecular Systems Biology

Sensitive detection of rare disease-associated cell subsets via representation learning

8. Assenza, Federica (Prof. Dr. S. Zeeman), Plant Sciences

Shedding light on the nuclear β-amylases signaling pathway in Arabidopsis thaliana

9. Bammert, Lukas (Prof. Dr. U. Kutay), Biochemistry

AATF forms a nucleolar protein complex with NGDN and NOL10 required for 40S ribosomal subunit synthesis

10. Banaei Esfahani, Amir (Prof. Dr. R. Aebersold), Molecular Systems Biology

Quantitative proteome analyses of diverse Mycobacterium tuberculosis clinical isolate strains

11. Barnstorf, Isabel (Prof. Dr. A. Oxenius), Microbiology

Tuning of immune homeostasis and immune responsiveness by persistent viral infections

12. Basan, Markus, Molecular Systems Biology

A metabolic tradeoff between fast growth and rapid adaptation

6/17

13. Beusch, Irene (Prof. Dr. F. Allain), Molecular Biology and Biophysics Exploration of MBNL1 RNA Binding

14. Bieri, Philipp (Prof. Dr. N. Ban), Molecular Biology and Biophysics

The Complete Structure of the 55S Mammalian Mitochondrial Ribosome 15. Bindszus, Mareike (Prof. Dr. M. Kopf, Dr. J. Kisielow), Molecular Health Sciences

IL-36 cytokines in fungal infections 16. Blattmann, Peter, Molecular Systems Biology

Targeted mass spectrometric analysis of the cellular response to the perturbations of the LXR and SREBP pathway

17. Bloch, Joël (Prof. Dr. K. Locher), Molecular Biology and Biophysics

Structural Studies of the Human Transcobalamin Receptor CD320 18. Bludau, Isabell (Prof. Dr. R. Aebersold), Molecular Systems Biology

Advanced workflows and concepts for the analysis of high throughput targeted proteomics experiments of large heterogeneous datasets

19. Böck, Desirée Anette (Prof. Dr. M. Pilhofer), Molecular Biology and Biophysics

In situ imaging of bacterium-host interactions 20. Bologna, Nicolas, Plant Sciences

Nuclear localization of At-AGO1 21. Borsa, Mariana (Prof. Dr. A. Oxenius), Microbiology

Asymmetric Cell Division and Barrier Function in T cell Fate Determination 22. Brachmann, Alexander Oliver, Microbiology

Colibactin biosynthesis and biological activity depend on the rare aminomalonyl polyketide precursor

23. Cahn, Jackson, Microbiology

Toward heterologous expression of natural product biosythetic pathways from sponge symbionts

24. Calpe, Blaise (Prof. Dr. W. Krek), Molecular Health Sciences

3D cancer microtissue high content screening to identify hypoxia-induced vulnerabilities

25. Cangrama, Michael and Wietecha, Mateusz, Molecular Health Sciences

Effect of Activin A on the transcriptome and function or macrophages and fibroblasts during tumorigenesis and healing in the skin

26. Cannac, Fabien (Prof. Dr. V. Korkhov), Structural Biology (PSI) / Biochemistry

Functional and structural analyses of receptor guanylyl cyclases 27. Carrera, Dániel Árpád (Dr. S. Streb, Prof. Dr. S. Zeeman), Plant Sciences

New insights into the metabolism of photosynthesis in Arabidopsis thaliana 28. Castelo Dias Cruz, Tiago Miguel (Prof. Dr. A. Rodriguez-Villalon), Plant Sciences

Molecular characterization of downstream targets of phosphoinositides singling pathway

7/17

29. Cereghetti, Gea and Saad, Shady (Prof. Dr. M. Peter), Biochemistry Reversible aggregation of Cdc19 regulates cell cycle restart after stress

30. Champion, Lysie Sylviane (Prof. Dr. U. Kutay), Biochemistry

Constitutive NE-chromatin tethering reveals the requirement of membrane clearance from chromatin for chromosome condensation and segregation

31. Chen, Xiuzhen (Prof. Dr. Y. Barral), Biochemistry

Control of astral microtubule length in S. cerevisiae: All About Balance 32. Chevalier, Clement, Plant Sciences

eIF4a1, an AGO1 cofactor required for translational repression in plant RNA silencing

33. Christen, Matthias, Molecular Systems Biology

Genome Calligrapher: A web-tool for refactoring bacterial genomes for de novo DNA synthesis

34. Christodoulou, Dimitrios (Prof. Dr. U. Sauer), Molecular Systems Biology

A kinetic model describes the metabolic response of E. coli to oxidative stress 35. Cirera Salinas, Daniel, Molecular Health Sciences

Deciphering new miRNA biogenesis pathway modulators by CRISPR/Cas9 screens

36. Cornillie, Nathalie (Prof. Dr. M. Aebi), Microbiology

Characterization of the Entamoeba histolytica oligosaccharyltranserase 37. Couzigou, Jean-Malo, Microbiology

Bacterial control of nodule-to-root conversion in soybean 38. da Graça Gilberto, Samuel Filipe (Prof. Dr. M. Peter), Biochemistry

Cullin-4B phosphorylation in the regulation of cell cycle progression 39. David, Laure, Plant Sciences

Starch remobilization in Cassava roots 40. Dechant, Reinhard Christoph, Biochemistry

Cytosolic pH regulates cell growth by promoting mTORC1 activity 41. Dedic, Emil, Molecular Biology and Biophysics

Structural characterization of the hnRNP C tetramer and the bZIP-like RNA binding domain

42. Del Medico, Luca (Prof. Dr. B. Christen), Molecular Systems Biology

Insights into the temperature dependency of bacterial core networks 43. Denzler, Rémy, Molecular Health Sciences

Impact of miRNA Levels, Target-Site Complementarity and Cooperativity on ceRNA-Regulated Gene Expression

44. Devers, Emanuel, Plant Sciences

Direct evidence for plasmodesmata-mediated cell-cell and long distance movement of plant siRNA

8/17

45. Di Minin, Giulio, Molecular Health Sciences A forward genetic approach to identify new modulators of Hedgehog signaling in haploid ES cells

Posters in the room "Forum"

46. Diethelm, Patrizia (Prof. Dr. M. Kopf), Molecular Health Sciences

Regulation and function of BTLA and HVEM during a viral infection 47. Diether, Maren (Prof. Dr. U. Sauer), Molecular Systems Biology

The role of Nitrogen Network Kinase 1 in the regulation of yeast metabolic enzymes and TORC1 signaling

48. Dimas, Penelope (Prof. Dr. U. Suter), Molecular Health Sciences

De novo fatty acid synthesis in oligodendrocyte progenitors is critical for efficient CNS remyelination

49. Dintner, Sebastian (Prof. Dr. J. Vorholt), Microbiology

Signaling in the General Stress Response of Sphingomonas melonis FR1 50. Domínguez Sánchez, Jesús María (Prof. Dr. W. Krek), Molecular Health Sciences

Role of splicing kinase Clk3 in Hif1α driven cardiac hypertrophy 51. Dorn, Georg (Prof. Dr. F. Allain), Molecular Biology and Biophysics

High-resolution mapping of protein-RNA interactions by crosslinking of segmentally isotope-labelled RNA and LC-MS/MS

52. Duda, Heike (Prof. Dr. J. Matos), Biochemistry

Make it or break it - A mechanism for controlled breakage of under-replicated chromosomes in mitosis

53. Echevarría-Zomeño, Sira, Plant Sciences

Diurnal changes in the Arabidopsis thaliana proteome and phosphoproteome 54. Emurla, Hyuliya (Prof. Dr. A. Oxenius), Microbiology

Asymmetric cell division and barrier function in T cell fate determination 55. Eyring, Jillianne (Prof. Dr. M. Aebi), Microbiology

Characterization of the Octameric Oligosaccharyltransferase from Saccharomyces cerevisiae

56. Faini, Marco, Molecular Systems Biology

Structural restraints on protein complexes from human cells by affinity purification cross-linking MS

57. Falke, Martin (Prof. Dr. J. Jiricny), Molecular Cancer Research (UZH)

Usage of 2nd generation protein replacement system to study MLH1 missense mutations

9/17

58. Feng, Yuehan (Prof. Dr. P. Picotti), Biochemistry In vivo Structural Snapshots of a Protein Chameleon

59. Feng-Jurgeit, Qian and Helle, Sebastian (Prof. Dr. B. Kornmann), Biochemistry

The Force Awakens: Mechano-Induced Mitochondrial Fission 60. Figlia, Gianluca (Prof. Dr. U. Suter), Molecular Health Sciences

Same pathway, opposing effects: the Akt-mTORC1 axis inhibits the onset of myelination, but promotes myelin growth

61. Fischer, Elisabeth Julia (Dr. H. Stocker), Molecular Systems Biology

Contribution of Apoptosis to the Overgrowth of PTEN Mutant Tissue Under Nutrient Restriction in Drosophila

62. Fowler, Kyle (Prof. Dr. F. Allain), Molecular Biology and Biophysics

Structural investigation of the role in RNA recognition of SRSF1 and SRSF5 canonical RRMs

63. Friedrich, Betty (Prof. Dr. R. Aebersold), Molecular Systems Biology

Proteomic characterization of homologous recombination deficiency in ovarian cancer

64. Frischer, Katharina (Prof. Dr. U. Kutay) Biochemistry

LINC complex dynamics in vivo – Studying SUN-KASH interaction by FRET 65. Fuchs, Sebastian Winfried, Microbiology

Influence of the proteusin leader peptide on the activity of radical S-adenosylmethionine epimerases

66. Furter, Markus (Prof. Dr. W.-D. Hardt), Microbiology

Structure and function of the intestinal mucus barrier in Salmonella Typhimurium infection

67. Fütterer, Johannes, Plant Sciences

Hypervariable genes in higher eukaryonts 68. Gasser, Emanuel, Molecular Health Sciences

Foxa1 is essential for development and functional integrity of the subthalamic nucleus

69. George, Gavin, Plant Sciences

How alterations in carbon metabolism influence growth: a cross species analysis 70. Gerhardy, Stefan (Prof. Dr. V. Panse), Biochemistry

Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation

71. Giese, Christoph, Molecular Biology and Biophysics

Engineering the most stable protein-ligand complex towards faster association 72. Giovannini, Sara, Molecular Cancer Research (UZH)

Characterization of the role of ATAD5 in human cells 73. Graeber, Elisabeth (Prof. Dr. V. Korkhov), Structural Biology (PSI) / Biochemistry

Structural and Functional Studies of the Translocator Protein

10/17

74. Gruhl, Thomas (Prof. Dr. G. Schertler), Structural Biology (PSI) Towards the study of the ultrafast rhodopsin photoactivation process using serial femtosecond crystallography

75. Guillaume-Gentil, Orane, Microbiology

Molecular extraction and analysis of single live cells using fluidic force microscopy

76. Hartl, Johannes (Prof. Dr. J. Vorholt), Microbiology

Global analysis of coenzyme turnover and homeostasis in microorganisms 77. Hausmann, Annika (Prof. Dr. W.-D. Hardt), Microbiology

NF-kB signaling in the gut mucosa 78. Heinrich, Stephanie, Biochemistry

Analysis of nuclear mRNA export in vivo in single yeast cells 79. Herrmanns, Karolin (Prof. Dr. M. Stoffel), Molecular Health Sciences

Role of miR-802 in Diabetes 80. Heusel, Moritz (Prof. Dr. R. Aebersold), Molecular Systems Biology

Assessing proteome organization by native SEC coupled to SWATH-MS 81. Hiebert, Paul, Molecular Health Sciences

Nrf2 as a mediator of fibroblast function during homeostasis and wound healing 82. Hondele, Maria, Biochemistry

The ATP-state of the DEAD-box ATPase Dhh1 regulates P-body formation in yeast 83. Isenmann, Luca (Prof. Dr. G. Schwank), Molecular Health Sciences

A novel recombinant hydrogel for organoid culture 84. John Peter, Arun and Petrungaro, Carmelina (Prof. Dr. B. Kornmann), Biochemistry

A novel tool to monitor lipid flux in space and time 85. Kastanaki, Elizabeth (Prof. Dr. A. Rodriguez-Villalon), Plant Sciences

Analysis of phosphoinositide involvement in shaping different aspects of vascular formation in Arabidopsis thaliana

86. Kiefer, Patrick, Microbiology

DynaMet, a fully automated pipeline for dynamic labeling LC-MS data 87. Kobayashi, Saho, Molecular Cancer Research (UZH)

Investigation of non-canonical role of mismatch repair protein MLH1 in chicken B cell

88. Kobayashi, Shunsuke, Molecular Cancer Research (UZH)

Investigation of FAN1 role in Interstrand crosslink repair 89. Kochanowski, Karl (Prof. Dr. U. Sauer) Molecular Systems Biology

Coordination of metabolic pathways by ballpark regulation in Escherichia coli 90. Köhler, Mario (Prof. Dr. U. Kutay), Biochemistry

Mitotic Disassembly of the Nuclear Pore Complex

11/17

Posters in the room "Hallway"

91. Köhler, Katja, Molecular Systems Biology

CAL - The Center for Active Learning at the Department of Biology 92. Kötemann, Anika (Prof. Dr. B. Wollscheid), Molecular Systems Biology

Decoding the quantitative apicobasal surfaceome of epithelia to characterize bipolar functional signaling capacities

93. Kräutler, Nike, Microbiology

Evolution of virus-specific antibodies in acute and chronic infections 94. Kruitwagen, Tom (Prof. Dr. Y. Barral), Biochemistry

Segregation of chromosomal and non-chromosomal DNA 95. Krznar, Petra (Dr. N. Zamboni, Prof. Dr. U. Sauer), Molecular Systems Biology

Experimental charting of human genome-metabolism interactions 96. Krzyzanowski, Marek Konrad (Prof. Dr. Y. Barral), Biochemistry

Protein aggregation: consequences for memory and aging 97. Kühne, Andreas (Dr. N. Zamboni, Prof. Dr. U. Sauer), Molecular Systems Biology

An integrative metabolomics and transcriptomics approach to elucidate the functional role of metabolism during skin cell differentiation

98. Lampert, Fabienne, Biochemistry

Analysis of dynamic cullin-RING ligase function by single-molecule microscopy 99. LaPierre, Mary (Prof. Dr. M. Stoffel), Molecular Health Sciences

MicroRNA-7 regulates pituitary function and fertility 100. Lehmann, Elisabeth, Molecular Biology and Biophysics

Molecular basis of RNA-dependent multimerisation of hnRNP A1 101. Lesca, Elena et al., Structural Biology (PSI)

Prowl, prance and prey: a tale of bistability in jumping spider rhodopsin 102. Leuenberger, Pascal (Prof. Dr. P. Picotti), Biochemistry

Global Profiling of Thermodynamic Protein Stability on a sub-Protein Level 103. Lin, Chia-wei (Prof. Dr. M. Aebi), Microbiology

Supercharging reagent for enhanced liquid chromatographic separation and charging of sialylated and large glycopeptides for nanoHPLC-ESI-MS/MS analysis

104. Losfeld, Marie-Estelle, Microbiology

N-glycoprotein: role of protein structure on glycan microheterogeneity 105. Maciejewska-Rodrigues, Hanna, Microbiology

Coupling growth and succinate production through multiple gene deletions in Escherichia coli

12/17

106. Macnair, Will (Prof. Dr. M. Claassen), Molecular Systems Biology Identifying bifurcations in single cell data

107. Maddaluno, Luigi, Molecular Health Sciences

Fibroblast growth factors inhibit interferon signaling and promote viral replication through a novel p38-Rac1-IRF7 signaling pathway

108. Markolin, Philipp (Prof. Dr. W. Krek), Molecular Health Sciences

Decoding hypoxia-dependent SF3b1 splicing in pancreatic cancer 109. Mateescu, Bogdan, Plant Sciences

Genetic models for investigating extracellular RNAs 110. Mathew, Corina (Prof. Dr. M. Aebi), Microbiology

Site specific N-glycosylation in the ER and Golgi 111. Matkovic, Milos (Prof. Dr. G. Schertler, Dr. X. Deupi), Structural Biology (PSI)

Molecular basis of biased signaling in the angiotensin II type 1 receptor 112. McCallum, Emily, Plant Sciences

Development of herbicide-tolerant cassava using random mutagenesis 113. Mehnert, Martin, Molecular Systems Biology

Differential interaction proteomics: effect of cancer mutations on the interactome of a CMGC kinase complex

114. Mira Rocha Sabino, Fábio (Prof. Dr. S. Werner, PD Dr. U. Auf dem Keller), Molecular

Health Sciences Degradomics Analysis of Wound Exudates

115. Mishra, Ranjan (Prof. Dr. Matthias Peter), Biochemistry

Exploring yeast signaling networks sensing mechano-stress using a novel microfluidics device

116. Mittelviefhaus, Max (Prof. Dr. J. Vorholt), Microbiology

Colloidal Single-Cell Force Spectroscopy of Leaf-Bacteria Interactions 117. Monfort Pineda, Asun, Molecular Health Sciences

Identification of Crucial Factors for Xist Function through Forward Genetic Screening in Haploid Embryonic Stem Cells

118. Montani, Laura, Molecular Health Sciences

De novo fatty acid synthesis drives the onset of peripheral nervous system myelination

119. Müller, Andreas (Prof. Dr. E. Weber-Ban), Molecular Biology and Biophysics

Functional Characterization of Actinobacterial Genes Associated with the Pup-Proteasome Locus

120. Müller, Daniel Bastian (Prof. Dr. J. Vorholt), Microbiology

Microbial life on plants: Microbiota composition, colonization strategies and plant benefits

13/17

121. Müller, Maik (Prof. Dr. B. Wollscheid), Molecular Systems Biology Direct identification of lateral protein interactions in the plasma membrane of living cells using singulet oxygen generators

122. Muri, Jonathan (Prof. Dr. M. Kopf), Molecular Health Sciences

Thioredoxin reductase-1 is essential for the development and proliferation of T cells

123. Muzumdar, Sukalp (PD Dr. M. Schäfer, Prof. Dr. S. Werner), Molecular Health Sciences

Nrf2 activation promotes cutaneous wound healing by expansion of hair follicle stem cells

124. Napiórkowska, Maja Hanna (Prof. Dr. K. Locher), Molecular Biology and Biophysics

Structural and functional studies of the bacterial N-oligosaccharyltransferase PglB in complex with an acceptor peptide and a donor lipidlinked oligosaccharide

125. Ngondo, Richard Patryk, Molecular Health Sciences

Ago2 is important for primitive endoderm differentiation 126. Nguyen, Bidong, Microbiology

Signature Tag Mutagenesis Screen for Colonization, Growth, and Virulence Determinants of Salmonella enterica Typhimurium in the Mouse Infection Model by Quantitative Transposon Sequencing

127. Nikolaev, Yaroslav, Molecular Biology and Biophysics

NMR spectroscopy in Systems Biology applications 128. Noor, Elad, Molecular Systems Biology

The enzyme cost of metabolic flux: a case for substrate channeling 129. Obbineni, Jagan Mohan (Prof. Dr. T. Ishikawa), Structural Biology (PSI)

Understanding the Bending Mechanism of Eukaryotic Flagella using Cryo-electron Microscopy

130. Oberlin, Stefan (Prof. Dr. O. Voinnet), Plant Sciences

Competition between RNA quality control and the silencing machinery explains how transposons in Arabidopsis thaliana are initially recognized

131. Ochsner, Andrea (Prof. Dr. J. Vorholt), Microbiology

Identification of Novel Genes Involved in Methylotrophy Using a Hyper-Saturated Transposon Screen

132. Okada,Hirokazu, Molecular Systems Biology

Proteome-wide association studies identify biochemical modules associated with a wing size phenotype in Drosophila melanogaster

133. Okreglicka, Katarzyna Maria (Prof. Dr. M. Kopf), Molecular Health Sciences

Peroxisome proliferator-activated receptor gamma (PPARg) plays a crucial role in the red pulp macrophage development

134. Onishchenko, Evgeny, Biochemistry

Natively unfolded FG-repeats stabilize the structure of the nuclear pore complex

14/17

135. Orlando, Eleonora (Dr. Y. Zimmer, Prof. Dr. R. Aebersold), Molecular Systems Biology The role of MET in tumor resistance to radiation therapy: a phosphoproteomic approach

136. Pallmer, Katharina (Prof. Dr. A. Oxenius), Microbiology

NCR1-Ligand interaction in the cross-talk between NK and T cells 137. Panneels, Valérie et al., Structural Biology (PSI)

Towards retina connectome X-ray imaging at the synaptic level for analysing the rescuing effects of optogenetics on neurons degeneration

138. Parniewska, Malgorzata (Dr. H. Stocker), Molecular Systems Biology

Identifying regulators and effectors of TORC1 activity necessary for the proliferative potential of PTEN mutant cells under nutrient restriction

139. Pawar, Sumit (Prof. Dr. U. Kutay), Biochemistry

ER connectivity plays a key role in nuclear targeting of membrane proteins 140. Pentz, Richard (Prof. Dr. C. Azzalin), Biochemistry

Requirement of FANCM for ALT cell proliferation constitutes a novel ALT-specific vulnerability

141. Peterka, Martin (Prof. Dr. B. Kornmann), Biochemistry

Interrogating mitochondrial CENP-F in vitro and in vivo 142. Peters, Eike Edzard (Prof. Dr. J. Piel), Microbiology

Exploring the uncultivated - FISHing for natural product producers in marine sponges

143. Poghosyan, Emiliya (Prof. Dr. T. Ishikawa), Structural Biology (PSI)

The Radial Spoke Proteins of motile cilia and flagella 144. Poljak, Kristina (Prof. Dr. M. Aebi), Microbiology

Parallel Reaction Monitoring - Based Quantification of Site Specific N-Glycosylation Occupancy in Yeast Saccharomyces cerevisiae

145. Postlmayr, Andreas (Prof. Dr. A. Wutz), Molecular Health Sciences

The Impact of Cdk8 on X-Chromosome Inactivation 146. Prasad, Rupali, Biochemistry

Sphinoglipids restrict the diffusion of membrane proteins during mitosis in Saccharomyces cerevisiae

147. Qi, Chao (Prof. Dr. V. Korkhov), Structural Biology (PSI) / Biochemistry

Structure and function research of Mammalian Adenylyl Cyclase 148. Rajoo, Sasikumar (Prof. Dr. K. Weis), Biochemistry

Deciphering yeast nucleoporin stoichiometry using fluorescence approaches 149. Renz, Peter and Panagiota Tsikrika (Prof. Dr. A. Wutz), Molecular Health Sciences

Dissecting Signaling Pathways in Human Embryonic Stem Cells 150. Ringel, Till (Prof. Dr. G. Schwank), Molecular Health Sciences

Systematic Mapping of Tumor Driver Genes to Stem Cell Signaling Pathways

15/17

151. Rubini, Marina, Molecular Biology and Biophysics Why is there no strict selection for fast protein folding?

152. Ruiz Sola, M. Águila, Plant Sciences

Investigating the function of the Arabidopsis OCTOPUS gene family in phloem development

153. Sachdev, Ruchika, Biochemistry

Signaling events regulating the formation of cytoplasmic mRNP granules (P bodies) in yeast

154. Salmon, Loic, Molecular Biology and Biophysics

Structural Changes Mediating Catalytic Processes in pRN1 DNA Primase 155. Sandu, Ioana (Prof. Dr. M. Claassen, Prof. Dr. A. Oxenius), Molecular Systems Biology

An in vivo model for T cell exhaustion 156. Schreier, Tina (Prof. Dr. S. Zeeman, Dr. O. Kötting), Plant Sciences

Investigating the plastidial malate dehydrogenase in complex with starch degradation-related proteins

157. Sengör, Asim (Prof. Dr. Y. Barral), Biochemistry

Protein aggregation: consequences for memory and aging 158. Shao, Wenguang, Molecular Systems Biology

Investigating the basic assumptions in protein abundance estimation using SWATH-MS data -- an improved understanding of protein quantity inference

159. Sidler, Corinne, Biochemistry

Altered telomere transcription during establishment of replicative and progerin-induced senescence in human primary fibroblasts

160. Siegenthaler, Beat (Prof. Dr. S. Werner), Molecular Health Sciences

The role of Nrf3 in skin homeostasis and disease 161. Sliwa-Gonzalez, Andrzej (Prof. Dr. Y. Barral), Biochemistry

Lateral compartmentalisation of the budding yeast nucleus 162. Soste, Martin, Biochemistry

Identification of cellular pathways that predict rescue across modulators of alpha-synuclein toxicity

163. Stark, Rebekka (Prof. Dr. W. Krek), Molecular Health Sciences

A kinome-scale synthetic lethality screen in cancer cells with 19q12 amplification 164. Susperregui Iriondo, Aitor (Prof. Dr. J. Matos), Biochemistry

Identification and characterization of novel regulators of recombinational DNA repair during mitosis and meiosis

165. Svozil, Julia, Plant Sciences

Uncover the mode of action of cis-NATs as translation enhancers 166. Tang, Guanghui (Prof. Dr. W. Krek), Molecular Health Sciences

Roles of fructose diet in pancreatic cancer

16/17

167. Title, Alexandra (Prof. Dr. M. Stoffel), Molecular Health Sciences The role of miR-200 in insulinoma progression and metastasis

168. Tschopp, Marie-Aude, Plant Sciences

Identification of a double-stranded RNA binding complex, which modulates processing by RNaseIII enzymes

169. Ueoka, Reiko, Microbiology

Novel trans-AT polyketides from Methylobacterium extorquens AM1 170. Uliana, Federico (Dr. M. Gstaiger, Prof. Dr. R. Aebersold), Molecular Systems Biology

A new approach to study pathogenesis of fibrosis: Analysis of the YAP1 interactome

171. van Leeuwen, Daniël (Dr. B. Mateescu, Prof. Dr. O. Voinnet), Plant Sciences

The cell biology of long dsRNA silencing in mammalian cells 172. Vercellino, Irene (Prof. Dr. V. Korkhov), Structural Biology (PSI) / Biochemistry

Structural studies of Adenylyl Cyclase 173. Weber, Carmen (Prof. Dr. K. Weis), Biochemistry

How do yeast respond to Glucose starvation? 174. Weiss, Gregor (Prof. Dr. M. Pilhofer), Molecular Biology and Biophysics

Characterization of a novel Type VI-like Secretion System in Bacteroidetes 175. Welten, Suzanne, Microbiology

Tuning of pathogen-specific immune responses by infection induced inflammation 176. Wetter, Emma Marie Caroline, Microbiology

IgA-mediated "caged growth" directs intestinal bacterial population dynamics and within-host evolution

177. Winkler, Martin (Prof. Dr. M. Peter), Biochemistry

Structural and kinetic analysis of CSN activation and the cullin-RING ubiquitin ligase deneddylation cycle

178. Wolf, Tobias (Prof. Dr. A. Lanzavecchia), Molecular Health Sciences

Naive T cells maintain idle ribosomes, mRNAs, and glycolytic enzymes to jump-start activation

179. Wotzka, Sandra Yvonne (Prof. Dr. W.-D. Hardt), Microbiology

Probing colonization resistance against Salmonella Typhimurium 180. Wu, Ting-Ying (Dr. N. K. Bhullar, Prof. Dr. W. Gruissem), Plant Sciences

Novel Strategies for Iron Biofortification of Rice with Focus on Iron trafficking in Grain

181. Xue, Jing (Prof. Dr. M. Stoffel), Molecular Health Sciences

A new role of cyclin-dependent kinase 8 in the regulation of insulin secretion from pancreatic β-cells

182. Yilmaz, Vural, (Dr. R. Spörri, Prof. Dr. A. Oxenius), Microbiology

Differential Requirement for Direct Pattern Recognition in Vaccination versus Immunity to Infection

17/17

183. Zach, Christina (Prof. Dr. M. Aebi), Microbiology Dissecting the biosynthetic pathway of O-methylated N-glycans in Caenorhabditis elegans

184. Zhu, Yi, Molecular Systems Biology

High-throughput proteome digitalization of biopsy-level formalin-fixed paraffin-embedded (FFPE) samples

185. Ziemski, Michal (Prof. Dr. E. Weber-Ban), Molecular Biology and Biophysics

Identification of novel Pup-proteasome system molecular partners 186. Ziltener, Pascal, Microbiology

TNF-dependent alveolar macrophage and ROS-dependent neutrophil mediated mechanisms control Legionella pneumophila Lung infection

187. Zyla, Dawid (Prof. Dr. R. Glockshuber), Molecular Biology and Biophysics

The bacterial pilus subunit FimA: A unique case of a protein with alternative folding possibilities