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A service provided to medicine by
Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License
Pharmacokinetics
A service provided to medicine by
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Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License
Oral administration
Blood concentration afteroral administration
Blood concentration afterrepeated oral administration
Time
Con
cent
ratio
n
Cmax
tmax
TimeC
once
ntra
tion
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Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License
IV administration
Blood concentrationduring a perfusion
Blood concentration duringa repeated intravenously
administration
TimeC
once
ntra
tion
Time
Con
cent
ratio
n
Accumulationphase
Equilibriumphase
Decreasephase
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Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License
Pluriexponential decreaseof plasmatic concentration
Time
Con
cent
ratio
n
TimeC
once
ntra
tion
Exponential decrease ofplasmatic concentraion
C0
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Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License
Dose/effect link
Normal people
Plasmatic concentration
Eff
ect
inte
nsity
Therapeutic effectSide effects
Time
Con
cent
ratio
n
Time
Con
cent
ratio
n
People suffering fromrenal insufficiency
Emax
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Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License
Blood concentration with and without enterohepatic recycling
Time
Con
cent
ratio
nWith enterohepaticrecycling
Without enterohepaticrecycling
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Gauss curve