Ch 5 Alkyl Halides;

Substitution and Elimination reactions

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Is Organic Chemistry onlybased upon Memorization?

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No, Organic Chemistryis based upon Understanding!

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The Relationship between STRUCTURE and REACTIVITY

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The Relationship between STRUCTURE and REACTIVITY

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ALKYL HALIDES

SUBSTITUTION ELIMINATION

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Leaving group

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General Case

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reaction of a nucleophile and an alkyl halide

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reaction of a nucleophile and an alkyl halide

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Only alkyl halides with sp3 hybridized head carbons undergo nucleophilic subsitiution reactions

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What is(are) the major product(s) of the following reaction?

(A) (B)

(A) & (B)

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INVERSIONof stereochemistry

Stereochemistry of the reaction

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Rate of Reaction =

reactions have 2nd order Kinetics

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Tertiary alkyl halides DO NOT undergo reactions

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Rate of Reaction =

reactions have 1st order Kinetics

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What is(are) the major product(s) of the following reaction?

(A) & (B)

(A) (B)

ol ol

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