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Mutiara Medika

Edisi Khusus Vol. 8 No. 2: 89 - 95, Oktober 2008

Efikasi Binahong (Anredera cordifolia (Tenore) Steenis) terhadap

Kadar Alkaline Phosphatase

Efficacy Binahong (Anredera Cordifolia (Tenore) Steenis) Leaf

to Alkaline Phosphatase Level

1Salmah Orbayinah, 2Adhita Kartyanto1Bagian Biokimia Fakultas Kedokteran Universitas Muhammadiyah Yogyakarta,2Fakultas Kedokteran Universitas Muhammadiyah Yogyakarta

Abstract

Role of Binahong (Anredera cordifolia (Ten.) Steenis) leaves as hepatoprotector and

antioxidant was identified on CCl4 induced white rats.Unrandomized control trial method was used in this study. Ten male Wistar white rats

with 200 250 gr of body weight were divided into two groups. Group I as a control group

was treated with standard food and 1 ml aquadest orally for 12 days. Group II as a treatment

group was given standar food and daily single dose pretreatment of Binahong (Anredera

cordifolia (Ten.) Steenis) leaves juice 289,8 mg/200 gr of body weight for 12 days. Carbon

tetrachloride (1 ml/kg body weight, i.p.) injected into rats in the day 13th to induce liver cells

damage. ALP test used ALP KIT reagent had been done twice, 1 stday and 14th day.

The result shows mean of ALP level before and after treatment in control group were

95,94+1,52 and 110,15+1,07; in treatment group were 92,65+3,05 and 92,91+0,68. PairedT-test shown significant difference before and after treatment (p