1 organic polymers synthetic and natural chapter 22 copyright © the mcgraw-hill companies, inc....
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Organic Polymers Synthetic and
NaturalChapter 22
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
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A polymer is a high molar mass molecular compound made up of many repeating chemical units.
Naturally occurring polymers
•Proteins
•Nucleic acids
•Cellulose
•Rubber
Synthetic polymers
•Nylon
•Dacron
•LuciteSilverstone®: polytetrafluoroethylene
Tyvek
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The simple repeating unit of a polymer is the monomer.
Homopolymer is a polymer made up of only one type of monomer
( CF2 CF2 )n
Teflon
( CH2 CH2 )n
Polyethylene
( CH2 CH )n
Cl
PVC
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Copolymer is a polymer made up of two or more monomers
Styrene-butadiene rubber
( CH CH2 CH2 CH CH CH2 )n
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R groups on same side of chain
Isotactic
R groups alternate from side to side
Syndiotactic
R groups disposed at random
Atactic
Stereoisomers of Polymers
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Polymerization: Addition reactions
• Involve unsaturated compounds containing double or triple bonds• Particularly C=C and C≡C• Examples:
− Hydrogenation− Reactions of hydrogen halides and halogens with alkenes and alkynes− Polymerization
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Mechanism of addition polymerization
initiator
repeating unit (monomer)
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Vulcanization: Properties of rubber
before vulcantization after vulcantization
relaxation after stretching
stretched
sulfur cross-links
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Polymerization: Condensation reactions
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• Termed polypeptides • Play a key role in nearly all biological processes
− Enzymes, the catalysts of biochemical reactions − Transport of materials− Storage of vital substances− Coordinated motion− Mechanical support− Protection against diseases.
ProteinsProteins are polymers of amino acids
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Amino acids are the basic structural units of proteins.
• Contain at least one amino group (-NH2)
• And at least one carboxyl group (-COOH)
• Existing form is pH dependent
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Amino acids are joined in a protein by the formation of a peptide bond
+H3N C C N C C O- + H2O
H
R1
H
R2
O O
H
+H3N C C O- + +H3N C C O-
H
R1
H
R2
O O
Peptide (amide) bond
Dipeptide – contains two amino acid residues
planar
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20 amino acids can form 202 or 400 dipeptides.
Protein with 50 amino acid residues can be arranged in 2050 or 1065 ways.
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Polypeptide chain: repeating amide bonds
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Carbon
Nitrogen
Oxygen
R group
Hydrogen
The structure is held in position by intramolecular hydrogen bonds (………)
Protein Structure: -helix
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Hydrogen bonds in parallel and antiparallel -pleated sheets
Protein Structure: -Pleated Sheets
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primarystructure
Protein Structure
secondarystructure
tertiarystructure
quaternarystructure
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Protein Structure
Intermolecular Forces in a Protein Molecule
ionic forces
ionic forces
hydrogenbonds dispersion
forces
dispersionforces
dispersionforces
dipole-dipoleforces
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Protein Structure
The structural changes that occur when oxygen binds to the heme group in hemoglobin.
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Denatured proteins: no longer exhibit normal biological activities.
Denaturation can be caused by pH, denaturants (special reagents) or temperature
Can be reversible or irreversible
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Nucleic Acids
Nucleic acids are high molar mass polymers that play an essential role in protein synthesis.
1. Deoxyribonucleic acid (DNA)
2. Ribonucleic acid (RNA)
DNA molecule has 2 helical strands. Each strand is made up of nucleotides.
Electronmicrograph of DNA
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The Components of the Nucleic Acids DNA and RNA
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Base-Pair Formation by Adenine and Thymine and by Cytosine and Guanine