04 university campus suffolk ipswich, united kingdom · attend the 8th international workshop on...
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04th-07th May 2012University CaMpUs sUffolk ipswiCh, United kingdoM
organized by:
executive Chairmen:
in cooperation with:
ISMNIDieter Felsenberg, Berlin germany Eckhard Schönau, Cologne germany
international society forMusculoskeletal & neuronal interaction
in Cooperation with german society for Muscle-and Bone research, Zentrum für Muskel- und knochenforschung - Charité - Universitätsmedizin Berlin, klinikum der Universität zu köln - klinik und poliklinik für kinderheilkunde
Visit us at: www.ismni.org
8th InternatIonal WorkshopFor Musculoskeletal & neuronal InteractIons
prograM
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04th-07th May 2012University CaMpUs sUffolk ipswiCh, United kingdoM
Bonviva® 150 mg Filmtabletten / Bonviva® 3 mg Injektionslösung. Zusammensetzung Filmtablette: Wirk-stoff: 150 mg Ibandronsäure (als Mononatriumibandronat 1 H2O). Sonstige Bestandteile: Tablettenkern: Lactose-Monohydrat, Povi-don, Mikrokristalline Cellulose, Crospovidon, Stearinsäure, Hochdisperses Siliciumdioxid. Tablettenhülle: Hypromellose, Titandioxid, Talkum, Macrogol 6000. Zusammensetzung Injektionslösung: Wirkstoff: 3 mg Ibandronsäure (als Mononatriumibandronat 1 H2O). Sonstige Bestandteile: Natriumchlorid, Eisessig, Natriumacetat 3 H2O, Wasser für Injektionszwecke. Anwendungsgebiet: Therapie der Osteoporose bei postmenopausalen Frauen mit erhöhtem Frakturrisiko. Eine Abnahme an Lendenwirbelbrüchen wurde gezeigt, eine Wirksamkeit hinsichtlich Oberschenkelhalsfrakturen ist nicht ermittelt worden. Gegenanzeigen: Hypokalzämie, Überempfindlichkeit gegen Ibandronsäure oder einen der sonstigen Bestandteile. Schwangerschaft und Stillzeit. Kinder und Jugend-liche. Besondere Warnhinweise und Vorsichtsmaßnahmen für die Anwendung: Nierenprobleme, Störungen des Mi-neralstoffwechsels. Über Kieferknochennekrosen unter Bisphosphonaten wurde berichtet; invasive zahnärztliche Maßnahmen nach Möglichkeit vermeiden. Filmtablette: Probleme mit der Speiseröhre oder nicht in der Lage sein 1 Stunde lang zu stehen oder auf-recht zu sitzen. Enthält Lactose. Injektionslösung: Möglichst begleitende Einnahme von Calcium- und Vitamin-D-Präparaten. Nebenwirkungen: Häufig: Sodbrennen, Durchfall, Bauchschmerzen, Übelkeit, Kopfschmerzen, Hautausschlag, Schmerzen in
Muskeln und Gelenken, grippeähnliche Symptome, Müdigkeit. Selten: Schwellungen von Gesicht, Lippen und Mund. Filmtab-lette: Häufig: Magenverstimmung, Muskelkrämpfe. Bonviva kann die Speiseröhre reizen (normalerweise nicht, wenn Einnahme gemäß Gebrauchsinformation). Symptome wie starke Schmerzen im Brustkorb, starke Schmerzen beim Schlucken von Speisen oder Getränken, starke Übelkeit oder Erbrechen, sind sofort dem Arzt mitzuteilen. Gelegentlich: Schwindel, Rückenschmerzen, Blähungen. Selten: Jucken von Gesicht, Lippen und Mund. Injektionslösung: Abfall des Calcium-Spiegels im Blut. Häufig tre-ten innerhalb eines Tages nach der ersten Injektion Beschwerden oder Schmerzen in den Muskeln, Knochen oder Gelenken oder Fieber, Schüttelfrost oder Fieberhaftigkeit auf. Meist leichte Symptome, die keiner Behandlung bedurften und schnell vorüber-gehen sollten (innerhalb von 2–3 Tagen nach der Injektion) und normalerweise nach der zweiten Injektion nicht mehr auftreten. Wenn sie nach der zweiten Injektion auftreten, sind sie gewöhnlich schwächer und verschwinden nach der dritten oder nach weite-ren Injektionen ganz. Häufig: Verstopfung, Rückenschmerzen. Gelegentlich: Hautreaktionen an der Injektionsstelle (Rötung, Schmer-zen und Schwellungen), Knochenschmerzen, Schmerzen, Rötung und Schwellung der Venen. Verschreibungspflichtig. Stand der Information: Juli 2009 PHARMAZEUTISCHER UNTERNEHMER: Roche Registration Limited, 6 Falcon Way, Shire Park, Welwyn Garden City, AL7 1TW, Vereinigtes Königreich. Vertreter in Deutschland: Roche Pharma AG, 79630 Grenzach-Wyhlen
… am Knochen. … bei Ihrer Patientin. … in Ihrer Praxis.
Bonviva® i.v.Kommt einfach gut an
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04th-07th May 20128th international workshop
for MUsCUloskeletal & neUronal interaCtions
invitation Dear colleagues,
on behalf of the organizing committee chaired by prof. Dieter Felsenberg and prof. eckhard schönau we have the great pleasure to invite you to attend the 8th International Workshop on Musculoskeletal and neuronal Interactions. the meeting will take place between 4-7 May 2012 at the “unversity campus suffolk in Ipswich, uk”.
It´s organized by the International society of Musculoskeletal and neuronal Interactions (IsMnI), a non profit scientific society whose mission is to enhance the knowledge of the interactions between tissues and organs involved in the function of the musculoskeletal system.
emphasis is mainly given to the interactions of bones, joints, muscles and the neuronal system. IsMnI seeks to link multiple disciplines in promoting a broader understanding of the physiology of the musculoskeletal and neural systems and the clinical applications of their interactions, mainly loading and exercise.
We look forward to welcoming you to the 8th IsMnI meeting in May 2012
Dieter Felsenberg eckhard schönau president IsMnI Meeting co-chair
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04th-07th May 2012University CaMpUs sUffolk ipswiCh, United kingdoM
Program Committee:
Jörn rittweger, Frank rauch, pepe Ferretti, Webster Jee, Jean-pierre Devogelaer,
hans Degens, rainer rawer, oliver semler, oliver Bock, Yannis Dionyssiotis
Steering Committee:
eckhard schönau, Jürg gasser, george lyritis, Dieter Felsenberg, Brendon noble
Meeting Co-chairs:
eckhard schönau
Local Organising Committee
Brendon noble
university campus suffolk, school of health, science center & social care,
Waterfront Building, 19 neptune Quay, Ipswich Ip4 1QJ
unIteD kIngDoM
Conference Location:
university campus suffolk
Waterfront Bldg 19 neptune Quay,
IpsWIch, suffolk Ip4 1QJ
unIteD kIngDoM
Congress Organisation, Registration,
Exhibition & Sponsoring
medical event solutions gmbh
Mrs. Yvonne Beetz
Bahnhofstr. 48
D-12305 Berlin
gerManY
tel. +49 (0) 30/ 700 789 50
Fax: +49 (0) 30 / 700 789 5111
email: [email protected]
www.mes-berlin.com
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04th-07th May 20128th international workshop
for MUsCUloskeletal & neUronal interaCtions
Friday, May 4th
13:00 Welcome (Dieter Felsenberg, eckard schönau)
13:15 session 1 Muscle BIologY, FunctIon anD assessMent (chair: george lyritis)
13:15 limits to muscle plasticity (hans Degens)
13:50 propaedeuticum: Mechanics of muscle function (hans schießl)
14:30 Coffee break
15:00 session 2 agIng Muscle (chair: hans Degens)
15:00 Muscle adaptation and Muscle aging (Marco toigo)
15:45 sarcopenia and assessment of Muscle Function (Martin runge)
16:15 Free communications - abstracts 05, 20 & 07
16:45 Short Break
17:00 session 3 prIncIples oF Bone BIologY (chair: Frank rauch)
17:00 Bone cells and signaling pathways (erik Fink eriksen)
17:30 genetics of biology and skeletal diseases (Barbara obermayer-pietsch)
18:00 changes in bone from the cradle to the grave (Frank rauch)
18:30 Welcome Reception at UCS
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04th-07th May 2012University CaMpUs sUffolk ipswiCh, United kingdoM
Saturday, May 5th
09:00 session 4 MechanIcs oF Bone (chair: Yannis Dionyssiotis)
09:00 principles of mechanics (hans schießl)
09:30 Mechanobiology (Franz Jakob)
10:00 the Importance of Being cortical (José Ferretti)
10:30 Coffee break
10:50 session 5 Muscle anD Bone InteractIon (chair: Jörn rittweger)
10:50 Muscle and bone in immobilization/weightlessness (Daniel Belavy)
11:20 countermeasures of muscle wasting: does bone reap some benefits? (Jörn rittweger)
11:50 Free communications - abstracts 15, 29, 02 & 26
12:30 Lunch
13:15 Workshop on Mechanography organized by rainer rawer.
13:15 Muscle density, a surrogate of intermuscular adiposity, derived from pQct is an independent correlate of fractures in women. (andy Wong)
13:25 recommendations for the usage of reference data when reporting Jumping Mechanography measurement results. (rainer rawer, harald schubert)
14:30 session 6 tenDon anD cartIlage (chair: Marco toigo)
14:30 nn
15:00 regenerative medicine – repair of cartilage (Brendon noble)
15:30 Free communications - abstracts 31, 06 & 33
16:15 Coffee break
16:45 JMnI Board meeting
17:45 IsMnI Board Meeting
19:00 Speaker´s Dinner at Mariners (Neptune Quay Ipswich IP4 1AX)
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04th-07th May 20128th international workshop
for MUsCUloskeletal & neUronal interaCtions
Sunday, May 6th
09:00 session 7 phYsIcal anD pharMacologIcal InterVentIons (chair: Dieter Felsenberg)
09:00 the battle against age-related muscle and bone weakness (george lyritis)
09:25 osteocytes and mechanical stimulation (Val Mann)
09:50 Free communications - abstracts 38, 03, 27, 44, 10, 25, 08 & 21
11:10 Coffee break
11:30 session 8 peDIatrIcs (chair: eckhard schönau)
11:30 osteogenesis Imperfecta: new genes and therapies (oliver semler)
12:00 Functional ability of children with cerebral palsy - evaluation of an intensive rehabilitation concept (christina stark)
12:15 Implementation of the leonardo Mechanograph® for gait analysis in pediatrics (eckhard schönau)
12:30 adaptation of the muscle-bone unit in the lower leg of children and adolescents consequent to exercise (elmar anliker)
12:45 Muscle treatment in small children with vibration exercise (Dagmar siebold)
13:15 Lunch
14:00 session 9 orphan DIseases (chair: Frank rauch)
14:00 hypophosphatasia (Franz Jakob)
14:30 Free communications - abstracts 42, 37, 28, 11, 39, 09, 19, 18 & 01
16:00 Coffee break
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04th-07th May 2012University CaMpUs sUffolk ipswiCh, United kingdoM
16:15 session 10 nerVes, Muscles anD Bones (chair: Donato agnusdei)
16:15 nerve derived control of bone cell function (chantal chenu)
16:45 Integrins in skeletal muscles – What are they good for? (Isabelle piec)
17:15 Free communications - abstracts 40, 36, 17, 32, 13, 34, 30, 43 & 04
19:00 Party at Waterfront Bistro Ipswich (15 Regatta Quay Ipswich, Suffolk IP4 1FH, 20 GBP contribution towards expenses)
Monday, May 7th
09:00 session 11 MethoDs oF DIagnostIcs (chair: gabi armbrecht)
09:00 Bone structure, geometry, and strength (alan Boyde)
09:30 Free communications - abstracts 23, 22, 14, 12 & 41
10:20 Coffee break
10:40 session 12 clInIcal proBleMs oF osteologY (chair: oliver Bock)
10:40 sequence therapy - experience and benefit (Jean-pierre Devogelaer)
11:05 long-term safety in Drug treatment of osteoporosis – recent controversies - aFF, onJ (Manuel sosa)
11:25 Free communications - abstracts 24 & 35
11:45 end of the meeting and farewell
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04th-07th May 20128th international workshop
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Speakers
Donato agnusdei, [email protected]
elmar anliker, [email protected]
gabriele armbrecht, [email protected]
Daniel Belavy, [email protected]
oliver Bock, [email protected]
alan Boyde, [email protected]
chantal chenu, [email protected]
hans Degens, [email protected]
Jean-pierre Devogelaer, [email protected]
Yannis Dionyssiotis, [email protected]
erik Fink eriksen, [email protected]
Dieter Felsenberg, [email protected]
José Ferretti, [email protected]
Franz Jakob, [email protected]
george lyritis, [email protected]
Val Mann, [email protected]
Brendon noble, [email protected]
Barbara obermayer-pietsch, [email protected]
Isabelle piec, [email protected]
Frank rauch, [email protected]
rainer rawer, [email protected]
Jörn rittweger, [email protected]
Martin runge, [email protected]
hans schießl, [email protected]
eckhard schönau, [email protected]
harald schubert, [email protected]
oliver semler, [email protected]
Dagmar siebold, [email protected]
Manuel sosa, [email protected]
christina stark, [email protected]
Marco toigo, [email protected]
andy Wong, [email protected]
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04th-07th May 2012University CaMpUs sUffolk ipswiCh, United kingdoM
01 02
WC WC
Stand Company
01 Novotec Medical GmbH
02 Amgen GmbH
Floor plan/Exhibition
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04th-07th May 20128th international workshop
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Abstracts
01 Dontas, I.the eFFect oF oVarIectoMY on cholesterol anD the InFlaMMatorY- assocIateD Markers rankl anD tFn- α In the rat anIMal MoDel oF postMenopausal osteoporosIs
02 Ducos, M.graVItatIonal loaDIng alone Is InsuFFIcIent to MaIntaIn Bone strength
03 aeberli, D.aDaptIon oF Bone shaFt geoMetrY In patIents WIth rheuMatoID arthrItIs anD the InFluence oD BIsphosphonate use
04 Iwamoto, J.Whole BoDY VIBratIon exercIse IMproVes BoDY Balance anD WalkIng VelocItY In postMenopausal osteoporotIc WoMen treateD WIth alenDronate: galIleo anD alenDronate InterVentIon traIl (gaIt)
05 Jeffrey, M.age- relateD change anD ethnIc DIFFerences In neuroMuscular FunctIon
06 lancashire, h. t.eValutIon oF a harD- WIreD epIMYsIal electroDe construct For MultI- channel, hIgh BanDWIDth prosthetIc control
07 Boerst, h.Falls, phYsIcal actIVItIes anD VIt D 3 seruM concentratIon In WoMen WIth prIMarY anD seconDarY osteoporosIs: a prospectIVe stuDY – FIrst BaselIne results
08 Meiring, r. M.a stuDY exaMInIng the eFFect oF tWo- Year phYsIcal actIVItY hIstorY on current Bone health status anD BoDY coMposItIon usIng pQct In pre- puBertal south aFrIcan chIlDren
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04th-07th May 2012University CaMpUs sUffolk ipswiCh, United kingdoM
09 soucek, o.patIents WIth turner sYnDroMe anD IsolateD shox DeFIcIencY haVe sIMIlar Bone geoMetrY But DIFFerent traBecular Bone MIneral DensItY at the raDIus
10 osawa. Y.eFFekts oF 13- Week exercIse prograM WIth Whole- BoDY VIBratIons on Muscle hYpertrophY, Muscle strength, anD aBDoMInal Fat reDuctIon In untraIneD aDults
11 Veilleux, l.-n.aBnorMalItes In Muscle DensItY anD Muscle FunctIon In hYpophosphateMIc rIckets
12 Zikmund, t.3D IMagIng MethoDs In QuantIFYIng rat FeMoral Bone changes WIth preDnIsolone aDMInIstratIon: μct, seM anD conFocal lM
13 Veilleux, l.- n.JuMpIng MechanographY In patIents WIth osteogenesIs IMperFecta tYpe 1
14 ritter, Z.osteocYtes: MorphologIcal analYsIs oF Bone BIopsIe oF the JaW FroM healthY anD osteoporotIc WoMen usIng sYnchrotron raDIatIon coMputeD toMographY
15 Barbosa, a. p.Does suBclInIcal hIperthYroIDIsM aFFect Muscle Mass anD Bone MIneral DensItY In the postMenopause?
16 anliker, e.aDaptatIon oF the Muscle- Bone unIt In the loWer leg oF chIlDren anD aDolescents conseQuent to exercIse
17 Mascarenhas, M.Muscle Mass, Bone QualItY anD testosterone leVels In a group oF norMal Men
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04th-07th May 20128th international workshop
for MUsCUloskeletal & neUronal interaCtions
18 Ireland, a.upper lIMp Muscle -Bone asYMMetrIes In elIte JunIor tennIs plaYers
19 grygorierva, n.FunctIonal actIVItY anD QualItY oF lIFe In patIents WIth VerteBral Fractures
20 povorzynyuk, V.VerteBral paIn sYnDoMe In elDerlY patIent
21 povorzynyuk, V. eFFect oF strontIuM ranelate oF VerteBral paIn sYnDroMe anD FunctIonal aBIlItIes In postMenopausal WoMen WIth sYsteMIc osteoporosIs
22 povorzynyuk, V.traBecular Bone score In norMal urkaInIan WoMen oF DIFerent age
23 povorzynyuk, V.QuantItatIVe ultrasounD DenDItoMetrY anD Felax In eValutIon oF structural - FunctIonal state oF Bone In postMenopausal WoMen
24 povorzynyuk, V.VItaMIn D DeFIcIencY anD Bone MIneral DensItY
25 Beccard, r.the eFFect oF Whole-BoDY VIBratIon anD IgF-I on clostrIDIuM BotulInuM toxIn tYp a InDuceD Bone DegraDatIon
26 Miokovic, t.calF Musculature trophY DurIng 60-DaYs BeD rest anD the eFFect oF tWo DIFFerent counterMeasure exercIses
27 Devereux, g.traDItIonal Versus non-traDItIonal Measures oF IsoMetrIc exercIses IntensItY: relatIVe IMportance For suBseQuent carDIoVascular aDaptIon
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04th-07th May 2012University CaMpUs sUffolk ipswiCh, United kingdoM
28 stathopoulos, k.the eFFect oF IDIopathIc hYpercalcIurIa on Bone MIneral Mass anD Bone geoMetrY In post-Menopausal WoMen: a tIBIa pQct stuDY
29 rittwerger, J.counterMeasures oF Muscle WastIng: Does Bone reap soMe BeneFIts?
30 rittweger, J.Muscle x-raY attenuatIon DurIng 90 DaYs oF BeD rest WIth -6 heaD DoWn tIlt
31 lopez, s.What Do BIsphosphonate-assocIateD osteonecrosIs oF the JaW anD “phossY JaW” haVe In coMMon?
32 Yang, p.the role oF Muscle contractIon In huMan tIBIa DeForMatIons DurIng DIFFerent locoMotIVe actIVItIes: an In VIVo stuDY
33 cornish, J.In VItro eValuatIon oF coMMercIallY aVaIlaBle scaFFolDs For use In Musculoskeletal regeneratIVe MeDIcIne
34 gast, u.short DuratIon resIstIVe exercIse sustaIns neuroMuscular FunctIon aFter BeD rest
35 Bock, o.eFFects oF loW Dose calcIuM anD VIt D suplMentatIon on Bone DensItY anD structure Measure In-VIVo BY µct at the DIstal tIBIa In postMenopausal WoMen WIth lose Bone Mass
36 Bock, o.atYpIcal suBtrochanterIc anD DIaphYseal FeMoral Fratures assocIateD WIth long-terM BIsphosphonate use In postMenopausal osteoporosIs - a case stuDY
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04th-07th May 20128th international workshop
for MUsCUloskeletal & neUronal interaCtions
37 gallagher, J. a.the earlY onset anD seVere osteoarthropathY oF alkaptonurIa has MaJpr lessons For the pathogenesIs oF osteoarthrItIs
38 Beller, g.eFFects oF strontIuM ranelate coMpareD to alenDronate on strength paraMeters at the tIBIa In post Menopausal osteoporotIc WoMen aFter a treatMent perIoD oF 2-Years
39 goemaere, s.transsexual WoMen haVe loW Bone Mass BeFore cross-sex horMonal treatMent anD gonaDectoMY
40 Vandewalle, s.Male oBese aDolescents haVe stronger anD BIgger Bones than theIr norMal-WeIghteD peers.
41 Dionyssiotis, Y.correlatIon oF Bone area WIth Muscle area In loWer lIMBs In spInal corD InJurY Vs. aBle BoDIeD suBJects
42 Masieri, F.pulseD electroMagnetIc FIelDs In BoVIne JoInt cartIlage
43 Bazarra-Fernandez, a.Wrong eVIDence-BaseD MeDIcIne, osteoporosIs anD targeteD Breast cancer therapIes
44 stege, u.eValuatIon oF phYsIcal actIVItY anD VItaMIn D seruM leVels In WoMen WIth prIMarY anD seconDarY osteoporosIs: a prospectIVe stuDY – FIrst BaselIne results
we would like to thank our sponsors for their valued support of our symposium!