Additives for

PERSONAL CARE &

HOME CARE

Working for a sustainable life

introduction of Chemipol

Chemipol is a chemical company established in 1979, manufacturer and supplier of a wide range of biocides,

additives and process chemicals.

We provide innovative technologies, highly effective products and expert support services through specialized technical sales

groups with outstanding expertise in customer point of view.

Head office, production and laboratories: Spain (near Barcelona)

Commercial offices:

Egypt (El Cairo) – Middle East

China (Shanghai) – China

Mexico (Queretaro) – Mexico

Distribution network with distributors in more than

70 countries.

Agrochemicals Emulsions and adhesives

Oil and fuel Detergency

Metalworking Coatings

Paper Cosmetics and Personal Care

Desalinization Treatment of cooling towers

Wastewater treatment Potabilization

Chemipol supplies preservatives, formulation additives and process additives to the following sectors:

introduction of Chemipol

EFECTIVENESS:

Minimal Inhibitori Concentration

preservative testing

CHALLENGE TEST

Inoculum:

UNE 11930 STANDARD (1 Million of microorganism for each sample tested)gram +(S. aureus), gram – (E. coli and P. aeuroginosa), fungi (A.niger) and yeast (C. albicans).

CCT (COSMETIC CHALENGE TEST) (Between 10-20 Million of microorganism on each sample tested)A mixture culture of gram + (S. aureus), gram – (E. coli and P. aeuroginosa), fungi (A.niger) and yeasts (C. albicans).

Incubation:

UNE 11930 STANDARDIndividual incubation and counting.

CCTMixture incubation and counting (more actual)

Count:

UNE 11930 Readings after 7, 14 and 28 days, independent count

CCT Strike after 7 days for each 4 inoculation, pool count

Preservative testing

CHALLENGE TEST

Result assessment CCT

Result assessment based on UNE 11930 criteria of acceptance.

Microbial reduction relative to the accumulated inoculum (log N0 – log Nx).

The antimicrobial efficacy is considered successful when the results show the following criteria:

- Bacteria require a 3 log reduction at the end of 4 cycle of inoculation.

- Mould & Yeast 1 log reduction at the end of 4 cycle of inoculation.

- Accepted deviation of 0,5 log. Possible increasing between cycles caused by the new inoculation

Bacteria

-- Heavy growth (x > 106) No Log red

- Moderate growth (106 > x > 104) < 2,5 Log red

+ Well preserved (UNE&Pharma method)(104 > x > 103) > 2,5 Log red

++ Optimum value (CCT chemipol test) (x < 103) > 3 Log red

Fungi & Yeast

-- Heavy growth (x >105) No Log red

- Moderate growth (>105 > x > 5x104) < 0,5 Log red

+ Well preserved (UNE&Pharma method) (5x104 > x > 1x104) > 0,5 Log red

++ Optimum value (CCT chemipol test) (x < 104) > 1 Log red

Properties of the heterocyclic compounds

Household active ingredients preservation

ACTIVES CMIT/MIT BIT BIT/MIT

CE Number247-500-7

220-239-6220-120-9

220-120-9

220-239-6

CAS Number 55965-84-9 2634-33-552634-33-5

2682-20-4

Efficacy High Low Medium

Activity - Spectra Very wide Pseudomonas Very wide

pH stability 3.0 – 9.0 3.0 – 13.0 3.0 – 10.0

Thermal stability 55 – 60 °C 80 °C 80 °C

Reactions Reducing agents Oxidizing agents Stable

Use General Softeners pH 10 / softeners

Preservation cost x 1 x 8 x 4

Labelling EUH208/H 317 1,5 / 15 ppm 50 / 500 ppm 100 / 1000 ppm

0

10

20

30

40

50

60

70

80

90

100

110

120

130

140

150

160

170

180

190

200

210

220

230

240

250

Pseudomonas aeruginosa Pseudomonas fluorescens Escherichia colI Porteus vulgaris Staphylococcus aureus Bacillus subtilus Aspergillus niger Penicillium funiculosum

c.m

.i (

ppm

)

Organismes

Microbiolgical activity of heterocyclic compounds

CMIT/MIT

MIT/BIT

BIT

active ingredients

Minimal inhibitory concentration ( ppm )

Microorganisms TypeCMIT/MIT

3:1

MIT/BIT

1:1BIT

Pseudomonas aeruginosa gram - 5 20 250

Pseudomonas fluorescens gram - 2 15 100

Escherichia coli gram - 8 10 100

Proteus vulgaris gram - 4 10 100

Staphilococcus aureus gram + 5 30 100

Bacillus subtilus gram + 2 40 20

Aspergillus niger Hongo 5 50 200

Penicillium funiculosum Hongo 1 50 100

Preservative CMIT/MIT MIT/BIT BIT observation

0,1% BIOPOL WJ 15 OK

0,2% BIOPOL XM 100 OK

0,1% BIOPOL VR 20 200 not enough

¿ Why use CMIT/MIT?

SOLUBILITY

His very low log pow guarantee the perfect

homogenization in water based products ,

improving the contact with the microorganism,

minimizing the contact time with the bacteria

and improving the cellular death .

WIDE ACTIVITY SPECTRA

Multidiane ingredient , active against bacteries , moulds, yeast and algae by it´s

method of action that affect the krebs cycle that all of microorganism have some part in

his metabolism functions.

TOXICITY & BIODEGRADABILITY

Sensitizing product at 15 ppm of active

ingredient (2-3 times the m.i.c. worst case).

Free CMR preservative solution.

Environment reduced impact

COMPATIBILITY

Excellent compatibility with detergents and cosmetics raw materials .Possible to use

combined with other actives

CMIT

MIT

CMIT/MIT ® Unique mechanism of action

CMIT/MIT is an active with a unique method of action based in a enzymatic disruption attack that improve inhibition of respiration ,ATP generation and the assimilation growing.

The disruption of the cellular metabolism and the accumulation of damage beyond the capacity of the cell to repair results in cell death , this disruption action combined with electrophilic direct

attack , secondary electrophile generation and an intracellular generation of free radicals stresses the cell´s natural radical defense mechanism .

KREBS CYCLE

*Alpha-

Ketoglutarate

* Pyruvate

* Succinate

Dehydrogenase

NUTRITIONAL

METABOLISM

* Lactate

Dehydrogenase

ATP

GENERATION

* NADH

Dehydrogenase

Advantages of the blends of actives ingredients

Better response to massive contaminations that can happen with reused water.

Effectivity enhancement: they combine short term disinfection with long term preservation.

Improve and complement the activity spectra, capacity for vapour phase protection.

Improve the stability of the heterocyclic compounds, reducing labelling requirements and costs.

Products offered by CHEMIPOL

active ingredients

PRODUCTS

Free formaldehyde actives Formaldehyde releasers / donors

Heterocyclic compounds O-formal N-formal C-methylol

CMIT/MIT BIT MIT/BIT EGHF TMAD BNPD

BIOPOL WJ X

BIOPOL JM X X

BIOPOL MSO X X

BIOPOL IB X X

BIOPOL VR X

BIOPOL XM X

BIOPOL XMT X X

BIOPOL XMB X X

SANIPOL 103 Disinfectant of specific action based on DBNPA

preservation in cosmetics

Preservatives

Organized in two wide range of products and solutions for the protection for leave-on and rinse-off cosmetic

products as innovative and classic formulations.

SENSICARE® C

Low toxicity preservatives, innovative

solutions, based on the innovative

use of existing active substances for

preservation of cosmetic products.

BIOPOL®

Preservatives based on classic active

substances.

Products we supply to the cosmetic industry:

Chemipol supplies preservative agents for leave-on and rinse-off products of Personal Care and cosmetic

formulations. Our portfolio of preservatives covers a wide range of antibacterial active substances for classical and

more innovative formulations for the control of bacterial, molds and yeasts development in cosmetic products.

Chemipol’s classic preservation systems

Product

CATEGORY

Face

cleansingFace care

Shaving

products

Body

cleansingBody care

Sun

protection

Hair

cleansingHair care Hair styling

Decorative

cosmetics

Wet

wipes

BIOPOL C 20 � � � �

BIOPOL C 30 � � � �

BIOPOL MI 10 � � � �

BIOPOL DHN � � � � � � � � � � �

BIOPOL DHI � � � �

BIOPOL DHK � � � � � � � � � � �

BIOPOL DHP � � � � � � � �

BIOPOL PB 6 � � � � � � �

BIOPOL PB 17 � � � � � � �

� especially recommended � recommended � possible

Plant hygiene

Hygiene plant products

Chemipol have under the brand SANIPOL® a family of a full range of products or the plant hygiene including cleansing products for the production facilities and sanitizing solutions for the cleaning of cosmetic facilities. BIOCHECK® is an analysis kit for the microbiological checking of products and raw

materials.

SANIPOL®

Formulations based on different biocidal active

substances, surfactants and dispersing agents.

Benefits

Cleansing

Disinfection

Elimination of solids and fatty residues.

BIOCHEK®

Dip slides for microbiological control, quick and simple. It is

recommended for the verification of the correct state of the

raw materials, end product and facilities.

Benefits

Easy to use

Minimize the necessities of a microbiological laboratory

Control of bacteria and fungi with the same test

innovative preservation systems

SENSICARE® is an innovative range of preservatives for protection of all type of leave-on and rinse-off

products.

The range includes liquid and powder formulations combining the following active substances among

others.

Phenoxyethanol

Benzyl Alcohol

Dehydroacetic Acid

Sorbic Acid / Potassium Sorbate

Benzoic Acid / Sodium Benzoate

Piroctone Olamine

Glyceril Laurate

Ethylhexylglycerin

Gluconolactone

Caprylyl Glycol

innovative preservation systems

SENSICARE® is a new range of preservatives based on active substances with improved eco-

toxicity.

Inspired in the microbial control technology from the food industry, Chemipol started a modern research

program to develop innovative preservatives for the personal care industry.

The objective was to decrease the amount of biocidal actives in contact with the skin while, at the same

time, ensuring optimum protection.

The successful result of this on-going research program is the preservatives range SENSICARE® based

on the concept of self-preservation and hurdle technology for the microbial control.

ORGANIC ACIDS AND ITS SALTS are considered together with

benzyl alcohol as a unique category respect human health because

they are quickly metabolized (24 hours) and excreted of our body

through the common pathways.

The method of action of all organic acids are based in the protonated

acid form that enter in the cell crossing the membrane, only the

protonated can do this process the neutralized form it´s rejected by

the membrane.Inside of the cell the acid will be dissociated and

change the internal pH of microorganism. The bacteria need to pump

outside the protons and need to chapt the most quantity of Na to

neutralize this acid pH , this energy consumer process and the

internal pH cause a stress situation that becomes in the death of the

microorganism.

Bacteria can inactivate this method of action neutralizing inside the

cell the protonated acid with sodium and extract the neutralized form

out of the cell being rejected by the membrane again.

organic acids

Bacteria

Lipid membraneOrganic acid

External aqueous phase

boosting technology

Glyceryl Laurate method of action

For its acceptable toxicity and stability over a wide range of formulations,

phenoxyethanol has become an active present in a large number of preservation

systems.

Glyceril laurate is a mild natural based surfactant derived from glycerin and lauric

acid that boosts the antimicrobial efficacy of phenoxyethanol, acids and benzyl

alcohol by acting on the surface tension of the microorganisms’ cell membrane.

Glyceryl laurate also shows hair conditioning properties and it is a strategic

ingredient for non-grease skincare formulations.

Acts as a co-emulsifier with other surfactants.

Enhances the aesthetics of formulations with excellent rub-out

Creates superior stability in all types of emulsions.

By its mechanism of action, it allows the development of cosmetic formulations

with lower concentration of preservative substances while providing optimal

preservation.

BacteriaLipid membrane

Glyceryl monoester

External aqueous

phase

SENSICARE® C 1000

SENSICARE® C 1000 is a liquid preservative for personal care formulations based on phenoxyethanol and

glyceril laurate.

It combines the well-known preservation properties of the phenoxytanol, with its acceptable toxicity

profile and excellent stability in personal care formulations, with the boosting capacities of the glyceryl

laurate altogether with its properties as co-emulsifier, improves rub-out and enhanced stability.

PRODUCT ppm productContact time (hours)

10 23 35 47 58 71 96 144

SENSICARE C 1000 2000 - - - - - - - �

SENSICARE C 1000 4000 - - - - - - - -

Phenoxyetanol 6000 - - - - - - � �

Phenoxyetanol 8000 - - - - - - - -

SENSICARE C 1090 4000 - - - - - � � �

SENSICARE C 1090 6000 - - - - - - - -

SENSICARE® C 1000 microbiological profile

The balanced formulation of SENSICARE® C 1000 as preservative reduces the surface tension of the microorganism’s cell membrane, disrupts it and inhibits the metabolic function, impairs the enzymatic activity and occurs microbe inactivation.

SENSICARE® C 1000 is effective against gram-positive bacteria, gram-negative bacteria, molds and yeasts. It requires short contact time to control microbial growth and provides strong self-preservation properties. By its action, when used in a heavily contaminated system may occur loss of active ingredients.

0,18%

0,10%0,09%

0,33%

0,21%

0,00%

0,05%

0,10%

0,15%

0,20%

0,25%

0,30%

0,35%

0,40%

0,45%

0,50%

S. Aureus E. Coli P. Aeuroginosa C. Tropic A. Niger

MIC SENSICARE C 1000

SENSICARE® C 1000 usage

Dose of useThe typical use concentration of SENSICARE® C 1000 in rinse-off and leave-on products is from 0,8% to 1,1%. The recommended dosage is below the maximum concentration authorized according to the Cosmetics Directive 76/768/CEE.It is especially active against gram-positive bacteria causing body odor, being recommended to protect deodorant formulations.

StabilitySENSICARE® C 1000 is stable over a wide range of pH (up to pH 12), temperature (up to 80 ºC) and hydrolysis. It is stable protecting inverse emulsions, direct emulsions and water soluble products.

CompatibilitySENSICARE® C 1000 is compatible with the most common raw materials used in personal care formulations, anionic, no ionic and cationic surfactants, salts and pigments. used in water based no surfactant cosmetics (serums or micellar water) it disperses in water giving a milky appearance,

when used in formulations that must be clear it is recommended the use of solubilizers, such as ethoxylathed castor oil, anionic surfactants, polysorbate , emollients in general about 0.2 %.

SolubilitySENSICARE® C 1000 is partially soluble in water, totally soluble in polar solvents (propylene glycol, propanol and acetone), totally soluble in polyalcohols (sorbitol), and is moderately soluble in aliphatic solvents.

SENSICARE® C 1060 usage

Dose of use & applications

The typical use concentration of SENSICARE® C 1060 in rinse-off products and leave-on products is from 0,4 % to

0,8 %. The recommended dosage is below the maximum concentration authorized according to the Cosmetics

Directive 76/768/CEE 1,2%.It is especially active against gram-positive bacteria causing body odor, being recommended to protect deodorant

formulations , include an specific fungicide.

Free Paraben / Booster Technology / Better efficiency against classic Phenoxyethanol

Stability

SENSICARE® C 1060 is stable over a wide range of pH (up to pH 8), temperature (up to 80 ºC) and hydrolysis. It is

stable protecting inverse emulsions, direct emulsions and water soluble products.

Compatibility

SENSICARE® C 1060 is compatible with the most common raw materials used in personal care formulations,

anionic, no ionic and cationic surfactants, salts and pigments. used in water based no surfactant cosmetics (serums or micellar water) it disperses in water giving a milky appearance, when used in formulations that must be

clear it is recommended the use of solubilizers, such as ethoxylathed castor oil, anionic surfactants, polysorbate ,

emollients in general about 0.2 %.

SolubilitySENSICARE® C 1060 is partially soluble in water, totally soluble in polar solvents (propylene glycol, propanol and

acetone), totally soluble in polyalcohols (sorbitol), and is moderately soluble in aliphatic solvents.

SENSICARE® C 1090 usage

Dose of use & applicationsThe typical use concentration of SENSICARE® C 1090 in rinse-off products 1060 in rinse-off products and leave-on products is from 0,9% to 1,1%. The recommended dosage is below the maximum concentration authorized according to the Cosmetics Directive 76/768/CEE.It is especially active against gram-positive bacteria causing body odor, being recommended to protect deodorant formulations.Free Paraben / Booster Technology / Better efficiency against classic Phenoxyethanol

StabilitySENSICARE® C 1090 is stable over a wide range of pH (up to pH 12), temperature (up to 80 ºC) and hydrolysis. It is stable protecting inverse emulsions, direct emulsions and water soluble products.

CompatibilitySENSICARE® C 1090 High concentrations of surfactants can decrease its effectiveness. is compatible with the most common raw materials used in personal care formulations, anionic, no ionic and cationic surfactants, salts and pigments.

SolubilitySENSICARE® C 1090 is soluble in water, totally soluble in polar solvents (propylene glycol, propanol and acetone), totally soluble in polyalcohols (sorbitol), and is moderately soluble in aliphatic solvents.

SENSICARE® C 3300 usage

Dose of use & applicationsThe typical use concentration of SENSICARE® C 3300 in rinse-off and leave-on products is from 0,8% to 1,1%. The recommended dosage is below the maximum concentration authorized according to the Cosmetics Directive 76/768/CEE.It is especially active against gram-positive bacteria causing body odor, being recommended to protect deodorant formulations.Free Paraben / Free Phenoxyethanol / Booster Technology /Better efficiency against classic Benzyl Alcohol / Green cosmetics / Ecolabel compliment

StabilitySENSICARE® C 3300 is stable over a wide range of pH (up to pH 12), temperature (up to 80 ºC) and hydrolysis. It is stable protecting inverse emulsions, direct emulsions and water soluble products.

CompatibilitySENSICARE® C 3300 is compatible with the most common raw materials used in personal care formulations, anionic, no ionic and cationic surfactants, salts and pigments. used in water based no surfactant cosmetics (serums or micelar water) it disperses in water giving a milky appearance,

when used in formulations that must be clear it is recommended the use of solubilisers, such as ethoxylathed castor oil, anionic surfactants, polysorbate , emollients in general about 0.2 %.

SolubilitySENSICARE® C 3300 is partially soluble in water, totally soluble in polar solvents (propylene glycol, propanol and acetone), totally soluble in polyalcohols (sorbitol), and is moderately soluble in aliphatic solvents.

SENSICARE® M 4200 usage

Dose of use & applications

The typical use concentration of SENSICARE® M 4200 in rinse-off products and in leave-on products is from 1% to

2%. The recommended dosage is below the maximum concentration authorized according to the Cosmetics

Directive 76/768/CEE.It is especially active against gram-positive bacteria causing body odor, being recommended to protect deodorant

formulations.

Free Paraben / Free Phenoxyethanol / Booster Technology / Better efficiency against classic Sodium Benzoate /

Preservative for all different types of face products / Ecocert Preservative

Stability

SENSICARE® M 4200 is stable over a wide range of pH (up to pH 7) but the safety area it´s near 5,5, resistant to temperature (up to 80 ºC). It is stable protecting inverse emulsions, direct emulsions and water soluble products.

Compatibility

SENSICARE® M 4200 is compatible with the most common raw materials used in personal care formulations, anionic, no ionic and cationic surfactants, salts and pigments.

Don´t blend with ascorbic acid , pH stability need to be checked if the pH drop buffer the system ,the buffer can be

sodium lactate/lactic acid , sodium citrate / citric acid ( proportion 1 m4200/ 2 buffer)

Solubility

SENSICARE® M 4200 is soluble in water, totally soluble in polar solvents (propylene glycol, propanol and acetone),

totally soluble in polyalcohols (sorbitol), and aliphatic solvents.

risk evaluation

Spoilage risks0% of probability of spoilage

1. Water Adequate growing medium

2. Ingredients Nutritive elements (organic matter and microelements)

3. Conditions pH, T, growing conditions, oxygen content

4. Lack of hygiene Storage, Production, Filling, Usage

5. Lack of protection Under dosage or inadequate preservative

100% of probability of spoilage

It is vital important for the right prevention policy the identification, elimination and control of

al the possible contamination focuses in the production site and chain of use.

barrier technology

pH buffers

SENSICARE M 4200

• Gluconolactone M4200

• Lactic acid

• Citric acid

Available water chapters

• Glycols

• Glycerin

• Polyalcohol

Quelating Agents

• EDTA

• Glutamic derivate

Antioxidants

SENSICARE FP

• Hydroxyacetophenone

• Tocopherol

• BHT

Membrane-actives

• Glyceryl Laurate

• EthylHexylGlycerin

• Caprylyl Glycol

Preservative

SENSICARE C

• Phenoxyethanol

• Benzyl alcohol

• Organic acids & salts

• Piroctone Olamine

Water Activity Types of proliferable Microorganisms

0.96 to 0.99 Gram-positive and Gram-negative bacteria

(e.g. Ps. species), mold and yeasts

0.90 to 0.95 Several Gram-negative and most Gram-

positive bacteria (e.g. Enterobacter aerogenes,

Escherichia coli, Bacillus species), mold and

yeasts

0.80 to 0.89Gram-positive bacteria (e.g. S. aureus), mold

and yeasts

0.70 to 0.79 Halophilic bacteria, mold and yeasts

0.65 to 0.69 Osmotolerant yeasts

Below 0.6 None

Foundation 0.68

Hand Cream 0.96

Loose Body Powder 0.76

Lipstick 0.68

Mascara 0.96

Powdered Eyeshadow 0.76

Shampoo 0.99

Shampoo Conditioner 0.97

Toothpaste 0.86

Wet/Dry Eyeshadow 0.57

TYPE OF COSMETIC Common Aw

Water Activity Level Antimicrobial Spectrum of a Preservative for Inclusion

Below 0.6 Inclusion of a preservative system may not be necessary.

0.70 – 0.79 Preservative system needs to be active against yeast and mold.

0.80 - 0.89 Preservative system needs to be active against Gram-positive bacteria, yeast and

mold.

0.90 – 0.99Preservative system needs to have a broad spectrum of antimicrobial activity (e.g.

Gram-negative and Gram-positive bacteria, yeast and mold)

AW AVAILABLE WATER

Self protecting formulations / Low sensitization preservative system

0,5 - 2%

• PRESERVATIVE (PHENOXYETHANOL , BENZYL ALCOHOL , ORGANIC ACIDS/SALTS, PIROCTONE OLAMINA)

• BOOSTER (Glyceryl Laurate , Ethylhexylglycerine , Gluconolactone , Caprilyl glycol)

2 - 5%

• Aw CHAPTERS Glycols , Glycerin , Alcohols , Polialcohols

0,1 - 0,2%

• CHELATINGS L-glutamic acid N,N-diacetic acid, EDTA , Policarboxylates

• ANTIOXIDANTS Hidroxyacetophenone , BHT , THBQ , Tocopherol

Benefits of SENSICARE® innovative preservation systems

Product

CATEGORY

Face

cleansing

Face

care

Shaving

products

Body

cleansingBody care

Sun

protection

Hair

cleansingHair care Hair styling

Decorative

cosmetics

Wet

wipes

SENSICARE C 1000 � � � � � � � � � � �

SENSICARE C 1040 � � � � � � � � � � �

SENSICARE C 1045 � � � � � � � � � � �

SENSICARE C 1055 � � � � � � � � � � �

SENSICARE C 1060 � � � � � � � � � � �

SENSICARE C 2010 � � � � � � � � � �

SENSICARE C 3000 � � � � � � � � � � �

SENSICARE C 3300 � � � � � � � � � � �

SENSICARE M 4200 � � � � � � � � � �

� highly recommended � recommended � possible

SENSICARE® preservative free

AOX / QUELATING AGENTS

BIOFLAVONOIDS / POLYPHENOLS

GLYCOLS / GLYCERYN

GLYCERYL ESTERS / ACIDS

• STABILITY TESTED ON PERSONAL

CARE FORMULATIONS

• MICELLAR WATER

HANDCREAM

• BODY CREAM

• PROTEIN SERUM

• HAIR CONDITIONER

• SHAMPOO

• TESTED ANTIMICROBIAL EFFICACY ON

• WATER BASE

• OW EMULSION

• WO EMULSION

• SERUM

• ANIONIC SURFACTANTS

• CATIONIC SURFACTANTS

• BETTER PERFORMANCE

• BETTER COMPATIBILITY

• WIDE PH RANGE

• HIGH TEMPERATURE RESISTANCE

• LESS ODOUR

• LESS COLOUR

• NO SIDE EFFECTS

• NO SENSITIZATION

preservative free testing

SENSICARE® FP preservative free preservation solutions for personal care have been tested on several

frame formulations in order to verify the following parameters.

Compatibility: There is no affectation in the appearance and properties of the personal care product.

Stability: There is no affectation of the SENSICARE® preservation solution at dose level in the personal

care product.

Efficacy: The personal care product is rightly protected

frame formulations

Aqua/Water

Butyrospermum Parkii Butter / Butyrospermum Parkii (Shea) Butter

Caprylic / Capric Triglyceride

Prunus Amygdalus Dulcis Oil / Prunus Amygdalus Dulcis (Sweet Almond) Oil

Glycerin

Cetyl Alcohol

Cetearyl Alcohol

Glyceryl Stearate

Aloe Barbadensis Leaf Juice

Olus Oil/Vegetable Oil

Potassium Palmitoyl Hydrolyzed Wheat Protein

Argania Spinosa Kernel Oil

Citrus Aurantium Dulcis Peel Oil/Citrus Aurantium Dulcis (Orange) Peel Oil

Hydrolyzed Caesalpinia Spinosa Gum / Caesalpinia Spinosa Gum

Glycine Soja Oil / Glycine Soja (Soybean) Oil

Tocopherol

Xanthan Gum

Sodium Phytate

Beta Sitosterol

Squalene

Alcohol

Limonene

Linalool

CitralCitronellol

Aqua/Water,

Rosa Damascena Flower Water,

Citrus Aurantium Dulcis Fruit Water / Citrus Aurantium Dulcis

(Orange) Fruit Water

Poloxamer 184

Glycerin

Coco-Glucoside

Propylene Glycol

Calendula Officinalis Flower Extract

Calcium Gluconate

CitronellolCitral

Micellar water (MW) Natural face cream (NFC)

frame formulations

Aqua/Water

Glycerin

Paraffinum Liquidum / Mineral Oil

Persea Gratissima Oil / Persea Gratissima (Avocado) Oil

Octyldodecanol

Prunus Amygdalus Dulcis Oil / Prunus Amygdalus Dulcis (Sweet Almond) Oil

Caprylic/Capric Triglyceride

Simmondsia Chinensis Oil / Simmond sia Chinensis (Jojoba) Seed Oil

Butyrospermum Parkii Butter / Butyrospermum Parkii Butter (Shea) Butter

Dimethicone

Lecithin

Bisabolol

Sodium Hyaluronate

Hydrolyzed Collagen

Tocopheryl Acetate

Allantoin

Acrylates / C10 – 30 Alkyl Acrylate Crosspolymer

Panthenol

Retinyl Palmitate

Hydroxypropyl Cyclodextrin

Ascorbyl Palmitate

Palmitoyl Tripeptide – 38

Xanthan Gum

Parfum / Fragrance

BHT

Disodium EDTA

Sodium Hydroxide

Linalool

Butylphenyl Methylpropional

HydroxycitronellalLimonene

Anti-aging serum (AAS)

frame formulations

Aqua/Water

Butyrospermum Parkii Butter / Butyrospermum Parkii Butter (Shea) Butter

Cyclopentasiloxane

Isohexadecane

Prunus Amygdalus Dulcis Oil / Prunus Amygdalus Dulcis (Sweet Almond) Oil

Steareth – 2

Cetearyl Isononanoate

Simmondsia Chinensis Seed Oil / Simmondsia Chinensis (jojoba) Seed Oil

Steareth – 21

Glycerin

Zea Mays Oil / Zea Mays (Corn) Oil

Parfum/Fragrance

Lecithin

Tocopheryl Acetate

Allantoin

Rosa Moschata Seed Oil

Centella Asiatica Extract

Helianthus Annuus Seed Oil / Helianthus Annuus (Sunflower) Seed Oil

Sodium Hyaluronate,

Rosmarinus Officinalis Leaf Extract / Rosmarinus Officinalis (Rosemary) Leaf

Extract

Dimethicone

Dimethicone / Vinyl Dimethicone Crosspolymer

Alcohol

Acrylates / C10 – 30 Alkyl Acrylate Crosspolymer

Cetyl Alcohol

Xanthan Gum

BHT

Disodium EDTA,

Sodium Hydroxide

Potassium Phosphate

Hexyl Cinnamal

Linalool

Limonene

Hydroxyisohexyl 3 – Cyclohexene Carboxaldehyde

Alpha – Isomethyl Ionone

Benzyl Salicylate

Coumarin

Moisturizing facial cream (MFC)

frame formulations

Aqua / Water

Isohexadecane

Isopropyl Palmitate

Prunus Amygdalus Dulcis Oil / Prunus Amygdalus Dulcis (Sweet Almond) Oil

Glycerin

Rosa Moschata Seed Oil

Caprylic / Capric Triglyceride

Cyclopentasiloxane

PEG – 30 Dipolyhydroxystearate

Magnesium Sulfate

Zea Mays Oil / Zea Mays (Corn) Oil

Hyaluronic Acid

Tocopheryl Acetate

Retinyl Palmitate

Centella Asiatica Extract

Parfum / Fragrance

Hydrogenated Castor Oil

Helianthus Annuus Seed Oil / Helianthus Annuus (flower) Seed Oil

Rosmarinus Officinalis Leaf Extract / Rosmarinus Officinalis (Rosemary) Leaf

Extract

BHT

Hexyl Cinnamal

Limonene

Linalool

Alpha – Isomethyl Ionone

Butylphenyl Methylpropional

Hydroxyisohexyl 3 – Cyclohexene Carboxaldehyde

Citronellol

Hydroxycitronellal

Citral

External oleo phase moisturizing cream (EOPMC)

frame formulations

Aqua / Water

Sodium Laureth Sulfate

Cocamidopropyl Betaine

PEG – 7

Glyceryl Cocoate

Parfum / Fragrance

Decyl Glucoside

Glycerin

Aloe Barbadensis Leaf Juice

Styrene / Acrylates Copolymer

Glycol Distearate

PEG / PPG – 18 / 18 Dimethicone

PEG – 4 Rapeseedamide

Hydroxypropyl Guar Hydroxypropyltrimonium Chloride

Cocamide MEA

Laureth – 10

Avena Sativa Kernel Extract / Avena Sativa (Oat) Kernel Extract

Panax Ginseng Root Extract

Sodium Chloride

Tetrasodium EDTA

Sodium Hydroxide

Citric Acid

Linalool

Bath gel (BG)

Aqua/Water

Coco-Caprylate / Caprate

Isostearyl Isostearate

Polyglyceryl – 3 Polyricinoleate

Caprylic / Capric Triglyceride

Oryza Sativa Bran Oil / Oryza Sativa (Rice) Oil

Glycerin

Aloe Barbadensis Leaf Juice

Prunus Armeniaca Kernel Oil / Prunus Armeniaca (Apricot) Kernel Oil

Sodium Chloride

Hydrogenated Apricot Kernel Oil

Parfum / Fragrance

Hyaluronic Acid

Glycine Soja Oil / Glycine Soja (Soybean) Oil

Tocopherol

Beta – Sitosterol

Squalene

Tocopherol

Linalool

Natural moisturizing cream (NMC)

tests results

The different frame formulations have been treated with different dosages of the SENSICARE range for preservative free preservation

solution.

Five synthetic frame formulations with 1.5 and 2.0 %

SENSICARE® FP 1

Two natural frame formulations with 1.0 and 1.5 %

SENSICARE ® NAT

The test has been carried out according to

Test for efficacy of antimicrobial preservation (European Pharmacopeia 8th edition)

The results have been given according to the Criteria A and B defined by the method.

MW NFC AAS MFC EOMPC BG NMC

NAT 1.0 % No Tested A No Tested No Tested No Tested No Tested A

1.5 % No Tested A No Tested No Tested No Tested No Tested A

FP 1 1.5 % A No Tested B B B A No Tested

2.0 % No Tested No Tested A A A No Tested No Tested

SENSICARE® FP 1

INCI

Hydroxyacetophenone – antioxidant, anti-irritant*, emulsion stabilizer, antimicrobial

Glyceryl Laurate – emollient, emulsifier

Propylene glycol – humectant, skin conditioning

DOSE

1 – 2%

pH

2 – 10

TARGETED FOR

Baby care, facial care, eye contour, oral care, wet wipes, make up, clear cosmetics

* COX-Z assay, enzyme activity

SENSICARE® FP 1

Dose of use & applicationsThe typical use concentration of SENSICARE® FP 1 in rinse-off products and in leave-on products is from 1% to 2%. The recommended

dosage is according to the Cosmetics Directive 76/768/CEE.

Free Paraben / Free Phenoxyethanol / Free benzyl alcohol

Booster Technology for free preservative formulations

Multifunctional activity due to its components potentiating the anti-oxidizing, skin conditioning and wetting characteristics of the personal

care products

StabilitySENSICARE® FP 1 is stable over a wide range of pH (up to pH 10), temperature (up to 80 ºC) and hydrolysis. It is stable protecting

inverse emulsions, direct emulsions and water soluble products. Recommended storage temperature up to 20ºC

CompatibilitySENSICARE® FP 1 is compatible with the most common raw materials used in personal care formulations, anionic, no ionic and cationic

surfactants, salts and pigments.

SENSICARE® FP 1 used in water based no surfactant cosmetics (serums or micellar water) it disperses in water giving a milky

appearance, when used in formulations that must be clear it is recommended the use of solubilizers, such as ethoxylathed castor oil,

anionic surfactants, polysorbate , emollients in general about 0.2 %.

SolubilitySENSICARE® FP 1 is soluble in water, totally soluble in polar solvents (propylene glycol, propanol and acetone), totally soluble in

polyalcohols (sorbitol), and aliphatic solvents.

SENSICARE® NAT

INCI

Citrus paradisi (grapefruit) Fruit Extract

Citrus paradisi (grapefruit) Seed Extract

Citrus aurantium extract

Citrus sinensis extract

Citrus reticulate (Tangerine) Peel extract

Vegetal glycerine – humectant, moisturizer

Ascorbic acid – antioxidant

Lactic acid – acid

Citric acid – acid

DOSE

1.0 – 2.0 %

pH

2 – 10

TARGETED FOR

Baby care, facial care, wet wipes, make up, green cosmetics, Cosmos, Ecocert, Natrue

humectant, skin conditioning, parfum, antioxidant

SENSICARE® NAT

Dose of use & applicationsThe typical use concentration of SENSICARE® NAT in rinse-off products and in leave-on products is from 1% to 1,5%. The

recommended dosage is according to the Cosmetics Directive 76/768/CEE.

Natural origin preservation for free preservative formulations

Multifunctional activity due to its components potentiating the skin and hair conditioning, anti-oxidizing and wetting characteristics of the

personal care products and a fresh orange fragance.

Free Paraben / Free Phenoxyethanol / Booster Technology / Better efficiency against classic Sodium Benzoate / Preservative for all

different types of green Ecocert / cosmos / Natrue cosmetic

StabilitySENSICARE® NAT is stable over a wide range of pH (up to 10), temperature (up to 80 ºC) and hydrolysis. It is stable protecting inverse

emulsions, direct emulsions and water soluble products.

CompatibilitySENSICARE® NAT is compatible with the most common raw materials used in personal care formulations, anionic, no ionic and cationic

surfactants, salts and pigments. Incidence in the colour need to be check cause acid pH obtain light yellow coloration and higher pH

increase make it intense

SolubilitySENSICARE® NAT is soluble in water, totally soluble in polar solvents (propylene glycol, propanol and acetone), totally soluble in

polyalcohols (sorbitol).

SENSICARE® NAT

MIC and MBCMinimum Inhibitory Concentration (MIC) is understood as the lowest concentration of the preservative solution that inhibits the growth of a determined microorganism.

Minimum Bactericidal Concentration (MBC) is understood as the lowest concentration of the preservation solution that kills 99.9 % of a determined bacteria.

The assays performed on SENSICARE® NAT have shown that the its effectiveness in terms of MIC and MBC is nearly the same, showing

therefore an antibacterial activity at dose level.

MechanismThe complex formulation of SENSICARE® NAT facilitate a multiple path for the interaction of the different active ingredients present in the

system with the microorganisms which will lead to them to a failure and death.

This multiple mechanism of activity increases the antibacterial properties.

MultifunctionalityThe different components of SENSICARE® NAT are not strictly antibacterial agents, and provide to the formulation where used other

properties.

The natural origin of these components of SENSICARE® NAT is responsible for these properties such as antioxidant, humectant,

conditioning etc.

SENSICARE® NAT

Natural extracts

The use of natural sources provides a rich blend of active ingredients that provide a great variety of chemistry.

Many of the components of these extracts have antibacterial properties.

The multiplicity of active ingredients with antibacterial activity ensures a broader activity spectra.

Moreover, other properties are associated to them providing further benefits to their used in personal care formulations.

Phenolic compounds are within these components present in different forms of the family of flavonoids (catechins, epicatechin,

procyanidin, etc.).

Other elements of much interest are ascorbic acid, tocopherols, citric acid, limonoids, sterols, etc.

Flavonoids

Flavonoids are a family of hydroxylated phenolic compounds naturally found in plants and fruits.

They are found in our daily diet.

They provide many benefits to our health.

They have antibacterial properties.

SENSICARE® BIOPOL ® Rinse off Selection guide

RINSE OFF

• 0,2% BIOPOL C 30 (CMIT/MIT+ BENZYL ALCOHOL)

• 0,1% BIOPOL IBC (CMIT/MIT + BRONOPOL)

• 0,1% BIOPOL C 20 (CMIT/MIT)

IF CMIT/MIT IT´S ACCEPTED

• 0,6-0,8% BIOPOL DHN (DMDMHYDANTOINE)

• 0,4-0,8% BIOPOL DHK (DMDMHYDANTOINE + POTASSIUM SORBATE)

• 0,8-1,5% SENSICARE C 2010 (SODIUM BENZOATE / POTASIUM SORBATE)

• 1-2% SENSICARE M 4200 (SODIUM BENZOATE + GLUCONOLACTONE )

IF CMIT/MIT ARE BANNED

BUT IT´S ACCEPTED FORMALDEHYDE RELEASERS &

SODIUM BENZOATE /POTASSIUM SORBATE

IF CMIT/MIT , MIT , FR ,

ARE BANNED BUT IT´S ACCEPTED

PHENOXYETHANOL

• 0,8 - 1 % SENSICARE C 1000 (PHENOXYETHANOL + GLICERYL LAURATE)

• 0,4-0,8 % SENSICARE C 1060 (PHENOXYETHANOL + GLICERYL LAURATE + PIROCTONE OLAMINE)

• 0,9-1,1 % SENSICARE C 1090 (PHENOXYETHANOL + ETHYLHEXYLGLYCERINE)

• 0,6 - 0,8 % BIOPOL PB 6 (METHYL + ETHYL + PROPYL PARABEN + PHENOXYETHANOL )IF PARABENS ARE ACCEPTED

• 0,8 - 1 % SENSICARE C 1000 (PHENOXYETHANOL + GLICERYL LAURATE)

• 0,5 - 0,6 % SENSICARE C 1060 (PHENOXYETHANOL + PIROCTONE OLAMINE+ GLICERYL LAURATE)

• 0,9 - 1 % SENSICARE C 1090 (PHENOXYETHANOL + ETHYLHEXYLGLICERINE)

IF IT´S ACCEPTED PHENOXYETHANOL

IF IT´S ACCEPTED BENZYLALCOHOL SODIUM

BENZOATE /POTASSIUM SORBATE

& ECOLABEL / ECOCERT/COSMOS

• 0,8 - 1 % SENSICARE C 3300 (BENZYLALCOHOL + GLICERYL LAURATE)

• 0,8 - 1 % SENSICARE C 3000 (BENZYLALCOHOL + DEHIDROACETIC ACID)

• 0,8 - 1,5 % SENSICARE M 4200 (SODIUM BENZOATE + GLUCONOLACTONE)

SENSICARE® BIOPOL ® LEAVE ON Selection Guide

IF IT´S NOT ACCEPTED PHENOXYETHANOL

BENZYLALCOHOL SB/PS

• 1 - 2 % SENSICARE FP 1

• 1 - 2% SENSICARE NAT

MercadosACRIPOL T

ACRIPOL T is a complete range of thickeners for detergents.

This product range are developed based in acrylic polymers and copolymers. Performance of this

kind of thickeners is to modify the viscosity of the treated products stabilizing emulsions or

generating a gel consistence in transparent products.

Easy handling and direct use without neutralization are the characteristics of this thickeners range.

PRODUCT APPLICATION POLIMER IONICITY % ACTIVE PRESENTATION pH APPLICATION VISCOSITY TRANSPARECY RECOMENDATION

T 111 DETERGENCY ACRILIC CATIONIC 56 OIL

EMULSION

2 - 5 20.000 NO Softener

Acid detergents

T 112 DETERGENCY ACRILAMIDE ANIONIC 56 WATER

EMULSION

2 - 5 20.000 YES Acid detergents

T 132 DETERGENCY COPOLIMER ANIONIC 50 WATER

EMULSION

6 - 14 20.000 YES Degreasers

Alcaline detergents

MercadosACRIPOL T

ACRIPOL T is a complete range of thickeners for cosmetics and personal care.

This product range are developed based in acrylic polymers and copolymers. Performance of this

kind of thickeners is to modify the viscosity of the treated products stabilizing emulsions or

generating a gel consistence in transparent products. Easy handling and in some cases direct use

without neutralization are the characteristics of this thickeners range.

PRODUCT APPLICATION POLIMER IONICITY % ACTIVE PRESENTATION pH APPLICATION VISCOSITY TRANSPARECY RECOMENDATION

T 210 COSMETIC COPOLIMER ANIONIC 50 WATER

DISPERSION

2 - 11 1% / 20.000 NO Skin care emulsions

T 220 COSMETIC POLIACRILAMIDE ANIONIC 57 WATER

DISPERSION

2 - 11 2% / 32.000 NO Skin care emulsions

T 230 COSMETIC POLYQUAT CATIONIC 53 WATER

DISPERSION

2 - 11 2% / 45.000 NO Hair conditioners

T 250 COSMETIC COPOLIMER ANIONIC 30 WATER

EMULSION

2 - 9 1% / 7.000 YES Surfactant base

T 260 COSMETIC COPOLIMER ANIONIC 20 WATER

EMULSION

2 - 10 10% / 100,000 YES Gels , extracts

T 280 COSMETIC CARBOMER ANIONIC 100 SOLID

GRANULAR

3 - 12 0,2% / 30.000 YES General Applications

ACRIPOL OP

ACRIPOL OP is a range of opacifiers for detergents , cosmetics and personal care. This line of

products are based in a styrene/acrylate dispersion in water.

Easy handling and use is the characteristic of this opacifiers. It is recommended a pre-dilution in

water at 10-20%.

ACRIPOL OP 313 is a water based styrene / acrylate copolymer developed to be used in

cosmetics and detergents with hydroalcoholic blends. It is stabilized in acidic pH

INCI Styrene / acrylates copolymer

Defoamers are products designed to avoid the problems caused by the presence of undesirable foams in the

production sequence, filling actions and application action. Even though are products to preserve the foam

formation and also to eliminate formed foams.

• Industrial grade

• DENSIPOL SI / DENSIPOL RMB / DENSIPOL SI 30

• Food & Cosmetic grade

• DENSIPOL SI 99 / SENSICARE A 1000

SILICONES

• OE/OP Copolymers OE/OP and ethoxylathed fatty

alcohols

• DENSIPOL DF 152 / DENSIPOL DF 800

• Remain transparency and high performance in high

temperature Automatic/CIP cleanings

OE/OP

COPOLYMER

DENSIPOL

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Chemipol S.A.Joan Monpeó 149 · 08224 Terrassa (Barcelona) · Spain

Tel.: +34 937 831 044 · Fax: +34 937 837 580

www.chemipol.com