1. keratoconus 2. keratoglobus 3. pellucid marginal degeneration corneal ectasias

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1. Keratoconus

2. Keratoglobus

3. Pellucid marginal degeneration

CORNEAL ECTASIAS

Morphological classification of keratoconus

Nipple cone Oval cone Globus cone

Small and steep curvature Larger and ellipsoidal Largest

Signs of keratoconusBilateral in 85% but asymmetrical

Oil droplet reflex Prominent corneal nervesVogt striae

Acute hydrops Munson sign Fleischer ring & scarring

Bulging of lower lids on downgaze

Systemic associations of keratoconus

Crouzon syndromeMarfan syndrome Osteogenesis imperfecta

Atopic dermatitis Down syndrome Ehlers-Danlos syndrome

Keratoglobus

• Bilateral protrusion and thinning of entire cornea • Associations - Leber congenital amaurosis and blue sclera

• Onset usually at birth

Pellucid marginal degeneration

• Bilateral crescent-shaped inferior corneal thinning

• Onset between 20 and 40 years

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