5.3 regulation of the cell cycle key concept cell cycle regulation is necessary for healthy growth
TRANSCRIPT
![Page 1: 5.3 Regulation of the Cell Cycle KEY CONCEPT Cell cycle regulation is necessary for healthy growth](https://reader036.vdocument.in/reader036/viewer/2022062407/56649e545503460f94b4b8df/html5/thumbnails/1.jpg)
5.3 Regulation of the Cell Cycle
KEY CONCEPTCell cycle regulation is necessary for healthy growth.
![Page 2: 5.3 Regulation of the Cell Cycle KEY CONCEPT Cell cycle regulation is necessary for healthy growth](https://reader036.vdocument.in/reader036/viewer/2022062407/56649e545503460f94b4b8df/html5/thumbnails/2.jpg)
5.3 Regulation of the Cell Cycle
Internal factors• kinases change the activity of other molecules by adding
a phosphate group• cyclins –are rapidly made and destroyed at different
points of the cell cycle. This helps cells advance to different stages of the cells cycle.
External factors • cell to cell contact • growth factors which stimulate internal factors that affect
the cell cycle (cell division)
![Page 3: 5.3 Regulation of the Cell Cycle KEY CONCEPT Cell cycle regulation is necessary for healthy growth](https://reader036.vdocument.in/reader036/viewer/2022062407/56649e545503460f94b4b8df/html5/thumbnails/3.jpg)
5.3 Regulation of the Cell Cycle
Internal and external factors regulate cell division.
• External factors include physical and chemical signals.• Growth factors are proteins that stimulate cell division.
– Most mammal cells form a single layer in a culture dish and stop dividing once they touch other cells.
![Page 4: 5.3 Regulation of the Cell Cycle KEY CONCEPT Cell cycle regulation is necessary for healthy growth](https://reader036.vdocument.in/reader036/viewer/2022062407/56649e545503460f94b4b8df/html5/thumbnails/4.jpg)
5.3 Regulation of the Cell Cycle
• Carcinogens are substances known to promote cancer.• Ex. Air pollution, tobacco smoke, mutated genes carried
by viruses.
• Standard cancer treatments typically kill both cancerous and healthy cells.
![Page 5: 5.3 Regulation of the Cell Cycle KEY CONCEPT Cell cycle regulation is necessary for healthy growth](https://reader036.vdocument.in/reader036/viewer/2022062407/56649e545503460f94b4b8df/html5/thumbnails/5.jpg)
5.3 Regulation of the Cell Cycle
• Cancer cells do not carry out necessary functions.
• Cancer cells come from normal cells with damage to genes involved in cell-cycle regulation.
![Page 6: 5.3 Regulation of the Cell Cycle KEY CONCEPT Cell cycle regulation is necessary for healthy growth](https://reader036.vdocument.in/reader036/viewer/2022062407/56649e545503460f94b4b8df/html5/thumbnails/6.jpg)
5.3 Regulation of the Cell Cycle
Cell division is uncontrolled in cancer.
• Cancer cells form disorganized clumps called tumors-disorganized clumps of cancer cells that do not carry out normal functions
cancer cellbloodstream
normal cell
– Benign tumors remain clustered and can be removed.– Malignant tumors metastasize, or break away, and can
form more tumors.
![Page 7: 5.3 Regulation of the Cell Cycle KEY CONCEPT Cell cycle regulation is necessary for healthy growth](https://reader036.vdocument.in/reader036/viewer/2022062407/56649e545503460f94b4b8df/html5/thumbnails/7.jpg)
5.3 Regulation of the Cell Cycle
– a normal feature of healthy organisms– caused by a cell’s production of self-destructive
enzymes
1.occurs indevelopmentof infants
2.Helps rid the
body of
unhealthy cells
webbed fingers
• Apoptosis is programmed cell death.