acute eriatrics - rcp london
TRANSCRIPT
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ACUTE GERIATRICS
Dr Natalie King FRCP
Clinical lead for Acute Medicine
Surrey and Sussex Healthcare NHS Trust
Head of KSS School of Pas
FPARCP board
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What is acute geriatrics?
Understanding the concept of Frailty
Clinical case
OVERVIEW
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What is Acute Geriatrics?
Provision of care at or before presentation to ED
GP screening and pre-optimisation
Multidisciplinary care
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Why do we need Acute Geriatric care?
Demographic changes
Heterogeneity of older people
Atypical presentation
Complex patients are
-more likely to need admission
-less likely to be discharged from AMU
-have longer LOS
-higher readmission rates
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CGA
Comprehensive Geriatric Assessment (CGA) provides an evidence-based model for the provision of the co-ordinated multi-disciplinary care that these patients need
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How do we target those in need?
• Age versus needs based services
• Front door geriatric MDTs/acute geriatric units
To identify those at risk or in need you need to understand a little about frailty….
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Frailty-distinct clinical entity from normal ageing
Consisting of • Multisystem dysregulation
Leading to • Loss of physiological reserve
Leading to
• A state of increased vulnerability to stressors
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Frailty
• Affects 10% of those over 65yrs
• Rises to 25%-50% of those over 85yrs
Frailty
Disability Long term conditions
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Theories
Phenotype-Fried
• Five predefined physical frailty criteria
• Not frail 0
• Pre-frail 1-2
• Frail 3-5
Accumulation of deficits- Rockwood
• Deficits across various domains (eg cognition, physical functioning, self related health, smoking, history and lab results)
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Recognising frailty in an individual
• Validated assessment tools:
Walking speed
Timed get up and go test
GP assessment
Polypharmacy (>5 medications)
Self reported health <6/10
The Groningen questionnaire (postal)
PRISMA 7 questionnaire
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PRISMA 7
1. Are you more than 85 years? 2. Male? 3. In general do you have any health problems that
require you to limit your activities? 4. Do you need someone to help you on a regular basis? 5. In general do you have any health problems that
require you to stay at home? 6. In case of need can you count on someone close to you? 7. Do you regularly use a stick, walker or wheelchair to get
about?
• Over 3 is considered to identify frailty
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Frailty Index (Rockwood)
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The 5 frailty syndromes
Geriatric Giants
Falls
Immobility
Delirium Incontinence
Iatrogenic (medications)
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Clinical case
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Mrs J
86yrs lives alone
Widowed
2am- goes to bathroom at home
Unable to get off the toilet
Calls lifeline
No formal care
PMH- HTN, Osteoporosis, previous Colles fracture
Drugs
• Adcal D3
• Alendronate weekly
• Bendrofluazide
• Amlodipine
• Aspirin
• Co-codamol 8/500
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Examination
BP 105/70
HR 60 Reg
HS normal
JVP normal
Chest bibasal crackles
Mild ankle oedema
Abdo SNT
Neuro- “moving all 4 limbs”
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Investigations
Na 130
K 4.2
Urea 8.2
Creat 72
ALT 42, ALP 168
CRP 14
WC 9.4
Hb 113
Plt 180
Urine- leuc 1, Nit +
CXR- “Clear”
ECG- SR, nil acute
Trop 28
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What was the working diagnosis?
www.freeimages.co.uk
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What was the working diagnosis?
“Off legs”
UTI
? “Acopia”
Started on trimethoprim
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Geriatrician’s lens
Seen by Medical team on call
PTWR by Geriatrics
So lets review the case again…
www.freeimages.co.uk
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Mrs J
2am- goes to bathroom at home
Unable to get off the toilet
Calls lifeline
No formal care
ED arrival 3.10am
PMH- HTN, Osteoporosis, previous colles fracture
Drugs
• Adcal D3
• Alendronate weekly
• Bendrofluazide
• Amlodipine
• Aspirin
• Cocodamol 8/500
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Examination
BP 105/70
HR 60 Reg
HS normal
JVP normal
Mild ankle swelling
Chest bibasal crackles
Abdo SNT
Neuro- “moving all 4 limbs”- more!
The missing pieces
General inspection
Check for sensory deficits
Check mouth
Skin and joints
Cognitive assessment
Functional assessment
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Na 130
K 4.2
Urea 9.0
Creat 72
ALT 42, ALP 168
CRP 14
WC 9.4
Hb 113
Plt 180
Urine- leuc 1, Nit +
CXR- bibasal atelactasis
ECG- SR poor R wave progression
Trop 28
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Problem list
Decline in physical and functional ability
Hyponatraemia
Signs of cognitive decline on screening
High ALP - ?2nd osteomalacia ? Liver congestion
UTI possible given history of UI
FRAILTY
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Decline in physical and functional ability
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Frailty can lead to decline
Functional decline
“the inability to perform usual activities of daily living due to weakness, reduced muscle strength, and reduced exercise capacity”
Can occur due to deconditioning and acute illness during hospitalization
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“Off legs” in the elderly
Ageing causes:
Reduced muscle strength
Reduced aerobic capacity
Vasomotor instability
Baroreceptor insensitivity
Reduced sensory capacity
Chronic illness and comorbidity can heighten these
Usually as a result of acute illness and reduced functional
reserve
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Functional decline
• 8% of those >65yr need help with >1 ADL rising to 30% men and 50% of women over 85
• Preadmission health and functional status can predict risk of decline
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The effects of bed rest
System Effect
Cardiovascular ↓ Stroke volume, ↓ cardiac output, orthostatic hypotension
Respiratory ↓ Respiratory excursion, ↓ oxygen uptake, ↑ potential for atelectasis
Muscles ↓ Muscle strength, ↓ muscle blood flow
Bone ↑ Bone loss, ↓ bone density
GI Malnutrition, anorexia, constipation
GU Incontinence
Skin Sheering force, potential for skin breakdown
Psychological Social isolation, anxiety, depression, disorientation
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“Acopia”
Pejorative term used to describe inability to perform ADL, no acute medical problems or inappropriate admission
Studies have shown many with “acopia” have complex comorbidities needing specialist input
One study of 93 acopia admissions – Over half presented with a geriatric syndrome
– Only 5 had no acute medical issues
– 22% died
Kee and Rippingale Age and Ageing 2009 38(1):103-105
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Hyponatraemia
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Hyponatraemia in the elderly
The most common electrolyte abnormality in the elderly
• Associated with increased mortality
• Asymptomatic hyponatraemia may contribute to cognitive disorders, posture and gait impairment
• Independent risk factor for falls and osteoporosis
• In up to 50% of presumed SIADH- no cause found
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High ALP ?Osteomalacia
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Osteomalacia
Calcium- low/normal
Phosphate- low/normal
ALP raised PTH raised
Slide 34
Poor bone mineralisation Body aches, muscle weakness and bone fragility Commonest cause in Elderly Vitamin D deficiency Insufficient <50nmol/l Deficient <25nmol/l Established risk factor for falls, Osteoporosis and fractures
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Replacing Vitamin D <25nmol/l
Loading first
First line-1st line: Colecalciferol 20,000 IU capsule: 5 capsules a day for 3 days
2nd line: Colecalciferol 20,000 IU capsule: 3 capsules (60,000 IU) for 8-12 weeks
Then
Maintenance of 800-1000IU/dayOTC high strength vitamin D preparation providing 800-2,000 IU/day + Lifestyle advice
OR
Adcal D3 - 2 daily (containing 400 IU colecalciferol per tablet)
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UTI
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A note on UTI in the elderly
Studies suggest UTI misdiagnosed in 40% of hospitalised elderly *
UTI is however more common and carries 5% 28 day mortality
Urine dip is NOT a diagnostic tool
Prevalence of asymptomatic bacteriuria with age
Asymptomatic bacteriuria should not be treated (NNH 3)
Woodford HJ, George J J Am Geriatr Soc 2009;57:107-14
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So how to apply this to elderly?
A very hard diagnosis
• 1/3 do not have fever
• Bacteriuria doesn’t represent disease
• Leucocytes may be present with or without bacteria
• Complicated UTI implies functional or structural abnormality-male/older female
Full assessment
Presence of symptoms
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Expert consensus
Abx treatment of bacteruria if:
Acute dysuria alone OR
Fever plus at least one of • New or worsening urgency
• Frequency
• Suprapubic pain
• Gross haematuria
• Costovertebral tenderness
• Urinary incontinence
Loeb et al. Infection control and hospital epidemiology 2001;22:120-124
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Elderly and catheters
Dipstick testing has no value *
Only send catheter samples if **
– Fever
– Localising signs
– Systemic features
– Exclusion of other sources first
Change the catheter before antibiotic treatment ( if catheter has been in for >7days)**
* Tambyah PA, Maki DG. Archives of Internal Medicine. 2000;160:673-77 **Tenke et al. Int Journal of Antimicrobial Agents 2008;31S:S68-78
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Cognitive decline
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Progressive decline in memory plus one or more of: aphasia
apraxia
agnosia
disturbed executive function
Abrupt onset
Fluctuant
Hypoactive/hyperactive
Slide 42
Dementia Delirium
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Causes
D Dementia E Electrolyte disorders L Lung, liver, heart, kidney, brain I Infection R Rx Drugs I Injury, Pain, Stress U Unfamiliar environment M Metabolic
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Confusion Assessment Model
Needs 1+2 +3 or 4
1. Acute onset and fluctuating course
2. Inattention
3. Disorganised thinking
4. Altered level of consciousness
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Delirium
• Prevent
Assess for delirium within 24hrs of admission
Avoid ward/bed moves
Correct ward first time
Avoid psychoactive drugs, in fact all drugs!
Orientation (day/night/clocks)
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Back to Mrs J
• Stop BFZ
• Stop co-codamol and objectively measure pain
• PT /OT assessment of functional ability
• Cognitive assessment
• Check Ca/Vit D level
• Stop antibiotics unless febrile/symptoms
• Repeat ECG but if no changes not for repeat troponin
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Hospital stay
Collateral history
Cognition assessment
Nutritional assessment
Full functional assessment
Therapies
Medication review
Discharge planning
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Medications implicated in frailty
Hypnotics
falls
Benzodiazepines
falls
Sulphonylureas
falls
Opiate based analgesics
delirium
Antimuscarinics
Cognitive impairment
NSAIDs
Renal failure
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Before going home
• Reablement package
• Voluntary services
• Communication with GP
• Communication with family/carers
• Communication with patient
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Key recommendations for managing frailty
• Detailed physical, functional, social and physiological
needs assessment (MDT)
• Identify and manage reversible causes
• Refer to geriatric medicine where frailty is associated with significant complexity, diagnostic uncertainty or challenging symptom control
• Review medication using STOPP-START criteria
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Key recommendations for managing frailty
• Use clinical judgement and patient goals when applying disease based evidenced treatments
• Create a personal care plan for each patient which might include ACP/EOLC planning
• Communicate across the healthcare economy
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www.surreyandsussex.nhs.uk/our-services/a-z-of-services/post-graduate-education-centre/kent-surrey-and-sussex-school-of-physician-associates/