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1 Copyright © 2014 Tata Consultancy Services Limited Affordable Sensing and Diagnosis for Healthcare Affordable Sensing and Diagnosis for Healthcare 10 th Sept2015 Dr. Arpan Pal Principal Scientist and Head, Innovation Labs, Kolkata Tata Consultancy Services Ltd. IBSS 2015

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Page 1: Affordable Sensing and Diagnosis for Healthcareibss2015.ieeebombay.org/wp-content/uploads/2015/10/d1s1t2.pdf · 4 Diagnosis from Symptoms and Signs is still an Art based on aggregate

1 Copyright © 2014 Tata Consultancy Services Limited

Affordable Sensing and Diagnosis for HealthcareAffordable Sensing and Diagnosis for Healthcare

10th Sept2015

Dr. Arpan PalPrincipal Scientist and Head, Innovation Labs, KolkataTata Consultancy Services Ltd.

IBSS 2015

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Click to edit Master title style

AgendaAgenda

Problems in Modern HealthcareProblems in Modern Healthcare

Technology Solutions Technology Solutions –– Internet of Things (Sensing and Internet of Things (Sensing and

Analytics)Analytics)

Example Scenarios Example Scenarios –– Coronary Artery Disease Detection Coronary Artery Disease Detection

and Stroke Patient Rehaband Stroke Patient Rehab

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Problems of the New Age and the New WorldProblems of the New Age and the New WorldProblems of the New Age and the New World

http://www.aoa.acl.gov/Aging_Statistics/index.aspx

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Diagnosis from Symptoms and Signs is still an Art based on aggregate rules -“Diagnosis is the heart of the medical art”

Data-driven systems allows Diagnosis to be Evidence-based than rulebased – allows personalization and adaptation

Diagnosis from Symptoms and Signs is still an Art based on aggregate rules -“Diagnosis is the heart of the medical art”

Data-driven systems allows Diagnosis to be Evidence-based than rulebased – allows personalization and adaptation

From Illness to Wellness and From Rule to EvidenceFrom Illness to Wellness and From Rule to EvidenceFrom Illness to Wellness and From Rule to Evidence

Need to go towards Wellness Driven ModelsAll stakeholders incentivized to keep patients healthy

Need to go towards Wellness Driven ModelsAll stakeholders incentivized to keep patients healthy

Illness Driven model incentivizes people being sick

“The health care system is really designed to reward you for being unhealthy. If you are a healthy person and

work hard to be healthy, there are no benefits.”- Mike Huckabee

Illness Driven model incentivizes people being sick

“The health care system is really designed to reward you for being unhealthy. If you are a healthy person and

work hard to be healthy, there are no benefits.”- Mike Huckabee

http://www.brainyquote.com/quotes/keywords/health_care.html#WmKeI72wL5Wg6wqG.99

http://www.greekmedicine.net/diagnosis/Introduction.html

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https://books.google.co.in/books?id=qW4IKSfM8x8C&pg=RA1-PA551&lpg=RA1-PA551&dq=from+symptoms+to+diagnosis+art+or+science&source=bl&ots=UHqeP9eJev&sig=9E5_SjS_Bj48XHvT71KzbH6Gsyw&hl=en&sa=X&ved=0CEoQ6AEwBmoVChMIt-jptLUxwIVg0mOCh14GQ_a#v=onepage&q=from%20symptoms%20to%20diagnosis%20art%20or%20science&f=false

From  Signs and Symptoms to Diagnosis of DiseaseFrom  Signs and Symptoms to Diagnosis of DiseaseFrom  Signs and Symptoms to Diagnosis of Disease

Affordable SensingAffordable SensingAffordable Sensing

Affordable Sensing

Affordable Affordable SensingSensing Sensor Data

AnalyticsSensor Data Sensor Data

AnalyticsAnalytics

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Internet‐of‐Things based Remote  Sensing and Analytics SystemInternetInternet‐‐ofof‐‐Things based Remote  Sensing and Analytics SystemThings based Remote  Sensing and Analytics System

Mobile phone asmedical gateway

TCS Connected Universe Platform

Web Request

PatientRecords

SocialNetwork

HealthcarePortal

Expert DoctorMobiles Wearables

Nearables – Camera, 3D, Thermal, …..

Instruments

• Real‐time View• Alerts for Medical Emergency • Analytics for Diagnostics / Prognostics

Rural Remote Healthcare –Villages in Chhattisgarh, GujaratHome Monitoring –Hospital in BangaloreElderly People Monitoring –Pilot at Singapore

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Data‐driven Healthcare ‐ TrendsDataData‐‐driven Healthcare driven Healthcare ‐‐ TrendsTrends

http://hitconsultant.net/2015/03/16/infographic-sxsw-health-tech-trends/

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Physiological Sensing on MobilePhysiological Sensing on MobilePhysiological Sensing on Mobile

Solution Accuracy

Heart Rate in Mobile ~2 bpm

Blood Pressure 92% in healthy subjects, 85% in patients

HRV (SDNN) 89%

Activity Classification (Walking, Brisk Walking, Jogging)

80%

Fall Detection 92% with reduced false alarms

Step Count 95%

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Physiological Sensing on WearablePhysiological Sensing on WearablePhysiological Sensing on Wearable

Heart Rate, BP, Heart Rate, BP, HRVHRV , SpO2, Respiratory Rate, SpO2, Respiratory Rate

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Signal Processing ChallengesSignal Processing ChallengesSignal Processing Challenges

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Mobiles Wearables

Nearables – Camera, 3D, Thermal, …..

Disease Detection and Control• Chronic / Elderly Patient @Home• Heart Patient @Home / Hospital• Villagers @ Rural Health center

Care GiverDoctor @ Hospital

Solution ArchitectureSolution ArchitectureSolution Architecture

• Coronary Artery Disease• Stroke Rehab

Instruments

Prevent Disease, Promote Wellness, InclusivePrevent Disease, Promote Wellness, InclusivePrevent Disease, Promote Wellness, Inclusive

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Use case ‐ Early Detection of Coronary Artery Disease (CAD)Use case Use case ‐‐ Early Detection of Coronary Artery Disease (CAD)Early Detection of Coronary Artery Disease (CAD)

y 2020, CAD will be the leading cause of death in Western and Asian countries 20-30% deaths in industrialized countries, 60% of world heart ailments from IndiaCAD is a modern epidemic according to WHOCurrent method of 3D Angiography costly, obtrusive and harmful to health

y 2020, CAD will be the leading cause of death in Western and Asian countries 20-30% deaths in industrialized countries, 60% of world heart ailments from IndiaCAD is a modern epidemic according to WHOCurrent method of 3D Angiography costly, obtrusive and harmful to health

Working with doctors at a Cardiac Specialty Hospital in KolkataWorking with doctors at a Cardiac Specialty Hospital in Kolkata

Sensor based System Sensor based System –– Blood Pressure, Heart Rate, Blood Oxygen from Wearable / MobileBlood Pressure, Heart Rate, Blood Oxygen from Wearable / Mobile

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Cognitive Computing and AI – the FutureCognitive Computing and AI Cognitive Computing and AI –– the Futurethe Future

Deep LearningDeep LearningDeep QADeep QA

tp://www.cbsnews.com/news/jeopardy-winning-computer-now-using-its-brain-for-ience/

http://www.slate.com/blogs/future_tense/2012/06/27/google_computers_learnidentify_cats_on_youtube_in_artificial_intelligence_study.html

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Alerting and Prognosis for CADAlerting and Prognosis for CADAlerting and Prognosis for CAD

Live Patient Data (Sensing) Stored Medical Records

Knowledge Base

Reasoning

Alert Generation

Healthcare Portals, Medical Books, Article

Diagnostic / Prognostic Support

Relevant Data

Evidence based Learning Text Mining

Knowledge Access

Stream Handling

Anomaly Detection

Other Filters

Deductive Abductive Others

EntitiesRules

Relations

vailable Dataset – MIMIC-II– Waveform for 2500 patients matched with medical records - HR, BP, RR, SpO2– Classified into approx. 700 CAD and 1200 non-CAD patients using ICD-9 codes

Working with doctor at a Cardiac Specialty Hospital in KolkataWorking with doctor at a Cardiac Specialty Hospital in Kolkata

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Use Case ‐ Tele‐Rehabilitation for Stroke PatientsUse Case Use Case ‐‐ TeleTele‐‐Rehabilitation for Stroke PatientsRehabilitation for Stroke Patients

nnual cost in EURO in European conomy: - twice the cost of cancer

798 billion798 billionpeople worldwide needrehabilitation services

do not receive rehabilitationtreatment after discharge

2/32/31 billion1 billion

abWeek conference 2015 by NeuroAtHome (http://www.neuroathome.net/p/home.html)

• Existing Quantitative Gait Analysis systems (Goniometers, markers, VICON system) costs approx. $200K & not readily available in the market. Expensive maintenance costs

• Difficult for patients to frequently visit hospitals

• Existing Quantitative Gait Analysis systems (Goniometers, markers, VICON system) costs approx. $200K & not readily available in the market. Expensive maintenance costs

• Difficult for patients to frequently visit hospitals

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Low cost, affordable for home use

Ease of Access

Fun @ Exercise

Improved Outcome

Affordableand

Reliable

Proposed Kinect based SolutionProposed Kinect based SolutionProposed Kinect based Solution

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Solution ArchitectureSolution ArchitectureSolution Architecture

Left Heel: Line of Progression Right Heel: Line of Progression

Store Raw Data

Patient’s Exercise

Parameter

Patient History

Extract Parameters

Working with doctor at a Neuro-Speciality Hospital in KolkataWorking with doctor at a Neuro-Speciality Hospital in Kolkata

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PublicationsPublicationsPublications

Arpan Pal, Aishwarya Visvanathan, Aniruddha Sinha, Anirban Duttachoudhury, Tanushyam Chattopadhyay,  "A Robust Heart Rate Detection usSmart‐phone Video", in MobileHealth workshop of Mobihoc 2013Avik  Ghose,  Amit  Agrawal,  Priyanka  Sinha,  Anirban  Duttachoudhury,  Chirabrata  Bhaumik,  Aniruddha  Sinha,  “UbiHeld  ‐ Ubiquitous  HealthcMonitoring System for Elderly and Chronic Patient”, in Recognize2Interact Workshop of UbiComp 2013Avik  Ghose,  Vivek  Chandel,  Anirban  Duttachoudhury,  Chirabrata  Bhaumik,  “AcTrak  ‐ Unobtrusive  Activity  Detection  and  Step  Counting  usSmartphones”, Mobiquitous 2013Anirban Duttachoudhury, Aishwarya Visvanathan,  Rohan  Banerjee, Aniruddha  Sinha, Arpan  Pal,  Chirabatra  Bhaumik, Anurag  Kumar,  "DeAbstract: HeartSense – Estimating Blood Pressure and ECG from Photoplethysmograph using Smart Phones", SenSys 2013, Italy, Rome. 11‐15 N2013Arpan Pal, Aishwarya Visvanathan, Anirban Dutta Choudhury,  and Aniruddha  Sinha.  2014.  Improved heart  rate  detection  using  smart  phoneProceedings of the 29th Annual ACM Symposium on Applied Computing (ACM‐SAC), pp. 8‐13Rohan  Banerjee,  Aniruddha  Sinha,  Anirban  Dutta  Choudhury,  Aishwarya  Visvanathan,  "PhotoECG:  Photoplethysmography  to  Estimate  EParameters", ICASSP 2014Aishwarya Visvanathan, Rohan Banerjee, Anirban Duttachoudhury, Aniruddha Sinha, "Smart Phone Based Blood Pressure Indicator", in MobileHeaworkshop of Mobihoc 2014 11‐Aug, 2014, Philadelphia, PA, USA.Rohan Banerjee, Anirban Duttachoudhury, Aniruddha Sinha,  "Estimating Blood Pressure using Windkessel Model on Photoplethysmogram", 3Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC '14), Chicago, Illinois, USA on August 26‐30, 2014.Aishwarya Visvanathan, Rohan Banerjee, Aditi Misra, Anirban Dutta Choudhury and Arpan Pal, "Effects of Fingertip Orientation and Flash LocationSmartphone Photoplethysmography", Third  International Workshop on Recent Advances  in Medical  Informatics  (RAMI‐2014),  ICACCI 24‐27  Se2014, Delhi.

0) "HeartSense: Estimating Heart rate from Smartphone Photoplethysmogram using Adaptive Filter and Interpolation"  in 1st International Confereon IoT Technologies for HealthCare (HealthyIoT, IoT‐360), 2014

1) Banerjee,  Rohan  et  al.  "Demo  Abstract:  HeartSense:  Smart  Phones  to  Estimate  Blood  Pressure  from  Photoplethysmography"  in  11th  AConference on Embedded Networked Sensor Systems (SenSys 2014) – Best Demo Award

2) Banerjee, Rohan et al. "HeartSense: Photoplethysmography to Estimate Physiological Vitals" in The 4th International Conference on the InternetThings, 2014

3) Banerjee, Rohan et al. "Noise Cleaning and Gaussian Modeling of Smart Phone Photoplethysmogram  to  improve Blood Pressure EstimatioPresented in ICASSP 2015

4)MISRA Aditi et al., “Novel Peak detection to estimate HRV using Smartphone Audio”, presented in Body Sensor Network (BSN) 2015 5) Nasim Ahmed et al. “Feasibility Analysis for Estimation of Blood Pressure and Heart Rate using A Smart Eye Wear”, Wearable workshop in Mobi2015

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PatentsPatentsPatents

1) Vivek Chandel, Anirban Dutta Choudhury “ACCELERATION‐BASED STEP ACTIVITY DETECTION AND CLASSIFICATION ON MOBILE DEVICES” IndiaComplete Specification 1875/MUM/2013 on 3‐April‐2013

2) Arpan Pal, Aniruddha Sinha, Aishwarya Visvanathan, Anirban Dutta Choudhury, Tanushyam Chattopadhyay, "MEASUREMENT OF PHYSIOLOGICAPARAMETERS", Indian Complete specification 2489/MUM/2013 on 26‐July 2013

3) VISVANATHAN, Aishwarya;  SINHA,  Aniruddha;  PAL,  Arpan;  BANERJEE,  Rohan,  "MONITORING  PHYSIOLOGICAL  PARAMETERS",  Indian  Complespecification 3152/MUM/2013 on 3‐Oct 2013

4) VISVANATHAN,  Aishwarya;  SINHA,  Aniruddha;  PAL,  Arpan;  BANERJEE,  Rohan;  DUTTA  CHOUDHURY,  Anirban,  "MONITORING  PHYSIOLOGICAPARAMETERS", Indian Complete Specification 1540/MUM/2014 on 2‐May 2014

5) ROHAN  BANERJEE,  Anirban  Dutta  Choudhury,  ANIRUDDHA  SINHA,  "MEASURING  BLOOD  PRESSURE",  Indian  complete  Application  N2593/MUM/2014, Filing Date : 11‐Aug 2014

6) VISVANATHAN, Aishwarya et al., “Region of Interest based PPG enhancement of smartphone video”, Provisional Specification 3396/MUM/20147) BANERJEE, Rohan et al., Noise Cleaning of Smart Phone PPG signal to estimate Blood Pressure”, Indian complete Application No. 1684/MUM/2018) MISRA Aditi et  al.,  “A  System  and Method  for estimating heart  rate  and heart  rate  variability using heart  sounds  collected  from  smartphon

microphones using envelope detection”, Indian Patent Application No. 1544/MUM/2015

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