airway complicationshemodynamic disturbancesventilator associated lung injury: vilioxygen...
TRANSCRIPT
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Nursing Role in Preventing complications of MV
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Outline
Airway complications
Hemodynamic disturbances
Ventilator associated lung injury: VILI
Oxygen toxicity
Ventilator associated pneumonia
Pulmonary emboli
Patient ventilator asynchrony
Sleep disturbance
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Outline
Airway complications
Hemodynamic disturbances
Ventilator associated lung injury: VILI
Oxygen toxicity
Ventilator associated pneumonia
Pulmonary emboli
Patient ventilator asynchrony
Sleep disturbance
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Injuries to mouth, lips and oropharynx
Trauma to the lips and cheeks from tube ties
Avulsion of skin due to adhesive tape
Injuries to the entrapped tongue
Pressure ulcers to the palate and oropharynx
Perioral herpes
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Skin flap avulsion during extubation due to adhesive tape.
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Endotracheal Tube Fixator
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Slipped ETT
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Chest X-Ray
3-4 cm
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Correct ET Tube Placement
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Correct ET Tube Placement
Secure ET tube in place, note the numberSedate patient with appropriate MAASAvoid accidental, or self extubation
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Laryngeal Inguries
Laceration and hematoma in the left vocal fold during direct laryngoscopy. Exam performed with rigid telescope
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Laryngeal Injuries
Bilateral intubation granulomas inserted in the vocal apophasis.
Exam performed with rigid telescope.
Ulcerated lesion in the posterior glottic commissure soon after extubation. Exam performed
with rigid telescope.
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Laryngeal Injuries
diffuse posterior erythema, edema and piled-up mucosa of inter-arytenoid area
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Cuff Related Injuries
Risk of aspirationRisk of mechanical complications
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Prince J S et al. Radiographics 2002;22:S215-S230
Postintubation stenosis
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Tracheal and Glottic Stenosis
Tracheal stenosis (exam performed with flexible nasofibroscope)
Glottic stenosis (exam performed with rigid telescope).
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Ulceration of the mucosa and cartilage, granulation tissue, and fibrous tissue
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Tracheomalacia
Tracheal collapse of more than 50% during expiration is diagnostic of tracheomalacia
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AnapnoGuard
The AnapnoGuard system detects air leakage from the lungs by measuring the CO2 level above the cuff. Detection of high CO2 levels above the cuff represents leakage
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Sphygmomanometers
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Minimum Leak Volume Technique
Air inflation of the tube cuff until the airflow heard escaping around the cuff during positive pressure breath ceases.
Place a stethoscope over larynx. Indirectly assesses inflation of cuff.
Slowly withdraw air (in 0.1-mL increments) until a small leak is heard on inspiration.
Remove syringe tip, check inflation of pilot balloon
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Outline
Airway complications
Hemodynamic disturbances
Ventilator associated lung injury: VILI
Oxygen toxicity
Ventilator associated pneumonia
Pulmonary emboli
Patient ventilator asynchrony
Sleep disturbance
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Case Scenario
64 year old male with history of COPD who presented with severe respiratory distress and required to be intubated and placed on CMV, VT of 650 ml and a rate of 24/min.
Immediately post intubation, his systolic blood pressure dropped from 132 mm Hg to 73 mm Hg.
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Hypotension following MV
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PPV vs. Spontaneous Ventilation
0
5
3
-3
120
0
10
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0
5
3
-3
110
0
8
PPV vs. Spontaneous Ventilation
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Effect of Lung Volume on Venous Return
No effect in Normal individual with PEEP less than 10 cmH2O
Major effect in patients with Dynamic Hyperinflation such as asthma and COPD, and in pre-existing pulmonary hypertension
Small changes in PVR can cause considerable hemodynamic compromise secondary to acute increase in PVR
Avoid air trapping in these patients
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Symptoms of hemodynamic effects
Decreased cardiac output, decreased venous return
Observe for:▪ Decreased BP▪ Restlessness, decreased LOC▪ Decreased urine output▪ Decreased peripheral pulses▪ Slow capillary refill▪ Increasing Tachycardia
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Outline
Airway complications
Hemodynamic disturbances
Ventilator associated lung injury: VILI
Oxygen toxicity
Ventilator associated pneumonia
Pulmonary emboli
Patient ventilator asynchrony
Sleep disturbance
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Ventilator-associated lung injury (VALI)
•Overdistention Volutrauma
•Repeated recruitment and collapse
Atelectetrauma
•Inflammatory mediatorsBio trauma
•High-pressure induced lung damageBarotrauma
•FiO2Oxygen toxic effect
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Ventilation-Induced Lung Injury (VILI)Atelectrauma:
Repetitive alveolar collapse and
reopening of the under-recruited
alveoli
Volutrauma:Over-distension of
normally aerated alveoli due to excessive volume
delivery
*Dreyfuss: J Appl Physiol 1992
Cytokines, complement, prostanoids, leukotrienes, O2
- Proteases
Biotrauma
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Pinsp = 40 mbar
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Recognized Mechanisms of Airspace Injury
“Stretch”
“Shear”
Airway Trauma
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Gas Extravasation Barotrauma
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Barotrauma
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Barotrauma
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Barotrauma
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Volume
Pressure
Zone ofOverdistention
“Safe”Window
Zone ofDerecruitmentand Atelectasis
Injury
Injury
Optimized Lung Volume “Safe Window”
Overdistension Edema fluid accumulation Surfactant degradation High oxygen exposure Mechanical disruption
Derecruitment, Atelectasis Repeated closure / re-
expansion Stimulation inflammatory
response Inhibition surfactant Local hypoxemia Compensatory
overexpansion
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Diseased Lungs Do Not Fully Collapse,Despite Tension Pneumothorax
And they cannot always be fully “opened”
Dimensions of a fully Collapsed Normal Lung
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Outline
Airway complications
Hemodynamic disturbances
Ventilator associated lung injury: VILI
Oxygen toxicity
Ventilator associated pneumonia
Pulmonary emboli
Patient ventilator asynchrony
Sleep disturbance
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Oxygen Toxicity : FIO2 > 60 % for > 24h
Absorptive atelectasis O2/N2 = 21/79
>>>>>> 50/50 Accentuation of
hypercapnia Chronic respiratory
failure: PCO2 with PO2
Damage to airways Bronchopulmonary
dysplasia Diffuse alveolar
damage
Carbon dioxide
Water vapour
Oxygen
Nitrogen
2A2A2A2A NPOHPCOPOPpressureAlveolar
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Diffuse Alveolar Damage
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Oxygen toxicity Reduce FiO2?
PEEP Alveolar recruitment maneuvers Alternative modes of ventilation
Inverse-ratio , APRV, HFV, ….. Inhaled nitric oxide (iNO) Extracorporeal membrane oxygenation (ECMO) Diuresis
if pulmonary edema is possible Bronchopulmonary hygiene
if secretions are prominent Augmentation of antioxidants??
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Outline
Airway complications
Hemodynamic disturbances
Ventilator associated lung injury: VILI
Oxygen toxicity
Ventilator associated pneumonia
Pulmonary emboli
Patient ventilator asynchrony
Sleep disturbance
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Path to VAP
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Ventilator Associated Pneumonia: Definitions
VAP – ventilator associated pneumonia >48 hours on vent Combination of:
▪ CXR changes▪ Sputum changes▪ Fever, ↑ WBC▪ positive sputum culture
Occurs secondary to micro-aspiration of upper airway secretions
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Risk Factors for VAP
No 1 risk factor is endotracheal intubation Factors that related to cross contamination:
Poor adherence to infection control standards Factors that enhance colonization of the oropharynx
&/or stomach: Poor oral hygiene
Conditions favoring aspiration into the respiratory tract or reflux from GI tract: Supine position NGT placement Re-Intubation and self-extubation Surgery of head/neck/thorax/upper abdomen GERD Coma/ depressed Glascow coma scale
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Chest X-Ray: VAP
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Prevent Contamination: Hand Wash
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Prevent Contamination: Hand Wash
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Prevent Contamination: Personal Protective Equipments
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Prevent Contamination: Change gloves when changing from contaminated to clean area
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Prevent Contamination: Environmental Cleaning
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Prevent Contamination: Use closed inline system for MDIs
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Prevent Contamination: Use condensate traps
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Prevent Contamination: Chnage HME every 48 hrs
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Reduce Colonization: Oral Hygien, frequent tooth brushing
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Reduce Colonization: Oral Hygien mouth swabbing with chlorhexidine
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Reduce Colonization: Oral Hygien suctioning of oral secretion
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Prevent Colonization: Closed suction system
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Prevent Colonized Circuits: Changed when visibly soiled
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Prevent Colonization: Periodically drain the condensate
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Prevent Aspiration: Head of Bed 40 degrees
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Prevent Aspiration: HOB Elevation
HOB at 30-45º
CDC Guideline for Prevention of Healthcare Associated Pneumonias 2004 ATS / IDSA Guidelines for VAP
2005
45o head-up tilt is the goal in all patients unless contraindicated
No benefit of semi-recumbency ~30o over standard care ~10o
Supine position is harmful
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Prevent Aspiration: Measure cuff pressure 20-25 mm Hg
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Prevent Aspiration: Subglottic suctioning
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VAP prevention :VAP Bundle
Elevation of the head of the bed 30-45o Use 15-30o for neonates and small
infants, otherwise 30-45o Daily sedation vacations (minimize
duration of intubation) Daily assessment of readiness to
extubate Peptic ulcer disease (PUD)
prophylaxis Oral care protocol (chlorhexidine) DVT prophylaxis option
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HOB Elevation Leads to Significant reduction in VAP
0
5
10
15
20
25
% V
AP
Supine HOB Elevation
Dravulovic et al. Lancet 1999;354:1851-1858
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Does the VAP bundle work in real life
CCU VAP Bundle Compliance Vs Infection Rate
0
5
10
15
20
25
30
35
40
Oct
-06
No
v-06
Dec
-06
Jan
-07
Feb
-07
Mar
-07
Ap
r-07
May
-07
Jun
-07
Jul-
07
Au
g-0
7
Sep
-07
Oct
-07
No
v-07
Dec
-07
Jan
-08
Feb
-08
0%
20%
40%
60%
80%
100%
VAP Infection Rate VAP Bundle Compliance%
Linear (VAP Infection Rate) Linear (VAP Bundle Compliance%)
NHSN 50th Percentile 4.1NHSN 50th
Percentile 4.1
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Outline
Airway complications
Hemodynamic disturbances
Ventilator associated lung injury: VILI
Oxygen toxicity
Ventilator associated pneumonia
Pulmonary emboli
Patient ventilator asynchrony
Sleep disturbance
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Pulmonary Embolism
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Bilateral pulmonary embolism
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VAP prevention :VAP Bundle
Elevation of the head of the bed 30-45o Use 15-30o for neonates and small
infants, otherwise 30-45o Daily sedation vacations (minimize
duration of intubation) Daily assessment of readiness to
extubate Peptic ulcer disease (PUD)
prophylaxis Oral care protocol (chlorhexidine) DVT prophylaxis option
![Page 77: Airway complicationsHemodynamic disturbancesVentilator associated lung injury: VILIOxygen toxicityVentilator associated pneumoniaPulmonary emboliPatient](https://reader036.vdocument.in/reader036/viewer/2022062803/56649c7f5503460f949364dd/html5/thumbnails/77.jpg)
Outline
Airway complications
Hemodynamic disturbances
Ventilator associated lung injury: VILI
Oxygen toxicity
Ventilator associated pneumonia
Pulmonary emboli
Patient ventilator asynchrony
Sleep disturbance
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Asynchrony with the ventiaitor
Fighting the ventilators Inconsistent tidal volume Increase work of breathing Barotraumas and thoracic air leak Insufficient gas exchange Disturbances in the cerebral blood
flow
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Outline
Airway complications
Hemodynamic disturbances
Ventilator associated lung injury: VILI
Oxygen toxicity
Ventilator associated pneumonia
Pulmonary emboli
Patient ventilator asynchrony
Sleep disturbance
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0
100
200
300
100
Stage 1
Stage 2
Stage 3
Stage 4
REM
Non R
EM
Age 40
Age 40
MV
Sle
ep T
ime (
min
ute
s)
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8 10
12
14
16
18
20
22
0 2 4 6 8
Stage 1
Stage 2
Stage 3
Stage 4
REM
Normal Sleep Pattern
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8 10
12
14
16
18
20
22
0 2 4 6 8
Stage 1
Stage 2
Stage 3
Stage 4
REM
Hyponogram for a Patient on Mechanical Ventilation
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Mechanisms by which mechanical Ventilation Disrupt Sleep
Noise disruption Ventilator alarm:
▪ inappropriate threshold▪ Delayed alarm inactivation
Humidifier alarms Disruption by nursing interventions
Airway suction Nebulizer delivery
Ventilation-related pharmacological disruption Benzodiazepines (↓REM, ↓deep NREM) Opioids (↓REM, ↓deep NREM) Neuromuscular blocking drugs
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والوضعياتاإلنذارات
. P مكتومًا اإلنذار نظًام تبِق[ ال كًان أو سببه تعلم كنت لو حتى اإلنذار تتجًاهل ال
. P مهمًا P شيئًا ليس
وضعية في المريض لوضعية ضع فولر مشًابهةأخفض وتسهيل منهًاأو المريض راحة لزيًادة
التنفس.
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Thank you
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