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Improving Grant Funding AASIG - NYC October 5 ,2002 The NIH Stuart A. Binder-Macleod, PT, PhD University of Delaware Dept. of Physical Therapy

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Improving Grant FundingAASIG - NYCOctober 5 ,2002

The NIH

Stuart A. Binder-Macleod, PT, PhD

University of Delaware

Dept. of Physical Therapy

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The NIH

• Overview of the Review and Funding Process

• Funding Mechanisms for Research and Training

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Overview of the NIH

The NIH mission is to uncover new knowledge that will lead to better health for everyone. NIH works toward that mission by:

• conducting research in its own laboratories;• supporting the research of non-Federal scientists in

universities, medical schools, hospitals, and research institutions throughout the country and abroad;

• helping in the training of research investigators; and• fostering communication of medical information.

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Overview of the Grants Process

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Funding Opportunities

• Over $27,000,000,000 in funding for FY2003

• 85% for extramural funding

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Funding Opportunities

Training, Fellowships and Career Development Programs– Institutional Training Grants– Fellowships (F series) – Career Development Programs (K series)

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Funding Opportunities

Fellowships Programs• Individual Predoctoral National Research Service Awards For

M.D./PH.D. Fellowships

• Individual Predoctoral Fellowships for Minority Students (F31)

• Individual Predoctoral Fellowships for Students with Disabilities (F31)

• Individual Fellowships for Graduate Students in Neuro-, Behavioral, Addiction, and Communication Sciences (F31)

• Individual Postdoctoral Fellowships (F32)

• Senior Fellowships (F33)

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Funding OpportunitiesCareer Development Programs• K01 Mentored Research Scientist Development Award. Career

development in a new area of research.

• K02 Independent Scientist Award. Develop the career of the funded scientist. . .

• K08 Mentored Clinical Scientist Development Award. Development of the independent clinical research scientist.

• K22 Career Transition Award. Support to an individual postdoctoral fellow in transition to a faculty position.

• K23 Mentored Patient-Oriented Research Career Development Award. Development of the independent research scientist in the clinical arena.

• K24 Midcareer Investigator Award In Patient-Oriented Research. Development of clinical mentors conducting funded research.

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Funding Opportunities

Research Grants• Small Grants (R03) - provides limited financial support for new

biomedical and behavioral research projects.

2 years max. - $50K/year – non-renewable

• Academic Research Enhancement Award (R15) - support individual research projects in the biomedical and behavioral sciences conducted by faculty, and involving their undergraduate students, who are located in health professional schools and other academic components that have not been major recipients of NIH research grant funds.

3 years max. - $100K/year - non-renewable

http://grants.nih.gov/grants/funding/area.htm

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Funding Opportunities

Research Grants (continued)• Exploratory/developmental grants (R21) - used to

encourage the development of new research activities in categorical program areas. Most institutes do not accept unsolicited R21 applications. Complete descriptions of eligibility requirements, scope, and application procedures would be presented in a Request for Applications (RFA) utilizing this mechanism. 3 years max. - $150 K/year - non-renewable

• Research Project Grant (R01) - grants are awarded to institutions on behalf of a principal investigator to facilitate pursuit of a scientific focus or objective in the area of the investigator's interest and competence. 5 years max. - > $500K/year must contact institute staff - renewable

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Overview of NIH funding

Comprised of 27 separate components, mainly Institutes and Centers.

From a total budget of $300 in 1887, the NIH budget has grown to more than $27 billion in FY2003.

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Overview of NIH funding:Institutes and Centers

NHGRI - National Human Genome Research InstituteNHLBI - National Heart, Lung, and Blood InstituteNIA - National Institute on AgingNIAAA - National Institute on Alcohol Abuse and AlcoholismNIAID - National Institute of Allergy and Infectious DiseasesNIAMS - National Institute of Arthritis and Musculoskeletal and Skin Diseases

NICHD -National Institute of Child Health and Human DevelopmentNIDA - National Institute on Drug AbuseNIDCD - National Institute of Deafness and Other Communication DisordersNIDDK - National Institute of Diabetes and Digestive and Kidney DiseasesNIDCR - National Institute of Dental and Craniofacial ResearchNIEHS - National Institute of Environmental Health SciencesNIGMS - National Institute of General Medical SciencesNIMH - National Institute of Mental HealthNINDS - National Institute of Neurological Disorders and Stroke NINR - National Institute for Nursing Research

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Overview of the Grants Process

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Overview of the Review Process Research Grant Individual National Research Service (Fellowship) Award* Research Career Development Award

CSR Study Section

Program Project Institutional National

Research Service (Training) Award

RFAs (R01, R21)

Institute SRG

CSR

* Does not require Council review.

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Overview of the Review ProcessIRGs Within CSR

AARR  Behavioral and Biobehavioral Processes

BCS Biochemical Sciences

BPC Biophysical and Chemical Sciences

BDCN Brain Disorders and Clinical Neuroscience

CVS Cardiovascular Sciences

CDF Cell Development and Function

ENR Endocrinology and Reproductive Sciences

GNS Genetic Sciences

IMM Immunological Sciences

IDM Infectious Diseases and Microbiology

IFCN Integrative, Functional, and Cognitive Neuroscience

MDCN Molecular, Cellular, and Developmental Neuroscience

MSD Musculoskeletal and Dental Sciences

NMS Nutritional and Metabolic Sciences

ONC Oncological Sciences

PPS Pathophysiological Sciences

RPHB Risk, Prevention and Health Behavior

SNEM Social Sciences, Nursing, Epidemiology, and Methods

SRB Surgery, Radiology and Bioengineering

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Overview of the Review Process Study Sections within the MSD IRG:

General Medicine A-1 Study Section [GMA-1]General Medicine B Study Section [GMB]Geriatrics & Rehabilitation Medicine Study Section [GRM]Oral Biology & Medicine-1 Study Section [OBM-1]Oral Biology & Medicine-2 Study Section [OBM-2] Orthopedics & Musculoskeletal Study Section [ORTH]Urology Special Emphasis Panel [UROL SEP] Chronic Fatigue Syndrome/ Fibromyalgia Syndrome Special Emphasis Panel[CFS SEP]Bioengineering Research Partnerships/Grants SEP Special Emphasis Panel[SSS-M]

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Overview of Review Process• Critique

– Significance– Approach– Innovation– Investigator– Environment

• Does the scientific environment in which the work will be done contribute to the probability of success?

• Do the proposed experiments take advantage of unique features of the scientific environment or employ useful collaborative arrangements?

• Is there evidence of institutional support?

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Overview of the Grants Process

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The NIH

Questions / Comments / Ideas?