advances in nucleic acid therapeutics · synthetic organic chemistry and the development of...

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Drug Discovery

Advances in Nucleic Acid Therapeutics

Edited by Sudhir Agrawal and Michael J. Gait

Advance Book Information March 2019

All information is subject to change without notice

Advances in Nucleic Acid TherapeuticsSudhir Agrawal Idera Pharmaceuticals, USA Michael J Gait MRC Laboratory of Molecular Biology (LMB), UK

SynopsisThe sequencing of the human genome and subsequent elucidation of the molecular pathways that are important in the pathology of disease have provided unprecedented opportunities for the development of new therapeutics. Nucleic acid-based drugs have emerged in recent years to yield extremely promising candidates for drug therapy to a wide range of diseases. Advances in Nucleic Acid Therapeutics is a comprehensive review of the latest advances in the field, covering the background of the development of nucleic acids for therapeutic purposes to the array of drug development approaches currently being pursued. Bringing contributions together from leaders at the forefront of progress, this book depicts the many approaches currently being pursued in both academia and industry.

Brief Contents

Series: Drug Discovery

ISSN: 2041-3203

Publisher: Royal Society of Chemistry

ISBN: 9781788012096

Price: £199.00 | $275.00

Publishing date: 19/02/2019

Target Audience: Professional and scholarly

Format: Hardback

Size: 234 x 156mm

Pages: 600

BIC: PNN, PSAK1, PSB

History and development of nucleotide analogs in nucleic acids drugs

Mechanisms of action of antisense oligonucleotides

The medicinal chemistry of RNase H activating antisense oligonucleotides

Antisense technology: liver targeting and beyond for drug discovery

Targeting point mutations with antisense oligonucleotides

Splicing modulation

Targeting toxic repeats

Research and development of oligonucleotides targeting microRNAs

Oligonucleotide targeting of long non-coding RNAs

Conjugate-mediated systemic delivery of RNAi-based therapeutics: enhancing PK/PD relationships of medicinal oligonucleotides

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Food Chemistry, Function and Analysis

Foo

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Anthocyanins from Natural SourcesExploiting Targeted Delivery for Improved Health

Edited by Marianne Su-Ling Brooks and Giovana B. Celli



Anthocyanins from Natural SourcesExploiting Targeted Delivery for Improved Health

Marianne Su-Ling Brooks Dalhousie University, Canada Giovana B Celli Dalhousie University, Canada

SynopsisInterest in anthocyanins has increased in the past few years, due to their potential health-promoting properties as dietary antioxidants, as well as their use as natural dyes. This book discusses ways of targeting the delivery of these compounds, through manipulation of exploitation mechanisms. It addresses all aspects from anthocyanin extraction, health benefits, and metabolism to specialized controlled release applications. This title serves as a reference to those specialising in pharmaceutical science, food engineering, food science or human health and nutrition.

Brief Contents

Series: Food Chemistry, Function and Analysis

ISSN: 2398-0656


ISBN: 9781788012157

Price: £179.00 | $250.00



Format: Hardback

Size: 234 x 156mm

Pages: 400

BIC: MBNH3, PSB, TDCT

Chemistry and Extraction of Anthocyanins: Natural Sources of Anthocyanins

Chemistry of Anthocyanins

Extraction of Anthocyanins from Natural Sources - Methods and

Commercial Considerations

Extraction of Anthocyanins from Food Processing Wastes -

Potential and Issues

Health Benefits and Metabolism: Health Benefits

Pharmacokinetics

The Stability and Absorption of Anthocyanins in the Mouth

Role of the Stomach in Anthocyanin Absorption

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Smart Materials Series

Layered Materials for Energy Storage and ConversionEdited by Dongsheng Geng, Yuan Cheng and Gang Zhang



Layered Materials for Energy Storage and ConversionDongsheng Geng University of Science and Technology Beijing, China Yuan Cheng Institute of High Performance Computing, A*STAR, Singapore Gang Zhang High Performance Computing, A*STAR, Singapore

SynopsisThe considerable interest in graphene and 2D materials is sparking intense research on layered materials due to their unexpected physical, electronic, chemical, and optical properties. After a brief introduction to layered materials, the chapters of this book gather various fascinating topics including electrocatalysis for fuel cells, lithium-ion and sodium-ion batteries, photovoltaic devices, thermoelectric devices, supercapacitors and water splitting. With contributions from key researchers, this book will be of interest to students, researchers and engineers worldwide who want a basic overview of the latest progress and future directions.

Brief Contents

Series: Smart Materials Series

ISSN: 2046-0066


ISBN: 9781788014267

Price: £159.00 | $220.00


Target Audience: College/higher education

Format: Hardback

Size: 234 x 156mm

Pages: 300

BIC: TBN, TGM, THRH

MOFs-derived Materials for Extremely Efficient Electrocatalysis

Two-dimensional layered materials for high-performance

lithium-ion batteries

Intercalation based layered materials for rechargeable sodium-ion batteries

Ionic liquid electrolytes for graphene–based supercapacitor with an

ultrahigh energy density

Properties and applications of layered thermoelectric materials

Graphene-Carbon Nanotube Hybrid Films for High-Performance

Photovoltaic Devices

Metal -organic frameworks (MOFs) as potential hybrid ferroelectric materials

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Specialist Periodical Reports

Organometallic ChemistryVolume 42

Edited by Nathan J. Patmore and Paul I. P. Elliott



Organometallic ChemistryVolume 42

Nathan J Patmore University of Huddersfield, UK Paul I P Elliott University of Huddersfield, UK

SynopsisWith the increase in volume, velocity and variety of information, researchers can find it difficult to keep up to date with the literature in their field. This interdisciplinary field has the potential to provide answers to problems and challenges faced in catalysis, synthetic organic chemistry and the development of therapeutic agents and new materials. Providing an invaluable volume, this volume contains analysed, evaluated and distilled information on the latest in organometallic chemistry research.

Brief Contents

Series: Specialist Periodical Reports

ISSN: 0301-0074


ISBN: 9781788010054

Price: £314.95 | $441.00



Format: Hardback

Size: 234 x 156mm

Pages: 189

BIC: PNND

Recent Developments in Molecular Precursors for Atomic Layer Deposition

Metal nodes and metal sites in metal-organic frameworks

Photosensitisers for CO2 photoreduction: from metal complexes

to rylenes, an overview

π-Coordinated Arene Metal Complexes and Catalysis

Multiphoton and upconversion excitation of lanthanide(III) ions in

coordination complexesEdition: 1

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Specialist Periodical Reports

NanoscienceVolume 5

Edited by P. John Thomas and Neerish Revaprasadu



NanoscienceVolume 5

P John Thomas Bangor University, UK Neerish Revaprasadu University of Zululand, South Africa

SynopsisThe field of nanoscience continues to grow at an impressive rate and, with such a vast landscape of material, careful distillation of the most important discoveries will help researchers find the key information they require. Nanoscience Volume 5 provides a critical and comprehensive assessment of the most recent research and opinion from across the globe. Anyone practising in any nano-allied field, or wishing to enter the nano-world will benefit from this resource, presenting the current thought and applications of nanoscience.

Brief Contents

Series: Specialist Periodical Reports

ISSN: 2049-3541


ISBN: 9781788013710

Price: £314.95 | $441.00



Format: Hardback

Size: 234 x 156mm

Pages: 250

BIC: TBN, TGM

Nanostructured Materials for Supercapacitor Applications

Nanomedicine in sensing, delivery, imaging and tissue engineering:

Advances, opportunities and challenges

Nanoscale porphyrin superstructures: properties, self-assembly and

photocatalytic applications

Progress in single source precursors for layered 2D metal chalcogenide thin

films and nanomaterials

Plant Extracts Mediated Synthesis of Silver Nanoparticles For The Reduction

of Organic Dyes

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Food Chemistry, Function and Analysis

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Vitamin EChemistry and Nutritional Benefits

Edited by Etsuo Niki



Vitamin EChemistry and Nutritional Benefits

Etsuo Niki University of Tokyo, Japan

SynopsisThis book provides an overview of the state-of-the-art of the chemistry of vitamin E with regards to properties and functions and also nutritional benefits. It summarizes information on the role and activity of vitamin E, the current understanding of the advantages and limitations of vitamin E, and also its application in promotion of health and prevention of diseases. Based on sound, solid scientific evidence, this is a timely addition to the literature as the centennial anniversary of the discovery of this important vitamin approaches.

Brief Contents

Series: Food Chemistry, Function and Analysis

ISSN: 2398-0656


ISBN: 9781788012409

Price: £179.00 | $250.00



Format: Hardback

Size: 234 x 156mm

Pages: 242

BIC: MBNH3, PNF, PSB

General Chemistry: Structure, Function, and Action

Tocotrienol

Membrane Localization, Stabilization, Fluidity

Cellular Uptake of Tocopherols and Tocotrienols

alpha-Tocopherol Transfer Protein

alpha-Tocopherol Phosphate

alpha-Tocopherol Nicotinate

Oxidants and Antioxidants: Biological Oxidants

Lipid Oxidation

Antioxidant Action of Vitamin E

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advances in nucleic acid therapeutics · synthetic organic chemistry and the development of...

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