1 tips on how to present research findings (dichotomous data) january 2010
DESCRIPTION
3 Shingles Prevention Study – Results Outcome Event rate PlaceboZostavax Herpes zoster overall 3.3%1.6% Herpes zoster age ≥ %2.2% PH neuralgia overall 0.42%0.14% PH neuralgia age ≥ %0.21% RRRARR 51%1.7% 37%1.3% 66%0.3% 67%0.4% Time (Yrs) NNT 95% CI 4 yrs – 72 4 yrs – yrs – yrs – 425 Reference text boxTRANSCRIPT
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Tips on how to present research findings (dichotomous data)
January 2010
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Shingles Prevention Study – Results
OutcomeEvent rate
Placebo Zostavax
Herpes zoster overall 3.3% 1.6%
Herpes zoster age ≥ 70 3.5% 2.2%
RRR ARR
51% 1.7%
37% 1.3%
Time(Yrs)
NNT95% CI
4 yrs 5950 – 72
4 yrs 7756 – 124
Reference text box
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Shingles Prevention Study – Results
OutcomeEvent rate
Placebo Zostavax
Herpes zoster overall 3.3% 1.6%
Herpes zoster age ≥ 70 3.5% 2.2%
PH neuralgia overall 0.42% 0.14%
PH neuralgia age ≥ 70 0.64% 0.21%
RRR ARR
51% 1.7%
37% 1.3%
66% 0.3%
67% 0.4%
Time(Yrs)
NNT95% CI
4 yrs 5950 – 72
4 yrs77
56 – 124
4 yrs 363263 – 587
4 yrs 234162 – 425
Reference text box
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ARBs – Reductions in HF Hospitalizations
OutcomeEvent rate
Placebo Drug
Hospitaliz’ns (candesartan) 24% 20%
Hospitaliz’ns(valsartan) 18% 14%
RRR ARR
18% 4%
24% 4%
Time(Yrs)
NNT95% CI
3.5 yrs 2316-41
2 yrs23
15-42
Reference text box
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Event rate 24% vs 20% - HospsRRR 18%ARR 4%NNT 23 (14 – 41) 3.5 yrs
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Questions or Further HelpDr Mike AllenDirector Evidence-based ProgramsDalhousie CME
For supportive tools visit: http://cme.medicine.dal.ca/EBM.htm