1st year mbbs curriculum (3rd module)
TRANSCRIPT
1
1st Year MBBS Curriculum
(3rd Module)
CMH INSTITUTE OF MEDICAL SCIENCES (CIMS)
BAHAWALPUR
2
Sr. No. Topics Page No.
1. Calendar of 1st Year MBBS Class 4
2. Weekly Time Table 5
3. Module Theme 6
4. Teaching Hours 8
5.
Department of Anatomy
a. Faculty
b. Recommended books
c. General Anatomy
d. Embryology
e. Histology
f. Gross Anatomy (upper limb)
g. Histology (Practical)
9
10
11
13
17
18
21
6.
Department of Physiology
a. Faculty
b. Recommended books
c. Lectures
23
24
25
3
d. Practical 30
7.
Department of Biochemistry
a. Faculty
b. Recommended books
c. Lectures
d. Practical
33
34
35
39
4
CALENDAR OF 1ST YEAR MBBS CLASS (2018 / 2019)
Events Class
1st Year
Start of Session 06 Feb 2019 (Wed)
1st Module
Duration: 10 Week
From: 06 Feb 2019(Wed)
To: 21 April 2019 (Sun)
End Module Exam: 15 April 2019 (Mon) To 21 April 2019 (Sat)
2nd Module
Duration: 10 Week
From: 22 April 2019 (Mon)
To: 21 July 2019 (Sun)
End Module Exam: 15 July 2019 (Mon) To 20 July 2019 (Sat)
3rd Module
Duration: 08 Week
From: 22 July 2019 (Mon)
To: 29 Sep 2019 (Sun)
End Module Exam: 14 Sep 2019 (Sat) To 20 Sep 2019 (Fri)
Sports Week 25 March 2019 (Mon) To 29 March 2019 (Fri)
There will be ½ day Activity in the morning before sports activities
Summer Vacation & Eid ul Fitr Leave 18 May 2019 (Sat) To 16 June 2019 (Sun) (30 Days)
Eid ul Azha Leave 10 Aug 2019 (Sat) To 18 Aug 2019 (Sun) (09 Days)
Prep Leave Pre-Annual Exam 21 Sep 2019 (Sat) To 27 Sep 2019 (Fri) (07 Days)
Pre-Annual Exam 28 Sep 2019 (Sat) To 05 Oct 2019 (Sat)
Prep Leave Annual Exam 06 Oct 2019 (Sun) To 31 Oct 2019 (Thur) (26 Days)
Annual Exam 01 Nov 2019 (Fri) To 16 Nov 2019 (Sat)
Post Prof Leave 17 Nov 2019 (Sun) To 24 Nov 2019 (Sun) (08 Days)
5
WEEKLY TIME TABLE
1st YEAR MBBS CLASS (THIRD MODULE)
2018 / 2019
Days 0800-0930 0935-1030 1030-
1100 1105-1200 1205-1300
1300-
1315 1315-1500
Mon
Demo &
Dissection
Gross Anatomy
Physiology
Lecture
TE
A B
RE
AK
General Anatomy
Lecture
Biochemistry
Lecture
PR
AY
ER
BR
EA
K
Batch-A
Practical
Anatomy
Batch-B
Practical
Physio
Batch-C
Practical
Biochem
Tue
Demo &
Dissection
Gross Anatomy
Physiology
Lecture
Embryology
Lecture
Biochemistry
Lecture
Batch-A
Practical
Biochem
Batch-B
Practical
Anatomy
Batch-C
Practical
Physio
Wed
Demo &
Dissection
Gross Anatomy
Physiology
Lecture
Histology
Lecture
Biochemistry
Lecture
Batch-A
Practical
Physio
Batch-B
Practical
Biochem
Batch-C
Practical
Anatomy
Thurs
Demo &
Dissection
Gross Anatomy
Physiology
Lecture Clinical Physiology Clinical Anatomy
Batch-1
Tutorial (Physio)
Batch-2
Tutorial (Biochem)
Fri
Demo &
Dissection
Gross Anatomy
Batch-1
Tutorial (Biochem)
Batch-2
Tutorial (Physio)
Physiology
Lecture Islamiat Lecture
1300-1400
FRI PRAYER
1400-1500
Behavioral Sciences
6
MODULE THEME
BLOCKS THEMES
ANATOMY PHYSIOLOGY BIOCHEMISTRY
1. Lower Limb 2. Respiratory System
1. Lower Limb 2. Respiratory System
Learning outcomes
ANATOMY PHYSIOLOGY BIOCHEMISTRY
Gross anatomy
Lower Limb General Anatomy
Skin Fascia
Vertebral column
Nervous system-II Embryology
Birth defects
Body cavities
Respiratory system
Muscular System
Skeletal system except head and neck
Development of limbs Histology
Respiratory system
Physiology of respiration
Deep sea physiology
Aviation/space physiology
High altitude physiology Exercise physiology
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MODULE THEME
Code Y1M3
Name Anatomy
Duration 10 weeks
Broad Themes of Module (Theme: a subject that is being integrated a majority of time of module)
Lower Limb Respiratory System
Subject Themes
Gross anatomy
Lower Limb General Anatomy
Skin Fascia Vertebral column Nervous system-II Embryology
Birth defects Body cavities Respiratory system Muscular System Skeletal system except head and neck Development of limbs Histology Respiratory system
Prerequisite Module Y1M1 & Y1M2
8
TEACHING HOURS
Total Weeks/Hours: 8 weeks/ 280 Hours (0800-1500)
Anatomy :
o Demos : 40 5/Week 60 hours
o practical: 08 1/Week 36 hours
o Histo Lectures: 08 1/Week 8 Hours
o Embryo Lectures : 08 1/Week 8 Hours
o GA Lectures : 08 1/Week 8 Hours
Total 120 hours
Physiology :
o Lectures : 40 5/Week 40 Hours
o Practical: 08 1/Week 36 Hours
Total 76 hours
Biochemistry :
o Lectures : 24 3/Week 24 hours
o practical: 08 1/Week 36 hours
Total 60 hours
CBLs :
o CBLs : 8 1/Week 12 hours
Med Education: 4 hours
Medicine: 4 hours
Surgery: 4 hours
Radiology: 2 hours
9
DEPARTMENT OF ANATOMY
S.No Faculty Course
1. Professor: Dr. Fareed Alvi Histology
2. Associate Professor: Dr. Alina Saqib Embryology
3. Assistant Professor: Dr. Fareha Shan General Anatomy
Lecturers
1. Dr. Asima Kashif Gross Anatomy
2. Dr. Ayesha Nasrullah Gross Anatomy
3. Dr. Rabbia Farooq Gross Anatomy
4. Dr. Abdullah Histology practical
5. Dr.Fareha Asghar Gross Anatomy
10
RECOMMENDED BOOKS (ANATOMY)
Gross Anatomy
o Cunningham’s Manual of Practical Anatomy vol. I- 15th edition, 1986.
o Clinical Anatomy by Regions. Richard S. Snell, 9th edition, 2012.
o Netter Atlas of Human Anatomy. 5th edition 2011.
o Reference Books
Clinically Oriented Anatomy. Keith L Moore, 6th edition, 2010.
Gray’s Anatomy. 40th edition, 2008.
General Anatomy
o General Anatomy. Dr. Laiq Hussain, 3rd edition, 2011.
o Understanding General Anatomy. Professor Tassaduq Hussain, 14th edition, 2014.
Embryology
o Langman’s Medical Embryology. 12th edition, 2012.
Histology
o Medical Histology. Dr. Laiq Hussain, 5th edition, 2015. o Reference Books
Basic Histology. Junqueira, 13th edition, 2013.
DiFiore’s Atlas of Histology. 12th edition, 2013.
Manual/Practical Copies
o Histology Manual by Prof Athar Maqbool
o Gross Anatomy – Plain Copy (Sketch Book)
11
ANATOMY
Third Module (1 x Lecture / Week) Subject: General Anatomy
Lectures Week General Anatomy Learning Objectives
1. I. Skin
Describe the components of integumentary system.
List the functions of integumentary system
List the two main parts of skin.
List its layers with their general features.
2. II. Facia
Name appendages of skin.
Describe their general features.
Define cleavage lines? Describe their clinical importance.
3. III. Vertebral column Describe the anatomy of vertebral column with reference to:
Number of vertebrae in different regions
4. IV. Defects of vertebral column. Name different types of defects of vertebral column
Describe defects in the curvature of vertebral column
5. V. Nervous system-I
Describe division of nervous system on gross anatomical basis
Name components of central and peripheral nervous system.
Describe their general features
Define autonomic nervous system (ANS). Enlist the differences between
autonomic and somatic nervous system
6. VI. Autonomic nervous system
List the main divisions of ANS? Describe differences of its two main
divisions in tabulated form.
Explain cranial parasympathetic ganglia.
Describe their general features.
12
7. VII. Autonomic nervous system II Define enteric nervous system.
List general features.
13
ANATOMY
Third Module (1 x Lecture / Week) Subject: Embryology
Lectures Week Embryology Learning Objectives
1. I.
Birth defects
Name types of birth abnormalities & define each of them with at least one example
describe principles of teratology
Classify teratogens with associated human malformations in tabulated form
List numerical & structural chromosomal abnormalities
Discuss the following numerical chromosomal abnormalities:
Trisomy 21
Trisomy 18
Trisomy 13
Klinefelter syndrome
Turner syndrome
2. II.
Development of body
cavities
Explain transformation of single intraembryonic coelom into pericardial, pleural and
peritoneal cavities
List development sources of diaphragm
Describe development of diaphragm
Discuss positional changes of diaphragm with reference to age of fetus
Explain the innervation of diaphragm with reference to its developmental sources
Analyze clinical scenarios regarding:
Ventral body wall defects
Diaphragmatic hernias
3. III.
Development of
respiratory system
Describe the development of the following:
Larynx
Trachea
Bronchi
Lungs
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Describe different stages of lung maturation
List factors responsible for normal lung maturation
List the postnatal changes that occur in lungs
Analyze clinical scenarios regarding:
Various types of tracheoesophageal fistulas
Respiratory distress syndrome
4. IV.
Development of
skeletal system
Describe histogenesis of cartilage
Describe histogenesis of bone
Explain development of joints
Describe development of vertebral column
Define spina bifida. Enlist its different types. Give embryological basis of bifid spine
alongwith methods of prenatal assessment in this anomaly
Explain development of ribs and sternum with congenital defects
Discuss embryological basis and associated birth defects of:
Klippel feil syndrome
Accessory ribs
Fused ribs
Hemivertebra
Rachiscisis
15
5. V.
Development of
muscular system
Describe development of skeletal musculature
Define lateral somitic frontier. List the structures whose borders are defined by lateral
somitic frontier.
Enumerate the muscles derived from primaxial and abaxial domains
recognize the innervation of axial skeletal muscles
List the developmental source of:
Head muscles
Limb muscles
Cardiac muscles
Smooth muscles
Discuss the following clinical anomalies:
Poland sequence
Prune belly syndrome
6. VI.
Development of limbs
Describe the formation of limb buds
Define apical ectodermal ridge and discuss its role in limb development including digits
Describe limb growth and development
Discuss rotation of limbs during development. Describe the relationship between rotation
of limbs & cutaneous nerve supply of limbs
Differentiate between development of upper and lower limbs
7. VII.
Limb defects and
chromosomal
abnormalities
Discuss development of limb musculature
Describe the various types of limb defects.
Explain their embryological basis
Discuss the following structural chromosomal abnormalities:
Cri-du-chat syndrome
Angelman’s syndrome
Prader-willi syndrome
Miler-dieker syndrome
Define mosaicism & discuss its embryological basis
Describe critical periods of prenatal human development
16
Name invasive and noninvasive approaches for assessing growth & development of fetus
in utero
17
ANATOMY
Third Module (1 x Lecture / Week) Subject: Histology
Lectures Week Histology Learning Objectives
1. I. Respiratory system
List the main divisions of respiratory passage along with the structures
constituting each
2. II.
Respiratory and olfactory
epithelium
Define respiratory and olfactory epithelium
List the cells comprising respiratory & olfactory epithelium.
3. III.
Nasopharynx Describe extension, epithelium, mucosa, and muscles of nasopharunx
4. IV. Larynx Describe histological structure of nasopharynx
Explain the layer of larynx
5. V. Trachea, Bronchi
Differentiate various parts of bronchial tree on the basis of lining epithelium,
presence of cilia, glands, cartilage, smooth muscles, and elastic fibers
6. VI. Phrynx Describe the extension and histological features of phrynx
7. VII. Pleura, Lungs
Explain the layers of plura
Describe the Epithelium and stroma of pleura
Differentiate various parts of bronchial tree on the basis of lining epithelium,
presence of cilia, glands, cartilage, smooth muscles, and elastic fibers
18
ANATOMY
Third Module (5 x Demos / Week) Subject: Gross Anatomy (Lower Limb)
Lectures Week Topics
1.
I.
Hip bone
2. Gluteal Region
3. Vasculature of Gluteal Region
4. Femur
5. Anterior fascial Compartment of Thigh
6. Medial fascial Compartment of Thigh
7. The back of the thigh
8.
SUBSTAGE -1
9. Gluteal Region
10. Thigh, Hip Bone, Femur
11.
II.
Hip joint
12. Bones of leg
13. Popliteal fossa
19
14. Fascial compartments of leg
15. Knee joint
16.
Proximal & distal Tibiofibular joints
17. SUBSTAGE – 2
18.
III.
Hip joint, Bones of leg
19. Popliteal fossa
20. Fascial compartments of leg
21.
IV.
Ankle joint
22. Articulated foot
23. Sole of foot
24. The dorsum of foot
25. Cutaneous innervations of lower limb
26.
V.
Blood supply of lower limb
27. SUBSTAGE – 3
28. Ankle joint, Foot, Knee joint
29. Cutaneous innervations of lower limb
20
30. Blood supply of lower limb
31.
VI.
Lymphatic drainage of lower limb
32. Surface marking
33. Final Stage
21
ANATOMY
Third Module (1 x Practical / Week) Subject: Histology Practical
S.No Week Practical Learning Objectives
1. I.
Respiratory system Skill:
Identify and draw the different parts of respiratory system.
Focus the prepared slide at different magnifications.
2. II.
Respiratory and olfactory
epithelium
Skill:
Identify respiratory and olfactory epithelium
Identify the different shapes of cells.
Draw a labeled diagram of different types of cells.
3. III.
Nasopharynx Skill:
Identify the epithelia of nasopharynx.
Draw a labeled diagram of different layers of nasophrynx.
4. IV.
Larynx Skill:
Identify the epithelia
Draw labeled diagram histological features of lyrnx.
Identify mucous and serousa with haematoxylin and eosin.
Draw a labeled diagram of layers of larynx
22
5. V.
Trachea, Bronchi
Skill:
Identify various parts of bronchial tree on the basis of lining epithelium, presence
of cilia, glands, cartilage, smooth muscles, and elastic fibers.
6. VI.
Phrynx Skill:
Identify different types of layers microscopically.
Draw a labeled diagram showing the histological structure of different types of
layers with hematoxylin and eosin.
7. VII. Pleura, Lungs
Skill:
Identify different types of layers microscopically.
Draw a labeled diagram showing the histologic structure of pleura.
Identify various parts of bronchial tree on the basis of lining epithelium, presence
of cilia, glands, cartilage, smooth muscles, and elastic fibers.
23
DEPARTMENT OF PHYSIOLOGY
S.No Faculty Course
1 Professor: Dr. Shafiq Ahmad Iqbal Lectures
2 Associate Professor: Dr. Rukhsana Mirza Lectures
3. Assistant Professor: Dr. Jazib Andleeb Lectures
4 Assistant Professor: Dr. Sara Sadiq Lectures
Lecturers
1 Dr. Khalid Mehmood Arif Practicals & Tutorials
2 Dr. Amber Javaid Practicals & Tutorials
3 Dr. Amna Riaz Practicals & Tutorials
24
RECOMMENDED BOOKS (PHYSIOLOGY)
Kim E. Barrett, Susain M.Barman Ganongls Review of Medical Physiology 24th Edition McGrowhill.
Bruce M.Koeppon, Bruce A.Stanton Berne & Cevy Physiology 6th Edition Raj Kamal Electric Press, Kundli, Haryana
ELSEVIER 2010.
John E. Hall Guyton & Hall Text Book of Medical Physiology 13th Edition Canada ELSEVIER 2016.
Lecture Notes Kaplan
USMLE step -1 Kaplan.
USMLE First Aid.
Fundamental / Introduction of biochemistry by Mackee Mackee.
25
PHYSIOLOGY
Third Module (5 x Lectures / Week, 1 Clinical Lecture / week for Vertical Integration)
Lectures Week Topics Learning Objectives
1.
I.
Introduction to Respiratory System I Describe the functional anatomy of respiratory tract
Describe the functions of various parts of respiratory system
Give the overall view of respiratory system in homeostasis.
2.
Pulmonary Mechanics I
Explain the non-respiratory functions of respiratory tract
Describe the functions of respiratory muscles.
3.
Pulmonary Mechanics I
Describe the role of different respiratory muscles during inspiration and
expiration
Describe the role of Bucket handle movement and Pump handle
movement in controlling the chest diameters.
4.
Pulmonary Mechanics II
Describe the various pressures acting on lungs and chest wall
Explain the change in pleural, alveolar and transpulmonary pressures
during each phase of respiration.
Define Compliance with its normal value for the lung and chest wall
compliance
Draw and label the compliance diagram
the concept of work of breathing
5. Surfactant role on surface tension
Describe the composition and synthesis of surfactant
Describe the role of surfactant in reducing alveolar surface tension
Describe the abnormalities relates to deficiency of surfactant
26
6.
II.
Lung Volumes and Capacities
Define Lung Volumes and Capacities along with its normal value
Explain the spirogram showing lung volumes and capacities
Differentiate between obstructive and restrictive lung disorders
7. Pulmonary Circulation
Describe the physiological anatomy of pulmonary vessels
Describe the pressures in pulmonary vessels
Describe the pressure differences b/w pulmonary & systemic circulation
8. Pulmonary Capillary dynamics
Describe the role of starling forces in maintenance of equilibrium across
the pulmonary capillary and interstitum
Explain the role of pulmonary safety factor to prevent edema
9.
Abnormalities of Pulmonary Capillary
dynamics
Describe the Pulmonary edema and Plural effusion along with its etiology
and pathophysiology.
10. Gas laws and Partial pressure of gases
Describe different gas laws
Explain the changes in partial pressure of gases from atmospheric air to
different phases of breathing
11.
III.
Respiratory Membrane & Diffusion of
Gases
Describe the structure and layers of respiratory membrane
Describe the diffusing capacity through respiratory membrane
Describe the factors affecting gas diffusion through respiratory
membrane
12.
Oxygen transport
List the forms of oxygen transport
Describe the mechanics of oxygen diffusion from blood to tissue fluid
Describe the mechanics of oxygen diffusion from tissue fluid in to cell
13. Oxygen-hemoglobin Dissociative curve
Explain the normal oxygen-hemoglobin dissociation curve
Explain the role of factors that shift oxygen-hemoglobin dissociation
curve
27
14.
Carbon dioxide transport
List the various chemical form in which CO2 is transported in blood
Explain the normal CO2 dissociation curve
Explain the concept of haldane effect
15. Hypoxia and Hypercapnia
Define Hypoxia and Hyper-capnia
Describe the types and causes of hypoxia
Describe the effect of hypoxia and hyper-capnia on body
various causes of hypoxia
To know the effects of hypoxia on the body
To study the role of oxygen therapy in different types of hypoxia
16.
IV.
Pulmonary circulation Va /Q
Describe ventilation perfusion ratio
Explain the concept of shunted blood
Describe the abnormalities of ventilation perfusion ratio in lung diseases
17.
Nervous regulation of respiration
List different group of neurons composing respiratory center
Describe the control of inspiration and respiratory rhythm
Explain the role of pneumotaxic center in respiration
Describe the regulatory mechanism of hering-breuer inflation reflex
18.
Chemical regulation of respiration
Describe the central chemosensitive area & its stimulation by CO2 and
H+
Explain the role of peripheral chemoreceptors for control of respiration
Describe the composite effects of PCO2, pH, & PO2 on alveolar
ventilation
19. Test ----
20.
Regulation of respiration during
exercise Describe oxygen consumption and pulmonary ventilation during exercise
Describe the respiratory changes during exercise
28
List the factors that control respiration during exercise
21.
V.
Abnormal breathing pattern
Describe the different Abnormal breathing pattern
Describe the mechanism of Cheyne-Stokes Breathing
Describe the types and mechanism of sleep apnea.
22. Arterial blood gases and pH
Explain the role of arterial blood gases and pH in diagnosis of different
lung abnormalities
23. Respiratory disease I
Define emphysema
Describe etiology and pathophysiology of emphysema
Describe the physiological effects of chronic emphysema
Define pneumonia and atelectasis
24. Respiratory disease II
Define pneumonia and atelectasis
Describe the etiology and pathophysiology of pneumonia and atelectasis
25. Respiratory disease III
Define tuberculosis and asthma
Describe the etiology and pathophysiology of tuberculosis and asthma
26.
VI.
Acclimatization at High altitude
Describe the mechanism of acclimatization of the body to low O2
List the cause of natural acclimatization in natives of High Altitude
Explain the principles of acclimatization
27.
Hazards at High Altitude
Describe the change in composition of air at high altitude
Describe the effects of low oxygen pressure on the body
Describe the change of alveolar PO2 at different elevations
28. Space physiology
Describe the effects of acceleratory forces on the body in aviation and
space physiology.
Describe physiological Challenges of Weightlessness (Microgravity)
29
29. Deep sea diving I
Describe the effect of high partial pressures of individual gases on the
body
Describe the Symptoms, etiology and pathophysiological mechanism
Decompression Sickness
30. Deep sea diving II
Describe the components, uses and mechanism of self-contained
underwater Breathing apparatus (scuba) diving
Explain the special physiological problems in submarines
31.
VII.
Test (FORMATIVE ASSESSEMENT) SEQ’s
32. Revision of Respiratory system Important topics / Muddy points will be discussed.
33. Revision of Respiratory system Important topics / Muddy points will be discussed.
34. Test (FORMATIVE ASSESSEMENT) SEQ’s
35. Test (FORMATIVE ASSESSEMENT) SEQ’s
36.
VIII.
Test (FORMATIVE ASSESSEMENT) SEQ’s
37. Test (FORMATIVE ASSESSEMENT) SEQ’s
38. Test (FORMATIVE ASSESSEMENT) SEQ’s
39. Test (FORMATIVE ASSESSEMENT) SEQ’s
40.
Assessment week Theory, OSPE & practical assessment.
30
PHYSIOLOGY
Third Module (1 x Practical / Week) Subject: Physiology Practical
Demonstration Week Practical Learning Objectives
1. I.
Examination of the chest related to respiratory system
Knowledge:
Describe the steps of examination of chest
List symptoms and signs of respiratory diseases
Skill:
Perform inspection, palpation, percussion and auscultation of respiratory system
2. II.
Auscultation of breath
sounds
Knowledge:
List the causes of abnormal breath sounds.
Skill:
Perform the Auscultation of breath sounds.
3. III.
Cardio Pulmonary Resuscitation
Knowledge:
Describe cardio Pulmonary arrest.
Describe the aims, indication and importance of Cardio Pulmonary Resuscitation.
Describe the ABC of Cardio Pulmonary Resuscitation.
Skill:
31
Perform Cardio Pulmonary Resuscitation on the subject.
4. IV.
Spirometry: Lung volumes
and capacities
Knowledge:
Define various respiratory volumes and capacities.
Describe variation in Lung volumes and capacities in case of obstructive and
restrictive diseases.
Skill:
Measure the Lung volumes and capacities by using Spirometer.
5. V.
Spirometry: FEV1 and
FVC
Knowledge:
Define various FEV1 and FVC
Describe variation in FEV1 and FVC in case of obstructive and restrictive
diseases.
Skill:
Measure the FEV1 and FVC by using Spirometer.
6. VI.
PEFR Peak Expiratory
Flow Rate
Knowledge:
Define Peak Expiratory Flow Rate
Describe the methodology of Peak Expiratory Flow Rate
Skill:
Perform Peak Expiratory Flow Rate by using peak flow meter
32
7. VII. Revision of practical’s -----
33
DEPARTMENT OF BIOCHEMISTRY
S.No Faculty Course
1. Professor: Dr. Jariya Kalsoom
Lecturers:
1. Dr. Ahmed Malik Practical’s
2. Dr. Rafia Nadeem Practical’s
3. Dr. Faisal Shahzad Practical’s
34
RECOMMANDED BOOKS (BIOCHEMISTRY)
Ser Author Of Book Title of Book Edition
1. Michael A. Lieberman Biochemistry Molecular Biology & Genetics 6th
2. Michael A. Lieberman Mark’s Essentials of Medical Biochemistry 2nd
3. Michael A. Lieberman Mark’s Basic Medical Biochemistry A Clinical Approach 4th
4. Stuart H. Ralston Davidson’s Principles and Practice of Medicine (Vol: 01) 23rd
5. Stuart H. Ralston Davidson’s Principles and Practice of Medicine (Vol: 02) 23rd
6. Maxine A. Papadakis Current Medical Diagnosis and Treatment (Vol: 01) 57th
7. Maxine A. Papadakis Current Medical Diagnosis and Treatment (Vol: 02) 57th
8. J Koolman K.H. Roehm Color Atlas of Biochemistry 2nd
9. Roger L. Miesfeld Biochemistry 1st
10. Kaplan Biochemistry and Medical Genetics 1st
11. Nalini Chandar Lippincott’s IIIustrated Reviews Cell and Molecular Biology 1st
12. Michael A. Lieberman Lippincott’s IIIustrated Q&A Review of Biochemistry 1st
13. Rebecca James Perumcheril Self Assessment and Review of Biochemistry 2nd
35
BIOCHEMISTRY
Third Module (4 x Lectures / Week) Subject: Biochemistry
Lecture Week Topics Learning Objectives
1.
I.
Classification of vitamins C
Classify vitamins
State RDA for vitamin C
List sources of vitamin C
Mention active form of vitamin C
Describe functions of vitamin C in body
Explain the biochemical basis anemia in vitamin C deficiency
Describe the causes and sign symptoms of scurvy
2.
Vitamin B2 riboflavin
State RDA for vitamin B2
List sources of vitamin B2
Mention active form of vitamin B2
Describe functions of vitamin B2in body Describe the causes and sign symptoms of deficiency of B2
3.
B9 Folic acid
State RDA for vitamin B9
List sources of vitamin B9
Mention active form of vitamin B9
Describe functions of vitamin B9 in body
Describe the causes and sign symptoms of deficiency of B9
Describe folate trap hypothesis Describe role of folate in one carbon metabolism
4.
B12 Cobalamine
State RDA for vitamin B12
List sources of vitamin B12
Mention active form of vitamin B12
Describe functions of vitamin B12 in body
Describe the causes and sign symptoms of deficiency of B12
Describe the absorption of B12
36
5.
II.
Vitamin B3 Niacin
State RDA for vitamin B3
List sources of vitamin B3
Mention active form of vitamin B3
Describe functions of vitamin B3 in body
Describe the causes and sign symptoms of deficiency of B3
6.
Vitamin B7 Biotin
Vitamin B6 Pyridoxine
State RDA for vitamin B7
List sources of vitamin B7
Mention active form of vitamin B7
Describe functions of vitamin B7 in body
Describe the causes and sign symptoms of deficiency of B7
State RDA for vitamin B6
List sources of vitamin B6
Mention active form of vitamin B6
Describe functions of vitamin B6 in body
Describe the causes and sign symptoms of deficiency of B6
7.
Vitamin B5 pantothenic acid
Vitamin B1 thiamine
State RDA for vitamin B5
List sources of vitamin B5
Mention active form of vitamin B5
Describe functions of vitamin B5 in body
Describe the causes and sign symptoms of deficiency of B5
State RDA for vitamin B1
List sources of vitamin B1
Mention active form of vitamin B1
Describe functions of vitamin B1 in body
Describe the causes and sign symptoms of deficiency of B1
8.
Vitamin A State RDA for vitamin A
List sources of vitamin A
Mention active form of vitamin A
Describe functions of vitamin A in body
Describe the causes and sign symptoms of deficiency of A
Describe the causes and sign symptoms of toxicity of vitamin A
37
9.
III.
Vitamin D State RDA for vitamin D
List sources of vitamin D
Mention active form of vitamin D
Describe functions of vitamin D in body
Describe the causes and sign symptoms of deficiency of D
Describe the causes and sign symptoms of toxicity of vitamin D
10.
Vitamin E State RDA for vitamin E
List sources of vitamin E
Mention active form of vitamin E
Describe functions of vitamin E in body
Describe the causes and sign symptoms of deficiency of E
Describe the causes and sign symptoms of toxicity of vitamin E
11.
Vitamin K State RDA for vitamin K
List sources of vitamin K
Mention active form of vitamin K
Describe functions of vitamin K in body
Describe the causes and sign symptoms of deficiency of K
Describe the causes and sign symptoms of toxicity of vitamin K
12.
Balanced diet & biochemical
importance of carbohydrates,
fats & protein in diet
Define balanced diet
Describe the biochemical importance of carbohydrates in diet
Describe the biochemical importance of proteins in diet
Describe the biochemical importance of lipids in diet
13.
IV.
RDA, BMR, Caloric
requirements
Define RDA and describe its biomedical importance
Define BMR and describe its biomedical importance
Identify caloric requirements for different age groups and physiological states
14.
Estimation of caloric
requirements
Estimation of caloric requirements
15.
Specific nutritional
requirements:
(Pregnancy, lactation,
newborn)
Explain specific nutritional requirements in: Pregnancy, lactation, newborn
Recommend diet plans for pregnant and lactating females and newborns
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16.
Carbohydrates & glycemic
index
Describe effect of carbohydrate rich diet on glycemic index
Define glycemic index
Describe biomedical importance of glycemic index
17.
V.
Proteins & nitrogen balance Describe the role of proteins in maintaining the nitrogen balance
Define nitrogen balance
18. Revisions ________
19. Revisions ________
20. Revisions ________
39
BIOCHEMISTRY
Third Module (1 x Practical / Week) Subject: Biochemistry
Demonstration Week Practical Learning Objectives
1.
I.
Physical & chemical properties of
urine
Knowledge:
Describe the physical and chemical properties of urine
Skill:
Interpretation of the physical and chemical properties of urine
2.
II.
Test for urine abnormalities
(benedict’s test, sulphosalicyclic
acid test & heat coagulation test)
Knowledge:
Describe the abnormalities of urine
Skill:
Detection of abnormalities in urine
3.
III.
Test for urine abnormal constituents
in urine (benedict’s test,
sulphosalicyclic acid test & heat
coagulation test)
Knowledge:
Describe the abnormal constituents in urine
Skill:
Detection of abnormal constituents in urine
4.
IV.
Tests for bio salts in urine
Knowledge:
Describe the significance of bio salts in urine
Skill:
Detection of bio salts in urine
40
5.
V.
Test for detection of bile pigments
in urine
Knowledge:
Describe the significance of bile pigments in urine
Skill:
Detection of bile pigments in urine
6.
VI.
Test for detection of ketone bodies
in urine
Knowledge:
Describe the significance of ketone bodies in urine
Skill:
Detection of ketone bodies in urine
7.
VII.
Test for detection of bilirubin in
urine
Knowledge:
Describe the significance of bilirubin in urine
Skill:
Detection of bilirubin in urine
8.
VIII.
Analyzing the urine report
Knowledge:
Describe the significance of urine report
Skill:
Interpretation of urine report