6 april 19733 - sciencescience.sciencemag.org/content/sci/180/4081/local/ed-board.pdfcalling song....

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6 April 1973 3 Volume 180, No. 4081 r 0 LETTERS Flora of North America: A. W. Galston; Insulin Synthesis: S. A. Lakoff; Arms Control: J. Ledierberg and S. D. Drell; One Man's Family: R. H. Shanntioni; Frog Health: D. S. Paperni-aster and E. Gralla; 1,atin American Development: L. Tosi; P. G. Keenev ................. B3io,v1-Hot. Blow-Cold Educational Policies .............................. ARTICLI:S A Distilling System for Purer Water: K. Hickmtian, I. White, E. Stark ........... Enzymatic Interconversion of Active and Inactive Forms of Enzymes: H. L. Segal ................................................ On the Enzymology of Amino Acid Transport: A. Mei.ster................... NEWS AND COMMENT RESEARCH NEWS BOOK REVIEWS Soviet-,Americaan Science Accord: Could Dissent Deter Detente? .............. ilcibic des: Agent Orange Pulled from Vietnam May Go to the SoLlth Americans . 111mmUnolo\N. T\o ImmuLne Systems Capture Attention ...................... i RTS: Surveying Earth's Resources from Space .......................... Impact of Insulin on Metabolic Pathways, reviewed by A. Rubenstein, Glucagon, P. W. Felts; Behaviour of Wolves, Dogs and Related Canids, L. K. Corbett; Aquaculture, J. D. Costlow; Biology of Halophytes, B. OsiuionId ............ REPORTS Helium Flux from the Earth's Mantle as Estimated from Hawaiian Fumarolic Degassing: J. J. Nailuthton et al. . . . . . . . . . . . . . . . . . . . . . . . . . . . Ductile Superconducting Copper-Base Alloys: C. C. T'sitei ................. 40 43 45 49 52 55 57 *0-O RD oF 0 DIRESCTORS OLENN T. SEABORG LEONARD M. RIESER ROGER REVELLE RICHARD H. BOLT BARRY COMMONER Retiring President, Chairman President President-Elect LEWIS M. BRANSCOMB EMILIO Q. DADDARIO CHAIRMEN AND MATHEMATICS (A) PHYSICS (B) CHEMISTRY (C) ASTRONOMY (0) SECRIlTA:RIES OF Lipman Bers Edwin M. McMillan Thomas E. Taylor Fra:nk D. Drake F. A. Ficken Rolf M. Sinclair Leo Schubert Arlo U. Landolt "AS SECTIONS PSYCHOLOGY (J) SOCIAL AND ECONOMIC SCIENCES (K) HISTORY AND PHILOSOPHY OF SCIENCE (L) Carl P. Duncan Robert K. Merton Ernest Nagel William D. Garvey Harvey Sapoisky Dudley Shapere INDUSTRIAL SCIENCE (P) EDUCATION (Q) DENTISTRY (R) PHARMACEUTICAL SCIENCES (S:,' Jacob E. Goldman Gordon Swanson Martin Cattoni Wi,lliam Heller Jordan D. Lewis Phillip R. Fordyce Sholom Peairlman John Autian DIVIISIONS ALASKA DIVISION PACIIFIC DIVISION SOMWESTERN AND ROCKY 11OUNTAI DIVISION Gunter E. Welter Irma Duncan John D. Isaacs Robert T. Orr J. Linton Gardner Marlowe Aendon President Executive Secretary President Secretary-Treasurer President Executive eSet ::SCIENCE is published weekly, except the last week in December, but with an extra issue on the fourth Tuesday in November, by the American Association for the Advancement of Science 1515 Massachusets Ave., NW, Washington, D.C. 20005. Now combined with The ScIentific 11enthly@. Second-class postage paid at Washington, D.C. Copyright 197wby the Americatn Association for the Advancement of Science. Annual subscription $20; foreign postage: Americas $3; overseas $5; air freight Europe, North Africa, Near: Est 16 single copies $1 (back issues, $2) excet G1uide to Scientific Instrnnta which is $4. School year subscription: 9 months $15; 10 months, $16.75. Member rates on trsl New rates effective 1 May 1973: Annual subscription $30; foreign postage: A:mericas $4, overseas $6, air lift to Euroje $16. Povide :4 weeks notice for change of addres,iiin and old addres and codes. Send addres label. SCIENCa is Indeed in. the Readt's Guide to PerIodIcal LIteatur.; EDITORIAL 9 13 15 25 33 ... .i. :.I.

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6 April 19733Volume 180, No. 4081 r 0

LETTERS Flora of North America: A. W. Galston; Insulin Synthesis: S. A. Lakoff;Arms Control: J. Ledierberg and S. D. Drell; One Man's Family:R. H. Shanntioni; Frog Health: D. S. Paperni-aster and E. Gralla;1,atin American Development: L. Tosi; P. G. Keenev .................

B3io,v1-Hot. Blow-Cold Educational Policies ..............................

ARTICLI:S A Distilling System for Purer Water: K. Hickmtian, I. White, E. Stark ...........

Enzymatic Interconversion of Active and Inactive Forms of Enzymes:H. L. Segal ................................................

On the Enzymology of Amino Acid Transport: A. Mei.ster...................

NEWS AND COMMENT

RESEARCH NEWS

BOOK REVIEWS

Soviet-,Americaan Science Accord: Could Dissent Deter Detente? ..............

ilcibic des: Agent Orange Pulled from Vietnam May Go to the SoLlth Americans .

111mmUnolo\N. T\o ImmuLne Systems Capture Attention ......................

i RTS: Surveying Earth's Resources from Space ..........................

Impact of Insulin on Metabolic Pathways, reviewed by A. Rubenstein, Glucagon,P. W. Felts; Behaviour of Wolves, Dogs and Related Canids, L. K. Corbett;Aquaculture, J. D. Costlow; Biology of Halophytes, B. OsiuionId ............

REPORTS Helium Flux from the Earth's Mantle as Estimated from Hawaiian FumarolicDegassing: J. J. Nailuthton et al. . . . . . . . . . . . . . . . . . . . . . . . . . . .

Ductile Superconducting Copper-Base Alloys: C. C. T'sitei .................

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*0-O RD oF0 DIRESCTORS OLENN T. SEABORG LEONARD M. RIESER ROGER REVELLE RICHARD H. BOLT BARRY COMMONERRetiring President, Chairman President President-Elect LEWIS M. BRANSCOMB EMILIO Q. DADDARIO

CHAIRMEN AND MATHEMATICS (A) PHYSICS (B) CHEMISTRY (C) ASTRONOMY (0)

SECRIlTA:RIES OF Lipman Bers Edwin M. McMillan Thomas E. Taylor Fra:nk D. DrakeF. A. Ficken Rolf M. Sinclair Leo Schubert Arlo U. Landolt"AS SECTIONS

PSYCHOLOGY (J) SOCIAL AND ECONOMIC SCIENCES (K) HISTORY AND PHILOSOPHY OF SCIENCE (L)Carl P. Duncan Robert K. Merton Ernest NagelWilliam D. Garvey Harvey Sapoisky Dudley Shapere

INDUSTRIAL SCIENCE (P) EDUCATION (Q) DENTISTRY (R) PHARMACEUTICAL SCIENCES (S:,'Jacob E. Goldman Gordon Swanson Martin Cattoni Wi,lliam HellerJordan D. Lewis Phillip R. Fordyce Sholom Peairlman John Autian

DIVIISIONS ALASKA DIVISION PACIIFIC DIVISION SOMWESTERN AND ROCKY 11OUNTAI DIVISIONGunter E. Welter Irma Duncan John D. Isaacs Robert T. Orr J. Linton Gardner Marlowe AendonPresident Executive Secretary President Secretary-Treasurer President Executive eSet

::SCIENCE is published weekly, except the last week in December, but with an extra issue on the fourth Tuesday in November, by the American Association for the Advancement ofScience 1515 Massachusets Ave., NW, Washington, D.C. 20005. Now combined with The ScIentific 11enthly@. Second-class postage paid at Washington, D.C. Copyright 197wbythe Americatn Association for the Advancement of Science. Annual subscription $20; foreign postage: Americas $3; overseas $5; air freight Europe, North Africa, Near: Est 16

single copies $1 (back issues, $2) excet G1uide to Scientific Instrnnta which is $4. School year subscription: 9 months $15; 10 months, $16.75. Member rates on trslNew rates effective 1 May 1973: Annual subscription $30; foreign postage: A:mericas $4, overseas $6, air lift to Euroje $16. Povide :4 weeks notice for change of addres,iiin

and old addres and codes. Send addres label. SCIENCa is Indeed in. the Readt's Guide to PerIodIcal LIteatur.;

EDITORIAL

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AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE

Nile Delta: The Defunct Pelusiac Branch Identified: A. Sneh and T. Weissbrod 59

Rare-Earth Manganites: Catalysts with Low Ammonia Yield in the Reduction ofNitrogen Oxides: R. J. H. Voorhoeve, J. P. Remeika, D. W. Johnson, Jr 62

Crystallographic Orientation of Clinoenstatite Produced by Deformation ofOrthoenstatite: R. S. Coe and W. F. Muller .......................... 64

Teleconnections in the Equatorial Pacific Ocean: K. Wyrtki .................. 66

Lunar Cinder Cones: T. R. McGetchin and J. W. Head ..................... 68

Mechanisms of Trace Metal Transport in Rivers: R. J. Gibbs ................. 71

Kilauea Volcano, Hawaii: A Search for the Volcanomagnetic Effect:P. M. Davis et al. ........................................... 73

Genetic Variation in a Gradient of Environmental Variability: Marine Bivalvia(Mollusca): J. Levinton ....................................... 75

Two Morphologically Distinct Blood-Brain Barriers Preventing Entry of Cytochromec into Cerebrospinal Fluid: T. H. Milhorat, D. A. Davis, B. J. Lloyd, Jr .. . 76

Immunologic Manipulation of Metastases due to Herpesvirus Transformed Cells:R. Duij, E. Doller, F. Rapp ..................................... 79

Translocation Trisomic Mice: Production by Female but Not Male TranslocationCarriers: E. M. Eicher ........................................ 81

Genetic Control of Song Specificity in Crickets: R. R. Hoy and R. C. Palul ........ 82

A1-Tetrahydrocannabinol: Effects on Mammalian Nonmvelinated Nerve Fibers:R. Byck and J. M. Ritchie ...................................... 84

ASSOCIATION AFFAIRS Nutrition and New Food Technology: R. Rojas and O. Paredes-Lopez; EfJectsof Malnutrition on Human Development: S. Ziubiran; Drug Addiction:U. Estrada; Natural Products: T. E. Taylor..........................

WARD H. GOODENOUGHCARYL P. HASKINS

GEOLOGY AND GEOGRAPHY (E)Helmut LandsbergRamon E. BisqueENGINEERING (M)Raynor L. DuncombeC. Towner FrenchINFORMATION ANDCOMMUNICATION MT)

Jordan BaruchScott Adams

DANIEL P. MOYNIHAN WILLIAM T. GOLDENPHYLLIS V. PARKINS Treasurer

BIOLOGICAL SCIENCES (G)Dorothy BlissRichard J. Goss

MEDICAL SCIENCES (N)Robert A. GoodF. Douglas Lawrason

STATISTICS (U) ATMOSPHERFrederick Mosteller SCIENCESEzra Glaser Max A. Koh

Louis J. Bat

WILLIAM BEVANExecutive Officer

ANTHROPOLOGY (H)Richard N. AdamsAnthony Leeds

AGRICULTURE (0)Roy L. LovvornMichael A. Farrell

?IC AND HYDROSPHERIC3 (W)lerittan

The American Association for the Advancement of Science was founded in 1848 and incorporated in1874. Its objects are to further the work of scientists, to facilitate cooperation among them, toitvpme the effectiveness of science in the promotion of human welfare, and to increase public under-standing and appreciation of the importance and promise of the methods of science in human progress.

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COVER

Female crickets are drawn to malesof the same species by the male'scalling song. By placing a tetheredfemale upon a Y-maze and placingloudspeakers on her right and left, herresponsiveness to various songs canbe directly measured (actual size ofcricket, 1 inch in length). See page82. [C. Walcott, Biology Department,State University of New York, StonyBrook]

6 April 1973, Volume 180, Number 4081

AMERICAN ASSOCIATION FORTHE ADVANCEMENT OF SCIENCE

Science serves its readers as a forum for thepresentation and discussion of important issuesrelated to the advancement of science, includingthe presentation of minoritv or conflicting pointsof view, rather than by publishing only materialon which a consensus has been reached. Accord-ingly, all articles published in Science-includingeditorials, news and comment, and book reviews--re signed and reflect the individual views of theauthors and not official points of view adopted bythe AAAS or the institutions with which the authorsare affiliated.

Editorial Board1973

H. S. GUTOWSKYAurHuR D. HASLERRUDOLF KOMPFNERDANIEL E. KOSHLAND, JR.

ALFRED BROWNJAMES F. CROWSEYMOUR S. KETYFRANK PRESS

GARDNER LINDZEYRAYMOND H. THOMPSONEDWARD 0. WILSON

1974FRANK W. PUTNAMMAXINE SINGERGORDON WOLMAN

Editorial StaffEditor

PHILIP H. ABELSONPublisher Business ManagerWILLIAM BEVAN HANS NUSSBAUM

Managing Editor: ROBERT V. ORMES

Assistant Editors: ELLEN E. MURPHY, JOHN E.RINGLE

Assistant to the Editor: NANCY TEIMOURIAN

News and Comment:. JOHN WALSH, LUTIR J.CARTER, DEBORAH SHAPLEY, ROBERT GILLET1E, NICHO-LAS WADE, CONSTANCE HOLDEN, BARBARA J. CULLITON,SCHERRAINE MACK

Research News: ALLEN L. HAMMOND, WILLIAMD. METZ, THOMAS H. MAUGH II, JEAN L. MARX

Book Reviews: SYLVIA EBERHART, KATHERINE LIV-INGSTON, ANN SELTZ-PETRASH

Cover Editor: GRAYCE FINGER

Editorial Assistants: MARGARET ALLEN, ISABELLABOULDIN, BLAIR BURNS; ELEANORE BUTz, MARY DoRP-MAN, JUDITH GIVELBER, CORRINE HARRIS, NANCYHARTNAGEL, OLIVER HEATWOLE, CHRISTINE KARLIK,MARSHALL KATHAN, MARGARET LLOYD, DANIEL RABOV-SKY, JEAN ROCKWOOD, PATRICIA ROWE, LEAH RYAN,JOHN SCHAUER, LoIs SCHMITT, MICHAEL SCHWARTZ,Y.x Li SWIGART

Guide to Scientific Instruments: RICHARD SOMMER

Membership Recruitment: LEONARD WRAY; Subscrip-tions: BErrE SEEMUND; Addressing: THOMAS BAZAN

Advertising StaffDirector Production ManagerEARL J. SCHERAGO PATrY WELLS

Advertising Sales Manager: RICHARD L. CHARLES

Sales: NEW YORK, N.Y. 10036: Herbert L. Burklund,11 W. 42 St. (212-PE-6-1858); SCOTCH PLAINS, N.J.07076: C. Richard Callis, 12 Unami Lane (201-889-4873); CHICAGO, ILL. 60611: John P. Cahill, Room2107, 919 N. Michigan Ave. (312-DE-7-4973); BEv-ERLY HILLS, CALIF. 90211: Winn Nance, 111 N. LaCienega Blvd. (213-657-2772)EDITORIAL CORRESPONDENCE: 1515 Massa-chusetts Ave., NW, Washington, D.C. 20005. Phones:(Area code 202) Central Office: 4674350; Book Re-views: 467-4367; Business Office: 467-4411; Circula-tion: 467-4417; Guide to Scientific Instruments: 467-4480; News and Comment: 4674430; Reprints andPermissions: 467-4483; Research News: 4674321;Reviewing: 467-4440. Cable: Advancesci, Washington.Copies of "Instructions for Contributors" can beobtained from the editorial office. See also page xv,Science, 29 September 1972. ADVERTISING COR-RESPONDENCE: Room 1740, 11 W. 42 St., NewYork, N.Y. 10036. Phone: 212-PE-6-1858.

SCIENCE

Blow-Hot, Blow-Cold Educational Policies

The phasing-out of the training grants and fellowship program at theNational Institutes of Health will sharply curtail the government's directsupport of predoctoral and postdoctoral education in the sciences. Sometraining will continue in connection with research grants, but the num-ber of students supported will be a minor fraction of those who hadreceived stipends earlier. The dismantling of the government's fellowshipprogram liquidates some excesses but, on balance, is a destructive move,and it comes at a time when the need for some kinds of scientists andengineers is actually growing.

After Sputnik was launched, this nation engaged in a frantic effort toexpand its scientific capabilities. For a number of years government fundsavailable for research in the physical and biomedical sciences increasedrapidly. At the same time, the Apollo program was implemented. Thesedevelopments created a shortage of scientists and engineers. The govern-ment responded by initiating and expanding support of many kinds offellowships and training programs. To meet the opportunities of thetimes, uLniversities expanded their faculties, thus increasing opportunitiesfor employment. Industry found it difficult to attract qualified personnel.Demand for scientists seemed insatiable. Help-wanted ads in the NewYork Tiunes and other publications reached record numbers. An indexof employment opportunities, based on such evidence, peaked in 1966at 190 percent of 1961 levels. When government support ceased to grow,demand for scientists began to drop. Universities no longer needed toexpand their faculties, industry began an era of retrenchment. The Apolloprogram entered its final phases. Suddenly there were unemployed scien-tists and engineers, and the index of employment opportunities droppedbelow 40 in 1971. During the peak years, it was common for top-qualitygraduates and Ph.D.'s to receive dozens of job offers. In 1971, the beststudents often had only two or three opportunities, and some graduateshad no jobs for months.The most dramatic unemployment problem was in the aerospace in-

dustry. When activities were cut back, severe local unemployment resulted.A picture of an engineer driving a taxi created a profound and lingeringimpression.Those in government who wished to dismantle the fellowship programs

had a useful excuse. Why train scientists when there were scientistsunemployed? To a substantial extent, the unemployment argument is nolonger valid. The index of employment opportunities has climbed above100. In some regions there already are shortages of engineers.

Influenced by current antitechnology talk and by reports of unemploy-ment, first-year college students have been shunning engineering. Begin-ning enrollment is down more than 30 percent from 2 years ago. Studentsoften leave engineering courses; they rarely enter them after the fresh-man year. Thus, a severe shortage of young engineers may now be pro-jected 4 years hence. This is likely to come at a time when this nationwill be engaged in frantic "crash" programs to solve the energy crisis-an effort that will involve a tremendous construction program and largenumbers of engineers.

In the years ahead, this nation will encounter many unexpected prob-lems requiring the skills of scientists and engineers. We may well cometo regret bitterly the fact that we have been unable to do better thanfollow destructive blow-hot, blow-cold educational policies. We shouldadopt the more realistic assumption that this nation must have goodscience, good medicine, and good engineering, and we should make itpossible for the top students, regardless of financial ability, to participate.

-PHILIP H. ABELSON