4. basic principles of growth

8/3/2019 4. Basic Principles of Growth

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Chondrogenesis

Formation of cartilage:

Chondroblasts produce intercellular matrix

Cells become encased in matrix and becomechondrocytes

Chondrocytes enlarge, divide and produce matrix(interstitial growth)

New chondrocytes differentiate from surfacemembrane (appositional growth)

Matrix remains uncalcified


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Formation

Bone formation from undifferentiated mesenchymal

tissue

Process begins in 8th week IUL

Osteoblasts from ectomesenchyme produce osteoidtissue

Cells become encased in matrix and becomeosteocytes

Blood vessels retained within spaces and develophaversian system

Osteocytes lose capacity to produce osteoid

Periosteum produces more osteoid tissue(appositional growth)

Osteoid calcifies

Essential membrane covers bone


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+ + + + + + +++

- - - - --- - - -

Inferior Relocation of Palate


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4. basic principles of growth

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