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The Hispanic Organization of Toxicologists (HOT) is a Special Interest Group of the Society of Toxicology ISSUE February-March 2015 33 Toxenlaces From the President Dear Colleagues and Friends, This is the last issue of Toxenlaces before the annual SOT meeting in San Diego. The HOT Executive Committee (EC) has been meeting monthly, and we are now in the final stages of planning for the HOT activities at the meeting. There are a number of HOT-related events that you should be aware of, which I hope you will attend. HOT posters. A sub-team of the EC is putting the final touches on the HOT poster that will be displayed and attended by HOT officers in the global gallery in the Exhibit Hall at the Convention Center from 11:45 AM - 12:15 PM on Monday, March 23 rd . Please stop by to see the poster and meet the officers. HOT in the SOT Pavilion. HOT will have a designated area in the SOT Pavilion. Please come and meet the officers and other HOT members who spend time at the Pavilion. If you have questions about HOT or have ideas about how HOT can better represent the Hispanic and Latino community in SOT, please stop by. We want to hear from you! HOT Mentoring Event. For students and trainees, be sure to attend this event that will take place on Tuesday, March 24 th from 7:00 AM - 8:00 AM in Room 2 of the Convention Center. Come and have a light continental breakfast and hear about ways to improve your CV, job hunting strategies, etc. In addition to presentations, there will be roundtables in which students will be able to interact directly with mentors who work in various employment sectors, including industry, academia and government. Global Hot Topics Event. While this is not officially an HOT event, I strongly encourage HOT members to attend this event sponsored by the SIG Collaboration Group and entitled Global Drug Development and Natural Products: End of an Era or an Endless Frontier? The event will take place on Wednesday, March 25 th at 7 AM in Room 2 of the Convention Center. Professor John Vederas from the University of Alberta and Dr. Jon Mirsalis from SRI International will tell us about natural products, their role in human health and their potential safety issues. A light continental breakfast will be served. I am happy to organize this event along with colleagues from the other SIGs (WIT, ASIO, TAO, AACT, and KTAA). HOT Sponsors P.8 HOT Executive Board P.9 Announcements P.11 HOT Officers Contact Linval DePass, Ph.D., DABT President [email protected] Minerva Mercado-Feliciano, Ph.D., DABT Vice President [email protected] Elena Hernández-Ramón, M.D., Ph.D. Vice President elected [email protected] Verónica Ramírez-Alcántara, Ph.D Secretary [email protected] Ranulfo Lemus Olalde, Sc.D. DABT Treasurer [email protected] Betzabet Quintanilla, Ph.D. Councilor [email protected] Azita Cuevas, MPH, Ph.D. Councilor [email protected] Silvia B. Moraes Barros, Ph.D. Councilor [email protected] Maria E. Gonsebatt, Ph.D. Councilor to Sister Organizations [email protected] Teresa de Jesús Palacios, Ph.D. Postdoctoral Representative [email protected] Federico L. Sinche, M.Sc. Graduate Student Representative [email protected] Betina Lew, Ph.D. Past President [email protected] From the President P.1 HOT Awards 2015 P.2 Distinguished Toxicologist P.5 HOT Member Presentations P.6 HOT Sister Organizations P.8

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  • The Hispanic Organization of Toxicologists (HOT) is a Special Interest Group of the Society of Toxicology

    ISSUE

    February-March

    2015

    33 Toxenlaces

    From the President Dear Colleagues and Friends,

    This is the last issue of Toxenlaces before the annual SOT meeting in San Diego. The HOT Executive Committee (EC) has been meeting monthly, and we are now in the final stages of planning for the HOT activities at the meeting. There are a number of HOT-related events that you should be aware of, which I hope you will attend. HOT posters. A sub-team of the EC is putting the final touches on the HOT poster that will be displayed and attended by HOT officers in the global gallery in the Exhibit Hall at the Convention Center from 11:45 AM - 12:15 PM on Monday, March 23rd. Please stop by to see the poster and meet the officers.

    HOT in the SOT Pavilion. HOT will have a designated area in the SOT Pavilion. Please come and meet the officers and other HOT members who spend time at the Pavilion. If you have questions about HOT or have ideas about how HOT can better represent the Hispanic and Latino community in SOT, please stop by. We want to hear from you!

    HOT Mentoring Event. For students and trainees, be sure to attend this event that will take place on Tuesday, March 24th from 7:00 AM - 8:00 AM in Room 2 of the Convention Center. Come and have a light continental breakfast and hear about ways to improve your CV, job hunting strategies, etc. In addition to presentations, there will be roundtables in which students will be able to interact directly with mentors who work in various employment sectors, including industry, academia and government.

    Global Hot Topics Event. While this is not officially an HOT event, I strongly encourage HOT members to attend this event sponsored by the SIG Collaboration Group and entitled Global Drug Development and Natural Products: End of an Era or an Endless Frontier? The event will take place on Wednesday, March 25th at 7 AM in Room 2 of the Convention Center. Professor John Vederas from the University of Alberta and Dr. Jon Mirsalis from SRI International will tell us about natural products, their role in human health and their potential safety issues. A light continental breakfast will be served. I am happy to organize this event along with colleagues from the other SIGs (WIT, ASIO, TAO, AACT, and KTAA).

    HOT Sponsors P.8 HOT Executive Board P.9

    Announcements P.11 HOT Officers Contact Linval DePass, Ph.D., DABT President [email protected] Minerva Mercado-Feliciano, Ph.D., DABT Vice President [email protected] Elena Hernández-Ramón, M.D., Ph.D. Vice President elected [email protected] Verónica Ramírez-Alcántara, Ph.D Secretary [email protected] Ranulfo Lemus Olalde, Sc.D. DABT Treasurer [email protected] Betzabet Quintanilla, Ph.D. Councilor [email protected] Azita Cuevas, MPH, Ph.D. Councilor [email protected] Silvia B. Moraes Barros, Ph.D. Councilor [email protected] Maria E. Gonsebatt, Ph.D. Councilor to Sister Organizations [email protected] Teresa de Jesús Palacios, Ph.D. Postdoctoral Representative [email protected] Federico L. Sinche, M.Sc. Graduate Student Representative [email protected] Betina Lew, Ph.D. Past President [email protected]

    From the President P.1 HOT Awards 2015 P.2

    Distinguished Toxicologist P.5 HOT Member Presentations P.6

    HOT Sister Organizations P.8

    mailto:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]:[email protected]

  • 2

    Section

    HOT Awards 2015 By Azita Cuevas, M.S., M.P.H, Ph.D.

    HOT Awards Committee Chair, 2014-2015

    The Hispanic Organization of Toxicologists (HOT) has provided Travel Awards since 2005 to Hispanic/Latino students and postdoctoral trainees working in the area of toxicology research. The HOT travel award is offered to outstanding young scientists of Hispanic/Latino origin to help with the associated costs of presenting their research at and attending the SOT Annual Meeting. I am excited to report we had a record high of 20 applicants and the stellar quality of the candidate's research made for extremely stiff competition.

    This year applicants represented universities and research institutions from Mexico, Brazil and the United States. We received applications from 2 undergraduates, 2 master’s students, 13 graduate students and 3 postdoctoral fellows. All applications are considered equally, regardless if they come from a postdoc, graduate student or undergraduate. The letter of recommendation and the applicant's SOT- accepted abstracts are judged by a panel of senior HOT members, based on the quality of the following criteria: rational/scope, experimental procedures, results, conclusion, and how the research helps to the advance of the field of toxicology. Each judge independently provides a score for each of the above-mentioned criteria for each applicant. The Awards Committee Chair adds up the individual judges’ scores and the awards go to the applicants with the top total score.

    HOT Reception. The signature event of the meeting will be the HOT Reception, which will take place at Café Sevilla Restaurant, 353 Fifth Avenue, in the Gaslamp Quarter on Tuesday, March 24th from 6:30 PM to 9 PM. There will be a formal program that will include a keynote address by the first person selected as a Distinguished Toxicologist by HOT, Dr. Ofelia Olivero. Ofelia will tell us how one can start out dancing tango in the streets of Buenos Aires and end up as a member of the SOT Council. There will be Student and Post-doc Travel Awards, announcements from our Sister Organizations in Latin America, delicious Spanish food and drinks, and plenty of opportunities for networking and socializing. Those who purchase an HOT pin will get a free glass of sangria, which we may all need to relax after a long day of symposia, workshops and roundtables. Finally, the evening would not be complete without music and dancing to bachata, salsa, and merengue (or even a step or two of tango).

    While attending the meeting in San Diego, please take this opportunity to meet as many current and past HOT officers and members as possible. If you want to become more involved with HOT, this is a great opportunity to let us know that you would like to do more as a member of HOT. Positions on the HOT EC open up each year, and we are always looking for members who would like to help on a HOT committee. Please check the HOT website for more information about the HOT EC and committees, and come to the meeting prepared to let us know how HOT can grow and improve as a professional organization for Hispanic/Latino toxicologists. Feel free to contact me at [email protected] or any member of the EC with questions or suggestions you may have for HOT. I look forward to meeting you in beautiful San Diego. Linval DePass, Ph.D., DABT Building Bridges through Toxicology HOT President

    Continued on following page

    mailto:[email protected]

  • 3

    Continued on following page

    It is time the world knows about you!! We are looking for outstanding Hispanic trainees to be feature in Toxenlaces. If you are that trainee or if you want to nominate somebody, send your/her/his biography and picture René Viñas –Trillo (Toxenlaces Editor) at [email protected] for inclusion in upcoming issues.

    David Pamies Johns Hopkins University Postdoctoral Travel Award Sponsorship: MRI Global

    Pamella Tijerina NYU School of Medicine

    Graduate Student Travel Award Sponsorship: Celanese

    Tania Libertad Jocobo Estrada CINVESTAV-IPN, México

    Graduate Student Travel Award Sponsorship: PepsiCo

    Daniel Hernández Cortés CINVESTAV-IPN, México

    Graduate Student Travel Award Sponsorship: Battelle

    Andrea Anaya Sánchez & Abel Aburto Platas

    Universidad de las Américas, Puebla (UDLAP), México

    Undergraduate Student Travel Award Sponsorship: Ingenieros Lemus

    de Mexico

    After careful evaluation the 2015 HOT Travel Award winners are:

    mailto:[email protected]

  • 4

    If you want to collaborate with short articles, news or notes related with Toxicology, send René Viñas –Trillo (Toxenlaces Editor) at [email protected] for inclusion in upcoming issues.

    Since these awards would not be possible without our sponsorship, HOT would like to recognize the generosity and dedication of the companies that sponsored this year's HOT Travel Awards. Additionally HOT would like to express its gratitude to the persons from each respected company who made such sponsorships possible:

    Ingenieros Lemus de Mexico

    Robert P. Casillas, Ph.D. Sponsoring: David Pamies

    Azita Cuevas, M.S., M.P.H, Ph.D. Sponsoring: Tania L. Jacobo Estrada

    Mari S. Stavanja, Ph.D. Sponsoring: Pamela Tijerina

    Ranulfo Lemus Olalde, Sc.D., DABT Sponsoring: Andrea Anaya Sanchez

    & Abel Aburto Platas

    Kevin Kerzee, Ph.D. Sponsoring: Daniel Hernádez Cortés

    Outstanding Postdoctoral

    Teresa Palacios Hernández, Ph.D.

    Johns Hopkins University

    Hispanic Organization of Toxicologist Officer Award 2015

    The HOT is also recognizing the dedication and service to HOT of their Officers. This year the HOT Officer Award is presented to its Postdoctoral Representative Teresa Palacios Hernandez, Ph.D.

    mailto:[email protected]

  • 5

    Hispanic Organization of Toxicologist Distinguished Toxicologist Award 2015

    The Distinguished Toxicologist Award will from this point forward be given each year to a toxicologist of Hispanic origin whose work exemplifies the mission of the HOT-SIG by contributing to the advancement of the field of toxicology. Furthermore, the recipient of this award will be considered based on their scientific and/or regulatory accomplishments as well as their community services.

    This year, we are very proud to announce the first Distinguished Toxicologist Award winner: Dr. Ofelia Olivero. Dr. Olivero is currently the Associate Director for Scientific Diversity of the Center for Cancer Training at the National Cancer Institute at NIH and is a Past President of HOT.

    Dr. Olivero was trained as a cytogeneticist in Argentina, and then did postdoctoral training at NIH in the National Cancer Institute. Her career continued in that organization, where she held positions of visiting associate, staff scientist, and senior staff scientist. She was able to combine her expertise in genetic toxicology with carcinogenesis. Her seminal observations on the transplacental carcinogenesis of agents used in AIDS therapy generated the field of molecular epidemiology of nucleoside analogs. She is presently applying molecular cytogenetic techniques to understand nucleoside analog induced carcinogenesis in an attempt to provide knowledge to generate safer drugs and treatments for HIV-1 patients. Dr. Olivero has generated a change in the culture of mentoring through her recent book on interdisciplinary mentoring and by delivering multiple talks and workshops on the topic. She is recognized nationally and internationally for her scientific profile and her mentoring knowledge. Additionally, she has shown a singular style of leadership based on consensus and inclusion and is currently president of the Environmental Mutagenesis and Genomics Society (formerly EMS), has been president of the Genetic Toxicology Association, and holds numerous positions in many scientific organizations. Her natural leadership, talent, and mentoring abilities together with her scientific creativity have empowered numerous young individuals to pursue careers in toxicology.

    Dr. Olivero will be receiving her Award during the HOT Reception on Tuesday 24th at Cafe Sevilla. Please join us to congratulate Dr. Olivero.

    Ofelia Ana Olivero, Ph. D., FATS Associate Director for

    Scientific Diversity National Cancer Institute, NIH

  • Some of our HOT members will be presenting the results of their research projects at this year’s annual meeting. We encourage you to visit their

    posters or oral presentations, meet them, get interest in their research and network! Check the list below to know the day and time of their presentations (poster sessions are by board number).

    ORAL PRESENTATION Tuesday March 24, 2015

    9:00 AM to 11:45 AM

    Session: Alternative Models to Study Classical Toxicants: A Mechanistic View. Title: 3D MODELS AND OMICS APPROACHES TO STUDY PATHWAYS OF DEVELOPMENTAL NEUROTOXICITY. Author: David Pamies.

    POSTER SESSION

    Exhibit Hall CC Monday March 23, 2015

    9:30 AM to 12:30 PM Session: Risk Assessment I #329: BAYESIAN EVIDENCE INTEGRATION OF QUANTITATIVE HIGH THROUGHPUT DATA. Authors: Druwe IL, Painter KL, Yost EE, Burgoon LD. Session: Nanotoxicology, General, Environmental, Metals #511: HEMOTOXICITY AND STABILITY OF LUMINESCENT NANOPARTICLES: IN VITRO AND IN VIVO EVALUATION. Authors: Minjares EL, González LS, Fernández GX, Arteaga CF, Palacios HT, Mendes RMA, Hernández GS, Hirata FG, Angulo MA.

    Session: Metals

    #550: DIETARY EXPOSURE ASSESSMENT OF THE TRACE ELEMENTS SE AND MN IN MEAT PRODUCTS CONSUMED IN THE UNITED STATES. Authors: Ortiz JGM, Santerre CR, O'Keefe M, Abdelmajid N, Domesle A, Quinn M, Fields R, Bennett P.

    Session: Biotransformation and Cytochrome P450

    #116: CELECOXIB REGULATES LIVER CYP AND ALTERS TESTOSTERONE HOMEOSTASIS IN A RAT HEPATOCARCINOGENESIS MODEL. Authors: Salcido-Neyoy, ME, Sierra-Santoyo A, López-González ML, Escobar-Wilches DC, Villa-Treviño S.

    Session: Nonpharmaceutical Safety Assessment

    #240: DIFFERENTIAL CYTOTOXICITY OF FREEZE-DRIED THALASSIA TESTUDINUM IN NORMAL AND TRANSFORMED HUMAN CELLS. Authors: Estrada-Muñiz E, Leyva-Bahena I, Rodeiro I, Vega L.

    1:00 PM to 4:30 PM Session: Pharmaceutical Safety: Small Molecule Case Studies #416: IMMUNOMODULATORY EFFECT OF 6-PENTADECYL SALICYLIC ACID IN AN IN VIVO MODEL OF TUMOROGENESIS. Authors: Rashida JN, Estrada-Muñiz E, Vega L.

    Session: Developmental Neurotoxicology-Stem Cells #449: PREDICTING NEUROTOXICITY IN HUMAN-DERIVED IPSC 3D MINI-BRAINS. Authors: Pamies D, Block K, Pardo-Villamizar C, Barreras P, Kumar A, Smirnova L, Harris G, Bressler J, Kyro K, Christian KM, Ce Zhang, Hartung T, Hogberg HT. Session: Ocular Toxicology - Safety Assessment Approaches for Product Development #458: CLINICAL PROGRESSION OF OCULAR INJURIES FROM ARSENICAL VESICANT LEWISITE EXPOSURE. Authors: Tewari-Singh N, Goswami DG, Nagvekar A, Sosna WA, Peters E, Tuttle RS, Culley T, Croutch CR, Casillas RP, Agarwal R. Session: Alternatives to Mammalian Models II—Skin, Eye, Liver #445: ANALYSIS OF GENE EXPRESSION CHANGES OF HEPG2, HEPARG, AND ICELL HEPATOCYTES ELICITED BY CHEMICAL EXPOSURE. Authors: Naciff JM, Shan Y, Wang X, Abrew ND, Adams R, Tiesman JP, Wetmore BA, Thomas RS, Settivari R, Carney E, Daston GP. Session: Genetic Toxicology I #534: ROLE OF HELICASES IN REMOVAL OF ZIDOVUDINE (AZT)-INDUCED GENOTOXICITY IN DNA-REPAIR DEFICIENT HUMAN CULTURED FIBROBLASTS. Authors: Momot D, Poirier MC, Olivero O.

    POSTER SESSION

    Exhibit Hall CC Tuesday March 24, 2015

    9:30 AM to 12:30 PM Session: Carcinogenesis I #249: GENE EXPRESSION CHANGES IN HUMAN ENDOMETRIAL CELLS EXPOSED TO THE TAMOXIFEN METABOLITE ENDOXIFEN. Authors: Hernandez Ramon EE, Divi K, Asaki E, Olivero OA, Poirier MC. Session: Neurotoxicology, Metals-Lead and Others

    #227:NEUROLOGICALEFFECTS OF GESTATIONAL ARSENIC EXPOSURE. Authors: Ramos-Chavez LA, Rendon-López CR, Zepeda A, Silva-Adaya D, Del Razo LM, Gonsebatt ME. Session: Juvenile Toxicity

    #341: EXPOSURE TO PARTICULATE MATTER INCREASES THE DNA METHYLATION OF REPAIR GENES IN URBAN CHILDREN. Authors: Alvarado-Cruz I, Sánchez-Guerra M, Hernández-Cadena L, De Vizcaya A, Solis-Heredia MJ, Mugica V, Byun HM, Baccarelli A, Quintanilla-Vega B.

    Session: Genetic Toxicology II

    #423: CYTOTOXICITY AND GENOTOXICITY ASSESSMENT OF SANDALWOOD ESSENTIAL OIL IN HUMAN BREAST CELL LINES MCF-7 AND MCF-10A. Authors: Ortiz C, Morales L, Sastre M, Haskins WE, Matta J.

    6

    HOT Member Presentations

  • 1:00 PM to 4:30 PM Session: Skin #147: VEGF EXPRESSION ON 3D SKIN EQUIVALENT PLAYS AN ACTIVE ROLE IN MAINTAINING EPITHELIAL INTEGRITY BY INDUCTING CAPILLARY-LIKE STRUCTURE AND KERATINOCYTE PROLIFERATION. Authors: Leme DM, Abe FR, Costa CRV, Trindade ES, Buchi DF, Oliveira DP. Session: Immunotoxicity II #253: METABOLITES OF ORGANOPHOSPHOROUS PESTICIDES (DIETHYLDITHIOPHOSPHATE) INDUCE CHANGES IN MACROPHAGES POLARIZATION IN A BREAST CANCER MODEL. Authors: Medina-Buelvas DM, Estrada-Muñiz E, Vega L Session: Reproductive Toxicology II

    #454: MODULATION OF NRF2 AND OGG1 EXPRESSION IN GERM TESTICULAR CELLS BY METHYL PARATHION EXPOSURE: AN EPIGENETIC MECHANISM. Authors: Hernández-Cortés D, Alvarado-Cruz I, Solís-Heredia MJ, Quintanilla-Vega B.

    #453: A NEW OXIDATIVE MECHANISM OF METHYL PARATHION REPRODUCTIVE TOXICITY: DISRUPTION OF THE BLOOD-TESTIS BARRIER. Authors: Tello-Mora P, Solís-Heredia MJ, Ortega

    Session: Nanotoxicology, CarbonBased Nanomaterials

    #125: SINGLE-WALLED CARBON NANOTUBES (SWCNTS) INDUCE VASODILATION IN ISOLATED RAT AORTIC RINGS. Authors: Ramirez-Lee MA, Gutiérrez-Hernández JM, Rosas-Hernandez H, Salazar-García S, Maldonado-Ortega DA, González FJ, Syed FA, Gonzalez C.

    POSTER SESSION Exhibit Hall CC

    Wednesday March 25, 2015

    9:30 AM to 12:30 PM

    Session: Nanotoxicology, In Vitro #561: SYNTHESIS, CHARACTERIZATION, AND ANTIMICROBIAL ACTIVITY OF DRUG-LOADED CALCIUM ALGINATE NANOCAPSULES: PERSPECTIVES ON THEIR POTENTIAL BIOMEDICAL USE. Authors: Anaya-Sanchez A, Aburto-Platas A, Mendez MA, Miranda MC, Cachau RE, Delgado-Jimenez JF, Palacios-Hernandez TD. Session: Risk Assessment III #437: A PROPOSED ADVERSE OUTCOME PATHWAY FOR URANIUM-INDUCED OSTEOTOXICITY. Authors: Arzuaga X, Gehlhaus M, Strong JB, Fritz J, Lee JS.

    1:00 PM to 4:30 PM

    Session: Epigenetics

    #517: FURAN INDUCES LONG-TERM PERSISTENT EPIGENETIC ALTERATIONS IN THE LIVERS OF FISHER 344 RATS. Authors: de Conti A, Kobets T, Tryndyak V, Han T, Fuscoe JC, Beland FA, Doerge DR, Pogribny IP.

    #536: GENETIC DAMAGE IS ASSOCIATED WITH THE DNA METHYLATION IN CORD BLOOD FROM A POPULATION HIGHLY EXPOSED TO AIR POLLUTANTS. Authors: Montes-Castro N, Alvarado-Cruz I, García-Aguilar I, Solís-Heredia MJ, Rangel-Calvillo M, López-Bayghen E, Quintanilla-Vega B.

    # 504: EXAMINING ENVIRONMENTAL EFFECTS ON THE EPIGENOME. Authors: Camacho J, Allard P, Kreik S, Lundby Z.

    Session: Kidney #563: EFFECT OF CADMIUM EXPOSURE DURING GESTATION OVER HIF-1 IN RAT FETAL KIDNEY. Authors: Jacobo-Estrada T, Cárdenas-González M, Parada-Cruz B, Barbier O.

    Session: Chemical and Biological Weapons

    #145: THIOREDOXIN CROSS-LINKING BY THE SULFUR MUSTARD ANALOG MECHLORETHAMINE (METHYLBIS(2-CHLOROETHYL)AMINE) IN LUNG EPITHELIAL CELLS. Authors: Jan Y, Heck DE, Casillas RP, Laskin DL, Laskin JD.

    #153: LEWISITE EXPOSURE CAUSES HISTOPATHOLOGICAL CHANGES RELATED TO INFLAMMATION, CELL DEATH, AND NEOVASCULARIZATION IN THE RABBIT OCULAR MODEL. Authors: Goswami DG, Tewari-Singh N, Kant R, Nagvekar A, Agarwal C, Croutch CR, Casillas RP, Ammar DA, Petrash J, Agarwal R.

    #156: CONNEXIN 43 ANTISENSE THERAPY USING A NITROGEN MUSTARD HAIRLESS MOUSE SKIN MODEL. Authors: Chang Y, Chang H, Hahn RA, Lee EE, Casillas RP, Gordon MK, Gerecke DR.

    #164: INFLAMMATORY CELL ACCUMULATION IN MOUSE SKIN FOLLOWING EXPOSURE TO SULFUR MUSTARD. Authors: Joseph LB, Composto GM, Kim S, Croutch CR, Casillas RP, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD, Heck DE.

    Session: Carcinogenesis II

    #140: NOVEL PHOSPHODIESTERASE 10 INHIBITOR WITH ANTITUMOR ACTIVITY IN AN ORTHOTOPIC MOUSE MODEL OF LUNG CANCER. Authors: Ramirez-Alcantara V, Schuler MA, Zhu B, Li N, Gurpinar E, Canzoneri J, Keeton A, Gary, Bernard R, Suzanne C, Lori G, Gregory G, William E, Chen X, Piazza GA.

    POSTER SESSION Exhibit Hall CC

    Thursday March 26, 2015

    8:30 AM to 12:00 PM

    Session: Late-Breaking Poster Session 5

    #515: NEURONAL TOXICITY DUE TO REACTIVE DOPAMINE METABOLITES AND FUNGICIDE EXPOSURE. Author: Vanle B, Doorn J.

    #557: 8-OXOGUANINE DNA GLYCOSYLASE-1 DNA REPAIR-SIGNALING INDUCES GENE EXPRESSION ASSOCIATED TO AIRWAY REMODELING. Authors: Aguilera-Aguirre L, Bacsi A, Wood TG, Brasier AR, Ameredes BT, Ba X, Boldogh, I.

    #542: CHARACTERIZATION OF THE ROLE OF CANNABINOID RECEPTORS ON DENDRITIC CELL ANTIGEN PRESENTING FUNCTION. Authors: Suarez-Martinez J, Crawford R, Norbert K.

    #524: OXIDATIVE STRESS AND PROINFLAMMATORY CYTOKINES GENE OVEREXPRESSION IN CORTICAL ASTROCYTES ACUTELY EXPOSED IN VITRO TO THE MONOMETHYLATED ARSENIC METABOLITE: Authors: Escudero-Lourdes C, Uresti-Rivera EE, Rojas-Barajas IJ, Torres-Ramos M, Cuevas E.

    7

    HOT Travel Award Winners 2015. For general information about SOT Annual Meeting program, visit: http://www.toxicology.org/AI/MEET/am2015/

  • AETOX – http://www.aetox.com

    Asociación Latinoamericana de Toxicología – http://www.alatox.org/qsomos/index.html

    Asociación Toxicológica Argentina – http://www.ataonline.org.ar

    Center of Environmental and Toxicological Research – University of Puerto Rico – http://cetr.rcm.upr.edu

    PLAGBOL – Salud, Agricultura y Medio Ambiente – http://plagbol.org.bo/noticias/enlaces

    Ritsq - http://www.ritsq.org

    Sociedade Brasileira de Toxicologia – http://www.sbtox.org.br/

    Sociedad Cubana de Toxicologia

    Sociedad Mexicana de Toxicolgía - http://www.somtox.com.mx/

    Society for Risk Analysis Latin America – http://www.srala.org/

    Toxicología Acuática Ambiental,

    Medicina Veterinaria-Universidad Nacional de Colombia - http://www.docentes.unal.edu.co/jfgonzalezma

    Universidad de Cartagena – http://reactivos.com

    HOT Sister Organizations

    2015 HOT Sponsors

    8

    If your Hispanic Organization is planning a Toxicology meeting or you are organizing a Toxicology event intended for a primarily Hispanic audience, and want to promote it, send an email to René Viñas –Trillo (Toxenlaces Editor) at [email protected] for more information for its inclusion in upcoming issues.

    If you are interested in being interviewed for the section When I Grow Up, please contact Azita Cuevas at [email protected]

    http://www.aetox.com/http://www.alatox.org/qsomos/index.htmlhttp://www.ataonline.org.ar/http://cetr.rcm.upr.edu/http://plagbol.org.bo/noticias/enlaceshttp://www.ritsq.org/http://www.sbtox.org.br/http://www.srala.org/http://www.docentes.unal.edu.co/jfgonzalezmahttp://reactivos.com/mailto:[email protected]:[email protected]

  • Linval DePass, Ph.D., DABT President Education: B.Sc. Georgetown University; M.Sc. University of Miami; Ph.D. University of Arkansas for Medical Sciences.

    Current: Executive Director, nonclinical Safety at Durect Corporation.

    Minerva Mercado-Feliciano, Ph.D., DABT Vice-President Education: B.Sc. Universidad de Puerto Rico-Rio Piedras; M.Sc. Indiana University; Ph.D. Indiana University. Postdoctoral Fellow at National Toxicology Program, NIEHS, NIH.

    Current: Toxicologist at US Environmental Protection Agency, Office of Pesticides, Health Effects Division.

    Elena Hernández-Ramón, M.D., Ph.D. Vice-President Elect Education: M.D. Benemérita Universidad Autónoma de Puebla; M.Sc. Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional; Ph.D. University of York. Postdoctoral Fellow at Laboratory of Cancer Biology and Genetics, National Cancer Institute/NIH. Current: Scientific Program Manager, Office of Intramural Training and Education, NIH.

    Verónica Ramírez Alcántara, Ph.D. Secretary Education: B.Sc. Benemérita Universidad Autónoma de Puebla; M.Sc./Ph.D. Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional. Postdoctoral Fellow at University of Connecticut and University of Cincinnati. Current: Research Assistant Professor at University of South Alabama Mitchell Cancer Institute.

    Ranulfo Lemus-Olalde, Ph.D., DABT Treasurer Education: B.Sc. Instituto Tecnológico de Estudios Superiores de Monterrey, M.Sc. Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional; Sc..D. Tulane University; Postdoctoral Fellow at University of Pittsburgh. Current: Health, Safety and Environmental Director of the International Tungsten Industry Association. Principal Toxicologist at Advanced Testing Laboratory, Inc.

    Silvia B. Moraes Barros, Ph.D. Councilor Education: PharmD University of São Paulo, MSc Analytical Toxicology University of São Paulo, Ph.D. Toxicology University of São Paulo. Current: Senior Professor University of São Paulo

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    Meet the Executive Board that has led HOT to reach more goals in this year!!!

    HOT Executive Board

    Continued on following page

  • Azita Cuevas, Ph.D. Councilor Education: B.A./B.Sc. University of Colorado; MPH New York Medical College; Ph.D. New York University School of Medicine.. Current: Senior Research Toxicologist at PepsiCo, Scientific Affairs Division.

    Betzabet Quintanilla, Ph.D. Councilor Education: Ph.D. Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional; Postdoctoral Fellow at National Cancer Institute- NIH/University of Maryland at Baltimore. Current: Assistant Professor at the Department of Toxicology of the Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional.

    Maria E. Gonsebatt, Ph.D. Councilor to Sister Organizations Education: Ph.D. Universidad Nacional Autónoma de México.

    Current: Professor at the Instituto de Investigaciones Biomédicas at the Universidad Nacional Autónoma de México.

    Teresa de Jesús Palacios, Ph.D. Postdoctoral Representative

    Education: B.Sc. Universidad Autónoma de Tlaxcala; M.Sc. Fundación Universidad de las Americas Puebla; Ph.D. Benemérita Universidad Autónoma de Puebla-Fundación Universidad de las Americas Puebla. Current: Postdoctoral Fellow at Laboratory of Medical Microbiology and Biotechnology, Fundación Universidad de las Americas Puebla.

    Federico L. Sinche, M.Sc. Graduate Student Representative Education: B.Sc. Universidad Politecnica del Litoral; M.Sc. Oregon State University.

    Current: Ph.D. student at Southern Illinois University.

    Betina J. Lew, Ph.D. Past President, 2013-2014. Education: B.Sc. São Paulo State University; M.Sc. The Hebrew University of Jerusalem; Ph.D. Michigan State University and Sao Paulo State University; Postdoctoral Fellow at The University of Rochester.

    Current: Senior Toxicologist at Church and Dwight Co., Inc.

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    Announcements

    The Sociedad Mexicana de Toxicología (SOMTOX), in combination with IUTOX, is holding the XIV International Congress of Toxicology in October 2016. This is the first time that an International Congress of Toxicology will be held in Mexico, and in Latin America, so what a better way to celebrate such event that having it in the beautiful city of Mérida, Yucatán, the gateway to the Mayan World. The Congress will be a “green” event with the theme: “Toxicology and Global Sustainability”. You can find more information at http://www.ict-mexico2016.org

    The Sociedade Brasileira de Toxicologia (SBTOX), in combination with IUTOX, is holding the IX Congress

    of Toxicology in Developing Countries (9th CTDC) in Natal, Brasil during November 2015. The Congress will be held in conjunction with the XIX Brazilian Congress of Toxicology, the bieenal meeting for the Sociedade Brasileira de Toxicologia. IUTOX will provide fellowships to individuals to participate in 9th CTDC. An abstract for a scientific presentation in the 9th CTDC must be submitted to be eligible for a fellowship. More information will be made available on abstract submission and award application procedure early in 2015. More information can be found at the following: http://iutox.org/ctdc.asp and http://www.sbtox.org.br/

    Toxenlaces is the newsletter that informs Hispanic toxicologists in the United States and the international Spanish and Portuguese-speaking scientific communities about important toxicological events and issues occurring in our countries. It is electronically published and distributed to our membership and Sister Organizations in Ibero-America. Toxenlaces disseminates critical dates for events, health perspectives, and funding and training opportunities. It serves as a toxicology forum for our members and other partner organizations, engages in educational outreach to the Hispanic communities and provides the essential elements to support networking among Hispanic toxicologists.

    Toxenlaces is open to receive collaborations from HOT and SOT members, and Sister Organizations. You can collaborate with short scientific articles, news or notes related with toxicology. Other ways to collaborate is by nominate your peers or yourself for the sections Featured Trainee and When I Grow Up. For more information about collaborating with Toxenlaces send an email René Viñas –Trillo (Toxenlaces Editor) at [email protected]

    Follow us 24/7 on Facebook at: http://www.facebook.com/hispanicorganizationoftoxicologists. Don’t forget to visit also the SOT Facebook page: http://www.facebook.com/pages/Society-of-Toxicology-SOT/163627880427831?fref=ts

    HOT wants you to be part of the organization! To make it available to everyone, HOT accepts applications from non-SOT members to become HOT members. Yes, that is right!! You only have to have the desire to collaborate with and be part of our great organization.

    Your HOT membership provides you with valuable resources throughout your scientific career as for networking through the largest Hispanic toxicologist community, giving you opportunity for Travel Awards or serving as a mentor to the young Hispanic toxicologists; besides you receive the Toxenlaces newsletter every two months.

    Application and more information can be found at Non-SOT Member Application. So, what are you waiting for? We are looking forward to receiving your application today!!

    http://www.ict-mexico2016.org/http://iutox.org/ctdc.asphttp://www.sbtox.org.br/mailto:[email protected]://www.facebook.com/pages/Society-of-Toxicology-SOT/163627880427831?fref=tshttp://www.facebook.com/pages/Society-of-Toxicology-SOT/163627880427831?fref=tshttp://www.toxicology.org/isot/sig/hot/doc/HOT_NonSOTMemberApplication2012.pdf

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    Current: Scientific Program Manager, Office of Intramural Training and Education, NIH.