alabama brief cognitive screener (abcs)
DESCRIPTION
They’re impaired, what now? Screening labs for reversible causes: CBC Electrolytes, glucose, kidney function, liver function thyroid function vitamin B12 level Notably absent: syphilis screening unless they have a specific risk factorTRANSCRIPT
Alabama Brief Cognitive Screener (ABCs) Theyre impaired, what
now?
Screening labs for reversible causes: CBC Electrolytes, glucose,
kidney function, liver function thyroid function vitamin B12 level
Notably absent: syphilis screening unless they have a specific risk
factor Rule out cerebrovascular disease
Neuroimaging Structural Neuroimaging is appropriate to detect
lesions thatmay result in cognitive impairment * Rule out
cerebrovascular disease detect segmental atrophy of
neurodegenerative syndromes * Practice Parameter: Diagnosis of
Dementia (Knopman et al, Neurology 2001:56: ) What is segmental
atrophy?
Duara et al, Neurology 2008:71: Most Common Cause of Dementia Aging
and Preclinical Alzheimers disease
Sperling et al.Alzheimers and Dementia, 2011;7: Mild Cognitive
Impairment due to Alzheimers disease
Biomarker evidence of A deposition (by PET or CSF) OR Evidence of
Neuronal injury (MRI, CSF, or FDG-PET) NIA-AA criteria, 2011
Dementia due to Alzheimers disease-
Insidious onset Clear-cut history of worsening of cognition
Amnestic: most common, impaired learning and recall of
recentlylearned information AND 1 other cognitive domain
Nonamnestic: Language presentation: most prominent Visuospatial
presentation: spatial cognition, including objectagnosia, impaired
face recognition, simultanagnosia, and alexia. Executive
dysfunction: impaired reasoning, judgment, and problemsolving.
NIA-AA 2011 Criteria DSM-V Criteria for Major Neurocognitive
Disorder Due to Alzheimers Disease
insidious onset & gradual progression 2 cognitive domains
Probable- either: genetic mutation (fmh or test) 1) decline in
memory & 1 other cognitive domain, AND 2) steady progression,
AND 3) no evidence of mixed etiology Diagnostic and Statistical
Manual of Mental Disorders, Fifth Edition, AmericanPsychiatric
Association, 2013.