05 the new game changing lc triple quad from bruker bradley duruttya - bruker daltonics
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5 minutes of fameTRANSCRIPT
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Introducing the EVOQ LC-Triple Quadrupole
The New Game Changing LC Triple Quad from
Bruker
Bradley Duruttya
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Introducing the EVOQ LC-TQ
EVOQ QubeTM
EVOQ Elite
• Bruker Triple Quadrupole MS• VIP Heated-ESI• Active Exhaust• IQ Dual Ion Funnel• PACER Software• Mass Range: 10-1250 amu
• Bruker Analytical LC• Advance HPLC (8000 psi)• Advance UHPLC (15000 psi)• Advance UHPLC with OLE (15000 psi)
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One Mission
EVOQ was designed for a singular purpose – to reliably quantify thousands of real samples in the fastest ‘sample-to-report’ time possible.
Food Testing
Environmental Testing
Toxicology
Discovery PK
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Keys to Achieving Mission
Sustained High-Sensitivity• Orifice interface, Active Exhaust, IQ Dual Ion Funnel and VIP-HESI
Increased Capacity through Higher Robustness• High-sensitivity, Flat-tuning IQ Dual Ion Funnel
Fastest ‘Sample-to-Report’ time• Pacer software with Exception Based Data Review
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Active Exhaust vs Equine Plasma – NO DIVERT VALVE USED
• 500 equine plasma samples analyzed with four calibration curves, two bracketing, two spread between samples.
• No divergence between calibration curves run before and after samples were run.
Picture of ion source after running 500 equine plasma samples and 4 calibration
curves.
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A Picture is Worth a Thousand Words
Picture of the EVOQ LC-TQ ion source after running 500 equine plasma samples and 4 calibration
curves.
Game-Changing Performance
Stays cleaner maintains Sensitivity
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Improved Dual Ion Funnel Design
Inter-laced Quadrupole Dual Ion Funnel• Linear, on-axis design of the IQ dual ion funnel virtually eliminates
instrument-to-instrument tune variability.• IQ dual ion funnel does not require DC; no impact on tuning
parameters after running hundreds of matrix rich samples.• Less tuning, Less cleaning, Less maintenance equals more
robustness and more samples
User benefit provided by Bruker• Effortlessly transfer methods between EVOQ instruments.• Save time by eliminating re-tuning.
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Sustained Sensitivity: 5-1000fg Alprazolam in Rat Plasma On Column
5-50fg curve (n=3)
Full Calibration Range
Resp.Factor
EVOQ Elite with Advance HPLC500uL/min LC flow rate 5-90% Acetonitrile (0.1% Formic) in 1.8min C-18, 3u, 2.1x50, ACE column2uL injected
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PACER Software allows Faster Review
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See more on our Microsite
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Game Changing Performance for the Business of Quantitation
Copyright 2012 Bruker Corporation. All Rights Reserved.
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Questions
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