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New sentinel node detection method combining contrast-enhanced US and dye guidance: An animal studyOmoto K, Taniguchi N, Itoh K, Hozumi Y, Jichi Medical School,Clinical Laboratory Medicine, Japan; Jichi Medical School, Surgery,Japan

Objectives: The purpose of this study was to determine whethersentinel lymph nodes (SLNs) could be identified by a combination ofcontrast-enhanced (CE) ultrasonography (US)-guided and dye-guidedprocedures in animals.Methods: Seven pigs under general anesthesia and were injectedsubcutaneously in the neck, three with 2 ml saline and four with 2 mlof 5% patent blue violet solution 0.4 ml � hydroxyethylated starch(Salinhes®) solution (PB � HS) 1.6 ml. The regional lymph nodes(LNs) were observed by US, and blue-dyed LNs were found after theskin was cut, situated as shown by US.Results: The LNs of the pigs given saline were unchanged, but in thepigs receiving PB � HS, the echo level in the LNs nearest the injectionsite was altered, and a clear contrast with the surrounding tissuesresulted. The area of the relevant LN in each PB � HS-injected pigincreased significantly (t-test: p � 0.01) (from 25.7, 39.6, 9.36 and70.2; mean 36.2, to 50.7, 65.5, 21.1 and 98.3; mean 58.9, respectively),and these enlarged LNs were easily found by CE-US. When excisedunder US guidance, all were dyed blue, indicating that all were SLNs.Conclusions: This suggests that this combination of CE-US-guidedand dye-guided procedures is a simple and speedy method of detectingSLNs.

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Ultrasonographic differentiation of the cervical lymph nodesLee EJ, Park NH, Oh HE, Park CS, Kim MS, Park SI, Ryu JA,Department of Radiology, Myongji Hospital, Kwandong University,Korea; Department of Pathology, Myongji Hospital, KwandongUniversity, Korea

Grey scale and Doppler sonography play an important role in assess-ment of cervical lymphadenopathy. The useful ultrasound features thathelp distinguish between the causes of neck lymphadenopathy, includ-ing grey scale and Doppler features, are the distribution, location, size,shape, internal architecture, intranodal necrosis, absence of hilar struc-ture, calcification, edema of soft tissue, nodal matting and distributionof vascularity. The purpose of this article is to illustrate the ultrasoundfeatures of normal and abnormal cervical lymph nodes. (1) Normal andreactive lymph nodes. (2) Malignant lymph nodes: metastatic node andlymphoma. (3) Tuberculous lymphadenitis. (4) Kikuchi’s disease. (5)Kimura’s disease. (6) Castleman’s disease. (7) Toxoplasmic lymphad-enitis. (8) Bacterial lymphadenitis. (9)Viral lymphadenitis. Ultrasoundis useful in distinguish between the causes of neck lymphadenopathy.

3314

Value of intraoperative ultrasonography in neurosurgeryYi W, Fudan University Affiliated Huashan Hospital, China

Objectives: To evaluate the ultrasound’s role in neurosurgery opera-tion.Methods: Two hundreds sixty-four patients under neurosurgery werestudied. We evaluate the ultrasound’s role in detecting, locating andmonitoring remainder of tumor during operation.Results: All tumors were detected by ultrasound in neurosurgeryoperation. Boundaries of tumors were displayed clearly. After opera-tion, ultrasound is also useful in detecting remainder of the tumors.

Conclusions: With intra-operation ultrasound in neurosurgery, we mayshorten operation time and reduce normal brain’s trauma. It may enjoywider clinical application in neurosurgery operation.

3315

Ultrasonic estimating of accommodation changes after thetreatment of myopic eyesKriauciuniene L, Paunksnis A, Kaunas Medical University, Lithuania

Objectives: The goal of our work was to evaluate the anatomicmeasurement of the eye using precise ultrasonic biometry for 6- to15-year old children with myopic refraction and their changes after thetreatment with the low frequency electromagnetic field.Methods: Seventy myopic children (140 eyes) with the accommoda-tion spasm were estimated with the ultrasonic biometry before and afterthe treatment. The average of the myopic children ranged between 6and 15 years and the size of the refraction was from �1.0 to �3.0 D.Results: After the treatment the clinical size of the refraction reducedbut only statistic unreliably. Before the treatment the myopic children’scrystalline lens when fixing the sight to the length and to the nearnessdidn’t change. After the course of the treatment the opportunities of theaccommodation of the myopic children have improved, it shows thestatistically reliable changes in the eye measurements, when fixing thesight to the length and to the nearness (the average excursion of thecrystalline lens was 0.187 � 0.152 mm first group and 0.181 � 0.153mm second group; in both cases p � 0.001).Conclusions: After the treatment children’s myopic eyes by low fre-quency electromagnetic field during accommodation the excursions oflens crystalline thickness significantly increases (p � 0.05 in all cases).

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Doppler ultrasonographic parameters for prediction ofcerebrovascular reserve in patients with acute strokeLee HJ, Jung HY, Lee J, Kim YS, Kang DS, Kyungpook NationalUniversity Hospital, Korea

Objectives: We investigated Doppler ultrasonographic (US) parame-ters of the patients with acute stroke to predict the cerebrovascularreserve (CVR) measured by acetazolamide-challenged Tc-99m ECDbrain SPECT.Methods: We compared the Doppler US parameters including peaksystolic velocity (PSV), end diastolic velocity (EDS), angle correctedtime averaged flow velocity (TAV), geometric stenosis, flow volume(FV) at the extracranial cerebral arteries and total cerebral blood flowvolume (TCBFV) between 46 cases of preserved and 65 cases ofimpaired CVR by SPECT. FV of each artery can be calculated as theproduct of TAV and cross-sectional area of the circular vessel. The sumof FV of extracranial arteries determined TCBFV.Results: In cases of preserved CVR, the PSV and the TAV of ipsilat-eral and contralateral CCA were higher, and FV of both ICA and TCBFwere increased (p � 0.05, t-test). The severity of ipsilateral ICAstenosis, FV of both ICA and TCBF were significant to predict CVR (p� 0.05), and the accuracy for prediction was 72.1% by logistic regres-sion analysis. The ROC curves indicated better performance for FVmeasurement compared with geometric stenosis in prediction of CVR.Conclusions: Doppler US parameters including FV measurement wasuseful for prediction of CVR.

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Clinical study of percutaneous quantified ethanol injection in thetreatment for recurrent hepatocellular carcinoma withintercurrent hepatocirrhosisLin L, Lin X-Y, Xue E-S, He Y-M, Gao S-D, Lin X-D, Wu L-Z,Union Hospital of Fujian Medical University, China

P244 Ultrasound in Medicine and Biology Volume 32, Number 5S, 2006