CHEMILINES CHOOSE EVAPORATIVE COOLING TO ACHIEVE MHRA COMPLIANT CONDITIONS IN THEIR PHAMACEUTICAL WAREHOUSE

2015 Pharmaceutical Warehouse Evaporative Cooling

sales@ecocooling.org +44 (0)1284 810586 @EcoCooling1 www.ecocooling.org

Founded 18 years ago, Chemilines is a parallel importer of pharmaceutical products with the NHS as its ma-jor customer. In March 2008 the company opened a new 90,000 sq ft repackaging and warehouse facility in Wembley.

A key objective was to ensure that the warehouse complied with temperature controlled storage conditions as regulated by The Medicines and Healthcare Products Regulatory Agency (MHRA). Please see the next page for a breakdown of the MHRA storage guideleines

Merck Sante, based in the French city of Orleans, manufactures and distributes pharmaceutical products. Their main warehouse is required to operate under the conditions of ‘controlled room temperature’ which for their range of products is less than 25°C .

MERCK USE ECOCOOLING TO COOL THEIR PHARMACEUTICAL WAREHOUSE

Eighteen down discharge EcoCooling ECP16000 evaporative coolers were installed feeding high level plenum chambers. These positively pressurise the warehouse and air is extracted using automatic vents. The coolers are all linked to a common control panel.

Temperature is monitored at three levels in the ware-house and the coolers controlled accordingly. A humidistat ensures that the internal humidity does not exceed 85%.

The principle of mean kinetic temperature (MKT) can be applied to pharmaceutical storage using the Arrhenius Equation.

The graph to the right shows that on a 40°C day the ambient MKT is 33°C. The output of an evapora-tive cooler in these conditions gives an MKT of 25°C which meets the storage criteria for this range of pharmaceutical products as defined by the MHRA guidelines.

All coolers are linked to the fire alarm system for automatic shutdown.

sales@ecocooling.org +44 (0)1284 810586 @EcoCooling1 www.ecocooling.org

2015 Pharmaceutical Warehouse Evaporative Cooling

EcoCooling evaporative cooling was applied as part of a complete warehouse temperature control scheme. The existing heating system was incorporated into an integrated approach to heating, cooling and de-stratifi-cation. A central controller also provides data capture with remote access and automated alarm communica-tion.

Full monitoring and data logging was provided together with SMS messaging of alarm conditions.

The current principles being applied to meet the MHRA controlled temperature guidelines are:

• The system shall be designed to maintain the warehouse under 25°C during normal UK weather conditions.

• In exceptional conditions the 7 day mean kinetic temperature shall not exceed 25°C.

• There shall be no ‘excursions’ over 30°C.

Chemilines Warehouse Temperature Graph

Paul Gilmour, Scotchem Ltd -“We had 1 EcoCooler installed at end of 2006 to service 2 small units where prescription medicines are stored which deteriorate if the temperature goes above 25 degrees. We added 2 more units last year and we are very happy with the product as it is a very good product for the price, achieves good results, and is not as bulky as an air handling system”

For more information and case studies please visit the EcoCooling website www.ecocooling.org. Presenta-tions and introduction videos are also avaliable on the EcoCooling YouTube channel.

HOW MUCH COULD YOU SAVE USING AN ECOCOOLING ECP SYSTEM?

A building requiring 30kW peak load and 20kW minimum load. Cooling employed from April to October from 6am to 6pm, 5 days per week, in London, with electricity cost 8p/kWhr and water cost £1.20/m3.

Running Costs - Annual Evaporative Cooling Air Conditioning Calculated SavingCOP/EER 66.4 3.4 Electricity (KWhr) 1,515 14,770 13,255Electricity Cost (£) £121 £1,182 £1,060Water Usage (m3) 45.5 0.0 45.5Water Cost (m3) £54.65 £0.00 - £54.65Total Cost £176 £1,182 £1,006

TESTIMONIAL

TYPICAL INSTALLATION SCHEME

The below installation scheme incorporates cooling, heating and destratification. The system includes hot air recirculation which means that a consistant supply temperature can be achieved all year round. The ECP range of coolers are also avaible in side and top discharge models to allow for variances in installation techniques (i.e. if they cannot be placed on the roof). For more details on possible installation techniques please contact EcoCooling directly.

sales@ecocooling.org +44 (0)1284 810586 @EcoCooling1 www.ecocooling.org

Cold external air

EcoCooling ECP Wetbox

Recirculation Damper

EC Supply Fan

Hot Air

Cold Air

Attemperated Air

Recirculated Hot Air

ADDITIONAL FEATURES

CONTROLS

The system is controlled using slave PLCs and a central HMI touch screen for fully automatic control of heating and cooling in single spaces or zoned warehouses. The latest control systems can include network communications, data and event logging, secure remote access, optional email notifications and online MKT graphical analysis.

EU4 Pre-filter

EcoCooling systems use Electrically Commutated (EC) fans which are the most efficient available. Further efficiency is gained by speed control. Operating the EcoCooling system at half speed reduces the fan energy use by over 85%. This permits extremely high cooling efficiencies at part population of data centres or server rooms.

The EcoCooling evaporative cooler maintains hygienic operation and fully complies with all legionella control regulations by applying the following principles: Avoidance of droplets; Low water operating temperature; Avoidance of stagnant water; Avoidance of corrosion and scaling; Regular maintenance.

Supply Damper

Attemperated Supply Air

8-Way Plenum

2015 Pharmaceutical Warehouse Evaporative Cooling