2004-2005Pharmacology Review

Drugs 1-100

April 18, 202308:35 PM

Abacavir

Antiretroviral

Nucleoside reverse transcriptase inhibitor (NRTI)

Abciximab

Antiplatelet

Anti-GPIIb/IIIa receptor antibody

Acarbose

Oral hypoglycemic

Alpha-glucosidase inhibitorInhibitor of intestinal glucose

absorption

Acebutolol

Sympatholytic1 adrenergic antagonistClass II antiarrhythmic

AntihypertensiveAntianginal

Bronchoconstrictor

Acetaminophen

Analgesic, Antipyretic

Acetazolamide

Diuretic

Carbonic anhydrase inhibitor

Acetylcholine

Cholinomimetic

AntigluacomaMuscle contraction (nicotinic

receptor)

Activated charcoal

Antidote

Acyclovir

Antiherpes

Purine analogPhosphorylated to inhibitor of

viral DNA polymerase

Adalimumab

TNF inhibitor

Anti-TNF antibodyUsed in rheumatoid arthritis

Adenosine

Antiarrhythmic

Miscellaneous(does not fit class I-IV organization)

Adrenocorticotropin(ACTH)

Anterior pituitary hormoneAnticonvulsant

Stimulates synthesisand release of cortisol

Albendazole

Antihelminthic

Treatment of intestinal roundworms

Albuterol

Sympathomimetic2 adrenergic agonist

Short acting bronchodilatorUsed in asthma

Aldosterone

AdrenocorticosteroidMineralocorticoid

Alemtuzumab

Antineoplastic

Anti-CD52 antibody

Alendronate

Anti-osteoporesis

BisphosphonateInhibitor of osteoclast-mediated

bone resorption

Alfentanil

OpioidGeneral anaesthetic

Intravenous anaesthetic

Allopurinol

AntigoutAntineoplastic (supporting

agent)

Folic acid analogueXanthine oxidase inhibitor

Alosetron

IBS treatment

5HT3 receptor antagonist

Alteplase

Thrombolytic

Tissue plasminogen activator (tPA)

Aluminum hydroxide

Antiulcer

Antacid

Amantadine

AntiviralAntiparkinson

Treatment of Influenza A Inhibits replication

at the stage of uncoatingInhibits dopamine release

Amikacin

Aminoglycoside antibioticBactericidal protein synthesis

inhibitor

30S ribosomeFreezes initiation

Amiloride

Potassium sparing diuretic

Sodium channel inhibitorAntihypertensive

Aminocaproic acid (EACA)

Procoagulant

Inhibitor of plasminogen activation

(decreases fibrinolysis)

Aminoglutethimide

AntineoplasticImmunosuppressive

Glucocorticoid antagonistAromatase inhibitor

(decreases steroid synthesis)

Aminoglycosides

AntibioticsBactericidal protein synthesis

inhibitors

30S ribosomeFreeze initiation

Aminophylline

Bronchodilator

MethylxanthinePhosphodiesterase inhibitor

Used in asthma

Amiodarone

Class I/III antiarrhythmic

Na+ and K+ channel blocker(inactivated channels)

Amitriptyline

Tricyclic antidepressant (TCA)

Amlodipine

Antihypertensive

Calcium channel blocker

Amoxicillin

Penicillin antibioticCell wall synthesis inhibitor

Antiulcer

Amino penicillinInhibits peptidoglycan cross-

linking

Amphetamine

Indirect sympathomimeticDrug of abuse

ADD treatmentStimulant

Ampicillin

Penicillin antibioticCell wall synthesis inhibitor

Amino penicillinInhibits peptidoglycan cross-

linking

Amphotericin B

AntifungalPolyene antibiotic

Binds to ergosterol and alters permeability

Systemic

Amsacrine

Antineoplastic

Miscellaneous

Amyl nitrite

Vasodilator

Antianginal Aerosol

Anastrozole

AntineoplasticAntiestrogen

Aromatase inhibitor

Angiotensin II

Autacoid

Vasoconstrictor

Anistreplase

Thrombolytic

Streptokinase + plasminogen

Anthraquinonescascara segrada, danthron, senna

Contact cathartics

Anti-thymocyte globulin

Immunosuppressive

Anti-T cell antibody

Aprepitant dimenhydrinate

Antiemetic

Neurokinin 1 receptor antagonist

Aprotinin

Procoagulant

Fibrinolytic inhibitorSerine protease inhibitor

(“serpin”)Streptokinase inhibitor

Arsenicals

Tropical antiparasitic

Treatment of African Trypanosomiasis in CNS

Melarsoprol

L-asparaginase

Antineoplastic

Protein synthesis inhibitor

Aspirin(Acetylsalicylic acid, ASA)

NSAID (acetylsalicylate)Analgesic, Anti-inflammatory

Antipyretic, Antiplatelet

Irreversible cyclooxygenase inhibitor

Aspart insulin

HormoneInsulin analogue

Ultra short acting

Atenolol

Sympatholytic1 adrenergic antagonist

AntihypertensiveAntiarrhythmic

AntianginalBronchoconstrictor

Atorvastatin

Antihyperlipidemic

HMG-CoA reductase inhibitor

Atovaquone

Antimalarial

Depolarizes parasitic mitochondria and inhibits

electron transport

Atracurium

Paralytic

Paralyzes skeletal muscles

Atropine

Anticholinergic

AntimuscarinicTreatment for bradycardia,

diarrhea, cholinesterase poisoning

Auranofin

Disease modifyinganti-rheumatic drug (DMARD)

Gold saltOral

Aurothioglucose

Disease modifyinganti-rheumatic drug (DMARD)

Gold saltParenteral

Azathioprine

ImmunosuppressiveAntineoplastic

Antimetabolite(“pseudofeedback inhibition” of

HGPRT and PRP)

Azithromycin

Macrolide antibioticBacteriostatic protein synthesis

inhibitor

50S ribosome Inhibits translocation

Aztreonam

New lactam antibiotic

Monobactam

Bacitracin

AntibioticCell wall synthesis inhibitor

Topical, not a lactam, Inhibits dephosphorylation of

bactoprenol

Baclofen

Skeletal muscle relaxantAnxiolytic

GABAB agonist

Balsalazide

NSAID (salicylate)

Treatment of IBD

Basiliximab

Immunosuppressive

Anti-CD25 (interleukin 2 receptor)

Organ transplant (antirejection)

Beclomethasone

AdrenocorticosteroidGlucocorticoid

Anti-inflammatory steroidInhaled

Benazopril

Antihypertensive

Converting enzyme inhibitor

Benzathine penicillin G

Penicillin antibioticCell wall synthesis inhibitor

Inhibits peptidoglycan cross-linking Repository preparation

Benztropine

AnticholinergicAntiparkinson

Muscarinic receptor antagonist

Betamethasone

AdrenocorticosteroidGlucocorticoid

Anti-inflammatory steroidNot by inhalation

Betaxolol

Sympatholytic1 adrenergic antagonist

AntihypertensiveGlaucoma medicationBronchoconstrictor

Bethanecol

Cholinomimetic

Muscarinic agonistInduces defecation and

urinationBronchoconstrictor

Bicalutamide

Antiandrogen

Androgen receptor antagonist

Biltolterol

Sympathomimetic2 adrenergic agonist

Bronchodilator

Bisacodyl

Contact cathartic

Bismuth subsalicylate

AntiulcerAntidiarrheal

Bispropolol

Sympatholytic adrenergic antagonist

AntihypertensiveBronchoconstrictor

Bivalirudin

Anticoagulant

Direct thrombin inhibitor (DTI)

Black cohosh

Dietary supplement

Relief of “hot flashes” and other menopausal symptoms

Bleomycin

Antineoplastic

Natural productAntibiotic

Botulinum toxin(Botox)

Paralytic

Paralyzes skeletal muscles

Bradykinin

Inflammatory mediator

Plasma, hypotension, pain

Bretylium

SympatholyticClass III antiarrhythmic

K+ channel blocker

Bromocriptine

Antiparkinson

Dopamine (D2) agonistInhibits prolactin release

Brupropion

Second generation antidepressant

Budesonide

AdrenocorticosteroidGlucocorticoid

Anti-inflammatory steroidInhaled OR treatment of IBD

Bumetanide

Loop diuretic

Na+-K+-2Cl- transporter inhibitor

Buprenorphine

Opioid

Partial agonist

Buspirone

Sedative/hypnoticAnxiolytic

Busulfan

Antineoplastic

Alkylating agent

Butorphanol

OpioidAnalgesic

receptor partial agonistor antagonist

C3a, C5a

Inflammatory mediators

Anaphylatoxins Low molecular weight

complement cleavage products

Calcium carbonate

Antiulcer

Antacid

Candesartan

Antihypertensive

Angiotensin receptor blocker(ARB)

Captopril

Antihypertensive

Converting enzyme inhibitor Heart failure treatmentAngioedema producer

Carbamazepine

Anticonvulsant

Carbenicillin

Penicillin antibioticCell wall synthesis inhibitor

Anti-pseudomonal penicillinInhibits peptidoglycan cross-

linking

Carbidopa

Antiparkinson

Peripheral dopa decarboxylase inhibitor

Carboprost

Oxytocic prostaglandin

Uterine stimulant

Carmustine (BCNU)

Antineoplastic

Alkylating agentNitrosourea

Carteolol

Sympatholytic adrenergic antagonist

AntihypertensiveBronchoconstrictor

Carvedilol

Sympatholytic adrenergic antagonist

Treatment for heart failure