a small dose of toxicologywelcome to large dose of toxicology paracelsus paracelsus was so grandiose...

A Small Dose of Toxicology Welcome to Large Dose of Toxicology

ParacelsusParacelsus was so grandiose

And perhaps just a little bit grossManure, blood, and sandand thus you create man

But what makes it a poison is dose!

The Undecided DoseToo much of a thing makes you blue

But not having it can kill you tooToo much or too littleLet's not be so fickle

We'll go Dutch and divide it by two.

Limericks by Toni Hayes


A Larger Dose of Toxicology

Welcome !!

Introduction to the Health Effects of Chemicals

Steven G. Gilbert, PhD, DABT

www.asmalldoseof.orgwww.toxipedia.org

2010 Northwest Hazardous Materials Management Conference

June 10, 2010

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Large Dose of Toxicology

Objective

Increase our understanding of how chemicals affect human health.


8:00 Overview to “A Larger Dose of Toxicology”

8:30 Non-Cancer and Neurotoxicology

9:30 Break

9:50 Case Study: Health Effects of Lead

11:00 Precautionary Assessment – Beyond RA

11:45 Questions and Answers

12:00 Adjourn

A Large Dose of Toxicology


A Small Dose of Toxicology

See: www.asmalldoseof.org -- smdose


Small Dose of Toxicology


Milestones of Toxicology


www.toxipedia.org

A free toxicology encyclopedia and resource center that anyone can edit. Toxipedia provides comprehensive, accurate, and scientifically based information on the hazards and risks of chemical and physical agents, with the goal of advancing human and environmental health. Toxipedia


The World Library of Toxicology


Toxipedia suite of sites

www.ipmopedia.org

www.healthyworldtheater.orgwww.wanmec.org

www.toxipedia.org

www.wltox.org

A Small Dose of Toxicology Welcome to Small Dose of ToxicologyWelcome to Large Dose of Toxicologywww.wltox.org


Connecting Gardeners and Experts for Green Gardening Solutions Identify Your Pest

Find the Right Plant Ask the Experts Garden Design Guide Indoor Pest Control

www.ipmopedia.org

Supported by Local Hazardous Waste Management Program in King County, WA.


14


Healthy World Theater• http://healthyworldtheater.org

• promote awareness and understanding through the arts to create a more healthy and peaceful world

• plays, poems, jokes, fiction, music, cartoons, haiku, and even limericks


16


Washington Nuclear Museum and Educational Center (WANMEC)

• http://wanmec.org

• learning from the past for a safer tomorrow

• a project of Washington Physicians for Social Responsibility - funded in part by WA DOE


Toxipedia www.toxipedia.org

Connecting Science and People

Washington Nuclear Museum and Education Center - www.wanmec.org

Integrate Pest Managementwww.IPMopedia.org

World Library of Toxicology www.wltox.org

Healthy World Theaterwww.healthyworldtheater.org

A product of the Institute of Neurotoxicology and Neurological Disorders (INND) For more information contact Steven G. Gilbert at [email protected]

Connecting Gardeners and Experts for Green Gardening Solutions

Learning from the past for a safer tomorrow Uniting art and science for a healthy, peaceful world

Connecting Scientists and Experts to Improve Global Health


Creating websites and communication tools for the scientific and nonprofit community

Putting scientific information in the context of history, society, and culture

Toxipedia Web Development Services


LDDI Consensus Statement

Scientific Consensus Statement on Environmental Agents Associated with

Neurodevelopmental DisordersDeveloped by the Collaborative on

Health and the Environment’s Learning and Developmental Disabilities

InitiativeNovember 7, 2007

http://www.iceh.org/LDDI.html


LDDI Consensus Statement

http://www.iceh.org/LDDI.html

Given the established knowledge, protecting children from neurotoxic environmental exposures from the earliest stages of fetal development clearly is an essential public health measure if we are to help prevent learning and developmental disorders and create an environment in which children can reach and maintain their full potential.


NW Public Health

See: http://healthlinks.washington.edu/nwcphp/nph/

nwph

Public Health and the Precautionary

Principle

By Steven G. Gilbert


Precautionary Principle

“When an activity raises threats of harm to human health or the environment,

precautionary measures should be take even if some cause and effect relationships are not

fully established scientifically.”

Wingspread Conference, 1998.


Child Health


So Many Chemicals so Little Data

2863 above 1 Million pounds

78.2% no data

21.4% some data

12 or 0.4% good data

www.preventingharm.org


Nearly 12 million children (17%) under age 18 in the US suffer from one or more developmental disabilities

Learning disabilities – 5-10% of kids in public school

ADHD – 3-6% of all school kids, maybe higher

The Consequences


Key Words of Toxicology

Hazard X Exposure = Risk

Individual Susceptibility

Dose / Response


A Small Dose of – web site

A Small Dose of Toxicology

www.asmalldoseof.org


A Larger Dose of Toxicology

a small dose of toxicologywelcome to large dose of toxicology paracelsus paracelsus was so grandiose...

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