ALZENTAL Composition Suspension (1ml) 1 Tablet Al bend az ol e 20 mg 20 0 mg Properties and Mode of Action ALZENTAL, a benzimidazole carbamate derivative, is an anthelmintic with activity against most nematode and some otherworms. Activity against some larval stages and ova has also been demonstrated. ALZENTAL’s anthelmintic activity is considered to be dependent on the inhibition or destruction of cytoplasmic microtubules in the worm’s intestinal or absorptive cells. Inhibition of glucose uptake and depletion of glycogen stores follow as do other in hib itory effects Ieading to death of the worm. Indications ALZENTAL is a broad spectrum anthelmintic used in the treatmemt of single and mixed infections as: Enterobiasis Ascariasis Hookworms Trichuriasis Strongyloidiasis Taeniasis Capillariasis Cysticercosis Toxocariasis Trichostrongyliasis Trichinosis Echinococcosis (Hydatid disease) Dosage and Adm inistration Adults and Children Above 2 years of age: Enterobiasis, Ascariasis, Hookworm, Trichuriasis: 400 mg as a single dose. Treatment may be repeated in 3 weeks. Cysticercosis: 15 mg/kg body weight/day for 30 days. Strongyloidiasis and Taeniasis: 400 mg is given daily for 3 consecutive days. This may be repeated after 3 weeks if necessary. Capillariasis: 200 mg twice daily for 10 days. Echinococcosis (Hydatid disease): (Over 60 kg body weight): 800 mg/day in divided doses for 28 days. This is followed by 2 weeks drug free interval, to be repeated for 2-3 cycles. For inoperable cases up to 5 cycles may be given. http://www.eipico.com.eg/PRODUCT.ASP?id1=3&id2=0 &id4=1 1 of 2 3/2/2011 7:12 PM
