PMIDOWN STATDA IS IS VI IP DP TI irin:

24520278 NLM Publisher 20140212 1792-0981 (Print) 1792-0981 (Linking) 7 3 2014 Mar Effectiveness of cilostazol in transient ischemic attack refractory to asp A report of two cases. PG - 739-741 AB - Transient ischemic attack (TIA) is a warning of impending ischemic stroke. It provides an important therapeutic time window in which appropriate interve ntion may prevent permanent neurological injury. The anti-platelet agent, aspiri n, is an option for reducing the risk of stroke following TIA. However, for pati ents who are not responsive to aspirin, cilostazol may be an effective treatmen t. The current study presents two cases of TIA that were refractory to aspirin bu t were successfully treated with cilostazol. In case 1, an 83-year-old female pat ient suffered from episodes of weakness and numbness of the left extremities. A spirin alone or aspirin in combination with clopidogrel were not effective. Anticoagulation therapy with low molecular heparin decreased the frequency of ischemic episodes with complete remission following antiplatelet therapy w ith cilostazol. In case 2, a 51-year-old male presentedwith episodes of paroxy smal weakness of the left extremities with dysarthria. Antiplatelet therapy wit h aspirin was initiated. Eight episodes of ischemic attack recurred on the s eventh day following admission. After the change of the antiplatelet agent to cilostazol, no ischemic episodes recurred, with the exception of three on the first day. This study suggested that cilostazol may be efficacious in the prevention of ischemic stoke following TIA of a non-cardiac origin that wa s not responsive to aspirin. FAU - Lin, Gaoping AU - Lin G AD - Department of Neurology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, P.R. China. FAU - Ren, Dongdong AU - Ren D AD - Department of Neurology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, P.R. China. FAU - Guo, Shunyuan AU - Guo S AD - Department of Neurology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, P.R. China. FAU - Geng, Yu

AU - Geng Y AD - Department of Neurology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, P.R. China. LA - ENG PT - JOURNAL ARTICLE DEP - 20131231 TA - Exp Ther Med JT - Experimental and therapeutic medicine JID - 101531947 PMC - PMC3919941 OTO - NOTNLM OT - aspirin OT - cilostazol OT - transient ischemic attack EDAT- 2014/02/13 06:00 MHDA- 2014/02/13 06:00 CRDT- 2014/02/13 06:00 PHST- 2013/08/07 [received] PHST- 2013/12/23 [accepted] PHST- 2013/12/31 [epublish] AID - 10.3892/etm.2013.1468 [doi] AID - etm-07-03-0739 [pii] PST - ppublish SO - Exp Ther Med. 2014 Mar;7(3):739-741. Epub 2013 Dec 31. PMIDOWN STATDA IS IS VI IP DP TI 24518409 NLM In-Data-Review 20140212 1537-4505 (Electronic) 1531-7129 (Linking) 35 3 2014 Mar Side-to-End Hypoglossal to Facial Anastomosis With Transposition of the Intratemporal Facial Nerve. PG - 509-13 LID - 10.1097/MAO.0b013e3182936bcf [doi] AB - OBJECTIVE: To describe results in a large series of patients using a recen t variation of hypoglossal-facial nerve anastomosis (HFA) in which the intratemporal facial nerve segment is used, obviating the need for a senso ry nerve "jump graft." STUDY DESIGN: Retrospective chart review. SETTING: Ter tiary neurotologic referral center. PATIENTS: Nineteen patients (12 female/7 mal e subjects) with facial paralysis because of posterior fossa surgery for tum or (n = 15), Bell's palsy (n = 1), facial neuroma (n = 1), hemangioma (n = 1), and trauma (n = 1) who underwent HFA from 1997 to 2011, with at least 1-year follow-u p. Mean age at surgery is 47.4 years (range, 11.2-83 yr). Mean follow-up is 4.0 ye ars. INTERVENTION: Side-to-end hypoglossal to facial anastomosis with transposi tion of the intratemporal facial nerve (swingdown HFA). MAIN OUTCOME MEASURE: House-Brackmann (H-B) facial nerve grade. RESULTS: Seven patients (36.8%) achieved an H-B Grade III, 9 patients (47.4%) a grade IV, and 3 patients (

15.8%) a grade V at last follow-up. No patients complained of dysphagia, dysarthr ia, or had evidence of oral incompetence. One patient complained of mild tongue weakness. Age at time of HFA (p 0.60, p/= 12 h in 77% (10/13). We reported a 14-year-old female patient presenting with altered sensorium that progressed to a 'locked-in' state due to idiopathic BAO who made a full clinical recovery after successful mechanical thrombectomy at 24 h fo llowing symptom onset. Acute neuro-interventional therapy for paediatric BAO can r esult in complete neurological recovery despite the presence of severe neurologi cal deficits and a prolonged period of time from symptom onset to clinical dia gnosis. CI - (c) 2011 The Authors. Journal of Paediatrics and Child Health (c) 2011 Paediatrics and Child Health Division (Royal Australasian College of Physi cians). FAU - Taneja, Sanjeev R AU - Taneja SR AD - Department of Neurology, Liverpool Hospital, Liverpool, Sydney, New South Wales, Australia.

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Hanna, Ibrahim Hanna I Holdgate, Anna Holdgate A Wenderoth, Jason Wenderoth J Cordato, Dennis J Cordato DJ eng Case Reports Journal Article Review 20110131 Australia J Paediatr Child Health Journal of paediatrics and child health 9005421 IM Adolescent Female Humans *Mechanical Thrombolysis Vertebrobasilar Insufficiency/diagnosis/*therapy 2011/02/01 06:00 2012/03/02 06:00 2011/02/01 06:00 2011/01/31 [aheadofprint] 10.1111/j.1440-1754.2010.01974.x [doi] ppublish J Paediatr Child Health. 2011 Jul;47(7):408-14. doi: 10.1111/j.1440-1754.2010.01974.x. Epub 2011 Jan 31.

20424549 NLM MEDLINE 20100428 20100805 20110614 1643-3750 (Electronic) 1234-1010 (Linking) 16 5 2010 May Speech intelligibility in cerebral palsy children attending an art therapy program. PG - CR222-31 AB - BACKGROUND: Dysarthia is a common sequela of cerebral palsy (CP), directly affecting both the intelligibility of speech and the child's psycho-social adjustment. Speech therapy focused exclusively on the articulatory organs does not always help CP children to speak more intelligibly. The program of art therapy described here has proven to be helpful for these children. MATERIAL/METHODS: From among all the CP children enrolled in our art thera py program from 2005 to 2009, we selected a group of 14 boys and girls (avera ge age 15.3) with severe dysarthria at baseline but no other language or cognitiv e disturbances. Our retrospective study was based on results from the Audito ry

Dysarthria Scale and neuropsychological tests for fluency, administered ro utinely over the 4 months of art therapy. RESULTS: All 14 children in the study gr oup showed some degree of improvement after art therapy in all tested paramete rs. On the Auditory Dysarthia Scale, highly significant improvements were noted i n overall intelligibility (p