acb yogurt dermal respiratory factor pf · acb yogurt dermal respiratory factor pf. ... ideal for...
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ACB Yogurt Dermal Respiratory Factor PF
Tomorrow’s Vision… Today!®
Cellular Respiration + Collagen Production + Probiotic + Soothing + ATP Synthesis
Product Code: 20224PF
INCI Name: Lactobacillus Ferment Lysate Filtrate
INCI Status: Conforms
Suggested Use Level: 2.0 - 5.0%
Suggested Applications: Cellular Respiration, Collagen Production, Probiotic, Soothing, ATP Synthesis
ACB Yogurt Dermal Respiratory Factor PF
Technical Information
• Lactobacillus bulgaricus cells are stressed with UV radiation
Cells secrete stress response factors (also called heat shock proteins (HSP’s) or heat response elements )
Biofermenation and various filtration techniques are used to then isolate and extract the secretion from live bacteria
• Non-Animal Derived + Non-Dairy
• Derived from bacteria that is used to inoculate milk to create yogurt
ACB Yogurt Dermal Respiratory Factor PF
Lactobacillus bulgaricus
Increases oxygen uptake/cellular respiration
Antioxidant
Enhances ATP Synthesis/cellular energy
Enhances collagen production
Increases fibroblast proliferation
Reduces Redness - Soothing
Ideal for use in baby care, after sun care, sensitive skin, scalp careapplications and to provide potent anti-aging benefits
ACB Yogurt Dermal Respiratory Factor PF
Product Benefits
Oxygen Uptake Assay
Protocol• Increased oxygen uptake indicates
cellular respiration
• Cultured human fibroblasts were used
• According to the results, 5% ACB Yogurt Dermal Respiratory Factor PF can substantially increase oxygen uptake
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106LYCD ACB Yogurt Dermal Respiratory Factor PF
Figure 1: Oxygen Uptake of ACB Yogurt Dermal Respiratory FactorPF compared to LYCD.
Perc
ent(
%) I
ncre
ase
*LYCD or Live Yeast Cell Derivative has traditionally been used to measure oxygen uptake.
ACB Yogurt Dermal Respiratory Factor PF
Figure 2: Increase in collagen production following application of ACB Yogurt DermalRespiratory Factor PF .
Collagen Production Assay
Protocol
• Collagen I is a major component ofthe dermis & provides structure &elasticity to the skin
• Three dose levels were compared to the control – 1%, 2% & 4%
• Results were determined by the ELISA Assay
• According to the results, 4% ACBYogurt Dermal Respiratory Factor PF was most effective at increasing Collagen I synthesis
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Control 1% ACB Yogurt Dermal 2% ACB Yogurt Dermal 4% ACB Yogurt Dermal Respiratory Factor PF Respiratory Factor PF Respiratory Factor PF
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ACB Yogurt Dermal Respiratory Factor PF
ATP Synthesis Assay
Protocol
• An increase in ATP synthesis demonstrates an increase in cellular metbolism
• After 24 hours there was a 42% increase in ATP levels
• ACB Yogurt Dermal RespiratoryFactor PF showed a significant increase in ATP levels compared to the control
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• 2.0% ACB Yogurt Dermal Respiratory Factor PF was tested
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Control ACB Yogurt Dermal Respiratory Factor PF
Figure 3: Increase in ATP Synthesis following application of ACB YogurtDermal Respiratory Factor PF .
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ent(
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ncre
ase
ACB Yogurt Dermal Respiratory Factor PF
ORAC Assay
Protocol
• Trolox is used as the positive control
• Solutions were prepared at two concentrations for a reference
• Fluorescent measurements weretaken every 2 minutes for 2 hours
• ACB Yogurt Dermal Respiratory Factor PF at 2.0% & 4.0%.
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100µM Trolox 125µM Trolox 4% AC Yogurt DRF PF
Figure 4: Results of antioxidant capacity of testmaterials.
2% ACB Yogurt DRFPF
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xida
ntCa
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ty(µ
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ACB Yogurt Dermal Respiratory Factor PF
Anti-Irritation Assay – Average Rating
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05.0% ACB Yogurt DRF PF Placebo
Figure 5: Average anti-irritancy ratings for ACB Yogurt Dermal Respiratory Factor PFcompared to theplacebo.
Impr
ovem
entR
atin
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Protocol
• Subjects: 10 (m/f)
5• Test area: Volar Forearm
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• Concentration of active used: 5.0%
• Frequency of application: TwiceDaily
ACB Yogurt Dermal Respiratory Factor PF
Figure 6: Subject 1 - Before
Anti-Irritation Assay – Before & After Pictures
Subject 1 - After
Figure 7: Subject 2 - Before Subject 2 - After
Pictures were taken right after irritation & 15 minutes after application of 5% ACB Yogurt DRF PF
The images show a significant reduction in redness/irritation after using ACB Yogurt DRF PF
ACB Yogurt Dermal Respiratory Factor PF
Product Code: 20224PF
INCI Name: Lactobacillus Ferment Lysate Filtrate
INCI Status: Conforms
Suggested Use Level: 2.0 - 5.0%
Suggested Applications: Cellular Respiration, Collagen Production, Probiotic, Soothing, ATP Synthesis
Technical Information
ACB Yogurt Dermal Respiratory Factor PF
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ACB Yogurt Dermal Respiratory Factor PF