7 december 2009 renal physiology lab this week: urinalysis review website for instructions
TRANSCRIPT
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7 December 2009Renal Physiology
Lab this week: Urinalysis
Review website for instructions.
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Abstracts
How to address an unsatisfactory grade: see which sections most points were lost, and concentrate on improving those sections.
Revised abstract due Wednesday Exam Day at 9:00 am.Submit revised abstract, original abstract, original stats report, and 1st Grading rubric all paper-clipped in this order, with revised abstract on top, signed only on the backside.
Overall abstract grade proportion to be determined.
Goal is to master the skill of writing a good abstract.
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Renal Physiology
• Structures of the kidney• Three fundamental renal mechanisms
– Filtration– Reabsorption– Secretion
• Functions of the kidneys– Homeostasis
• Fluid balance (blood pressure)• Electrolyte balance (blood pressure, membrane excitability)• Acid-base balance (in concert with lungs)
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Kidneys are source of 3 hormones: Renin, EPO, and Vit D.Kidneys are targets of 3 hormones: ADH, Aldosterone, ANH
Topics discussed: cortex, medulla, kidney stones, micturition (detrussor, internal and external urethra sphincters and innervation), incidence of bladder infections by gender, urethral sphincters
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Renal artery = One way in. Two ways out of kidney (renal vein or ureter)
Distinction between urine and tubular fluid.
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Fig. 14.04
Cortex and medulla
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Fig. 14.02a
Renalcorpuscle
Juxtamedullary and Cortical Nephrons
Peritubular Capillaraies and branch thereof called vasa recta
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The nephron
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Figure 14.10
Membrane proteins are segregated into apical (luminal) and basolateral membranes.
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Special terms• Filtration: movement of fluid from blood into
the lumen of the nephron
• Reabsorption: the movement of specific compounds from the lumen back into the blood (peritubular capillaries)
• Secretion: the transport of specific compounds from blood into the lumen
• Excretion: elimination from the body in urine
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Fig. 14.03a
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Fig. 14.05Glomerular Filtration Rate is 180 L/day
Three stimuli for secretion of renin from JGC
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Fig. 14.03b
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Figure 14.03Ultrafiltrate of plasma enters Bowman’s space
Composition same as plasma except no formed elements and no proteins
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Fig. 14.08
variable
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Fig. 14.09
Ways to alter GFR
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Fig. 14.06
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Table 14.02
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Lab this week:Extra 800 ml intake!
Sidebar: some desert animals never drink and must obtain all their water in the diet.
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Table 14.04
Lab this week:Extra 7 g intake!
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Figure 14.07
Net Secretion Net Reabsorption
Ex: Sodium
Complete Reabsorption
Ex: Glucose