Actions of the MALWEST project for malaria

Christos Hadjichristodoulou Professor of Hygiene and Epidemiology Medical Faculty, University of Thessaly

24 – 25 February 2014, Athens, Final Workshop of MALWEST project

Integrated surveillance and control programme for West Nile Virus and malaria in Greece (MIS 365280)

Co-funded by the European Union

MALWEST project

• “Integrated surveillance and control programme for West Nile virus and malaria in Greece”

• National Strategic Reference Framework 2007-2013

• Co-funded by Greece and the EU through the Greek Ministry of Health

• Duration: 01/01/2012 – 31/12/2013 o Extension: 31/12/2014 for two actions (survey on mosquito trap and malaria

surveillance in Regional Unit of Lakonia)

• Aim development of an Integrated Control programme related to WNV(surveillance for human cases, mosquito surveillance, avian surveillance, and equine surveillance) and malaria (surveillance for human cases, mosquito surveillance).

MALWEST Partners • Coordination:

– Department of Hygiene and Epidemiology, Medical Faculty, University of Thessaly

• Collaborating partners:

– Hellenic Center for Disease Control and Prevention

– National School of Public Health

– Laboratory of Microbiology, Medical School, National and Kapodistrian University of Athens

– Arboviruses Reference Laboratory, Aristotle University of Thessaloniki

– Laboratory of Entomology and Agricultural Zoology, Department of Agriculture Crop Production, University of Thessaly

– Pesticides Chemical Control, Benaki Phytopathological Institute

– Faculty of Veterinary Medicine, University of Thessaly

– Laboratory of Microbiology and Infectious Diseases, School of Veterinary Medicine, Aristotle University of Thessaloniki

– Regional Public Health Laboratory of Crete

– Laboratory of Genetics, Evolutionary and Comparative Biology, Department of Biochemistry and Biotechnology, University of Thessaly

– Laboratory for Spatial Analysis, GIS and Thematic Cartography, Department of Planning and Regional Development, School of Engineering, University of Thessaly

– Laboratory of Biochemistry and Applied Biology, Department of Biology, University of Crete

General objectives regarding malaria

• Detection and mapping of plasmodium activity

• Assessment of malaria impact on public health

• Detection of high risk geographical areas

• Prediction of spreading of the disease

• Implementation and assessment of appropriate interventions

Actions of MALWEST programme for malaria according to Work Packages (WP)

WP1: Coordination of the project, dissemination of the results

• Kick-off meeting: 26-27 January 2012

• Stratification of Greece in four risk levels for malaria (0, 1, 2, 3)

• 12 working group meetings (http://www.malwest.gr/el-

gr/%CF%80%CF%81%CE%B1%CE%BA%CF%84%CE%B9%CE%BA%CE%AC%CF%83%CF%85%CE%BD%CE%B1%CE%BD%CF%84%CE%AE%CF%83%CE%B5%CF%89%CE%BD.aspx)

• 4 progress reports per activity per leader (one every 6 months)

• Evaluation reports (interim and final)

• Web portal (www.malwest.gr) – MALWEST project information and progress

– Useful information for healthcare professionals and the public

– Malaria e-learning platform for health professionals

– Web-based GIS

WP1: Dissemination of the results – Web portal

Information regarding MALWEST

project

Information regarding

malaria for healthcare

professionals and the public

Malaria e-learning platform

WP1: Modules of e-learning platform

Lesson title 1st lesson

2nd lesson

Interactive powerpoint

presentation for each lesson

Explanatory video

Self-assessment questionnaire for

each lesson

WP1: E-learning platform

WP1: E-learning platform

WP1: E-learning platform

WP1: E-learning platform – Self assessment

WP1: E-learning platform – Self assessment

WP1: Dissemination of the results - GIS

Mapping of the total number of malaria cases, 2011-2012

Anopheles mosquito detection in areas were surveillance took place

WP1: Dissemination of the results - GIS

WP2: State of the art for malaria surveillance and control

• Systematic review of the current knowledge on malaria with an emphasis on Europe and Greece Malaria manual

• Contents:

– Epidemiology of malaria in Europe and Greece

– Re-emergence of malaria

– Clinical manifestations and diagnosis

– Treatment and prevention

– Surveillance and risk assessment

– Mosquito control

WP2: State of the art for malaria surveillance and control

WP3: Study on presence, seasonal variation and spatial distribution of mosquitoes and design of an

Integrated Mosquito Management plan

• National mosquito surveillance 2012

• Focused mosquito surveillance 2013

• Focused surveillance in Lakonia Regional Unit 2012-2013

• Evaluation of insecticide toxicity and mosquito resistance

• Systematic comparison study on mosquito-trap

WP5: Seroepidemiological study for malaria

• Seroprevalence assessment of malaria antibodies in immigrant and Greek population in Evrotas municipality, Lakonia Regional Unit

• Pilot study – 2012

• 248 asymptomatic Greek citizens

• 721 asymptomatic immigrants

• Levels of seropositivity in immigrants differed between ELISA methods

• Decision about mass drug administration

WP6: Enhanced surveillance for human cases

• Focus investigation for every local case

• Active case detection

• Fever screening

– Regular house visits – Evrotas municipality

• Mass screening (RDT, micro, PCR)

– Evrotas municipality (Lakonia Regional Unit)

– Marathon municipality (East Attica Regional Unit)

– Points of entry

• Plasmodium genotyping

WP7: Targeted intervention activities

• Training seminars for laboratory doctors in risk level areas 2 and 3

• Informative lectures for healthcare professionals in risk level areas 2 and 3

• Awareness seminars for the public (priority to high risk areas)

• Awareness raising information material disseminated in public by the HCDCP

Evrotas municipality

Mass drug administration

Bed net distribution

Indoor residual spraying

Thank you for your attention