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Coronary Artery Bypass Grafting (CABG) Ashish Correa, MD Cardiovascular Diseases Fellow Mount Sinai Heart Mount Sinai Morningside/Mount Sinai West Icahn School of Medicine at Mount Sinai New York, NY ACC Young Scholars Show and Tell Webinar

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Page 1: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

Coronary Artery Bypass Grafting (CABG)

Ashish Correa, MDCardiovascular Diseases FellowMount Sinai HeartMount Sinai Morningside/Mount Sinai WestIcahn School of Medicine at Mount SinaiNew York, NY

ACC Young Scholars Show and Tell Webinar

Page 2: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

Our Patient• 63 year old woman.

• Frequent episodes of severe “squeezing” pain in her chest.

• On walking short distances or climbing more than half a flight of stairs.

• Recently getting episodes of pain while sitting down or lying in bed.

• Medical history of … Hypertension (high blood pressure) Hyperlipidemia (elevated levels of cholesterol and

fat in the blood stream) Diabetes mellitus (high blood sugar)

• Never smoked, and eats healthy.

Page 3: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

Medical Work-up• Electrocardiogram (EKG) is unremarkable.

• Blood sugar and cholesterol not very well controlled. Blood pressure is higher than it should be.

• Sent to an imaging specialist.

• Echocardiogram shows that her ejection fraction is low (pump function of the heart is reduced).

• CT (computed tomography) of her heart vessels (coronary arteries) shows extensive blockages.

Page 4: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

Coronary Arteries

Page 5: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

Looking at the Coronary Arteries

Achenbach et al. Heart, 2010

CT Coronary Angiography Invasive Coronary Angiography

Page 6: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School
Page 7: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School
Page 8: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School
Page 9: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School
Page 10: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

What to do next?

Medical management

Percutaneous coronary interventions (with stents)

Bypass surgery

Page 11: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

The Heart Team

HEARTTEAM

Page 12: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

What is Bypass Surgery?• Coronary Artery Bypass Grafting (CABG), Bypass Surgery, “Open Heart” Surgery

• This is a surgical procedure, whereby the surgeon uses segments of blood vessels from other parts of the body (called grafts) to divert blood flow (or bypass) from the aorta to below the blockage.

• The graft can be a vessel arising from the aorta, that normally supplies the chest wall, that gets re-routed to a blocked coronary (internal mammillary artery graft).

• Alternatively, it can be a vein harvested from the leg (vein graft), with one end connected to the aorta and the other end attached below the blockage. University of California - San Francisco, Department of Cardiothoracic Surgery

Page 13: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

Taggart et al. Annals of Cardiothoracic Surgery, 2018.

Continuum Health Partners

Internal Mammary Artery Grafts

Page 14: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

Alexander & Smith. N Engl J Med, 2016.

Saphenous Vein Grafts

Page 15: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

Blitz et al. Annals of Cardiothoracic Surgery, 2013.

Radial ArteryGrafts

Page 16: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

The surgery: extracorporeal bypass, the heart-lung machine and cardioplegia

Thoracickey.com

Premierheartcarett.com

Page 17: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

The surgery: deploying the grafts

Cleveland Clinic Foundation

Page 18: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

Cleveland Clinic FoundationMayo Clinic

Minimally-invasive Robotic-assisted

Off-pump

The surgery: advances

Page 19: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School

Life after surgery

• In the first few days after surgery, our patient felt worse.

• But then she felt better, was discharged from the hospital and in 2 months, she had fully recovered.

• She took her heart medications consistently.

• She inducted herself in cardiac rehabilitation.

• She exercised regularly, dieted and lost weight.

• She no longer had chest pain, and felt that her energy levels had increased.

Page 20: ACC Young Scholars Show and Tell Webinar Coronary Artery .../media/Non-Clinical/Files... · 4/16/2020  · Mount Sinai Heart. Mount Sinai Morningside/Mount Sinai West. Icahn School