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www.cynosure.com 2007 Cynosure, Inc. Af rm is a trademark and Cynosure is a registered trademark of Cynosure, Inc.921-0378-000 Rev.1

Af rm TM: The Right DepthIdeal Wavelength1440 nm has a 2.0 - 2.5 higher af nity to water which is the target chromophore for treatingsuper cial wrinkles and overall skin rejuvenation.

What does this mean for you?

A wrinkle is a super cial phenomenon and not a deep phenomenon.

1540 nm and 1550 nm go deeper into tissue, beyond the zone of photoaged skin butnot quite deep enough to treat skin laxity; cooking healthy tissue will destroy healthytissue and replace it with healthy tissue.

Af rms 1440 nm directly targets the zone of photoaged skin - Treats what its supposedto treat!

Less pain with less energy.

Without the need for topical anesthesia or dyes you can signi cantly reduce treatmenttimes from 2 hours to 15 minutes!!

The Best Tec hno log yThe revolutionary Combined Apex Pulse SM

CAP = Combined Apex Pulse simultaneous collagen stimulation and remodeling.

(CAP) Technology, exclusive to Cynosure, isthe only technology that exists that combines varied levels of heat intensities withineach treatment pulse. The combination of high level an low level heat simultaneouslystimulates and remodels collagen to help ensure the wound healing process to happenmore quickly and effectively. (Because of the dual heating component, the Af rm doesnot need to go deeper than the zone of photoaged skin).

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BEFORE

AFTER

1 month Post 3 Tx

BEFORE

AFTER

6 months Post 5 Tx

The Top 10 Reasons Af rm TM: is Better!#1 The right depth!!

#2 Simultaneous collagen stimulation and remodeling

#3 No topical, gels or dyes

#4 Faster Tx

#5 Less Pain

#6 Fewer passes needed

#7 No downtime

#8 Less energy needed

#9 Great results

#10 Greater pattern density per 10 mm spot

The b ulk of solar da ma ge usually ocurs in a b and along the d ermis from 100m to 400m: therefore, a laser wave length tha t is ca pa ble of p ene trating to this de pth is op timal for wa ter-ba sed NSR. The 1.45m d iod e laser me ets the se c on ditions be c a use its op tica l pe n- etration d ep th is ab out 400m.

J Cosmetic & Laser Therapy 2002Christina A Hardaway, MD, et al.

In the a rea o f the w rinkles of the fa c e a nd ne c k, relat ively norma l-looking but irreg ularly run- ning elastic bres separated by large spaces were seen in the upper portion of the dermis.

British Journal of Dermatology 1986T.Tsuji, et al.

Peri-o ral Wrinkle Treatm ent

Micro-therma l Rejuvenation