88210 - gov.uk · 88210 black 213 braille cyan magenta yellow. the enclosed leaflet use. also t s...

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the enclosed leaflet use. Also t s leaflet for fur er information). For oral administration as ec doctor. Store a dry Licence ol r: Cre t Lt , Over , Hants 3ED I f y o u f o r g e t t o t a k e T r i h e x y p h e n i d y l T a b l e t s If you forget to take a dose of this medicine, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the next dose at the usual time. DO NOT TAKE TWO DOSES AT THE SAME TIME. 4 . P O S S I B L E S I D E E F F E C T S 30 – 50% of patients may experience dry mouth, constipation, blurred vision, dizziness and stomach upset. If any of the following occur STOP TAKING the tablets IMMEDIATELY and contact your doctor, as they may be signs of an allergic reaction: shortness of breath, blocked nose, rash, itching, swollen face or lips (could happen to more than 1 in 100 people, but less than 1 in 10) The following other side-effects have been reported with trihexyphenidyl: Uncommon effects (that could happen to more than 1 in 100 people, but less than 1 in 10): difficulty in passing urine faster heart beat nervousness high doses of this medicine may cause excitement, feeling of great happiness, agitation or confusion, hallucinations, restlessness, difficulty sleeping, change in your mental Like all medicines, this medicine can cause side effects, although not everybody gets them. 6 . 5. HOW TO STORE TRIHEXYPHENIDYL TABLETS KEEP ALL MEDICINES OUT OF THE SIGHT AND REACH OF CHILDREN. F U R T H E R I N F O R M A T I O N I n g r e d i e n t s Each Trihexyphenidyl 2mg Tablet contains 2mg of trihexyphenidyl hydrochloride. Other ingredients are magnesium stearate, maize starch, pregelatinised maize starch and lactose. W h a t T r i h e x y p h e n i d y l T a b l e t s l o o k l i k e The tablets are round and white with a breakline on one side. They are available in pack sizes of 28, 30, 42, 50, 56, 60, 84, 90, 100, 112, 250, 500 and 1000 tablets. (Not all pack sizes may be marketed). W h o m a k e s t h i s m e d i c i n e a n d h o l d s t h e P r o d u c t L i c e n c e : The Product Licence Holder is Crescent Pharma Limited, Units 3 & 4, Quidhampton Business Units, Polhampton Lane, Overton, Hampshire, RG25 3ED and the Manufacturer is Surepharm Services Limited, Bretby, Burton Upon Trent, Staffs, DE15 0YZ. Date leaflet revised: June 2015 If you would like this leaflet in a different format, please contact the licence holder at the above address. PL20416/0029 M0190TB x e l m ab s Each tablet contains i yp l The dose will be different for different medical conditions and patients. Your doctor has decided the dose which is best for you. Always follow your doctor’s instructions. The pharmacist’s label will tell you how many tablets to take and how often to take them. If you do not understand anything, ask your doctor or pharmacist. The usual dose starts at 1 – 2mg (half to one 2mg tablet) per day. This may be increased by your doctor gradually to a maximum dose of 20mg (four 5mg tablets) per day. Do not stop taking this medicine suddenly as your symptoms may get worse. If your dose needs to be reduced your doctor will reduce the amount you should take gradually. I f y o u t a k e t o o m a n y T r i h e x y p h e n i d y l T a b l e t s If you think you have taken too many tablets, contact your doctor straight away or go to the nearest hospital casualty department. Take with you any remaining tablets and the pack so that the medicine can be identified. ablets PATIENT INFORMATION LEAFLET TRIHEXYPHENIDYL 2mg Tablets P l e a s e r e a d a l l o f t h i s l e a f l e t c a r e f u l l y b e f o r e y o u s t a r t t a k i n g t h i s m e d i c i n e . K e e p t h e l e a f l e t , y o u m a y n e e d t o r e a d i t a g a i n . I f y o u h a v e a n y q u e s t i o n s o r a r e n o t s u r e a b o u t a n y t h i n g , a s k y o u r d o c t o r o r p h a r m a c i s t . T h i s m e d i c i n e h a s b e e n p r e s c r i b e d f o r y o u . D o n o t p a s s i t o n t o o t h e r s . I t m a y I N T H I S L E A F L E T : 1. What Trihexyphenidyl Tablets are and what they are used for 2. Before you take Trihexyphenidyl Tablets 3. How to take Trihexyphenidyl Tablets 4. Possible side effects 5. How to store Trihexyphenidyl Tablets 6. Further information 1 . W H A T T R I H E X Y P H E N I D Y L T A B L E T S A R E A N D W H A T T H E Y A R E U S E D F O R Trihexyphenidyl belongs to a group of medicines called antimuscarinics (sometimes called anticholinergics). It works by correcting a chemical imbalance in the brain that affects the transmission of nerve impulses. It is used to treat Parkinson’s disease by improving muscle control and reducing stiffness so patients can move more naturally. It is also used to treat abnormal face and body movements, muscle spasms and restlessness caused by certain drugs. 2 . B E F O R E Y O U T A K E T R I H E X Y P H E N I D Y L T A B L E T S D o n o t t a k e t h e s e t a b l e t s i f : you are allergic to trihexyphenidyl hydrochloride or any of the other ingredients in the tablets (see section 6). (An allergic reaction may be recognised as shortness of breath, blocked nose, rash, itching, swollen face or lips). you have an enlarged prostate gland, have bladder problems or have difficulty in passing urine you have glaucoma (increased pressure in the eye) you have a blockage in your stomach or bowel C h e c k w i t h y o u r d o c t o r b e f o r e t a k i n g t h e s e t a b l e t s i f : you have hardening of the arteries you have ever had a reaction to any other medicine you have high blood pressure you have heart, liver or kidney problems you are elder l y you are pregnant or breast feeding. This medicine should you have a condition called myasthenia gravis (a rare muscle weakness disorder) • you experience unusual movements of the face, tongue, arms and legs as this may be a sign of a serious condition known as tardive dyskinesia T a k i n g o t h e r m e d i c i n e s Check with your doctor or pharmacist before taking these tablets if you are taking any other medicines, including any that you can buy without a prescription. This is especially important if you are taking: nefopam (used for pain relief) ketoconazole (used to treat fungal infections) disopyramide (used to treat irregular heart beat) or being sick) amantadine or levodopa (used to treat Parkinson’s disease) monoamine oxidase inhibitors (MAOIs) e.g. isocarboxacid or moclobemide or tri-cyclic antidepressants e.g. amitriptyline (for treating depression) antihistamines (used to treat allergies) • phenothiazines e.g. chlorpromazine (used to treat mental illness) metoclopramide or domperidone (used to stop you feeling any other medicines to help your muscles to contract and which are being used to avoid problems following an operation, such as difficulty passing urine or to treat a condition known as myasthenia gravis (e.g. neostigmine, distigmine) any medicine you have to dissolve under your tongue e.g. glyceryl trinitrate (used to treat angina) any other anti-muscarinic medicines such as those being used to treat irritable bowel syndrome, stomach or bowel darifenacin, oxybutynin) or Parkinson’s disease (e.g. benzatropine, procyclidine). Taking these medicines at the same time may increase the risk of side effects such as dry mouth, difficulty in passing urine and constipation. If you are elderly you may also become confused. Driving or using machinery Some people may experience blurred vision or feel dizzy or less alert than usual when they are taking these tablets. I m p o r t a n t i n f o r m a t i o n a b o u t o n e o f t h e i n g r e d i e n t s o f t h i s m e d i c i n e : Contains lactose. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine. 3 . H O W T O T A K E T R I H E X Y P H E N I D Y L T A B L E T S Swallow the tablets with a drink of water just before or with a meal. NOT be taken during breast feeding. Do not drive or operate machinery if this happens to you. conditions (e.g. atropine, hyoscine), bladder problems (e.g. well-being or you may have paranoid delusions (worry that something bad is happening without any reason). Your memory may also be affected. Reporting of side effects. If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard. By reporting side effects you can help provide more information on the safety of this medicine. Keep the tablets in the pack provided and store in a cool dry place. Do not take the tablets if the expiry date on the pack has passed. harm them, even if their symptoms are the same as yours. If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. See section 4. If you have any medicines that are out of date, return them to your pharmacist for safe disposal.

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the enclosedleaflet use. Also

t s leafletfor fur er information).For oral administration as

ec doctor.

Store a dryLicence ol r:

Cre t Lt ,Over , Hants 3ED

If you forget to take Trihexyphenidyl TabletsIf you forget to take a dose of this medicine, take it as soonas you remember. However, if it is almost time for the nextdose, skip the missed dose and take the next dose at theusual time. DO NOT TAKE TWO DOSES AT THE SAME TIME.4. POSSIBLE SIDE EFFECTS

30 – 50% of patients may experience dry mouth,constipation, blurred vision, dizziness and stomach upset.If any of the following occur STOP TAKING the tabletsIMMEDIATELY and contact your doctor, as they may besigns of an allergic reaction:• shortness of breath, blocked nose, rash, itching, swollen

face or lips (could happen to more than 1 in 100 people,but less than 1 in 10)

The following other side-effects have been reported with

trihexyphenidyl:Uncommon effects (that could happen to more than 1 in100 people, but less than 1 in 10):• difficulty in passing urine• faster heart beat• nervousness• high doses of this medicine may cause excitement, feeling of great happiness, agitation or confusion, hallucinations, restlessness, difficulty sleeping, change in your mental

Like all medicines, this medicine can cause side effects,although not everybody gets them.

6.5. HOW TO STORE TRIHEXYPHENIDYL TABLETSKEEP ALL MEDICINES OUT OF THE SIGHT AND REACH OF CHILDREN.

FURTHER INFORMATIONIngredientsEach Trihexyphenidyl 2mg Tablet contains 2mg oftrihexyphenidyl hydrochloride.Other ingredients are magnesium stearate, maize starch,pregelatinised maize starch and lactose.

What Trihexyphenidyl Tablets look likeThe tablets are round and white with a breakline on one side.They are available in pack sizes of 28, 30, 42, 50, 56, 60, 84,90, 100, 112, 250, 500 and 1000 tablets. (Not all pack sizesmay be marketed).Who makes this medicine and holds the Product Licence:The Product Licence Holder is Crescent Pharma Limited,Units 3 & 4, Quidhampton Business Units, Polhampton Lane,Overton, Hampshire, RG25 3ED and the Manufacturer is

Surepharm Services Limited, Bretby, Burton Upon Trent,Staffs, DE15 0YZ.

Date leaflet revised: June 2015If you would like this leaflet in a different format, pleasecontact the licence holder at the above address.

PL20416/0029M0190TB

x e lmab s

Each tablet containsi yp l

The dose will be different for different medical conditions andpatients. Your doctor has decided the dose which is best foryou. Always follow your doctor’s instructions. Thepharmacist’s label will tell you how many tablets to take andhow often to take them. If you do not understand anything,ask your doctor or pharmacist.The usual dose starts at 1 – 2mg (half to one 2mg tablet) perday. This may be increased by your doctorgradually to a maximum dose of 20mg

(four 5mg tablets) per day.Do not stop taking this medicine suddenly as your symptomsmay get worse. If your dose needs to be reduced your doctorwill reduce the amount you should take gradually.If you take too many Trihexyphenidyl TabletsIf you think you have taken too many tablets, contact yourdoctor straight away or go to the nearest hospital casualtydepartment. Take with you any remaining tablets and the packso that the medicine can be identified.ablets

PATIENT INFORMATION LEAFLETTRIHEXYPHENIDYL 2mg Tablets

Please read all of this leaflet carefully before you starttaking this medicine.Keep the leaflet, you may need to read it again.If you have any questions or are not sure about anything,ask your doctor or pharmacist. This medicine has beenprescribed for you. Do not pass it on to others. It may

IN THIS LEAFLET:1. What Trihexyphenidyl Tablets are and what they are used for2. Before you take Trihexyphenidyl Tablets3. How to take Trihexyphenidyl Tablets

4. Possible side effects5. How to store Trihexyphenidyl Tablets6. Further information1. WHAT TRIHEXYPHENIDYL TABLETS ARE AND

WHAT THEY ARE USED FORTrihexyphenidyl belongs to a group of medicines calledantimuscarinics (sometimes called anticholinergics). Itworks by correcting a chemical imbalance in the brain thataffects the transmission of nerve impulses.

It is used to treat Parkinson’s disease by improving musclecontrol and reducing stiffness so patients can move morenaturally. It is also used to treat abnormal face and bodymovements, muscle spasms and restlessness caused bycertain drugs.2. BEFORE YOU TAKE TRIHEXYPHENIDYL TABLETSDo not take these tablets if:• you are allergic to trihexyphenidyl hydrochloride or any

of the other ingredients in the tablets (see section 6).

(An allergic reaction may be recognised as shortness ofbreath, blocked nose, rash, itching, swollen face or lips).

• you have an enlarged prostate gland, have bladderproblems or have difficulty in passing urine

• you have glaucoma (increased pressure in the eye)• you have a blockage in your stomach or bowel

Check with your doctor before taking these tablets if:• you have hardening of the arteries• you have ever had a reaction to any other medicine• you have high blood pressure• you have heart, liver or kidney problems

• you are elderly

• you are pregnant or breast feeding. This medicine should

• you have a condition called myasthenia gravis (a rare muscle weakness disorder)• you experience unusual movements of the face, tongue, arms and legs as this may be a sign of a serious condition known as tardive dyskinesia

Taking other medicinesCheck with your doctor or pharmacist before taking thesetablets if you are taking any other medicines, including anythat you can buy without a prescription. This is especiallyimportant if you are taking:

• nefopam (used for pain relief)• ketoconazole (used to treat fungal infections)• disopyramide (used to treat irregular heart beat)

or being sick)• amantadine or levodopa (used to treat Parkinson’s disease)• monoamine oxidase inhibitors (MAOIs) e.g. isocarboxacid

or moclobemide or tri-cyclic antidepressants e.g.amitriptyline (for treating depression)

• antihistamines (used to treat allergies)• phenothiazines e.g. chlorpromazine (used to treat mentalillness)

• metoclopramide or domperidone (used to stop you feeling • any other medicines to help your muscles to contract andwhich are being used to avoid problems following anoperation, such as difficulty passing urine or to treat acondition known as myasthenia gravis (e.g. neostigmine,distigmine)

• any medicine you have to dissolve under your tongue e.g.glyceryl trinitrate (used to treat angina)

• any other anti-muscarinic medicines such as those beingused to treat irritable bowel syndrome, stomach or bowel

darifenacin, oxybutynin) or Parkinson’s disease (e.g.benzatropine, procyclidine). Taking these medicines at thesame time may increase the risk of side effects such as drymouth, difficulty in passing urine and constipation. If you areelderly you may also become confused.Driving or using machinerySome people may experience blurred vision or feel dizzy orless alert than usual when they are taking these tablets.

Important information about one of the ingredients of thismedicine:Contains lactose. If you have been told by your doctor that youhave an intolerance to some sugars, contact your doctor beforetaking this medicine.3. HOW TO TAKE TRIHEXYPHENIDYL TABLETSSwallow the tablets with a drink of water just before orwith a meal.

Colour Reference: Black 213

Job No.: 88210Date: 19 June 2015

PROOF 2 100% Label Code M0190TB

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Page Widths: 77 74 73 72 71 70 70 71 72 73 72

Text Size8 pt

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Trihexyphenidyl

TabletsEach tablet containstrihexyphenidylhydrochloride2mg 84 Tablets

NOT be taken during breast feeding. Do not drive or operate machinery if this happens to you.conditions (e.g. atropine, hyoscine), bladder problems (e.g.

well-being or you may have paranoid delusions (worrythat something bad is happening without any reason).Your memory may also be affected.Reporting of side effects.If you get any side effects, talk to your doctor,pharmacist or nurse. This includes any possible sideeffects not listed in this leaflet. You can also report sideeffects directly via the Yellow Card Scheme at

www.mhra.gov.uk/yellowcard. By reporting side effects you canhelp provide more information on the safety of this medicine.

Keep the tablets in the pack provided and store in a cool dryplace.Do not take the tablets if the expiry date on the pack haspassed.

harm them, even if their symptoms are the same as yours.If you get any side effects, talk to your doctor, pharmacistor nurse. This includes any possible side effects not listedin this leaflet. See section 4.

If you have any medicines that are out of date, return themto your pharmacist for safe disposal.

88210

Black 213 Braille Cyan Magenta Yellow

the enclosedleaflet use. Also

t s leafletfor fur er information).For oral administration as

ec doctor.

Store a dryLicence ol r:

Cre t Lt ,Over , Hants 3ED

If you forget to take Trihexyphenidyl TabletsIf you forget to take a dose of this medicine, take it as soonas you remember. However, if it is almost time for the nextdose, skip the missed dose and take the next dose at theusual time. DO NOT TAKE TWO DOSES AT THE SAME TIME.4. POSSIBLE SIDE EFFECTS

30 – 50% of patients may experience dry mouth,constipation, blurred vision, dizziness and stomach upset.If any of the following occur STOP TAKING the tabletsIMMEDIATELY and contact your doctor, as they may besigns of an allergic reaction:• shortness of breath, blocked nose, rash, itching, swollen

face or lips (could happen to more than 1 in 100 people,but less than 1 in 10)

The following other side-effects have been reported with

trihexyphenidyl:Uncommon effects (that could happen to more than 1 in100 people, but less than 1 in 10):• difficulty in passing urine• faster heart beat• nervousness• high doses of this medicine may cause excitement, feeling of great happiness, agitation or confusion, hallucinations, restlessness, difficulty sleeping, change in your mental

Like all medicines, this medicine can cause side effects,although not everybody gets them.

6.5. HOW TO STORE TRIHEXYPHENIDYL TABLETSKEEP ALL MEDICINES OUT OF THE SIGHT AND REACH OF CHILDREN.

FURTHER INFORMATIONIngredientsEach Trihexyphenidyl 2mg Tablet contains 2mg oftrihexyphenidyl hydrochloride.Other ingredients are magnesium stearate, maize starch,pregelatinised maize starch and lactose.

What Trihexyphenidyl Tablets look likeThe tablets are round and white with a breakline on one side.They are available in pack sizes of 28, 30, 42, 50, 56, 60, 84,90, 100, 112, 250, 500 and 1000 tablets. (Not all pack sizesmay be marketed).Who makes this medicine and holds the Product Licence:The Product Licence Holder is Crescent Pharma Limited,Units 3 & 4, Quidhampton Business Units, Polhampton Lane,Overton, Hampshire, RG25 3ED and the Manufacturer is

Surepharm Services Limited, Bretby, Burton Upon Trent,Staffs, DE15 0YZ.

Date leaflet revised: June 2015If you would like this leaflet in a different format, pleasecontact the licence holder at the above address.

PL20416/0029M0190TB

x e lmab s

Each tablet containsi yp l

The dose will be different for different medical conditions andpatients. Your doctor has decided the dose which is best foryou. Always follow your doctor’s instructions. Thepharmacist’s label will tell you how many tablets to take andhow often to take them. If you do not understand anything,ask your doctor or pharmacist.The usual dose starts at 1 – 2mg (half to one 2mg tablet) perday. This may be increased by your doctorgradually to a maximum dose of 20mg

(four 5mg tablets) per day.Do not stop taking this medicine suddenly as your symptomsmay get worse. If your dose needs to be reduced your doctorwill reduce the amount you should take gradually.If you take too many Trihexyphenidyl TabletsIf you think you have taken too many tablets, contact yourdoctor straight away or go to the nearest hospital casualtydepartment. Take with you any remaining tablets and the packso that the medicine can be identified.ablets

PATIENT INFORMATION LEAFLETTRIHEXYPHENIDYL 2mg Tablets

Please read all of this leaflet carefully before you starttaking this medicine.Keep the leaflet, you may need to read it again.If you have any questions or are not sure about anything,ask your doctor or pharmacist. This medicine has beenprescribed for you. Do not pass it on to others. It may

IN THIS LEAFLET:1. What Trihexyphenidyl Tablets are and what they are used for2. Before you take Trihexyphenidyl Tablets3. How to take Trihexyphenidyl Tablets

4. Possible side effects5. How to store Trihexyphenidyl Tablets6. Further information1. WHAT TRIHEXYPHENIDYL TABLETS ARE AND

WHAT THEY ARE USED FORTrihexyphenidyl belongs to a group of medicines calledantimuscarinics (sometimes called anticholinergics). Itworks by correcting a chemical imbalance in the brain thataffects the transmission of nerve impulses.

It is used to treat Parkinson’s disease by improving musclecontrol and reducing stiffness so patients can move morenaturally. It is also used to treat abnormal face and bodymovements, muscle spasms and restlessness caused bycertain drugs.2. BEFORE YOU TAKE TRIHEXYPHENIDYL TABLETSDo not take these tablets if:• you are allergic to trihexyphenidyl hydrochloride or any

of the other ingredients in the tablets (see section 6).

(An allergic reaction may be recognised as shortness ofbreath, blocked nose, rash, itching, swollen face or lips).

• you have an enlarged prostate gland, have bladderproblems or have difficulty in passing urine

• you have glaucoma (increased pressure in the eye)• you have a blockage in your stomach or bowel

Check with your doctor before taking these tablets if:• you have hardening of the arteries• you have ever had a reaction to any other medicine• you have high blood pressure• you have heart, liver or kidney problems

• you are elderly

• you are pregnant or breast feeding. This medicine should

• you have a condition called myasthenia gravis (a rare muscle weakness disorder)• you experience unusual movements of the face, tongue, arms and legs as this may be a sign of a serious condition known as tardive dyskinesia

Taking other medicinesCheck with your doctor or pharmacist before taking thesetablets if you are taking any other medicines, including anythat you can buy without a prescription. This is especiallyimportant if you are taking:

• nefopam (used for pain relief)• ketoconazole (used to treat fungal infections)• disopyramide (used to treat irregular heart beat)

or being sick)• amantadine or levodopa (used to treat Parkinson’s disease)• monoamine oxidase inhibitors (MAOIs) e.g. isocarboxacid

or moclobemide or tri-cyclic antidepressants e.g.amitriptyline (for treating depression)

• antihistamines (used to treat allergies)• phenothiazines e.g. chlorpromazine (used to treat mentalillness)

• metoclopramide or domperidone (used to stop you feeling • any other medicines to help your muscles to contract andwhich are being used to avoid problems following anoperation, such as difficulty passing urine or to treat acondition known as myasthenia gravis (e.g. neostigmine,distigmine)

• any medicine you have to dissolve under your tongue e.g.glyceryl trinitrate (used to treat angina)

• any other anti-muscarinic medicines such as those beingused to treat irritable bowel syndrome, stomach or bowel

darifenacin, oxybutynin) or Parkinson’s disease (e.g.benzatropine, procyclidine). Taking these medicines at thesame time may increase the risk of side effects such as drymouth, difficulty in passing urine and constipation. If you areelderly you may also become confused.Driving or using machinerySome people may experience blurred vision or feel dizzy orless alert than usual when they are taking these tablets.

Important information about one of the ingredients of thismedicine:Contains lactose. If you have been told by your doctor that youhave an intolerance to some sugars, contact your doctor beforetaking this medicine.3. HOW TO TAKE TRIHEXYPHENIDYL TABLETSSwallow the tablets with a drink of water just before orwith a meal.

Colour Reference: Black 213

Job No.: 88210Date: 19 June 2015

PROOF 2 100% Label Code M0190TB

Pee

lher

eto

open

but

dono

tre

mov

e

Cre

scen

tPha

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Lim

ited,

Uni

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Busi

ness

Uni

ts,P

olha

mpt

onLa

ne,

Ove

rton,

Ham

pshi

reR

G25

3ED

Base Label: 30 x 100mm

Leaflet Page 1: 30 x 77mm

Left Hand Opening

Overall Leaflet Size: 30 x 795

Page Widths: 77 74 73 72 71 70 70 71 72 73 72

Text Size8 pt

Bat

chN

o.:

Exp

iryD

ate:

M01

90T

B

Trihexyphenidyl

TabletsEach tablet containstrihexyphenidylhydrochloride2mg 84 Tablets

NOT be taken during breast feeding. Do not drive or operate machinery if this happens to you.conditions (e.g. atropine, hyoscine), bladder problems (e.g.

well-being or you may have paranoid delusions (worrythat something bad is happening without any reason).Your memory may also be affected.Reporting of side effects.If you get any side effects, talk to your doctor,pharmacist or nurse. This includes any possible sideeffects not listed in this leaflet. You can also report sideeffects directly via the Yellow Card Scheme at

www.mhra.gov.uk/yellowcard. By reporting side effects you canhelp provide more information on the safety of this medicine.

Keep the tablets in the pack provided and store in a cool dryplace.Do not take the tablets if the expiry date on the pack haspassed.

harm them, even if their symptoms are the same as yours.If you get any side effects, talk to your doctor, pharmacistor nurse. This includes any possible side effects not listedin this leaflet. See section 4.

If you have any medicines that are out of date, return themto your pharmacist for safe disposal.

88210

Black 213 Braille Cyan Magenta Yellow

the enclosedleaflet use. Also

t s leafletfor fur er information).For oral administration as

ec doctor.

Store a dryLicence ol r:

Cre t Lt ,Over , Hants 3ED

If you forget to take Trihexyphenidyl TabletsIf you forget to take a dose of this medicine, take it as soonas you remember. However, if it is almost time for the nextdose, skip the missed dose and take the next dose at theusual time. DO NOT TAKE TWO DOSES AT THE SAME TIME.4. POSSIBLE SIDE EFFECTS

30 – 50% of patients may experience dry mouth,constipation, blurred vision, dizziness and stomach upset.If any of the following occur STOP TAKING the tabletsIMMEDIATELY and contact your doctor, as they may besigns of an allergic reaction:• shortness of breath, blocked nose, rash, itching, swollen

face or lips (could happen to more than 1 in 100 people,but less than 1 in 10)

The following other side-effects have been reported with

trihexyphenidyl:Uncommon effects (that could happen to more than 1 in100 people, but less than 1 in 10):• difficulty in passing urine• faster heart beat• nervousness• high doses of this medicine may cause excitement, feeling of great happiness, agitation or confusion, hallucinations, restlessness, difficulty sleeping, change in your mental

Like all medicines, this medicine can cause side effects,although not everybody gets them.

6.5. HOW TO STORE TRIHEXYPHENIDYL TABLETSKEEP ALL MEDICINES OUT OF THE SIGHT AND REACH OF CHILDREN.

FURTHER INFORMATIONIngredientsEach Trihexyphenidyl 2mg Tablet contains 2mg oftrihexyphenidyl hydrochloride.Other ingredients are magnesium stearate, maize starch,pregelatinised maize starch and lactose.

What Trihexyphenidyl Tablets look likeThe tablets are round and white with a breakline on one side.They are available in pack sizes of 28, 30, 42, 50, 56, 60, 84,90, 100, 112, 250, 500 and 1000 tablets. (Not all pack sizesmay be marketed).Who makes this medicine and holds the Product Licence:The Product Licence Holder is Crescent Pharma Limited,Units 3 & 4, Quidhampton Business Units, Polhampton Lane,Overton, Hampshire, RG25 3ED and the Manufacturer is

Surepharm Services Limited, Bretby, Burton Upon Trent,Staffs, DE15 0YZ.

Date leaflet revised: June 2015If you would like this leaflet in a different format, pleasecontact the licence holder at the above address.

PL20416/0029M0190TB

x e lmab s

Each tablet containsi yp l

The dose will be different for different medical conditions andpatients. Your doctor has decided the dose which is best foryou. Always follow your doctor’s instructions. Thepharmacist’s label will tell you how many tablets to take andhow often to take them. If you do not understand anything,ask your doctor or pharmacist.The usual dose starts at 1 – 2mg (half to one 2mg tablet) perday. This may be increased by your doctorgradually to a maximum dose of 20mg

(four 5mg tablets) per day.Do not stop taking this medicine suddenly as your symptomsmay get worse. If your dose needs to be reduced your doctorwill reduce the amount you should take gradually.If you take too many Trihexyphenidyl TabletsIf you think you have taken too many tablets, contact yourdoctor straight away or go to the nearest hospital casualtydepartment. Take with you any remaining tablets and the packso that the medicine can be identified.ablets

PATIENT INFORMATION LEAFLETTRIHEXYPHENIDYL 2mg Tablets

Please read all of this leaflet carefully before you starttaking this medicine.Keep the leaflet, you may need to read it again.If you have any questions or are not sure about anything,ask your doctor or pharmacist. This medicine has beenprescribed for you. Do not pass it on to others. It may

IN THIS LEAFLET:1. What Trihexyphenidyl Tablets are and what they are used for2. Before you take Trihexyphenidyl Tablets3. How to take Trihexyphenidyl Tablets

4. Possible side effects5. How to store Trihexyphenidyl Tablets6. Further information1. WHAT TRIHEXYPHENIDYL TABLETS ARE AND

WHAT THEY ARE USED FORTrihexyphenidyl belongs to a group of medicines calledantimuscarinics (sometimes called anticholinergics). Itworks by correcting a chemical imbalance in the brain thataffects the transmission of nerve impulses.

It is used to treat Parkinson’s disease by improving musclecontrol and reducing stiffness so patients can move morenaturally. It is also used to treat abnormal face and bodymovements, muscle spasms and restlessness caused bycertain drugs.2. BEFORE YOU TAKE TRIHEXYPHENIDYL TABLETSDo not take these tablets if:• you are allergic to trihexyphenidyl hydrochloride or any

of the other ingredients in the tablets (see section 6).

(An allergic reaction may be recognised as shortness ofbreath, blocked nose, rash, itching, swollen face or lips).

• you have an enlarged prostate gland, have bladderproblems or have difficulty in passing urine

• you have glaucoma (increased pressure in the eye)• you have a blockage in your stomach or bowel

Check with your doctor before taking these tablets if:• you have hardening of the arteries• you have ever had a reaction to any other medicine• you have high blood pressure• you have heart, liver or kidney problems

• you are elderly

• you are pregnant or breast feeding. This medicine should

• you have a condition called myasthenia gravis (a rare muscle weakness disorder)• you experience unusual movements of the face, tongue, arms and legs as this may be a sign of a serious condition known as tardive dyskinesia

Taking other medicinesCheck with your doctor or pharmacist before taking thesetablets if you are taking any other medicines, including anythat you can buy without a prescription. This is especiallyimportant if you are taking:

• nefopam (used for pain relief)• ketoconazole (used to treat fungal infections)• disopyramide (used to treat irregular heart beat)

or being sick)• amantadine or levodopa (used to treat Parkinson’s disease)• monoamine oxidase inhibitors (MAOIs) e.g. isocarboxacid

or moclobemide or tri-cyclic antidepressants e.g.amitriptyline (for treating depression)

• antihistamines (used to treat allergies)• phenothiazines e.g. chlorpromazine (used to treat mentalillness)

• metoclopramide or domperidone (used to stop you feeling • any other medicines to help your muscles to contract andwhich are being used to avoid problems following anoperation, such as difficulty passing urine or to treat acondition known as myasthenia gravis (e.g. neostigmine,distigmine)

• any medicine you have to dissolve under your tongue e.g.glyceryl trinitrate (used to treat angina)

• any other anti-muscarinic medicines such as those beingused to treat irritable bowel syndrome, stomach or bowel

darifenacin, oxybutynin) or Parkinson’s disease (e.g.benzatropine, procyclidine). Taking these medicines at thesame time may increase the risk of side effects such as drymouth, difficulty in passing urine and constipation. If you areelderly you may also become confused.Driving or using machinerySome people may experience blurred vision or feel dizzy orless alert than usual when they are taking these tablets.

Important information about one of the ingredients of thismedicine:Contains lactose. If you have been told by your doctor that youhave an intolerance to some sugars, contact your doctor beforetaking this medicine.3. HOW TO TAKE TRIHEXYPHENIDYL TABLETSSwallow the tablets with a drink of water just before orwith a meal.

Colour Reference: Black 213

Job No.: 88210Date: 19 June 2015

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Trihexyphenidyl

TabletsEach tablet containstrihexyphenidylhydrochloride2mg 84 Tablets

NOT be taken during breast feeding. Do not drive or operate machinery if this happens to you.conditions (e.g. atropine, hyoscine), bladder problems (e.g.

well-being or you may have paranoid delusions (worrythat something bad is happening without any reason).Your memory may also be affected.Reporting of side effects.If you get any side effects, talk to your doctor,pharmacist or nurse. This includes any possible sideeffects not listed in this leaflet. You can also report sideeffects directly via the Yellow Card Scheme at

www.mhra.gov.uk/yellowcard. By reporting side effects you canhelp provide more information on the safety of this medicine.

Keep the tablets in the pack provided and store in a cool dryplace.Do not take the tablets if the expiry date on the pack haspassed.

harm them, even if their symptoms are the same as yours.If you get any side effects, talk to your doctor, pharmacistor nurse. This includes any possible side effects not listedin this leaflet. See section 4.

If you have any medicines that are out of date, return themto your pharmacist for safe disposal.

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