13th annual nih graduate student research …...the symposium poster session, and we acknowledge the...

13th ANNUAL

NIH GRADUATE STUDENT RESEARCH SYMPOSIUM THE FACES OF TOMORROW'S SCIENCE

FEBRUARY 23, 2017 NIH NATCHER CONFERENCE CENTER, BETHESDA, MARYLAND

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13th ANNUAL

NIH GRADUATE STUDENT RESEARCH SYMPOSIUM THE FACES OF TOMORROW'S SCIENCE

2017

FOREWORD AND ACKNOWLEDGEMENTS .................. 2

PROGRAM OF EVENTS ................................................ 4

NIH GRADUATE PARTNERSHIPS PROGRAM GRADUATION AWARD RECIPIENTS ............................ 5

KEYNOTE SPEAKER .................................................... 8

STUDENT SPEAKERS.................................................. 9

OUTSTANDING MENTOR AWARD RECIPIENTS ..........11

STUDENTS..................................................................12

POSTERS ....................................................................17

Graduate Partnerships Program Office of Intramural Training & Education Office of Intramural Research National Institutes of Health U.S. Department of Health & Human Services

FOREWORD

Every year, the National Institutes of Health (NIH) Graduate Student Research Symposium showcases the breadth of scientific research and the achievements of the graduate student community at the NIH. The symposium is the largest graduate student event of the year, an event in which graduate students can come

together to share their research, appreciate the work of their colleagues, and celebrate the successes of the

graduate student community.

In its thirteenth year, this annual symposium provides an opportunity to acknowledge the scientific

accomplishments of the hundreds of graduate students working on their dissertation research at the NIH. This

symposium highlights the spectrum of scientific research conducted by graduate students at the NIH, who

represent numerous universities across the world and span nearly all institutes and centers within the NIH. The

NIH Graduate Research Symposium recognizes the diversity of research specialties supported by the NIH and

exhibits the scientists of tomorrow, from those developing new research proposals to those preparing to defend

years of dissertation research.

This symposium will provide the graduate student community with the chance to hear about the scientific work

of our peers in several formats. In the morning, we will be holding our inaugural elevator pitch competition in

which current graduate students will be judged on their ability to explain their science to a general audience in

two minutes or less. Dr. Sharon Milgram, Director of the Office of Intramural Training and Education (OITE), will

deliver welcoming remarks, followed by four current students, who will present scientific talks chosen based

on scientific merit and diversity. In the afternoon, students will present their research through scientific posters

judged by NIH postdoctoral fellows and staff scientists. Winners of the poster competition will be awarded the

prestigious NIH Graduate Student Research Award generously funded by the OITE.

Following the poster session, we are honored to welcome our keynote speaker, Dr. Rajendrani Mukhopadhyay,

managing editor at American Society for Biochemistry and Molecular Biology (ASBMB) Today. Dr. Mukhopadhyay

pursued a PhD in biophysics and biochemistry in the laboratory of Dr. Jan Hoh at Johns Hopkins University. After

struggling with the lack of instant gratification in science, Dr. Mukhopadhyay realized she loved the challenge of

graduate school and the success of finishing. She pursued a former passion of hers after graduating and started

her science-writing career at the American Chemical Society. Dr. Mukhopadhyay then joined ASBMB, writing

feature stories and scientist profiles for ASBMB Today and the Wild Types blog and later becoming senior editor

of ASBMB Today. She used knowledge gained from her PhD training to develop a strong sense of curiosity, the

ability to ask the right questions, and the ability to frame all the information into a story—qualities necessary for

a writing career and that will help us as graduate students develop a scientific project. Today, Dr. Mukhopadhyay

will present how storytelling can make you a better scientist. Her story and advice will be valuable for NIH

graduate students in addressing how graduate school can be an opportunity for personal growth and how

graduate students can find their dream career path.

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NIH GRADUATE STUDENT RESEARCH SYMPOSIUM 2017

Following our keynote address, we will present the awards for outstanding research mentors. Our success as

graduate students would not be the same without the guidance of high-quality research mentors, who support us

in innumerable ways, from providing networking opportunities to career development advice. We are grateful for

the influential mentorship provided at the NIH to help us become independent scientists and forge relationships

extending beyond graduate school. Three outstanding mentors nominated by their students will be honored for

their leadership, support, and dedication to their graduate students. Afterwards, we will conclude the day with a

graduation ceremony to recognize those students who have defended their dissertations within the past year. Dr.

Sharon Milgram will present the recent graduates with a certificate in honor of their accomplishments.

We are thankful for the opportunity to share our research with the entire NIH community at the 13th Annual NIH

Graduate Student Research Symposium. We thank all of the graduate students who participated in this event and

those who have provided us with continuous support in our scientific careers. We hope this event establishes new

connections and collaborations, and inspires future scientific contributions to the community at the NIH.

ACKNOWLEDGEMENTS

We are grateful to the Training and Scientific Directors of the NIH Institutes and Centers, the Graduate

Partnerships Program (GPP) Directors, and the Graduate Student Council (GSC) for their continuous support

of the graduate student community and for the opportunity to recognize the achievements of the NIH graduate

students at this symposium. We would like to thank Dr. Gail Seabold and Dr. Courtney Kurtyka for organizing

the symposium poster session, and we acknowledge the effort of the postdoctoral fellow and staff scientist

judges for helping to make the poster competition possible. We would like to thank the 2016 GSC co-chairs,

Kara Fulton and Kimberly Breglio, for managing the Outstanding Mentor Awards and for all of their efforts

and dedication to the GSC and graduate student community. This symposium would not be possible without

the help of the Office of Intramural Training and Education (OITE). We are especially thankful for Dr. Sharon

Milgram, Dr. Philip Wang, Dr. Phil Ryan and other OITE staff who have contributed significantly to the planning

of this event. We would like to extend a big thank you to Dr. Rajendrani Mukhopadhyay for her enthusiasm and

willingness to deliver our keynote address. Finally, we would like to thank the graduate students, mentors,

alumni, and all attendees whose participation made this event successful.

THE 13TH ANNUAL NIH GRADUATE RESEARCH SYMPOSIUM COMMITTEE

Kimberly Breglio, NIAID/University of Oxford

Leda Lotspeich-Cole, NICHD/Johns Hopkins University

Carly Starke, NIAID/Georgetown University

Keyla Tumas, NIAID/Georgetown University

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PROGRAM OF EVENTS

9:00 am-10:00 am ELEVATOR PITCH COMPETITION

Lower Lobby

10:00 am-10:15 am WELCOME

Room E1/E2 Sharon L. Milgram, PhD

Director, NIH Office of Intramural Training & Education (OITE)

10:15 am-11:45 am

Room E1/E2

STUDENT ORAL PRESENTATIONS

Lydia Louis, Rutgers, The State University of New Jersey, NCI-DCEG

Personal Use of Organochlorine Insecticides and Cancer Risks Among the Agricultural Health Study Farm Spouses

Nityashree Shivaprasad, Georgetown University, NCI

FGFR4 specific Chimeric Antigen Receptor (CAR) T Cell Therapy Against Rhabdomyosarcoma

Rodrigo Matus Nicodemos, Johns Hopkins Univeristy, NIAID

HLA-A and HLA-B Down Modulation in HIV-Infected Cells Occurs Late in the Viral Replicative Cycle

Christie Campla, University of Oxford, NEI

Frmpd1: A Novel Gene Involved in Rod Photoreceptor Maturation

11:45 am-12:45 pm POSTER SESSION I

Atrium Odd numbered posters presenting

12:45 pm-1:45 pm POSTER SESSION II

Atrium Even numbered posters presenting

2:00 pm-3:00 pm KEYNOTE ADDRESS

Ruth L. Kirschstein Rajendrani Mukhopadhyay, PhD Auditorium Managing Editor, ASBMB Today

3:00 pm-4:00 pm

Ruth L. Kirschstein Auditorium

AWARDS CEREMONY

Graduation Ceremony

Certificates presented by: Sharon L. Milgram, PhD, Director, NIH Office of Intramural Training & Education

Outstanding Mentor Awards

Daniel Reich MD, PhD John Kehrl, MD Jeffrey C. Smith, PhD

NIH Graduate Student Research Awards (NGSRAs)

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GPP GRADUATION AWARD RECIPIENTS

GPP GRADUATION AWARD RECIPIENT, DISSERTATION TITLE

NIH IC, MENTOR

UNIVERSITY, UNIVERSITY MENTOR

Fereshteh Aalamifar CC Johns Hopkins University Co-robotic Ultrasound Tomography: A New Paradigm for Dr. Bradford Wood Dr. Emad M. Boctor Quantitative Ultrasound Imaging Dr. Peter Pinto Dr. Arman Rahmim

Defne Bayik NCI Ihsan Dogramaci Bilkent Regulation of Human Monocyte Differentiation into M1- and Dr. Dennis M. Klinman University M2-like Macrophages

Shaunna Beedie NCI University of Aberdeen An Investigation of Thalidomide Derivatives for Clinical Use Dr. William Douglas Figg Dr. Neil Vargesson

Pascale Beliveau NHLBI Ecole Polytechnique Texture Analysis of Late Gadolinium Enhanced Cardiac Dr. Li-Yueh Hsu of Montreal Magnetic Resonance Images for Characterizing Myocardial Dr. Andrew E. Arai Dr. Farida Cheriet Fibrosis and Infarction

Murat Bilgel NIA Johns Hopkins University A Multivariate Nonlinear Mixed Effects Model for Studying Dr. Susan M. Resnick Dr. Jerry L. Prince Preclinical Alzheimer’s Disease Markers of Neuropathology, Neurodegeneration, and Cognition

Allyson Lindsay Byrd NHGRI Boston University Bacterial Strain-Tracking across the Human Skin Landscape Dr. Julie Segre Dr. W. Evan Johnson in Health and Disease Dr. Yasmine Belkaid

Xiu-Tang Cheng NINDS Shanghai Jiao Tong Mechanisms Driving Axonal Transport of Autophagosomes Dr. Zu-Hang Sheng University and Defective Mitochondria

Clara Di Germanio NIA Universitá degli Studi Conditioned Medium Derived from Rat Amniotic Epithelial Dr. Rafael de Cabo di Teramo Cells Confers Protection Against Inflammation, Cancer and Dr. Barbara Barboni Senescence

Caitlin Moira Fox NICHD Johns Hopkins University The Role of Heparan Sulfate Proteoglycans During Dr. Ajay Chitnis Development of the Zebrafish Lateral Line

Armen A. Ghazarian NCI The George Washington The Testicular Dysgenesis Syndrome: Associated Maternal Dr. Katherine McGlynn University Exposures and Future Burden of Testicular Germ Cell Tumors in the U.S.

Lucas Ray Church Glover NIMH University of Oxford Examining the Contribution of Dentate Gyrus Granule Cells Dr. Heather A Cameron Professor David M and Ambiguity Toward the Stress Response and Behaviour of Bannerman the Rodent

Eleonora Guadagnin NINDS University of Padova Pathogenic Mechanisms of Collagen Type VI-Related Dr. Carsten G. Bonnemann Muscular Dystrophies

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GPP GRADUATION AWARD RECIPIENTS


NIH IC, MENTOR


Kelly Andrew Hamilton Basic Helix Loop Helix Enhancer 40 in Neuronal Excitability and Synaptic Plasticity

NIA Dr. Mark Mattson

George Mason University Dr. Robert Lipsky

Yong He NIAAA Anhui Medical University Hepatic Mitochondrial DNA-TLR9-MicroRNA-223 Forms a Dr. Bin Gao Dr. Jun Li Negative Feedback Loop to Control Acetaminophen-Induced Acute Liver Injury and Inflammation

Jan Hoinka NLM Albert-Ludwigs-Aptamers in the Age of Big Data – Development and Dr. Teresa M. Przytycka Universität Freiburg Application of Algorithmic Solutions in the Field of High- Dr. Rolf Backofen Throughput Systematic Evolution of Ligands by Exponental Enrichment

Jessica Blythe Hostetler NIAID University of Cambridge Identification of Novel Plasmodium vivax Blood-stage Vaccine Dr. Rick Fairhurst Dr. Julian Rayner Targets

Carly Jean Houghton NHLBI Johns Hopkins University Characterization of Aerobic Respiration in the Free-Living Dr. Robert BalabanBacterium Paracoccus denitrificans

Ayesha Imtiaz NIDCD University of the Punjab Identification of Genes Involved in Severe Degree Hearing Loss Dr. Thomas B. Friedman Dr. Sadaf Naz

Andrew Scott Ishizuka NIAID University of Oxford Pre-Clinical and Clinical Evaluation of the Malaria Vaccines Dr. Robert A. Seder Dr. Simon Draper RH5-VLP and PfSPZ Vaccine Dr. Adrian Hill

Tao Jiang NIDCD University of Maryland, Conserved Role of Emx2 in Establishing Polarity of Sensory Dr. Doris Wu College Park Hair Cells Dr. Catherine Carr

Debra L. Johnson NHLBI University of Arizona Engagement of T Cells with Antigen Presenting Cells is Dr. Julie Donaldson Dr. Jean Wilson Dependent on Clathrin- Independent Endocytic Trafficking: The Role of Arf6 and Rab22

Senta Kapnick NHGRI Johns Hopkins University Understanding Cytotoxic T lymphocyte Function Using Models Dr. Pamela Schwartzberg of Primary Immunodeficiencies

Nathan N. Lee NCI Johns Hopkins University Role of RNA Processing Machinery and Signaling Pathways Dr. Shiv Grewal in Regulating the Dynamic Epigenetic Landscape through Heterochromatin Assembly

Valeria Martinez-Kaigi NIMH University of North Texas Validating the National Institutes of Health-Brief Fatigue Dr. Carlos Zarate Dr. Charles Guarnaccia Inventory and Characterizing Fatigue Symptoms Across Dr. Rodrigo Machado-Patient Populations Vieira

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NIH IC, MENTOR


Rafael Maso Prévide Acute and Long Term Effects of Triiodothyronine on the Hypothalamic-Pituitary-Adrenal Axys and its Physiological Importance

NICHD Dr. Stanko Stojilkovic

University of São Paulo Dr. Maria Tereza Nunes

Shashankkumar Jitendra Patel NCI Georgetown University

A Genome-Scale CRISPR Screen to Identify Essential Genes Dr. Nicholas P. Restifo Dr. Louis Weiner

for Cancer Immunotherapy

Karen Plevock Haase NHLBI University of North Regulation and Function of Centrosome Associated Proteins Dr. Nasser Rusan Carolina at Chapel Hill

Dr. Kevin Slep

Sara E. Reynolds NIAID University of Maryland, Characterization of the Cowpox and Mousepox Homologs Dr. Bernard Moss College Park of the Smallpox Virus B22 Protein and their Roles in Mouse Disease Models

Davide Risso NIDCD University of Bologna Genetic Epidemiology of Taste Perception and Cigarette Use Dr. Dennis Drayna Professor Donata Luiselli

Adam Rolt NIDDK University of Liverpool Development of Inhibitors of Hepatitis C Virus Dr. T. Jake Liang Dr. Andrew V. Stachulski

Marta Sanchez NIDA Universitat de Barcelona Noncanonical Neurotransmitter Activation of Catecholamine Dr. Sergi Ferré Dr. Vicent Casadó Receptors

Jenna Marlee Shapiro NICHD University of Cambridge Hydrogel Substrate Effects on Protein Kinase A and Dr. Constantine Stratakis Dr. Michelle Oyen Osteogenesis

Emily Simons Wires NIDA University of Maryland, The Effects of Dietary Intake on Endoplasmic Reticulum Dr. Brandon Harvey Baltimore Calcium Homeostasis

Dezmond Taylor-Douglas NICHD Howard University The Role of MC3R in the Regulation of Lipogenic and Lipolytic Dr. Jack Yanovski Dr. Kebreten Manaye Processes in Mice

Sarah A. Watters NCI University College London Dynamics of HIV-1 Viral Populations in Individuals Undergoing Dr. Frank Maldarelli Chemotherapy

Yinmeng Yang NCI Georgetown University TCR Activation Impact on Chimeric Antigen Receptor Therapy Dr. Terry Fry Against Acute Lymphoblastic Leukemia

Shile Zhang NCI Boston University Integrative Analysis of the Metastatic Neuroblasotoma Dr. Javed Khan Transcriptome

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KEYNOTE SPEAKER

RAJENDRANI (RAJ) MUKHOPADHYAY, PhD, is the managing editor of ASBMB

Today, the magazine published by the American Society for Biochemistry and

Molecular Biology. In 2004, right after she completed her PhD in biophysics

and biochemistry from Johns Hopkins University, Raj launched her science

writing career. She started off at the magazine section of the journal

Analytical Chemistry at the American Chemical Society (ACS). She reported

on many scientific advances and issues, including analyzing art, detecting

performance-enhancing substances in athletes and figuring out if dinosaur

proteins could be detected by mass spectrometry after being buried for 68

million years.

After working at the ACS for five years, Raj embarked on a freelance

career as a science writer and technical editor. She contributed articles

to a variety of outlets, including Chemical & Engineering News, Chemistry

World, and Epigenie.com. She also blogged regularly for the Polymer

Solutions Newsblog and edited grants, journal articles and technical

reports for scientists.

In 2011, Raj joined ASBMB. She wrote feature stories and scientist profiles

for ASBMB Today and the Wild Types blog. Stories she wrote for the magazine

included the controversy over the molecular effects of vitamin D, visa and

immigration issues for foreign scientists and a rare brain tumor that kills

children. Her story on the pediatric tumor won an EXCEL Award for feature

writing in 2016.

These days, Raj runs ASBMB Today’s operations. She is responsible for

getting an awesome magazine out the door every month! Her priorities

include editing every single story in the magazine so that each story is the

finest story it can possibly be, collaborating with the graphic designer on

the magazine’s layout, keeping track of deadlines and finding fresh voices

and perspectives to capture the current issues and interests in biomedical

research. Occasionally, she will go back to her roots and write a piece for

the magazine.

Her advice for people looking to become science writers is to read voraciously

and widely (from classic works of fiction to Buzzfeed), write at least 350

words daily, and always stay curious about the world.

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http:Epigenie.com


STUDENT SPEAKERS

LYDIA

NITYA

Lydia Louis

In 2014, Lydia Louis, MPH, joined the Occupational and Environmental Epidemiology

Branch (OEEB) of the Division of Cancer Epidemiology and Genetics (DCEG), at the

NCI as a predoctoral fellow. Following a BA in cellular biology/neuroscience and

French from Rutgers University Ms. Louis completed an MPH in environmental

and occupational health from the Rutgers University, School of Public Health

(formerly the University of Medicine and Dentistry of New Jersey). Her master’s

thesis focused on the effects of the herbicide 2,3,7,8-tetrachlorodibenzo-para

dioxin (TCDD) on human lung epithelial cells. She is currently a PhD candidate in

the Department of Environmental and Occupational Health at Rutgers University.

While in OEEB, Ms. Louis is working with investigators Melissa Friesen, PhD, and

Laura Beane Freeman, PhD, examining studies of pesticide exposure determinants

and cancer epidemiology among female spouses of the Agricultural Health Study,

the largest U.S. cohort study of pesticide exposures and health outcomes among

licensed pesticide applicators and their spouses. Ms. Louis is grateful for the

immense support of both her mentors and of DCEG.

Nityashree Shivaprasad

Nityashree Shivaprasad is a fourth year PhD candidate in the Georgetown–NIH

GPP. Nitya completed her undergraduate studies in 2009 from University of

Maryland, where she did a double major in Biochemistry (Honors) and Molecular

Genetics. During her undergraduate years, she was awarded a Howard Hughes

Medical Institute grant to pursue her research in the laboratory of Dr. George

Lorimer. Her research focused on understanding the structural biochemistry

of the chaperone protein GroEL. After graduation, she worked at Medimmune,

where she focused on developing antibody based therapeutics. During this

time, she also completed her master’s degree at Johns Hopkins University,

specializing in translational research and drug discovery. In 2013, she entered

the NIH-Georgetown partnership PhD program, and she is currently working in

the NCI Oncogenomics, under the mentorship of NCI Genetics Branch Deputy

Chief Dr. Javed Khan and Dr. Rimas Orentas of Lentigen Inc. Her thesis research

focuses mainly on developing immune-based therapies for the treatment of

pediatric tumors. Nitya is investigating cancer antigens that can be targeted by the

immune cells and developing pre-clinical therapeutics for treatment of pediatric

rhabdomyosarcoma. She is delighted to work with both her mentors, whose

effective collaboration has provided her with the opportunity to work in both an

academic and industrial environment on translational science research with the

potential to impact clinical treatment of pediatric cancers.

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STUDENT SPEAKERS

RODRIGO

CHRISTIE

Rodrigo Matus Nicodemos

Rodrigo is a third year PhD candidate in the NIH–Johns Hopkins University

Graduate Partnership Program. He received a BA in Genetics and MS in

Microbiology and Molecular Genetics from Rutgers University. At Rutgers he

studied the post-transcriptional regulation of CD40 ligand in CD4 T cells in the

laboratory of Dr. Lori Covey. He later joined the Human Immunology Section of

the Immunology Laboratory at the Vaccine Research Center (VRC) of the National

Institute of Allergy and Infectious Diseases (NIAID) as a Technical IRTA. Under the

mentorship of Drs. Richard Koup and Daniel Douek, Rodrigo worked to understand

the role of T cell receptor (TCR) recognition in the natural control of HIV-1 infection.

From this work he discovered new parameters that contribute to the control of

HIV-1 and has expanded that work to a PhD project with Drs. Koup and Douek to

determine the requirements for recognition and elimination of HIV-infected cells

by CD8 T cells. He is grateful for the opportunity to conduct HIV research that

can help combat this infectious disease, as well as for the wonderful learning

experiences he has obtained from the VRC and NIH community.

Christie Campla

Christie first began research in the lab of Dr. Meera Nanjundan at the University of

South Florida where she focused on the role of various TGFβ signaling mediators

and aberrantly spliced genes in autophagy and epithelial-mesenchymal transition

in ovarian cancer. As an undergraduate at USF, Christie also worked in the Protein

Engineering & Dynamic Living Systems Lab on genetically encodable elastin-like

peptides for treatment of chronic wounds as well as the Epithelial Carcinogenesis

Lab at CNIO in Madrid investigating the role of c-myc in the development of

pancreatic ductal adenocarcinoma. As part of the NIH-OxCam PhD program,

Christie works jointly in the Nuffield Laboratory of Ophthalmology with Drs.

Stephanie Halford and Sumathi Sekaran at Oxford as well as in the Neurobiology-

Neurodegeneration and Repair Laboratory with Dr. Anand Swaroop at the NEI.

Her current research is aimed towards understanding what controls appropriate

development and homeostasis of rod photoreceptors by carrying out a detailed

molecular and functional characterization of novel genes associated with these

processes, with the intent of improving cell therapies to create more functional and

viable cells for use in photoreceptor transplants.

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OUTSTANDING MENTOR AWARD RECIPIENTS

DR. REICH

DR. KEHRL

John Kehrl, MD

Dr. John Kehrl graduated from Michigan State University with a BS in Mechanical

Engineering, then attended medical school at Wayne State University followed by

an Internal Medicine residency at Yale University. He came to the NIH as a Clinical

Associate in the Laboratory of Clinical Investigation and then the Laboratory

of Immunoregulation. He became a Senior Investigator in the Laboratory of

Immunoregulation and then Chief of B-Cell Molecular Immunology Section. He

has a broad background in immunology and G-protein signaling having published

extensively in these fields. His laboratory research program aims to understand

how G-protein-coupled receptors (GPCR) transduce signals to downstream

effectors in immune cells, to discern the mechanisms that control these

responses, and to determine the physiologic consequences of G-protein activation

for lymphocyte function. Their studies make extensive use of gene modified

mice that have disruption of key genes in the chemokine receptor signaling

pathway and sophisticated imaging techniques including intravital two-photon

laser scanning microscopy (TP-LSM). As an extension of these studies, his lab is

also characterizing the functional roles of G-proteins, their regulators in a non-

canonical G-protein signaling pathway, which employs alternative activators and

effectors. Finally, they are investigating some aspects of the signaling pathway that

triggers autophagy and inflammasome activation in macrophages and other cell

types. In these studies they focus on the intersection between G-protein signaling

and inflammatory pathways.

Daniel Reich, MD, PhD

Dr. Daniel Reich is Senior Investigator at NIH/NINDS, where he directs the

Translational Neuroradiology Section and leads clinical studies focusing on

Multiple Sclerosis (MS). He studied math and physics at Yale and earned his MD

from Cornell and his PhD in neurophysiology from The Rockefeller University.

His training includes a fellowship in diagnostic neuroradiology and residencies in

radiology and neurology at Johns Hopkins. He is a founder of the North American

Imaging in MS cooperative and serves on the Advisory Committee of ACTRIMS and

the Scientific Advisory Board of the Race to Erase MS. He is an elected member

of the American Society of Clinical Investigation, the 2015 winner of the American

Neurological Association’s Derek Denny-Brown Young Neurological Scholar

Award, and the 2016 winner of the National MS Society’s Barancik Award for

Innovation in MS Research. Dr. Reich’s lab develops advanced MRI techniques to

understand MS and adapts those techniques for clinical trials and patient care. The

lab harnesses noninvasive imaging modalities to dissect biological mechanisms

of tissue damage, both by performing longitudinal studies on time scales relevant

for disease processes and by examining radiological-pathological correlations in

autopsy tissue and animal models.

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OUTSTANDING MENTOR AWARD RECIPIENTS

Jeffrey C. Smith, PhD

Dr. Jeffrey C. Smith received his BS degree in biological sciences from the

University of Maryland, College Park in 1973, and his PhD degree in physiology

from Johns Hopkins University in 1979. Subsequently, he held postdoctoral and

research associate positions in physiology at Harvard University and Northwestern

University. He was a Humboldt Fellow at the Physiological Institute, University

of Göttingen, Germany in 1990, and appointed in 1991 as Associate Professor in

the Department of Physiological Science at UCLA, where he was also a faculty

member in the Interdepartmental Program in Neuroscience. His research at

UCLA was supported in part by a NIH Research Career Development Award,

and he served as chairman of the departmental Graduate Affairs Committee. He

moved to the Basic Neuroscience Program at NINDS as a Senior Investigator in

1994 and was appointed Chief of the Cellular and Systems Neurobiology Section

(CSNS) in 1997. Research in the CSNS applies interdisciplinary experimental and

computational neuroscience approaches to investigate basic neurophysiological

mechanisms in the nervous system controlling breathing in mammals. He has

mentored 25 postdoctoral, graduate, and post-baccalaureate trainees, and over 25

undergraduate trainees including students who have received Goldwater, Fulbright,

Truman, or Rhodes Scholarships.

DR. SMITH


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Poster # Last Name, First IC University

27 Abaandou, Laura NIDDK George Mason University

94 Agbaegbu Iweka, Chinyere NHLBI Georgetown University

117 Aguiluz-Abunto, Maria Rosario NIA University of Pittsburgh Graduate School of Public Health

56 Alderson, Thomas NIDDK University of Oxford

69 Ansbro, Megan NIAID University of Cambridge

84 Arthofer, Elisa NICHD Karolinska Institute

85 Auslander, Noam NCI University of Maryland, College Park

93 Awasthi, Shivangi NCI University of Maryland, Baltimore

70 Baird, Michelle NHLBI University of Maryland, College Park

12 Breglio, Andrew NIDCD University of Oxford

20 Breglio, Kimberly NIAID University of Oxford

95 Brown, Markus NCI University of Maryland, College Park

64 Bullock, Jeanee NEI Georgetown University

86 Burke, Dennis NIAAA Brown University

38 Burnett, Joey NIDDK Brown University

5 Caffrey, Brian NCI University College Dublin

72 Campla, Christie NEI University of Oxford

58 Chen, Song NCI University of Maryland, College Park

102 Chiang, Wen-Yang NINDS Texas A&M University

31 Chopp, Laura NCI University of Pennsylvania

82 Clarke, Akanni NINDS The George Washington University

66 Collins, Joshua NIDCR Johns Hopkins University

18 Coonahan, Erin NIAID University of Oxford

6 Corps, Kara NINDS North Carolina State University

91 Cramer, Sarah NCI University of Maryland, College Park

109 Dashtestani, Hadis NICHD University of Maryland, Baltimore County

49 Davies, Sarah NHLBI Georgetown University

97 Dawson, Eric NCI-DCEG University of Cambridge

81 Deasy, Sarah NCI The George Washington University

62 Demmerle, Justin NICHD University of Oxford

1 Dennis, Allison NICHD Johns Hopkins University

108 Deuitch, Lora NIMH Karolinska Institutet

55 Dildine, Troy NCCIH Karolinska Institutet

41 Dold, Neil NCI University of Maryland, College Park

44 DuChez, Brian NIDCR Georgetown University

STUDENTS Listed alphabetically by name

14


110 Erben, Larissa NICHD University of Bonn

26 Fallon, Rebecca NIDA Johns Hopkins University

39 Fernandopulle, Michael NINDS University of Cambridge, Northwestern University Feinberg School of Medicine

98 Fulton, Kara NINDS Brown University

9 Garcia Grisales, David NCI University of Maryland, College Park

16 Gola, Anita NIAID University of Oxford

29 Gorrell, Laura NICHD Rensselear Polytechnic Institute

34 Grodin, Erica NIAAA Brown University

74 Hargrove, Passley NEI The George Washington University

53 Humble, Stewart NINDS University of Oxford, LSUHSC New Orleans

52 Hyun, Seong-In NIAID University of Maryland, College Park

71 Inwood, Sarah NIDDK Johns Hopkins University

2 Islam, Rafique NHLBI George Mason University

37 Jones, Michael NHLBI Michigan State University

32 Kesner, Andrew NIDA Johns Hopkins University

47 Kimmich, Sara NIMH University College London

99 LaBarre, Brenna NHGRI Boston University

88 Lee, Nathanael NINDS Georgetown University

89 Leshem, Jasmin NCI Technion-Israel Institute of Technology

75 Levy, Emily NHLBI The George Washington University

59 Lingemann, Matthias NIAID Baunschweig University of Technology

46 Lotspeich-Cole, Leda NICHD Johns Hopkins University

30 Louis, Lydia NCI-DCEG Rutgers, The State University of New Jersey

3 Magen, Assaf NCI University of Maryland, College Park

48 Marler, Laura NICHD Johns Hopkins University

111 Marquart, Gregory NICHD University of Maryland, College Park

22 Martinez-Kaigi, Valeria NIMH University of North Texas

35 Matson, Matthew NIAID Marshall University Joan C. Edwards School of Medicine

77 Matus-Nicodemos, Rodrigo NIAID Johns Hopkins University

19 McCann, Katelyn NIAID University of Massachusetts Medical School

79 Michael, Helen NCI University of Maryland, College Park

87 Miller, Brendan NHGRI Johns Hopkins University

113 Miller, Stephanie NIMH University of Maryland, College Park

STUDENTS Listed alphabetically by name


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54 Mirzaeimoghri, Mona NHLBI University of Maryland, College Park

57 Mukhamedoza, Maryam NIAID Johns Hopkins University

7 Ng, Caleb NIAID University of Pennsylvania

100 Nguyen, Thien NINDS Georgetown University

50 Nixon-Abell, Jonathon NINDS University College London

103 Park, Kyemyung NIAID University of Maryland, College Park

83 Patange, Simona NCI University of Maryland, College Park

21 Patel, Keval NHLBI University of Cambridge

105 Phillips, Ryan NINDS University of New Hampshire

8 Pourshafie, Naemeh NINDS The George Washington University

51 Prescott, Stephanie NINR University of Virginia

45 Prestil, Ryan NINDS University of Cambridge

61 Richoz, Nathan NIAMS University of Cambridge

17 Roney, Joseph NINDS University of Oxford

104 Rubinstein, Dani NIMH Brown University

73 Russo, Matthew NINDS Johns Hopkins University

106 Saglam, Aybike NINDS University of Maryland, College Park

119 Samarjeet, Samar NHLBI Johns Hopkins University, School of Medicine

24 Sarigiannidis, Ioannis NIMH University College London

14 Schmidt, Keith NCI Utrecht University

15 Schneller, Jessica NHGRI SUNY Stony Brook

80 Sciascia, Nicholas NCI The George Washington University

10 Sengupta, Abhishek NEI University of Paris

90 Sengupta, Ayesha NIAAA University of Oxford

92 Sheikhbahaei, Shahriar NINDS University College London

4 Shivaprasad, Nityashree NCI Georgetown University

33 Shumway, Lukas NINDS Johns Hopkins University

36 Silverstein, Shana NIAAA University College London

115 Spurrier, Josh NINDS Johns Hopkins University

63 Starke, Carly Elizabeth NIAID Georgetown University

65 Stuart, Carey NIAID University of Maryland, College Park

107 Tisza, Michael NCI Johns Hopkins University

23 Tumas, Keyla NIAID Georgetown University

43 Velazquez-Kronen, Raquel NCI-DCEG University at Buffalo

16


60 Vemu, Annapurna NINDS Johns Hopkins University

101 Wang, Cuicui NIEHS Fudan Univerisity

42 Watson, Dionysios (Dennis) NCI University of Patras

28 Weaver, Kristen NINR New York University

40 Westwater, Margaret NIDDK University of Cambridge

96 Whitaker, D. Thad NEI Texas A&M University

76 Wong, Hiu-tung NIDCD Johns Hopkins University

78 Wong, Sing Wai NIEHS University of North Carolina at Chapel Hill

68 YAU, Ka Chun NICHD The Chinese University of Hong Kong

25 Yenkoidiok Douti, Lampouguin NIAID University of Maryland, College Park

67 Yolitz, Jason NIAID Johns Hopkins University

13 Young, Jennifer NCI University of Maryland, College Park

11 Zabala Alemán, Gabriela NIMH Universidad Central del Caribe


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1What Lies Beneath: Exposing Hidden Single-strand Breaksthrough Transcriptional PausesAllison Dennis and David J. ClarkGraduate Student Name: Allison DennisNIH Institute-Center: NICHDNIH and University Research Advisor: Dr. David J. ClarkGraduate University: Johns Hopkins University

2Structure Function Studies of Apolipoprotein A-I Mimetic Peptides for Cardiovascular Disease TherapyRafique M. Islam, Denis Sviridov, Scott Gordon and Alan RemaleyGraduate Student Name: Rafique M. IslamNIH Institute-Center: NHLBINIH Research Advisor: Dr. Alan T. RemaleyUniversity Research Advisor: Dr. Ancha BaranovaGraduate University: George Mason University

3Investigating T Cell Differentiation Using Single Cell TranscriptomesAssaf Magen, Thomas Ciucci, Sridhar Hannenhalli and Remy BosselutGraduate Student Name: Assaf MagenNIH Institute-Center: NCINIH Research Advisor: Dr. Remy BosselutUniversity Research Advisor: Dr. Sridhar HannenhalliGraduate University: University of Maryland, College Park

4FGFR4 Specific Chimeric Antigen Receptor (CAR) T Cell Therapy Against RhabdomyosarcomaNityashree Shivaprasad, Ying Xiong, Dina Schneider, Darong Wu, Joon-Yong Chung, Marielle Yohe, Jack Shern, Jun Wei, Zhongyu Zhu, Dimiter Dimitrov, Stephen Hewitt, Poul Sorensen, Rimas Orentas and Javed KhanGraduate Student Name: Nityashree ShivaprasadNIH Institute-Center: NCINIH Research Advisors: Dr. Javed Khan and Dr. Rimas OrentasUniversity Research Advisor: Dr. Anton WellsteinGraduate University: Georgetown University

5Molecular Determination of Biomolecules on the Surface of NanoparticlesBrian J. Caffrey, Daithi Garry and Kenneth DawsonGraduate Student Name: Brian J. CaffreyNIH Institute-Center: NCINIH Research Advisor: Dr. Sriram SubramaniamUniversity Research Advisor: Prof. Kenneth DawsonGraduate University: University College Dublin

6Transcranial Application of A2A Receptor Agonists Ameliorates Mild Traumatic Brain InjuryKara N. Corps, Kenneth Jacobson and Dorian B. McGavernGraduate Student Name: Kara N. CorpsNIH Institute-Center: NINDSNIH Research Advisor: Dr. Dorian B. McGavernUniversity Research Advisor: Dr. John CullenGraduate University: North Carolina State University

7Potential Autoimmune Consequences of Outlier T Cell Responses Driven by Small Gene Expression ChangesCaleb E. Ng, Harikesh Wong and Ronald N. GermainGraduate Student Name: Caleb E. NgNIH Institute-Center: NIAIDNIH Research Advisor: Dr. Ronald N. GermainGraduate University: University of Pennsylvania

8MiR-298 Counteracts Mutant Androgen Receptor Toxicity in Spinal and Bulbar Muscular AtrophyNaemeh Pourshafie, Philip R. Lee, Ke-lian Chen, George G. Harmison, Laura C Bott, Masahisa Katsuno, Gen Sobue, Barrington G. Burnett, Kenneth H. Fischbeck and Carlo RinaldiGraduate Student Name: Naemeh PourshafieNIH Institute-Center: NINDSNIH Research Advisor: Dr. Kenneth FischbeckUniversity Research Advisor: Dr. Norman LeeGraduate University: The George Washington University

9Mechanotransduction and Transcription Factor DynamicsDavid A. Garcia Grisales, Diego Presman and Gordon HagerGraduate Student Name: David A. Garcia GrisalesNIH Institute-Center: NCINIH Research Advisor: Dr. Gordon HagerUniversity Research Advisor: Dr. Arpita UpadhyayaGraduate University: University of Maryland, College Park

10Red-shifted Channelrhodopsin Stimulation Restores Light Responses in Blind Mice, Macaque Retina and Human RetinaAbhishek Sengupta, Antoine Chaffiol, Emilie Macé, Romain Caplette, Mélissa Desrosiers, Maruša Lampi, Valérie Forster, Olivier Marre, John Lin, José-Alain Sahel, Serge Picaud, Deniz Dalkara, Jens Duebel and Wei LiGraduate Student Name: Abhishek SenguptaNIH Institute-Center: NEINIH Research Advisor: Dr. Wei LiUniversity Research Advisor: Prof. Jens DuebelGraduate University: University of Paris 06

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11Differential Roles of Dopamine in the Striatum and the Amygdala in Reinforcement LearningGabriela M. Zabala Alemán, Johann F. Du Hoffmann, Bruno B. Averbeck and Yogita ChudasamaGraduate Student Name: Gabriela M. Zabala AlemánNIH Institute-Center: NIMHNIH Research Advisor: Dr. Bruno B. AverbeckUniversity Research Advisor: Dr. Luis CubanoGraduate University: Universidad Central del Caribe

12Cisplatin-Induced Hearing Loss is Associated with Long-Term Drug Accumulation in the CochleaAndrew M. Breglio, Aaron Rusheen, Eric Shide, Katharine Fernandez, Lauren Amable and Lisa CunninghamGraduate Student Name: Andrew M. BreglioNIH Institute-Center: NIDCDNIH Research Advisor: Dr. Lisa CunninghamUniversity Research Advisor: Dr. Matthew J.A. WoodGraduate University: University of Oxford

13Family Matters in Li-Fraumeni Syndrome: Using Multiple Methods to Identify Relational Coping in CouplesJennifer Young, Norman Epstein, Allison Werner-Lin and Mark GreeneGraduate Student Name: Jennifer YoungNIH Institute-Center: NCINIH Research Advisor: Dr. Mark GreeneUniversity Research Advisor: Dr. Norman EpsteinGraduate University: University of Maryland, College Park

14The Effects of pH on the Physicochemical Properties of CRLX101 – A Novel Investigational Nanoparticle-Drug Conjugate (NDC)Keith T. Schmidt, Jessica Kindrick, Cody J. Peer and William D. FiggGraduate Student Name: Keith T. SchmidtNIH Institute-Center: NCINIH Research Advisor: Dr. William D. FiggUniversity Research Advisor: Dr. Jan H. SchellensGraduate University: Utrecht University

15Targeted Genome Editing Using CRISPR to Correct a Mouse Model of Methylmalonic Acidemia (MMA)Jessica L. Schneller, Ciaran M. Lee, Randy J. Chandler, Thomas J. Cradick, Gang Bao and Charles P. VendittiGraduate Student Name: Jessica L. SchnellerNIH Institute-Center: NHGRINIH Research Advisor: Dr. Charles P. VendittiGraduate University: State University of New York Stony Brook

16Prime and Target Immunization Protects Against Liver-Stage MalariaAnita Gola, Adam A. Walters, Stefan Uderhardt, Benedict R. Halbroth, Ahmed M. Salman, Shahid M. Khan, Chris J. Janse, Ronald N. Germain, Alexandra J. Spencer and Adrian V. HillGraduate Student Name: Anita GolaNIH Institute-Center: NIAIDNIH Research Advisor: Dr. Ronald N. GermainUniversity Research Advisor: Dr. Adrian V. HillGraduate University: University of Oxford

17Mechanisms Regulating Axonal Autophagosome-Lysosome Transport in the Glycosphingolipid Lysosomal Storage Disorder Niemann-Pick Type CJoseph C. Roney, Tamar Farfel-Becker, Xiu-Tang Cheng, Frances M. Platt and Zu-Hang ShengGraduate Student Name: Joseph C. RoneyNIH Institute-Center: NINDSNIH Research Advisor: Dr. Zu-Hang ShengUniversity Research Advisor: Professor Frances M. PlattGraduate University: University of Oxford

18Development of a Field-Based Point-of-Care Assay to Detect Antimalarial Drugs from Unprocessed Fingerstick Blood SamplesJoel Tarning, Maarten De Vos and Rick FairhurstGraduate Student Name: Erin CoonahanNIH Institute-Center: NIAIDNIH Research Advisor: Dr. Rick FairhurstUniversity Research Advisor: Dr. Maarten De Vos, Dr. Joel TarningGraduate University: University of Oxford

19The Regulation and Function of IRG1 in Human Monocytes and MacrophagesKatelyn J. McCann, Amy Hsu, Elizabeth Sampaio, Masashi Matsuyama, Anuj Kashyap and Steve HollandGraduate Student Name: Katelyn J. McCannNIH Institute-Center: NIAIDNIH Research Advisor: Dr. Steven HollandUniversity Research Advisor: Dr. Beth McCormickGraduate University: University of Massachusetts Medical School

20Autophagy in Artemisinin-Resistant Plasmodium FalciparumKimberly F. Breglio, Pharath Lim, Roberto Amato, David Roberts, Katja Simon and Rick FairhurstGraduate Student Name: Kimberly F. BreglioNIH Institute-Center: NIAIDNIH Research Advisor: Dr. Rick FairhurstUniversity Research Advisor: Dr. Katja SimonGraduate University: University of Oxford

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21Identifying the Location of the Water Permeability in Rat Mesenteric Artery Using CARS MicroscopyKeval D. Patel, Betrand Lucotte and Robert S. BalabanGraduate Student Name: Keval PatelNIH Institute-Center: NHLBINIH Research Advisor: Dr. Robert BalabanUniversity Research Advisor: Prof. Michelle OyenGraduate University: University of Cambridge

22Validating the NIH-Brief Fatigue Inventory Across Patient PopulationsValeria Martinez-Kaigi, Carlos Zarate, Rodrigo Machado-Vieira and David LuckenboughGraduate Student Name: Valeria Martinez-KaigiNIH Institute-Center: NIMHNIH Research Advisor: Dr. Carlos ZarateUniversity Research Advisor: Dr. Charles GuarnacciaGraduate University: University of North Texas

23Characterizing the Role of T Regulatory Cells in Rodent Malaria InfectionsKeyla Tumas, Jian Wu, Norinne Lacerda Quieroz and Xin-Zhuan SuGraduate Student Name: Keyla TumasNIH Institute-Center: NIAIDNIH Research Advisor: Dr. Xin-Zhuan SuGraduate University: Georgetown University

24Time Also Flies When You are Not Having Fun: The Impact of Induced Anxiety on Time PerceptionIoannis Sarigiannidis, Monique Ernst, Christian Grillon, Jonathan Roiser and Oliver RobinsonGraduate Student Name: Ioannis SarigiannidisNIH Institute-Center: NIMHNIH Research Advisor: Dr. Christian Grillon, Dr. Monique ErnstUniversity Research Advisor: Dr. Jonathan Roiser, Dr. Oliver RobinsonGraduate University: University College London

25Assessing the Potential of Plasmodium P47 as a Malaria Transmission Blocking VaccineLampouguin Y. Douti, Gaspar Canepa and Carolina Barillas-MurryGraduate Student Name: Lampouguin Y. DoutiNIH Institute-Center: NIAIDNIH Research Advisor: Dr. Carolina Barillas-MuryUniversity Research Advisor: Dr. Christopher JewellGraduate University: University of Maryland, College Park

26Characterizing Fos-expressing Neuronal Ensembles Associated with Amphetamine Sensitization in Rat Nucleus AccumbensRebecca Fallon, F. Javier Rubio, Brandon Warren and Bruce HopeGraduate Student Name: Rebecca FallonNIH Institute-Center: NIDANIH Research Advisor: Dr Bruce HopeGraduate University: Johns Hopkins University

27Creation and Characterization of Stable HEK 293 Mutant Cell Lines with Increased Protein Expression Potential Using High Throughput siRNA Screening and CRISPR Gene EditingLaura I. Abaandou and Yossi ShiloachGraduate Student Name: Laura I AbaandouNIH Institute-Center: NIDDKNIH Research Advisor: Dr. Yossi ShiloachUniversity Research Advisor: Dr. BishopGraduate University: George Mason University

28Stress Perceptions, Physiological Correlates and Quality of Life, in Patients with Irritable Bowel SyndromeKristen R. Weaver, Gail D. Melkus, Jason Fletcher and Wendy A. HendersonGraduate Student Name: Kristen R. WeaverNIH Institute-Center: NINRNIH Research Advisor: Dr. Wendy A. HendersonUniversity Research Advisor: Dr. Gail D'Eramo MelkusGraduate University: New York University

29Using RNA guided Nucleases to Tag and Edit Type I Collagen in Order to Study Procollagen Trafficking in Murine OsteoblastsLaura Gorrell, Shakib Omari, Anna Roberts-Pilgrim, Elena Makareeva and Sergey LeikinGraduate Student Name: Laura GorrellNIH Institute-Center: NICHDNIH Research Advisor: Dr. Sergey LeikinUniversity Research Advisor: Dr. Mariah HahnGraduate University: Rensselear Polytechnic Institute

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30Personal Use of Organochlorine Insecticides and Cancer Risks Among the Agricultural Health Study Farm SpousesLydia M. Louis, Catherine C. Lerro, Melissa C. Friesen, Gabriella Andreotti, Stella Koutros, Dale P. Sandler, Aaron Blair, Mark G. Robson and Laura E. Beane FreemanGraduate Student Name: Lydia M. LouisNIH Institute-Center: NCI-DCEGNIH Research Advisor: Dr. Laura Beane Freeman and Dr. Melissa FriesenUniversity Research Advisor: Dr. Mark RobsonGraduate University: Rutgers, The State University of New Jersey

31Investigating CD4 Lineage Differentiation in the ThymusLaura B. Chopp and Rémy BosselutGraduate Student Name: Laura B. ChoppNIH Institute-Center: NCINIH Research Advisor: Dr. Rémy BosselutUniversity Research Advisor: Dr. Rémy BosselutGraduate University: University of Pennsylvania

32Optogenetic Dissection of a Novel Reward CircuitAndrew J. Kesner and Satoshi IkemotoGraduate Student Name: Andrew J. KesnerNIH Institute-Center: NIDANIH Research Advisor: Dr. Satoshi IkemotoGraduate University: Johns Hopkins University

33Exploring the Interactions Between the Extracellular Domains of NMDA and AMPA Receptors and NeuroliginsLukas J. Shumway and Katherine RocheGraduate Student Name: Lukas J. ShumwayNIH Institute-Center: NINDSNIH Research Advisor: Dr. Katherine RocheUniversity Research Advisor: N/AGraduate University: Johns Hopkins University

34The Neural Correlates of Aversion Resistant Alcohol SeekingErica N. Grodin, Kelsy Sundby, Lauren Sussman, Grace Brennan, Vijay Ramchandani, Markus Heilig and Reza MomenanGraduate Student Name: Erica N. GrodinNIH Institute-Center: NIAAANIH Research Advisor: Dr. Reza MomenanGraduate University: Brown University

35Ebola Virus Disease (EVD) and Bacterial Co-InfectionM. Jeremiah Matson, Vincent J. Munster and Daniel S. ChertowGraduate Student Name: M. Jeremiah MatsonNIH Institute-Center: NIAIDNIH Research Advisor: Dr. Vincent J. MunsterUniversity Research Advisor: Dr. Hongwei D. YuGraduate University: Marshall University Joan C. Edwards School of Medicine

36Neural Circuits Underlying Vicariously Learned FearShana E. Silverstein, Olena Bukalo, Abby Postle, Aaron Limoges and Andrew HolmesGraduate Student Name: Shana E. SilversteinNIH Institute-Center: NIAAANIH Research Advisor: Dr. Andrew HolmesUniversity Research Advisor: Dr. Essi VidingGraduate University: University College London

37Structure, Activity, and Chemical Recognition of pH and Ionic Strength Induced Protein-Protein InteractionsMichael R. Jones, Bernard. R. Brooks and Angela K. WilsonGraduate Student Name: Michael R. JonesNIH Institute-Center: NHLBINIH Research Advisor: Dr. Bernard R. BrooksUniversity Research Advisor: Dr. Angela K. WilsonGraduate University: Michigan State University

38Hunger-Driven Motivational State CompetitionC. Joseph Burnett, Chia Li, Emily Webber, Eva Tsaousidou, Stephen Y. Xue, Jens C. Bruning and Michael J. KrashesGraduate Student Name: C. Joseph BurnettNIH Institute-Center: NIDDKNIH Research Advisor: Dr. Michael J. KrashesGraduate University: Brown University

39Interrogating the Selective Vulnerability of Neuronal Subpopulations in FTD and ALSMichael S. Fernandopulle and Michael E. WardGraduate Student Name: Michael S. FernandopulleNIH Institute-Center: NINDSNIH Research Advisor: Dr. Michael E. WardUniversity Research Advisor: Prof. Peter St. George-HyslopGraduate University: University of Cambridge, Northwestern University Feinberg School of Medicine

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40Functional Integration of Homeostatic and Visual Signals in the Obese StateMargaret L. Westwater, W. Kyle Simmons, Alex Martin and Kevin D. HallGraduate Student Name: Margaret L. WestwaterNIH Institute-Center: NIDDKNIH Research Advisor: Dr. Kevin HallUniversity Research Advisor: Prof. Paul FletcherGraduate University: University of Cambridge

41Formulation of Vaccines With Self-Assembled Nucleic Acid Adjuvants to Promote Tumor ImmunityNeil M. Dold, Lorena Parlea, Joost J. Oppenheim, Bruce A. Shapiro and Christopher M. JewellGraduate Student Name: Neil M. DoldNIH Institute-Center: NCINIH Research Advisor: Dr. Bruce A. ShapiroUniversity Research Advisor: Dr. Christopher M. JewellGraduate University: University of Maryland, College Park

42Extracellular Vesicles for Tumor-Enhanced Delivery of Immunotherapy: Overcoming Barriers in Production, Purification and DeliveryDionysios C. Watson, Defne Bayik, Avinash Srivatsan, Bryant Yung, Cristina Bergamaschi, Jenifer Bear, Aizea Morales-Kastresana, Jennifer C. Jones, Barbara K. Felber, Xiaoyuan Chen, Ihsan Gursel and George N. PavlakisGraduate Student Name: Dionysios C. WatsonNIH Institute-Center: NCINIH Research Advisor: Dr. George N. PavlakisUniversity Research Advisor: Dr. George Z. PanosGraduate University: University of Patras, Greece

43Radiation-Related Health Risks Associated with Protracted Low-Dose Occupational Radiation Exposure in U.S. Radiologic TechnologistsRaquel Velazquez-Kronen, Cari Kitahara, Martha Linet, Kirsten Moysich and Ethel GilbertGraduate Student Name: Raquel Velazquez-KronenNIH Institute-Center: NCI-DCEGNIH Research Advisor: Dr. Cari KitaharaUniversity Research Advisor: Dr. Kirsten MoysichGraduate University: University at Buffalo

44Directional Migration of Cancer Cells In Response to a Stiffness Gradient is Potentiated by Rapid Protrusion and Retraction DynamicsBrian J. DuChez and Kenneth M. YamadaGraduate Student Name: Brian J. DuChezNIH Institute-Center: NIDCRNIH Research Advisor: Dr. Kenneth M. YamadaUniversity Research Advisor: Dr. Daniel BlairGraduate University: Georgetown University

45Investigating Dysregulated Autophagy in Spinal and Bulbar Muscular AtrophyRyan Prestil, Kenneth Fischbeck and David RubinszteinGraduate Student Name: Ryan PrestilNIH Institute-Center: NINDSNIH Research Advisor: Dr. Kenneth FischbeckUniversity Research Advisor: Prof. David RubinszteinGraduate University: University of Cambridge

46Ascorbate Mediated Translational Regulation of the GDP-L-Galactose Phosphorylase (GGP) EnzymeLeda E. Lotspeich-Cole and Thomas DeverGraduate Student Name: Leda Lotspeich-ColeNIH Institute-Center: NICHDNIH Research Advisor: Dr. Thomas DeverGraduate University: Johns Hopkins University

47Know Thy Brain, Change Thyself: Understanding the Neurocognition of Real Time NeurofeedbackSara Kimmich and Peter BandettiniGraduate Student Name: Sara KimmichNIH Institute-Center: NIMHNIH Research Advisor: Dr. Peter BandettiniUniversity Research Advisor: Prof. Geraint ReesGraduate University: University College London

4840S Ribosomal Protein Rps26 Plays a Critical Role in Accurate Start Codon Selection During Translation Initiation In VivoLaura Marler, Jyothsna Visweswaraiah and Alan G. HinnebuschGraduate Student Name: Laura MarlerNIH Institute-Center: NICHDNIH Research Advisor: Dr. Alan HinnebuschGraduate University: Johns Hopkins University

49Targeting Polyomaviruses Using Adoptive T Cell ImmunotherapySarah I. Davies, Pawel Muranski, Greg Whitehill, Keyvan Keyvanfar, Quan Yu, Mark Chang and A. John BarrettGraduate Student Name: Sarah I. DaviesNIH Institute-Center: NHLBINIH Research Advisor: Dr. A. John Barrett and Dr. Pawel MuranskiGraduate University: Georgetown University

50Increased Spatiotemporal Resolution Reveals Highly Dynamic Dense Tubular Matrices in the Peripheral ERJonathon Nixon-Abell, Christopher J. Obara, Aubrey V. Weigel, Dong Li, Wesley R. Legant, C. Shan Xu, H. Amalia Pasolli, Kristen Harvey, Harald F. Hess, Eric Betzig, Craig Blackstone and Jennifer Lippincott-SchwartzGraduate Student Name: Jonathon Nixon-AbellNIH Institute-Center: NINDSNIH Research Advisor: Dr. Craig BlackstoneUniversity Research Advisor: Prof Kirsten HarveyGraduate University: University College London

51Effects of Antibiotic Exposure During Parturition on Offspring Immune DevelopmentStephanie M. Prescott, Ernesto Perez-Chanona, Giorgio Trinchieri and Wendy HendersonGraduate Student Name: Stephanie M. PrescottNIH Institute-Center: NINRNIH Research Advisor: Dr. Giorgio Trinchieri, Dr. Wendy HendersonUniversity Research Advisor: Dr. Jessica Keim-Malpass, Dr. Donna SchminkeGraduate University: University of Virginia

52Vaccinia Virus Protein I2 is Required for a Critical Stage in Virus MorphogenesisSeong-In Hyun, Andrea Weisberg and Bernard MossGraduate Student Name: Seong-In HyunNIH Institute-Center: NIAIDNIH Research Advisor: Dr. Bernard MossUniversity Research Advisor: Dr. Jeff DeStefanoGraduate University: University of Maryland, College Park

53Elucidating the Role of Progranulin in FTD-associated Lysosomal DysfunctionStewart W. Humble and Michael E. WardGraduate Student Name: Stewart W. HumbleNIH Institute-Center: NINDSNIH Research Advisor: Dr. Michael E. WardUniversity Research Advisor: Prof. Richard Wade-MartinsGraduate University: University of Oxford, LSUHSC New Orleans

54Micro Fabrication of Hard X-ray Compound Refractive Lens Using Nanoprinting ProcessMona Mirzaeimoghri, Caroline MacCue, Eric Bennett, Alejandro Morales Martinez, Alireza Panna, Bertrand Lucotte, Don DeVoe and Han WenGraduate Student Name: Mona MirzaeimoghriNIH Institute-Center: NHLBINIH Research Advisor: Dr. Han WenUniversity Research Advisor: Dr. Don DeVoeGraduate University: University of Maryland, College Park

55An Investigation of Health Disparities in PainTroy C. Dildine, Andreas Olsson and Lauren Y. AtlasGraduate Student Name: Troy C. DildineNIH Institute-Center: NCCIHNIH Research Advisor: Dr. Lauren Y. AtlasUniversity Research Advisor: Dr. Andreas OlssonGraduate University: Karolinska Institutet

56Structural Basis for the Redox Regulation of the Human Molecular Chaperone HSP27T. Reid Alderson, Julien Roche, Heidi Y. Gastall, Iva Pritisanac, Ad Bax, Justin L. P. Benesch and Andrew J. BaldwinGraduate Student Name: T. Reid AldersonNIH Institute-Center: NIDDKNIH Research Advisor: Dr. Ad BaxUniversity Research Advisor: Profs. Andrew J. Baldwin and Justin L. P. BeneschGraduate University: University of Oxford

57Unbiased Evaluation of Antibody Repertoire using Heavy and Light Chain Linkage ReactionMaryam Mukhamedova, Brandon Dekosky, Daniel Douek and John MascolaGraduate Student Name: Maryam MukhamedovaNIH Institute-Center: NIAIDNIH Research Advisor: Dr. John MascolaGraduate University: Johns Hopkins University

58Contact Guidance During Breast Cancer Cell MetastasisSong Chen, Rachel Lee, Matt Hourwitz, John Fourkas, Wolfgang Losert and Carole A. ParentGraduate Student Name: Song ChenNIH Institute-Center: NCINIH Research Advisor: Dr. Carole A. ParentUniversity Research Advisor: Dr. Wolfgang LosertGraduate University: University of Maryland, College Park

59Development and Preclinical Evaluation of Live Attenuated Parainfluenza Virus Vectors expressing Ebola Virus Glycoprotein GP as Intranasal Ebola Vaccine CandidatesMatthias Lingemann, Xueqiao Liu, Sonja Surman, Bo Liang, Ursula J. Buchholz, Peter L. Collins and Shirin MunirGraduate Student Name: Matthias LingemannNIH Institute-Center: NIAIDNIH Research Advisor: Dr. Peter L. CollinsGraduate University: Baunschweig University of Technology

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60Tubulin Isoform Composition Tunes Microtubule DynamicsAnnapurna Vemu, Joseph Atherton, Jeffrey O. Spector, Carolyn Moores and Antonina Roll-MecakGraduate Student Name: Annapurna VemuNIH Institute-Center: NINDSNIH Research Advisor: Dr. Antonina Roll-MecakUniversity Research Advisor: Dr. Antonina Roll-MecakGraduate University: Johns Hopkins University

61The TL1A-DR3 Axis in Immune Complex-Mediated NephritisNathan Richoz, Françoise Meylan, Taylor K. Farley, Menna R. Clatworthy and Richard M. SiegelGraduate Student Name: Nathan RichozNIH Institute-Center: NIAMSNIH Research Advisor: Dr. Richard M. SiegelUniversity Research Advisor: Dr. Menna R. ClatworthyGraduate University: University of Cambridge

62Chromatin Remodeling in Motor Neuron DevelopmentJustin Demmerle, Carson J. Miller, Ezequiel Miron, David Pinto, Ian M. Dobbie, Lothar Schermelleh and Todd S. MacfarlanGraduate Student Name: Justin DemmerleNIH Institute-Center: NICHDNIH Research Advisor: Dr. Todd S MacfarlanUniversity Research Advisor: Dr. Lothar SchermellehGraduate University: University of Oxford

63Functionality of Tissue-Resident SIV-Specific CD8+ T CellsCarly Elizabeth C. Starke and Jason M. BrenchleyGraduate Student Name: Carly Elizabeth C. StarkeNIH Institute-Center: NIAIDNIH Research Advisor: Dr. Jason M. BrenchleyGraduate University: Georgetown University

64Overexpression, Purification, and Characterization of a Membrane-bound Receptor for PEDFJeanee Bullock and S. Patricia BecerraGraduate Student Name: Jeanee BullockNIH Institute-Center: NEINIH Research Advisor: Dr. S. Patricia BecerraGraduate University: Georgetown University

65Analysis of Vaccinia Virus Intermediate Transcription Factors and their OrthologsCarey A. Stuart, Linda S. Wyatt and Bernard MossGraduate Student Name: Carey A. StuartNIH Institute-Center: NIAIDNIH Research Advisor: Dr. Bernard MossUniversity Research Advisor: Dr. Jeffrey DeStefanoGraduate University: University of Maryland, College Park

66Characterization of Btbd7 Expression and Function In Vivo and In VitroJoshua W. Collins, William P. Daley and Kenneth M. YamadaGraduate Student Name: Joshua W. CollinsNIH Institute-Center: NIDCRNIH Research Advisor: Kenneth M. YamadaUniversity Research Advisor: Trina SchroerGraduate University: Johns Hopkins University

67The Anti-gp120 mAb CH58 Recognizes a Not-Fully-Processed form of Surface-Expressed EnvJason Yolitz, Danlan Wei, Donald Van Ryk, Claudia Cicala, Anthony S. Fauci and James ArthosGraduate Student Name: Jason YolitzNIH Institute-Center: NIAIDNIH Research Advisor: Dr. James ArthosGraduate University: Johns Hopkins University

68Controlling the Ran Pathway at Anaphase OnsetKa Chun. Yau, Alexei Arnaoutouv and Mary DassoGraduate Student Name: Ka Chun. YauNIH Institute-Center: NICHDNIH Research Advisor: Dr. Mary DassoUniversity Research Advisor: Dr. K.P. FungGraduate University: The Chinese University of Hong Kong

69Elucidating the Mechanism Of Piperaquine Resistance in Plasmodium Falciparum Malaria in CambodiaMegan R. Ansbro, Pharath Lim, Chanaki Amaratunga, Hendrik W. van Veen, Marcus C. Lee and Rick M. FairhurstGraduate Student Name: Megan R. AnsbroNIH Institute-Center: NIAIDNIH Research Advisor: Dr. Rick FairhurstUniversity Research Advisor: Dr. Hendrik van VeenGraduate University: University of Cambridge

70Local Pulsatile Contractions are an Intrinsic Property of the Myosin 2A Motor in the Cortical Cytoskeleton of Adherent CellsMichelle A. Baird, Neil Billington, Aibing Wang, Robert S. Adelstein, James R. Sellers, Robert S. Fischer and Clare M. WatermanGraduate Student Name: Michelle A. BairdNIH Institute-Center: NHLBINIH Research Advisor: Dr. Clare M. WatermanUniversity Research Advisor: Dr. Kimberly StrokaGraduate University: University of Maryland, College Park

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71Improving Production of Retroviral Vector From PG13 Cells for T Cell TherapySarah, Inwood, Hui Xu, Steven Feldman, Michael J. Betenbaugh and Joseph ShiloachGraduate Student Name: Sarah InwoodNIH Institute-Center: NIDDKNIH Research Advisor: Dr. Joseph ShiloachUniversity Research Advisor: Dr. Michael J. BetenbaughGraduate University: Johns Hopkins University

72Frmpd1: A Novel Gene Involved in Rod Photoreceptor MaturationChristie K. Campla, Jung-Woong Kim, Hyun-Jin Yang, Jerome E. Roger, Lijin Dong, Stephanie Halford, Sumathi Sekaran and Anand SwaroopGraduate Student Name: Christie K. CamplaNIH Institute-Center: NEINIH Research Advisor: Dr. Anand SwaroopUniversity Research Advisor: Dr. Stephanie Halford, Dr. Sumathi SekaranGraduate University: University of Oxford

73Distinct Myeloid Cell Subsets Promote Angiogenesis and Damaged Tissue Clearance Following Mild Traumatic Brain InjuryMatthew V. Russo and Dorian B. McGavernGraduate Student Name: Matthew V. RussoNIH Institute-Center: NINDSNIH Research Advisor: Dr. Dorian B. McGavernUniversity Research Advisor: Dr. Rejji KuruvillaGraduate University: Johns Hopkins University

74Defining the Role of Rabgef1 in Vertebrate PhotoreceptorsHyun-Jin Yang, Jung-Woong Kim and Anand SwaroopGraduate Student Name: Passley HargroveNIH Institute-Center: NEINIH Research Advisor: Dr. Anand SwaroopUniversity Research Advisor: Dr. Sally MoodyGraduate University: The George Washington University

75Functional Characterization of Genetically Modified NK Cells Expressing Gain-of-Function CXCR4 ProteinEmily Levy, Robert Reger, Mattias Carlsten and Richard ChildsGraduate Student Name: Emily LevyNIH Institute-Center: NHLBINIH Research Advisor: Richard ChildsUniversity Research Advisor: Linda WerlingGraduate University: The George Washington University

76Regulation of Hair-cell Ribbon Synapse Size by Mitochondrial Calcium StoresHiu-tung Candy Wong and Katie KindtGraduate Student Name: Hiu-tung Candy WongNIH Institute-Center: NIDCDNIH Research Advisor: Katie KindtGraduate University: Johns Hopkins University

77HLA-A and HLA-B Down-Modulation in HIV-Infected Cells Occurs Late in the Viral Replicative CycleRodrigo Matus-Nicodemos and Daniel DouekGraduate Student Name: Rodrigo Matus-NicodemosNIH Institute-Center: NIAIDNIH Research Advisor: Dr. Richard KoupGraduate University: Johns Hopkins University

78Optineurin Deficiency Causes Paget’s Disease of the Bone by Increasing OsteoclastogenesisSing-Wai Wong, Henry C. Tseng, Wenjing Pan, Ching-Chang Ko and Jennifer MartinezGraduate Student Name: Sing-Wai WongNIH Institute-Center: NIEHSNIH Research Advisor: Dr. Jennifer MartinezUniversity Research Advisor: Dr. Ching-Chang KoGraduate University: University of North Carolina at Chapel Hill

79Clinical and Genomic Characterization of a UV-induced BRAF V600E Mouse Model of Human MelanomaHelen T. Michael, Chi-Ping Day, Howard Yang, Maxwell Lee and Glenn MerlinoGraduate Student Name: Helen T. MichaelNIH Institute-Center: NCINIH Research Advisor: Glenn MerlinoUniversity Research Advisor: Siba SamalGraduate University: University of Maryland, College Park

80Assessing the Physiological Role of Endogenous DNA Double Strand Breaks at Gene PromotersNicholas Sciascia, Andres Canela and Andre NussenzweigGraduate Student Name: Nicholas SciasciaNIH Institute-Center: NCINIH Research Advisor: Dr. Andre NussenzweigUniversity Research Advisor: Dr. Norman LeeGraduate University: The George Washington University

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81A Systems Genetics Approach Reveals a Novel Rnaseh2c-Immune Response Axis that Affects Metastasis Severity in Breast CancerSarah K. Deasy and Kent W. HunterGraduate Student Name: Sarah K. DeasyNIH Institute-Center: NCINIH Research Advisor: Dr. Kent W. HunterUniversity Research Advisor: Dr. Norman LeeGraduate University: The George Washington University

82A Novel Mechanism for Growth Cone Motility: In Situ Live Imaging Suggests that Mesoscopic Organization of Actin Controls Axon Growth and GuidanceAkanni Clarke, Ramakrishnan Kannan, Phil McQueen, Victor Wang, Tyler Buckley, Hsiao Yu Fang, Stephen Wincovitch, Irina Kuzina and Edward GinigerGraduate Student Name: Akanni ClarkeNIH Institute-Center: NINDSNIH Research Advisor: Dr. Edward GinigerUniversity Research Advisor: Dr. Sally MoodyGraduate University: The George Washington University

83Single Molecule Analysis of Transcription in Live Cells Reveals the Gene Regulatory Function of MYC In VivoSimona Patange, Michelle Girvan, David Levens and Daniel R. LarsonGraduate Student Name: Simona PatangeNIH Institute-Center: NCINIH Research Advisor: Dr. Daniel R. LarsonUniversity Research Advisor: Dr. Michelle GirvanGraduate University: University of Maryland, College Park

84WNT Stimulation Dissociates a Frizzled 4 Inactive State Complex with Ga12/13Elisa Arthofer, Belma Hot, Julian Petersen, Katerina Strakova, Stefan Jaeger, Manuel Grundmann, Evi Kostenis, J Silvio Gutkind and Gunnar SchulteGraduate Student Name: Elisa ArthoferNIH Institute-Center: NICHDNIH Research Advisor: Dr. Tamas Balla (Dr. J. Silvio Gutkind)University Research Advisor: Dr. Gunnar SchulteGraduate University: Karolinska Institute

85Predicting Patients Response to Preoperative Chemo-Radiation Therapy in Rectal CancerNoam Auslander and Thomas ReidGraduate Student Name: Noam AuslanderNIH Institute-Center: NCINIH Research Advisor: Dr. Thomas ReidUniversity Research Advisor: Dr. Eytan RuppinGraduate University: University of Maryland, College Park

86Dopamine Potently Inhibits GABAergic Collateral Transmission in the Nucleus AccumbensDennis A. Burke and Veronica A. AlvarezGraduate Student Name: Dennis A. BurkeNIH Institute-Center: NIAAANIH Research Advisor: Dr. Veronica A. AlvarezGraduate University: Brown University

87Emergence of a Pan-Cancer CpG Island Methylator Phenotype and Unraveling its Underlying Molecular CommonalityBrendan F. Miller, Francisco Sanchez-Vega and Laura ElnitskiGraduate Student Name: Brendan F. MillerNIH Institute-Center: NHGRINIH Research Advisor: Dr. Laura ElnitskiUniversity Research Advisor: Dr. James TaylorGraduate University: Johns Hopkins University

88Investigating the Role of Fibrinogen and Iron in Inflammatory Demyelination Using Combined High-resolution MRI and Histopathology in Marmoset Experimental Autoimmune EncephalomyelitisNathanael J. Lee, Seung-Kwon Ha, Nicholas J. Luciano, Emily C. Leibovitch, Jennifer Lefeuvre, Matthew K. Schindler, Pascal Sati, Katerina Akassoglou, Afonso C. Silva, Steven Jacobson and Daniel S. ReichGraduate Student Name: Nathanael J. LeeNIH Institute-Center: NINDSNIH Research Advisor: Dr. Daniel S. ReichUniversity Research Advisor: Dr. Jeffrey HuangGraduate University: Georgetown University

89Combining Local Immunotoxins Targeting Mesothelin with CTLA-4 Blockade Synergistically Eradicates Murine Cancer by Promoting Anti-Cancer ImmunityYasmin Leshem, Xiu-fen Liu, Tapan Bera, Masaki Terabe, Jay A Berzofsky, Birgit Bossenmaie, Gerhard Niederfellner, James O'Brien, Chin-Hsien Tai, Yoram Reiter and Ira PastanGraduate Student Name: Yasmin LeshemNIH Institute-Center: NCINIH Research Advisor: Dr. Ira PastanUniversity Research Advisor: Dr. Yoram ReiterGraduate University: Technion-Israel Institute of Technology

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90Serotonergic Modulation of the Basolateral Amygdala and Fear LearningAyesha Sengupta, Marco Bocchio, David Bannerman, Marco Capogna, Trevor Sharp and Andrew HolmesGraduate Student Name: Ayesha SenguptaNIH Institute-Center: NIAAANIH Research Advisor: Dr. Andrew HolmesUniversity Research Advisor: Prof. Trevor Sharp, Prof. David BannermanGraduate University: University of Oxford

91Mutant IL-7Ra and Mutant NRAs are Sufficient to Induce T-Cell Acute Lymphoblastic Leukemia/LymphomaSarah D. Cramer, Julie A. Hixon, Caroline Andrews, Ross J. Porter, Gisele Rodrigues, Xiaolin Wu, Tim Back, Kelli Czarra, Helen Michael, Maggie Cam, Emilee Senkevitch, Peter D. Aplan, Wenqing Li and Scott K. DurumGraduate Student Name: Sarah D. CramerNIH Institute-Center: NCINIH Research Advisor: Dr. Scott K. DurumUniversity Research Advisor: Dr. Siba SamalGraduate University: University of Maryland, College Park

92Astrocytes Contribute to Homeostatic Control of Breathing at Rest and During ExerciseShahriar Sheikhbahaei, Egor Turovsky, Sergey Kasparov, Jeffrey C. Smith and Alexander V. GourineGraduate Student Name: Shahriar SheikhBahaeiNIH Institute-Center: NINDSNIH Research Advisor: Dr. Jeffrey C. SmithUniversity Research Advisor: Prof. Alexader V. GourineGraduate University: University College London

93A SRM Based Targeted Proteomics Strategy to Quantify Potential Markers of TKI Response in Lung CancerShivangi Awasthi, Tapan Maity and Xu ZhangGraduate Student Name: Shivangi AwasthiNIH Institute-Center: NCINIH Research Advisor: Dr. Udayan GuhaUniversity Research Advisor: Dr. David R. GoodlettGraduate University: University of Maryland, Baltimore

94An Integral Membrane Phospholipid Phosphate Phosphatase, PLPPR1, Overcomes Chondroitin Sulfate Inhibition and Regulates Neuronal PlasticityChinyere Agbaegbu Iweka, Panpan Yu, Caitlin Mencio, Sharada Tilve, Hero Katagiri and Herbert M. GellerGraduate Student Name: Chinyere Agbaegbu IwekaNIH Institute-Center: NHLBINIH Research Advisor: Dr. Herbert M GellerUniversity Research Advisor: Dr. Jeffrey UrbachGraduate University: Georgetown University

95Comprehensive Analysis of the Dynamics of Aberrant WNT Signaling on Global Gene Expression and Higher Order Nuclear StructureMarkus Brown, Laura Seaman, Darawalee Wangsa, Haiming Chen, Yue Hu, Indika Rajapakse and Thomas RiedGraduate Student Name: Markus BrownNIH Institute-Center: NCINIH Research Advisor: Dr. Thomas RiedUniversity Research Advisor: Dr. Eytan RuppinGraduate University: University of Maryland, College Park

96The Genetic Basis of Photoreceptor Synaptic Terminal StructureD. Thad Whitaker, Passley Hargrove, Hannah Fann, Amal Alsufyani, Matthew J. Brooks, Soo-Young Kim and Anand SwaroopGraduate Student Name: D. Thad WhitakerNIH Institute-Center: NEINIH Research Advisor: Dr. Anand SwaroopUniversity Research Advisor: Dr. Michael SmothermanGraduate University: Texas A&M University

97Using Variation Graphs to Improve Somatic Structural Variant DetectionErik Garrison, Richard Durbin and Stephen ChanockGraduate Student Name: Eric T. DawsonNIH Institute-Center: NCI-DCEGNIH Research Advisor: Dr. Stephen ChanockUniversity Research Advisor: Prof. Richard DurbinGraduate University: University of Cambridge

98Permeabilization-Free Antibody Labeling of the Olfactory Bulb for Correlative Serial Block-Face Scanning Electron MicroscopyKara Fulton and Kevin L. BriggmanGraduate Student Name: Kara A. FultonNIH Institute-Center: NINDSNIH Research Advisor: Dr. Kevin L. BriggmanGraduate University: Brown University

99Finding Hidden SNPs in Bushmen Genome Methylation DataBrenna A. LaBarre and Laura L. ElnitskiGraduate Student Name: Brenna A. LaBarreNIH Institute-Center: NHGRINIH Research Advisor: Dr. Laura L. ElnitskiGraduate University: Boston University

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100Differences in Phosphorylation of Neuroligins: 4X vs. 4YThien A. Nguyen, Michael A. Bemben, Yan Li and Katherine W. RocheGraduate Student Name: Thien A. NguyenNIH Institute-Center: NINDSNIH Research Advisor: Dr. Katherine RocheUniversity Research Advisor: Dr. Daniel PakGraduate University: Georgetown University

101Acute Inflammation Effects of Personal Exposures to Fine-Particulate Air Pollution may be Mediated by MethylationCuicui Wang, Renjie Chen, Min Shi, Jing Cai, Jingjin Shi, Changyuan Yang, Huichu Li, Zhijing Lin, Xia Meng, Cong Liu, Yue Niu, Yongjie Xia, Zhuohui Zhao, Haidong Kan and Clarice R. WeinbergGraduate Student Name: Cuicui WangNIH Institute-Center: NIEHSNIH Research Advisor: Dr. Clarice R. WeinbergUniversity Research Advisor: Dr. Haidong KanGraduate University: Fudan Univerisity

102Multi-channel MRI Array Coils for Imaging the Brain and Spinal Cord of Common MarmosetsWen-Yang Chiang, Cecil Chern-Chyi Yen, Jennifer Lefeuvre, Nick Luciano, Joseph Murphy-Boesch, Mary McDougall, Daniel Reich, Pascal Sati and Afonso SilvaGraduate Student Name: Wen-Yang ChiangNIH Institute-Center: NINDSNIH Research Advisor: Dr. Afonso SilvaUniversity Research Advisor: Dr. Mary McDougallGraduate University: Texas A&M University

103Exploring Information Transmission in Gene Networks Using Stochastic Simulation and Machine LearningKyemyung Park, Thorsten Prustel, Manikandan Narayanan, Yong Lu, Andrew J. Martins and John S. TsangGraduate Student Name: Kyemyung ParkNIH Institute-Center: NIAIDNIH Research Advisor: Dr. John S. TsangUniversity Research Advisor: Dr. Doron LevyGraduate University: University of Maryland, College Park

104Spatio-Temporal Alterations in Working Memory-Related Neural Activity in Schizophrenia while On and Off Antipsychotic MedicationDani Y. Rubinstein, Daniel P. Eisenberg, Frederick W. Carver, Tom Holroyd, Daniel R. Weinberger, Jose A. Apud, Richard Coppola and Karen F. BermanGraduate Student Name: Dani Y. RubinsteinNIH Institute-Center: NIMHNIH Research Advisor: Dr. Karen F. BermanUniversity Research Advisor: Dr. David L. SheinbergGraduate University: Brown University

105Sources of Intracellular Calcium Transients and Amplitude Modulation in the Respiratory Pre-Bötzinger ComplexRyan S. Phillip and Jeffrey SmithGraduate Student Name: Ryan S. PhillipsNIH Institute-Center: NINDSNIH Research Advisor: Dr. Jeffrey SmithUniversity Research Advisor: Dr. Bill HersmanGraduate University: University of New Hampshire

106Pleasing Astrocytes: What is the Secret of OECs?Aybike Saglam and Susan WrayGraduate Student Name: Aybike SaglamNIH Institute-Center: NINDSNIH Research Advisor: Dr. Susan WrayUniversity Research Advisor: Dr. Ricardo AranedaGraduate University: University of Maryland, College Park

107Packaging and Horizontal Transfer of Cellular DNA by Animal VirusesMichael J. Tisza, Valery Bliskovsky, Diana V. Pastrana and Christopher B. BuckGraduate Student Name: Michael J. TiszaNIH Institute-Center: NCINIH Research Advisor: Dr. Christopher B. BuckGraduate University: Johns Hopkins University

108No Change in ABC Transporter Expression Between Sclerotic and Non-Sclerotic Drug Resistant Epilepsy TissueLora D. Weidner, Pavitra Kannan, Nicholas Mitsios, Matthew D. Hall, William H. Theodore, Robert B. Innis and Jan MulderGraduate Student Name: Lora D. WeidnerNIH Institute-Center: NIMHNIH Research Advisor: Dr. Robert InnisUniversity Research Advisor: Dr. Jan MulderGraduate University: Karolinska Institutet

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109Hemodynamic Changes During N-backTaskHadis Dashtestani, Afrooz Anderson Azari, Nader Shahni Karamzadeh and Amir GandjbakhcheGraduate Student Name: Hadis DashtestaniNIH Institute-Center: NICHDNIH Research Advisor: Dr. Amir GandjbakhcheUniversity Research Advisor: Dr. Milton HalemGraduate University: University of Maryland, Baltimore County

110Cell-Specific Differential Expression of ErbB4 Isoforms in Brain Detected by BaseScope – a Novel In Situ Hybridization TechniqueLarissa M. Erben, Ming-Xiao He, Mindy Wang, Emily Park and Andres BuonannoGraduate Student Name: Larissa M. ErbenNIH Institute-Center: NICHDNIH Research Advisor: Dr. Andres BuonannoUniversity Research Advisor: Prof. Dr. Andreas Zimmer Graduate University: University of Bonn

111A Neuroanatomic Atlas of the Larval Zebrafish Brain Derived from Computational Analysis of Gene ExpressionGregory D. Marquart, Sinisa Pajevic, Alison Heffer and Igor B. DawidGraduate Student Name: Gregory D. MarquartNIH Institute-Center: NICHDNIH Research Advisor: Dr. Harold A. BurgessUniversity Research Advisor: Dr. Jens HerberholzGraduate University: University of Maryland, College Park

113Oscillations and Neuronal Avalanche Shape in Spontaneous Cortical ActivityShan Yu and Dietmar PlenzGraduate Student Name: Stephanie R. MillerNIH Institute-Center: NIMHNIH Research Advisor: Dr. Dietmar PlenzUniversity Research Advisor: Dr. Rajarshi RoyGraduate University: University of Maryland, College Park

115Cdk5 Dysfunction Increases the Intrinsic Rate of AgingJosh Spurrier, Arvind Shukla and Ed GinigerGraduate Student Name: Josh SpurrierNIH Institute-Center: NINDSNIH Research Advisor: Dr. Ed GinigerUniversity Research Advisor: Dr. Haiqing ZhaoGraduate University: Johns Hopkins University

117Body Composition and Mortality Among Adults with Colorectal Cancer: the NIH-AARP Diet and Health StudyMaria Rosario B. Aguiluz-Abunto, Didier Chalhoub and Tamara HarrisGraduate Student Name: Maria Rosario B. Aguiluz-AbuntoNIH Institute-Center: NIANIH Research Advisor: Dr. Tamara HarrisUniversity Research Advisor: Dr. Didier ChalhoubGraduate University: University of Pittsburgh Graduate School of Public Health

119Parallel Implementation of P21 Periodic Boundary Condition in CHARMMSamar Samarjeet, Thomas Woolf and Bernard Brooks Graduate Student Name: Samar SamarjeetNIH Institute-Center: NHLBINIH Research Advisor: Dr. Bernard BrooksUniversity Research Advisor: Dr. Tom WoolfGraduate University: Johns Hopkins University, School of Medicine

POSTERS

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Program of EventsGPP Graduation Award RecipientsKeynote SpeakerStudent SpeakersOutstanding Mentor Award RecipientsStudentsPostersBack Cover

13th annual nih graduate student research …...the symposium poster session, and we acknowledge the...

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