21-cranial nerve vii & viii€¦ · facial nerve (vii) mixed cranial nerve motor modalities...

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Cranial Nerve VII & VIII

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Page 1: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Cranial Nerve VII & VIII

Page 2: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Lecture Objectives

• Follow up the course of facial nerve from its point of central connections, exit and down to its target areas.

• Follow up the central connections of the facial nerve. • Discuss the various modalities of its fibers.• Review your knowledge of its target organs.• Follow the course of the VIII nerve down to its point of entry to the brain.

• Follow up the central connections of the VIII nerve. 

Page 3: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Facial Nerve (VII)Mixed cranial nerve

Motor Modalities

• Motor fibers (SVE) originate from the pons and innervate facial, scalp muscles

• Parasympathetic innervation (GVE) (via the pterygopalatine and submandibular ganglia) to various glands in the head

Major motor functions are regulating muscles of facial expression and secretion of saliva and tears

Page 4: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Facial Nerve (VII)

Sensory Modalities• Sensory fibers (SVA) from the taste buds of the anterior ⅔ of the tongue

• Sensory fibers (GVA) from soft palate

• Sensory fibers (GSA) from external earAll sensory fibers go to the geniculate ganglion (in facial canal)

Page 5: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Facial Nerve Nuclei• Main motor nucleus (SVE)

• Location• Connection

• Cortex*• Upper muscles – both sides• Lower muscles – contralateral 

innervation*upper motor neuron lesion would affect lower muscles only

• Fibers course• Colliculus facialis

Page 6: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Facial Nerve Nuclei

• Parasympathetic nuclei (GVE)• Superior salivatory

• Connections • Hypothalamus 

• Lacrimal• Connections 

• Hypothalamus • Sensory nuclei of V

• Corneal irritation

Page 7: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Facial Nerve: Sensory Nucleus

• 1st order neuron – geniculate ganglion

• 2nd order neuron –Nucleus of the tractus solitarius (SVA, GVA)• Taste and sensation from palate• Location• Axons cross midline

• 3rd order neuron – PVM of thalamus• Axons → internal capsule → corona radiata → cortex (postcentral gyrus)

Page 8: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Facial Nerve (VII): Course

• Facial nerve (motor root (SVE) & nervus intermedius(GVE,SVA,GVA,GSA))

• Pons (cerebellopontine angle)

• Internal acuastic meatus

• Facial canal

• Stylomastoid foramen

Page 9: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Facial Nerve (VII): Branches• Nerve to the stapidius muscle (SVE)

• Posterior auricular n. (SVE)• Stylohyoid & posterior belly of digastric

• Five terminal branches (SVE)

Page 10: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Facial Nerve (VII): Branches

• Greater petrosal nerve (GVE, GVA)↔ hiatus of the facial canal ↔ pterygoid canal ↔ pterygpalatine ganglion

Page 11: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Facial Nerve (VII): Branches

• Chorda tympani n. (GVE, SVA,GVA) ↔ canal in the tympanic cavity ↔ canal in the petrotympanic fissure ↔ foramen at the spine of sphenoid ↔ lingual nerve (V3)

Page 12: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic
Page 13: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Facial Nerve (VII): Lesion

• Bell’s palsy: paralysis of facial expression mm. • Unable to show teeth and close eye

• Loss of corneal reflex (efferent limb)

• Loss of taste from the anterior ⅔ of tongue (corda tympani)• Unable to distinguish taste sensations (sweet, bitter, sour & salt)

• Decrease salivation (corda tympani)

Page 14: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

UMN Vs LMN Lesions of Facial Nerve

Page 15: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Vestibulocochlear Nerve (VIII)• Formerly called the acoustic or auditory nerve

• Brainstem (between pons & medulla) → Internal acoustic meatus

• Mainly a sensory nerve

• Consists of two branches:

Cochlear branch• Associated with hearing• Receptors in the spiral organ in the cochlea • The cell bodies in the spiral ganglion• Axons travel to nuclei in the medulla• if damaged deafness or tinnitus (ringing) is 

produced

Page 16: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Auditory Nuclei/Pathway

• 1st order neuron – spiral ganglion

• 2nd order neurons• Cochlear nuclei

• Anterior & posterior• Location• Relations – inferior cerebellar 

peduncles

• Axons cross and uncross midline

Page 17: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Auditory Nuclei/Pathway• 3rd order neurons 

• Posterior nucleus of trapezoid body & superior olivary nucleus

• Axons – lateral lemniscus

• 4th order neurons• Inferior colliculus• Medial geniculate body (5th) → internal capsule → auditory cortex (superior temporal gyrus)

Page 18: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

Vestibulocochlear Nerve (VIII)

Vestibular branch• Associated with equilibrium• Receptors in the semicircular canals; saccule, and utricle 

• The cell bodies in vestibular ganglion

• Axons travel to nuclei in the thalamus; some fibers also travel to the cerebellum

• Lesion results in disequilibrium, vertigo, nystagmus, ataxia

Page 19: 21-Cranial Nerve VII & VIII€¦ · Facial Nerve (VII) Mixed cranial nerve Motor Modalities •Motor fibers (SVE) originate from the ponsand innervate facial, scalp muscles •Parasympathetic

The Vestibular Nuclei/Pathway

• Location – 4th ventricle• Vestibular nuclei (2nd order neurons)• Lateral → vistibulospinal tract• Superior• Medial• Inferior

• Inputs from cerebellum• Axons To spinal cordTo eye muscles nerves (III, IV, VI)To thalamus (VP) → vestibular area in cerebral cortex (postcentral gyrus)