3.1 genes - bioninjabioninja.com.au/worksheets/topic 3.1 worksheet (answers).pdf · 3.1 genes genes...

2
3.1 Genes Genes Define the following terms Gene: ……………………………………………………………………………………………………………………………………………... Locus: ……………………………………………………………………………………………………………………………………………... Allele: ……………………………………………………………………………………………………………………………………………... Label the parts of the following chromosome 1. ………………………………………………………… 2. ………………………………………………………… 3. ………………………………………………………… 4. ………………………………………………………… Complete the following table comparing the genetic composition of various organisms Genome Size Diploid Number Number of Genes T2 Phage (virus) Not applicable 280 E. coli (bacteria) Not applicable O. sativa (rice) 470 Mb P. japonica (canopy plant) 40 Unknown D. melanogaster (fruit fly) 8 P. equorum (round worm) 185 Mb 14,000 C. familiaris (dog) 2,900 Mb 20,000 P. troglodytes (chimp) 3,300 Mb H. sapiens (human) 1 3 2 4

Upload: others

Post on 23-Jul-2020

20 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: 3.1 Genes - BioNinjabioninja.com.au/worksheets/topic 3.1 worksheet (answers).pdf · 3.1 Genes Genes Define the following terms ... The totality of genes in a cell, organism or organelle

3.1 Genes

Genes

Definethefollowingterms

Gene: ……………………………………………………………………………………………………………………………………………...

Locus:……………………………………………………………………………………………………………………………………………...

Allele:……………………………………………………………………………………………………………………………………………...

Labelthepartsofthefollowingchromosome

1. …………………………………………………………

2. …………………………………………………………

3. …………………………………………………………

4. …………………………………………………………

Completethefollowingtablecomparingthegeneticcompositionofvariousorganisms

GenomeSize

DiploidNumber

NumberofGenes

T2Phage(virus)

Notapplicable

280

E.coli(bacteria)

Notapplicable

O.sativa(rice)

470Mb

P.japonica(canopyplant)

40

Unknown

D.melanogaster(fruitfly)

8

P.equorum(roundworm)

185Mb

14,000

C.familiaris(dog)

2,900Mb

20,000

P.troglodytes(chimp)

3,300Mb

H.sapiens(human)

1 3

2 4

Brent Cornell
A section of DNA that codes for a particular characteristic (via the production of a specific protein)The specific location of a gene on a particular chromosomeAn alternate form of a gene�
Brent Cornell
p arm (shorter)centromereq arm (longer)telomere�
Brent Cornell
78
Brent Cornell
48
Brent Cornell
46
Brent Cornell
4
Brent Cornell
24
Brent Cornell
3,300 Mb
Brent Cornell
150,000 Mb
Brent Cornell
130 Mb
Brent Cornell
4.6 Mb
Brent Cornell
0.17 Mb
Brent Cornell
~4,200
Brent Cornell
~38,000
Brent Cornell
~13,000
Brent Cornell
~22,000
Brent Cornell
~21,000
Page 2: 3.1 Genes - BioNinjabioninja.com.au/worksheets/topic 3.1 worksheet (answers).pdf · 3.1 Genes Genes Define the following terms ... The totality of genes in a cell, organism or organelle

Definegenome

…………………………………………………………………………………………………………………………………………………..........

ListthreepotentialapplicationsofthecompletedHumanGenomeProject

1. …………………………………………………………………………………………………………………………………………………...

2. …………………………………………………………………………………………………………………………………………………...

3. …………………………………………………………………………………………………………………………………………………...

Mutations

Identifythreetypesofmutagens(includinganexampleofeach)

1. …………………………………………………………………………………………………………………………………………………...

2. …………………………………………………………………………………………………………………………………………………...

3. …………………………………………………………………………………………………………………………………………………...

Distinguishbetweensomaticandgermlinemutations

…………………………………………………………………………………………………………………………………………………..........

…………………………………………………………………………………………………………………………………………………..........

…………………………………………………………………………………………………………………………………………………..........

Explaintheconsequencesofabasesubstitutionmutationinthedevelopmentofsicklecellanaemia

………………………………………………………………………………………………………………

………………………………………………………………………………………………………………

………………………………………………………………………………………………………………

………………………………………………………………………………………………………………

………………………………………………………………………………………………………………

………………………………………………………………………………………………………………

………………………………………………………………………………………………………………

………………………………………………………………………………………………………………

………………………………………………………………………………………………………………

Brent Cornell
The totality of genes in a cell, organism or organelle
Brent Cornell
Screening for known genetic conditionsDiscovering new drug treatments and medications (e.g. phamacogenomics)Establishing ancestral lineages�
Brent Cornell
Physical (e.g. radiation)Chemical (e.g. tobacco and other carcinogens)Biological (certain viruses)�
Brent Cornell
Somatic mutations affect body cells and cannot be inherited by offspring (mutation restricted to affected tissue)Germline mutations affect sex cells and will be passed on to offspring (will affect all cells in offspring)�
Brent Cornell
• Mutations changes GAG to GUG on the mRNA transcript (this is a change of CTC to CAC on the antisense strand)• Mutation affects the 6th codon of the haemoglobin beta chain gene• The mutation change the amino acid from Glutamic acid to Valine (Glu to Val)• This causes the haemoglobin to form insoluble strands (and clump together)• The red blood cells adopt a characteristic sickle cell shape• The sickle cells break down, leading to anaemia and reduced oxygen transport• The sickle cell mutation demonstrates co-dominance• The trait shows heterozygous advantage (resistance to malaria) �