abilitazione a professore di i fascia 06/d6 nella tornata ... · curriculum vitae general...
Post on 28-Jun-2020
1 Views
Preview:
TRANSCRIPT
CURRICULUM VITAE GENERAL INFORMATION
Name Antonio Uccelli Coniugal state Married with Messmer Michele (USA); One child (Cesar) Home address Via Albaro 9/10 D 16145 – Genova Phone: 010/312049 E-mail: auccelli@me.com Work address Università degli Studi di Genova Dipartimento di Neuroscienze, Oftalmologia e Genetica Largo Paolo Daneo, 3, 16132 Genova, Italia Phone: (39) 10/3537040/28/48 Fax: (39) 10/3538631 E-mail: auccelli@neurologia.unige.it
Date of Birth November 18,1964 Genova, Italia Position: Associate Professor of Neurology Head MS Clinic and Neuroimmunology Unit Department of Neurology, Rehabilitation, Ophthalmology,
Genetics, Maternal and Child Health (DINOGMI) University of Genoa Largo P. Daneo, 3 16132 - Genoa Phone direct: +39 010 3537028 Phone Assistant: +39 010 3537048 Phone MS Clinic: +39 010 35338712 email1: auccelli@neurologia.unige.it Education
1983 Maturita’: Liceo Classico “A.Doria” Genova 1989 M.D. Degree Magna Cum Laude, University of Genoa 1989 Italian Board of Medicine: completed with honors 1993 Italian Board of Neurology: completed with honors
Postdoctoral training Internships and Residency
1984-1986 Intern in Anatomy with Prof. D. Zaccheo, Istituto di Anatomia, University of Genoa
1986-1987 Intern in Virology with Dr. O. Varnier, Istituto di Microbiologia, University of Genoa
1987-1989 Intern in Neurology with Prof. E. Favale, Clinica Neurologica, University of Genoa
1989-1993 Resident in Neurology, Clinica Neurologica, University of Genoa
2012 abilitazione a Professore di I Fascia 06/D6 nella tornata 2012 (valida dal
3/02/2014 al 3/02/2020).
2
Research Fellowship 1991-1992 Research fellow with Dr. F. Manca, Istituto di Immunologia, University of
Genoa, Italy 1992 Visiting Scientist at the Department of Neurological and Psychiatric,
University of Florence, Italy 1992-1994 Visiting Scientist with Prof. S.L. Hauser, Department of Neurology,
University of California, San Francisco Positions and Employment
1993-2011 Dirigente Medico di I livello (Assistant Professor Level), Department of Neurosciences, Ophthalmology and Genetics-University of Genoa.
1995- Head of the Neuroimmunology Lab of Department of Neurosciences, Ophthalmology and Genetics-University of Genoa.
2008-2015 Director of the Neuroimmunobiology Laboratory of the Advanced Biotechnology Center (CBA) of Genoa
2006- Head Multiple Sclerosis Clinic Department-University of Genoa 2011- Associate Professor of Neurology, University of Genoa 2012-2015 Coordinator of the Residency School of Neurosurgery, University of
Genoa 2012 - President of Italian Association of Neuroimmunology (AINI) 2014 - Director of Centre of Excellence for Biomedical Research (CEBR)
Teaching experience:
1998-2013 Professor of “Elements of Neuropathology” in the Residency Program of Physical Rehabilitation at the University of Genoa
1999- Professor of “Elements of Neuroimmunology” in the Residency Program of Neurology at the University of Genoa
2006- Professor of Neurology in the PhD program on Neurosciences 2009 - Professor of Neuropathology in Biotechnology degree course at the
University of Genoa 2014 - Professor of Neurology in the Residency Program of Pediatrich
Neuropsychiatry 2015 - Coordinator of Curriculum “Neuroscienze cliniche e sperimentali” – in the
PhD program on Neurosciences
Professional Awards
2001 Rita Levi Montalcini Award. Italian Multiple Sclerosis Researcher of the Year
2009 Melvin Jones Fellow Award (for dedicated humanitarian services Lions Clubs International Foundation)
2013 Royan International Research Award - an annual prize awarded to the excellences in Reproductive Biomedicine, Reproductive Health, and Stem Cell Biology and Technology.
Scientific collaborations:
- Vito Pistoia (Ospedale Pediatrico Bambin Gesù, Roma).
- Gianni Bonanno and Ernesto Fedele (DIFAR -Università degli Studi di Genova)
- Fabio Benfenati (DIMES - Università degli Studi di Genova)
- Laura Vergani (Istituto di Fisiologia - Università degli Studi di Genova)
- Marco Bacigaluppi, Roberto Furlan, Gianvito Martino (IRCCS Ospedale San Raffaele,
3
Milano)
- Guido Ferlazzo (Dipartimento di Patologia Umana dell'adulto e dell'età evolutiva
Gaetano Barresi, Università di Messina)
- Federica Sallusto e Antonio Lanzavecchia (Istituto di Ricerca in Biomedicina,
Bellinzona, Svizzera)
- Jorge Oksenberg e Sergio Baranzini (Department of Neurology,
University of California at San Francisco (UCSF))
- Amit Bar-Or (Neurological Institute, McGill University, Montreal, Canada)
- Pablo Villoslada (Hospital Clinic-Institut d'Investigacions Biomèdiques, Barcelona,
Spain)
- Mark Freedman (University of Ottawa, Ottawa Hospital Research Institute, Canada)
- Gavin Giovannoni (Queen Mary University of London – UK)
- Lorenzo Moretta (Ospedale Pediatrico Bambin Gesù, Roma)
- Alessandro Moretta (DIMES - Università di Genova)
- Gianluigi Forloni e Claudia Balducci (Istituto di Ricerche farmacologiche Mario Negri,
Milano)
- Giuseppe Matarese (Dipartimento di Medicina molecolare e Biotecnologie mediche
Universita’ Federico II, Napoli)
- Diego Centonze (IRCCS NEUROMED – Istituto Neurologico Mediterraneo, Pozzilli
(IS))
- Marco Salvetti (Centre for Experimental Neurological Therapies (CENTERS)
Universita’ La Sapienza, Roma)
- Claudia Verderio (CNR Institute of Neuroscience, Milano)
- Jens Thomas Wuerfel (Medical Image Analysis Center (MIAC), Basilea, Svizzera)
- Paul Friedemann (Charitè Università Smedizin Berlin, Germany)
- Hanne Flinstad Harbo (UiO Institutt for klinisk medisin, Oslo)
- Paolo Muraro e David Miller (Imperial College, London, UK)
- Daniela Virgintino (Dipartimento di Anatomia Umana e Istologia, Università di Bari)
- Roland Liblau and Michel Clanet (Toulouse University Medical School, France)
Membership in Professional and Scientific Committee and Societies International
International Mesenchymal Stem Cells Transplantation Study Group (IMSCTSG) (2012 - ) Board International Society of Neuroimmunology (ISNI) The Henry Kunkel Society Board European School of Neuroimmunology (ESNI) ECTRIMS Council (2013 - ) National Italian Society of Neuroimmunology (2003-2009-Secretary of the Executive Board, 2012- President) (SIN) Secretary of the Scientific Board of the Residential Course of Neuroimmunology - CRNI Program
4
Italian Society of Immunology and Clinic Immunology and Allergology (SIICA) Italian Society for Multiple Sclerosis (Secretary of the Research Committee 2003-2005) (FISM) Italian Society of Neurology Italian Society of Immunology Associazione Italiana di Neuroimmunologia (AINI) (President 2012 - ) Stem Cell Research Italy Scientific Committee Regione Liguria (2011 - ) Scientific Committee of Istituto G. Gaslini - Istituto Pediatrico di Ricovero e Cura a Carattere Scientifico (2014 – 2015) Medical Education Committee dell’IRCCS AUO San Martino IST – Genova (2015 - ) Committee for the Research Quality of University of Genoa (2014 - ) Ad hoc reviewer for Scientific Association
AFM Telethon (France) Australian MS Society, ELA Association Européenne contre les Leucodystrophies (ELA) (France) Hasselt University (Belgium) Weissman Institute (Israel) ARSEP (Association pour la Recherche sur la Sclerose en Plaque (France) INSERM (France) Italian MS Society Italian National Council of Research (CNR) Italian Ministry of Health Ministero Italiano dell’Istruzione, dell’Università e della Ricerca(MIUR) National MS Society (USA) New Zeeland Neuroscience Foundation Swiss National Science Foundation The National Kidney Research Fund (UK) UK MS Society (UK) Wellcome Trust (UK) Science Foundation of Ireland Swiss MS Society Scientific Journals
Acta Neuropathologica Archives of Neurology Annals of Neurology Blood Bone Marrow Transplantation Brain Brain Research Clinical and Developmental Immunology Cytotherapy European Journal of Immunology European Journal of Neurosciences Experimental Neurology Glia Hematologica Immunogenetics Immunology Letters International Immunopharmacology International Journal of Neurosciences Journal of Alzheimer’s diseases Journal of Cellular and Molecular Medicine Journal of Molecular Neurosciences Journal of Immunology
5
Journal of Neurochemistry Journal of Neuroimmune Pharmacology Journal of Neuroimmunology Journal of Neurology Journal of Neurological Sciences Journal of Neuroscience Research Journal of Neuroimmuno-Pharmacology Lancet Lancet Neurology Multiple Sclerosis Journal Multiple Sclerosis International journal Nature Biotechnology Nature Communications Nature Reviews Immunology Neurobiology of Diseases Neurology Neurogical Sciences Pharmacological Research Physiological Genomics Plos One Proceedings of the National Academy of Sciences USA (PNAS) Pediatric Research Regenerative Medicine (Member of the Editorial Board) Rheumatology Stem Cells Stem Cells and Development Stem Cells Research Advisory Board Membership (previous and present):
CARIVERONA, Allergan, Androclus Therapeutics, Merck-Serono, Biogen, Bayer, Pharma,
Novartis, Genentech, Roche, Juvenile Diabetes Research Foundation, TEVA, Regione Liguria,
WebMD Global LLC , Prova Education, TOPEC Global
Membership in Editorial Board:
Journal of Neuroimmune Pharmacology
Research Activities • Clinical Neuroimmunology and multiple sclerosis • Immunology of Multiple Sclerosis and experimental autoimmune encephalomyelitis • Adult Stem cells • Autoimmunity in neurology Teaching and Mentoring
Predoctoral Students Supervised or Mentored
Name Program or School Role Current Position
Benedetta Parodi Biotechnology Mentor Post Doc
Ilaria Gandoglia Medicine Co-Mentor Resident
Eric Armentani Biotechnology Mentor PhD Student
Giovanni Novi Medicine Co-Mentor Resident
Kledi Hametaj Molecular Biology Mentor Student
Maria Cellerino Medicine Mentor Resident
6
Ambra Bisso Biotechnology Mentor N.A.
Queliane de Oliveira Pharmacology Co-Mentor N.A
Luca Tagliafico Medicine Mentor Student
Tommaso Croese Medicine Co-Mentor PhD student
Alberto Bragoni Medicine Mentor Student
Monica Truffelli Medicine Mentor Resident
Paolo Enrico Medicine Mentor Student
Chiara Marini Neurobiology Mentor PhD Student
Giacomo Marro Medicine Co-Mentor Student
Alessandra Murialdo Medicine Mentor MD
Arinna Bertoni Biotechnology Mentor PhD Student
Venturi Consuelo Supervised Technician
Federico Ivaldi Supervised Technician
Domenico Cerminara Medicine Mentor
Davide Guerra Biotechnology Mentor Student
Valentina Ghio Biotechnology Mentor Student
Gianluca Como Mentor Student
Marina Romani Mentor Student
Jasmine Ortolan Mentor Student
Sara Capriccioli Biotechnology Mentor Student
Postdoctoral Fellows Supervised or Mentored
Name Fellow Role Current Position
Benedetta Parodi PhD Mentor Post Doc - University of Genoa
FedericaBenvenuto PhD Mentor Post Doc - University of Genoa
Tiziana Vigo PhD Mentor Post Doc - University of Genoa
Simona Casazza PhD Mentor Post Doc
Laura Lovato PhD Mentor Post Doc - IIT
Debora Giunti PhD Mentor Faculty - University of Genoa
Laura Serpero PhD Mentor Post Doc
Emanuela Zappia PhD Mentor Post Doc
Alice Laroni PhD Mentor PhD Student
Sabrina Chiesa PhD Mentor Post Doc
Gerdoni Ezio PhD Mentor Post Doc
Marchese Monica PhD Mentor Post Doc
Claudio Solaro Resident Mentor MD
Invited Presentations-International (last 10 years) 2007:
- University of Cambridge; UK (seminar)
- Fundacion Areces; Madrid; Spagna (speaker)
- Cellaid symposium; Firneze, Italia (invited speaker)
- European School of NeuroImmunology (ESNI), Oxford UK (speaker)
2008:
- 2nd Gaslini Advanced course in Basic and applied Immunology; Gaslini-Genova (speaker)
- European Emathology Association (EHA); Francia (speaker)
- Congresso Lega Italiana contro l’Epilessia (L.I.C.E.); Venezia (speaker)
- MS Experten-Workshop; Monaco; Germania (speaker)
7
- Corso Post-Universitario in Immunologia; Verona (speaker)
- University of Hamburg; Amburgo; Germania (seminar)
- Tissue Engineering and Regenerative Medicine International Society; Porto; Portogallo
(speaker)
2009:
- Georg-August University; Goettingen; Germania (seminar)
- Research Challenges in Multiple Sclerosis Rihabilitation (RIMS); Genova (speaker)
- Swiss Multiple Sclerosis Society; Berna; Svizzera (speaker)
- Swiss Society of Allergology and Immulogy Conference; Geneva; Svizzera(speaker)
- European Biophysical Societies Association; Genova (speaker)
- Translation Research in Paediatric Rheumatology (TRiPR); Gaslini-Genova (speaker)
- Cemcat - Val d’Hembron University Hospital; Barcellona; Spagna (seminar)
- Institut Fédératif de Recherche Bio-Médicale de Toulouse; Tolosa; Francia (seminar)
- International Society for Cellular Therapy (ISCT); Bethesda-Usa (speaker)
- 1st International Global COE Symposium; Sendai-Japan (speaker)
2010:
- Keystone Symposia; Taos-New-Mexico; USA (speaker)
- 5th Helsinki Biomedical Graduate School Student Council Symposium; Helsinki; Finlandia
(speaker)
- Annual Meeting of the Consortium of Multiple Sclerosis Centers; San Antonio; Texas; USA
(speaker)
- Texas A&M Institute; Texas –USA- (seminar)
- University Department of Rheumatology; Basel; Svizzera (seminar)
- 1st Meeting Stem Cell Reserarch Italy; Pontignano (speaker)
- 14th International Congress of Immunology; Kobe-Japan (speaker)
- Associazione Italiana Neuroimmunologia (AINI); Stresa (speaker)
- 26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis
(ECTRIMS); Gothenburg; Svezia (speaker)
- International Society for Neurovirology (ISNV); Milano (speaker)
- 1st European Conference on MSCs and Regeneration; Toulouse; Francia (speaker)
- “Neuroinflammatory diseases-from pathogenesis to therapy”; University of Muenster
Germania (speaker)
- 10th International Congress of Neuroimmunology (ISNI) Barcellona; Spagna (speaker)
- Vth UCL Review Course on Systemic Rheumatic Diseases – Brussels; Belgio (speaker)
- Multiple Sclerosis Immunological conference; University of Nottingham; UK (seminar)
2011:
- “Spring 2011 External Speaker Programme" University College London; Londra; UK
(seminar)
- “The enigma of inflammation in ALS: What can be learned from other neurological
diseases?” - Weizmann Institute, Rehovot, Israel (seminar)
- Event “Best Practice & Research Clinical Haematology “, London; UK (speaker)
- Symposium of the Bavarian Research Network, Monaco; Germania (speaker)
- “Multiple sclerosis symposium” – American University of Beirut Medical Center, Libano
(speaker)
- Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting, Montreal (speaker)
- 11th ESNI Course - European School of Neuroimmunology, Glasgow; UK (speaker)
- 35° Congresso Nazionale Società Italiana di Farmacologia (SIF) - Bologna, (speaker)
- Istituto di Ricerca in Biomedicina (IRB) Lecture: Mesenchymal stem cells: a new cell therapy
for the treatment of autoimmunity, Bellinzona; Svizzera. (seminar)
- XXIX Conferenza Nazionale Di Citometria, Società Italiana di Citometria (SIC), Salerno,
(speaker)
- Convegno uniStem 11ªGiornata di Studio sulle Cellule Staminali - Unistem, Milano (speaker)
8
- Insubria Autumn School of Neuroimmunopharmacology, University of Insubria, Varese –
Italy (speaker)
- 2011 Henry Kunkel Society meeting, Washington, DC (speaker)
2012
- “Translational & clinical issues in pediatric rheumatology” – Pediatric Research European
Society Course, Genova – Italia (speaker)
- istituto Mario Negri Milano – Italia (seminar).
- Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano (Torino), Italy (seminar)
- Ospedale Cervello Palermo - Italia (Seminar)
- International Summer Course. Murcia University 2012, Aguilas. Murcia. Spain (Speaker)
- Istituto Italiano di Tecnologia Genova (Seminar)
- European Congress of Immunology, Glasgow, UK (Speaker)
- 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis
Lyon, France (speaker)
- Mesenchymal Stem Cells in Solid Organ Transplantation (MISOT) Barcelona Spain (speaker)
- 11th International Society of NeuroImmunology (ISNI) Washington USA (speaker)
2013
- Congress “World Immune Regulation Meeting (WIRM)-VI” Davos - Switzerland” (speaker)
- Karolinska Institutet, Stoccolm – Sweden (seminar)
- Workshop on Transplant and Cellular Therapy for Autoimmune Diseases - Milwaukee – USA
(speaker)
- 23rd Meeting of the European Neurological Society – Barcellona – Spagna – (speaker)
- Clinical Trial Design for a Cellular Therapeutic in MS Patients – Orlando – USA (speaker)
- Queen's University Belfast – Belfast – Ireland (seminar)
- Seminar at Ospedale Regionale "Ca' Foncello" – Treviso – Italy (speaker)
- international summer course "CELL THERAPY FROM THE BENCH TO THE BEDSIDE AND
RETURN" - Los Alcázares, Murcia – Spain (speaker)
- 15th International Congress of Immunology – Milano – Italy (speaker)
- Royan Institute – Teheran –Iran (awarded)
- Cell Society International’s 3rd Annual Clinical Meeting – San Diego – USA (speaker)
- University California San Francisco (UCSF) – San Francisco – USA (seminar)
- Cell Society Europe – Marseille – France (speaker)
2014
- Mesenchymal Stem Cells in Solid Organ Transplantation (MISOT) Ranica (BG) - Italy
(speaker)
- EBMT 2014 Congress; Milano - Itay (speaker)
- Controversies in Neurology meeting (CONy); Berlino – Germany (speaker)
- TERMIS EU Chapter Meeting; Genova – Italy (speaker)
- II Annual Multiple Sclerosis Management meeting; Vienna – Austria (speaker)
- international summer course "CELL THERAPY FROM THE BENCH TO THE BEDSIDE AND
RETURN" - Los Alcázares, Murcia – Spain (speaker)
- 9th Congress of the International Society for NeuroImmunoModulation - LIEGE – BELGIO
(speaker)
- Congresso Associazione Italiana Neuroimmunologia (AINI) – Sorrento (NA) – Italy (speaker)
- VIII Brazilian Congress of Stem Cell and I Latin American Symposium of Stem Cell - Foz do
Iguaçu, State of Paraná-Southern Brazil (speaker)
- 13th International Congress Of Neuroimmunology (ISNI) Mainz, Germany (Speaker)
- XLV Congresso Della Societa' Italiana Di Neurologia – SIN, Cagliari, Italy (speaker)
2015
- University of Padua –Italy (Seminar)
- Feinsten Institute – New York – USA (Seminar)
9
- Advanced cellular therapies and regenerative medicine, B-DEBATE CONFERENCE –
Barcelona Spain (speaker)
- X Convegno Nazionale SINDEM – Genova – Italy (Speaker)
- Milano-Bicocca University, Monza, Italy (Speaker)
- 115th ESNI Course - European School of Neuroimmunology, Prague, CZECH REPUBLIC
(Speaker)
- International Joint Israeli-Greek-Italian Neuroimmunology Meeting - Crete, Greece
(Speaker)
- International summer course "CELL THERAPY FROM THE BENCH TO THE BEDSIDE AND
RETURN" Los Alcázares, Murcia – Spain (speaker)
- Iran MS Congress, Sari, Mazandaran, IRAN (speaker)
- International Conference on Cell-Based Therapies for Multiple Sclerosis, Lisboa, Portugal
(speaker)
2016
- Harvard Stem Cell Institute (HSCI)'s, Boston, MA (seminar)
- Controversies in Neurology meeting (CONy), Lisboa, Portugal (speaker)
- 2nd European Academy of Neurology (EAN), Copenaghen, Denmark (speaker)
- Congress of the Spanish Society of Blood Transfusion and Haemotherapy, Bilbao, Spagna
(speaker)
- 13th ISNI International Congress of Neuroimmunology, Jerusalem, Israel (speaker)
- XXVII Congresso nazionale della SINPIA, Alghero, Itlay (speaker)
- XLVII Congresso Della Societa' Italiana Di Neurologia – SIN, Venezia, Italy (speaker)
- 3rd International Congress on Responsible Stem Cells Research from Cells to Cell Products:
Development of New Therapeutic Tools, Padova, Italy (speaker)
- Grandangolo Neurologia – Genova. Italia (speaker)
2017
- IRCCS Neuromed, Pozzilli, Isernia, Italy (seminar)
- Università dell’Aquila, Italy (seminar)
- Cemcat - Val d’Hembron University Hospital; Barcellona; Spagna (seminar)
- IRCCS S. De Bellis, Castellana Grotte (BA) (seminar)
- International Society for Cellular Therapy – London, UK – (speaker)
- Annual Scientific Meeting of European Society for Clinical Investigation (ESCI) – Genoa,
Italy – (speaker)
GRANTS (last 6 years)
2016
� Compagnia di San Paolo, “Studio dell’effetto immunomodulante e neuroriparativo delle
cellule staminali mesenchimali in pazienti con sclerosi multipla” (€137.000,00)
� ERA-NET – Call EraCoSysMed – “Personalizing health care in Multiple Sclerosis using
systems medicine tools – Sys4MS”. (€165.000,00)
� Motor Neuron Disease Association (UK) - “Exosome-shuttled miRNAs as mediators of the
therapeutic effect of mesenchymal stem cells in ALS” Co-PI (200.000£)
2015
� Novartis Italia, “Assessment of the effect of fingolimod on new pathways involved in
neuroprotection” (€101,900,00)
� Italian Foundation For Multiple Sclerosis (FISM), “Targeting terapeutico dell'attività e
dell'espressione di REST allo scopo di ridurre la neurodegenrazione ed i deficit sinaptici
in modelli di EAE cronica” PI (€235.000,00)
10
� Fondazione Cariplo “Aged induced hematopoietic and neurogenic dysfunctions
contribute to the worse outcome” Co-PI (€100.000,00)
� Biogen USA, “Dissection of the role of HCAR2 in the therapeutic features and potential
side effects exerted by dimethylfumarate in multiple sclerosis” (€247.000,00)
� Paul Allen Family Foundation (USA) “Can Mesenchymal Stem Cell Secretome Repair
Alzheimer’s Disease Brains?” Co-PI (€100.000,00)
� Grant for Multiple Sclerosis Innovation (GMSI) Project: “Driving microglia metabolism
toward remyelination and restoration of brain damage in multiple sclerosis”. Co-PI
(€350,000,00)
2014
� Merck Serono Italia, “Effect of Interferon (IFN)-β on Mesenchymal Stem Cells
“(€50.000,00)
2013
� Biogen USA, Sponsored Research Agreement on mechanisms of action of Tecfidera
($89.400,00)
2012
� Fondazione ARSEP finanziamento per il progetto: “A French-Italian collaboration for the
MESEMS (MEsenchymal StEm cells for the therapy of Multiple Sclerosis) trial”
(€175.000,00) Co-PI
� Fondazione CARIGE finanziamento per il progetto: ”Studio clinico sull'uso delle cellule
staminali mesenchimali per la cura della Sclerosi Multipla (studio MESEMS)” (€
125.000,00)
� Novartis Pharma: Studio di un modello murino transgenico per la caratterizzazione del
proteoglicano NG2/CSPG4 nella patogenesi della sclerosi multipla. (€ 45.000,00)
2011
� ITALIAN MINISTRY OF HEALTH “Preclinical evaluation of the NAMPT inhibitor FK866
for the treatment of autoimmunity and lymphoblastic leukemia” Co-PI (€ 631.111,00)
� Biogen “Sponsored Research Agreement (SRA) – Characterization of effect of BG12 on
activated microglia: implication for the treatment of Multiple Sclerosis” (€ 73.500,00)
� Merck Serono “Charaterization of the effects of cladibrine on adaptive immune
responses in mice and humans” (€ 240.000,00)
� Italian Foundation For Multiple Sclerosis (FISM), 2011-2015: “Progetto Speciale 2011-
2014: Cellule Staminali mesenchimali per la terapia della SM”. PI (€ 900.000,00)
� ITALIAN MINISTRY OF UNIVERSITY AND RESEARCH – PRIN 2009 “Identificazione di
nuove sorgenti di cellule staminali per la cura della sclerosi multipla” (€ 278.454,00)
� Italian Foundation for Multiple Sclerosis (FISM): Exploitation of a transgenic mouse
model for the unveiling of the role of proteoglycan NG2/CSPG4 in the pathogenesis of
multiple sclerosis (€ 30.000,00)
Publications on Journals covered by the Institute for Scientific Information
11
(total impact factor: 883,673- mean IF/publication: 5,891)
Dr Uccelli’s C.I. (Citation Index Scopus) is 9427 (Citation Index including publication where AU is part of research groups) is 10.407- H Index is 44.
Prof. Antonio Uccelli is classified 93° in Top Italian Scientists (http://www.topitalianscientists.org)
1. Bommarito G, Bellini A, Pardini M, Solaro C, Roccatagliata L, Laroni A, Capello E,
Mancardi G, Uccelli, Inglese M. Composite MRI measures and short-term disability in
patients with clinically isolated syndrome suggestive of MS. Multiple Sclerosis Journal
2017 accepted for publication. IF: 4.671 CI:0
2. Bukreeva I, Campi G, Fratini M, Spanò R, Bucci D, Battaglia G, Giove F, Bravin A, Uccelli
A, Venturi C, Mastrogiacomo M, Cedola A. Quantitative 3D investigation of Neuronal
network in mouse spinal cord model. Sci Rep. 2017 Jan 23;7:41054 IF:5.228 CI:0
3. Gross CC, Schulte-Mecklenbeck A, Wiendl H, Marcenaro E, Kerlero de Rosbo N, Uccelli
A, Laroni A. Regulatory Functions of Natural Killer Cells in Multiple Sclerosis. Front
Immunol. 2016 Dec 19;7:606. IF: 5.695 CI:0
4. Tintoré M, Alexander M, Costello K, Duddy M, Jones DE, Law N, O'Neill G, Uccelli A,
Weissert R, Wray S. The state of multiple sclerosis: current insight into the
patient/health care provider relationship, treatment challenges, and satisfaction.
PATIENT PREFER ADHER. 2016 Dec 22;11:33-45. IF: 1.718 CI:0
5. Gandoglia I, Ivaldi F, Carrega P, Armentani E, Ferlazzo G, Mancardi G, Kerlero de Rosbo
N, Uccelli A, Laroni A. In vitro VLA-4 blockade results in an impaired NK cell-mediated
immune surveillance against melanoma. Immunol Lett. 2017 Jan;181:109-115. IF:2.483
CI:0
6. Laroni A, Brogi D, Brescia Morra V, Guidi L, Pozzilli C, Comi G, Lugaresi A, Turrini R,
Raimondi D, Uccelli A, Mancardi GL. Safety and tolerability of fingolimod in patients
with relapsing-remitting multiple sclerosis: results of an open-label clinical trial in Italy.
Neurol Sci. 2016 Oct 18 IF:1.783 CI: 0
12
7. Massimi L, Fratini M, Bukreeva I, Brun F, Mittone A, Campi G, Spanò R, Mastrogiacomo
M, de Rosbo NK, Bravin A, Uccelli A, Cedola A Characterization of mouse spinal cord
vascular network by means of synchrotron radiation X-ray phase contrast tomography.
Phys Med. 2016 Dec;32(12):1779-1784 IF:1.763 CI: 0
8. Vigo T, Procaccini C, Ferrara G, Baranzini S, Oksenberg JR, Matarese G, Diaspro A,
Kerlero de Rosbo N, Uccelli A. IFNγ orchestrates mesenchymal stem cells plasticity
through STAT1, STAT3 and mTOR pathways. J ALLERGY CLIN IMMUN. 2016 Sep 23. pii:
S0091-6749(16)31021-1. [Epub ahead of print] IF: 12.485 CI: 0
9. Rozenberg A, Rezk A, Boivin MN, Darlington PJ, Nyirenda M, Li R, Jalili F, Winer R, Artsy
EA, Uccelli A, Reese JS, Planchon SM, Cohen JA, Bar-Or A. Human Mesenchymal Stem
Cells Impact Th17 and Th1 Responses Through a Prostaglandin E2 and Myeloid-
Dependent Mechanism. Stem Cells Transl Med. 2016 Jul 11. [Epub ahead of print] IF:
5.709. CI: 2
10. Annovazzi P, Capobianco M, Moiola L, Patti F, Frau J, Uccelli A, Centonze D, Perini P,
Tortorella C, Prosperini L, Lus G, Fuiani A, Falcini M, Martinelli V, Comi G, Ghezzi A.
Rituximab in the treatment of Neuromyelitis optica: a multicentre Italian observational
study J Neurol. 2016 Sep;263(9):1727-35. Epub 2016 Jun 10 IF: 3.377 CI: 1
11. Laroni A, Armentani E, Kerlero de Rosbo N, Ivaldi F, Marcenaro E, Sivori S, Gandhi R,
Weiner HL, Moretta A, Mancardi GL, Uccelli A. Dysregulation of regulatory
CD56(bright) NK cells/T cells interactions in multiple sclerosis. J Autoimmun. 2016
Aug;72:8-18. Epub 2016 May 4.IF: 8.410 CI: 4
12. Iester M, Cordano C, Costa A, D’Alessandro E, Panizzi A, Bisio F, Masala A, Landi L,
Traverso CE, Ferreras A, Mancardi GL and Uccelli A. Effectiveness of Time Domain and
Spectral Domain Optical Coherence Tomograph to Evaluate Eyes with And Without
Optic Neuritis in Multiple Sclerosi Patients. J Mult Scler (Foster City). 2016 May 17. IF:
1.650 CI: 0
13. Ferrara G, Errede M, Girolamo F, Morando S, Ivaldi F, Panini N, Bendotti C, Perris R,
Furlan R, Virgintino D, Kerlero de Rosbo N, Uccelli A. NG2, a common denominator for
13
neuroinflammation, blood-brain barrier alteration, and oligodendrocyte precursor
response in EAE, plays a role in dendritic cell activation. Acta Neuropathol. 2016 Mar
30. [Epub ahead of print] IF: 11.360 CI:0
14. Mattioli F, Bellomi F, Stampatori C, Provinciali L, Compagnucci L, Uccelli A, Pardini M,
Santuccio G, Fregonese G, Pattini M, Allegri B, Clerici R, Lattuada A, Montomoli C, Corso
B, Gallo P, Riccardi A, Ghezzi A, Roscio M, Tola MR, Calanca C, Baldini D, Trafficante D,
Capra R. Two years follow up of domain specific cognitive training in relapsing
remitting multiple sclerosis: a randomized clinical trial. Front Behav Neurosci. February
2016 IF: 3,392 CI: 0
15. Lasigliè D, Boero S, Bauer I, Morando S, Damonte P, Odetti P, Ballestrero A, Uccelli A,
Mostoslavsky R, Poggi A, Nencioni A. Sirt6 regulates dendritic cells differentiation,
maturation and function. Aging (Albany NY) 2016 Jan 12. [Epub ahead of print] IF:3.979
CI: 1
16. Mattioli F, Stampatori C, Bellomi F, Danni M, Compagnucci L, Uccelli A, Pardini M,
Santuccio G, Fregonese G, Pattini M, Allegri B, Clerici R, Lattuada A, Montomoli C, Corso
B, Capra R. A RCT Comparing Specific Intensive Cognitive Training to Aspecific
Psychological Intervention in RRMS: The SMICT Study. Front Neurol. 2015 Jan 13;5:278.
IF 3.184 CI: 3
17. Benvenuto F, Voci A, Carminati E, Gualandi F, Mancardi G, Uccelli A, Vergani L. Human
mesenchymal stem cells target adhesion molecules and receptors involved in T cell
extravasation. Stem Cell Res Ther. 2015 Dec 10;6(1):245 IF: 4.504 CI: 4
18. Moretta L, Uccelli A, Pistoia V. Mesenchymal stromal cells and immunity: Introductory
overview. Immunol Lett. 2015 Dec;168(2):127-8 Epub 2015 Sep 2 IF: 2.483 CI: 1
19. Laroni A, Rosbo NK, Uccelli A Mesenchymal stem cells for the treatment of neurological
diseases: immunoregulation beyond neuroprotection. Immunol Lett. 2015
Dec;168(2):183-90. Epub 2015 Aug 18. IF: 2.483 CI: 1
14
20. Uccelli A, de Rosbo NK. The immunomodulatory function of mesenchymal stem cells:
mode of action and pathways. Ann NY Acad Sci. 2015 Sep;1351:114-26 2015 Jul 6 IF:
4.518 CI: 13
21. Parodi B, Rossi S, Morando S, Cordano C, Bragoni A, Motta C, Usai C, Wipke BT,
Scannevin RH, Mancardi GL, Centonze D, Kerlero de Rosbo N, Uccelli A. Fumarates
modulate microglia activation through a novel HCAR2 signaling pathway and rescue
synaptic dysregulation in inflamed CNS. Acta Neuropathol. 2015 Aug;130(2):279-95.
Epub 2015 Apr 29. IF: 11.360 CI:22
22. Kuhle J, Disanto G, Dobson R, Adiutori R, Bianchi L, Topping J, Bestwick J, Meier UC,
Marta M, Costa GD, Runia T, Evdoshenko E, Lazareva N, Thouvenot E, Iaffaldano P,
Direnzo V, Khademi M, Piehl F, Comabella M, Sombekke M, Killestein J, Hegen H, Rauch
S, D'Alfonso S, Alvarez-Cermeño J, Kleinová P, Horáková D, Roesler R, Lauda F, Llufriu S,
Avsar T, Uygunoglu U, Altintas A, Saip S, Menge T, Rajda C, Bergamaschi R, Moll N, Khalil
M, Marignier R, Dujmovic I, Larsson H, Malmestrom C, Scarpini E, Fenoglio C, Wergeland
S, Laroni A, Annibali V, Romano S, Martínez A, Carra A, Salvetti M, Uccelli A, Torkildsen
Ø, Myhr K, Galimberti D, Rejdak K, Lycke J, Frederiksen J, Drulovic J, Confavreux C,
Brassat D, Enzinger C, Fuchs S, Bosca I, Pelletier J, Picard C, Colombo E, Franciotta D,
Derfuss T, Lindberg R, Yaldizli Ö, Vécsei L, Kieseier B, Hartung H, Villoslada P, Siva A,
Saiz A, Tumani H, Havrdová E, Villar L, Leone M, Barizzone N, Deisenhammer F,
Teunissen C, Montalban X, Tintoré M, Olsson T, Trojano M, Lehmann S, Castelnovo G,
Lapin S, Hintzen R, Kappos L, Furlan R, Martinelli V, Comi G, Ramagopalan S, Giovannoni
G Conversion from clinically isolated syndrome to multiple sclerosis: A large
multicentre study. Multiple Sclerosis Journal 2015 Jul;21(8):1013-24. Epub 2015 Feb
13. IF: 4.671. CI:43
23. Mancardi GL, Sormani MP, Gualandi F, Saiz A, Carreras E, Merelli E, Donelli A, Lugaresi
A, Di Bartolomeo P, Rottoli MR, Rambaldi A, Amato MP, Massacesi L, Di Gioia M, Vuolo L,
Currò D, Roccatagliata L, Filippi M, Aguglia U, Iacopino P, Farge D, Saccardi R; For the
ASTIMS Haemato-Neurological Collaborative Group, On behalf of the Autoimmune
Disease Working Party (ADWP) of the European Group for Blood and Marrow
Transplantation (EBMT)*. Autologous hematopoietic stem cell transplantation in
multiple sclerosis: A phase II trial. Neurology. 2015 Mar 10;84(10):981-8. Epub 2015
Feb 11 IF: 8.166 CI: 44
15
a. *A. Uccelli is part of the European Group for Blood and Marrow Transplantation
(EBMT)
24. Curro' D, Vuolo L, Gualandi F, Bacigalupo A, Roccatagliata L, Capello E, Uccelli A,
Saccardi R, Sormani MP, Mancardi G. Low intensity lympho-ablative regimen followed
by autologous hematopoietic stem cell transplantation in severe forms of multiple
sclerosis: A MRI-based clinical study. Multiple Sclerosis Journal 2015 Jan 12 IF: 4.671
CI: 4
25. Marinelli L, Mori L, Solaro C, Uccelli A, Pelosin E, Currà A, Molfetta L, Abbruzzese G,
Trompetto C. Effect of radial shock wave therapy on pain and muscle hypertonia: a
double-blind study in patients with multiple sclerosis. Multiple Sclerosis Journal. 2015
Apr;21(5):622-9. Epub 2014 Sep 25 IF: 4.671 CI:2
26. Tacchino A, Bove M, Roccatagliata L, Luigi Mancardi G, Uccelli A, Bonzano L. Selective
impairments of motor sequence learning in multiple sclerosis patients with minimal
disability. Brain Res. Oct 17;1585:91-8. Epub 2014 Aug 20. IF: 2.561 CI:2
27. Pardini M, Bonzano L, Bergamino M, Bommarito G, Feraco P, Murugavel A, Bove M,
Brichetto G, Uccelli A, Mancardi G, Roccatagliata L. Cingulum bundle alterations underlie
subjective fatigue in multiple sclerosis. Multiple Sclerosis Journal. 2015 Apr;21(4):442-
7. Epub 2014 Aug 21 IF: 4.671 CI:4
28. Laroni A, Gandoglia I, Solaro C, Ribizzi G, Tassinari T, Pizzorno M, Parodi S, Baldassarre
G, Rilla MT, Venturi S, Capello E, Sormani MP, Uccelli A, Mancardi GL Clinical baseline
factors predict response to natalizumab: their usefulness in patient selection. BMC
Neurol. 2014 May 12;14:103. IF: 1.961 CI: 3
29. Laroni A, Brogi D, Morra VB, Guidi L, Pozzilli C, Comi G, Lugaresi A, Turrini R, Raimondi
D, Uccelli A, Mancardi GL. Safety of the first dose of fingolimod for multiple sclerosis:
results of an open-label clinical trial. BMC NEUROL. 2014 Apr 1;14(1):65. IF: 1.961 CI:
23
16
30. Pardini M, Uccelli A, Grafman J, Yaldizli O, Mancardi G, Roccatagliata L. Isolated
cognitive relapses in multiple sclerosis. J NEUROL NEUROSUR PS. 2014 Sep;85(9):1035-
7. Epub 2014 Mar 31. IF: 6.431 CI:14
31. Di Prisco S, Merega E, Lanfranco M, Casazza S, Uccelli A, Pittaluga A. Acute desipramine
restores presynaptic cortical defects in murine experimental autoimmune
encephalomyelitis by suppressing central CCL5 overproduction. Brit J Pharmacol. 2014
May;171(9):2457-67IF: 5.259 CI:6
32. Giunti D., Parodi B, Cordano C, Uccelli A, Kerlero de Rosbo N. Can we switch microglia's
phenotype to foster neuroprotection? Focus on multiple sclerosis. Immunology. 2014
Mar;141(3):328-39 IF: 4.078 CI:26
33. Di Prisco S, Merega E, Milanese M, Summa M, Casazza S, Raffaghello L, Pistoia V, Uccelli
A, Pittaluga A. CCL5-glutamate interaction in central nervous system: Early and acute
presynaptic defects in EAE mice. Neuropharmacology. 2013 Dec 75:337-46. Epub 2013
Aug 16 IF: 4.936 CI:10
34. Bonzano L, Sormani MP, Tacchino A, Abate L, Lapucci C, Mancardi GL, Uccelli A, Bove M.
Quantitative assessment of finger motor impairment in multiple sclerosis. PLoS One.
2013 May 31; 8(5):e65225 IF: 3.057 CI:10
35. Serpero LD, Filaci G, Parodi A, Battaglia F, Kalli F, Brogi D, Mancardi GL, Uccelli A,
Fenoglio D. Fingolimod Modulates Peripheral Effector and Regulatory T Cells in MS
Patients. J NEUROIMMUNE PHARM. Dec;8(5):1106-13. Epub 2013 May 7IF: 3.896 CI: 27
36. Laroni A, Novi G, Kerlero de Rosbo N, Uccelli A. Towards Clinical Application of
Mesenchymal Stem Cells for Treatment of Neurological Diseases of the Central Nervous
System. J NEUROIMMUNE PHARM. 2013 Dec;8(5):1062-76. Epub 2013 Apr 12 IF: 3.896
CI: 16
37. Morandi F., Venturi C., Rizzo R., Castellazzi M., Baldi E., Caniatti ML., Tola MR., Granieri
E., Fainardi E., Uccelli A., Pistoia V., Intrathecal soluble HLA-E correlates with disease
activity in patients with multiple sclerosis and may cooperate with soluble HLA-G in the
17
resolution of neuroinflammation J NEUROIMMUNE PHARM. 2013 Sep;8(4):944-55.
Epub 2013 Apr 28. IF: 3.896 CI: 15
38. Montecucco F, Cea M, Bauer I, Soncini D, Caffa I, Lasigliè D, Nahimana A, Uccelli A,
Bruzzone S, Nencioni A. Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
As Therapeutics: Rationales, Controversies, Clinical Experience. Curr Drug Targets.
2013 Jun 1;14(6):637-43. IF: 3.029 CI:20
39. Uccelli A. Mesenchymal stem cells exert a remarkable regenerative effect requiring
minimal CNS integration: Commentary on: "Mesenchymal stem cells protect CNS
neurons against glutamate excitotoxicity by inhibiting glutamate receptor expression
and function" by Voulgari-Kokota et al. Exp Neurol. 2013 Sep;247:292-5. Epub 2013
Feb 4. IF: 4.657 CI: 11
40. Laroni A, Brogi D, Milesi V, Abate L, Uccelli A, Mancardi G. Early switch to fingolimod
may decrease the risk of disease recurrence after natalizumab interruption. Multiple
Sclerosis Journal 2013 Aug;19(9):1236-7. Epub 2012 Nov 26 IF: 4.671 CI: 21
41. Uccelli A, Laroni A, Freedman MS. Mesenchymal stem cells as treatment for MS –
progress to date". Multiple Sclerosis Journal 2013 Apr;19(5):515-9. Epub 2012 Nov 1.
IF: 4.671 CI:25
42. Errede M, Girolamo F, Ferrara G, Strippoli M, Morando S, Boldrin V, Rizzi M, Uccelli A,
Perris R, Bendotti C, Salmona M, Roncali L, Virgintino D. Blood-Brain Barrier Alterations
in the Cerebral Cortex in Experimental Autoimmune Encephalomyelitis. J NEUROPATH
EXP NEUR 2012 Oct;71(10):840-854. IF: 3,432 CI: 23
43. Giunti D, Parodi B, Usai C, Vergani L, Casazza S, Bruzzone S, Mancardi G, Uccelli A.
Mesenchymal Stem Cells Shape Microglia Effector Functions Through the Release of
CX3CL1. Stem Cells. 2012 Sep;30(9):2044-53. IF: 5.902 CI:53
44. Sallusto F, Impellizzieri D, Basso C, Laroni A, Uccelli A, Lanzavecchia A, Engelhardt B. T-
cell trafficking in the central nervous system. Immunol Rev. 2012 Jul;248(1):216-27. IF:
9.542 CI: 57
18
45. Pardini M, Capello E, Krueger F, Mancardi G, Uccelli A. Reward responsiveness and
fatigue in multiple sclerosis. Multiple Sclerosis Journal 2013 Feb;19(2):233-40. Epub
2012 Jun 21. IF: 4.671 CI:7
46. Laroni A, Giacomazzi CG, Grimaldi L, Gallo P, Sormani MP, Bertolotto A, McDermott JL,
Gandoglia I, Martini I, Vitello G, Rinaldi F, Barzon L, Militello V, Pizzorno M, Bandini F,
Capello E, Palù G, Uccelli A, Mancardi GL, Varnier OE Urinary JCV-DNA Testing during
Natalizumab Treatment May Increase Accuracy of PML Risk Stratification. J
NEUROIMMUNE PHARM. 2012 Sep;7(3):665-72. Epub 2012 May 16 IF: 3.896 CI:20
47. Mirabelli-Badenier M, Morana G, Pinto F, Uccelli A, Veneselli E, Battaglia FM, Biancheri
R, Baglietto MG, Vincent A, Mancardi MM. Anti-Glutamic Acid Decarboxylase Limbic
Encephalitis Without Epilepsy Evolving into Dementia with Cerebellar Ataxia. ARCH
NEUROL-CHICAGO. 2012 Aug;69(8):1064-6. IF: 7.419 CI: 8
48. Uccelli A, Milanese M, Principato MC, Morando S, Bonifacino T, Vergani L, Giunti D, Voci
A, Carminati E, Giribaldi F, Caponnetto C, Bonanno G. Intravenous mesenchymal stem
cells improve survival and motor function in experimental amyotrophic lateral
sclerosis. Mol Med. 2012 Jul 18;18:794-804.. IF: 3.530 CI: 54
49. Lugaresi A., Florio C., Brescia-Morra V., Cottone S., Bellantonio P., Clerico M., Centonze
D., Uccelli A., Di Ioia M., De Luca G., Marcellusi A., Paolillo A. and the BRIDGE Study
group. Patient adherence to and tolerability of self-administered interferon beta-1a
using an electronic autoinjection device: a multicentre, open-label, phase IV study” BMC
Neurol 2012 March 5, 12:7. IF: 1.961 CI: 26
50. Freedman MS, Uccelli A. Neurorepair with mesenchymal stem cells: hope or hype?
Lancet Neurol. 2012 Feb;11(2):123-5. Epub 2012 Jan 10 IF: 23.468 CI:6
51. Morando S, Vigo T, Esposito M, Casazza S, Novi G, Principato MC, Furlan R, Uccelli A.
The therapeutic effect of mesenchymal stem cells transplantation in experimental
autoimmune encephalomyelitis is mediated by peripheral and central mechanisms.
Stem Cell Res Ther. 2012 Jan 26;3(1):3. IF: 4.504 CI: 37
19
52. Mancardi G, Sormani M, Di Gioia M, Vuolo L, Gualandi F, Amato M, Capello E, Currò
D, Uccelli A, Bertolotto A, Gasperini C, Lugaresi A, Merelli E, Meucci G, Motti L, Tola M,
Scarpini E, Repice A, Massacesi L, Saccardi R. Autologous haematopoietic stem cell
transplantation with an intermediate intensity conditioning regimen in multiple
sclerosis: the Italian multi-centre experience. Multiple Sclerosis Journal. 2012
Jun;18(6):835-42. Epub 2011 Nov 29. IF: 4.671 CI:39
53. Conti L, De Palma R, Rolla S, Boselli D, Rodolico G, Kaur S., Silvennoinen O, Niccolai E,
Amedei A, Ivaldi F, Clerico M, Contessa G, Uccelli A, Durelli L, Novelli F. Th17 cells in
multiple sclerosis express higher levels of JAK2, which increases their surface
expression of IFN-γR2. J Immunol. 2012 Feb 1;188(3):1011-8 IF: 4.895 CI:10
54. Chiesa S, Morbelli S, Morando S, Massollo M, Marini C, Bertoni A, Frassoni F, Tabera
Bartolomé S, Sambuceti G, Traggiai E, Uccelli A. Mesenchymal stem cells impair in vivo
T cell priming by dendritic cells. P NATL ACAD SCI USA (PNAS) 2011 Oct
18;108(42):17384-9. Epub 2011 Sep 29 IF: 9.423 CI:112
55. Ghezzi A, Carone R, Del Popolo G, Amato MP, Bertolotto A, Comola M, Del Carro U, Di
Benedetto P, Giannantoni A, Lopes de Carvalho ML, Montanari E, Patti F, Protti A, Rasia
S, Salonia A, Scandellari C, Sperli F, Spinelli M, Solaro C, Uccelli A, Zaffaroni M, Zipoli V;
The Multiple Sclerosis Study Group, Italian Society of Neurology. Recommendations for
the management of urinary disorders in multiple sclerosis: a consensus of the Italian
Multiple Sclerosis Study Group. Neurol Sci. 2011 Dec;32(6):1223-31. IF: 1.783 CI:9
56. Laroni A, Giacosa A, Uccelli A, Mancardi GL. Can we kill an extra bird with the same
stone? Inflamm Bowel Dis. 2011 Jun; 17(9):124-125. IF: 4.358 CI: 0
57. Uccelli A, Laroni A, Freedman MS Mesenchymal stem cells for the treatment of multiple
sclerosis and other neurological diseases. Lancet Neurol. 2011 Jul;10(7):649-56 IF:
23.468 CI: 132
58. Oddo S, Laroni A, Uccelli A, Giusti M A case of thyroiditis during natalizumab therapy
for multiple sclerosis. J Endocrinol Invest. 2011 May;34(5):408-9. IF: 1.994 CI:2
20
59. Uccelli A, Ginocchio F, Mancardi GL, Bassetti M. Primary varicella zoster infection
associated with fingolimod treatment. Neurology. 2011 Mar 15;76(11):1023-4. IF:
8.166 CI: 27
60. Uccelli A, Benvenuto F, Laroni A, Giunti D. Neuroprotective features of mesenchymal
stem cells. Best Pract Res Cl Ha. 2011 Mar;24(1):59-64. Epub 2011 Feb 25. IF 2.740
CI:106
61. A Laroni, M Bedognetti, A Uccelli, E Capello, GL Mancardi Association of melanoma and
natalizumab therapy in the Italian MS population: a second case report
Neurol Sci. 2011 Feb; 32(1):181-182 IF: 1.783 CI: 13
62. Marte A, Cavallero A, Morando S, Uccelli A, Raiteri M, Fedele E. Alterations of glutamate
release in the spinal cord of mice with experimental autoimmune encephalomyelitis. J
Neurochem. 2010 Oct;115(2):343-52. IF 3.842 CI: 6
63. Perasso, L, Cogo CE, Giunti D, Gandolfo C, Ruggeri P, Uccelli A, Balestrino M, Systemic
Administration of Mesenchymal Stem Cells Increases Neuron Survival after Global
Cerebral Ischemia In Vivo (2VO). Neural Plast. 2010 2010:534925. Epub 2010 Dec 19IF:
3.568 CI:15
64. Uccelli A, Prockop DJ. Why should mesenchymal stem cells (MSCs) cure autoimmune
diseases? Curr Opin Immunol. 2010 Dec;22(6):768-74. Epub 2010 Nov 17. IF: 7.126
CI:84
65. Fruscione F, Scarfì S, Ferraris C, Bruzzone S, Benvenuto F, Guida L, Uccelli A, Salis A,
Usai C, Jacchetti E, Ilengo C, Scaglione S, Quarto R, Zocchi E, De Flora A. Regulation of
human mesenchymal stem cell functions by an autocrine loop involving NAD+ release
and P2Y11-mediated signaling. Stem Cells Dev. 2011 Jul;20(7):1183-98. Epub 2010 Dec
22. IF: 3.777 CI:27
21
66. Uccelli A, Morando S, Bonanno S, Bonanni I, Leonardi A, Mancardi G. Mesenchymal
Stem Cells for Multiple Sclerosis: Does Neural Differentiation Really Matter? CURR
STEM CELL RES T. 2011 Mar;6(1):69-72. Review. IF: 2.645 NA CI: 15
67. Muraro PA, Uccelli A. Immuno-Therapeutic Potential of Haematopoietic and
Mesenchymal Stem Cell Transplantation in MS. Results Probl Cell Differ. 2010;51:237-
57.IF:2.210 CI:7
68. Massollo M, Podestà M, Marini C, Morbelli S, Cassanelli C, Pinto V, Ubezio G, Curti G,
Uccelli A, Frassoni F, Sambuceti G. Contact with the bone marrow microenvironment
readdresses the fate of transplanted hematopoietic stem cells. Exp Hematol. 2010
Oct;38(10):968-77. IF: 2.303 CI:11
69. Schena F, Gambini C, Gregorio A, Mosconi M, Reverberi D, Gattorno M, Casazza S, Uccelli
A, Moretta L, Martini A, Traggiai E. IFN-gamma dependent inhibition of B cell activation
by bone marrow derived mesenchymal stem cells in a murine model of systemic lupus
erythematosus. Arthritis rheum-us. 2010 Sep;62(9):2776-86. IF: 8.955 CI:67
70. Martino G, Franklin RJ, Van Evercooren AB, Kerr DA. Stem cell transplantation in
multiple sclerosis: current status and future prospects. Nat Rev Neurol. 2010
May;6(5):247-55. *U.A. contributed to this work. IF: 18.418 CI:110
71. Uccelli A, Mancardi GL. Stem cell transplantation in multiple sclerosis. Curr Opin
Neurol. 2010 Jun. 23(3):218-25. IF: 4.469 CI:32
72. Freedman MS, Bar-Or A, Atkins HL, Karussis D, Frassoni F, Lazarus H, Scolding N, Le
Blanc K, Uccelli A. The therapeutic potential of mesenchymal stem cell transplantation
as a treatment for multiple sclerosis: consensus report of the International MSCT Study
Group. Multiple Sclerosis Journal 2010. 16(4): 503-510. IF: 4.671 CI:125
73. Sormani MP, Bonzano L, Roccatagliata L, Mancardi GL, Uccelli A, Bruzzi P. Surrogate
endpoints for EDSS worsening in Multiple Sclerosis: A meta-analytic approach.
Neurology 2010. July 27;75(4):302-9. IF: 8.166 CI:72
22
74. Capello E, Vuolo L, Gualandi F, Van Lint MT, Roccatagliata L, Bonzano L, Pardini M,
Uccelli A, Mancardi G. Autologous haematopoietic stem-cell transplantation in multiple
sclerosis: benefits and risks. Neurol Sci. 2009 Oct;30 Suppl 2:S175-7. IF: 1.783 CI:8
75. Bruzzone S, Fruscione F, Morando S, Ferrando T, Poggi A, Garuti A, D'Urso A, Selmo M,
Benvenuto F, Cea M, Zoppoli G, Moran E, Soncini D, Ballestrero A, Sordat B, Patrone F,
Mostoslavsky R, Uccelli A, Nencioni A. Catastrophic NAD+ depletion in activated T
lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.
PLoS One.2009 Nov 19;4(11):e7897. IF: 3.057 CI:77
76. Lanza C., Morando S., Voci A, Canesi L., Principato M.C., Serpero L., Mancardi GL, Uccelli
A., Vergani, L. Neuroprotective Mesenchymal Stem Cells are endowed with a potent
antioxidant effect in vivo. J Neurochem. 2009 Feb;30(1):21-31. 2009. IF 3.842 CI:105
77. Tyndall A, Uccelli A. Multipotent mesenchymal stromal cells for autoimmune diseases:
teaching new dogs old tricks. Bone Marrow Transpl. 2009 Mar Jun;43(11):821-8. Epub
2009 Mar 23. IF: 3.636. CI:79
78. Reboldi A, Cosine C, Baumjohann D, Benvenuto F, Bottinelli D, Lira S, Uccelli A,
Lanzavecchia A, Engelhardt B, Sallusto F. C-C chemokine receptor 6-regulated entry of
T(H)-17 cells into the CNS through the choroid plexus is required for the initiation of
EAE. Nat Immunol. 2009 May;10(5):514-23. Epub 2009 Mar 22. IF: 19.381 CI:544
79. Prigione I, Benvenuto F, Bocca P, Battistini L, Uccelli A, Pistoia V. Reciprocal
Interactions between Human Mesenchymal Stem Cells and {gamma}{delta} T Cells or
Invariant Natural Killer T (iNKT) Cells. Stem Cells. 2009 Mar; 27(3):693-702. *U.A. e
P.V. contributed equally to this work. IF: 5.902. CI:94
80. Lazzaro C., Bianchi C, Peracino L, Verdun E., Zacchetti P, Uccelli A. Economic Evaluation
Of Treating Clinically Isolated Syndrome And Subsequent Multiple Sclerosis With
Interferon beta 1b. Neurol Sci. 2009 Feb;30(1):21-31. Epub 2009 Jan 24. IF: 1.783 CI:21
81. Uccelli A. Adult stem cells for spinal cord injury: what types and how do they work?
Cytotherapy. 2008;10(6):541-2. IF: 3.625. CI:2
23
82. Uccelli A, Moretta L, Pistoia V. Mesenchymal stem cells: role in health and disease. Nat
Rev Immunol. 2008 Sep;8(9):726-36. IF: 34.416 CI:1382
83. Uccelli A, Mancardi Gl, Chiesa S. Is there a role for mesenchymal stem cells in
autoimmune diseases? Autoimmunity. 2008 Dec;41(8):592-5. IF: 2.917. CI:31
84. Villoslada P, Moreno B, Meleto I, de Pablos JL, Martino G, Uccelli A, Montalban X, Avila
J, Rivest S, Acarin L, Appel S, Khoury S, McGeer P, Ferrer I, Delgado M, Obeso J,
Schwartz M. Immunotherapy for neurological diseases. Clin Immunol. 2008,
Sep;128(3):294-305. Epub 2008 Jun 4IF: 4.034. CI:31
85. Cocco E, Sardu C, Gallo P, Capra R, Amato MP, Trojano M, Uccelli A, Marrosu MG and
the FEMIMS group. Frequency and risk factors of mitoxantrone-induced amenorrhea in
multiple sclerosis: the FEMIMS study. Multiple Sclerosis Journal 2008 Nov;14(9):1225-
33. Epub 2008 Aug 13. IF: 4.671 CI:38
86. Trompetto C, Avanzino L, Bove M, Buccolieri A, Uccelli A, Abbruzzese G. Investigation
of paroxysmal dystonia in a patient with multiple sclerosis: A transcranial magnetic
stimulation study. Clin Neurophysiol. 2008 Jan;119(1):63-70. Epub 2007 Nov 26. IF:
3.426. CI:11
87. Sessarego N, Parodi A, Podestà M, Benvenuto F, Mogni M, Raviolo V, Lituania M, Kunkl
A, Ferlazzo G, Bricarelli FD, Uccelli A, Frassoni F. Amniotic fluid contains multipotent
mesenchymal stromal cells with high proliferative potential and safety features: solid
perspectives for clinical application. HAEMATOLOGICA. 2008 Mar;93(3):339-46. Epub
2008 Feb 11. IF: 6.671. CI:101
88. Gualandi F, Bruno B, Van Lint MT, Luchetti S, Uccelli A, Capello E, Mancardi GL,
Bacigalupo A, Marmont A. Autologous stem cell transplantation for severe autoimmune
diseases: a 10-year experience. Ann Ny Acad Sci. 2007 Sep;1110:455-64. IF: 4.518
CI:24
24
89. Iester M, Cioli F, Uccelli A, Papadia M, Bandini F, Mancardi GL, Calabria GA. Retinal
nerve fibre layer measurements and optic nerve head analysis in multiple sclerosis
patients. Eye 2009 Feb;23(2):407-12. Epub 2007 Nov 9. IF: 2.213 CI:14
90. Riverol M, Sepulcre J, Fernandez-Diez B, Villoslada P, Fernandez-Alonso M, Rubio M,
Rodriguez A, Uccelli A, Brieva L. Antibodies against Epstein-Barr virus and
herpesvirus type 6 are associated with the early phases of Multiple Sclerosis. J
Neuroimmunol 2007. Dec;192(1-2):184-5. Epub 2007 Sep 14. IF: 2.536 CI:14
91. Benedetti L, Franciotta D, Vigo T, Grandis M, Fiorina E, Ghiglione E, Roccatagliata L,
Mancardi GL, Uccelli A, Schenone A. Post-rituximab relapse in a multiple sclerosis
patient with anti-mag polyneuropathy. ARCH NEUROL-CHICAGO. 2007.
Oct;64(10):1531-3. IF:7.419 CI: 17
92. Uccelli A, Pistoia V, Moretta L. Mesenchymal stem cells: a new strategy for
immunosuppression? Trends Immunol. 2007 May;28(5):219-26. Epub 2007 Apr 2. IF:
11.433 CI:291
93. Kobelt G, Berg J, Lindgren P, Battaglia M, Lucioni C, Uccelli A. Costs and quality of life of
multiple sclerosis in Italy. Eur J Health Econ. 2007 Sep;7 Suppl 2:S45-54. IF:2.266 CI:27
94. Uccelli A, Frassoni F, Mancardi GL. Stem cells for multiple sclerosis: promise and
reality. Regen Med. 2007 Jan;2(1):7-9. IF: 2.602. CI:6
95. Tyndall A, Walker U, Cope A, Dazzi F, De Bari C, Fibbe WE, Guiducci S, Jones SP,
Jorgensen C, Le Blanc K, Luyten F, McGonagle DG, Martin I, Bocelli-Tyndall C, Pennesi G,
Pistoia V, Pitzalis C, Uccelli A, Wulffraat N, Feldmann M. Immunomodulatory
properties of mesenchymal stem cells: a review based on an interdisciplinary meeting
held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005.
Arthritis Res Ther. 2007 Jan 29;9(1): 301 IF: 3.979. CI:76
96. Benvenuto F, Ferrari S, Gerdoni E, Gualandi F, Frassoni F, Pistoia V, Mancardi GL,
Uccelli A. Human mesenchymal stem cells promote survival of T cells in a quiescent
state. Stem cells. 2007 Jul;25(7):1753-60. 2007 Mar 29. IF: 5.902 CI:130
25
97. Gerdoni E, Gallo B, Casazza S, Musio S, Bonanni I, Pedemonte E, Mantegazza R, Frassoni
F, Mancardi GL, Pedotti R, Uccelli A. Mesenchymal stem cells effectively modulate
pathogenic immune response in EAE. Ann Neurol. 2007. Mar;61(3):219-27. IF: 9.638.
CI:309
98. Pedemonte E, Benvenuto F, Casazza S, Mancardi GL, Oksenberg JR, Uccelli A, Baranzini
S. The molecular signature of therapeutic mesenchymal stem cells exposes the
architecture of the hematopoietic stem cell niche synapse. BMC Genomics. 2007 Mar
6;8(1):65]. IF: 3.867. CI:50
99. Solaro C, Mantegazza R, Bacigalupo A, Uccelli A. Intractable myoclonus associated with
anti-GluR3 antibodies after allogeneic bone marrow transplantation.
HAEMATOLOGICA. 2006 Dec;91(12 Suppl):ECR62. IF: 6.671 CI:4
100. Uccelli A, Moretta L, and Pistoia V. Immunoregulatory function of mesenchymal stem
cells. Eur J Immunol. 2006 Oct;36(10):2566-73. IF: 4.179. CI:335
101. Barcellos LF, Sawcer S, Ramsay PP, Baranzini SE, Thomson G, Briggs F, Cree B, Begovich
AB, Villoslada P, Montalban X, Uccelli A, Savettieri G, Lincoln RL, DeLoa C, Haines JL,
Pericak-Vance MA, Compston A, Hauser SL, and Oksenberg JR. Heterogeneity at the
HLA-DRB1 locus and risk for multiple sclerosis. HUM MOL GENET 2006 Sep
15;15(18):2813-24. Epub 2006 Aug 11 IF: 5.985. CI:201
102. Uccelli A, Zappia E, Benvenuto F, Frassoni F, Mancardi G. Stem cells in inflammatory
demyelinating disorders: a dual role for immunosuppression and neuroprotection.
Expert Opin Biol Th. 2006 Jan; 6(1):17-22. IF: 3.438. CI:62
103. Corcione A, Benvenuto F, Ferretti E, Giunti D, CappielloV, Cazzanti F, Risso M, Gualandi
F, Mancardi GL, Pistoia V, Uccelli A. Human mesenchymal stem cells modulate B cells
functions. Blood. 2006 Jan 1;107(1):367-72. Epub 2005 Sep. IF: 11.847. CI:882
104. Pedemonte E, Mancardi G, Giunti D, Corcione A, Benvenuto F, Pistoia V, Uccelli A. 2005
Mechanisms of the adaptive immune response inside the central nervous system
26
during inflammatory and autoimmune diseases. Pharmacol Therapeut. 2006
Sep;111(3):555-66. Epub 2006 Jan 26. IF: 11 CI:22
105. Corallo G, Cincinelli S, Papadia M, Bandini F, Uccelli A, Calabria G. Conventional
perimetry, short-wavelength automated perimetry, frequency-doubling technology,
and visual evoked potentials in the assessment of patients with multiple sclerosis. Eur J
Ophthalmol. 2005 Nov-Dec;15(6):730-8. IF: 1.007 CI:16
106. Capello E, Saccardi R, Murialdo A, Gualandi F, Pagliai F, Bacigalupo A, Marmont A,
Uccelli A, Inglese M, Bruzzi P, Sormani MP, Cocco E, Meucci G, Massacesi L, Bertolotto
A, Lugaresi A, Merelli E, Solari A, Filippi M, Mancardi GL; and the Italian GITMO-Neuro
Intergroup on ASCT for Multiple Sclerosis. Intense immunusoppression followed by
autologous stem cell transplantation in severe multiple sclerosis. Neurol Sci. 2005 Dec;
26(supplement 4): s200-s203. IF: 1.783 CI:11
107. Furlan R, Rovaris M, Martinelli Boneschi F, Khademi M, Bergami A, Gironi M, Deleidi M,
Agosta F, Franciotta D, Scarpini E, Uccelli A, Zaffaroni M, Kurne A, Comi G, Olsson T,
Filippi M, Martino G. Immunological patterns identifying disease course and evolution
in multiple sclerosis patients. J Neuroimmunol. 2005 Aug; 165(1-2): 192-200. IF: 2.536
CI:31
108. Zappia E, Casazza S, Pedemonte E, Benvenuto F, Bonanni I, Gerdoni E, Giunti D,
Ceravolo A, Cazzanti F, Frassoni F, Mancardi G, Uccelli A. Mesenchymal stem cells
ameliorate experimental autoimmune encephalomyelitis inducing T cell anergy. Blood.
2005 Sep 1; 106(5): 1755-61. Epub 2005 May 19. IF:11.847 CI: 920
109. Corcione A, Aloisi F, Serafini B, Capello E, Mancardi G, Pistoia V, Uccelli A. B Cell
differentiation in the CNS of patients with multiple sclerosis. Autoimmunity Rev. 2005
Nov;4(8):549-54. IF: 8.49. CI:44
110. Uccelli A, Aloisi F, Pistoia V. Unveiling the enigma of the central nervous system as a
favourable environment for the induction of humoral immunity Trends Immunol. May
2005 5:254-9. IF: 11.433. CI:58
27
111. Mancardi G, Murialdo A, Rossi P, Gualandi F, Martino G, Marmont A, Ciceri F, Schenone
A, Parodi RC, Capello E, Comi G, Uccelli A. Autologous stem cell transplantation as
rescue therapy in malignant forms of multiple sclerosis. Multiple Sclerosis Journal.
2005 Jun; 11(3): 367-71. IF: 4.671 CI:51
112. Saccardi R, Mancardi G, Solari A, Bosi A, Bruzzi P, Di Bartolomeo P, Donelli A, Filippi M,
Guerrasio A, Gualandi F, La Nasa G, Murialdo A, Pagliai F, Papineschi F, Scappini B,
Marmont AM, on behalf of the Italian GITMO-Neuro Intergroup*. 2005. Autologous
HSCT for severe progressive Multiple Sclerosis in a multicenter trial: impact on disease
activity and quality of life. Blood. 2005 Mar 15;105(6):2601-7. IF:11.867. CI: 122
i. U.A. is part of Italian GITMO-Neuro Intergroup
113. Gattorno M, Prigione I, Morandi F, Gregorio A, Chiesa S, Ferlito F, Favre A, Uccelli A,
Gambini C, Martini A, Pistoia V. 2005. Phenotypic and functional characterisation of
CCR7+ and CCR7- CD4+ memory T cells homing to the joints in juvenile idiopathic
arthritis. Arthritis Res Ther. 2005;7(2):R256-67. Epub 2005 Jan 12 IF: 3.979. CI:43
114. Corcione A, Casazza S, Ferretti E, Giunti D, Zappia E, Pistorio A, Gambini C, Mancardi G,
Uccelli A*, Pistoia V*. 2004. Recapitulation of B cell differentiation in the central
nervous system of patients with Multiple Sclerosis. P NATL ACAD SCI USA. 2004 Jul
27;101(30):11064-9. IF: 9.423 CI:229
b. *U.A. e P.V. contributed equally to this work
115. Morini M, Roccatagliata L, Dell’Eva R, Pedemonte E, Furlan R, Minghelli S, Giunti D,
Pfeffer U, Marchese M, Noonan D, Mancardi G, Albini A, Uccelli A. Alpha Lipoic Acid is
Effective in Prevention and Treatment of Experimental Autoimmune
Encephalomyelitis. J Neuroimmunol. 2004;148/1-2 pp 146-153 IF: 2.536. CI:77
116. Uccelli A, Pedemonte E, Narciso E, Mancardi G. Biological markers of the inflammatory
phase of multiple sclerosis. Neurol Sci. 2003; 24 (5): S271-4. IF: 1.783 CI:21
117. Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E,
Noonan D, Albini A, Bernardi G, Mancardi G, Battistini L, Uccelli A. Phenotypic and
28
functional analysis of T cells homing into the CSF of subjects with inflammatory
diseases of the CNS. J Leukocyte Biol. 2003; 73(5):584-590 IF: 4.165 CI:117
118. Furlan R, Brambilla E, Sanvito F, Roccatagliata L, Olivieri S, Bergami A, Pluchino S,
Uccelli A, Comi G, Martino G. Vaccination with amyloid-beta peptide induces
autoimmune encephalomyelitis in C57/BL6 mice. Brain. 2003; 126: 285-291 IF:
10.103. CI:106
119. Uccelli A, Giunti D, Capello E, Roccatagliata L, Mancardi G. Experimental Autoimmune
Encephalomyelitis in the Common Marmoset Callithrix jacchus. Multiple Sclerosis
International Journal. 2003; 10:6-12 IF: N.A. CI:10
120. Mancardi G, Hart B, Roccatagliata L, Brok H, Giunti D, Bontrop R, Massacesi L, Capello E,
and Uccelli A.. Demyelination and axonal damage in a non-human primate model of
multiple sclerosis. J Neurol Sci 2001; 184:41-49. IF: 2.126. CI:62
121. Roccatagliata L, Uccelli A, Murialdo A. Guillain–Barré syndrome after reactivation of
varicella–zoster virus. New Engl J Med 2001; 344:65-66. IF: 59.558. CI:8
122. Uccelli A, Giunti D, Mancardi G, Caroli F, Fiorone M, Seri M, Hauser SL, Genain CP.
Characterization of the response to myelin basic protein in a non human primate
model for multiple sclerosis. Eur J Immunol. 2001; 31:474-479. IF: 4.179 CI:10
123. Poliani PL, Brok H, Furlan R, Ruffini F, Bergami A, Desina G, Marconi PC, Rovaris M,
Uccelli A, Glorioso JC, Penna G, Adorini L, Comi G, H.B.'t, Martino G. Delivery to the
central nervous system of a nonreplicative herpes simplex type 1 vector engineered
with the interleukin 4 gene protects rhesus monkeys from hyperacute autoimmune
encephalomyelitis. Hum Gene Ther. 2001; 12:905-920 IF: 4.062 CI:53
124. Solaro C, Murialdo A, Giunti D, Mancardi G, Uccelli A. Central and peripheral nervous
system complications following allogeneic-BMT. Eur J Neurol. 2001; 8:77-80. IF: 3.956.
CI:22
29
125. Comi G, Filippi M, Barkhof F, Durelli L, Edan G, Fernandez O, Hartung H, Seeldrayers P,
Sorensen PS, Rovaris M, Martinelli V, Hommes OR and the Early Treatment of Multiple
Sclerosis Study Group*. Effect of early interferon treatment on conversion to definite
multiple sclerosis: a randomised study. Lancet. 2001; 357:1576-1582. IF: 44.002
CI:804
c. *A. Uccelli is part of the “Early Treatment of Multiple Sclerosis Study Group”
126. Comi G, Kappos L, Clanet M, Ebers G, Fassas A, Fazekas F, Filippi M, Hartung HP,
Hertenstein B, Karussis D, Martino G, Tyndall A, van der Meché FGA and the BMT-MS
Study Group*. Guidelines for autologous blood and marrow stem cell transplantation in
multiple sclerosis: a consensus report written on behalf of the European Group for
Blood and Marrow Transplantation and the European Charcot Foundation. J Neurol.
2000 May;247(5):376-82. IF: 3.408. CI:86
d. *A. Uccelli is part of the “BMT-MS Study Group”
127. Ristori G, Giubilei F, Giunti D, Perna A, Gasperini C, Buttinelli C, Salvetti M, Uccelli A.
Myelin basic protein intramolecular spreading without disease progression in a patient
with multiple sclerosis. J Neuroimmunol. 2000; 110:240-243. IF: 2.536 CI:11
128. Solaro C, Messmer UM, Uccelli A, Leandri M, Mancardi G. Low-dose gabapentin
combined with either lamotrigine or carbamazepine can be useful therapies for
trigeminal neuralgia in multiple sclerosis. Eur Neurol. 2000; 44:45-48. IF: 1.403 CI:82
129. Brok HP, Uccelli A, Kerlero DR, Bontrop RE, Roccatagliata L, de Groot NG, Capello E
Laman JD, Nicolay K, Mancardi G, Ben Nun A, Hart BA. Myelin/oligodendrocyte
glycoprotein-induced autoimmune encephalomyelitis in common marmosets: the
encephalitogenic T cell epitope pMOG24-36 is presented by a monomorphic MHC class
II molecule. J Immunol. 2000; 165:1093-1101. IF: 4.985. CI:97
130. Solaro C, Uccelli MM, Guglieri P, Uccelli A, Mancardi G. Gabapentin is effective in
treating nocturnal painful spasms in multiple sclerosis. Multiple Sclerosis Journal 2000.
6:192-193. IF: 4.671 CI:44
30
131. Uccelli A, Ristori G, Giunti D, Seri M, Montesperelli C, Caroli F, Solaro C, Murialdo A,
Marchese M, Buttinelli C, Mancardi G, Salvetti M. Dynamics of the reactivity to MBP in
multiple sclerosis. J Neurovirol. 2000. 6 Suppl 2:S52-S56. IF: 2.569. CI:6
132. Mancardi G, Hart BA, Capello E, Brok HP, Ben Nun A, Roccatagliata L, Giunti D, Gazzola
P, Dono M, Kerlero DR, Colombo M, Uccelli A. Restricted immune responses lead to
CNS demyelination and axonal damage. J Neuroimmunol. 2000. 107:178-183. IF: 2.536
CI:12
133. Solaro C, Uccelli A, Gentile R, Lentino C, Mancardi G, Primavera A. Multiple sclerosis
and non-communicating syringomyelia: a casual association or linked diseases? Acta
Neurol Scand. 1999; 100:270-273. IF: 2.559. CI:9
134. Ristori G, Montesperelli C, Uccelli A, Giunti D, Buttinelli C, Bomprezzi R, Mancardi G,
Salvetti M. A major influence of the T cell receptor repertoire as compared to antigen
processing-presentation in the selection of myelin basic protein epitopes in multiple
sclerosis. J Neuroimmunol. 1999; 96:241-244. IF: 2.536. CI: 2
135. Jeong MC, Izikson L, Uccelli A, Brocke S, Oksenberg JR. Differential display analysis of
murine encephalitogenic mRNA. Int Immunol. 1998; 10:1819-1823. IF: 3.031 CI:3
136. Solaro C, Lunardi GL, Capello E, Inglese M, Messmer UM, Uccelli A, Mancardi G. An
open-label trial of gabapentin treatment of paroxysmal symptoms in multiple sclerosis
patients. Neurology. 1998; 51:609-611. IF: 8.166. CI:101
137. Mancardi G, Sardanelli F, Parodi RC, Melani E, Capello E, Inglese M, Ferrari A, Sormani
MP, Ottonello C, Levrero F, Uccelli A, Bruzzi P. Effect of copolymer-1 on serial
gadolinium-enhanced MRI in relapsing remitting multiple sclerosis. Neurology 1998;
50:1127-1133. IF: 8.166. CI:85
138. Uccelli A, Giunti D, Salvetti M, Ristori G, Fenoglio D, Abbruzzese, Mancardi G. A
restricted T cell response to myelin basic protein (MBP) is stable in multiple sclerosis
(MS) patients. Clin Exp Immunol. 1998; 111:186-192. IF: 3.148 CI:17
31
139. Li Y, Uccelli A, Laxer KD, Jeong MC, Vinters HV, Tourtellotte WW, Hauser SL, Oksenberg
JR. Local-clonal expansion of infiltrating T lymphocytes in chronic encephalitis of
Rasmussen. J Immunol. 1997; 158:1428-1437. IF: 4.85. CI:86
140. Uccelli A, Oksenberg JR, Jeong MC, Genain CP, Rombos T, Jaeger EE, Giunti D,
Lanchbury JS, Hauser SL. Characterization of the TCRB chain repertoire in the New
World monkey Callithrix jacchus. J Immunol. 1997; 158:1201-1207. IF: 4.985. CI:43
141. Mancardi GL, Capello E, Massacesi L, Inglese M, Giunti D, Nicolay K, 'T Hart BA, Uccelli
A. MRI and neuropathologic study of eae in the non human primate callithr1x jacchus.
Ital J Neurol Sci (now called Neurological Sciences) Volume 18, Issue 4, 1997, Page
33(IF Neurological Sciences 1.783) IF: 0.635. CI: 0
142. Solaro C, Inglese M, Uccelli MM, Uccelli A, Mancardi GL. Lamotrigine and gabapentin
as treatment for a paroxysmal symptom in a patient with multiple sclerosis and
Down's svndrome Ital J Neurol Sci (now called Neurological Sciences)Volume 18, Issue
4, 1997, Page 70 (IF Neurological Sciences 1.783) IF: 0.635. CI: 0
143. Genain CP, Roberts T, Davis RL, Nguyen MH, Uccelli A, Faulds D, Li Y, Hedgpeth J,
Hauser SL. Prevention of autoimmune demyelination in non-human primates by a
cAMP- specific phosphodiesterase inhibitor. P NATL ACAD SCI USA (PNAS) 1995;
92:3601-3605. IF: 9.423. CI:156
144. Schenone A, Abbruzzese M, Uccelli A, Mandich P, James R, Bellone E, Giunchedi M,
Rolando S, Capello E, Mandich P et al. Hereditary motor and sensory neuropathy with
myelin outfolding: clinical, genetic and neuropathological study of three cases. J Neurol
Sci. 1994; 122:20-27. IF: 2.126. CI:17
145. Uccelli A, Capello E, Fenoglio D, Incagliato M, Valbonesi M, Mancardi G. Intravenous
immunoglobulin, plasmalymphocytapheresis and azathioprine in chronic progressive
multiple sclerosis. Ital J Neurol Sci (now called Neurological Sciences). 1994; 15:51-53.
(IF Neurological Sciences 1.783) IF: 0.635. CI: 6
32
146. Mancardi G, Uccelli A, Bellone E, Sghirlanzoni A, Mandich P, Pareyson D, Schenone A,
Abbruzzese M, Ajmar F. 17p11. 2 duplication is a common finding in sporadic cases of
Charcot-Marie-Tooth type 1. Eur Neurol. 1994; 34:135-139. IF: 1.403 CI:14
147. Massacesi L, Vergelli M, Zehetbauer B, Liuzzi GM, Olivotto J, Ballerini C, Uccelli A,
Mancardi L, Riccio P, Amaducci L. Induction of experimental autoimmune
encephalomyelitis in rats and immune response to myelin basic protein in lipid-bound
form. J Neurol Sci. 1993; 119:91-98. IF: 2.126 CI:15
148. Valle MT, Kunkl A, Fenoglio D, Burastero SE, Manca F, Vitali V, Corvo R, Uccelli A,
Capello E, Mancardi G. Circulating lymphocyte subsets after total lymphoid irradiation
in chronic progressive multiple sclerosis. Ann Ny Acad Sci. 1993; 677:458-461. IF:
4.518. CI: 0
149. Bellone E, Mandich P, Mancardi G, Schenone A, Uccelli A, Abbruzzese M, Sghirlanzoni
A, Pareyson D, Ajmar F. Charcot-Marie-Tooth (CMT) 1a duplication at 17p11.2 in
Italian families. J Med Genet 1992; 29:492-493. IF: 5.650. CI:22
150. Tartaglione A, Martinoli O, Uccelli A, Vignolo M, Favale E. Interindividual variability of
cranioencephalic relationships as predicted by CT. J Comput Assist Tomo. 1991;
15:647-654. IF: 1.470. CI: 0
Pubblicazioni non impattate
1. Uccelli A. Dimetilfumarato per il trattamento della SM: un meccanismo d’azione
innovativo. Neurol Sci 2015 Aug 1; 1:3.
2. Lazzaro C, Uccelli A. Valutazione economica del trattamento precoce con interferone β-
1b della sindrome clinicamente isolata (CIS) e dei suoi effetti nel ritardare lo sviluppo di
sclerosi multipla clinicamente definita.2008 Practicing Neurology. Suppl. a Practicing
Medicine, Vol 18, Anno V. Feb 2008.
3. Pizzorno M, Uccelli A. Razionale per il trattamento precoce della sclerosi multipla. 2008
Practicing Neurology. Suppl. a Practicing Medicine, Vol 18, Anno V. Feb 2008.
33
4. Tartaglione A, Martinoli O, Bovio E, Vignolo M, Favale E. 1990. Proposta di un metodo
quantitative permla localizzazione intra-cranica di un punto identificato mediante TC.
Riv. Neurobiologia. 36 (2):309-311.
5. Mandich P, Bellone E, Uccelli A, Pareyson D, Ajma F. 1992. Charcot-Marie-Tooth
disease: evidence of a duplication at D17S122 locus. Boll.Soc.Ital.Biol.Sper. 68:225-
230.
6. Vitali M, Magioncalda G, Matricardi A, Uccelli A. Encefalopatia con epilessia mparziale
continua: Sindrome si Rasmussen? 1996. Boll Lega It Epil, 95/96:355-356.
7. Mandich, P., Bellone, E., Uccelli, A., Pareyson, D., Ajmar, F. Charcot-Marie-Tooth
disease: evidence of a duplication at D17S122 locus. Bollettino della Societa italiana di
biologia sperimentale Volume 68, Issue 4, April 1992, Pages 225-230
Capitoli
1. Cordano, C., Kerlero de Rosbo, N., and Uccelli, A. (2013) Mesenchymal stem cells
(MSC) as a strategy for the treatment of multiple sclerosis and other diseases of the
central nervous system. In “Stem Cell-Dependent Therapies”, (T. Haeupl and G. Gross,
eds.), De Gruyter Publisher, Berlin. pp.185-210
2. Lovato L., Kerlero de Rosbo N., Uccelli A. “Mesenchymal Stem Cells for the Treatment
of MultipleSclerosis”. Multiple Sclerosis Immunology - A Foundation for Current and
Future Treatments Editors: Yamamura Takashi; Gran Bruno. Multiple Sclerosis
Immunology 2013. Springer 2013. pp.433-455. C.I.:1
3. Muraro PA, Uccelli A. Immuno-Therapeutic Potential of Haematopioetic and Mesechymal
Stem Cell Transplantation in MS. Editors: Roland Martin, Andreas Lutterotti. Molecular
Basis of Multiple Sclerosis: The Immune System. Springer, 2009 pp237-258
4. Uccelli A., Franciotta D. Neuroimmunologia: Aspetti clinici e diagnostica di
laboratorio. MB&CARE, Collana CAREHandbook, Livorno, 2008
5. Mancardi G, Uccelli A. Malattie demielinizzanti. In C Loeb E. Favale (eds), Neurologia di
Fazio Loeb. Societa Editrice Universo; 2003. pp. 1111-32.
6. G. Corallo, Capris P, Barabino S, Cicinelli S, Mastromarino A, Bandini F, Uccelli A,
Solaro C, Zanardi S, Calabria G. Comparison of conventional automated perimetry,
short-wavelenght automated perimetry and frequency-doubling technology in the
34
assessment of patients with multiple sclerosis. In: Henson Db; Wall M. Perimetry Update
2002/2003, AMSTERDAM:Kugler Publications. pp. 97-101
7. 't Hart BA, Bontrop RE, Uccelli A. T-cell autoimmunity and EAE in nonhuman primates.
RG Landes Company, 1999 pp19-27
8. Uccelli A. Animal models of demyelination of the central nervous system. In G. Martino,
L. Adorini (Eds) From basic immunology to immune-mediated demyelination. Springer,
1999 pp233-245 C.I.: 5
9. Uccelli A, Mancardi G, Giunti D., Brok H., Roccatagliata L., Capello E., T’Hart B.
Experimental autoimmune encephalomyelitis in the common marmoset Callithrix
jacchus. In D. Gambi, P.A. Muraro, A. Lugaresi (eds), Advances in the
immunopathogenesis of Multiple Sclerosis. Springer, 1999. pp. 79-84.
10. Uccelli, A. & Lanchbury, J.S. (1997) Analysis of TCR rearrangements using inverse-PCR.
In: The Antigen T Cell Receptor: Selected Protocols and Applications (ed. by
J.R.Oksenberg),. R.G. Landes and Chapman & Hall, Austin, TX. pp. 266–286
11. Giunti D, Uccelli A. (1997) Bio-computing T-cell receptor sequences. In: The Antigen T
Cell Receptor: Selected Protocols and Applications (ed. by J.R.Oksenberg),. R.G. Landes
and Chapman & Hall, Austin, TX
12. Mancardi G, Uccelli A. Malattie demielinizzanti. In Fazio C. Loeb C. (eds) Neurologia ,
Società Editrice Universo, 26:879-901,1996.
13. Uccelli A, Hauser SL. Multiple Sclerosis and related demyelinating diseases. In
Lichtenstein LM, Fauci AS (eds) Current therapy in Allergy, Immunology and
Rheumatology, Fifth Edition. W.B. Sanders. 379-386,1996.
14. Uccelli A, Hauser SL. Optic Neuritis. In: Guide to Clinical Neurology. Mohr, J.P. and
Gautier, J.C, Eds, Churchill Livingstone, New York. 1995. Pp 861-862
top related