2:45-3:15 pm on thursday (28 th november). meet with quality assurance external reviewers for the...

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2:45-3:15 PM on Thursday (28 th November). Meet with quality assurance external reviewers for the school of professional studies. Nutrition transfer student volunteers please email me and Marcy MacKinnon [email protected]

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2:45-3:15 PM on Thursday (28th November).

Meet with quality assurance external reviewersfor the school of professional studies.

Nutrition transfer student volunteers please email me and Marcy [email protected]

indicating whether you are year 1 or 2 andwith you willingness to do so- your help is verymuch required and appreciated. Thank you!!!

Winter 2013

Final exam 15 questions-short answer-point form covering whole term5 Q on diabetes and atherosclerosis10 Q on blood pressure, stroke, and kidney disease-10 points each- 3 hours-no choice on questions

The

Lecture 12- 26 November 2013

KIDNEY DISEASE

Outline of todays talk

I. Pathology  

 

II. Socioeconomic factors contributing to ESRD 

III. Elementary nutritional approaches to be taken to avoid and treat ESRD including foods available to those at risk 

 

IV. First Nations and other Cape Breton individuals at risk

 

V. How is nutritional assessment made for kidney disease? 

VI. How would one assess from a nutritional perspective the socioeconomics, pathology and success of

nutritional interventions relative to ESRD?  

Kidney DiseaseI. Pathology

Types of Kidney Disease

glomerular diseasenephrotic syndromenephritic syndrome

Kidney DiseaseI. Pathology

Types of Kidney Disease

glomerular diseasenephrotic syndrome

-loss of glomerlular barrier to

proteinnephritic syndrome

-inflammation of capillary loops of glomerulus

Kidney DiseaseI. Pathology

Types of Kidney Disease

Diseases of the tubules and interstitiumacute renal failurepyelonephritisnephrolithiasis

Focus on end stage renal disease

Kidney DiseaseI. Pathology

Types of ESRD

Diseases of the tubules and interstitiumacute renal failure

sudden reduction in glomerular filtration rate-pre-, intrinsic and post- renal flow drops

pyelonephritisnephrolithiasis

Kidney DiseaseI. Pathology

Diseases of the tubules and interstitiumpyelonephritis-urinary tract infection

nephrolithiasis-kidney stones

End stage renal disease (ESRD)I. Pathology

End-stage renal disease

inability to produce waste products, maintain fluid, and electrolyte balance and produce hormones

diabetes

ESRD

I. Pathology

End-stage renal disease-associations

diabetes (types I and II)

glomerulonephritis

hypertension

End stage renal diseaseI. PathologyWhat are the risk factors?End-stage renal disease

Obesity and all its sequelae leading to metabolic syndrome

genetics and dietary risk factors for type I diabetes

End stage renal disease

I. PathologyWhat are the risk factors?

Glomerulonephritisinfection- immune

system requires adequate balanced

nutrition

End stage renal diseaseI. PathologyWhat are the risk factors?

Hypertension-damages tissues

-all causes of hypertension

Socioeconomic factorsFood and hence nutritional choices depend on:

Personal preference-protective factors(preventative)-absence is a risk factor

type I and type II diabetes-review

infection-review

hypertension-review

Socioeconomic factors

Food and hence nutritional choices depend on:

Habittype I and type II diabetes-review

infection-review

hypertension-review

Food and hence nutritional choices depend on:Ethnic heritage or tradition

type I and type II diabetes-review

infection-review

hypertension-review

Social interactionrelate social interaction to ethnic heritage or tradition

Food and hence nutritional choices depend on:

Availability of food

• type I and type II diabetes-review• infection-review• hypertension-review

Convenience of food

• type I and type II diabetes-review• infection-review• hypertension-review

Food and hence nutritional choices depend on:

Economy of food

• type I and type II diabetes-review

• infection-review

• hypertension-review

Food and hence nutritional choices depend on:

Positive and negative associations

• type I and type II diabetes-review

• infection-review

• hypertension-review

Food and hence nutritional choices depend on:

Emotional conflict

• type I and type II diabetes-review

• infection-review

• hypertension-review

Food and hence nutritional choices depend on:

Values-how does this apply to:

• type I and type II diabetes-review

• infection-review

• hypertension-review

Food and hence nutritional choices depend on:

Body image

• type I and type II diabetes-review

• infection-review

• hypertension-review

Food and hence nutritional choices depend on:

Advertising-who is responsible for encouraging or not encouraging

• type I and type II diabetes-review

• infection-review

• hypertension-review

BREAK

More on socioeconomic factors

Prestige-occupational-

lower the occupation the greater the risk of ESRD-why?

low occupational fathers tend to have low or lower occupational kids

could be a number of generations before population end-stage renal disease risk is reduced

More on socioeconomic factors

Prestige-occupational-

higher the occupation the less the risk of ESRD-why?

high occupational fathers tend to have high or higher occupational kids

could be a number of generations before population ESRD risk is increased among descendants of initial high

occupational fathers

More on socioeconomic factors

Prestige

-societal perceptions-dictate ability of people to change their social rankings

-education-eg university professors and astronauts have a lot of sophisticated

education and they are rated highly-however this is no guarantee that there is no risk of ESRD

More on socioeconomic factors

Power-based on societal perceptions to some extent

Income-also based on societal perceptions of the importance of the job to society

More on socioeconomic factors

Wealth-based on education-lower classes tend to be less well educated and therefore less able to take advantage of the societal perceptions that improve one’s socioeconomic status including wealth

Education- lower classes tend to be less well educated and therefore less able to take advantage of the societal perceptions that improve one’s socioeconomic status including the benefits arising from that education

More on socioeconomic factors

Social stratification

-ancestry-diabetes, infection, blood pressure

-gender-diabetes, infection, blood pressure

-race- diabetes, infection, blood pressure

-ethnicity- diabetes, infection, blood pressure

More on socioeconomic factors

Social stratification-mobility-diabetes, infection, blood pressure

-mental and physical activity-mental patients-may be marginalised by society-what impact does this have onthe risk of ESRD?

physical activity

More on socioeconomic factors

Social stratification

physical activity-ESRD risk lowered by chronic aerobic activity-caution with elevated blood pressure- blood pressure increases during aerobic exercise

- benefit with exercise comes after blood pressure is lowered in rest and during exercise- this is a training effect

More on socioeconomic factors

Social stratification

physical activity-impact on type I and II diabetes

-impact on infection

More on socioeconomic factors

Class-uppers-lower uppers-upper middles-average middles-working class-lower class

How might each of these classes have an impact risk or presence of ESRD?

More on socioeconomic factors

Global economy-globalisation- impact on:• type I and type II diabetes-review• infection-review• hypertension-review

Government-nutrition policies affect risk of ESRD-how?

• type I and type II diabetes-review• infection-review• hypertension-review

More on socioeconomic factors

Business-promotion of globalisation-why would business promote globalisation?

Psychology-susceptibility to business tactics such as?- impact on the risk of ESRD?

History-one’s habits and childhood socioeconomic status

Elementary nutritional biochemistry of nutritional approaches that use foods available to those at risk

Planning a healthy diet 

To do this bear in mindAdequacy

BalanceEnergy controlNutrient densityModerationVariety

Elementary nutritional biochemistry of nutritional approaches that use foods available to those at risk

Prevention-eat foods in accordance with:

• type I and type II diabetes-review• infection-review• hypertension-review

Elementary nutritional biochemistry of nutritional approaches that use foods available to those at risk

Post-onset-eat foods in accordance with

• type I and type II diabetes-review• infection-review• hypertension-review

BREAK

IV. First nations and other Cape Breton individuals at risk.

Aboriginals

Retired

Unemployed

Genetics

Others?

How is nutritional assessment made for ESRD-prevention and cure?Nutrient intake analysis

• type I and type II diabetes-review• infection-review• hypertension-review

How is nutritional assessment made for ESRD-prevention and cure?

Nutrient intake analysis

FLUID-WHY?SODIUM-WHY?POTASSIUM-WHY?CHLORIDE-WHY?GLUCOSE-WHY?CALCIUM-WHY?PHOSPHOROUS-WHY?

How is nutritional assessment made for ESRD- prevention and cure?

Daily food record/Diary

what are potential problems with this approach regarding ESRD?

How is nutritional assessment made for ESRD-prevention and cure?

Retrospective data

-24 hour recall

-food frequency questionnaire

both 24 hour recall and are used to cross check one another-how would this apply to ESRD

How is nutritional assessment made for ESRD-prevention and cure?

Anthropometry-

• type I and type II diabetes-review• infection-review• hypertension-review

How is nutritional assessment made for ESRD--prevention and cure?

Nutrition focussed physical exam:

• type I and type II diabetes-review• infection-review• hypertension-review

How is nutritional assessment made for ESRD-prevention and cure?

Skin testing-applicable

• type I -review• infection-applicable?• hypertension-applicable?

How is nutritional assessment made for ESRD-prevention and cure?

Biochemical analysis

• type I and type II diabetes-review• infection-review• hypertension-review

How is nutritional assessment made for ESRD--prevention and cure?

Biochemical analysis

FLUID-WHY?SODIUM-WHY?POTASSIUM-WHY?CHLORIDE-WHY?GLUCOSE-WHY?CALCIUM-WHY?PHOSPHOROUS-WHY?

How is nutritional assessment made for ESRD-prevention and cure?

CLASSIFYING MALNUTRITION

obesity is the main issue here

thin individuals are much less at risk than obese persons

VI. GROUP DISCUSSION-HOW WOULD ONE ASSESS FROM NUTRITIONAL PERSPECTIVE THE SOCIOECONOMICS, PATHOLOGY AND SUCCESS OF NUTRITIONAL INTERVENTIONS RELATIVE TO ESRD ?