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Academic Health Science Centres engines of innovation or re-inventing the wheel?

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Page 1: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Academic Health Science Centres –

engines of innovation or re-inventing the wheel?

Page 2: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

The challenges confronting the UK healthcare system:

• Improving service quality while reducing costs

• Redesign of patient pathways

• Shifting emphasis from treatment to prevention

• Accelerating the translation of discovery into patient benefit

Page 3: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Universities and their hospital partners risk being driven apart by:

• the target and management culture of the NHS

• the RAE’s emphasis on basic science

• imminent financial pressures

Page 4: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Universities and their hospital partners risk being driven apart by:

• the target and management culture of the NHS

• the RAE’s emphasis on basic science

• imminent financial pressures

Page 5: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

An Academic Health Sciences Centre at the heart of a world cityProfessor Robert Lechler

Page 6: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Page 5

The partners –four highly-performing institutions Page 5

Hillingdon

Harrow

Ealing

Brent

Barnet

Enfield

Haringey

Camden

Hounslow

Richmond Wandsworth

Kingston

Merton

Sutton Croydon

Bromley

Lewisham

Lambeth

Southwark

Greenwich

WestminsterKen.

& Chel.

CityTowerHamlets

Newham

HackneyIslington

Waltham Forest

Redbridge

Havering

Barking

Bexley

Guy’s and St. Thomas’

South London and the Maudsley King’s College Hospital

Page 7: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Page 6

Our vision –a radical change in healthcare Page 6

King’s Health Partners is pioneering better health and well-being, locally and globally, through integrating excellence…

in research in education/training in patient care

Page 8: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Page 7

The vision –a radical change in healthcare

To advance health and well-being by integrating world-class research, care, education and training through:

• Developing a workforce that will transform healthcare – deliveringinnovation through education

• Integrating physical and mental healthcare to deliver a holistic approach to patient care

• Translating research more rapidly into clinical practice and effectively disseminating these advances through education and training

• Harnessing the power of discovery science to transform the nature of healthcare by moving from treatment towards population screening and disease prevention

Page 9: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Page 8

The vision –a radical change in healthcare

To advance health and well-being by integrating world-class research, care, education and training through:

• Developing a workforce that will transform healthcare – deliveringinnovation through education

• Integrating physical and mental healthcare to deliver a holistic approach to patient care

• Translating research more rapidly into clinical practice and effectively disseminating these advances through education and training

• Harnessing the power of discovery science to transform the nature of healthcare by moving from treatment towards population screening and disease prevention

Page 10: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Partnership Board

King’s Health Partners Executive

Infrastructure to supportExperimental medicine

Efficient infrastructure to deliver translation

Basic SciencesInstitute

Drive basic discovery

NIHR BiomedicalResearch Centres Drive translation

Health Policy and EvaluationInstitute Evaluate

Clinical Academic Groups: key to accelerating translation

CardiovascularDementia and Older People’s Mental Health

Diabetesand

Obesity

Other Clinical Academic

Groups

CLINICAL ACADEMIC GROUPS

Disorder / Research Based Training and EducationEDUCATION ACADEMY

Disorder- / Research-based training and education

Disseminate knowledge,train the next generation

KCL GSTT KCH SLaM

Page 9

Page 11: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Page 10Page 10CAG and Research Group Structure

Health Policy and Evaluation Institute

4. Clinical Neurosciences

12. Child Health

14. Allergy, Respiratory, Critical care

& Anaesthetics

8. Diabetes, Nutrition, Endocrine

Obesity & Ophthalmology

1. Liver, Renal, Urology,Transplant

& Gastro/GI Surgery

11. Women’s

5. Cancer,Haematology, Palliative Care& Therapies

6. Dental

9. Genetics, Rheumatology

Infection, Dermatology

3. Cardio-Vascular

7. Medicine 10. Imaging

13. PharmaceuticalSciences

2. Orthopaedics, Trauma, ENT &

plastics

15. Mental Healthof Older Adults

& Dementia

21. PsychologicalMedical

20. Mood, Anxiety & Personality

Disorder

19. Behavioural &Developmental

Psychiatry

18. Psychosis17. Addictions16. Child &Adolescent

Mental Health

Basic Science Institute

Page 12: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

KHP Research Committee

Basic Science Executive Experimental Medicinecommittee HPE Executive

KHP Executive KCL Research Committee

Research management Page 11

Page 13: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Page 12

We are creating a platform to support experimental medicine across all three campuses

• State-of-the-art facilities are essential to facilitate Experimental Medicine

• Within King’s Health Partners there is an extensive and growing range of core research facilities and underlying technical skills to support innovation and its rapid translation to care for patients

• Clinical Research Facilities are being tailored to each of our hospital sites:

• We have established a Joint Clinical Trials Office (JCTO) dedicated to overseeing the management of commercial trials

Site Focus Co-funder On Stream

St Thomas’ Cardiovascular, Nutritional, Metabolic & Related studies

GSTT Charity, NIHR BRC, Tate & Lyle plc

Opened 2008

Denmark Hill Neuroscience & psychiatric studies inc. PET & MRI facilities and cell therapy

Wellcome Trust Late 2010

Guy’s Asthma, Allergy & Immunology with a GMP cell therapy suite

GSTT CharityNIHR BRC

Opened May 2010

Page 14: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Page 13Guy’s Tower Experimental Medicine Hub

Floor 16: comprehensive DH Biomedical Research Centre /JCTO

Floor 15: CRF, the Joint Clinical Trials Office

Floor 14: Phase 1 unit with Quintiles

Floor 13: GMP manufacturing facility, operated by GSTFT and available for formulation of NCEs

Floor 11: GMP suite attached to Assisted conception unit for ES lines

Page 15: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney
Page 16: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Page 15

The vision –a radical change in healthcare

To advance health and well-being by integrating world-class research, care, education and training through:

• Developing a workforce that will transform healthcare – deliveringinnovation through education

• Integrating physical and mental healthcare to deliver a holistic approach to patient care

• Translating research more rapidly into clinical practice and effectively disseminating these advances through education and training

• Harnessing the power of discovery science to transform the nature of healthcare by moving from treatment towards population screening and disease prevention

Page 18: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Mental health in general hospitals

Cognitive impairments

Delirium and dementia

Mental capacity

Coping and adjusting to disease

Comorbid depression and anxiety

A&E Emergency psychiatry

Substance misuse

Physical disease in people with established mental

disorders

Medically unexplained symptoms

Major incidents and trauma

Perinatal disorders

Health related behaviours:

• primary prevention

• Secondary prevention

Mental health in general hospitals Page 17

Page 19: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

• Chronic fatigue syndrome

• Viral hepatitis

• Anxiety in cancer

• Secondary prevention in diabetes

Some examples Page 18

Page 20: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Page 19Integrating physical and mental health care

• Psychological Medicine CAG

• Aim to screen all patients admitted to acute Trustsfor depression

• Target appropriate interventions

Page 21: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Page 20

The vision –a radical change in healthcare

To advance health and well-being by integrating world-class research, care, education and training through:

• Developing a workforce that will transform healthcare – deliveringinnovation through education

• Integrating physical and mental healthcare to deliver a holistic approach to patient care

• Translating research more rapidly into clinical practice and effectively disseminating these advances through education and training

• Harnessing the power of discovery science to transform the nature of healthcare by moving from treatment towards population screening and disease prevention

Page 22: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

From treatment towards the promotion of health

Source : Department of Health Community Health Profiles 2009

KeyWorse than London average

In line with London average

Better than London average

Health Indicator Lambeth Southwark Lewisham Greenwich Croydon Bromley Bexley

Binge drinking adults

Deaths from smoking

Drug Misuse

Early deaths: Cancer

Early deaths: Heart disease& stroke

Healthy eating adults

Hospital stays due to alcohol

Infant Mortality

Life expectancy

Mental Illness

Obese Adults

Obese Children

Physically active adults

Teenage Pregnancy

Tuberculosis

Violent Crime

Page 21

Page 23: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Page 22Integrating community services

• Competed successfully for the community services of Lambeth and Southwark

• Adds a further £100m business to our partnership

• Should facilitate pathway redesign and shift of activity out of hospital

Page 24: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Page 23Integrated care pilot

Patient

•Assessment

GP•Triage•Treat•Monitor

Physiotherapist assessment

•Surgical assessment

Orthopaedic Surgeon

Pre-operative assessment

• Operation• Recovery• Social/home assessment• Home equipment package

Hospital Stay 8-11 days •Community and

Social Care support

Pack age to home

Speeding up the Patient Pathway – example of an elderly orthopaedic patient

Current Patient Pathway (6 Steps)

Patient

•Assessment

GP• Physiotherapy assessment• Surgical and pre-operative assessments• Social/home care designed and assembled

Integrated Assessment

•Operation•Recovery

Hospital Stay 3-5 days

•Community and Social Care support

Pack age to home

Potential Patient Pathway (4 Steps)

Page 25: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

The new public health….

• Bringing social scientists, ethicists, geneticists, epidemiologists, behavioural psychologists, and primary care practitioners together to address health inequalities and promote prevention

• Aim is to stratify risk in healthy populations and target early interventions

• Each Clinical Academic Group will be required to develop plans for community based prevention in their strategy.

Page 24

Page 26: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Page 25

The vision –a radical change in healthcare

To advance health and well-being by integrating world-class research, care, education and training through:

• Developing a workforce that will transform healthcare – deliveringinnovation through education

• Integrating physical and mental healthcare to deliver a holistic approach to patient care

• Translating research more rapidly into clinical practice and effectively disseminating these advances through education and training

• Harnessing the power of discovery science to transform the nature of healthcare by moving from treatment towards population screening and disease prevention

Page 27: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Quality assurance

Innovative technology & teaching

Widening participation

Global health education & training

Leadership

Postgraduate clinical education

Careers management

Simulation

Pedagogic research

Improving health and well-being

Research & teaching

IPE & IPT

Education Academy Page 26

Men

tal H

ealth

of O

lder

Adu

lts a

nd

Dem

entia

Dia

bete

s, N

utrit

ion,

End

ocrin

e, O

besi

ty

& O

phth

alm

olog

y

Pha

rmac

eutic

al S

cien

ces

Can

cer,

Hae

mat

olog

y &

Pal

liativ

e C

are

Car

diov

ascu

lar

Clinical Academic Groups (CAGs)

Page 28: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Page 27Our Simulation Programme• Brand new Simulation Centre

• Using latest technology - computer controlled human patient manikins that breathe, have a pulse, can blink and speak.

• Trainees can assess and treat a ‘living’ manikin in a realistic ward environment, operating theatre or intensive care unit.

• First hospital simulation centre to include GP surgery and home environments.

Page 29: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Clusters Page 28

Page 30: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

London’s riches

• Almost 45% of all postgraduate students undertaking medicine and dentistry are based in London.

• 49% total research funding in Clinical Medicine and Dentistry

• Almost 33% of undergraduate medicine and dentistry students are based in London higher education institutions

Page 29

• Three Health Innovation and Education Clusters

• Three of the world’s top 25 Universities (Times Higher)

• Three of five AHSCs

• Three of five comprehensive Biomedical Research Centres

Page 31: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Three AHSCs working together to make London a/the world-leading healthcare city

• neuroscience

• PET imaging and radiochemistry

• e-health and informatics

London’s riches Page 30

Page 32: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Re-inventing the wheel….?

Page 33: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Contrast with Hammersmith Hospital of the 1970s & 1980s

• Balanced emphasis on service quality, research & education

• Commitment to vertical integration of healthcare

• Commitment to prevention and public health

Page 34: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

The challenges confronting the healthcare system:

• Improving service quality while reducing costs

• Redesign of patient pathways

• Shifting emphasis from treatment to prevention

• Accelerating the translation of discovery into patient benefit

Addressing these challenges is at the heart of the AHSC agenda

Page 35: Academic Health Science Centres - King's Fund · Merton Sutton Croydon Bromley Lewisham Lambeth Southwark Greenwich Westminster Ken. & Chel. City Tower Hamlets Newham IslingtonHackney

Thank you!