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    Daniel J. Vreeman, PT, DPT, MScAssociate Research Professor

    , Indiana University School of Medicine

    Associate Director for Terminology Services, Regenstrief Institute, Inc

    2014

    Documents

    Clinical LOINC Meeting

    2014 09 04

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    Overview

    1. Origins of a Document Ontology

    2. HL7/LOINC Model

    3. Evaluation and Ongoing Development

    4. Future Directions

    photo via Vernio77

    http://www.flickr.com/photos/verino77/
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    http://loinc.org/slideshows

    http://loinc.org/slideshows
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    Origins of a DocumentOntology

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    Local systems have idiosyncratic names

    need a common, controlled vocabulary

    OutpatientPain

    Note

    Dr.SmithsTues

    PainClinic

    ChronicPain

    Clinic

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    Development Milestones

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    Document Type Codes

    Provide consistent semantics for names of documentsexchanged between systems for any purpose

    Frazier P, Rossi-Mori A, Dolin RH, Alschuler L, Huff SM. The creation of an ontology of clinical document names. Stud Health Technol Inform. 2001;84(Pt 1):94-8.

    Display Retrieval Organization Templates

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    What is a Document?a collection of information

    photo via striatic

    http://www.flickr.com/photos/striatic/
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    an information collection

    Title

    Sections

    Sentences

    Sentences

    Other content

    http://www.flickr.com/photos/karenhorton/http://www.flickr.com/photos/karenhorton/http://www.flickr.com/photos/karenhorton/
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    Different than a panelenumerated, discrete elements

    an information collection

    Title

    Sections

    Sentences

    Sentences

    Other content

    http://www.flickr.com/photos/karenhorton/http://www.flickr.com/photos/karenhorton/http://www.flickr.com/photos/karenhorton/
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    Clinical Notes

    Clinical Note

    Aclinicaldocument,producedbycliniciansspontaneouslyorinresponsetoarequestforconsultation.

    Clinical Report

    Aclinicaldocument,producedinresponsetoanorderforaprocedure.

    Formal Document Ontology model and rules apply

    to clinical notes, but not (yet) to reports.(although non-intuitively they are in CLASS:DOC.CLINRPT)

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    ApproachEmpiric analysis of >2000 documentnames

    Mayo, 3M/Intermountain, VA in SLC, VA in Nashville

    Find the level of granularity that best

    meets exchange use case

    Photo via Jeffrey Beall

    http://www.flickr.com/photos/denverjeffrey/
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    Ultra-specific local

    names Dr. Evils Friday Afternoon Pain

    Clinic Note

    Commonly understood

    elements

    Outpatient Pain Clinic Note

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    Local Codes and Names

    Still probably neededCan send both in HL7

    Mapping to a standard enables:Interoperability

    Aggregation

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    Document Ontology Model

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    Names are based on

    expected informationcontent

    NOTdocument format

    http://www.flickr.com/photos/karenhorton/http://www.flickr.com/photos/karenhorton/http://www.flickr.com/photos/karenhorton/http://www.flickr.com/photos/karenhorton/http://www.flickr.com/photos/karenhorton/http://www.flickr.com/photos/karenhorton/
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    Names Based on Content

    Same LOINC code for

    if information content is the same

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    Not Part of the Name

    AuthorLocation of service

    Date of service

    Status (e.g. signed, unsigned)

    Security/privacy flags (e.g. protected)

    Updates or amendments to a document

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    Assume that these other

    important attributes wouldbe sent in different fields of

    the message (e.g. metadata)

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    Domainofthecontentinthedocumente.g. Cardiology, Pediatric Cardiology, Physical Therapy

    Subject Matter Domain

    Authortraining/professionalclassification(not@subspecialty)e.g. Physician, Nurse, Case Manager, Therapist, Patient

    Role

    ModestextensionofCMSsdefinition(notequivalenttolocation)e.g. Hospital, Outpatient, Emergency Department

    Setting

    Serviceoractivityprovidedtopatiente.g. Consultation, History and Physical, Discharge Summary

    Type of Service

    Generalstructureofthedocumente.g. Note, Letter, Consent

    Kind of Document

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    Rules for

    constructing

    namesphoto via Robert S Donovan

    http://www.flickr.com/photos/booleansplit/
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    1. Enumerated List

    Documentnamesareconstructedfromenumeratedlists of values for each axis.

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    2. Document + One Other

    NamesneedtospecifyaKind of Documentvalueandatleastone of the other four axes.

    Component

    Property

    Find

    System

    Scale

    Doc

    Method

    .

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    3. Combinations

    Combinationsfromwithinanaxisare allowedwheretheyarereasonable(SMD,Service).

    Only a few examples currently:

    Assessment+Plan note

    Treatment plan+summary note

    Hematology+Medical oncology

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    Example LOINC Names

    {Curly Braces} notation:sendthatcontentasaseparateiteminthemessage(fieldorsegment).

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    LOINC Accessory FilesSpecial representations of LOINC content

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    Accessory Files

    LOINC Panels and Forms FileAn export of key panels, survey instruments, and forms in a

    detailed data structure.

    LOINC Multiaxial Hierarchy FileHierarchical organization of LOINC terms based on their axes.

    DocOnt terms are organized by Component (Type of Service)

    LOINC Document Ontology FileSpecial file for the detailed naming conventions for clinical

    document titles (e.g. Discharge Summary, Progress Note, etc).

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    Hierarchy in RELMA

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    Document Ontology File

    Links all Document Ontology terms to theirconstituent axis values

    Axis values given unique Part identifierscategorized by axis

    Available now!Downloads -> Accessory Files

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    Evolution + EvaluationWere not done yet

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    Iterative Evaluation

    Case StudyNYPH-CUMC

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    1. Expanded CDO is better

    2. Many local documents map to 1 LOINC

    3. Inter-rater reliability was good

    Case Study

    98.5%

    Hyun S, Shapiro JS, Melton G, Schlegel C, Stetson PD, Johnson SB, Bakken S. Iterative evaluation of the Health Level 7--Logical Observation Identifiers Names and Codes Clinical

    Document Ontology for representing clinical document names: a case report. J Am Med Inform Assoc. 2009 May-Jun;16(3):395-9.

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    Cross-site Mapping Study of DO AxesTerms whose titles specified this axis

    1. Majority of titles map to at least one axis

    2. Sites varied in how they specified titles; createsgranularity issues in cross-site aggregation

    Li L, Morrey CP, Baorto D. Cross-mapping clinical notes between hospitals: An application of the LOINC Document Ontology. AMIA Symp Proc; 2011:;777-783 .

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    The LOINC document ontology modelcan provide a robust representation of

    clinical documents. This can beexploited to assist in common namingconventions, finding notes by

    traversing the axis categories ofSubject, Setting, Role and Type ofService. However, the granularity of

    representation can be an issue inmapping across sites.

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    Other Evaluations

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    Other Evaluations

    Dugas M, Thun S, Frankewitsch T, Heitmann KU.LOINC codes for hospital information systems documentsJ Am Med Inform Assoc. 2009 May-Jun;16(3):400-3.

    PMID: 19261942.

    Hyrinen K, Mykknen J.

    Mapping the Finnish National EHR to the LOINC.Stud Health Technol Inform. 2011;165:161-6.

    PMID: 21685603.

    Reeves RM, FitzHenry F, Brown SH, et al.

    Who said it? Establishing professional attribution among authorsof Veterans' Electronic Health Records.

    AMIA Annu Symp Proc. 2012;2012:753-62. Epub 2012 Nov 3.PMID: 23304349.

    http://www.ncbi.nlm.nih.gov/pubmed/23304349http://www.ncbi.nlm.nih.gov/pubmed/21685603http://www.ncbi.nlm.nih.gov/pubmed/19261942
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    Still ongoing development

    photo via shutterrunner

    http://www.flickr.com/photos/shutterrunner/5266319924
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    The FutureGreat Scott!

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    Future Directions

    More v1 and v2 axis value harmonizationIdentifiers for the axis values

    Axis definitions

    Computable hierarchyExtension to other Kind of Documents

    Empiric analysis of document contents

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