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B. Riley FBR Consumer & Media Conference

October 3, 2019

Cautionary Notes

2

Cautionary Notes

FORWARD-LOOKING STATEMENTS

This presentation and oral statements accompanying this presentation contain forward-looking statements, andany statements other than statements of historical fact could be deemed to be forward-looking statements. These forward-looking statements include, among other things, statements regarding future events, such as expected revenue,gross margin and EBITDA in 2019 and beyond, including related growth rates, the anticipated development, scalingand commercialization of Amyris’s product pipeline and introduction of new products, including HMOs, vitamins andcannabinoid ingredients, including the cost and purity of such products, expected growth of Amyris’s Clean Beauty, babyskincare, Sweetener and F&F businesses, the anticipated size and growth of the global beauty and personal care market,expected distribution channels for Amyris’s baby skincare products, the anticipated size, growth and composition of theglobal baby care market, the expected size, growth and composition of the global psychoactive market and the U.S. andglobal cannabinoid markets, anticipated sources of liquidity and improvements to Amyris’s capital structure and balancesheet, and expectations regarding Amyris’s financial and operational results and ability to achieve its business plan in 2019and beyond. These statements are based on management’s current expectations and actual results and future events maydiffer materially due to risks and uncertainties, including risks related to Amyris’s liquidity and ability to fund operating andcapital expenses, risks related to potential delays or failures in development, production and commercialization of products,risks related to Amyris's reliance on third parties, and other risks detailed from time to time in filings Amyris makes with theSecurities and Exchange Commission, including Annual Reports on Form 10-K, Quarterly Reports on Form 10-Q andCurrent Reports on Form 8-K. Amyris disclaims any obligation to update information contained in these forward-lookingstatements, whether as a result of new information, future events, or otherwise.

Copyright © 2019 Amyris, Inc. All rights reserved

Making the

World Healthier Make good. No compromise.®

3Copyright © 2019 Amyris, Inc. All rights reserved

© 2019 Amyris, Inc. All Rights Reserved.

Consumers are Demanding Sustainability

“The Flavor & Fragrance industry is experiencing an increasing need for natural ingredients,” says Julia Raquet, who heads BASF’s Aroma Ingredients business. “But

fluctuating product quality, availability and sustainability are constant challenges for our customers. By entering the market with biotechnology-based aroma ingredients,

we intend to provide our customers with high-quality products to respond to the current market challenges.”*

“BASF is known for its high-quality standards, traceability and excellent regulatory know-how,” says ToineJanssen, founder of Isobionics. “By combining our biotech-based product portfolio and strong development

pipeline with BASF’s expertise and its global market reach, we can provide the natural aroma ingredients market with even more innovations – and boost our growth.”*

*Source: BASF News Release, September 2019

4

FERMENTATION MAKES NATURAL

SUSTAINABLE

Copyright © 2019 Amyris, Inc. All rights reserved 5

Growing market size demand of squalane (CAGR** 10%)

Full Year 2018:Neossance™ market share** = >40%

OLIVE squalane

NEOSSANCEsqualane (sugar)

Our squalane has offset the demand of 4M sharks*

Highest purity & most sustainable squalane

87-92%94-95%PURITY

Before & After Amyris: The Squalane Evolution

* The demand of 4M sharks harvested for shark squalane ** CAGR is based on Allied Market Research for squalene market*** Purity data from Aprinnova technical team


BisabololRenewably sourcedwith a reduced ecological footprint

230x less land to produce the same quantity

Hectares to produce 1 ton

Sugarcane.Candeia Tree.

12 years to grow each tree

1 year to grow and harvest

Source: Givaudan Active Beauty, Bisabolife® brochure

Before & After Amyris: Disrupting the Fragrance Industry

7

© 2019 Amyris, Inc. All rights reserved.

Amyris is Delivering on the Promise of Synthetic Biology

1 Engineer microbial factories

Emeryville, CA, USA(near San Francisco)

2Produce ingredients using our industrial fermentation technology

Brotas, BrazilCMOs

3Commercialize through collaboration partners and direct to consumer

8

#1 Synthetic Biotechnology

Platform

Fully integrated production of high

value products

Proven Commercial Platform

Ingredients Consumer

Partners Consumer Brands

Market Leadership

Making Health and Beauty Sustainable

• HMOs

• Vitamins

• Cannabinoids

• Rose, Inc.

• Clean Beauty

• Health & Wellness

• F&F Ingredients

Disruptive Pipeline


$0$20$40$60$80

$100$120$140

Skincare Hair Care ColourCosmetics

Men'sGrooming

Fragrances Oral Care Bath andShower

Deodorants Sets/Kits Baby andchild-specific

Products

Sun Care Depilatories

10*Source: Euromonitor 2017, **Source: Research and Markets.com, 2019 Copyright © 2019 Amyris, Inc. All rights reserved

Beauty & Personal Care

Beauty & Personal Care Global Market Sizes by Health & Personal Care category* (2017, $B)

This Market is Expected to Surpass $716B by 2025**

= markets Amyris participates in

4%6%

2%5%

3%6%

5%6%

3%6%

3%5%

2%6%

4%8%

5%6%

2%6%

3%5%

1%4%

2015-2017 2017-2021E

CAGR


Launched September 4, 2019

18

Clean, Sustainable

Re

tail

Pri

ce

(by

mL

)

20


Addressing global problems:Diabetes Obesity

Meeting Millennial demands:All-Natural Zero CaloriesNon GMO

AMYRIS SWEETENER IS THE RIGHT SOLUTION AND AT THE RIGHT TIME


AMYRIS IS DISRUPTING THE SWEEETNER MARKETSWEETNESS EQUIVALENCY

350-500 grams of sugar* 1 gram of

YTD sales is offsetting ~20B calories from sugar

*depending on application


MILLIONS OF MILLENNIALS SAID…….We believe in doing

I Love Sugar

Sugar Is An Addiction

Sugar is Linked to Diabetes

Use with Moderation

26


SWEET FOR ME. SWEET FOR THE PLANET.100 % SWEET

0 bitter aftertaste

0 glycemic index

0 calories

0 GMO

fermented for a healthy gut

100% SUSTAINABLE

responsibly grown sugarcane

10x less farmland to produce

1 clean fermentation process

all recycled cane-based packaging

0 waste (almost, we’re working on it)

2727

© 2019 Amyris, Inc. All rights reserved. 28

Cannabinoids:

Our Next MegaMarket

Source: Yoga Journal


Cannabinoids – The New Legal Psychoactive Opportunity

Legal Cannabis Global Spending Forecastd (US$)

By 2025: $66B2019-2025 CAGRe: 24%

Common Legal Psychoactive Markets(Global Demand US$)

Are Cannabinoids the next mega market?

Future Growth CAGR

Alcohola By 2026: $1,864B

2017-2026:4%

Tobaccob By 2026: $1,012B

2019-2026:5%

Coffeec By 2024: $15B

2018-2024:6%

Sources: PR Newswire, Market Watch, Allied Market, Statista, Grand View Research 29


Our Cannabinoid Opportunity

1) Supplier of choice for global brands

2) Clean ingredient for our beauty brands

3) Build leading over-the-counter brand for pain, anxiety and sleep supplement - a leader in sustainable health

30


Breakout opportunity in fermentation - derived cannabinoids

Source: Paradigm Capital Inc.

Outdoor Grow Indoor Grow Biosynthesis

~CAPEX >$10 Million > $30 Million $4.5 Million

Cycle times 4-6 months 3-4 months Semi-continuous

~COGS ($/kg) $3,000-5,000 $5,000-$10,000 $500-$1,500

• $300M cannabinoids collaboration with LAVVAN; expect to commercialize CBD in 2020.• Capable of developing CBD and other cannabinoids at significant cost advantage with

ultra purity, which is essential for brand adoption in this market.

Copyright © 2019 Amyris, Inc. All rights reserved31

Advantaged Portfolio Delivers Strong Growth & Expanding Profitability

2018 20192017* Adjusted for loss making product sales on contracts and one time revenues

Gross Margin % 49% 52% 55%- 65%

32

ProductLicense/Royalties/Collab

Product CAGR = 98%


*Excludes Vitamin E and one time Licenses 33 Copyright © 2019 Amyris, Inc. All rights reserved

Collaborations %

Products %

Percentage of Total Dollar Contribution from Gross Margin to cover Operating Expenses

Actual Plan

$0

$EBITDA

$M

Revenue Mix shifting to Recurring and Delivering a Sustainable Business

Our Platform is Delivering

Branded Product Sales +190%

Ingredient Sales +65%

2017-2019 REVENUE CAGR*

Copyright © 2019 Amyris, Inc. All rights reserved34

SqualaneHemisqualane

Derived Fragrances

Farnesene* Derivatives

Fermented* Products

RebM

BisabololOther Fragrances

* Excludes discontinued products and Vitamin E


© 2019 Amyris, Inc. All Rights Reserved.

Evaluating the Competitive Landscape

*Total equity capital investments do not include any debt instrumentsSources: Forbes, Business Wire, PR Newswire, Industry Expert Source, SF Business Times, Tech Crunch

Market Cap / Valuation

Total Equity Capital

Invested

2019Annual

Revenue

Annual Growth Rate (2018-2019)

Products Commercialized

at Industrial Scale

Commercial Visibility

Amyris $490M ~$1B* $150M(fcst) 134% 9

Gingko $4B(est) $719M $80M(est) 100% 2(est)

Zymergen $1B+(est) $574M N/A N/A N/A

35


Warrants are a strong source of cash from long term investors

85%

12%

3%

103M62M

16M

10M

Warrants Held by Insiders vs. Others103M Total Shares Issued

191M Fully Diluted88M Reserved for Issuance

Insider Warrants

Others

Not likely to be exercised/converted

Total Outstanding Shares

Reserved for Employee-Related Plans

Reserved for warrants/convertible notes/preferred stock (excluding amount not likely to be exercised/converted)

Amount not likely to be exercised/converted


Notes:•Estimated warrant exercise potential proceeds of up to $212M subject to certain conditions•$64M expected to convert into equity by end of 2019: (Foris $51.5M, Schottenfeld $12.5M) - equivalent to approximate 20M warrants converting into shares

Make good.No compromise.

• Our ingredients are inside over $7B of consumer retail purchases sold through 3,000 of the world’s leading personal care and beauty brands

• Our Biossance Skin Care Brand is the fastest growing Skin Care Brand in North America

• We have the leading product in the natural Sweetener market. We are committed to a healthier planet and a sweet life for all!

• Most profitable & fastest growing product portfolio in the industry

Good for People

Good for the Planet

Good for Business

™


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