2009 technology transfer annual report
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T E C H N O L O G Y T R A N S F E R
ADVANCING INNOVATION AND ENTREPRENEURSHIP
U T I N N O VAT I O N E N T E R P R I S E S
A N N U A L R E P O RT O N T E C H N O L O G Y T R A N S F E RFiscal Year 2009
Martin Abraham• Anovelsulfur-tolerantcatalystforsteamreformingofdiesel
andjetfuel
Malabala Adiga• Methodofplatingelectrocatalystforhydrogengeneration
Jared Anderson, Fei Zhao, Yunjing Meng, Zhao Qi Chao• Polymericionicliquidsasabsorbentcoatingsinsolidphase
microextraction
Ragheb Assaly, Joseph Shapiro, John Dignam• UseofPEG-Albuminasaplatformfordeliveryofantioxidant
andothermedications
Abdul-Majeed Azad• Carbondioxideandwater-basedfuelcells• HighTemperatureSulfurSorbents(ZSeries)• Carbondioxideandwater-basedfuelcells
Abdul-Majeed Azad, Desikan Sundararajan• Exhaustgaspurificationcatalysts• Acetylenegassensor
Michael Bisesi, Christopher Bork, Paul Rega • Cot-AID(AssistiveIntegratedDevices)(11separatedevicesdisclosed)
Ashok Biyani• Modifiedpediclescrewtipforone-steppercutaneousinsertion• Unidirectionalrotarypediclescrewforcorrectionofspinaldeformity
ingrowingchildren• Directionalsofttissuedilatorsanddockingpinwithintegratedlight
sourceforoptimizationofretractorplacementinminimallyinvasivespinesurgery
• Derotationpediclescrewdesignforsurgicalcorrectionofspinaldeformity
• Fixedandpreloadcompressioncervicalplateswithandwithoutintegratedlockingmechanism
• Posteriorfixationdeviceforpercutaneousstabilizationofthoracolumbarburstfractures
• Expandablecorpectomycageconcept
Ashok Biyani, Philip Nowicki• Femoralneckwasherfixationsystem
Ashok Biyani, Brian Blessinger• Anintegrateddeviceforstorageanddeliveryofbonegraftor
implantablematerial
Ashok Biyani, Gary Durivage• AdjustableHeightPedicleScrew
Christopher Bork• Anergonomichandleforrollingluggage
Thomas Cable, John Setlock• Reformerdesignusingsymmetrical,oxygenconductivemembranes
Brent Cameron, Scott Pappada• Aneuralnetworkbasedapproachforphysiologicalglycemic
forecasting
George Cicila, Soon Jin Lee, Justin Ways• Congenicratstrains(6separatestrainsdisclosed)
Maria Coleman, Hamidreza Hakimelahi, Javed Mapkar• Functionalnanocompositenetworkforreverseselectivemembranes
Alvin Compaan• RapidthermalactivationofflexibleCdTecellsandmodules• Methodtoimproveadhesionofthin-filmsolarcellcoatingsto
polymerfilm• MethodtomakeflexibleCdTemodulesonpolymercastonstainless
steelwebforroll-to-rollmanufacturing
Christopher Cooper• Vascularqualityassurance
Xunming Deng, Qi Hua Fan, Shiban Zhang• PulsedDCreactivesputteringdepositionofzincoxidethinfilmsfrom
zincmetaltarget
Michael Dennis, Dean Walton• ScatterreductioninEPIDradiography
John Dismukes, Lawrence Miller, John Bers• ARImethodologyandscorecardtoolforacceleratingbreakthrough
innovations
Mohammad Elahinia, James Maloney, Majid Tabesh, Richard Yeasting• Bio-inspiredshapememoryalloyesophaguspositioner
Mohammad Elahinia, Vijay Goel, Majid Tabesh• Bio-inspiredshapememoryalloypediclescrewtocompensateforbone
degradationinosteoporosispatients
Mohammad Elahinia, The Nguyen• Mixed-modesemiactivemagnetorheologicalmount
Qi Hua Fan, Xianbo Liao, Xunming Deng, Xianbi Xiang• Highefficiencythinfilmsolarcellsmadewithgradedlightabsorber
materials
Vijay Goel, Hossein Elgafy, Ahmad Faizan• Cervicalspineposteriordynamicsysteminconjunctionwithanartificial
disctotreatthewhiplashinjurypatients
Vijay Goel, Aaron Matyas• Anchoringpediclescrew• Minimallyinvasivecollapsiblecage
Miles Hacker• Usinginactiveanti-cancerdrugstotreatcysticfibrosis
Marthe Howard• Innovativenewtreatmentstrategyforglioma
Dragan Isailovic• Florophore-assistedlaserdesorptionionizationmassspectrometry
(FALDI-MS)
Samer Khouri, Sonia Najjar• Novelmodelofthemetabolicsyndromewithassociatedspontaneous
atherosclerosis
Dong-Shik Kim, Maria Coleman• SuspensiontechniqueforGochangyellowclay
Tony Koesters, Brian Kanney, Ryan Kremer, Allan Gindy, Faisal Bukhari• BurnableShreddedPaperLogs
Yun-Ming Lin• Reactionrateaccelerationviaasymmetricbifunctionalcatalysis
Terri Lombardo• Novelrenewableelectricenergy
Ioan Marinescu• Penetratingcompoundswithvariableproperties
Mark Mason• Newtrianionicligandsforconstrainedgeometrycatalysts
Udayan Nadkeolyar• Pilotfreehighspeedsurfacetransportationcapsule
Philip Nowicki, Ashok Biyani, Martin Skie• Antibioticclusteredpercutaneouspincoversystem
Thomas Papadimos• Thebeneficialeffectsofinhalednitricoxideinpatientswithsevere
traumaticbraininjurycomplicatedbyacuterespiratorydistresssyndrome
Invention DisclosuresCatherine Powell• MARKtheSpot–Answersonthespot• Backlace
Carmen Quatman, Andrew Maszaros, Catherine Quatman• Shoulderbracefordecreasedpassiverestraints
Martin Rice• Learningtotelltimeusingknowledgeofresults
Edwin Sanchez, Garrett Heinrich, Terry Hinds• Discoveryofglucocorticoidreceptorbetainmice
Rebecca Schneider• ALearningCommunityofTeachers(ALCOT)
Steven Selman, Hinman Channing• Applicationsofcobratoxinandderivatives
Lirim Shemshedini, Changmeng Cai, Shao-Yong Chen, Chen-Lin Hsieh• Solubleguanylylcyclasealpha1(sGCalpha1)asanoveldiagnostic
markerofandthereapeutictargetforprostatecancer• V94Cells:Anovelandrogen-independentLNCaPcellline
Krishna Shenai, Nikhil Gudi, Dhakshina Thavamani• Anovelhybridthermoelectricenergyconverter(TEC)andphotovoltaic
(PV)system
Krishna Shenai, Nikhil Gudi, Dhakshina Thavamani, Premchand Boyapati, Prashanth Reddy• HybridsmartmodularDCpowersystem
Krishna Shenai, Nikhil Gudi• Wirelesssmartmovableantenna• Remotelycontrollablesmartwidebandwirelessantenna• Smartwirelesslytunablecommunicationsystempowerfrom
renewableenergysources
Krishna Shenai, Ashok Biyani, Vijay Goel, Vijay Devabhaktuni, Bradford Lilly• Anovelprocedureandapparatusforperforminghighly
accuratesurgery
Krishna Shenai, Premchand Boyapati, Dhakshina Thavamani, Jessica Jordan• Novelwirelesssensorcommunicationusingsoundwaves
Krishna Shenai, Premchand Boyapati• Multi-functionlow-powerwirelessairsensor• Smartremotesensingandwirelessinformationmanagement• Anovelwirelesssensorsystemforstructuralhealthmonitoring
Krishna Shenai, Bradford Lilly, Premchand Boyapati• Automatedswimmingpoolmanagementsystem• Amethodforpreciseintelligentsoilchemicaldistribution
Thomas Stuart• Amodularizedsystemwithrelaysformanagingseriesconnected
batterycells
Zi-Jian Xie Jiang Tian• Na/K-ATPaseexpressionasanindicatorfortreatmentofcancer
Zi-Jian Xie, Joseph Shapiro, Zhichuan Li• Na/K-ATPase-derivedpeptidesasantagonistofCTSandas
therapeuticagentsforcancer
Daniel Kory, Ph.D., MBAAssociate Vice President for Technology TransferPhone: 419.383.6924Email: daniel.kory@utoledo.edu
Stephen Snider, J.D.Director, Technology Licensing & Contracts Phone: 419.383.6963
Email: stephen.snider@utoledo.edu
Mark Fox, J.D., MSPatent Technology AssociatePhone: 419.383.6907Email: mark.fox@utoledo.edu
Samuel Giles, MBAPatent Licensing AssociatePhone: 419.383.6965Email: samuel.giles3@utoledo.edu
Sandra RhoadesIP AdministratorPhone: 419.383.6923Email: sandy.rhoades@utoledo.edu
Contacts
INNOVATIONENTERPRISES
INNOVATIONENTERPRISES
W W W. U T O L E D O . E D U / R E S E A R C H / T E C H T R A N S F E R
IR 1
92 1
009
250
In2009,UTInnovationEnterpriseswascreatedtodiversifyandtransformtheregionaleconomybyfacilitatingthedevelopmentandattractionofscienceandtechnology-basedorganizations.Bybringingtogetherresearchdevelopment,technologytransfer,incubation,workforcedevelopmentandtheScienceandTechnologyCorridor,theUniversitybelievesitwillbeabletoenhancetheglobalcompetitivenessofNWOhio.
The University of Toledo has made a significant commitment to improve the human condition by taking a leadership role in regional economic development. To enable and strengthen these efforts, the University has taken major steps to build up the technology transfer program by adding new staff members to (i) assist in identifying and licensing new technologies and (ii) help develop new spin-off businesses. Lloyd Jacobs, M.D., President of the University, has clearly articulated that the technology transfer group is a core University unit performing highly valued functions with an established ability to identify and license new technologies and create spin-off businesses that result in jobs, economic development and wealth creation. In 2008, Innovation Associates reported in a project funded by the National Science Foundation, based on data from the Association of University Technology Managers (AUTM) that, among US universities, UT ranked 6th in executing licenses and 7th in launching start-up businesses, when taking the level of research expenditures into account — an indication of a very high level productivity in the translation of research into economic development. The US average for invention disclosures per $10 MM of research expenditures is 4.3. UT is significantly higher, increasing from 5.8 to 16 in the past seven years. The number of new license agreements per $10 MM of research expenditures has also increased steadily from 2003 to 2009, from 1.2 to 3.8, versus a national average of 0.4. According to AUTM, the average US University spins-off one business for every $100 MM in research expenditures. At two per year, UT is four times the national average and at three per year, the results in 2007 to 2009, UT is six times the national average. UT now has 16 active spin-off businesses, generating about 100 local technology positions. Several have attracted $1 million + in third party validation funding. Three spin-offs have received funding from Regional Growth Partnership’s Rocket Ventures and four have qualified for the Regional Growth Partnership’s Ignite Program. We look forward to continuing to work closely with the faculty on innovative and entrepreneurial ideas. We believe that the faculty’s continued participation will help us increase UT’s state-wide and national profile as an innovation system that produces new discoveries, new products and/or services, new firms, jobs, and wealth creation.
RichardAndaloroDonaldAngelbeckBernardArulanandamRaghebAssalyBradleyAustermillerKennethBachmannJamesBarilGloriaBorgstahlMichaelBrattainReneeBuchananJeffreyBurnhamJamesByersBrentCameronYangCaoKemingChenXiaChenGarryColeAlvinCompaanErinCrawfordJulianDaviesRobertDeckLaurentDelouxJefferyDeMuthXunmingDengJohnDignamPhilipDunbarGrahamDurantSylvainDutremezPaulErhardtErvinFaulmannRonaldFournierPeterFraleighJamesFryKuan-ChenFuJamesGanoGretaGarboDeanGiolandoVijayGoelPeterGoldblattStephenGoldmanBingGongAnneGravesAkhleshGupta
JiwanGuptaGeorgeHageageJamesHamptonGregoryHaselhuhnJudyHendricksJamesHornerWayneHossRichardHudsonChiung-YuHungJamesHuttnerClaraJacksonDouglasJambard-SweetJerzyJankunRalphJansenVictorKarpovStamatiosKartalopoulosPeterKascakRickKeckAminKhanRogerKingJonKirchhoffThoeKirklandIIIRitaKleinWieslawKlisCharlesKnightStevenKramerKennethKroppFrederickKurtzHaroldLeeAkliluLemmaMarcLevineJeffreyLovelaceEdwardLumsdaineXiandaMaKonstantinMakhratchevMauriceManningWilliamMesserJr.DennisMetzgerAlanMorganNaserMostaghelDurgeshNadkarniGanapathyNaganathanTerryNg
BabatundeOjoHenryPovolnyKentPriceDemetriosRaftopoulosWalajapetRajeswaranGlennReimerWilliamRollYannRoussillonSairamRudrabhatlaJeffreySabinMurraySaffranJeffreySarverPadmanabhanSekherStevenSelmanKalpathiSeshanJosephShapiroDianaShvydkaHenrySimonDimitrisSkalkosJamesSlamaCliffordSmithEdwardSnellMorrisSrebnikSujathaSrinivasanThomasStuartVernerSwansonSridharThirupathiLiyanaaratchingeTillekeratneJamesTrempeStefanUhlenbrockSasidharVaranasiYuWangDavidWeaverJamesWilleyJianminXueQichengYangZhongYeJieh-JuenYuQuilinYuBinZhengDonaldZrudsky
Gene ExpressJim WilleyJune 1998 Agenomicsbiotechcompanyprovidinggeneassaystoassistpharmaceuticalandbiotechcompanieswithdrugdevelopmentandexpressionanalysis.
Schneider & Morse Group Roy Schneider and Dennis Morse April 2001 Astart-upfocusedondevelopingcomputer-basededucationaltoolsforanimalanatomyanddissection
Mithridion Wayne Hoss and Bill Messer January 2002 Anemergingbiotechcompanyfocusedonthediscoveryandcommercializationoftreatmentsforneurologicalandpsychiatricdiseases
Innovative Thin Films, Ltd. Dean Giolando March 2004 Acompanyfocusedonprovidingthinfilmsolutionstoproblemsassociatedwiththephotovoltaicindustrysuchasscratching,soilingandreflection
Hi-Genomics Stephen Goldman and Sairam Rudrabhatla April 2004 Avirtualcompanywithtechnologiesintissuecultureandgenetictransformationthatcouplehighoutput,rapid,genotypeindependentregenerationtohighfrequencyDNAtransferusingeitheragrobacteriumorbiolistictransformation
The Turning Point Vijay Goel, Danny Pincivero, John Jaegly, and David Dick June 2005 Amanufacturingandmarketingfirmthatproducesastate-of-the-artgolfexerciseandtherapeuticdevice
Xunlight Xunming Deng January 2006 Amanufacturingandmarketingcompanythatdevelopsthin-filmsiliconbasedphotovoltaicproductsandmanufacturingequipmentforhigh-throughputproductionofflexibleandlightweightphotovoltaicmodulesatlowcost
Spinal DesignsAshok Biyani May 2006 Amarketingfirmthatprovidesproductsandservicestoorthopedicsurgeons.
Freedom Meditech Brent Cameron December 2006 Adevelopmentalstagemedicaldevicecompanyfocusedonthenon-invasivebloodglucosetestingfordiabetics
Suganit Systems Sasidhar Varanasi, Connie Schall, Jared Anderson, and Patricia Relue March 2007 Astart-upcompanyinvolvedintheresearchanddevelopmentofrenewableandcleanenergywithafocusinethanolproductionfrombiomass
ADS Biotechnology, Joseph Shapiro, David Dignam, and Ragheb Assaly January 2008 Revolutionaryapproachforthetreatmentofthreateningclinicalconditions.Thecompany’sprimaryproduct,pegylatedalbumin,isatherapeuticcolloid-typebloodvolumeexpanderagentthatissuperiortohumanserumalbumin
Esclapeus Biopharaceuticals KV Chin May 2008Start-upfocusedondevelopingasmallmoleculeinterventionforobesity,oneofthemostseriouspublichealthrisksintheUSandworldwide
Innovative Water Technologies Dean Giolando May 2008Developingaflashevaporationspraytechnologyforthepurificationand/ordesalinationofwater
Xunlight Solar-26 Al Compaan December 2008DevelopingCdTethin-filmphotovoltaicsonpolyimidesubstrates
Total Compliance Abdul-Majeed Azad February 2009 Start-upplanningtocommercializetechnologyfortheremovalofcarbonmonoxide,organiccompoundsandunburnedhydrocarbonsfromthestreamofcombustiondevicesand/orspraybooths.
JWH Group Abdul-Majeed Azad April 2009Start-upcompanythatisdevelopinggassensortechnology
The University would like to recognize the following University inventors’ contributions in promoting the progress of science through designation as an inventor on one or more patent grants. Names in red are new additions to the list for fiscal year 2009. ADSBiotechnology,Ltd,aUTspin-offcompany,isworking
tocommercializeanewmedicaltreatment,polyethylene-glycol (PEG)-modified albumin, which works to expandblood’svolumesoitwillnotescapeasmayoccurinvariousmedical scenarios where a patient’s blood vessels leak.The company worked with RocketVentures to organizeand secure funding, including a recent investment of$250,000.ADShas submitted applications for grants totheU.S.DepartmentofDefense,theNationalInstitutesofHealth,andtheClevelandClinic.
SuGanitSystems,Inc.,astart-upcompanyresearchingand developing renewable clean energy, acquiredexclusivelicensetotwoUniversityofToledotechnologiesfor producing ethanol from cellulosic biomass. Thecompany has been awarded over $2.1M in fundingfrom the US Department of Energy, USDA, and Ohio’sThird Frontier Advanced Energy Program to developthese technologies. SuGanit is scaling up the licensedtechnologyandisplanningtobuildapilotscalecellulosicethanolfacilityinToledo,Ohio.
Mithridion, Inc. merged with the UT spin-off CognitivePharmaceuticals to develop drugs for neurologicalandpsychiatricdiseases.Thecompanyhasraised$7.4milliontodateinequityfundingandrecentlyannouncedthe results of its Phase I pharmacokinetic and clinicalstudyofMCD-386,itsleaddrugcandidateforAlzheimer’sdisease. The study produced encouraging results andMithridion is continuing todevelop thedrug for furtherPhaseIstudies.
Xunlight Corporation, a University of Toledo technologyspin-off,develops,manufactures,andmarketsphotovoltaicmodulesthatconvertsunlightintoelectricity.Thecompanyhascompletedinstallingitsfirstfull-scaleproductionline,andmadeitsfirstproductiondeliverytoTheUniversityofToledo. Xunlight recently received the Red Herring 100NorthAmericaAward,honoringthemostpromisingprivatetechnology companies, and the AlwaysOn GoingGreenEast 50 Award, honoring the top private companies incleantechpursuingextraordinaryinnovations.
Start-up ActivityInventors
TheFacultyatTheUniversityofToledohascontinuedtoembracetheUniversity’smissiontoimprovethehumancondition.Asaresult,ourofficesawa59percentincreaseinthenumberofinventiondisclosuressubmitted,whichresultedinadditionallicenses,start-upcompanies,andrevenues.
Medical 47%
Pharmacy1%
Arts & Sciences13%
Engineering 37%
Education1%
Business1%
Industry Sponsored Research, Material Transfer, and Confidentiality Agreements
108
145155
177
139
175
203
0
50
100
150
200
250
FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009
Invention Disclosures
24
34 35 3833
54
91
0
10
20
30
40
50
60
70
80
90
100
FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY2009
Licensing Revenue
$150,434
$337,423
$901,114
$524,575
$865,018$939,307
$1,004,000
$0$200,000
$400,000
$600,000
$800,000
$1,000,000
$1,200,000
FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009
$1,200,000
$1,000,000
$800,000
$600,000
$400,000
$200,000
$0
Deals (Licenses and Options)
5
8
12
7
19
12
22
-
5
10
15
20
25
FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009
The University of Toledo has made a significant commitment to improve the human condition by taking a leadership role in regional economic development. To enable and strengthen these efforts, the University has taken major steps to build up the technology transfer program by adding new staff members to (i) assist in identifying and licensing new technologies and (ii) help develop new spin-off businesses. Lloyd Jacobs, M.D., President of the University, has clearly articulated that the technology transfer group is a core University unit performing highly valued functions with an established ability to identify and license new technologies and create spin-off businesses that result in jobs, economic development and wealth creation. In 2008, Innovation Associates reported in a project funded by the National Science Foundation, based on data from the Association of University Technology Managers (AUTM) that, among US universities, UT ranked 6th in executing licenses and 7th in launching start-up businesses, when taking the level of research expenditures into account — an indication of a very high level productivity in the translation of research into economic development. The US average for invention disclosures per $10 MM of research expenditures is 4.3. UT is significantly higher, increasing from 5.8 to 16 in the past seven years. The number of new license agreements per $10 MM of research expenditures has also increased steadily from 2003 to 2009, from 1.2 to 3.8, versus a national average of 0.4. According to AUTM, the average US University spins-off one business for every $100 MM in research expenditures. At two per year, UT is four times the national average and at three per year, the results in 2007 to 2009, UT is six times the national average. UT now has 16 active spin-off businesses, generating about 100 local technology positions. Several have attracted $1 million + in third party validation funding. Three spin-offs have received funding from Regional Growth Partnership’s Rocket Ventures and four have qualified for the Regional Growth Partnership’s Ignite Program. We look forward to continuing to work closely with the faculty on innovative and entrepreneurial ideas. We believe that the faculty’s continued participation will help us increase UT’s state-wide and national profile as an innovation system that produces new discoveries, new products and/or services, new firms, jobs, and wealth creation.
RichardAndaloroDonaldAngelbeckBernardArulanandamRaghebAssalyBradleyAustermillerKennethBachmannJamesBarilGloriaBorgstahlMichaelBrattainReneeBuchananJeffreyBurnhamJamesByersBrentCameronYangCaoKemingChenXiaChenGarryColeAlvinCompaanErinCrawfordJulianDaviesRobertDeckLaurentDelouxJefferyDeMuthXunmingDengJohnDignamPhilipDunbarGrahamDurantSylvainDutremezPaulErhardtErvinFaulmannRonaldFournierPeterFraleighJamesFryKuan-ChenFuJamesGanoGretaGarboDeanGiolandoVijayGoelPeterGoldblattStephenGoldmanBingGongAnneGravesAkhleshGupta
JiwanGuptaGeorgeHageageJamesHamptonGregoryHaselhuhnJudyHendricksJamesHornerWayneHossRichardHudsonChiung-YuHungJamesHuttnerClaraJacksonDouglasJambard-SweetJerzyJankunRalphJansenVictorKarpovStamatiosKartalopoulosPeterKascakRickKeckAminKhanRogerKingJonKirchhoffThoeKirklandIIIRitaKleinWieslawKlisCharlesKnightStevenKramerKennethKroppFrederickKurtzHaroldLeeAkliluLemmaMarcLevineJeffreyLovelaceEdwardLumsdaineXiandaMaKonstantinMakhratchevMauriceManningWilliamMesserJr.DennisMetzgerAlanMorganNaserMostaghelDurgeshNadkarniGanapathyNaganathanTerryNg
BabatundeOjoHenryPovolnyKentPriceDemetriosRaftopoulosWalajapetRajeswaranGlennReimerWilliamRollYannRoussillonSairamRudrabhatlaJeffreySabinMurraySaffranJeffreySarverPadmanabhanSekherStevenSelmanKalpathiSeshanJosephShapiroDianaShvydkaHenrySimonDimitrisSkalkosJamesSlamaCliffordSmithEdwardSnellMorrisSrebnikSujathaSrinivasanThomasStuartVernerSwansonSridharThirupathiLiyanaaratchingeTillekeratneJamesTrempeStefanUhlenbrockSasidharVaranasiYuWangDavidWeaverJamesWilleyJianminXueQichengYangZhongYeJieh-JuenYuQuilinYuBinZhengDonaldZrudsky
Gene ExpressJim WilleyJune 1998 Agenomicsbiotechcompanyprovidinggeneassaystoassistpharmaceuticalandbiotechcompanieswithdrugdevelopmentandexpressionanalysis.
Schneider & Morse Group Roy Schneider and Dennis Morse April 2001 Astart-upfocusedondevelopingcomputer-basededucationaltoolsforanimalanatomyanddissection
Mithridion Wayne Hoss and Bill Messer January 2002 Anemergingbiotechcompanyfocusedonthediscoveryandcommercializationoftreatmentsforneurologicalandpsychiatricdiseases
Innovative Thin Films, Ltd. Dean Giolando March 2004 Acompanyfocusedonprovidingthinfilmsolutionstoproblemsassociatedwiththephotovoltaicindustrysuchasscratching,soilingandreflection
Hi-Genomics Stephen Goldman and Sairam Rudrabhatla April 2004 Avirtualcompanywithtechnologiesintissuecultureandgenetictransformationthatcouplehighoutput,rapid,genotypeindependentregenerationtohighfrequencyDNAtransferusingeitheragrobacteriumorbiolistictransformation
The Turning Point Vijay Goel, Danny Pincivero, John Jaegly, and David Dick June 2005 Amanufacturingandmarketingfirmthatproducesastate-of-the-artgolfexerciseandtherapeuticdevice
Xunlight Xunming Deng January 2006 Amanufacturingandmarketingcompanythatdevelopsthin-filmsiliconbasedphotovoltaicproductsandmanufacturingequipmentforhigh-throughputproductionofflexibleandlightweightphotovoltaicmodulesatlowcost
Spinal DesignsAshok Biyani May 2006 Amarketingfirmthatprovidesproductsandservicestoorthopedicsurgeons.
Freedom Meditech Brent Cameron December 2006 Adevelopmentalstagemedicaldevicecompanyfocusedonthenon-invasivebloodglucosetestingfordiabetics
Suganit Systems Sasidhar Varanasi, Connie Schall, Jared Anderson, and Patricia Relue March 2007 Astart-upcompanyinvolvedintheresearchanddevelopmentofrenewableandcleanenergywithafocusinethanolproductionfrombiomass
ADS Biotechnology, Joseph Shapiro, David Dignam, and Ragheb Assaly January 2008 Revolutionaryapproachforthetreatmentofthreateningclinicalconditions.Thecompany’sprimaryproduct,pegylatedalbumin,isatherapeuticcolloid-typebloodvolumeexpanderagentthatissuperiortohumanserumalbumin
Esclapeus Biopharaceuticals KV Chin May 2008Start-upfocusedondevelopingasmallmoleculeinterventionforobesity,oneofthemostseriouspublichealthrisksintheUSandworldwide
Innovative Water Technologies Dean Giolando May 2008Developingaflashevaporationspraytechnologyforthepurificationand/ordesalinationofwater
Xunlight Solar-26 Al Compaan December 2008DevelopingCdTethin-filmphotovoltaicsonpolyimidesubstrates
Total Compliance Abdul-Majeed Azad February 2009 Start-upplanningtocommercializetechnologyfortheremovalofcarbonmonoxide,organiccompoundsandunburnedhydrocarbonsfromthestreamofcombustiondevicesand/orspraybooths.
JWH Group Abdul-Majeed Azad April 2009Start-upcompanythatisdevelopinggassensortechnology
The University would like to recognize the following University inventors’ contributions in promoting the progress of science through designation as an inventor on one or more patent grants. Names in red are new additions to the list for fiscal year 2009. ADSBiotechnology,Ltd,aUTspin-offcompany,isworking
tocommercializeanewmedicaltreatment,polyethylene-glycol (PEG)-modified albumin, which works to expandblood’svolumesoitwillnotescapeasmayoccurinvariousmedical scenarios where a patient’s blood vessels leak.The company worked with RocketVentures to organizeand secure funding, including a recent investment of$250,000.ADShas submitted applications for grants totheU.S.DepartmentofDefense,theNationalInstitutesofHealth,andtheClevelandClinic.
SuGanitSystems,Inc.,astart-upcompanyresearchingand developing renewable clean energy, acquiredexclusivelicensetotwoUniversityofToledotechnologiesfor producing ethanol from cellulosic biomass. Thecompany has been awarded over $2.1M in fundingfrom the US Department of Energy, USDA, and Ohio’sThird Frontier Advanced Energy Program to developthese technologies. SuGanit is scaling up the licensedtechnologyandisplanningtobuildapilotscalecellulosicethanolfacilityinToledo,Ohio.
Mithridion, Inc. merged with the UT spin-off CognitivePharmaceuticals to develop drugs for neurologicalandpsychiatricdiseases.Thecompanyhasraised$7.4milliontodateinequityfundingandrecentlyannouncedthe results of its Phase I pharmacokinetic and clinicalstudyofMCD-386,itsleaddrugcandidateforAlzheimer’sdisease. The study produced encouraging results andMithridion is continuing todevelop thedrug for furtherPhaseIstudies.
Xunlight Corporation, a University of Toledo technologyspin-off,develops,manufactures,andmarketsphotovoltaicmodulesthatconvertsunlightintoelectricity.Thecompanyhascompletedinstallingitsfirstfull-scaleproductionline,andmadeitsfirstproductiondeliverytoTheUniversityofToledo. Xunlight recently received the Red Herring 100NorthAmericaAward,honoringthemostpromisingprivatetechnology companies, and the AlwaysOn GoingGreenEast 50 Award, honoring the top private companies incleantechpursuingextraordinaryinnovations.
Start-up ActivityInventors
TheFacultyatTheUniversityofToledohascontinuedtoembracetheUniversity’smissiontoimprovethehumancondition.Asaresult,ourofficesawa59percentincreaseinthenumberofinventiondisclosuressubmitted,whichresultedinadditionallicenses,start-upcompanies,andrevenues.
Medical 47%
Pharmacy1%
Arts & Sciences13%
Engineering 37%
Education1%
Business1%
Industry Sponsored Research, Material Transfer, and Confidentiality Agreements
108
145155
177
139
175
203
0
50
100
150
200
250
FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009
Invention Disclosures
24
34 35 3833
54
91
0
10
20
30
40
50
60
70
80
90
100
FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY2009
Licensing Revenue
$150,434
$337,423
$901,114
$524,575
$865,018$939,307
$1,004,000
$0$200,000
$400,000
$600,000
$800,000
$1,000,000
$1,200,000
FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009
$1,200,000
$1,000,000
$800,000
$600,000
$400,000
$200,000
$0
Deals (Licenses and Options)
5
8
12
7
19
12
22
-
5
10
15
20
25
FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009
The University of Toledo has made a significant commitment to improve the human condition by taking a leadership role in regional economic development. To enable and strengthen these efforts, the University has taken major steps to build up the technology transfer program by adding new staff members to (i) assist in identifying and licensing new technologies and (ii) help develop new spin-off businesses. Lloyd Jacobs, M.D., President of the University, has clearly articulated that the technology transfer group is a core University unit performing highly valued functions with an established ability to identify and license new technologies and create spin-off businesses that result in jobs, economic development and wealth creation. In 2008, Innovation Associates reported in a project funded by the National Science Foundation, based on data from the Association of University Technology Managers (AUTM) that, among US universities, UT ranked 6th in executing licenses and 7th in launching start-up businesses, when taking the level of research expenditures into account — an indication of a very high level productivity in the translation of research into economic development. The US average for invention disclosures per $10 MM of research expenditures is 4.3. UT is significantly higher, increasing from 5.8 to 16 in the past seven years. The number of new license agreements per $10 MM of research expenditures has also increased steadily from 2003 to 2009, from 1.2 to 3.8, versus a national average of 0.4. According to AUTM, the average US University spins-off one business for every $100 MM in research expenditures. At two per year, UT is four times the national average and at three per year, the results in 2007 to 2009, UT is six times the national average. UT now has 16 active spin-off businesses, generating about 100 local technology positions. Several have attracted $1 million + in third party validation funding. Three spin-offs have received funding from Regional Growth Partnership’s Rocket Ventures and four have qualified for the Regional Growth Partnership’s Ignite Program. We look forward to continuing to work closely with the faculty on innovative and entrepreneurial ideas. We believe that the faculty’s continued participation will help us increase UT’s state-wide and national profile as an innovation system that produces new discoveries, new products and/or services, new firms, jobs, and wealth creation.
RichardAndaloroDonaldAngelbeckBernardArulanandamRaghebAssalyBradleyAustermillerKennethBachmannJamesBarilGloriaBorgstahlMichaelBrattainReneeBuchananJeffreyBurnhamJamesByersBrentCameronYangCaoKemingChenXiaChenGarryColeAlvinCompaanErinCrawfordJulianDaviesRobertDeckLaurentDelouxJefferyDeMuthXunmingDengJohnDignamPhilipDunbarGrahamDurantSylvainDutremezPaulErhardtErvinFaulmannRonaldFournierPeterFraleighJamesFryKuan-ChenFuJamesGanoGretaGarboDeanGiolandoVijayGoelPeterGoldblattStephenGoldmanBingGongAnneGravesAkhleshGupta
JiwanGuptaGeorgeHageageJamesHamptonGregoryHaselhuhnJudyHendricksJamesHornerWayneHossRichardHudsonChiung-YuHungJamesHuttnerClaraJacksonDouglasJambard-SweetJerzyJankunRalphJansenVictorKarpovStamatiosKartalopoulosPeterKascakRickKeckAminKhanRogerKingJonKirchhoffThoeKirklandIIIRitaKleinWieslawKlisCharlesKnightStevenKramerKennethKroppFrederickKurtzHaroldLeeAkliluLemmaMarcLevineJeffreyLovelaceEdwardLumsdaineXiandaMaKonstantinMakhratchevMauriceManningWilliamMesserJr.DennisMetzgerAlanMorganNaserMostaghelDurgeshNadkarniGanapathyNaganathanTerryNg
BabatundeOjoHenryPovolnyKentPriceDemetriosRaftopoulosWalajapetRajeswaranGlennReimerWilliamRollYannRoussillonSairamRudrabhatlaJeffreySabinMurraySaffranJeffreySarverPadmanabhanSekherStevenSelmanKalpathiSeshanJosephShapiroDianaShvydkaHenrySimonDimitrisSkalkosJamesSlamaCliffordSmithEdwardSnellMorrisSrebnikSujathaSrinivasanThomasStuartVernerSwansonSridharThirupathiLiyanaaratchingeTillekeratneJamesTrempeStefanUhlenbrockSasidharVaranasiYuWangDavidWeaverJamesWilleyJianminXueQichengYangZhongYeJieh-JuenYuQuilinYuBinZhengDonaldZrudsky
Gene ExpressJim WilleyJune 1998 Agenomicsbiotechcompanyprovidinggeneassaystoassistpharmaceuticalandbiotechcompanieswithdrugdevelopmentandexpressionanalysis.
Schneider & Morse Group Roy Schneider and Dennis Morse April 2001 Astart-upfocusedondevelopingcomputer-basededucationaltoolsforanimalanatomyanddissection
Mithridion Wayne Hoss and Bill Messer January 2002 Anemergingbiotechcompanyfocusedonthediscoveryandcommercializationoftreatmentsforneurologicalandpsychiatricdiseases
Innovative Thin Films, Ltd. Dean Giolando March 2004 Acompanyfocusedonprovidingthinfilmsolutionstoproblemsassociatedwiththephotovoltaicindustrysuchasscratching,soilingandreflection
Hi-Genomics Stephen Goldman and Sairam Rudrabhatla April 2004 Avirtualcompanywithtechnologiesintissuecultureandgenetictransformationthatcouplehighoutput,rapid,genotypeindependentregenerationtohighfrequencyDNAtransferusingeitheragrobacteriumorbiolistictransformation
The Turning Point Vijay Goel, Danny Pincivero, John Jaegly, and David Dick June 2005 Amanufacturingandmarketingfirmthatproducesastate-of-the-artgolfexerciseandtherapeuticdevice
Xunlight Xunming Deng January 2006 Amanufacturingandmarketingcompanythatdevelopsthin-filmsiliconbasedphotovoltaicproductsandmanufacturingequipmentforhigh-throughputproductionofflexibleandlightweightphotovoltaicmodulesatlowcost
Spinal DesignsAshok Biyani May 2006 Amarketingfirmthatprovidesproductsandservicestoorthopedicsurgeons.
Freedom Meditech Brent Cameron December 2006 Adevelopmentalstagemedicaldevicecompanyfocusedonthenon-invasivebloodglucosetestingfordiabetics
Suganit Systems Sasidhar Varanasi, Connie Schall, Jared Anderson, and Patricia Relue March 2007 Astart-upcompanyinvolvedintheresearchanddevelopmentofrenewableandcleanenergywithafocusinethanolproductionfrombiomass
ADS Biotechnology, Joseph Shapiro, David Dignam, and Ragheb Assaly January 2008 Revolutionaryapproachforthetreatmentofthreateningclinicalconditions.Thecompany’sprimaryproduct,pegylatedalbumin,isatherapeuticcolloid-typebloodvolumeexpanderagentthatissuperiortohumanserumalbumin
Esclapeus Biopharaceuticals KV Chin May 2008Start-upfocusedondevelopingasmallmoleculeinterventionforobesity,oneofthemostseriouspublichealthrisksintheUSandworldwide
Innovative Water Technologies Dean Giolando May 2008Developingaflashevaporationspraytechnologyforthepurificationand/ordesalinationofwater
Xunlight Solar-26 Al Compaan December 2008DevelopingCdTethin-filmphotovoltaicsonpolyimidesubstrates
Total Compliance Abdul-Majeed Azad February 2009 Start-upplanningtocommercializetechnologyfortheremovalofcarbonmonoxide,organiccompoundsandunburnedhydrocarbonsfromthestreamofcombustiondevicesand/orspraybooths.
JWH Group Abdul-Majeed Azad April 2009Start-upcompanythatisdevelopinggassensortechnology
The University would like to recognize the following University inventors’ contributions in promoting the progress of science through designation as an inventor on one or more patent grants. Names in red are new additions to the list for fiscal year 2009. ADSBiotechnology,Ltd,aUTspin-offcompany,isworking
tocommercializeanewmedicaltreatment,polyethylene-glycol (PEG)-modified albumin, which works to expandblood’svolumesoitwillnotescapeasmayoccurinvariousmedical scenarios where a patient’s blood vessels leak.The company worked with RocketVentures to organizeand secure funding, including a recent investment of$250,000.ADShas submitted applications for grants totheU.S.DepartmentofDefense,theNationalInstitutesofHealth,andtheClevelandClinic.
SuGanitSystems,Inc.,astart-upcompanyresearchingand developing renewable clean energy, acquiredexclusivelicensetotwoUniversityofToledotechnologiesfor producing ethanol from cellulosic biomass. Thecompany has been awarded over $2.1M in fundingfrom the US Department of Energy, USDA, and Ohio’sThird Frontier Advanced Energy Program to developthese technologies. SuGanit is scaling up the licensedtechnologyandisplanningtobuildapilotscalecellulosicethanolfacilityinToledo,Ohio.
Mithridion, Inc. merged with the UT spin-off CognitivePharmaceuticals to develop drugs for neurologicalandpsychiatricdiseases.Thecompanyhasraised$7.4milliontodateinequityfundingandrecentlyannouncedthe results of its Phase I pharmacokinetic and clinicalstudyofMCD-386,itsleaddrugcandidateforAlzheimer’sdisease. The study produced encouraging results andMithridion is continuing todevelop thedrug for furtherPhaseIstudies.
Xunlight Corporation, a University of Toledo technologyspin-off,develops,manufactures,andmarketsphotovoltaicmodulesthatconvertsunlightintoelectricity.Thecompanyhascompletedinstallingitsfirstfull-scaleproductionline,andmadeitsfirstproductiondeliverytoTheUniversityofToledo. Xunlight recently received the Red Herring 100NorthAmericaAward,honoringthemostpromisingprivatetechnology companies, and the AlwaysOn GoingGreenEast 50 Award, honoring the top private companies incleantechpursuingextraordinaryinnovations.
Start-up ActivityInventors
TheFacultyatTheUniversityofToledohascontinuedtoembracetheUniversity’smissiontoimprovethehumancondition.Asaresult,ourofficesawa59percentincreaseinthenumberofinventiondisclosuressubmitted,whichresultedinadditionallicenses,start-upcompanies,andrevenues.
Medical 47%
Pharmacy1%
Arts & Sciences13%
Engineering 37%
Education1%
Business1%
Industry Sponsored Research, Material Transfer, and Confidentiality Agreements
108
145155
177
139
175
203
0
50
100
150
200
250
FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009
Invention Disclosures
24
34 35 3833
54
91
0
10
20
30
40
50
60
70
80
90
100
FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY2009
Licensing Revenue
$150,434
$337,423
$901,114
$524,575
$865,018$939,307
$1,004,000
$0$200,000
$400,000
$600,000
$800,000
$1,000,000
$1,200,000
FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009
$1,200,000
$1,000,000
$800,000
$600,000
$400,000
$200,000
$0
Deals (Licenses and Options)
5
8
12
7
19
12
22
-
5
10
15
20
25
FY 2003 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008 FY 2009
T E C H N O L O G Y T R A N S F E R
ADVANCING INNOVATION AND ENTREPRENEURSHIP
U T I N N O VAT I O N E N T E R P R I S E S
A N N U A L R E P O RT O N T E C H N O L O G Y T R A N S F E RFiscal Year 2009
Martin Abraham• Anovelsulfur-tolerantcatalystforsteamreformingofdiesel
andjetfuel
Malabala Adiga• Methodofplatingelectrocatalystforhydrogengeneration
Jared Anderson, Fei Zhao, Yunjing Meng, Zhao Qi Chao• Polymericionicliquidsasabsorbentcoatingsinsolidphase
microextraction
Ragheb Assaly, Joseph Shapiro, John Dignam• UseofPEG-Albuminasaplatformfordeliveryofantioxidant
andothermedications
Abdul-Majeed Azad• Carbondioxideandwater-basedfuelcells• HighTemperatureSulfurSorbents(ZSeries)• Carbondioxideandwater-basedfuelcells
Abdul-Majeed Azad, Desikan Sundararajan• Exhaustgaspurificationcatalysts• Acetylenegassensor
Michael Bisesi, Christopher Bork, Paul Rega • Cot-AID(AssistiveIntegratedDevices)(11separatedevicesdisclosed)
Ashok Biyani• Modifiedpediclescrewtipforone-steppercutaneousinsertion• Unidirectionalrotarypediclescrewforcorrectionofspinaldeformity
ingrowingchildren• Directionalsofttissuedilatorsanddockingpinwithintegratedlight
sourceforoptimizationofretractorplacementinminimallyinvasivespinesurgery
• Derotationpediclescrewdesignforsurgicalcorrectionofspinaldeformity
• Fixedandpreloadcompressioncervicalplateswithandwithoutintegratedlockingmechanism
• Posteriorfixationdeviceforpercutaneousstabilizationofthoracolumbarburstfractures
• Expandablecorpectomycageconcept
Ashok Biyani, Philip Nowicki• Femoralneckwasherfixationsystem
Ashok Biyani, Brian Blessinger• Anintegrateddeviceforstorageanddeliveryofbonegraftor
implantablematerial
Ashok Biyani, Gary Durivage• AdjustableHeightPedicleScrew
Christopher Bork• Anergonomichandleforrollingluggage
Thomas Cable, John Setlock• Reformerdesignusingsymmetrical,oxygenconductivemembranes
Brent Cameron, Scott Pappada• Aneuralnetworkbasedapproachforphysiologicalglycemic
forecasting
George Cicila, Soon Jin Lee, Justin Ways• Congenicratstrains(6separatestrainsdisclosed)
Maria Coleman, Hamidreza Hakimelahi, Javed Mapkar• Functionalnanocompositenetworkforreverseselectivemembranes
Alvin Compaan• RapidthermalactivationofflexibleCdTecellsandmodules• Methodtoimproveadhesionofthin-filmsolarcellcoatingsto
polymerfilm• MethodtomakeflexibleCdTemodulesonpolymercastonstainless
steelwebforroll-to-rollmanufacturing
Christopher Cooper• Vascularqualityassurance
Xunming Deng, Qi Hua Fan, Shiban Zhang• PulsedDCreactivesputteringdepositionofzincoxidethinfilmsfrom
zincmetaltarget
Michael Dennis, Dean Walton• ScatterreductioninEPIDradiography
John Dismukes, Lawrence Miller, John Bers• ARImethodologyandscorecardtoolforacceleratingbreakthrough
innovations
Mohammad Elahinia, James Maloney, Majid Tabesh, Richard Yeasting• Bio-inspiredshapememoryalloyesophaguspositioner
Mohammad Elahinia, Vijay Goel, Majid Tabesh• Bio-inspiredshapememoryalloypediclescrewtocompensateforbone
degradationinosteoporosispatients
Mohammad Elahinia, The Nguyen• Mixed-modesemiactivemagnetorheologicalmount
Qi Hua Fan, Xianbo Liao, Xunming Deng, Xianbi Xiang• Highefficiencythinfilmsolarcellsmadewithgradedlightabsorber
materials
Vijay Goel, Hossein Elgafy, Ahmad Faizan• Cervicalspineposteriordynamicsysteminconjunctionwithanartificial
disctotreatthewhiplashinjurypatients
Vijay Goel, Aaron Matyas• Anchoringpediclescrew• Minimallyinvasivecollapsiblecage
Miles Hacker• Usinginactiveanti-cancerdrugstotreatcysticfibrosis
Marthe Howard• Innovativenewtreatmentstrategyforglioma
Dragan Isailovic• Florophore-assistedlaserdesorptionionizationmassspectrometry
(FALDI-MS)
Samer Khouri, Sonia Najjar• Novelmodelofthemetabolicsyndromewithassociatedspontaneous
atherosclerosis
Dong-Shik Kim, Maria Coleman• SuspensiontechniqueforGochangyellowclay
Tony Koesters, Brian Kanney, Ryan Kremer, Allan Gindy, Faisal Bukhari• BurnableShreddedPaperLogs
Yun-Ming Lin• Reactionrateaccelerationviaasymmetricbifunctionalcatalysis
Terri Lombardo• Novelrenewableelectricenergy
Ioan Marinescu• Penetratingcompoundswithvariableproperties
Mark Mason• Newtrianionicligandsforconstrainedgeometrycatalysts
Udayan Nadkeolyar• Pilotfreehighspeedsurfacetransportationcapsule
Philip Nowicki, Ashok Biyani, Martin Skie• Antibioticclusteredpercutaneouspincoversystem
Thomas Papadimos• Thebeneficialeffectsofinhalednitricoxideinpatientswithsevere
traumaticbraininjurycomplicatedbyacuterespiratorydistresssyndrome
Invention DisclosuresCatherine Powell• MARKtheSpot–Answersonthespot• Backlace
Carmen Quatman, Andrew Maszaros, Catherine Quatman• Shoulderbracefordecreasedpassiverestraints
Martin Rice• Learningtotelltimeusingknowledgeofresults
Edwin Sanchez, Garrett Heinrich, Terry Hinds• Discoveryofglucocorticoidreceptorbetainmice
Rebecca Schneider• ALearningCommunityofTeachers(ALCOT)
Steven Selman, Hinman Channing• Applicationsofcobratoxinandderivatives
Lirim Shemshedini, Changmeng Cai, Shao-Yong Chen, Chen-Lin Hsieh• Solubleguanylylcyclasealpha1(sGCalpha1)asanoveldiagnostic
markerofandthereapeutictargetforprostatecancer• V94Cells:Anovelandrogen-independentLNCaPcellline
Krishna Shenai, Nikhil Gudi, Dhakshina Thavamani• Anovelhybridthermoelectricenergyconverter(TEC)andphotovoltaic
(PV)system
Krishna Shenai, Nikhil Gudi, Dhakshina Thavamani, Premchand Boyapati, Prashanth Reddy• HybridsmartmodularDCpowersystem
Krishna Shenai, Nikhil Gudi• Wirelesssmartmovableantenna• Remotelycontrollablesmartwidebandwirelessantenna• Smartwirelesslytunablecommunicationsystempowerfrom
renewableenergysources
Krishna Shenai, Ashok Biyani, Vijay Goel, Vijay Devabhaktuni, Bradford Lilly• Anovelprocedureandapparatusforperforminghighly
accuratesurgery
Krishna Shenai, Premchand Boyapati, Dhakshina Thavamani, Jessica Jordan• Novelwirelesssensorcommunicationusingsoundwaves
Krishna Shenai, Premchand Boyapati• Multi-functionlow-powerwirelessairsensor• Smartremotesensingandwirelessinformationmanagement• Anovelwirelesssensorsystemforstructuralhealthmonitoring
Krishna Shenai, Bradford Lilly, Premchand Boyapati• Automatedswimmingpoolmanagementsystem• Amethodforpreciseintelligentsoilchemicaldistribution
Thomas Stuart• Amodularizedsystemwithrelaysformanagingseriesconnected
batterycells
Zi-Jian Xie Jiang Tian• Na/K-ATPaseexpressionasanindicatorfortreatmentofcancer
Zi-Jian Xie, Joseph Shapiro, Zhichuan Li• Na/K-ATPase-derivedpeptidesasantagonistofCTSandas
therapeuticagentsforcancer
Daniel Kory, Ph.D., MBAAssociate Vice President for Technology TransferPhone: 419.383.6924Email: daniel.kory@utoledo.edu
Stephen Snider, J.D.Director, Technology Licensing & Contracts Phone: 419.383.6963
Email: stephen.snider@utoledo.edu
Mark Fox, J.D., MSPatent Technology AssociatePhone: 419.383.6907Email: mark.fox@utoledo.edu
Samuel Giles, MBAPatent Licensing AssociatePhone: 419.383.6965Email: samuel.giles3@utoledo.edu
Sandra RhoadesIP AdministratorPhone: 419.383.6923Email: sandy.rhoades@utoledo.edu
Contacts
INNOVATIONENTERPRISES
INNOVATIONENTERPRISES
W W W. U T O L E D O . E D U / R E S E A R C H / T E C H T R A N S F E R
IR 1
92 1
009
250
In2009,UTInnovationEnterpriseswascreatedtodiversifyandtransformtheregionaleconomybyfacilitatingthedevelopmentandattractionofscienceandtechnology-basedorganizations.Bybringingtogetherresearchdevelopment,technologytransfer,incubation,workforcedevelopmentandtheScienceandTechnologyCorridor,theUniversitybelievesitwillbeabletoenhancetheglobalcompetitivenessofNWOhio.
T E C H N O L O G Y T R A N S F E R
ADVANCING INNOVATION AND ENTREPRENEURSHIP
U T I N N O VAT I O N E N T E R P R I S E S
A N N U A L R E P O RT O N T E C H N O L O G Y T R A N S F E RFiscal Year 2009
Martin Abraham• Anovelsulfur-tolerantcatalystforsteamreformingofdiesel
andjetfuel
Malabala Adiga• Methodofplatingelectrocatalystforhydrogengeneration
Jared Anderson, Fei Zhao, Yunjing Meng, Zhao Qi Chao• Polymericionicliquidsasabsorbentcoatingsinsolidphase
microextraction
Ragheb Assaly, Joseph Shapiro, John Dignam• UseofPEG-Albuminasaplatformfordeliveryofantioxidant
andothermedications
Abdul-Majeed Azad• Carbondioxideandwater-basedfuelcells• HighTemperatureSulfurSorbents(ZSeries)• Carbondioxideandwater-basedfuelcells
Abdul-Majeed Azad, Desikan Sundararajan• Exhaustgaspurificationcatalysts• Acetylenegassensor
Michael Bisesi, Christopher Bork, Paul Rega • Cot-AID(AssistiveIntegratedDevices)(11separatedevicesdisclosed)
Ashok Biyani• Modifiedpediclescrewtipforone-steppercutaneousinsertion• Unidirectionalrotarypediclescrewforcorrectionofspinaldeformity
ingrowingchildren• Directionalsofttissuedilatorsanddockingpinwithintegratedlight
sourceforoptimizationofretractorplacementinminimallyinvasivespinesurgery
• Derotationpediclescrewdesignforsurgicalcorrectionofspinaldeformity
• Fixedandpreloadcompressioncervicalplateswithandwithoutintegratedlockingmechanism
• Posteriorfixationdeviceforpercutaneousstabilizationofthoracolumbarburstfractures
• Expandablecorpectomycageconcept
Ashok Biyani, Philip Nowicki• Femoralneckwasherfixationsystem
Ashok Biyani, Brian Blessinger• Anintegrateddeviceforstorageanddeliveryofbonegraftor
implantablematerial
Ashok Biyani, Gary Durivage• AdjustableHeightPedicleScrew
Christopher Bork• Anergonomichandleforrollingluggage
Thomas Cable, John Setlock• Reformerdesignusingsymmetrical,oxygenconductivemembranes
Brent Cameron, Scott Pappada• Aneuralnetworkbasedapproachforphysiologicalglycemic
forecasting
George Cicila, Soon Jin Lee, Justin Ways• Congenicratstrains(6separatestrainsdisclosed)
Maria Coleman, Hamidreza Hakimelahi, Javed Mapkar• Functionalnanocompositenetworkforreverseselectivemembranes
Alvin Compaan• RapidthermalactivationofflexibleCdTecellsandmodules• Methodtoimproveadhesionofthin-filmsolarcellcoatingsto
polymerfilm• MethodtomakeflexibleCdTemodulesonpolymercastonstainless
steelwebforroll-to-rollmanufacturing
Christopher Cooper• Vascularqualityassurance
Xunming Deng, Qi Hua Fan, Shiban Zhang• PulsedDCreactivesputteringdepositionofzincoxidethinfilmsfrom
zincmetaltarget
Michael Dennis, Dean Walton• ScatterreductioninEPIDradiography
John Dismukes, Lawrence Miller, John Bers• ARImethodologyandscorecardtoolforacceleratingbreakthrough
innovations
Mohammad Elahinia, James Maloney, Majid Tabesh, Richard Yeasting• Bio-inspiredshapememoryalloyesophaguspositioner
Mohammad Elahinia, Vijay Goel, Majid Tabesh• Bio-inspiredshapememoryalloypediclescrewtocompensateforbone
degradationinosteoporosispatients
Mohammad Elahinia, The Nguyen• Mixed-modesemiactivemagnetorheologicalmount
Qi Hua Fan, Xianbo Liao, Xunming Deng, Xianbi Xiang• Highefficiencythinfilmsolarcellsmadewithgradedlightabsorber
materials
Vijay Goel, Hossein Elgafy, Ahmad Faizan• Cervicalspineposteriordynamicsysteminconjunctionwithanartificial
disctotreatthewhiplashinjurypatients
Vijay Goel, Aaron Matyas• Anchoringpediclescrew• Minimallyinvasivecollapsiblecage
Miles Hacker• Usinginactiveanti-cancerdrugstotreatcysticfibrosis
Marthe Howard• Innovativenewtreatmentstrategyforglioma
Dragan Isailovic• Florophore-assistedlaserdesorptionionizationmassspectrometry
(FALDI-MS)
Samer Khouri, Sonia Najjar• Novelmodelofthemetabolicsyndromewithassociatedspontaneous
atherosclerosis
Dong-Shik Kim, Maria Coleman• SuspensiontechniqueforGochangyellowclay
Tony Koesters, Brian Kanney, Ryan Kremer, Allan Gindy, Faisal Bukhari• BurnableShreddedPaperLogs
Yun-Ming Lin• Reactionrateaccelerationviaasymmetricbifunctionalcatalysis
Terri Lombardo• Novelrenewableelectricenergy
Ioan Marinescu• Penetratingcompoundswithvariableproperties
Mark Mason• Newtrianionicligandsforconstrainedgeometrycatalysts
Udayan Nadkeolyar• Pilotfreehighspeedsurfacetransportationcapsule
Philip Nowicki, Ashok Biyani, Martin Skie• Antibioticclusteredpercutaneouspincoversystem
Thomas Papadimos• Thebeneficialeffectsofinhalednitricoxideinpatientswithsevere
traumaticbraininjurycomplicatedbyacuterespiratorydistresssyndrome
Invention DisclosuresCatherine Powell• MARKtheSpot–Answersonthespot• Backlace
Carmen Quatman, Andrew Maszaros, Catherine Quatman• Shoulderbracefordecreasedpassiverestraints
Martin Rice• Learningtotelltimeusingknowledgeofresults
Edwin Sanchez, Garrett Heinrich, Terry Hinds• Discoveryofglucocorticoidreceptorbetainmice
Rebecca Schneider• ALearningCommunityofTeachers(ALCOT)
Steven Selman, Hinman Channing• Applicationsofcobratoxinandderivatives
Lirim Shemshedini, Changmeng Cai, Shao-Yong Chen, Chen-Lin Hsieh• Solubleguanylylcyclasealpha1(sGCalpha1)asanoveldiagnostic
markerofandthereapeutictargetforprostatecancer• V94Cells:Anovelandrogen-independentLNCaPcellline
Krishna Shenai, Nikhil Gudi, Dhakshina Thavamani• Anovelhybridthermoelectricenergyconverter(TEC)andphotovoltaic
(PV)system
Krishna Shenai, Nikhil Gudi, Dhakshina Thavamani, Premchand Boyapati, Prashanth Reddy• HybridsmartmodularDCpowersystem
Krishna Shenai, Nikhil Gudi• Wirelesssmartmovableantenna• Remotelycontrollablesmartwidebandwirelessantenna• Smartwirelesslytunablecommunicationsystempowerfrom
renewableenergysources
Krishna Shenai, Ashok Biyani, Vijay Goel, Vijay Devabhaktuni, Bradford Lilly• Anovelprocedureandapparatusforperforminghighly
accuratesurgery
Krishna Shenai, Premchand Boyapati, Dhakshina Thavamani, Jessica Jordan• Novelwirelesssensorcommunicationusingsoundwaves
Krishna Shenai, Premchand Boyapati• Multi-functionlow-powerwirelessairsensor• Smartremotesensingandwirelessinformationmanagement• Anovelwirelesssensorsystemforstructuralhealthmonitoring
Krishna Shenai, Bradford Lilly, Premchand Boyapati• Automatedswimmingpoolmanagementsystem• Amethodforpreciseintelligentsoilchemicaldistribution
Thomas Stuart• Amodularizedsystemwithrelaysformanagingseriesconnected
batterycells
Zi-Jian Xie Jiang Tian• Na/K-ATPaseexpressionasanindicatorfortreatmentofcancer
Zi-Jian Xie, Joseph Shapiro, Zhichuan Li• Na/K-ATPase-derivedpeptidesasantagonistofCTSandas
therapeuticagentsforcancer
Daniel Kory, Ph.D., MBAAssociate Vice President for Technology TransferPhone: 419.383.6924Email: daniel.kory@utoledo.edu
Stephen Snider, J.D.Director, Technology Licensing & Contracts Phone: 419.383.6963
Email: stephen.snider@utoledo.edu
Mark Fox, J.D., MSPatent Technology AssociatePhone: 419.383.6907Email: mark.fox@utoledo.edu
Samuel Giles, MBAPatent Licensing AssociatePhone: 419.383.6965Email: samuel.giles3@utoledo.edu
Sandra RhoadesIP AdministratorPhone: 419.383.6923Email: sandy.rhoades@utoledo.edu
Contacts
INNOVATIONENTERPRISES
INNOVATIONENTERPRISES
W W W. U T O L E D O . E D U / R E S E A R C H / T E C H T R A N S F E R
IR 1
92 1
009
250
In2009,UTInnovationEnterpriseswascreatedtodiversifyandtransformtheregionaleconomybyfacilitatingthedevelopmentandattractionofscienceandtechnology-basedorganizations.Bybringingtogetherresearchdevelopment,technologytransfer,incubation,workforcedevelopmentandtheScienceandTechnologyCorridor,theUniversitybelievesitwillbeabletoenhancetheglobalcompetitivenessofNWOhio.
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