Alan David Hutson Address Department of Biostatistics and Bioinformatics Roswell Park Cancer Institute Elm & Carlton Streets Buffalo, NY 14263-0001 work: (716) 845-2300 ext 5594, home: (716) 689-9348 email: alan.hutson@roswellpark.org Education Ph.D. Statistics; 7/96, University of Rochester M.A. Statistics; 2/93, University of Rochester M.A. Statistics; 5/90, State University of New York at Buffalo B.A. Statistics; 5/88, State University of New York at Buffalo 2 years towards EE degree; 9/83-5/85, University of New Hampshire KL2 Mentor Training Program 2016 Experience Roswell Park Cancer Institute, Department of Biostatistics and Bioinformatics August 2005- present. Chair. The Department currently has 4 major divisions (biostatistics, bioinformatics, R-bioconductor project and biomedical informatics) and is focused on supporting research in finding a cure for and preventing cancer. NRG Oncology SDMC Deputy Group Statistician October 2016-. Roswell Park Cancer Institute March 2017 – September 2017 Interim Director of Clinical Data Network Resource for the Core Cancer Center Grant. Roswell Park Cancer Institute August 2010 – August 2012, March 2016-July2016 Associate Director of Biostatistics Resource for the Core Cancer Center Grant. Roswell Park Cancer Institute April 2016 – Director PDT P01 Biostatistics Core. Roswell Park Cancer Institute August 2014 – Co-Director Ovarian SPORE Biostatistics and Biomedical Informatics Core. Roswell Park Cancer Institute, Department of Biostatistics

2

August 2007- present. Professor of Oncology. State University of New York at Buffalo, Department of Biostatistics, May 2016-. Research Professor. State University of New York at Buffalo, Director of the CTSA BERD Core (2015-2016). Responsible for providing statistical support and statistical methods development to the CTSA. State University of New York at Buffalo, Department of Biostatistics, June 2003 – March 2016. Chair. Founding chair of the department. Initiated MA and PhD program in Biostatistics. Initiated MS in Bioinformatics and Biostatistics. Initiated Minor in Statistics. Initiated certificate programs in Applied Biostatistics and Statistical Informatics. Roswell Park Cancer Institute August 2005 - August 2010. Director of Biostatistics Resource for the Core Cancer Center Grant. State University of New York at Buffalo, Department of Biostatistics, August 2007 – May 2016. Professor. State University of New York at Buffalo, Department of Biostatistics, June 2003 – August 2007. Associate Professor. State University of New York at Buffalo, Department of Pharmacy, April 2005 – August 2007. Research Associate Professor. State University of New York at Buffalo, Department of Biostatistics, June 2003 – August 2007. Director of Undergraduate Studies. State University of New York at Buffalo, Department of Social and Preventive Medicine, June 2002 – June 2003. Chief, Division of Biostatistics. State University of New York at Buffalo, Department of Social and Preventive Medicine, June 2002 – June 2003. Associate Professor. University of Florida, Department of Statistics, July 2001 - February 2002. Associate Director,

Division of Biostatistics. The division consists of 12 faculty and over 20 staff members. Responsibilities include managing the division's budget and staff.

University of Florida, Department of Statistics, July 1996 - May 2002. Director of the GCRC Informatics Core (responsible for the statistical components of approximately

50-70 active clinical trial protocols in a given year). Other duties include mentoring graduate statistics and medical students who intern on the GCRC and managing informatics staff.

3

University of Florida, Department of Statistics, September 2001 - May 2002. Assistant Professor (awarded tenure and promotion to Associate Professor April 2002). Primary duties involve supporting clinical trials research. Teaching duties include graduate level biostatistics courses and short courses for medical researchers and students. University of Florida, Center for Biostatistics & Epidemiology, June 2000 - May 2002. Director. The work of the center includes directing data coordinating centers, developing software for internet data capture, and statistical support of clinical trials. University of Florida, Department of Statistics, March 1999 - May 2002. Director of the Biostatistics Coordinating Center for the DCA-MELAS phase III clinical trial. University of Florida, Department of Statistics, July 1996 - January 2002. Director of the Biostatistics Coordinating Center for the DCA-CLA phase III clinical trial. University of Florida, Department of Statistics, July 1996 - September 2001. Research Assistant Professor. University of Florida, Department of Statistics, May 2000 - July 2001. Interim Director, Division of Biostatistics. University of Florida, Department of Statistics, July 1996 - July 1999. Director of the Biostatistics Coordinating Center for the DCA-MALA phase III clinical trial. University of Rochester, Department of Statistics, Summer 1994 - Fall 1995. Instructor of “Applied Statistics for the Social Sciences” four times. Class sizes ranged from 130 to 170 students. University of Rochester, Department of Biostatistics, August 1992 - July 1996. Research trainee

supported by NIH Environmental Health Science Training Grant. Consultant on various statistical projects. Also served as teaching assistant in courses for biomedical students and research fellows.

University of Rochester, Department of Community and Preventative Medicine, Summer 1992. Worked with the department chair on simulation projects related to the investigation of ROC curves. The work resulted in one joint publication. Also developed Monte Carlo simulation programs for social economics study. University of Rochester, Department of Statistics, Fall and Spring 1991-1992. Teaching assistant for introductory statistics courses. Otsuka America Pharmaceuticals, Inc., Rockville, MD, June 1990 - August 1991. Biostatistician. Assisted in the development of phase I and phase II protocols for infectious

diseases and psychopharmacology therapeutic groups. Performed statistical analysis in preparation of NDA for cardiology therapeutic group.

4

Roswell Park Memorial Institute, Buffalo, NY, summer 1989. Research apprentice in the Biomathematics Department. Worked on customizing SAS and Fortran graphics routines

in trying to better represent three dimensional dose response surfaces. Also worked on non-linear dose response curve fitting.

State University of New York at Buffalo, Fall and Spring 1988-1990. Teaching assistant for

SAS statistical computing course and introductory statistical courses (graduate and undergraduate).

Awards 2013 Inducted into Delta Omega Public Health Honor Society, Gamma Lambda Chapter (inaugural selection) 2011 Elected Fellow of the American Statistical Association 2010 School of Public Health and Health Professions Outstanding Senior Researcher 2004 School of Public Health and Health Professions Dean’s Award 2001 NYSTAR Distinguished Professor with recognized excellence in bioinformatics

Who's Who in Health Sciences Education (WWHSE) Bonus Pay Award (1998-99), University of Florida Awarded UF CLAS Research Initiation Project (1997) Environmental Health Sciences Training Grant (4 years) NIH T32 E507271 Various tuition scholarships, Regents scholarship Scholar Athlete (SUNY Buffalo) Professional Affiliations

Member American Statistical Association (Fellow), Institute for Mathematical Statistics, American Public Health Association, Society for Controlled Clinical Trials

President-elect 01-02 for the Association of GCRC Statisticians Editorial Boards Current Communication in Statistics – Theory and Methods, Associate Editor

5

Communication in Statistics – Simulation and Computation, Associate Editor Communication in Statistics – Case Studies, Data Analysis and Applications, Associate Editor Sri Lankan Journal of Applied Statistics, Associate Editor Completed Journal of Surgical Oncology, Associate Editor Mathematical Reviews, Technical Reviewer Journal of Statistical Planning and Inference, Associate Editor for the S.N. Roy Centennial Volume External Program Review Committees

1. Medical College of Wisconsin, Division of Biostatistics Masters Project

“New Measures of Process Capability for use in Statistical Quality Control.” The project resulted in a 30 page paper: White, D. B. and Hutson, A. D. (1990) Robust and Comprehensive Monetary Metrics for Process Capability, which was later presented as an ASA poster session.

Ph.D. Thesis “Estimation of Quantile Functions and Applications” Advisor: Govind S. Mudholkar Books

1. Vexler, A., Hutson, A. and Chen, X. (2016) Statistical Testing Strategies in the Health Sciences. Chapman and Hall/CRC, New York.

2. Vexler, A. and Hutson, A. (2017) Statistics in the Health Sciences: Theory, Applications, and Computing. Chapman and Hall/CRC, New York. (in submission)

Book Reviews

1. Hutson, A. D. (2004) Book Review: Resampling Methods for Dependent Data, by S. N. Lahiri, New York, Springer-Verlag, 2003, ISBN 0-387-00928-0, xiv + 374 pp, $79.95. Technometrics.

2. Hutson, A. D. (2012) Book Review: Genomic Clinical Trials and Predictive Medicine by Richard M. Simon, New York, Cambridge University Press, 2013, ISBN 978-107-00880-9. Technometrics.

6

Encyclopedia Entries 1. Shan, G., Wilding, G.E. and Hutson, A. D. (2017) Computationally Intensive Two-Stage

Designs for Clinical Trials. Wiley StatsRef: Statistics Reference Online. Wiley, New York, NY. (in press)

2. Shan, G.and Hutson, A. D. (2017) Tests for comparing two ordered multinomials. Wiley StatsRef: Statistics Reference Online. Wiley, New York, NY. (in press)

3. Vexler, A., Yu, J. and Hutson, A. (2014) “Empirical likelihood methods in clinical experiments”, Methods and Applications of Statistics in Clinical Trials, Volume 2: Planning, Analysis, and Inferential Methods. Wiley, New York, NY. Pages 146-165.

4. Hutson, A. D. and Brady, M. (2010) “Clinical Trial”, Encyclopedia of Research Design. SAGE. Thousand Oaks, CA

Book Chapters

1. Asubonteng, K., Mudhokar, G. S. and Hutson, A. D. (2017) “A Transformation for the Analysis of Unimodal Hazard Rate Lifetime Data”, Mathematical and Statistical Applications in Life Sciences and Engineering. Springer-Verlag, New York. (in press)

2. Hutson, A. D. (2013) “SUNY at Buffalo Department of Statistics”, Strength in Numbers: The Rising of Academic Statistics Departments in the U. S. Springer-Verlag, New York.

3. Brady, M. F., Hutson, A.D. and Gaile, D. P. (2009) “Clinical Trials Methodology and Biostatistics”, Principles and Practice of Gynecology Oncology, 5th Edition. Wolters Kluwer and Lippincott Williams & Wilkins, New York.

Miscellaneous

1. Hutson, A. D. (2013) University at Buffalo Biostatistics Department Celebrates 10 Years. Amstat News. August, Issue #434, page 8.

2. Hutson, A. D. (2016) Obituaries for March 2016: Richard Schmidt. Amstat News. March Theory and Methods

3. Hutson, A. D. and Vexler, A. (2017) A Cautionary Note on Beta Families of Distributions and the Aliases Within. The American Statistician. (in press; published online)

4. Shan, G. , Hutson, A., Wilding, G., Ma, C., and Tian, G. (2017) Efficient statistical inference for a parallel study with missing data by using an exact method. Statistical Methods in Medical Research (submitted)

7

5. Hutson, A. D. (2017) Quantile Planes Without Crossing via Nonlinear Programming.

Computer Methods and Programs in Biomedicine. (2nd review)

6. Hutson, A. D. and Brady, W. E. (2017) Optimizing Tests about Survival Probabilities in the One-Arm Phase II Cancer Clinical Trial Setting. Biostatistics and Biometrics 2(2): BBOAJ.MS.ID.555582.

7. Vexler, A., Zou, L. and Hutson, A. D. (2017) An Extension to Empirical Likelihood for Evaluating Probability Weighted Moments. Journal of Statistical Planning and Inference, 182 50-60.

8. Vexler, A., Yu, J., Zhao, Y., Hutson, A. D. and Gurevich, G. (2017) Expected p-values in light of an ROC curve analysis applied to optimal multiple testing procedures. Statistical Methods in Medical Research (in press)

9. Hutson, A. D. (2017) A Robust Semi-Parametric Warping Estimator of the Survivor Function With an Application to Two Group Comparisons. Statistical Methods in Medical Research (in press)

10. Yang, X., Hutson, A. D. and Wang, D. (2017) Nonparametric Estimation of Quantile and Quantile Density Function. Journal of Biometrics & Biostatistics, 8(3): 354.

11. Yu, J., Yang, L. Vexler, A. and Hutson, A. D. (2016) Easy and accurate variance

estimation of the nonparametric estimator of the partial area under the ROC curve and its application. Statistics in Medicine, 35 2251-2282.

12. Wang, D. and Hutson, A. D. (2016) A Weighted Harrell-Davis Distance Test with Applications to Censored Data. Communications in Statistics – Theory and Methods, 46 5022-5034.

13. Yu, J., Yang, L., Vexler, A. and Hutson, A. D. (2016) A generalized empirical likelihood

approach for two-group comparisons given a U-statistic constraint. Statistics, 50 435-453.

14. Yu, J., Hutson, A. D., Siddiqui, A. H. and Kedron, M. A. (2016) Group sequential control of overall toxicity incidents in clinical trials - non-Bayesian and Bayesian approaches. Statistical Methods in Medical Research, 25 64-80.

15. Hutson, A. D. (2016) Nonparametric rank based estimation of bivariate densities given censored data conditional on marginal probabilities. Journal of Statistical Distributions and Applications, 3:9.

16. Vexler, A., Chen, X. and Hutson, A. D. (2017) Dependence and independence: Structure

and inference. Statistical Methods in Medical Research (in press)

8

17. Dong, T., Attwood, K., Hutson, A., Liu, S. and Tian, L. (2017) A new diagnostic accuracy measure and cut-point selection criterion. Statistical Methods in Medical Research. (in press)

18. Zhao, Y., Vexler, A., Hutson, A. D. and Chen, X. (2016) A Statistical Software Procedure for Exact Parametric and Nonparametric Likelihood-Ratio Tests for Two-Sample Comparisons. Communications in Statistics – Theory and Methods, (in press)

19. Shan, G., Wilding, G. E., Hutson, A. D. and Gerstenberger, S. (2016) Optimal adaptive

two-stage designs for early phase II clinical trials. Statistics in Medicine, 35 1257-1266.

20. Vexler, A., Zou, L. and Hutson, A. D. (2016) Data-Driven Confidence Interval Estimation Incorporating Prior Information with an Adjustment for Skewed Data. The American Statistician, 70 243-249.

21. Hutson, A. D. (2015) A Practical and Accurate Approximation for Carrying Out Repeated Measures Power Calculations. Communications in Statistics – Case Studies and Data Analysis. 1 161-167.

22. Yu, J., Yang, L. and Hutson, A. D. (2015) What is the Proper Sample Size for Studies of

Periodontal Treatment? Dental Clinics of North America, 59 781-97.

23. Wang, D. and Hutson, A. D. (2015) Inversion Theorem Based Kernel Density Estimation for the Ordinary Least Squares Estimator of a Regression Coefficient. Communications in Statistics – Theory and Methods, 44 1571-1579.

24. Chandrasekhar, R., Shi, Y., Hutson, A. D. and Wilding, G. E. (2015) Likelihood-based

inferences about the mean area under a longitudinal curve in the presence of observations subject to limits of detection. Journal of Biopharmaceutical Statistics, 14 252-261.

25. Hutson, A. D., Wilding, G. E., Mashtare, T. L. and Vexler, A. (2015) Measures of Biomarker Dependence Using a Copula Based Multivariate Epsilon-Skew-Normal Family of Distributions. Journal of Applied Statistics, 42 2734-2753

26. Wei, L., Wang, D. and Hutson, A. D. (2015) An Investigation of Quantile Function Estimators Relative to Quantile Confidence Interval Coverage. Communications in Statistics – Theory and Methods, 44 2107-2135.

27. Chandrasekhar, R. ,Shi, Y. Hutson, A., and Wilding, G. E. (2015) A novel approach to

testing for average bioequivalence based on modeling the within-period dependence structure. Journal of Biopharmaceutical Statistics, 25 1320-1338.

28. Vexler, A., Kim, Y. M., Yu, J., Lazar, N. and Hutson, A. D. (2014) Computing Critical

Values of Exact Tests by Incorporating Monte Carlo Simulations Combined with Statistical Tables. Scandanavian Journal of Statistics, 41 1013-1030.

9

29. Dong, T., Kang, L., Hutson, A., Xiong, C. and Tian, L. (2014) Confidence interval estimation of the difference between two sensitivities to the early disease stage. Biometrical Journal, 56 270-286.

30. Vexler, A., Tao, G. and Hutson, A. D. (2014) Posterior expectation based on empirical likelihoods. Biometrika, 101 711-719.

31. Hutson, A. D., Wilding, G. E., Yu, J. and Vexler, A. (2014) Exact Inference for the Dispersion Matrix. Advances in Statistics, Volume 2014, 1-7.

32. Wilding, G. E., Wei, D. and Hutson, A.D. (2014) A Permutation-Based Approach for Combining Tests of Significance for a Common Null Hypothesis with Application to Small Sample Survival Trials. (submitted)

33. Vexler, A., Tanajian, H. and Hutson, A. D. (2014) Density-based empirical likelihood

procedures for testing symmetry of data distributions and k-sample comparisons. Stata Journal, 14 304-328.

34. Yu, J, Vexler A, Hutson A. D. and Baumann H. (2014) Empirical Likelihood Approaches

to Two-Group Comparisons of Upper Percentiles Applied to Biomedical Data. Statistics in Biopharmaceutical Research, 6 30-40.

35. Vexler, A., Tsai, W-M and Hutson, A. D. (2014) A Simple Density-Based Empirical Likelihood Ratio Test for Independence. The American Statistician, 68 158-169.

36. Wang, D. and Hutson, A. D. (2014) A Smooth Bootstrap Procedure towards Deriving

Confidence Intervals for the Relative Risk. Communications in Statistics – Theory and Methods, 43 1979-1990.

37. Wang, D. and Hutson, A. D. (2013) Smooth bootstrap-based confidence intervals for one binomial proportion and difference of two proportions. Journal of Applied Statistics, 40 614-625.

38. Hutson, A. D. (2013) Calculation of the Per Hypothesis Error Rate via Sums of Steck's

Determinants. Annals of Biometrics and Biostatistics, 1(2): 1006.

39. Vexler, A, Gurevich, G. and Hutson, A. D. (2013) An exact density-based empirical likelihood ratio test for paired data. Journal of Statistical Planning and Inference, 143 334-345.

40. Shan, G., Ma, C. X., Hutson A. D. and Wilding, G. E. (2013) Some tests for detecting trends based on the modified Baumgartner-Weis-Schindler statistics. Computational Statistics & Data Analysis, 57 246-261.

10

41. Shan, G., Ma, C. X., Hutson A. D. and Wilding, G. E. (2013) Randomized Two-Stage Phase II Clinical Trial Designs Based on Barnard’s Exact Test. Journal of Biopharmaceutical Statistics, 23 1081-1090.

42. Yu, J., Vexler, A. and Hutson, A. D. (2012) A maximum likelihood approach to

analyzing incomplete longitudinal data in mammary tumor development experiments with mice. Sri Lankan Journal of Applied Statistic, 13 61-85

43. Wang, D. and Hutson, A. D. (2013) Joint Confidence Region Estimation of L-Moment Ratios with an Extension to Right Censored Data. Journal of Applied Statistics, 40 368-379.

44. Wei, L. and Hutson, A. D. (2013) A Comment on Sample Size Calculations for Binomial Confidence Intervals. Journal of Applied Statistics, 40 311-319.

45. Hutson, A. D. and Wilding, G. E. (2012) Maintaining the exchangeability assumption for a two-group permutation test in the non-randomized setting. Applied Statistics, 39 1593-1603.

46. Shan, G, Hutson, A. D. and Wilding, G.E. (2012) Two-stage k-sample designs for the

ordered alternative problem. Pharmaceutical Statistics, 11 287-294.

47. Hutson, A. D. and Wilding, G. E. (2012) An Examination of the Relative Impact of Type I and Type II Error Rates in Phase II Drug Screening Trial Queues. Pharmaceutical Statistics, 11 157-162.

48. Shan, G., Ma, C. X., Hutson A. D. and Wilding, G. E. (2012) An efficient and exact approach for detecting trends with binary endpoints. Statistics in Medicine, 31 155-164.

49. Dong, T., Tian, L., Kang, L., Hutson, A. and Xiong, C. (2012) Parametric and non-parametric confidence intervals for the difference of sensitivities to the early disease stage between two markers. Statistics in Medicine, 30 3532-3545.

50. Wilding, G. E., Chandrasekhar, R. and Hutson, A. D. (2012) A new linear model-based approach for inferences about the mean area under the curve. Statistics in Medicine, 31 3563-3578.

51. Cai, X., Wilding, G. E., Hutson, A. D. and Java, J. (2012) Estimation and testing of the conditional correlations across continuous variable(s) for heteroscedastic data. Advances and Applications in Mathematical Sciences, 10 191-206.

52. Hutson, A., Wang, D. and Miecznikowski, J. (2012) An inversion theorem-based kernel density estimator for a weighted average and difference of weighted averages with applications. Communications in Statistics-- Theory Methods 41 1299-1312.

11

53. Wang, D., Miecznikowski, J. C. and Hutson, A. D. and (2012) Direct density estimation of L-estimates via characteristic functions with applications. Journal of Statistical Planning and Inference, 142 5567-578.

54. Wilding, G.E., Shan, G. and Hutson, A. D. (2012) Exact two-stage designs for phase II activity trials with rank-based endpoints. Contemporary Clinical Trials, 33 332-341.

55. Dong, T., Tian, L., Hutson, A. and Xiong, C. (2011) Parametric and non-parametric confidence intervals of the probability of identifying early disease stage given sensitivity to full disease and specificity with three ordinal diagnostic groups. Statistics in Medicine, 30 3532-3545.

56. Wang, D. and Hutson, A. D. (2011) A Fractional Order Statistic Towards Defining a

Smooth Quantile Function for Discrete Data. Journal of Statistical Planning and Inference, 141 3142-3150.

57. Yu, J., Vexler, A., Kim, S. and Hutson, A. D. (2011). Two-sample Empirical Likelihood Ratio Tests for Medians in Application to Biomarker Evaluations. The Canadian Journal of Statistic, 39 671-689.

58. Vexler, A., Yu, J. and Hutson, A. (2011) Likelihood testing populations modeled by

autoregressive process subject to the limit of detection in applications to longitudinal biomedical data. Journal of Applied Statistics, 38 1333-1346.

59. Vexler, A., Shan, G., Kim, S. E., Tsai, W., Tian, L. and Hutson, A. D. (2011). An

empirical likelihood ratio based goodness-of-fit test for Inverse Gaussian distributions. Journal of Statistical Planning and Inference, 141 2128-2140.

60. Wilding, G., Cai, X., Hutson, A. and Yu, Z. (2011) A linear model-based test for the heterogeneity of conditional correlations. Journal of Applied Statistics, 38 2355-2366.

61. Mashtare, T. L. and Hutson, A. D. (2011) Utilizing the flexibility of the Epsilon-skew-normal distribution for Tobit regression problems. Communications in Statistics-Theory and Methods, 40 408-423.

62. Shan, G., Vexler, A., Wilding, G. E. and Hutson A. D. (2011). Simple and Exact

Empirical Likelihood Ratio Tests for Normality Based On Moment Relations. Communications in Statistics-Simulation and Computation, 40, 141–158

63. Wang, D., Hutson, A. D. and Gaile, D. P. (2010) An exact bootstrap approach towards

modification of the Harrell-Davis quantile function estimator for censored data. Journal of Nonparametric Statistics. 22 1039-1051.

64. Wang, D., Hutson, A. D. and Miecznikowski, J. C. (2010) L-moment estimation for parametric survival models given censored data. Statistical Methodology, 7 655-667.

12

65. Miecznikowski, J. C., Wang, D. and Hutson, A. D. (2010) Bootstrap MISE Estimators to obtain bandwidth for kernel density estimation. Communications in Statistics - Simulation and Computation, 39 1455-1469.

66. Hutson, A. D. (2010) A Multi-Rater Nonparametric Test of Agreement and Corresponding Agreement Plot. Computational Statistics & Data Analysis. 54 109-119

67. Vexler, A., Liu, S., Kang, L. and Hutson, A. (2009) Modifications of the Empirical

Likelihood Interval Estimation with Improved Coverage Probabilities Communications in Statistics - Simulation and Computation, 38 2171-2183

68. Mudholkar, G. S., Asubonteng, K. O. and Hutson, A. D. (2009) Transformation for

Weibull model analysis of bathtub failure rate data in reliability analysis. Statistical Methodology 6 622-633

69. Hutson, A. D. (2009) A Concomitant Order Statistics Based Approach to Bivariate

Density Estimation. Advances and Applications in Statistical Sciences, 1 107-132.

70. Hutson, A. D. (2009) A Distribution Function Estimator for the Difference of Order Statistics from Two Independent Samples. Statistical Papers, 50 203-208.

71. Hutson, A. D., Markman, M. and Brady, M. F. (2009) A Permutation Test Approach to Phase II Historical Control Trials with an Application to the Gynecologic Oncology Cooperative Group Setting. Journal of Applied Statistics, 36 589-599.

72. Hutson, A. D. (2008) Estimating the Relative Rank Correlation: Theory and Application. Statistical Methodology, 5 46-55.

73. Hutson, A. D. (2008) A Discrete-Continuous Mixture Quantile Function Estimator with a Practical Application to Phase II Cancer Clinical Trials. Statistics in Medicine, 27 2094-2109.

74. Mudholkar, G. S., McDermott, M .P. and Hutson, A. D. (2007) Life and legacy of Samarendra Nath Roy 1906–1964. Journal of Statistical Planning and Inference, 137 3208-3212. INVITED PAPER

75. Hutson, A. D. (2007) An ``Exact'' Two-Group Median Test with an Extension to Censored Data. Journal of Nonparametric Statistics 19 103-112.

76. Gaile, D. P., Hutson, A. D., Java, J., Conroy, J. M., McQuaid, D., Rossi, M. and Nowak, N. J. (2007) Errors in Centering of Array Data can Induce Biases in Correlation Estimates. Journal of Statistical Planning and Inference, 137 3446-3461. INVITED PAPER

77. Hutson, A. D. (2006) Modifying the Exact Test for a Binomial Proportion and Comparisons with Other Approaches. Journal of Applied Statistics 33 679-690.

13

78. Hutson, A. D. (2005) Medical Diagnostic Testing Models for Multifactorial Disease

Classifications. Statistics in Medicine, 24, 2649-57.

79. Hutson, A.D. (2004) Utilizing the Flexibility of the Epsilon-Skew-Normal Distribution for Common Regression Problems. Journal of Applied Statistical Science, 31 673-683.

80. Hutson, A. D. and Reid, M. A. (2004) The Utility of Partial Cross-Over Designs in Early Phase II Randomized Prevention Trials. Controlled Clinical Trials, 25 493-501.

81. Qureshi, A. I., Hutson, A., Harbaugh, R. E., Stieg, P. E., Hopkins, L. N. (2004) Methodologies and Design Considerations in Clinical Trials Evaluating Surgery or Endovascular Treatment in Cerebrovascular Diseases. Neurosurgery, 54 248-267.

82. Hutson , A. D. (2004) A General Alternative Approach to Tobit Analysis for Modelling Markers of Disease. Journal of Applied Sciences, 4 1-4.

83. Hutson, A. D. (2004) A Semiparametric bootstrap approach to correlated data analysis problems. Computer Methods and Programs in Biomedicine, 73 129-134.

84. Hutson, A. D. (2004) Exact Nonparametric Bootstrap Confidence Bands for the Quantile Function Given Censored Data. Communications in Statistics—Simulation and Computation, 33 729-746.

85. Hutson, A. D. (2003) Nonparametric Estimation of Quantiles and Normal Ranges Given Standard One-Way ANOVA Random Effects Assumptions. Statistics & Probability Letters, 64 415-424.

86. Ernst, M. D. and Hutson, A. D. (2003) Utilizing a Quantile Function Approach to Obtain “Exact” Bootstrap Solutions. Statistical Science, 18 231-240. INVITED PAPER

87. Hutson, A. D. (2003) A Sequential Test Procedure for Monitoring a Singular Safety and Efficacy Outcome. Tropical Journal of Pharmaceutical Research, 2 197-206.

88. Hutson, A. D. (2002) A Semiparametric Quantile Function Estimator for use in Bootstrap Estimation Procedures. Statistics and Computing, 12 331-338.

89. Hutson, A. D., Fishbein, L., O'Brien, P. and Stacpoole, P. W. (2002) Accounting for Plasma Levels Below Detection Limits in a One-Compartment Zero-Order Absorption Pharmacokinetics Model. Journal of Applied Statistics, 29 1181-1190.

90. Hutson, A. D. (2002) Quasi Medians are Robust and Relatively Efficient Estimators of a Common Mean Given Multivariate Normality. Statistics & Probability Letters, 57 403-408.

14

91. Hutson, A. D. (2002) “Exact” Bootstrap Confidence Bands for the Quantile Function via Steck's Determinant. Journal of Computational and Graphical Statistics, 11 471-482.

92. Hutson, A. D. (2002) Analytical Bootstrap Methods for Censored Data. Journal of Applied Mathematics and Decision Science, 6 129-141.

93. Hutson, A. D. (2001) Bootstrap-type Confidence Intervals for Quantiles of the Survival Distribution. Statistics and Medicine, 20 1693-1702.

94. Mudholkar, G. S., Hutson, A. D., and Marchetti, C. E. (2001) A Simple Hermitian Estimator of the Quantile Function. Journal of Nonparametric Statistics, 13 229-243.

95. Hutson, A. D. (2001) Rational Spline Estimators of the Quantile Function. Communications and Statistics--Simulation and Computation, 30 377-390.

96. Hutson, A. D. (2000) A Composite Quantile Function Estimator with Applications in Bootstrapping. Journal of Applied Statistics, 27 567-577.

97. Hutson, A. D. (2000) Estimating the Covariance of Bivariate Order Statistics with Applications. Statistics & Probability Letters, 48 195-203.

98. Hutson, A. D. and Ernst, M. D. (2000) The Exact Bootstrap Mean and Variance of an L-estimator. Journal of the Royal Statistical Society--Series B, 62 89-94.

99. Mudholkar, G. S. and Hutson, A. D. (2000) The Epsilon-Skew-Normal Distribution for Analyzing Near-Normal Data. Journal of Statistical Planning and Inference, 83 291-309.

100. Muller, S., Hutson, A., Arya, V. and Hochhaus, G. (1999) Assessment of complex peptide degradation pathways via structured multi-compartmental modeling approaches: the metabolism of Dynorphin A 1-13 and related fragments in human plasma. Journal of Pharmaceutical Science, 88 938-944.

101. Hutson, A. D. (1999) Calculating Nonparametric Confidence Intervals for Quantiles Using Fractional Order Statistics. Journal of Applied Statistics, 26 343-353.

102. Hutson, A. D. (1998) Direct Estimation of the Percentile “p-value” for the One-Sample Median Test. Journal of Applied Statistics, 25 525-533.

103. Mudholkar, G. S. and Hutson, A. D. (1998) LQ-moments: Analogs of L-moments. Journal of Statistical Planning and Inference, 71 191-208.

104. Mudholkar, G. S. and Hutson, A. D. (1998) Hermitian Quantile Curves as Statistical Plots. Communications in Statistics-Simulations and Computation, 27 783-805.

15

105. Hutson, A. D., Wilson, D. C. and Geiser, E. A. (1998) Measuring Relative Agreement: Echocardiographer Versus Computer. Journal of Agricultural, Biological, and Enviromental Statistics, 3 163-174.

106. Mudholkar, G. S. and Hutson, A. D. (1997) Improvements in the Bias and Precision of Sample Quartiles. Statistics. 30 239-257.

107. Mudholkar, G. S. and Hutson, A. D. (1997) Continuity Corrected Approximations for and “Exact” Inference with Pearson's X2. Journal of Statistical Planning and Inference, 59 61-78.

108. Mudholkar, G. S. and Hutson, A. D. (1997) Asymmetric Quasimedians: Remarks on an Anomaly. Statistics and Probability Letters, 32 261-268.

109. Mudholkar, G. S. and Hutson, A. D. (1997) Some Refinements of the Quasi-Quantiles. Statistics and Probability Letters, 32 67-74.

110. Mudholkar, G. S., Freimer, M., and Hutson, A. D. (1997) On the Efficiencies of Some Common Quick Estimators. Communications in Statistics-Theory and Methods, 26 1623-1647.

111. Mudholkar, G. S. and Hutson, A. D. (1996) A Study of the Exponentiated Weibull Family of Distributions. Communications in Statistics-Theory and Methods, 25 3059-3083.

112. Phelps, C. E. and Hutson, A. D. (1995) Estimating Diagnostic Test Accuracy Using a “Fuzzy Gold Standard”. Medical Decision Making, 14 44-57.

Collaborative

1. Wentink, M. Q., Verheul, H. M. W., Pal, S. K., George, S., Voortman, J., Danchaivijitr, P.,

Adelaiye, R., Poslinski, D., Groman, A., Hutson, A. and Pili, R. (2017) Phase I Study of Dalteparin in Combination With Sunitinib in Patients With Metastatic Clear Cell Renal Carcinoma. Clinical Genitourinary Cancer. (in press)

2. Fountzilas, C., Chhatrala, R., Khushalani, N., Tan, W., LeVea, C., Hutson, A., Tucker, C., Ma, W.W., Warren, G., Boland, P. and Iyer, R. (2017) A phase II trial of erlotinib monotherapy in advanced pancreatic cancer as a first- or second-line agent. Cancer Chemotherapy Pharmacology. 80 497-505.

3. Hussein, A.A., Hinata, N., Dibaj, S., May, P. R., Kozlowski, J. D., Abol-Enein, H., Abaza, R., Eun, D., Khan, M.S., Mohler, J.L., Agarwal, P., Pohar, K., Sarle, R., Boris, R., Mane, S.S., Hutson, A., Guru, K.A. (2017) Development, validation and clinical application of Pelvic Lymphadenectomy Assessment and Completion Evaluation: intraoperative assessment

16

of lymph node dissection after robot-assisted radical cystectomy for bladder cancer. BJU International. 119 879-884.

4. Antoch, M.P., Wrobel, M., Kuropatwinski, K.K., Gitlin, I., Leonova, K.I., Toshkov, I., Gleiberman, A.S., Hutson, A.D., Chernova, O.B. and Gudkov, A.V. (2017) Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice. Aging, 9 615-626.

5. Toshkov, I.A., Gleiberman, A.S., Mett, V.L., Hutson, A.D., Singh, A.K., Gudkov, A.V. and Burdelya, L.G. (2017) Mitigation of Radiation-Induced Epithelial Damage by the TLR5 Agonist Entolimod in a Mouse Model of Fractionated Head and Neck Irradiation. Radiation Research, 187 570-580

6. Oakley, E., Hutson, A., Bellnier, D. A., Wrazen,B., Arshad, H. and Shafirstein, G. (2017) Surface Markers for Guiding Cylindrical Diffuser Fiber Insertion in Interstitial Photodynamic Therapy of Head and Neck Cancer. Lasers in Surgery and Medicine, 6 599-608.

7. Fenstermaker, R.A., Ciesielski, M.J., Qiu, J., Yang, N., Frank, C.L., Lee, K.P., Mechtler,

L.R., Belal, A., Ahluwalia, M.S. and Hutson, A.D.(2016) Clinical study of a survivin long peptide vaccine (SurVaxM) in patients with recurrent malignant glioma. Cancer Immunology Immunotherapy, 65(11) 1339-1352.

8. Warren, G.W., Dibaj, S., Hutson, A., Cummings, K. M., Dresler, C. and Marshall, J.R.

(2015) Identifying Targeted Strategies to Improve Smoking Cessation Support for Cancer Patients. Journal of Thoracic Oncology, 10 1532-1537

9. Anwar, S., Tan, W., Yu, J., Hutson, A., Javle, M. and Iyer, R. (2014) Quality-of-life (QoL) as a predictive biomarker in patients with advanced pancreatic cancer (APC) receiving chemotherapy: results from a prospective multicenter phase 2 trial. Journal of Gastrointestinal Oncology, 5 433-439.

10. Fallavollita, J. A., Heavey, B. M., Luisi, A. J. Jr., Michalek, S. M., Baldwa, S., Mashtare, T.

L., Jr., Hutson, A. D., Dekemp, R. A., Haka, M. S., Sajjad, M., Cimato, T. R., Curtis, A. B, Cain, M. E., Canty, J. M., Jr. (2014). Regional Myocardial Sympathetic Denervation Predicts the Risk of Sudden Cardiac Arrest in Ischemic Cardiomyopathy. Journal of the American College of Cardiology. 63 141-149.

11. Bharthuar, A., Khorana, A. A., Hutson, A., Wang, J. G., Key, N. S., Mackman, N, and Iyer

R. V. (2013) Circulating microparticle tissue factor, thromboembolism and survival in pancreaticobiliary cancers. Thrombosis Research 132 180-184.

12. Warren, G. W., Marshall, J. R., Cummings, K. M., Toll, B., Gritz, E. R., Hutson, A., Dibaj,

S., Herbst, R. Mulshine, J. L., Hanna, N. and Dresler, C. (2013) Addressing Tobacco Use in Patients With Cancer: A Survey of American Society of Clinical Oncology Members. Journal of Practice Oncology 9 258-262.

17

13. Warren, G. W., Marshall, J. R., Cummings, K. M., Toll, B., Gritz, E. R., Hutson, A., Dibaj, S., Herbst, R. and Dresler, C. (2013) Practice Patterns and Perceptions of Thoracic Oncology Providers on Tobacco Use and Cessation in Cancer Patients. Journal of Thoracic Oncology, 8 543-548.

14. Brasky, T. M., Li,Y., Jaworowicz Jr., D. J., Potischman, N., Ambrosone, C. B. Hutson, A. D., Nie, J., Shields, P. G., Trevisan, M., Rudra, C. B., Edge, S. B. and Freudenheim, J. L. (2013) Pregnancy-related Characteristics and Breast Cancer Risk. Cancer Causes & Control 24 1675-85

15. Morales, N. A., Romano, M. A., Cummings, M. K., Marshall, J. R., Hyland, A. J., Hutson, A.

and Warren, G. W. (2013) Accuracy of self-reported tobacco use in newly diagnosed cancer patients. Cancer Causes & Control, 24 1223-1230

16. Nwogu, C.E., Yendamuri, S., Tan, W., Kannisto, E., Bogner, P., Morrison, C., Cheney, R., Dexter, E., Picone, A., Hennon, M., Hutson, A., Reid, M., Adjei, A. and Demmy, T.L. (2013) Lung cancer lymph node micrometastasis detection using real-time polymerase chain reaction: Correlation with vascular endothelial growth factor expression. The Journal of Thoracic and Cardiovascular Surgery, 145 702-708.

17. Quan, L., Dittmar, A., Zhou, Y., Hutson, A., Stassen, A. P. and Demant, P. (2012) Susceptibility loci affecting ERBB2/neu-induced mammary tumorigenesis in mice. Genes Chromosomes Cancer, 104 631-643

18. Kasturirangan, V., Mayi, B.M., Kariapper, M.T., Lesniak, W. G., Bizimungu, R., Kanter, P., Toth, K., Buitrago, S., Rustum, Y., Hutson, A., Balogh, L. P. and Khan, M.K. (2012) In vivo Toxicity Evaluation of Gold-Dendrimer Composite Nanodevices with Different Surface Charges. Nanotechnology, 7 441-451.

19. Jaworowicz, D. J., Jr., Nie, J., Bonner, M. R., Han, D., Vito, D.,Hutson, A., Potischman, N., Trevisan, M., Muti,P., and Freudenheim, J. L. (2011) Agreement between self-reported birth weight and birth certificate weights. Journal of Developmental Origins of Health and Disease, 1 106-113.

20. Alvares, S.A.., Darcy, K. M., Hutson, A., Huang, Z. Q., Lee, P.S., Jewell, E.L., Havrilesky, L. J., Markman, M., Muggia, F. and Murphy, S. K. (2011) The regulation of MASPIN expression in epithelial ovarian cancer: Association with p53 stats, and MASPIN promoter methylation: A Gynecologic Oncology Group study. Gynecologic Oncology 123 314-319.

21. Quan, L., Stassen, A.P.M., Ruivenkamp, C.A.L., van Wezel, T., Fijneman, R.J.A., Hutson, A., Kakarlapudi, N., Hart, A.A.M. and Demant, P. (2011) Most Lung and Colon Cancer Susceptibility Genes Are Pair-Wise Linked in Mice, Humans and Rats. PLOS One, 6 e14727.

22. Pauly, J. L., Smith, L. A., Rickert, M. H., Hutson, A. and Paszkiewicz, G. M. (2010) Is lung inflammation associated with microbes and microbial toxins in cigarette tobacco smoke? Immunologic Research, 46 127-136.

18

23. Tao MH, Marian C, Shields PG, Nie J, McCann SE, Millen A, Ambrosone C, Hutson A,

Edge SB, Krishnan SS, Xie B, Winston J, Vito D, Russell M, Nochajski TH, Trevisan M, Freudenheim JL. (2011) Alcohol consumption in relation to aberrant DNA methylation in breast tumors. Alcohol 45 689-699.

24. McCormack, R. and Hutson, A. (2010) In Reply to Commentary: "What Are the Unintended Consequences of Changing the Diagnostic Paradigm for Subarachnoid Hemorrhage After Brain Computed Tomography to Computed Topographic Angiography in Place of Lumbar Puncture?" Academic Emergency Medicine 17 996-997.

25. Quan, L., Hutson, A. and Demant, P. (2010) A locus on chromosome 8 controlling tumor regionality-a new type of tumor diversity in the mouse lung. Int J Cancer, 126 2603-2613.

26. Michalek, A.M., Hutson, A. D., Wicher, C. P. and Trump, D. L. (2010) The Costs of Research Misconduct - Underappreciated Consequences: A Case Study. PLOS Medicine, 7, e1000318.

27. McCormack, R. and Hutson, A. (2010) Can Computed Tomography Angiography of the Brain Replace Lumbar Puncture in the Evaluation of Acute Onset Headache after a Negative Non-Contrast Cranial Coputed Tomography Scan? Academic Emergency Medicine 17 444-451.

28. Smith, L. A., Paszkiewicz, G. M., Hutson, A. D. and Pauly, J. L. (2010) Inflammatory response of lung macrophages and epithelial cells to tobacco smoke: a literature review of ex vivo investigations. Immunologic Research, 46 127-136.

29. Nair, B., Kariapper, M., Lesniak, W., Tan, W., Hutson, A., Khan, M., Balogh, L. P. (2009)

Toxicity Evaluation of Gold-Dendrimer Composite Nanodevices In Vitro - Difference Found Between Tumour and Proliferating Endothelial Cells. Nanotoxicology, 3 139-151.

30. Gibbs, J. F., Schlieman, M., Saxena, R., Martinick, M., Corasanti, J., Hutson, A. and Singh,

P. (2009) A Pilot Study of Urokinase Type Plasminogen Activator (uPA) Overexpression in the Brush Cytology of Patients with Malignant Pancreatic or Biliary Strictures. HPB Surgery Epub 2009 Nov 30

31. Raghavendran, K., Davidson, B. A., Hutson, A. D., Helsinki, J. D., Nodzo, S. R., Notter, R. H. and Knight, P. R. (2009) Predictive Modeling and Inflammatory Biomarkers in Rats With Lung Contusion and Gastric Aspiration. Journal of Trauma-Injury Infection and Critical Care, 67, 1182-1190.

32. Kurey I, Kobets T, Havelková H, Slapničková M, Quan L, Trtková K, Grekov I, Svobodová M, Stassen AP, Hutson A, Demant P and Lipoldová M (2009) Distinct genetic control of parasite elimination, dissemination, and disease after Leishmania major infection. Immunogenetics, 61 619-633.

19

33. Raghavendran, K., Davidson, B.A., Huebschmann, J.C., Helinski, J.D., Hutson, A.D., Dayton, M.T., Notter, R.H. and Knight, P.R. (2009) Superimposed Gastric Aspiration Increases the Severity of Inflammation and Permeability Injury in a Rat Model of Lung Contusion. The Journal of Surgical Research, 155(2), 273-82

34. Markman, M., Brady, M., Hutson, A. and Berek, J.S. (2009) Survival After Second-Line Intraperitoneal Therapy for the Treatment of Epithelial Ovarian Cancer: The Gynecologic Oncology Group Experience. Int J Gynecol Cancer, 19(2), 223-229.

35. Jayaprakash, V., Sullivan, M., Merzianu, M., Rigual, N. R., Loree, T. R., Popat, S. R., Moysich, K. B., Ramananda, S., Johnson, T., Mang, T. S., Wilson, B. C., Gill, S. R., Marshall, J. R., Hutson, A. D., Frustino, J. and Reid, M. E. (2009) Autofluorescence Guided Surveillance for Oral Cancer. Cancer Prevention Research, 11 966-974.

36. Jewell, E. L., Darcy, K. M., Hutson, A., Lee, P. S., Havrilesky L.J., Grace, L.A., Berchuck, A., Alvarez-Secord, A. (2009) Association Between the N-Terminally Truncated (ΔN) p63α (ΔNp63α) Isoform and Debulking Status, VEGF Expression and Progression-Free Survival in Previously-Untreated, Advanced Stage Epithelial Ovarian Cancer: A Gynecologic Oncology Group Study. Gynecol Oncol., 115 424-429.

37. Rubatt, J.M., Darcy, K.M., Hutson, A, Bean, S.M., Havrilesky, L.J., Grace, L.A., Berchuck, A. and Secord, A.A. (2009) Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status, and angiogenic marker expression: A Gynecologic Oncology Group study. Gynecology Oncology, 112(3), 469-74.

38. Paszkiewicz, G. M., Timm, E. A., Mahoney, M. C., Wallace, P. K., Sullivan Nasca, M. A.,

Tammela, T. L., Hutson, A. and Pauly, J. L. (2008) Increased human buccal cell autoflourescence is a candidate biomarker of tobacco smoking. Cancer Epidemiology, Biomarkers and Prevention, 17, 239-244

39. Bharali DJ, Pradhan V, Elkin G, Qi W, Hutson A, Mousa SA, Thanavala Y. (2008) Novel

nanoparticles for the delivery of recombinant hepatitis B vaccine. Nanomedicine, 4, 311-7

40. Quick, S. K., Shields, P. G., Nie, J., Platek, M. E., McCann, S. E., Hutson, A. D., Trevisan,M., Vito, D., Modali, R., Lehman, T. A., Seddon, M., Edge, S. B., Marian, C., Muti, P. and Freudenheim, J. L. (2008) Effect modification by catalase genotype suggests a role for oxidative stress in the relationship between hormone replacement therapy (HRT) use and breast cancer risk Cancer Epidemiology, Biomarkers and Prevention, 17, 1082-1087.

41. Ng PY, Donley M, Hausmann E, Hutson AD, Rossomando EF, Scannapieco FA (2007)

Candidate salivary biomarkers associated with alveolar bone loss: cross-sectional and in vitro studies. Immunol Med Microbiol 49 252-60.

42. Guru KA, Seereiter PJ, Sfakianos JP, Hutson AD, Mohler JL. (2007) Is a cystogram

necessary after robot-assisted radical prostatectomy? Urol Oncol. 25 465-467

20

43. Wei LH, Baumann H, Tracy E, Wang Y, Hutson A, Rose-John S, Henderson BW (2007)

Interleukin-6 trans signalling enhances photodynamic therapy by modulating cell cycling. British Journal of Cancer 97 1513-1522

44. Balogh, L., Nigavekar, S. S., Nair, B. M., Lesniak, W., Zhang, C., Sung. L. Y., Kariapper, M.

S., El-Jawahri, A., Llanes, M., Bolton, B., Mamou, F., Tan, W., Hutson, A., Minc. L. and Khan, M. K. (2007) Significant effect of size on the in vivo biodistribution of gold composite nanodevices in mouse tumor models. Nanomedicine. 3 281-296.

45. Secord AA, Darcy KM, Hutson A, Lee PS, Havrilesky LJ, Grace LA, Berchuck A. (2007)

Co-expression of angiogenic markers and associations with prognosis in advanced epithelial ovarian cancer: A Gynecologic Oncology Group study. Gynecol Oncol. 106 221-232.

46. Weiss JR, Baer MR, Ambrosone CB, Blanco JG, Hutson A, Ford LA, Moysich KB (2007)

Concordance of pharmacogenetic polymorphisms in tumor and germ line DNA in adult patients with acute myeloid leukemia. Cancer Epidemiol Biomarkers Prev 161038-1041.

47. Lesniak WG, Kariapper MS, Nair BM, Tan W, Hutson A, Balogh LP, Khan MK (2007)

Synthesis and Characterization of PAMAM Dendrimer-Based Multifunctional Nanodevices for Targeting alpha(v)beta(3) Integrins. Bioconjug Chem 18(4):1148-54.

48. Sola-Visner, M. C., Christenson, R. C., Hutson, A. D. and Rimsza, L. D. (2007)

Megakaryocyte Size and Concentration in the Bone Marrow of Thrombocytopenic and Nonthrombocytopenic Neonates. Pediatric Research 61 479-484.

49. Scannapieco FA, Ng P, Hovey K, Hausmann E, Hutson A, Wactawski-Wende J (2007)

Salivary biomarkers associated with alveolar bone loss. Ann N Y Acad Sci 1098:496-7 50. Fakih MG, Trump DL, Muindi JR, Black JD, Bernardi RJ, Creaven PJ, Schwartz J, Brattain

MG, Hutson A, French R, Johnson CS (2007) A phase I pharmacokinetic and pharmacodynamic study of intravenous calcitriol in combination with oral gefitinib in patients with advanced solid tumors. Clin Cancer Res. 13 1216-23

51. Segal, B. H., Davidson, B. A., Hutson, A. D., Russo, T. A., Holm, B. A., Mullan, B. A.,

Habitzruther, M., Holland, S. M. and Knight, P. R. (2007) Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice. Am J Physiol Lung Cell Mol Physiol 292 760-8.

52. Stewart, S. H., Hutson, A. and Connors, G. J. (2006) Ethnicity and Gamma-Glutamyltransferase in Men and Women with Alcohol Use Disorders. Alcohol and Alcoholism 42 24-27

53. Stewart, S. H., Hutson, A., Connors, G. J. (2006) Exploration of the Relationship between

Drinking Intensity and Quality of Life. American Journal on Addictions 15(5) 356-61.

21

54. Stacpoole, P. W., Kerr, D. S., Barnes, C., Bunch, S. T., Carney, P. R., Fennell, E. M., Felitsym, N. M., Gilmore, R. L., Greer, M., Henderson, G. N., Hutson, A. D., Neiberger, R. E., O’Brien, R. G., Perkins, L. A, Quisling, R. G., Shroads, A. L., Shuster, J. J., Silverstein, J. S., Theriaque, D. W. and Valenstein, E. (2006) Controlled clinical trial of dichloroacetate for treatment of congenital lactic acidosis in children. Pediatrics, 117 1519-31

55. Fallavollita, J. A., Luisi, A., J., Michalek, S., Valverde, A. M.,deKemp, R., A., Haka, M. S.,

Hutson, A., and Canty, J., M. (2006) Prediction of ARrhythmic Events with Positron Emission Tomography: PAREPET Study Design and Methods. Contemporary Clinical Trials. 27 374-388.

56. Hutson, A. D., Davidson B. A., Raghavendran, K., Chess, P. R., Tait, A. R., Holm, B. A.,

Notter, R. H., and Knight, P. R. (2006) Statistical Prediction of the Type of Gastric Aspiration Lung Injury Based on Early Cytokine/Chemokine Profiles. Anesthesiology, 10 73-79

57. Raghavendran, K., Davidson, B. A. , Mullan, B. A., Hutson, A. D., Russo, T.A.,

Manderscheid, P. A., Woytash, J. A., Holm, B. A., Notter, R. H. and Knight, P. R. (2005) Acid and Particulate-induced Aspiration Lung Injury In Mice: Importance of MCP-1 (Macrophage Chemoattractant Protein-1). Am J Physiol Lung Cell Mol Physiol, 289 134-143.

58. Willer, B., Kroetsch, B., Darling, S., Hutson, A. and Leddy, J. (2005) Injury rates in House

League, Select and Youth Ice Hockey. Med Sci Sports Exerc., 10 1658-1663 59. Davidson, B. A., Knight, P. R., Wang, Z., Chess, P. R., Holm, B. A., Russo, T. A., Hutson,

A., and Notter, R. H. (2005) Surfactant Alterations in Acute Inflammatory Lung Injury from Aspiration of Acid and Gastric Particulates. Am J Physiol Lung Cell Mol Physiol. 288 699-708

60. Dolan, M. G., Graves, P., Nakazawa, C., Delano, T., Hutson, A. and Mendel, F. C. (2005)

Ibuprofen and High-Voltage Electrical Stimulation Curbs Acute Edema Formation After Blunt Trauma to Limbs of Rats. Journal of Athletic Training, 40 111-115. (Kenneth L. Knight Award for Outstanding Research Manuscript)

61. Saxonhouse, M. A., Sola, M. C., Pastos, K. M., Ignatz, M. E., Hutson, A. D., Christenson, R.

D. and Rimsza, L. M. (2004) Reticulated platelet percentages in term and preterm neonates. Journal of Pediatric Hematology Oncology, 26 797-802.

62. Knight, P. R., Davidson, B. A., Nader, N. D., Helinski, J., Marschke, C., Russo, T. A.,

Hutson, A. D., Notter, R. H. and Holm, B. A. (2004) Progressive, Severe Lung Injury Secondary to the Interaction of Insults following Gastric Aspiration. Experimental Lung Research, 30 535-557.

63. Odunsi, K., Wollman, R., Ambrosone, C., Hutson, A., McCann, S., Tammela, J., Gesler, J.

P., Miller, G., Sellers, T., Cliby, W., Qian, F., Keitz, B., Intengan, M., Lele, S. and Alderfer,

22

J. (2004) Detection of epithelial ovarian cancer using H-NMR-based metabonomics. International Journal of Cancer, 113, 782-788.

64. Saxonhouse, M. A., Christenson, R. D., Walker, D. M., Hutson, A. D. and Sola, M. C. (2004)

The Concentration of Circulating Megakaryocyte Progenitors in Preterm Neonates as a Function of Post-Conceptional Age. Early Human Development 78 119-124.

65. Willer, B., Dumas, J., Hutson, A. and Leddy, J. (2004) A Population Based Investigation of

Head Injuries and Symptoms of concussion of Children and Adolescents in Schools. Injury Prevention. 10 144-148.

66. Planche, T., Agbenyega, T., Bedu-Addo, G., Ansong, D., Owusu-Ofori, A., Micah, F.,

Anakwa, C., Asfo-Agyei, E., Hutson, A., Stacpoole, P., and Krishna, S. (2003) A Prospective Comparison of Malaria with Other Severe Diseases in African Children: Prognosis and Optimization of Management. Clinical Infectious Diseases 37 890-897.

67. Stacpoole, P. W., Nagaraja, N. V. and Hutson, A. D. (2003) Efficacy of Dicholoracetate as a

Lactate-Lower Drug. A Meta Analysis. Journal of Clinical Pharmacology 43 683-691. 68. Litherland, S. A., She, J. X., Schatz, D., Fuller, K., Hutson, A. D., Peng, R. H., Li, Y.,

Grebe, K. M., Whittaker, D. S., Bahjat, K., Hopkins, D., Fang, Q., Spies, P. D., North, K. Wasserfall, C., Cook, R., Dennis, M. A., Crockett, S., Sleasman, J., Kocher, J., Muir, A., Silverstein, J., Atkinson, M., and Clare-Salzler, M. J. (2003) Abherrant monocyte prostaglandin synthase 2 (PGS2) expression in type 1 diabetes before and after disease onset. Pediatric Diabetes 4 10-18.

69. Agbenyega, T., Planche, T., Bedo-Addo, G., Ansong, D., Owusu-Ofori, A., Bhattaram, V.

A., Nagaraja, N. V., Shroads, A. L., Henderson, G. H., Hutson, A. D., Derendorf, H., Krishna, S., and Stacpoole, P. W. (2002) Population Kinetics, Efficacy and Safety of Dichloroacetate for Lactic Acidosis Due to Severe Malaria in Children. Journal of Clinical Pharmacology 43 386-396.

70. Saxonhouse, M. A., Rimsza, L. M., Stegner, J., Hutson, A. D., Christenson, R. D., and Sola,

M. C. (2003) Effects of Anoxia on Megakaryocyte Progenitors Derived from Cord Blood CD34+ Cells. European Journal of Haematology, 71 359-365.

71. Duncan, G. E., Perri, M. G., Theriaque, D. W., Hutson, A. D., Eckel, R. H., and Stacpoole,

P. W. (2003) Exercise Training, Without Weight Loss, Increases Insulin Sensitivity and Post-Heparin Plasma Lipase Activity in Previously Sedentary Adults. Diabetes Care 26 557-562.

72. Robles, L. D., Frost, A. R., Davila, M., Hutson, A. D., Grizzle, W. E., and Chakrabarti, R.

(2002) Down regulation of Cdc6, a cell cycle regulatory gene, in prostate cancer. Journal of Biological Chemistry 277 25431-25438.

23

73. Duncan, G. E., Hutson, A. D. and Stacpoole, P.W. (2002) QUICKI Is Not a Useful and Accurate Index of Insulin Sensitivity Following Exercise Training. Journal of Clinical Endocrinology & Metabolism 87 950-951.

74. Bailey, L. B., Duhaney, R., Maneval, D., Kauwell, G., Quinlivan, E., Cuadras, A., Hutson,

A., and Gregory, J. F. (2002) Vitamin B12 Status is Inversely Associated with Plasma Homocysteine in Young Women and/or A1298C Methylene Tetrahyrdofolate Reductase Polymorphisms. Journal of Nutrition 132 1872-1878.

75. Neiberger, R. E., George, J. C., Perkins, L., Theriaque, D. W., Hutson, A. D., Stacpoole, P.

W. (2002) Renal Manifestations of Congenital Lactic Acidosis. American Journal of Kidney Diseases 39 12-23.

76. Garcia, M. G., Duenas, E., Sola, M. C., Hutson, A. D., and Christenson, R. D. (2002)

Epidemilogic and Outcome Studies in Patients who Received Platelet Transfusions in the Neonatal Intensive Care Unit. Journal of Perinatology 21 415-420.

77. Garcia, M. G., Hutson, A. D. and Christensen, R. D. (2002) Effect of recombinant

erythropoietin on “late” transfusions in the neonatal intensive care unit: A meta-analysis. Journal of Perinatology 22 108-111.

78. Sullivan, S. E., Staba, S. L., Gersting, J. A., Hutson, A. D., Theriaque, D., Christensen, R. D.

and Calhoun, D. A. (2002) Circulating Concentrations of Chemokines in Cord Blood, Neonates, and Adults. Pediatric Research 51 653-657.

79. Sherman, J., Patel, P., Hutson, A., Chesrown, S., and Hendeles, L. (2001) Adherence to Oral

Montelukast and Inhaled Fluticasone in Children with Asthma. Pharmacotherapy 21 1464-1467.

80. Satoh, M., Behney, K. M., Mizutani, A., Richards, H. B., Hutson, A. and Reeves, W. H.

(2001) Titration Emulation: A Computer-Assisted Technique that Simplifies the quantification of Anti-dsDNA Antibodies Using the Crithidia luciliae Assay. Lupus 10 632-636.

81. Sola, M. C., del Vecchio, A., Edwards, T. J., Suttner, D., Hutson, A. D. and Christenson, R.

D. (2001) The relationship between hematocrit and bleeding time in very low birth weight infants during the first week of life. Journal of Perinatology 21 368-371.

82. del Vecchio, A., Sola, M. C., Theriaque, D. W., Hutson, A. D., Kao, K. J., Wright, D.,

Garcia, M. C., Pollock, B. H., Christenson, R. D. (2001) Platelet transfusions in the neonatal intensive care unit: Factors predicting patients who will require multiple transfusions. Transfusion 41 803-808.

83. Krishna, S., Nagaraja, R., Planche, T., Agbenyega, T., Bedo-Addo, G., Ansong, D., Owusa-

Oforia, A., Shroads, A. L., Henderson, G., Hutson, A., Derendorf, H., Stacpoole, S. (2001)

24

Population pharmacokinetics of intramuscular quinine in children with severe malaria. Antimicrob Agents Chemother 45 1803-1809.

84. Lossie, A. C., Whitney, M. M., Amidon, D., Dong, H.J., Chen, P., Theriaque, D., Hutson, A.,

Nicholls, R. D., Zori, R. T., Williams, C. A. and Driscoll, D. J. (2001) Distinct phenotypes distinguish the molecular classes of Angelman syndrome. Journal of Medical Genetics 38 834-845.

85. Duncan, G. E., Hutson, A. D. and Stacpoole, P.W. (2001) QUICKI Does not accurately

reflect changes in insulin sensitivity with exercise training. Journal of Clinical Endocrinology & Metabolism 9 4115-4119.

86. Stacpoole, P. W., Fisher, W. R., Flotte, T., Geiser, E. A. Theriaque, D. W., and Hutson, A. D.

(2001) A Paradigm for Teaching Hypothesis-Oriented Thinking in Medical Education. The University of Florida's Clinical Investigation Program. Academic Medicine 76 287-292.

87. Sola, M. C., del Vecchio, A., Edwards, T. J., Suttner, D., Hutson, A. D. and Christensen, R.

D. (2001) The relationship between hematocrit and bleeding time in very low birth weight infants during the first week of life. Journal of Perinatology. 21 368-371.

88. Perez, E. E., Rose, S. L., Peyser, B., Lamers, S. L., Burkhardt, B., Dunn, B. M., Hutson, A.

D., Sleasman, J. W. and Goodenow, M. M. (2001) Human immunodeficiency virus type 1 protease genotype predicts immune and viral responses to combination therapy with protease inhibitors (PIs) in PI-naive patients. Journal of Infectious Diseases. 183 579-588.

89. Fishbein L., O'Brien P., Hutson A., Theriaque D., Stacpoole P., Flotte T. (2000)

Pharmacokinetics and pharmacodynamic effects of nicotine nasal spray devices on cardiovascular and pulmonary function. Journal of Investigative Medicine 48 435-440.

90. Kauwell, G. P. A., Willsky, C. E., Cerda, J. J.,Herrlinger-Garcia, K., Hutson, A. D.,

Theriaque, D. W., Boddie, A., Rampersaud, G. C., and Bailey, L. B. (2000) Methylenetetrahydrofolate Reductase Mutation (677C → T) Negatively Influences Plasma Homocysteine Response to Marginal Folate Intake in Elderly Women. Metabolism 49 1440-1443.

91. Rampersaud, G. C., Kauwell, G. P. A., Hutson, A. D., Cerda, J. J. and Bailey, L. B. (2000)

Genomic DNA methylation decreases in response to moderate folate depletion in elderly women. American Journal of Clinical Nutrition 72 998-1003.

92. Juul, S. E., Zhao, Y., Dame, B., Hutson, A. D. and Christenson, R. D. (2000) Origin and Fate

of Erythropoietin in Human Milk. Pediatric Research 48 660-667. 93. Sola, M. C., Du, Y., Hutson, A., and Christenson, R. D. (2000) Dose-response relationship of

megakaryocyte progenitors from the bone marrow of thrombocytopenic and non-thrombocytopenic neonates to recombinant thrombopoietin. British Journal of Haematology 110 449-453.

25

94. Kauwell, G. P., Lippert, B. L., Willsky, C. E., Herringer-Garcia, K., Hutson, A. D.,

Theriaque, D. W., Rampersaud, G. C., Cerda, J. J., and Bailey, L. B. (2000) Folate Status of Elderly Women following Moderate Folate Depletion Responds Only to a Higher Folate Intake. Journal of Nutrition 130 1584-1590.

95. Sherman, J., Hutson, A., Baumstein, S. and Hendeles, L. (2000) Telephoning the patient's

pharmacy to assess adherence with asthma medications by measuring refill rate for prescriptions, Journal of Pediatrics, 136 532-536.

96. Sola, M. C., Christenson, R. D., Hutson, A. D. and Tarantal, A. F. (2000) Pharmacokinetics,

Pharmacodynamics and Safety of Administering Pegylated Recombinant Megakaryocyte Growth and Development Factor to Newborn Rhesus Monkeys. Pediatric Research 47 208-214.

97. Calhoun, D. A., Lunoe, M., Du, Y., Hutson, A. D., Young, J, Veerman, M. and Christenson,

R. D. (2000) Granulocyte colony-stimulating factor (G-CSF) serum and urine concentrations in neutropenic neonates before and following the intravenous administration of recombinant G-CSF. Pediatrics 105 392-397.

98. Baggs, J. G., Schmitt, M. H., Mushlin, A. I., Mitchell P., Eldredge, D. H., Oakes, D. and

Hutson, A. D. (1999) Association Between Nurse-Physician Collaboration and Patient Outcomes in Three Intensive Care Units. Critical Care Medicine 27 1991-1998.

99. Litherland, S. A., Xie, X. T., Hutson, A. D., Wasserfall, C., Whittaker, D. S., She, J., Hofig,

A., Dennis, M. A., Fuller, K., Cook, R., Schatz, D., Moldawer, L. L., and Clare-Salzler, M. J. (1999) Abherrant Prostoglandin Synthase 2 Expression Defines an Antigen Presenting Cell Defect in Humans at Risk for Insulin Dependent Diabetes Mellitus. Journal of Clinical Investigation 104 515-523.

100. Sleasman, J. W., Nelson, R. P., Goodenow, M. M., Wilfert, D., Hutson, A., Bassler, M.,

Zuckerman, J., Pizzo, P. A. and Mueller, B. U. (1999) Immunoreconstitution after ritonavir therapy in children with human immunodeficiency virus infection involves multiple lymphocyte lineages. The Journal of Pediatrics 134 597-606.

101. Sola, M. C., Calhoun, D. Hutson, A., and Christenson, R. D. (1999) Plasma

Thrombopoietin Concentrations in Thrombocytopenic and Non-Thrombocytopenic Patients in a Neonatal Intensive Care Unit. British Journal of Haematology 104 90-92.

102. Stacpoole, P. W., Bunch, T., Neiberger, R. M., Perkins, L. A., Quisling, R., Hutson, A.

D., and Greer, M. (1999) The Importance of Cerebrospinal Fluid Lactate in the Evaluation of Congenital Lactic Acidosis. The Journal of Pediatrics 134 99-102.

103. Bonnette, R. E., Caudill, M. A., Boddie, A. M., Hutson, A. D., Kauwell, G. P. and Bailey,

L. B. (1998) Plasma homocycst(e)ine concentrations in pregnant and nonpregnant women fed a folate controlled diet. Obstetrics & Gynecology, 92(2) 167-170.

26

104. Geiser, E. A., Wilson, D. C., Wang, D. X., Conetta, D. A., Murphy, J. D. and Hutson, A.

D. (1998) Autonomous Epicardial and Endocardial Boundary Detection in Echocardiographic Short-axis Images. Journal of the American Society of Echocardiography, 11 338-348.

105. Caudill, M. A., Gregory, J. F., Hutson, A. D., and Bailey, L. B. (1998) Folate Catabolism

in Pregnant and Nonpregnant Women Consuming Controlled Folate Intakes. Journal of Nutrition, 128 204-208.

106. Katz, P. R., Karuza, J., Kolassa, J., Hutson, A. (1997) Medical practice with nursing

home residents: results from the National Physician Professional Activities Census. Journal of the American Geriatric Society, 45 911-917.

107. Baggs, J. G., Schmitt, M. H., Mushlin, A. I., Eldredge, D. H., Oakes, D. and Hutson, A.

D. (1997) Nurse-Physician Collaboration and Satisfaction with the Decision-Making Process in Three Critical Care Units. American Journal of Critical Care 6 393-399.

108. Caudill, M. A., Cruz, A. C., Hutson, A. D., Gregory, J. F., and Bailey, L. B. (1997) Folate

Status Response to Controlled Folate Intake in Pregnant Women. The Journal of Nutrition, 127 2363-2370.

109. King, V. Constine, L., Clark, D., Schwartz, R. G., Muhs, A., Henzler, M., Hutson, A.,

and Rubin, P. (1996) Symptomatic Coronary Artery Disease After Mantle Irradiation for Hodgkin's Disease. International Journal of Radiation Oncology Biology Physics, 36 881-889.

Conference Proceedings 1. Mudholkar, G. S., Hutson, A. E. and Marchetti, C. E. (2003). The Hermitian estimator of the

quantile function: Implications for the M-estimation of location, In Statistical Methods and Practice: Recent Advances (Eds., N. Balakrishnan, N. Kannan and M.R. Srinivasan), pp. 203-229, Narosa Publishing House, New Delhi, India.

2. Nwogu, C.E., Yendamuri, S., Tan, W., Kannisto, E., Bogner, P., Morrison, C., Cheney, R., Dexter, E., Picone, A., Hennon, M., Hutson, A., Reid, M., Adjei, A., Demmy, T.L. (March 2013). Lung cancer lymph node micrometastasis detection using real-time polymerase chain reaction: Correlation with vascular endothelial growth factor expression, in Journal of Thoracic and Cardiovascular Surgery, Vol 145, pp 702-708, DOI: 10.1016/j.jtcvs.2012.023.

3. Khan, M.K., Nair, B., Kasturirangan, V., Kariapper, M.S.T., Nigavekar, S.S., Toth, K.,

Rustum, Y.M., Hutson, A., Tan, W., El-Jawahri, A., Bizimungu, R., Lesniak, W., Balogh, L.P. (2009). In Vivo Toxicity Study of Gold Composite Nanodevices for use in Imaging and Radiotherapy in Nanotech Conference & Expo 2009, Vol 2, Technical Proceedings (Eds., M Laudon, B. Romanowicz), pp 58-59.

27

4. Scannapieco, F.A., Ng, P., Hovey, K., Hausmann, E., Hutson, A., Wactawski-Wende, J. (2007). Salivary biomarkers associated with alveolar bone loss in Oral-Based Diagnostics Book Series: Annals of the New York Academy of Sciences Vol 1098 (Eds., D. Malamud, R.S. Niedbala) pp 496-497 DOI: 10.1196/annals.1384.034.

5. Stewart, S.H., Hutson, A., Connors, G.J. (Sept-Oct 2006). Exploration of the relationship

between drinking intensity and quality of life in American Journal of Additions Vol 15 (5), pp 356-361, DOI: 10.1080/10550490600860122.

6. Duncan, G. E., Perri, M.G., Theriaque, D.W., Hutson, A.D., Eckel, R.H., Stacpoole, P.W.

(March 2003). Exercise training, without weight loss, increases insulin sensitivity and postheparin plasma lipase activity in previously sedentary adults in Diabetes Care, Vol 26( 3), pp 557-562, DOI: 10.2337/diacare.26.3.557.

7. Sherman, J., Patel, P., Hutson, A., Chesrown, S., Hendeles, L. (Dec 2001). Adherence to oral

montelukast and inhaled fluticasone in children with persistent asthma in Pharmacotherapy, Vol 21(12), pp 1464-1467, DOI: 10.1592/phco.21.20.1464.34485.

8. Perez, E.E., Rose. S.L., Peyser, B., Lamers, S.L., Burkhardt, B., Dunn, B.M., Hutson, A.D.,

Sleasman, J.W., Goodenow, M.M. (Feb 15, 2001). Human immunodeficiency virus type 1 protease genotype predicts immune and viral responses to combination therapy with protease inhibitors in Journal of Infectious Diseases, Vol 183(4), pp 579-588, DOI: 10.1086/318538.

9. Kauwell, G.P.A., Willsky, C.E., Cerda, J.J., Herrlinger-Garcia, K., Hutson, A.D., Theriaque,

D.W., Boddie, A., Rampersaud, G.C., Bailey, L.B. (Nov 2000). Methylenetetrahydrofoliate reducatsase mutation (677C->T) negatively influences plasma homocysteine response to marginal folate intake in elderly women in Metabolism-Clinical and Experimental Vol 49(11), pp 1440-1443, DOI: 10.1053/meta.2000.16555.

10. Kauwell, G.A., Lippert, B.L., Willsky, C.E., Herrlinger-Garcia, K., Hutson, A.D., Theriaque,

D.W., Rampersaud, G.C., Cerda, J..J., Bailey, L.B. (June 2000). Folate status of elderly women following moderate folate depletion responds only to a higher folate intake in Journal of Nutrition Vol 130(6) pp 1584-1590.

11. Caudill, M.A., Gregory, J.F., Hutson, A.D., Bailey, L.B. (Feb 1998). Folate catabolism in

pregnant and nonpregnant women with controlled folate intakes in Journal of Nutrition Vol 128(2), pp 204-208.

12. Caudill, M.A., Cruz, A.C., Gregory, J.F., Hutson A.D., Bailey, L.B. (Dec 1997). Folate

status response to controlled folate intake in pregnant women in Journal of Nutrition Vol 127(12) pp 2363-2370.

Abstracts 1. Demant, P; Thudium, KE; Sepporta, MV; Affronti, H; Meijer, G; Prendergast, L; Mathijssen,

RHJ; Burhans, WC; Ma, WW; Hutson, A; Fetterly, GJ; Dittmar, AJ Comprehensive genetic

28

definition of susceptibility to toxic side effects of irinotecan in mice JOURNAL OF CLINICAL ONCOLOGY Volume: 33 Issue: 15 Supplement: S Meeting Abstract: e13566 Published: MAY 20 2015Sorafenib (SOR) dose reduction attenuates its immunosuppressive effects and delays hepatocellular cancer (HCC) development in the woodchuck model of hepatitis B related HCC

2. Pili, Roberto; Quinn, David I.; Hammers, Hans J.; et al.Conference: Genitourinary Cancers Symposium Location: San Francisco, CA Date: JAN 07-09, 2016 Immunomodulation by HDAC inhibition: Results from a phase II study with entinostat and high-dose Interleukin 2 in renal cell carcinoma patients (CTEP#7870). JOURNAL OF CLINICAL ONCOLOGY Volume: 34 Issue: 2 Supplement: S Meeting Abstract: 500 Published: JAN 10 2016

3. Iyer, R.; Patel, P.; Buitrago, S.; et al. Conference: European Cancer Congress Location: Vienna, AUSTRIA Date: 2015 EUROPEAN JOURNAL OF CANCER Volume: 51 Supplement: 3 Pages: S471-S471 Meeting Abstract: 2402 Published: SEP 2015 Sorafenib (SOR) dose reduction attenuates its immunosuppressive effects and delays hepatocellular cancer (HCC) development in the woodchuck model of hepatitis B related HCC

4. By: Iyer, Renuka V.; Sexton, Sandra; Curtin, Leslie; et al Conference: 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR) Location: Philadelphia, PA Date: APR 18-22, 2015 Low dose sorafenib delays hepatocellular cancer (HCC) development in the woodchuck model of hepatitis B related HCC

5. Dresler, C ; Marshall, JR ; Cummings, KM ; Toll, BA ; Gritz, ER ; Hutson, A ; Dibaj, S ; Herbst, R ; Warren, GW THORACIC ONCOLOGY PROVIDERS AND ADDRESSING TOBACCO USE IN CANCER PATIENTS: A REPORT FROM AN IASLC SURVEY Volume: 8 Pages: S1296-S1296 Supplement: 2 Meeting Abstract: P3.23-004 Published: NOV 2013

6. Pokuri, VK; Syed, JR; Yang, ZY; Field, EP; Cyriac, S; Azabdaftari, G; Pili, R; Levine, EG; Trump, DL; Hutson, A; Guru, K ; George, S Predictors of complete pathological response (pT0) to neoadjuvant chemotherapy (NAC) in muscle-invasive bladder carcinoma (MIBC) JOURNAL OF CLINICAL ONCOLOGY Volume: 33 Issue: 15 Supplement: S Meeting Abstract: e15534 Published: MAY 20 2015

7. A, Hennon M, Hutson A, Reid M, Cheney R, Adjei A. Radioguided detection of lymph node metastasis in non-small cell lung cancer. Cancer Res 2013; 73(8 Suppl. 1): Abstract #4671.

8. Reddy K, Ashton E, Sexton S, Hutson A, Tennant BC, Iyer R. Validating the woodchuck model for studying antiangiogenic therapies for human hepatocellular carcinoma (HCC) : 2012 Gastrointestinal Cancers Symposium. J Clin Oncol 2012; 30(4 Suppl.): Abstract #239.

9. Reddy K, Tennant B, Sexton S, Hutson A, Ashton E, Iyer R. Variability analysis of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) of hepatocellular carcinoma (HCC). Proc Annu Meet Am Assoc Cancer Res 2012; 53: Abstract #4546.

10. Rubatt JM, Darcy K, Hutson A, Bean SM, Havrilesky LJ, Lee PS, Grace LA, Berchuck A, Secord AA. Prognostic relevance of microvessel density in previously untreated, advanced-stage epithelial ovarian cancer and associations between CD31, CD105, p53 status, and angiogenic marker expression: A Gynecologic Oncology Group study. Gynecol Oncol 2008; 108(3 Suppl. 1): 43.

11. Warren G, Marshall J, Cummings KM, Toll BA, Gritz ER, Hutson A, Dibaj S, Herbst RS, Mulshine JL, Hanna NH, Dresler C. Addressing tobacco use and cessation in cancer patients: Practices, perceptions, and barriers reported by oncology providers : 2013 ASCO Annual Meeting Abstracts. J Clin Oncol 2013; 31(15 Suppl.): Abstract #1561.

29

12. Weiss J, Baer M, Ambrosone C, Blanco, Javier, Ford L, Hutson A, Moysich K. Polymorphisms in the glutathione S-transferase genes and treatment outcomes in acute myeloid leukemia. Proc Annu Meet Am Assoc Cancer Res 2007; 48: 809.

13. Bharthuar A, Khorana AA, Mackman N, Hutson A, Patel A, Iyer R. Association of tissue factor with prothrombotic state in pancreaticobiliary cancer (PBC) : 2010 Gastrointestinal Cancers Symposium. J Clin Oncol 2010; 28(15 Suppl.): Abstract #158.

14. Kariapper M, Kasturirangan V, Tracy E, Tan W, Kariapper IA, Lesniak W, Baumann H, Slocum H, Hutson A, Balogh L, Khan M. Dendrimer nanoparticle effects on the microenvironment: Examination of cellular motility, mitosis and inflammation. Proc Annu Meet Am Assoc Cancer Res 2010; 51: 549.

15. Fallavollita, J., Heavey, B. M., Baldwa, S., Mashtare, T. L., Hutson, A. D., Munawwar, S., deKemp, R. A., Curtis, A. B., Cain, M. E. and Canty, J. M. (2012) Volume of Denervated Myocardium is a Novel Predictor of VT/VF: Prediction of Arrhythmic Events With Positron Emission Tomography (Parepet) Study. HeartRhythm 8 1578.

16. Wallace, A ; Darcy, K ; Alvarez-Secord, A ; Hutson, A ; Tritchler, D ; Kirchgraber, L ; Grace, L ; Whitaker, R ; Berchuck, A and Havrilesky, L Loss of p16 in advanced stage epithelial ovarian cancer is associated with chemoresistant disease, suboptimal debulking and poor progression-free survival: A Gynecologic Oncology Group study GYNECOLOGIC ONCOLOGY Volume: 125 Supplement: 1 Pages: S37-S37 DOI: 10.1016/j.ygyno.2011.12.084 Meeting Abstract: 83 Published: MAR 2012

17. Iyer, R Fetterly, G; Groman, A; Hutson, A; Khushalani, N; Mohile, S; Ashton, E; Litwin, A; Grande, C; Tomaszewski, G. Sunitinib and Transarterial Chemoembolization (TACE) for Advanced Hepatocellular Carcinoma (HCC)- Final Results of a Phase 2 Trial EUROPEAN JOURNAL OF CANCER Volume: 47 Supplement: 1 Pages: S447-S447 Published: SEP 2011

18. Iyer, R.; Fetterly, G.; Groman, A.; et al.Sunitinib and Transarterial Chemoembolization (TACE) for Advanced Hepatocellular Carcinoma (HCC)- Final Results of a Phase 2 Trial

19. Source: EUROPEAN JOURNAL OF CANCER Volume: 47 Supplement: 1 Pages: S447-S447 Published: SEP 2011

20. Abbas, Ali; Hutson, Alan; Khorana, Alok; et al. Vitamin D's Role in Pathogenesis of Thromboembolism. Is This an Epiphenomenon? Source: AMERICAN JOURNAL OF GASTROENTEROLOGY Volume: 106 Supplement: 2 Pages: S55-S56 Meeting Abstract: 137 Published: OCT 2011

21. Patel, AV; Khorana, AA; Bharthuar, A; Kuvshinoff, BW; Mackman, N; Hutson, A; Iyer, RV Tissue factor is associated with a prothrombotic state in pancreaticobiliary cancer (PBC) Source: ANNALS OF SURGICAL ONCOLOGY Volume: 17 Supplement: 1 Pages: S96-S96 Published: FEB 2010

22. Iyer R, Khushalani N, Tan W, et al A phase II study of erlotinib in patients (pts) with advanced pancreatic cancer (APC) who are refractory to gemcitabine (G) EJC SUPPLEMENTS Volume: 7 Issue: 2 Pages: 391-391 Published: SEP 2009

23. Fora, A, Fakih M, Scheib S, et al New CT treatment response score for predicting survival in patients with metastatic colorectal carcinoma: A pilot study. Source: JOURNAL OF CLINICAL ONCOLOGY Volume: 27 Issue: 15 Supplement: Suppl. S Meeting Abstract: e15026 Published: MAY

30

24. Khan M, Kariapper M, Kasturirangan V, Tracy E, Lesniak W, Hutson A, Baumann H, Balogh L. In vivo inflammation study of PAMAM dendrimer nanoparticles in mice. Proc Annu Meet Am Assoc Cancer Res 2009; 50: 373.

25. Rosner, D.; Meschcheryakov, A.; Bogatyrev, V.; et al. Limitation of the Gail score and mammographic density in recruiting candidate for prevention of breast cancer in high-risk women with precancerous lesions. Source: JOURNAL OF CLINICAL ONCOLOGY Volume: 26 Issue: 15 Supplement: S Meeting Abstract: 1548 Published: MAY 20 2008

26. Parkman HP, Hutson A, Katz L, et al. Relationship of body mass index (BMI) to gastric emptying of digestible and nondigestible solidsNEUROGASTROENTEROLOGY AND MOTILITY 19 (5): 430-430 33 MAY 2007

27. Parkman HP, Hutson A, Katz L, et al.Improving analysis of gastric emptying tests using patient's age, gender, and body mass index NEUROGASTROENTEROLOGY AND MOTILITY 19 (5): 430-431 34 MAY 2007

28. Sarosiek I, Parkman H, Kuo B, et al. SmartPill as a unique tool for an insight into the relationship between transit times within the upper and the lower alimentary tract in health and disease. NEUROGASTROENTEROLOGY AND MOTILITY 19 (5): 432-432 39 MAY 2007

29. Weiss JR, Baer MR, Arnbrosone CB, Blanco JG, Hutson A, Ford LA, Moysich KB High concordance between pharmacogenetic analysis of bone marrow and buccal cell samples in acute myeloid leukemia. BLOOD 108 (11): 670A-670A 2364 Part 1 NOV 16 2006

30. Seereiter PJ, Guru KA, Sfakianos J, Hutson A, Mohler JL Is a cystogram necessary after robot-assisted radical prostatectomy? JOURNAL OF ENDOUROLOGY 20: A221-A221 Suppl. 1 AUG 2006

31. Parkman HP, Hutson A, Sarosiek I, Kuo B, Chey WD, Katz L, Semler J, McCallum RW SmartPill capsule for assessment of gastric emptying - Comparison with simultaneous gastric emptying scintigraphy AMERICAN JOURNAL OF GASTROENTEROLOGY 101 (9): S99-S99 168 Suppl. S SEP 2006

32. Jaworowicz D, Nie J, Bonner M, Han D, Vito D, Hutson A, Trevisan M, Muti P, Freudenheim JL Assessment of early life exposures: Agreement between self-reported birth weight and birth certificate weight. AMERICAN JOURNAL OF EPIDEMIOLOGY 163 (11): S31-S31 Suppl. S JUN 1 2006

33. Meguerditchian A, Huang H, Pak Y, Sossey-Alaoui K, Watroba N, Hutson A, Kulkarni S, Edge SB, Geradts J, Coignet LJ CD24/FLJ 13639 expression ratio predicts worse outcome in invasive breast cancer ANNALS OF SURGICAL ONCOLOGY 14 (2): 35-35 Suppl. S FEB 2007

34. Scannapieco, FA, Ng, PBY, Hovey, K., Hausmann, E., Hutson, A. and Wactawski-Wende, J. (2006) Salivary Biomarkers Associated with Alveolar Bone Loss

35. Angeles Alvarez Secord MD, Kathleen M. Darcy PhD, Alan Hutson PhD, Paula S. Lee MD, Laura J. Havrilesky MD, Lisa Grace, Andrew Berchuck MD (2004) Co-expression and Prognostic Relevance of Angiogenic Markers in Advanced Epithelial Ovarian Cancer: A Gynecologic Oncology Group (GOG) Study.

36. Angeles Alvarez Secord, MD, Kathleen M. Darcy PhD, Alan Hutson PhD, Paula S. Lee, MD, Elizabeth L. Jewell, MD, Laura J. Havrilesky, MD, Lisa A. Grace, Susan K. Murphy, PhD, Andrew Berchuck, MD (2005) The Role of Methylation in the Regulation of Angiogenic Inhibitors in Advanced Epithelial Ovarian Cancer: A Gynecologic Oncology Group Study

31

37. Quick SK, Nie J, Ambrosone CB, Shields PG, Muti P, Smit E, Hutson AD, Trevisan M, Freudenheim JL (2005) Effect modification by catalase genotype suggests a role for oxidative stress in the relationship between hormone replacement therapy (HRT) use and breast cancer risk. American Journal of Epidemiology 161 (11): S22-S22

38. Odunsi K, Wollman R, Ambrosone C, Hutson A, McCann S, Tammela J, Geisler J, Qian F, Keitz B, Intengan M, Lele S, Alderfer J (2004) Use of 1H-NMR-based metabonomics for detecting epithelial ovarian cancer. Journal of the Society for Gynecological Investigation. 11 4.

39. Crans DC, Yang LQ, Alfano JA, Austin LT, Jin WZ, Elliott CM, Gaidamauskas E, Godzala ME, Hutson AD, Kostyniak PJ, Willsky GR (2004) Chemical and insulin-enhancing properties of chromium and vanadium compounds: Bis(2,6-dipyridinecarboxylato)chromium(III) and 2,6-dipyridinecarboxylatodioxovanadate(V). Abstracts of Papers of the American Chemical Society. 225 23.

40. Saxonhouse, M.A., Sola, M.C., Ignatz, M.E., Pastos, K.M., Hutson, A.D., Christensen, R.D. and Rimsza, L.M. (2003) Reticulated platelet percentage and mean platelet volume changes in preterm neonates. Pediatric Research 53 1661

41. Chevuru, S.C., Christensen, R.D., Rimsza, L.M., Hutson, A.D., Theriaque, D.W. and Kays, D.W. (2003) Plasma thrombopoietin (Tpo) concentrations, circulating megakaryocyte progenitors and reticulated platelet percentages in neonates on extracorporeal membrane oxygenation (ECMO). Pediatric Research 53 2661

42. Edstrom CS, McBride J, Hutson AD, Tarantal AE, Christensen RD (2002) Pharmacodynamics of low molecular weight heparin in preterm and juvenile rhesus monkeys. Pediatric Research 51 250A

43. Chevuru, S.C., Sola, M.C., Theriaque, D.W., Hutson, A.D., Leung, W.C.W., Perez. J.A., Nelson. R.M., Kays, D.W. and Christensen, R.D. (2002) Multicenter analysis of platelet transfusion usage among neonates on extracorporeal membrane oxygenation. Pediatrics 109 e89.

44. Miller, J., Morales, A., Valledares, A., Hutson, A., Rosenbloom, A., and Silverstein, J. (2002) Comparison of glargine(gn) and traditional insulin regimens in a diabetes camp setting. Pediatric Research, 51 726.

45. Sola, M. C., Christensen, R. D., Du, Y. Hutson, A. D., Rimsza, L. M. (2002) Neonates fail to increase their marrow megakaryocyte mass in response to thrombocytopenia. Pediatric Research, 51 1410.

46. Ignatz, M. E., Saxonhouse, M. A., Sola, M. C., Pastos, K. M., Hutson, A. D., Christensen, R. D., Rimsza, L. M. (2002) Reticulated platelet percentages in non-thrombocytopenic neonates of different post-conceptional ages. Pediatric Research, 51 1411.

47. Saxonhouse, M. A., Rimsza, L. M., Stegner, J. J., Hutson, A. D., Du, Y., Christensen, R. D., Sola, M. (2002) Effects of acute hypoxia on CD34+ progenitor cells from cord blood. Pediatric Research, 51 1470.

48. Garcia, M. G., Chevuru, S. C., Saxonhouse, M. A., Theriaque, D. W., Hutson, A. D., Christensen, R. D., Sola, M. C. (2002) Effect of implementing platelet transfusion guidelines in a neonatal intensive care unit. Pediatric Research, 51 1794.

49. Chevuru, S. C., Christensen, R. D., Du, Y., Hutson, A. D., Rimsza, L.M., Theriaque, D.W., Kays, D.W. and Sola, M.C. (2002) Plasma thrombopoietin (Tpo) concentrations and the effect of recombinant Tpo on circulating megakaryocyte (MK) progenitors in neonates on extracorporeal membrane oxygenation (ECMO). Pediatric Research, 51 2261.

32

50. Bailey, L.B., Duhaney, R., Kauwell G.P.A., Maneval, D., Hutson, A., Davis, S., Quinlivan, E.P., and Gregory, J.F. (2002) Plasma homocysteine association with vitamin B12 and folate status in young women with combined polymorphisms (C677T/A1298C) of the methylenetetrahydrofolate reductase (MTHFR) gene. Faseb Journal, 16 A268-A268.

51. Duncan, G. E., Hutson, A., Stacpoole, P. W. (2001) QUICKI does not predict changes in insulin sensitivity with exercise changes. Diabetes, 50, A222-A223.

52. Del Vecchio, A., Sullivan, S. E., Christensen, R. D., Schibler, K., Hutson, A. D., Chevuru, S. C., Bartoli, A. N., Gasparini, C. and Sola, M.C. (2002) Indomethacin prolongs the bleeding time in neonates significantly more than ibuprofen. Pediatric Research, 51 2718.

53. Lossie, A. C., Whitney, M., Amidon, D., Hutson, A., Theriaque, D., Zori, R.T., Nicholls, R.D., Williams, C. A., and Driscoll, D. J. (2000) Genotype/Phenotype Correlations Among the 5 Molecular Classes of Angelman Syndrome. American Journal of Human Genetics, 67 1958.

54. Patel, P., Hutson, A., Sherman, J., Chesrown, S., Hendeles, L. (2000) Do Children With Asthma take Motelukast More Consistently Than Fluticasone Proionate? American College of Clinical Pharmacy

55. Saxonhouse, M. A., Sola, M. C., Hutson, A. D., Du, Y. and Christenson, R. D. (2000) The Concentration of Circulating Megakaryocyte Progenitors is a Function of Post-Conceptional Age in Preterm Neonates, and Predicts the Concentration of Megakaryocyte Progenitors in the Bone Marrow. Pediatric Research, 47, 1981.

56. Sola, M. C., del Vecchio, A., Edwards, T. J., Suttner, D., Hutson, A. D. and Christenson, R. D. (2000) A Low Hematocrit Prolongs the Bleeding Time of Very Low Birth-Weight Infants in the First Week of Life. Pediatric Research, 47, 2557.

57. Willsky C.E., Kauwell G.P.A., Cerda J., Herrlinger-Garcia K., Hutson A., Boddie A. and Bailey L.B. (1999) Methylenetetrahydrofolate reductase (MTHFR) mutation (677C → T) negatively influences plasma homocysteine response to marginal folate intake in elderly women. FASEB Journal, A228-A228.

58. Rampersaud, G., Kauwell, G., Hutson, A., Bailey, L. (1999) Effect of Controlled Folate Intake on DNA Methylation Status in Postmenopausal Women. FASEB Journal, 13 A700-A700.

59. Kauwell G., Lippert B., Cerda J., Hutson A., Bailey L. (1999) Folate status response to controlled dietary folate intake in elderly women. FASEB Journal, 13 A890-A890.

60. Fishbein L., O'Brien P., Hutson A., Theriaque D., Stacpoole P., Flotte T. (1999) Pharmacokinetics and pharmacodynamic effects of nicotine nasal spray devices on cardiovascular and pulmonary function. FASEB Journal, 13 A809-A809.

61. Sola, M. C., Christenson, R. D., Roskos, L., Reiber, C., Hutson, A. D. and Tarantal, A. F. (1999) Pharmacokinetics, Pharmacodynamics and Safety of Administering Pegylated Recombinant Megakaryocyte Growth and Development Factor to Newborn Rhesus Monkeys. Pediatric Research, 45 153A-153A.

62. Sola, M. C., Du, Y., Hutson, A. D. and Christenson, R. D. (1999) Dose-Response Relationship of Megakaryocyte Progenitors from Bone Marrow and Peripheral Blood of Thrombocytopenic Neonate to Recombinant Thrombopoietin. Pediatric Research, 45 1558.

63. Sola, M. C., Calhoun, D. A., Hutson, A. D. and Christenson, R. D. (1999) Do Plasma Thrombopoietin Concentrations Predict the Kinetic Mechanism Responsible for Thrombocytopenia in Neonates? Pediatric Research, 45 226A-226A.

33

64. Stacpoole, P. W., Fisher, W. R., Flotte, T. R., Geiser, E. A. and Hutson, A. D. (1999) A GCRC-Based Paradigm for Teaching Hypothesis-Oriented Thinking in Medical School. Association for Patient-Oriented Research.

65. Stacpoole, P. W., Fisher, W. R., Flotte, T. R., Geiser, E. A. and Hutson, A. D. (1999) Student Research at U.S. Medical Schools. Association for Patient-Oriented Research.

66. Fishbein L., O'Brien P., Hutson A., Theriaque D., Stacpoole P., Flotte T. (1999) Pharmacokinetics and pharmacodynamic effects of nicotine nasal spray devices on cardiovascular and pulmonary function. Journal of Investigative Medicine, 47 189A-189A.

67. Litherland, S. A., Xie, T. X., Whittaker, D. S., Hutson, A. D., Schatz, D., Moldawer, L. L., and Clare-Salzer, M. J. (1998) Abherrant Monocyte Prostoglandin Synthase-2 (PGS2) Expression; A novel cellular marker for IDD risk. Diabetes, 47 834.

68. Sleasman, J. W., Nelson, R. P., Goodenow, M. M., Wilfert, D., Hutson, A., Heath-Chiozzi, M., Bassler, M., Zuckerman, J., Pizzo, P. A. and Mueller, B. U. (1997) Immunoreconstitution of CD45RA and CD45RO CD4(+) cells occurs independent of virologic response in HIV-1 infected children treated with ritonavir. Journal of Investigative Medicine 46 62-62.

69. Shepard, T. M., Almond, B., Hevia, A., Hutson, A. D., Stacpoole, P. W. and Flotte, T. (1998) Pharmacokinetics and pharmacodynamics of a nicotine nasal spray. Journal of Investigative Medicine, 46, 18A.

70. Clark, D., Rubin, P., Hutson, A., McDermott, M., Constine, L., and Nelson, D. (1993) Increased Incidence of Second Malignant Neoplasms (SMN) in Hodgkin's Disease: 30 Year Follow-up. International Journal of Radiation Oncology Biology Physics 27 233-234.

71. Cowens, J. W., Greco, W., Hutson, A., Sewernyak, K., and Kanter, P. (1990) Pharmacokinetics of Liposome Encapsulated Doxorubicin in the Mouse. Proceedings of the American Association for Cancer Research 31 381.

Software Packages 1) tsc: Likelihood-ratio Tests for Two-Sample Comparisons http://cran.r-project.org/web/packages/tsc/index.html 2) SAS CODE FOR: A Robust Semi-Parametric Warping Estimator of the Survivor Function

With an Application to Two Group Comparisons https://www.researchgate.net/publication/289540278_SAS_CODE_FOR_A_Robust_Semi-Parametric_Warping_Estimator_of_the_Survivor_Function_With_an_Application_to_Two_Group_Comparisons

Technical Reports Hutson, A. D. (2004) Bootstrap Smoothing Strategies Based on Uniform Spacings with Practical Applications. Department of Biostatistics, University at Buffalo. Hutson, A. D. (2000) A Painless Method for Standard Repeated Measures Power Calculations. Technical Report, Department of Statistics, University of Florida. Hutson, A. D., Fishbein, L., O'Brien, P. and Stacpoole, P. W. (2000) Accounting for Plasma Levels Below Detection Limits in a One-Compartment Zero-Order Absorption

34

Pharmacokinetics Model. Technical Report 2000-02, Department of Statistics, University of Florida.

Hutson, A. D. and Ernst, M. D. (1998) An Exact Method For Calculating the Bootstrap Percentiles of a Functional of Order Statistics. Technical Report 582, Department of Statistics, University of Florida. Mudholkar, G. S., Hutson, A. D., and Marchetti, C. E. (1996) A Simple Hermitian Estimator of

the Quantile Function with an application to M-Estimators of Location. Department of Statistics and Biostatistics Technical Report 96/02, Department of Biostatistics, University of Rochester.

Conference Sessions Organized Session Chair, American Statistical Association “175 Years of the American Statistical Association and Its 110 Presidents”, 2014, Boston, MA Session Chair, International Statistics Conference 2011, Colombo, Sri Lanka Conference Council Stochastic Models in Reliability Engineering, Life Sciences and Operations Management. February 2010, Beer Sheva, Israel. Chair for IMS Mini-Meeting on Imaging, Classification, and Clustering Analysis. January 2001, Gainesville, FL. Program committee for Mathematical Methods in Biomedical Imaging. August 2000, San Diego, CA. Session organizer and presenter for the International Conference On Order Statistics & Extreme Values -Theory & Applications December 18 -20, 2000 Mysore, India Invited Talks 2016 Syracuse University “A Cautionary Tale on Beta Families of Distributions and the Aliases Within” 2016 Texas Tech University Health Sciences Center School El Paso “An examination of the relative impact of type I and type II error rates in phase II drug screening trial queues” 2014 Roswell Park Cancer Institute/CRS “Overview of Clinical Trials: Statistical Design Issues” 2013 University of Pittsburgh “Measures of Biomarker Dependence Using a Copula Based Multivariate Epsilon-Skew-Normal Family of Distributions”

35

2011 International Statistics Conference (special guest lecture), Colombo, Sri Lanka, “A Practical Guide to Exact Bootstrap Methodology” 2010 SMRLO’10, Beer Sheva, Israel. “An Inversion Theorem Based Kernel Density Estimator for a Weighted Average and Difference of Weighted Averages with Applications” 2008 University of Kentucky “Order Statistics, Quantile Functions and the Bootstrap” 2008 Lung Cancer Symposium. Invited Discussant to “Special Populations” session. 2008 Roswell Park Cancer Institute/CRS “Statistical Design Issues in Clinical Trials” 2008 Roswell Park Cancer Institute/CRS subcommittee “Statistical Design Issues in Clinical Trials” 2007 Ohio State “The Tail Extrapolation Quantile Function Estimator” 2007 Gynecologic Oncology Group National Meeting. “UB/RPCI/GOG Biostatistics Relationships” 2007 Cornell University “Order Statistics, Quantile Functions and the Bootstrap” 2007 University at Buffalo. Department of Surgery retreat. “Clinical Trials: Statistical Design Issues” 2006 McMaster University “Order Statistics, Quantile Functions and the Bootstrap” 2006 University of Castilla-La Mancha, International Conference on Mathematical and

Statistical Modeling in Honor of Enrique Castillo “A Multivariate Concomitant Order Statistics Based Approach to Density Estimation”

2005 Gynecologic Oncology Group National Meeting. “What do you mean, it's not feasible?” 2005 University at Buffalo. College of Pharmacy. “A Permutation Test Approach to Phase II Historical Control Trials with an Application to the Gynecologic Oncology Cooperative Group Setting” 2003 University at Buffalo. College of Medicine. Clinical Trials Bootcamp. 2003 Buffalo-Niagara Chapter of ASA. Presented talk entitled “Bootstrap Smoothing Strategies Based on Uniform Spacings with Practical Applications.” 2003 University of New York at Buffalo. Presented talk entitled “A Sequential Test Procedure for Monitoring a Singular Safety and Efficacy Outcome” 2002 State University of New York at Buffalo. Presented talk entitled “Exact Bootstrap

36

Methods for Censored Data.” 2001 Roswell Park Cancer Institute at Buffalo, NY. Presented talk entitled “Extending Tobit Analysis for Modelling Markers of Disease.” 2001 National meeting for the Association of GCRC Biostatisticians at Atlanta. Presented talk

8/01 entitled “Co-Authorship with GCRC Clinicians: The University of Florida Experience and the Yale University Experience.”

2001 Indianapolis University Purdue University at Indianapolis. Presented talk 2/01 entitled “Order Statistics, Quantile Functions and the Bootstrap.” 2000 Cleveland Clinic Foundation. Presented talk 10/00 entitled “Order Statistics, Quantile Functions and the Bootstrap.” 2000 Upstate Medical University of New York. Presented talk 10/00 entitled “Two Interesting Collaborative Modelling Problems.” 1998 SRCOS/ASA Summer Research Conference. Presented talk 6/98 entitled “Estimation of Quantile Functions and Applications.” 1998 IISA International Conference. Presented talk 10/98 entitled “Calculating the Exact Bootstrap Mean and Variance of an L-estimator.” Scientific Review Committees Member NIH Special Emphasis Panel ZDK1 GRB-6 (O4) (2017) JDRF Biostatistical Reviewer Strategic Research Agreement (2017) Member GOG HRC (2016-) Member NRG Scientific Review Committee (2016-) Review of U.S.-Israel Binational Science Foundation – application (2017) Member PCORI Merit Review: Improving Healthcare Systems (2016) Member NIH/CTSA U24 Trial Innovation Centers (2016) Ad-hoc member NIH ZDE1 GZ (06) (2016) Member NIH-PEPR Special Emphasis Panel (2015) Member OSU-CERTS DSMB (2015-) Ad-Hoc Member NIH Panel ZDE1 JR (08) (2015) Member NIH Special Emphasis Panel ZDK1 GRB-N (M3) (2015) Member NIH Special Emphasis Panel ZDK1 GRB-J (M3) (2015) Member NIH Special Emphasis Panel GRB-J M3 (M3) (2015) Statistical Reviewer Congressionally Directed Medical Research Programs (CDMRP) Clinical and Rehabilitative Medicine Research Program (CRMRP) – Reconstructive Transplantation Research (2014) Member NIH KNOD Study Section (2005-2007, 2014) OIG report studying Data and Safety Monitoring Boards at NIH (2013) – Content area expert Member ZNS NIH Review Committee (2013)

37

Member of the Data Monitoring Committee (DMC) for CSP #573 - "A Randomized Trial of Medical and Surgical Treatments for Patients with GERD Symptoms that are Refractory to Proton Pump Inhibitors",

Member ZDE1 VH01NIDCR Clinical Trial Planning Grant Review (2012) Member of the NIH/NIAID Data Safety Monitoring Board for the Inner City Asthma Consortium (ICAC), Consortium of Food Allergy Research (COFAR) and Asthma and Allergic Disease Cooperative Research Centers (AADCRC), 2003- . Special Emphasis Panel/Scientific Review Group 2012/08 ZNS1 SRB-G Member ZDE1 RK (19) 1 NIDCR Clinical Trial Planning Grant Review (2012) Romanian National Research Council (2012) NIH PROMIS Special Emphasis Panel (2012) VA clinical trial panel review (2012) Koman Foundation Post-doctoral Fellowship review (2012) Chair ZDE1 JH NIH Study Section (2011) Member ZDE1 JH NIH Study Section (2010) Reviewer Commision Nacional De Investigacion Centifica Y Tecnologica (CONICYT) (2010) (Chile) Member NIH SEP special Study Section (2009) Reviewer Austrian Science Fund (2009) National Institute of Dental and Craniofacial Research Special Emphasis Panel (2009) Reviewer German Research Foundation (The Clinical Trials Programme) (2008, 2009) Member DSMB for NIH sponsored Oral Cleft prevention trial (2007-2010) Member DSMB for FDA sponsored CoQ10 formulation trial (2006-2012) Member Health of the Population Fellowship Review NIH Special Emphasis Panel (2006) Member NIH Special Study Section (2006, Secondary Chair) Member Gynecologic Oncology Group (GOG) Protocol Development Committee, (2006-) Member Gynecologic Oncology Group (GOG) Protocol Committee, (2004-2006) Member Gynecologic Oncology Group (GOG) Committee on Experimental Medicine, (2004-2008) Member Gynecologic Oncology Group (GOG) Tissue Utilization Subcommittee (2004- 2008) Member Gynecologic Oncology Group (GOG) Protocol 210 Subcommittee (2004-2008) Member of UF College of Nursing's Biobehavioral Research Center Pilot Core, (2001-2002) Member of UF's GCRC Advisory Committee (1996-2002) Reviewer for Lupus Research Institute, Clinical Methodologies Task Force (2002) Committees and Service American Statistical Association Committee on ASA Archives and Historical Materials (2014-) SUNY Faculty Diversity Program Review Committee (2010-2011) University at Buffalo. Chair for two Assistant Professors, search committees in Biostatistics (2002) Chair for one Professor, search committee in Biostatistics (2002) Chair for one Assistant Professor search committee in Biostatistics (2003)

38

Member on the Ad hoc Committee on Promotions to Clinical Ranks (2003) Member Academic Affairs Committee (2003-2004 ) Member Dean of Public Health and Health Professions search committee (2003) Member Chair of Social and Preventive Medicine search committee (2003) IRCAF Review Committee (2003) Undergraduate Curriculum Committee (2004- 2005) Chair for Assistant Professor Search Committee (2004) Chair for Assistant Professor Search Committee (2005) Chair for Associate Professor Search Committee (2005) Chair for Rehabilitation Science Chair Search Committee (2005-2006) Member Chair for Health Behavior Search Committee (2005-2006) MSTP Steering Committee (2005-2007) Undergraduate Education Advisory Council (2006-2007) Gifted Math Program Advisory Council (2006-) UB2020 Extreme Events Guiding Team (2006-2007) UB2020 Bioinformatics Guiding Team (2006-2007) Strategic Strengths Faculty Advisory Council (2006-2007) TaskForce to identify the infrastructure needs for the “Health and Wellness Across the Life Span” Strategic Strength (2007) Center of Excellence Executive Committee (2007-2008) Informatics Task Force (2007-2008) Member SPHHP/Law School Joint Faculty Search Committee (2007-2008) Member Assistant Professor Search Committee (2008) SPHHP Core Curriculum Committee (2008) Member Department of Pediatrics Chair Search Committee (2009) Member CTSA Steering and Planning Committee (2010-2015) Member Exercise Science and Nutrition Chair Search Committee (2012) Chair for Social and Preventive Medicine Chair Search Committee (2012) UB Instructional Facilities Committee (2012-) UB Faculty Liason Committee (2012-2013) UB Policies and Practices Committee (2012-2013) UB Faculty Senate Ad-Hoc Decanal Review Committee (2013-2014) UB/BCTRC Clinical Trials Data Management System Selection Committee (2013-2014) Clinical Research Center/Clinical Trials Office Advisory Council (2014-2015) Gen Ed working group on "quantitative reasoning" (2014) Judge: Sigma Xi graduate research competition (2014) Member Dean of Public Health and Health Professions search committee (2014-2015) Member General Education Steering Committee (2014-15) Chair Gen Ed Quantitative Reasoning Subcommitee (2015) Member Health Services Faculty Search (2015) RPCI RPCI Genomics Pilot Project Steering Committee (2013) Graduate Education Roundtable 2012-2015 CRPC Committee 2007-2016 CCSG Steering Committee 2005-2010 Alliance Foundation Scientific Review Committee 2005-

39

Data Safety Monitoring Board, 2008-2012 Scientific Review Committee, 2002- CCSG Microarray Resource Steering Committee 2005-2010 Investigational New Drug Serious Adverse Event Trending Committee 2011- Response Review Committee 2013- Research & Education IT Governance Committee Tier I 2013- Book Reviews Reviewed Warren Gilchrist's draft manuscript on quantile functions that was accepted for publication. Reviewed one draft manuscript for Springer-Verlag. Reviewed three draft manuscripts for Duxbury Press. Refereeing Journal Articles Reviewed one paper Journal of Nonparametric Statistics Reviewed one paper Stochastic Environmental Research and Risk Assessment Reviewed one paper BMC Medical Research Methodology Reviewed one paper Journal of Pediatric Biochemistry Reviewed one paper BMJ Open Reviewed three papers for PLOS One Reviewed two papers for JAMA-Oncology Reviewed one paper for Ingeniería y Ciencia Journal Reviewed one paper for Statistics and Operations Research Transactions Reviewed one paper for BMC Neuroscience Reviewed one paper for Epidemiology Reviewed one paper for Journal of Biopharmaceutical Statistics Reviewed two papers for Journal of Applied Statistics Reviewed one paper for the Journal of Hydrology Reviewed one paper for Annals of the Institute of Statistical Mathematics Reviewed one paper for Annals of Statistics Reviewed three papers for Statistics & Probability Letters Reviewed one paper for Cancer Immunology Immunotherapy Reviewed one paper for Australian and New Zealand Journal of Statistics Reviewed two papers for Statistics Reviewed one paper for Clinical Trials Reviewed one paper for Annals of Epidemiology. Reviewed five papers for Communications in Statistics Reviewed ten papers for Statistics in Medicine. Reviewed four papers for Computational Statistics and Data Analysis. Reviewed two papers for Computer Methods and Programs in Biomedicine. Reviewed one paper for Journal of Statistical Computation and Simulation. Reviewed three papers for Journal of the American Statistical Association.

40

Reviewed two papers for Journal of the Royal Statistical Society-Series B. Reviewed two papers for The Journal of Multivariate Analysis. Reviewed one paper for Lifetime Data Analysis. Reviewed one paper for JABES. Reviewed one paper for JASN. Reviewed seven papers for Journal of Statistical Planning and Inference. Reviewed one paper for Biometrics Journal. Reviewed one paper for Biostatistics,. Reviewed two papers for Biometrics. Reviewed one paper for Technometrics. Reviewed one paper for Psychometrika. Reviewed one paper for Journal of Computational and Applied Mathematics. Reviewed one paper for the Journal of Probability and Statistics Reviewed one paper for the Scandinavian Journal of Statisitcs Tenure and Promotion Reviews Letter for promotion to Clinical Associate Professor University of Pennsylvania Letter for tenure and promotion to Associate Professor, Stony Brook University Letter for promotion to Professor, University of Florida Letter for promotion to Professor, University of Texas Letter for tenure The Ohio State University Letter for promotion to Full Professor at the University of Kansas Letter for promotion to Full Staff at St. Jude’s Children’s Hospital Letter for tenure and promotion to Associate Professor at the University of Pittsburgh Evaluation of Professor, Northwest University, South Africa Letter for promotion to Research Associate Professor at the University of Pittsburgh Letter for promotion to Associate Professor, SUNY Albany Letter for promotion to Associate Professor, University of Texas Letter for promotion to Associate Professor, Georgetown University Letter for promotion to Associate Professor, Shamoon College of Engineering Two letters for suitability to be hired, The Ohio State University Letter for promotion to Professor, The Pennsylvania State University College of Medicine Letter for promotion to Professor, The University of Pittsburgh Two letters for promotion to Associate Professor one to Professor, Northwestern University Letter for promotion to Assistant Professor, Vanderbilt University Letter for promotion to Professor, University of Kentucky Teaching Activities Applied Statistics for the Social Sciences, University of Rochester (1994,1995) Introduction to Biostatistics, University of Florida (1997, 1998, 1999) Advanced Topics in Biostatistics, University of Florida (1999)

41

Research Design and Biostatistics for Physician Assistants, University of Florida (1998) Science of Clinical Research, University of Florida (1996-2001) Special Topics (bootstrap methods), University at Buffalo (2004, 2008, 2011) Regression Analysis, University at Buffalo (2004, 2008) Survival Analysis, University at Buffalo (2005, 2011, 2013) Methods of Clinical Research (team taught), University at Buffalo/RPCI (2007) Special Topics (advanced bootstrap methods), University at Buffalo (2008) Concepts in Scientific Misconduct (team taught) RPCI 2010 Grants and Contracts ACTIVE 4 R01 CA162139-05 (Barakat) 8/1/2014-7/31/2017 0.00 calendar Sloan-Kettering Institute for Cancer Research $133,403 Prospective Evaluation of Lower Extremity Lymphedema in Women Undergoing Radical Surgery for Gynecologic Cancers This subcontract will support the NRG Oncology collaboration in this study which intends to determine the incidence and impact of lower extremity lymphedema following surgical treatment of gynecologic cancer. 5 UG1 CA189867-03 (Bruner) 8/1/2014-7/31/2019 0.60 calendar NIH $10,431,984 NRG Oncology NCORP Research Base SDMC The objective of this proposal is to establish and maintain the NCORP (National Cancer Institute Community Oncology Research Program) for the NRG Oncology research base. 5 U10 CA 180822-03 (Constantino/Hutson/Dignam) 3/15/2016-2/28/2019 2.4 calendar NIH $2,004,824 NRG Oncology Statistical and Data Management Center

The integrated resources, organizational structure, disease expertise, noteworthy experience, and focused dedication of the Statistics and Data Management Center provide the infrastructure

42

essential for data collection, abstraction, quality control, analysis, and publication of NRG Oncology research. 2 P01 CA055791-22 (Gollnick) 6/16/2015-1/31/2020 1.92 calendar NIH $1,372,368 PDT Optimization and Mechanisms: Core C The overall hypothesis of this program project grant is that PDT is an effective therapy for HNSCC, which will result in long-term tumor responses that compare to the current treatment modalities, but will result in significantly fewer quality of life issues. The overall goal of the current application is to move PDT from a niche therapy to the standard of care (SoC) for HNSCC, thus providing a novel treatment option for HNSCC with lower associated morbidities than the current SoC for this malignancy. 5 P30 CA 016056-39 (Johnson/Brady) 5/1/2014-4/30/2019 1.92 calendar NIH/NCI-RPCI (Subcontract) $121,622 Cancer Center Support Grant - Biostatistics Shared Resource Roswell Park Cancer Institute’s Cancer Support Grant (CCSG) includes six programs and 14 core resources. Support is provided for leadership, development funds, planning and evaluation and administration. The Biostatistics Shared Resource ensures that CCSG investigators have ready access to expert biostatisticians support and service to carry out basic science, translational, clinical, and population-oriented research. 5 U24 CA196067-02 (Jordan) 4/22/2015-3/31/2020 0.00 calendar NIH $2,254,109 NRG Oncology Biospecimen Bank The collection, management and distribution of high quality and well annotated biospecimens associated with NRG clinical trials data will lead to translational studies for validating biomarkers of tumor prognosis and prediction of response to therapy, ultimately leading to improved treatment of cancer patients. These activities will support improved quality of biospecimens and expanded access for translational scientists, thus leading to better quality research and identifying appropriate patients for personalized approaches to improved cancer care. 5 R01 CA 158318-05 (Odunsi) 9/1/2011-7/31/2018 0.45 calendar NIH-RPCI (Subcontract) $210,237 mTOR Inhibition for Generating Memory T Cells to Enhance Ovarian Tumor Immunity

The goal of this study is to generate durable CD+8 T cell responses against epithelial ovarian cancer (EOC) for extending remission rates. 3 P50 CA 159981-04 (Odunsi) 9/1/2013-6/30/2018 1.05 calendar NIH $1,607,030 RPCI-UPCI Ovarian SPORE

43

The overall goal of the University of the Roswell Park Cancer Institute (RPCI) and University of Pittsburgh (UPCI) Ovarian Cancer SPORE is to reduce the morbidity and mortality of ovarian cancer through innovative translational research. R21 AI123558 (Russo) 3/1/2016-2/28/2018 0.12 calendar NIH $150,000 Development of a diagnostic test for hypervirulent Klebsiella pneumoniae The objective of this proposal is to identify a specific genotypic and/or phenotypic marker for hvKP. Although a hypermucoviscous phenotype, as defined by a positive string test, has been used to discriminate hvKP, this test is NOT optimally sensitive or specific, especially in regions of lower hvKP Prevalence. 1 R01 CA-196310-01A1 (Shafirstein) 12/1/2015-11/30/2020 1.20 calendar NIH $290,367 Integrated Image-Guided Dosimetry and Treatment Planning for Photodynamic Therapy We hypothesize that our integrated treatment planning and dosimetry system, with optimal light fluence rate and fluence, will improve the response to I-PDT of LAHNC. 5 U10 CA180868-03 (Wolmark) 4/14/2014-2/28/2019 0.00 calendar NIH $17,191,877 NRG Oncology Translational Research Scientist NRG Oncology's primary mission is to improve the lives of adults with cancer by conducting well-designed and well-executed multi-institutional clinical and translational research trials. 1514204 (Zhang) 8/15/2015-7/31/2018 1.00 calendar National Science Foundation $199,033 III: Medium: High-Dimensional Interaction Analysis in Bio-Data Sets This project develops multi-disciplinary approaches that integrate computer science, statistics, and epidemiology techniques to mine interaction relationships among attributes and phenotypes (traits or class labels) in biological data sets. Specifically, this project develops innovative and statistically sound methodologies for mining novel interactions within attributes or between attributes and phenotypes to help identify critical factors in biological applications. Previous Analysis for Incomplete Data in Oral Health/Ventilator-associated Pneumonia Study, NIH, Co-Inv Anti-Tumor Mechanisms and Therapeutic Effects of Vitamin D, NIH, Co-Inv GOG Oncology Statistical and Data Management Center, NIH, Co-Inv

44

Buffalo Clinical and Translational Research Center, NIH, Co-Inv Anti-Tumor Mechanisms and Therapeutic Effects of Vitamin D, NIH, Co-Inv Gynecologic Oncology Group Statistical and Data Center, NIH, statistician Analysis for Incomplete Data in Oral Health/Ventilator-associated Pneumonia Study, NIH, Co-Inv Targeting HIF-1 Alpha in Renal Cell Carcinoma: The Role of HDAC Inhibitors, NIH, Co-Inv Alan Hutson A Phase I Study of Eriotnib in Patients with Permalignant Lesions of the Lung, NIH, Co-Inv Alan Hutson Vitamin D in Prostate Cancer: Tumor Vasculature, NIH, Co-Inv Alan Hutson Cancer Center Support Grant, Biostatistics Resource, NIH, PI Alan Hutson Preliminary Product Development Review of Hepairx air Cleaning System, NYSTAR-CAT, PI Alan Hutson A Clinical Trial of Selenium and Prostate Biomarkers, NIH, Co-Inv Alan Hutson Ovarian Cancer Detection using H-NMR Based Metabonomics, NIH, Co-Inv Alan Hutson Endogenous hormones and premenopausal breast cancer risk, NIH, Co-Inv Alan Hutson Oral Health and Ventilator-Associated Pneumonia, NIH, Co-Inv Alan Hutson Salivary Biomarkers to Predict Alveolar Bone Loss, NIH, Co-Inv Alan Hutson Hibernating Myocardium and Sudden Cardiac Death, NIH, Co-Inv Alan Hutson Genetic Markers of CHD in Men and Women, NIH, Co-Inv Alan Hutson Fasting glucose in long-term breast cancer survival , NIH, Co-Inv Alan Hutson NYSTAR Faculty Development grant. PI Alan Hutson The General Clinical Research Center National Institutes of Health/National Center for Research Resources, NIH and NCRR, Co-Inv Alan Hutson. Estimation of quantile functions and applications, CLAS Research Initiation Project, University of Florida, PI Alan Hutson.

45

Velopharyngeal Function for Speech After Palatal Surgery, NIH, Biostatistician Alan Hutson Pathobiology and treatment of malaria in Africa, WHO and NIH, Co-PI Alan Hutson. HIV-1 variants within PBMC subpopulations in infants, NIH, Co-Inv Alan Hutson. Dose response to exercise and cardiovascular health, NIH, Co-Inv Alan Hutson. Folate requirements of pregnant human subjects, NIH, Co-Investigator Alan Hutson. Thrombocytopenia in patients in the neonatal intensive care unit, Co-Inv Alan Hutson. Pathogenesis and treatment of thrombocytopenias of neonates, Biostatistician Alan Hutson. Activity-dependent Plasticity after Spinal Cord Injury, Collaborator Alan Hutson. The Role of Alpha Defensins in Cystic Fibrosis Lung Disease, NIH, Consultant Alan Hutson. Mitochondrial Encephalomyopathies and Mental Retardation, NIH, Co-Inv Alan Hutson. Dichloracetate treatment of congenital lactic acidosis, FDA, Co-Inv Alan Hutson. The detection of early renal dysfunction in Type I Diabetes Mellitus (DM) by correlation of

macrophage prostaglandins (PGs) production and renal hyperfiltration (RHF), NIH, Consultant Alan Hutson.

Human kinetics and metabolism of disinfection by-products of water chlorination, EPA, (funding pending the result of another study) Statistical Consultant Alan Hutson. Folate requirements by MTHFR genotype for nonpregnant women, USDA, Biostatistician Alan Hutson. Evaluating the role of PGS2 expression in IDDM for use in risk assessment and therapeutic intervention,UF College of Medicine, Consultant Alan Hutson. Arginine & immune status in elderly with pressure ulcers, NIH, Statistician Alan Hutson. Development of mechanisms of fetal/neonatal cytopenias, NIH, Statistician Alan Hutson. Central nervous system modulation of visceral pain in Persian Gulf War Syndrome, VA, Consultant Alan Hutson. Novel urine markers of disease activity in SLE, NIH, Biostatistician Alan Hutson K Award Mentoring

46

Scott Stewart (Co-Mentor) K23 Richard Blondell (Co-Mentor) K23 Krishnan Raghavendran (Co-Mentor) K23 Chukwumere Nwogu (Collaborator) K23 Ellen Volpe KL2 Nikhil Satchidanand KL2 Kevin Eng (primary) K01 Waheed Adedeji (co-mentor) K43 SPORE Career Development Mentor Kevin Eng (Co-Mentor) Andre Bakin (Co-Mentor) UB Mentoring Pinaki Sarder (Pathology) Global Health Implementation Research Fellowship Mentor Anthony Fernando Graduate Students Committee Member, Aaron Crowley, M.A. Biostatistics (2015) Thesis Examiner, Kevin Murray, University of Sydney (2015) Chair, Xin Yang, Ph.D. Biostatistics (current) Committee Member, Li Zou, Ph.D. Biostatistics (current) Committee Member, Shiva Dibaj, Ph.D. Biostatistics (2016) Chair, Tengda Lin, MA Biostatistics (2015) Committee Member, Ge Tao, Phd Biostatistics (current) Committee Member, Xeiwi Chen, Phd Biostatistics (2016) Committee Member, Luge Yang, Phd Biostatistics (2015) Committee Member, Mark Baker, Phd Biostatistics (2015) Committee Member, Mojgan Golzy, PhD Biostatistics (2015) Committee Member, Tuochuan Dong, Phd Biostatistics (2014) Committee Member, Jingjing Yin, Phd Biostatistics (2014) Committee Member, Joe Consiglio Ph.D. Biostatistics (2014) Committee Member, Yi Shi Ph.D. Biostatistics (2013) Chair, Lai Wei Ph.D. Biostatistics (2013) Chair, Bruck Adams, MPH Biostatistics Concentration (2012) Chair Jeff Rathbun, MA Biostatistics (2012) Committee Member, Wan-Min Tsai Ph.D. Biostatistics (2012) Committee Member, Tuochuan Dong, MA Biostatistics (2012) Committee Member, Chukwumere Nwogu, Ph.D. Roswell Park Graduate Division (2012) Committee Member, William Brady, Ph.D. Biostatistics (2012) Committee Member, Kristopher Attwood, Ph.D. Biostatistics (2012) Committee Member, Guogen Shan Ph.D. Biostatistics (2011) Outside Reader Abhijit Bhuyan, Tezpur University (2010)

47

Committee Member David Cavanaugh, M.A. Biostatistics (2010) Committee Member Rameela Chandrasekhar, Ph.D. Biostatistics (2011) Committee Member Wei Deng, Ph.D. Biostatistics (2011) Committee Member Vijay Jayaprakash, Ph.D. Cancer Prevention (2009) Chair, Dongliang Wang, Ph.D. Biostatistics (2010) Chair, Terry Mashtare, Ph.D. Biostatistics (2009) Chair, Owusu Asubonteng, Ph.D. Biostatistics (2009) Committee Member, Chung Chun Lin, Ph.D., Industrial Engineering (2010) Committee Member Xueya Cai, Ph.D. Biostatistics (2008) Committee Member Sylvia Quick, Ph.D. Biostatistics (2008) Committee Member Youngju Pak, Ph.D. Biostatistics (2007) Committee Member, Tania Das, MPH (emphasis in Biostatistics) (2006) Committee Member, Patricia Ng, M.S., Biomedical Sciences (2005) Project Advisor, Mark Legg, M. S. in Mathematics (2005) Committee Member, Jennifer Helferich, M.S. in Pharmacology And Toxicology (2004) Chair, David Lawrence, Ph.D. in Statistics (2004) Co-Chair, Patrick Bradshaw, M.Stat. in Statistics (2001) Co-Chair, Yongyi Min, Ph.D. in Statistics (2001) Committee Member, Jeffrey Thompson, Ph. D. in Statistics (2001) Committee Member, Ramona Greig, Ph.D. in Nursing (2001) Committee Member, Carrie Chapman, M.S. in Nutrition (2001) Committee Member, Judith Wolfe, M.S. in Nutrition (2001) Committee Member, Robert Duhaney, M.S. in Nutrition (2001) Committee Member, Dale Ostler, Ph. D. in Audiology (2000) Committee Member, Susan Keesling, M.S. in Nutrition (2000) Committee Member, Martin Ward, Ph.D. in Clinical Psychology (1996)