1 IN3ADULTS WORLDWIDEHAS HIGH BLOOD PRESSURE

That’s over1.2billion people

High blood pressure is implicated in13% of all deaths worldwide

WHAT IS HIGHBLOOD PRESSURE?

HIGH BLOOD PRESSUREsystolic: 140 mmHg or higherdiastolic: 90 mmHg or higher

AT RISK (prehypertension)systolic: 120-139 mmHgdiastolic: 80-89 mmHg

NORMAL BLOOD PRESSUREsystolic: less than 120 mmHgdiastolic: less than 80 mmHg

High blood pressure, also known ashypertension, occurs when bloodpressure in the arteries is elevated,requiring the heart to work harderthan normal to circulate bloodthroughout the body.

WHAT ARE THE HEALTH RISKS?Patients with resistant hypertension (high blood pressure that does not

respond to a combination of at least three treatment drugs) are threetimes more at risk for cardiac events like heart attack or stroke.

of first-time heart attack sufferers have high blood pressure

69% 74%of people with chronic heart failure have high blood pressure

of first-time stroke sufferers have high blood pressure

77%

WHAT ARE THE COSTS?

HOW IS IT TREATED?Physicians may prescribe medicationand recommend other lifestylechanges such as: losing weight,stopping smoking, reducing sodiumintake and engaging in regularexercise.

RENAL DENERVATION – A NEW HOPE

Infographic courtesy of St. Jude MedicalSources: WHO; Centers for Disease Control, Heart Disease and Stroke Statistics – 2012 update: a report from the American Heart Association; Resistant Hypertension: Diagnosis Evaluation and Treatment – A report from the American Heart Association; HHS Secretary Sebelius statement on National High Blood Pressure Education Month; Cleveland Clinic; Persell, Stephen D. “Prevalence of Resistant Hypertension in the United States, 2003-2008.” Hypertension 57.6; Lawes CM, et al. International Society of Hypertension -Global burden of blood-pressure related disease, Lancet: 2008;371

Renal denervation is a new frontier in medicine. Currently,there are several research studies taking place to learn more about thispromising new therapy.

Preliminary clinical data from EnligHTN I trial at six months has found that, on average, after renal denervation, systolic blood pressure reduction of 26 mmHg was sustained.

Renal denervation is a medical procedure that may be a treatmentoption for patients with chronic hypertension.

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For every 20 point decrease in systolic blood pressure, the risk of cardiovascular death is cut in in half.

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Overactive nerve signals in the renal arteries that lead to and from the kidneys are a contributing factor to hypertension. Renal denervation intentionally disrupts nerve signals that are thought to cause high blood pressure.

people worldwide are treatment resistantwhere at least three high blood pressure drugs do not work.

100 million

$

Annual global health care expenditure directly related to hypertension was estimated atalmost €385 billion Euros every year.

13%