11 james k. murray, jr., phd, associate professor & chair, chemistry department, immaculata...
TRANSCRIPT
11
James K. Murray, Jr., PhD, Associate Professor & Chair, Chemistry Department, Immaculata
University
Barry F. Stein, PhD Senior Project Consultant
Mary J. Burch, PhD Project Consultant
33
Nano Overview Demonstrative Experiments
Lessons & lesson plans
Adaptation to your class
44
Opening
Salvo
•Profiles and backgrounds
•Objectives
•Quiz
Nanotechnolo
gy Beginn
ings
•Feynman Article
•Definitions, Opportunities and Applications
•Videos
Nano Gold
Experiment
•Tyndall Effect
•Hands-on Au Experiment
•Tele-experimentation thru NTEN portal
BREAK
Workshop Content
55
New Nano Materi
als
•Quantum Dots & Hard Drive Heads
•Carbon Nanotubes
•Disease Diagnosis & Treatment
Experiment: Nanomaterial Effects
•Physical: Particle Size Effects
•Chemical: Surface Area Effects
Nanoproducts and Wrap
Up
•Today’s Products
•Risk & Risk Perception
•Post Quiz and Future Work
LUNCH
Workshop Content Continued
66
The ability to manipulate and control materials at the level of atoms and molecules to design new functionality. The nanoscale: 1nm=10-9m
An enabling science that – applies to all disciplines – blurs the distinction between biology, chemistry, & physics
• Nanotechnology will be pervasive in the upcoming decades New career opportunities for students
What is Nanotechnology?
7
Nano Size
Cell Size & Scale
http://learn.genetics.utah.edu/content/begin/cells/scale/
88
Generally nanotechnology deals with structures 100 nanometers or smaller, and involves developing materials or devices within that size.
99
The Economic Driver of the 21st Century“Nanotechnology’s impact on health, wealth and security of the world’s people is expected to be at least as great as the combined influences in this century of antibiotics, the integrated circuit and human-made polymers.”
Federal Interagency Working Group Report on Nanotechnology
1010
What's 100,000 times thinner than a strand of hair? A nanometer. Discover the nanotech boom in Berkeley, where researchers are working to unlock the potential of nanoscience to battle global warming and disease.
http://www.youtube.com/watch?v=S4CjZ-OkGDs
1111
Magnification vs. Year
Scanning Probe Microscopy (1980’s+)
0.0001 µm (0.1 nm) Atoms and molecules
Electron Microscope (1930’s+)0.01 µm IC’s and Material
Science
Optical Microscope (1660-1800)
2µm Water microorganisms
1600 1700 1800 1900 2000
1000
1
1000000
1212
Atomic Force Microscope
Carbon nanotube
1313
► As of August 2009, there were more than 1015 manufacturer-identified nanotech products1
1The Woodrow Wilson International Center for Scholars
1414
1515
Materials-nanotubes Life Sciences-drug development & delivery,
innovative therapies, diagnostics Sensors-physical, chemical, biological Ultra-high speed computing, Molecular
Electronics Nanomachines Green technology: Fuel cells, solar cells, new
light sources, microbial cleanup, filtration
16
Clean Water Challenge Now!
Nanofiltration Nano for Remediation
Nanostructured ◦ Arrays of capillaries◦ Carbon nanotubes
Nanoreactive Membranes◦ Functionalized nanoparticles ◦ Dendritic polymers
Single enzyme nanoparticles
Zeolites Nanoscale
semiconductor photocatalysts
Carbon nanotubes
17
Need to do a more general slide on risk, risk perception
18
Nano-Sized: Risk and Risk Perception
Carbon nanotubes: Scarring in mouse lungCarbon nanoparticles: no effect
C&E News, Oct 27, 2009
"A key question to be answered is whether or not a particular nanoparticle has toxic or hazardous properties that are truly different from identical particles in their bulk form.“ Mark Wiesner, Duke University, Center for the Environmental Implications of NanoTechnology
Nanotech Protection: Current Safety Equipment May Not Be Adequate (Oct. 16, 2009) — Canadian engineers suggest that research is needed into the risks associated with the growing field of nanotechnology manufacture so that appropriate protective equipment can be developed
19
Hot Nanotechnology Career Areas
Medicine: diagnostics and therapeutics (e.g.,
drug delivery)
Computers: the next generation
Energy: capture, storage, & use;
fuel cells, batteries
Environmental remediation: in conjunction with
genetically-modified (GM) microbes
Robotics: many uses
Manufacturing: self-assembly; “bottom-up” fabrication of novel materials
Commerce: Radio Frequency
Identification (RFID) “smart” tags
Space exploration:
space elevator
NSF: By 2015 we need 2 million nanotech-savvy
workers
20
Colloidal Gold Experiment
Objective◦ Gain an understanding that nano size leads to changes
in optical properties of materials Process
◦ Conduct Experiment◦ Discuss & identify
How it relates to topics that you teach Where this material can be inserted into your
classroom
2121
Mesogold
Mesosilver
“The Blue Man” as seen on Today Show
How do I know there are gold particles there?Why is the color pinkish-purple?
2222
2323
400-450 nm
450-480 nm 450-560 nm
560-600 nm
600-630 nm640-700 nm
Color WheelShows Complementary Colors
2424
Nanospectra Biosciences,
Inc.
25
Cancer Treatment ApplicationA Rifle Shot
Cisplatin is a drug that treats cancer successfully. Unfortunately, the drug can harm healthy cells as well as cancerous ones.
Nano gold particles combined with DNA deliver drugs directly to where they are needed inside a patient’s body.
Once inside the cancer cells, cisplatin is then released, selectively killing the cancer cells.
26
Nano Size Experiments
Objectives◦ Demonstrate that nano size leads to changes in the way
that a material interacts both physically and chemically◦ Gain an understanding of surface area and size and how
they play a role in physical and chemical reactions Process
◦ Conduct Experiments◦ Discuss & identify
How they relate to topics that you teach Where this material can be inserted into your classroom
2727
Your Task
Deliver two nanotechnology lessons to two classes
2828
Nanotechnology for Middle/High School Teachers
A three-credit graduate course that serves as an introduction to nanotechnology, a field that is redefining the scientific landscape and will shape the future scientific careers of students
◦ One third of the course is on-line nanotechnology content◦ Two-thirds is focused on the experiments and development
of lesson plans that the individual teacher will deliver to students in the fall following the course