560 585 588 613 616 641 644 669 1 200 400 600 706 (aa) 22129 btb domain zinc-finger domains bcl6...
DESCRIPTION
PGL3-PKM Con WT P14S S22R R49H K60R D78E R112C P184S Q322L S326L S357R R377L C387F I391L R399L R402H T403N H404R G406V P409S C412Y K424N K424T R430W T461M L463M Y466D A522T E541K G562DD576V pGL3- PKM Luc/Rennila * * * * * * * * * * * * * BTB domain Zinc-finger domains Liu et al. Supplementary Figure 3TRANSCRIPT
560 585 588 613 616 641 644 669
1 200 400 600 706 (aa)
22 129
BTB domain Zinc-finger domains
BCL6
Num
ber o
f sam
ples
m
utat
ed
Num
ber o
f mut
atio
ns
per
10 a
min
o ac
ids
0 100 200 300 400 500 600 700(aa)
0
2
4
6
8
10
Liu et al. Supplementary Figure 1
P<0.05
P>0.05
a
b
c
1 100 200 300 400 500 600 673 (aa)
25 125 532 555 561 584 589 610 (aa)
BTB domain Zinc-finger domains
PLZF(ZBTB16)
Num
ber o
f sam
ples
m
utat
ed
Num
ber o
f mut
atio
ns
per
10 a
min
o ac
ids
0 100 200 300 400 500 600 700(aa)
0
1
2
3
4 5
P<0.05
P>0.05
a
b
c
Liu et al. Supplementary Figure 2
PGL3-PKM
Con
WT
P
14S
S
22R
R
49H
K
60R
D
78E
R
112C
P
184S
Q
322L
S
326L
S35
7R
R37
7L
C38
7F
I391
L
R39
9L
R40
2H
T403
N
H40
4R
G40
6V
P40
9S
C41
2Y
K42
4N
K42
4T
R43
0W
T461
M
L463
M
Y46
6D
A52
2T
E54
1K
G56
2D
D57
6V
pGL3
-PKM
Lu
c/R
enni
la * **
* * * * ** *
*
**
BTB domain Zinc-finger domains
Liu et al. Supplementary Figure 3